CN211856478U

CN211856478U - Medicine feeding device of high performance liquid chromatograph

Info

Publication number: CN211856478U
Application number: CN201922106490.4U
Authority: CN
Inventors: 李昌华
Original assignee: Sichuan Ziren Pharmaceutical Co ltd
Current assignee: Sichuan Ziren Pharmaceutical Co ltd
Priority date: 2019-11-29
Filing date: 2019-11-29
Publication date: 2020-11-03
Anticipated expiration: 2029-11-29

Abstract

The utility model discloses a medicine feeding device of a high performance liquid chromatograph, which comprises a box body, wherein a solution box is fixedly arranged on one side of the box body, a movable plate is connected in the box body in a sliding way, a screw is arranged on the top of the movable plate, a slider is connected with the outer ring of the screw in a threaded way, a support frame is welded on the top of the slider, a liquid pump is fixedly arranged on the top of the support frame, a conveying pipe is fixedly sleeved on a liquid inlet of the liquid pump, the conveying pipe penetrates through the box body and extends to, and the connecting pipe other end runs through fly leaf bottom fixedly connected with and annotates the liquid head, annotates liquid head below and is equipped with the chromatographic column, and spring reaction force can make the movable block pass the fixed block, and the iron plate on the movable block can inhale mutually with the magnetic path on the connecting block, realizes the fixed to the mounting panel, and then fixed chromatographic column, convenient to detach and installation are convenient for change chromatographic column, the operation of being convenient for.

Description

Medicine feeding device of high performance liquid chromatograph

Technical Field

The utility model relates to a high performance liquid chromatograph field especially relates to a high performance liquid chromatograph advances medicine device.

Background

A High Performance Liquid Chromatograph (HPLC) is an instrument and equipment which applies the principle of high performance liquid chromatography and is mainly used for analyzing organic compounds with high boiling points, difficult volatilization, unstable heating and large molecular weight. It is composed of liquid storage device, pump, sample injector, chromatographic column, detector and recorder. The mobile phase in the liquid storage device is pumped into the system by a high pressure pump, the sample solution enters the mobile phase through the sample injector and is loaded into a chromatographic column (stationary phase) by the mobile phase, and because each component in the sample solution has different distribution coefficients in two phases, when the two phases do relative motion, through repeated adsorption-desorption distribution processes, each component generates a large difference in moving speed, is separated into single components and sequentially flows out of the column, when the sample solution passes through the detector, the concentration of the sample is converted into an electric signal and is transmitted to a recorder, and data is printed in a map form. HPLC is widely used in life sciences, food sciences, pharmaceutical research, and environmental research. .

This application improves under prior art, and among the prior art, the chromatographic column adopts fixed mounting in the medicine feeding device of current high performance liquid chromatograph, and when using for a long time, the sieve on the chromatographic column probably blocks up, needs wash or change, and the not convenient to detach is not convenient for change.

SUMMERY OF THE UTILITY MODEL

The utility model aims at solving the defects existing in the prior art and providing a medicine feeding device of a high performance liquid chromatograph.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

the utility model provides a high performance liquid chromatograph advances medicine device, includes the box, box one side fixed mounting has the solution tank, sliding connection has the fly leaf in the box, the fly leaf top is equipped with the screw rod, screw rod outer lane threaded connection has the slider, the welding of slider top has the support frame, support frame top fixed mounting has the liquid pump, the fixed conveyer pipe that has cup jointed of liquid pump inlet, the conveyer pipe runs through the box and extends to inside the solution tank, the fixed connecting pipe that has cup jointed of liquid pump outlet outer wall, and the connecting pipe other end runs through fly leaf bottom fixedly connected with and annotates the liquid head, it is equipped with the chromatographic column to annotate.

As a further description of the above technical solution: the supporting plates are symmetrically welded to the top of the movable plate and are rotatably connected with the screw rod, and one end, extending out of one group of the supporting plates, of the screw rod is fixedly connected with a motor fixedly mounted on the top of the movable plate.

As a further description of the above technical solution: the chromatographic column both sides are equipped with the electric telescopic handle of symmetric distribution, electric telescopic handle and bottom half inner wall fixed mounting, and electric telescopic handle drive end and fly leaf bottom fixed connection.

As a further description of the above technical solution: the fixed cover of chromatographic column bottom outer wall has connect the sleeve, sleeve outer lane threaded connection has the fixing base, the welding of fixing base bottom has the mounting panel, the equal sliding connection in mounting panel both sides has the movable block, the one end outer wall sliding connection that the movable block stretches out the mounting panel has with box welded fixed block, the one end that the movable block stretches out the fixed block is connected with the connecting block, the one end welding that the movable block was kept away from to the connecting block has box sliding connection's slide, the slide is kept away from one side welding of connecting block and is had box sliding connection's movable.

As a further description of the above technical solution: the one end fixedly connected with that the movable block stretched into the mounting panel and mounting panel fixed connection's spring, the one end fixed mounting that the movable block is close to the connecting block has the iron plate.

As a further description of the above technical solution: the connecting block is close to one side fixed mounting of iron plate has the magnetic path, connecting block and magnetic path height all slightly are less than the height of movable block.

The utility model discloses following beneficial effect has:

1. the utility model discloses in accomplish this device integral erection back, during the use, start the liquid pump, the liquid pump passes through the conveyer pipe and takes solution in the solution tank out and send to annotate liquid head department, starter motor and electric telescopic handle, motor output shaft rotates and drives the screw rod and rotate and then drive the slider and remove, the slider drives annotates the liquid head and removes directly over the chromatographic column, electric telescopic handle drives the fly leaf and moves down for annotate the liquid head and be located the chromatographic column and slightly top the position, can annotate the liquid to the chromatographic column and carry out the analysis, realize high performance liquid chromatograph's the medicine that advances.

2. When the utility model is used for a long time, the chromatographic column can be blocked or damaged, the chromatographic column needs to be disassembled, cleaned or replaced, the movable rod is pushed, the movable rod moves to drive the sliding plate to move and further drive the connecting block and the magnetic block to move, the movable block enters the mounting plate through the connecting block and the magnetic block, the spring contracts and can pull the mounting plate to enable the mounting plate to be integrally separated from the box body, the chromatographic column can be cleaned or replaced by rotating the chromatographic column to enable the chromatographic column outer ring sleeve to be separated from the fixing seat, after the cleaning or replacement is finished, the chromatographic column sleeved with the sleeve is screwed into the fixing seat, the movable block enters the mounting plate and pushes the mounting plate into the box body through sliding the movable block, when the movable block reaches the through groove on the fixed block, the reaction force of the spring can enable the movable block to pass through, the mounting plate is fixed, so that the chromatographic column is fixed, the dismounting and the mounting are convenient, the chromatographic column is convenient to replace, and the operation is convenient.

Drawings

Fig. 1 is a schematic structural diagram of a drug feeding device of a high performance liquid chromatograph according to the present invention;

fig. 2 is an enlarged schematic structural view of a point a in fig. 1 according to the present invention;

fig. 3 is an enlarged schematic structural diagram of the position B of fig. 1 in the present invention.

Illustration of the drawings:

1-box body, 2-movable plate, 3-screw rod, 4-slide block, 5-support frame, 6-liquid pump, 7-conveying pipe, 8-solution box, 9-liquid injection head, 10-movable rod, 11-mounting plate, 12-fixed seat, 13-sleeve, 14-chromatographic column, 15-movable block, 16-fixed block, 17-iron block, 18-magnetic block, 19-connecting block and 20-sliding plate.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention; the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance, and furthermore, unless otherwise explicitly stated or limited, the terms "mounted," "connected," and "connected" are to be construed broadly and may be, for example, fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

Referring to fig. 1-3, the utility model provides a high performance liquid chromatograph medicine feeding device, including box 1, box 1 one side fixed mounting has solution tank 8, sliding connection has fly leaf 2 in box 1, fly leaf 2 top is equipped with screw rod 3, screw rod 3 outer lane threaded connection has slider 4, slider 4 top welding has support frame 5, support frame 5 top fixed mounting has liquid pump 6, liquid pump 6 inlet is fixed cup jointed with conveyer pipe 7, conveyer pipe 7 runs through box 1 and extends to the inside of solution tank 8, liquid pump 6 liquid outlet outer wall is fixed cup jointed with the connecting pipe, and the connecting pipe other end runs through fly leaf 2 bottom fixed connection has annotates liquid head 9, annotates liquid head 9 below and is equipped with chromatographic column 14, realizes the medicine feeding;

referring to fig. 1, in the present application, symmetrically distributed support plates are welded on the top of a movable plate 2, and the support plates are rotatably connected with a screw 3, one end of the screw 3 extending out of one of the support plates is fixedly connected with a motor fixedly mounted on the top of the movable plate 2, the support plates support the screw 3, and an output shaft of the motor drives the screw 3 to rotate;

referring to fig. 1, in the application, electric telescopic rods are symmetrically arranged on two sides of a chromatographic column 14, the electric telescopic rods are fixedly mounted on the inner wall of the bottom of a box body 1, and the driving ends of the electric telescopic rods and the bottom of a movable plate 2 are fixedly connected with the driving end of the electric telescopic rod to drive the movable plate 2 to move so as to adjust a liquid injection head 9;

referring to fig. 1-3, in the application, a sleeve 13 is fixedly sleeved on the outer wall of the bottom of a chromatographic column 14, a fixed seat 12 is in threaded connection with the outer ring of the sleeve 13, a mounting plate 11 is welded at the bottom of the fixed seat 12, movable blocks 15 are slidably connected to both sides of the mounting plate 11, a fixed block 16 welded to a box body 1 is slidably connected to the outer wall of one end, extending out of the mounting plate 11, of each movable block 15, a connecting block 19 is connected to one end, extending out of the fixed block 16, of each movable block 15, a sliding plate 20 slidably connected to the box body 1 is welded to one end, away from the corresponding movable block 15, of each connecting block 19, and a;

referring to fig. 1 and 3, in the present application, one end of the movable block 15, which extends into the mounting plate 11, is fixedly connected with a spring fixedly connected with the mounting plate 11, one end of the movable block 15, which is close to the connecting block 19, is fixedly provided with an iron block 17, the spring helps the movable block 15 to pass through the fixed block 16, and the iron block 17 helps to attract the magnetic block 18 to fix the movable block 15;

referring to fig. 3, in the application, a magnetic block 18 is fixedly mounted on one side of the connecting block 19 close to the iron block 17, and the heights of the connecting block 19 and the magnetic block 18 are slightly smaller than the height of the movable block 15, so that the connecting block 19 and the magnetic block 18 can penetrate through the fixed block 16 to enable the movable block 15 to enter the mounting plate 11.

The working principle is as follows:

in the application, after the device is integrally installed, when the device is used, the liquid pump 6 is started, the liquid pump 6 pumps out the solution in the solution tank 8 through the conveying pipe 7 and sends the solution to the liquid injection head 9, the motor and the electric telescopic rod are started, the motor output shaft rotates to drive the screw rod 3 to rotate and further drive the sliding block 4 to move, the sliding block 4 drives the liquid injection head 9 to move right above the chromatographic column 14, and the electric telescopic rod drives the movable plate 2 to move downwards, so that the liquid injection head 9 is positioned slightly above the chromatographic column 14, the liquid injection head 14 can be analyzed, and the medicine feeding of the high performance liquid chromatograph is realized;

in the application, after long-time use, the chromatographic column 14 may be blocked or damaged, at this time, the chromatographic column 14 needs to be disassembled, cleaned or replaced, at this time, the movable rod 10 is pushed, the movable rod 10 moves to drive the sliding plate 20 to move and further drive the connecting block 19 and the magnetic block 18 to move, the connecting block 19 and the magnetic block 18 enable the movable block 15 to enter the mounting plate 11, the spring contracts, the mounting plate 11 can be pulled to enable the mounting plate 11 to be integrally separated from the box body 1, the chromatographic column 14 is rotated to enable the outer ring sleeve 13 of the chromatographic column 14 to be separated from the fixing seat 12 to clean or replace the chromatographic column 14, after cleaning or replacement is completed, the chromatographic column 14 sleeved with the sleeve 13 is screwed into the fixing seat 12, the movable block 15 is slid to enable the movable block 15 to enter the mounting plate 11 and push the mounting plate 11 into the box body 1, when the movable block 15 reaches the through groove, the iron block 17 on the movable block 15 can attract the magnetic block 18 on the connecting block 19, so that the mounting plate 11 is fixed, the chromatographic column 14 is further fixed, the dismounting and mounting are convenient, the chromatographic column 14 is convenient to replace, and the operation is convenient.

Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications and variations can be made in the embodiments or in part of the technical features of the embodiments without departing from the spirit and the scope of the invention.

Claims

1. The utility model provides a high performance liquid chromatograph advances medicine device, includes box (1), its characterized in that: box (1) one side fixed mounting has solution tank (8), sliding connection has fly leaf (2) in box (1), fly leaf (2) top is equipped with screw rod (3), screw rod (3) outer lane threaded connection has slider (4), slider (4) top welding has support frame (5), support frame (5) top fixed mounting has liquid pump (6), the fixed cover of liquid pump (6) inlet has been cup jointed conveyer pipe (7), conveyer pipe (7) run through box (1) and extend to inside solution tank (8), liquid pump (6) liquid outlet outer wall is fixed to have cup jointed the connecting pipe, and the connecting pipe other end runs through fly leaf (2) bottom fixedly connected with and annotates liquid head (9), it is equipped with chromatographic column (14) to annotate liquid head (9) below.

2. The hplc drug feeding device of claim 1, wherein: the supporting plates are symmetrically welded to the top of the movable plate (2) and rotatably connected with the screw rods (3), and one end, extending out of one group of the supporting plates, of each screw rod (3) is fixedly connected with a motor fixedly mounted on the top of the movable plate (2).

3. The hplc drug feeding device of claim 1, wherein: the chromatographic column (14) both sides are equipped with the electric telescopic handle of symmetric distribution, electric telescopic handle and box (1) bottom inner wall fixed mounting, and electric telescopic handle drive end and fly leaf (2) bottom fixed connection.

4. The hplc drug feeding device of claim 1, wherein: chromatographic column (14) bottom outer wall is fixed to have cup jointed sleeve (13), sleeve (13) outer lane threaded connection has fixing base (12), fixing base (12) bottom welding has mounting panel (11), the equal sliding connection in mounting panel (11) both sides has movable block (15), the one end outer wall sliding connection that mounting panel (11) were stretched out to movable block (15) has fixed block (16) with box (1) welded, the one end that fixed block (16) were stretched out to movable block (15) is connected with connecting block (19), the one end welding that movable block (15) were kept away from in connecting block (19) has box (1) sliding connection's slide (20), one side welding that connecting block (19) were kept away from in slide (20) has box (1) sliding connection's movable rod (10).

5. The hplc drug feeding device of claim 4, wherein: the one end fixedly connected with that mounting panel (11) was stretched into in movable block (15) and mounting panel (11) fixed connection's spring, the one end fixed mounting that movable block (15) are close to connecting block (19) has iron plate (17).

6. The hplc drug feeding device of claim 4, wherein: one side of the connecting block (19) close to the iron block (17) is fixedly provided with a magnetic block (18), and the heights of the connecting block (19) and the magnetic block (18) are slightly smaller than the height of the movable block (15).