CN211799272U - Filtration equipment for bio-pharmaceuticals - Google Patents
Filtration equipment for bio-pharmaceuticals Download PDFInfo
- Publication number
- CN211799272U CN211799272U CN202020381178.6U CN202020381178U CN211799272U CN 211799272 U CN211799272 U CN 211799272U CN 202020381178 U CN202020381178 U CN 202020381178U CN 211799272 U CN211799272 U CN 211799272U
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- China
- Prior art keywords
- filtering
- cylinder
- motor
- filter
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000001914 filtration Methods 0.000 title claims abstract description 81
- 229960000074 biopharmaceutical Drugs 0.000 title claims abstract description 23
- 239000007788 liquid Substances 0.000 claims abstract description 43
- 238000007789 sealing Methods 0.000 claims abstract description 22
- 239000003814 drug Substances 0.000 claims abstract description 14
- 239000011148 porous material Substances 0.000 claims description 2
- 239000002994 raw material Substances 0.000 abstract description 6
- 238000000926 separation method Methods 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 description 9
- 238000004519 manufacturing process Methods 0.000 description 6
- 230000009471 action Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 2
- 229930182566 Gentamicin Natural products 0.000 description 1
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 description 1
- OJMMVQQUTAEWLP-UHFFFAOYSA-N Lincomycin Natural products CN1CC(CCC)CC1C(=O)NC(C(C)O)C1C(O)C(O)C(O)C(SC)O1 OJMMVQQUTAEWLP-UHFFFAOYSA-N 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 229960003276 erythromycin Drugs 0.000 description 1
- 229960002518 gentamicin Drugs 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- OJMMVQQUTAEWLP-KIDUDLJLSA-N lincomycin Chemical compound CN1C[C@H](CCC)C[C@H]1C(=O)N[C@H]([C@@H](C)O)[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](SC)O1 OJMMVQQUTAEWLP-KIDUDLJLSA-N 0.000 description 1
- 229960005287 lincomycin Drugs 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The utility model discloses a filtration equipment for bio-pharmaceuticals belongs to bio-pharmaceuticals equipment technical field. The filtering equipment comprises a cylinder body with a sealing cover, wherein the cylinder body comprises an outer cylinder and a filtering cylinder, the filtering cylinder is arranged inside the outer cylinder, a cavity is formed between the outer cylinder and the filtering cylinder, a plurality of through holes are formed in the inner wall of the filtering cylinder along the circumferential direction, a motor is arranged at the bottom of the filtering cylinder, the motor is arranged outside the outer cylinder, an output shaft of the motor is connected with a bottom shaft of the filtering cylinder, a filtering device used for bearing liquid medicine is further arranged inside the filtering cylinder, the top of the filtering device is detachably connected with the inner side wall of the filtering cylinder, and the; the utility model discloses a setting up the inner wall of filter equipment and cartridge filter can dismantle and be connected, can be according to the requirement of biological liquid medicine raw materials, the filter screen in the different apertures of reasonable selection is in order to realize filtering the purpose, through setting up urceolus, cartridge filter, motor and with filter equipment, realizes the dregs of a decoction and the liquid medicine separation of the bio-pharmaceuticals raw materials in the filter screen.
Description
Technical Field
The utility model relates to a bio-pharmaceuticals equipment technical field, concretely relates to filtration equipment for bio-pharmaceuticals.
Background
The biological medicine refers to a product for prevention, treatment and diagnosis which is manufactured by using organisms, biological tissues, cells, body fluids and the like by comprehensively utilizing principles and methods of physics, chemistry, biochemistry, biotechnology, pharmacy and other subjects and applying the research results of biology, medicine, biochemistry and the like, and the biological medicine product comprises: vitamins, erythromycin, lincomycin and the like, penicillin, streptomycin, gentamicin and the like for injection are prepared by fermenting different microorganisms, and the development of the biological pharmaceutical technology provides guarantee for the life health and the life quality of people;
in the process of biological pharmacy, because the application fields of biological pharmacy intermediates are different, the purity requirements of different kinds of biological pharmacy intermediates on the intermediates in the production and preparation processes are different, however, although the purification treatment of the biological pharmacy intermediates can be completed by applying the filtering equipment in the prior art, the filtering equipment with different aperture diameters is needed for filtering the medicine intermediates with different purity requirements, and the filter screen of the filtering equipment cannot be detached, so that the filter screen is not convenient to replace, the equipment investment of pharmaceutical production is increased, and the production cost is high; therefore, the filtering equipment for the bio-pharmaceuticals, which can replace the filter screen, has great practical value.
SUMMERY OF THE UTILITY MODEL
The utility model aims at overcoming the problems in the prior art and providing a filtering device for bio-pharmaceuticals.
The utility model provides a filtration equipment for bio-pharmaceuticals, including the barrel that has sealed lid, the barrel includes urceolus and cartridge filter, the cartridge filter is established in the inside of urceolus, and forms the cavity that is used for collecting liquid between urceolus and the cartridge filter, a plurality of through-holes that are used for the liquid outflow are seted up to the cartridge filter inner wall along circumference, the bottom of cartridge filter is equipped with and is used for making cartridge filter pivoted motor, the motor is established in the outside of urceolus, and the output shaft of motor and the bottom hub connection of cartridge filter, the inside filter equipment who is used for accepting the liquid medicine that still is equipped with of cartridge filter, and filter equipment's top can dismantle with the inside wall of cartridge filter and be connected.
Preferably, the top of the filtering device is provided with a fixing frame, and the fixing frame is in threaded connection with the inner side wall of the filter cylinder.
Preferably, the top of the sealing cover is provided with a liquid inlet pipe, and the liquid inlet pipe penetrates through the bottom of the sealing cover from the top of the sealing cover and is communicated with the filter screen.
Preferably, a liquid outlet pipe communicated with the cavity is arranged at the bottom of the outer barrel, and a valve is arranged on the liquid outlet pipe.
Preferably, the bottom of the sealing cover is provided with a sealing ring.
Preferably, the filtering device is a filter screen with different pore sizes.
Preferably, a plurality of springs are provided between the inner bottom wall of the outer cartridge and the outer bottom wall of the filter cartridge.
Preferably, an observation window for observing the liquid level height of the liquid in the cavity is longitudinally arranged on the outer barrel.
Compared with the prior art, the beneficial effects of the utility model are that: the utility model discloses a thawing apparatus.
The utility model can reasonably select the filter screens with different apertures to realize the filtering requirement according to the requirement of the biological liquid medicine raw material by arranging the filtering device, the fixing frame and the inner side wall of the filter cylinder in threaded connection, and by arranging the outer cylinder, the filter cylinder, the motor fixing frame and the filtering device, when the motor rotates, the motor drives the filter cartridge to rotate, the filter generation cartridge rotates to drive the filter device connected with the filter cartridge to rotate, then the biological pharmaceutical raw materials injected into the filter screen separate the dregs of a decoction from the liquid medicine of the biological pharmaceutical raw materials in the filter screen under the action of centrifugal force, the liquid medicine flows out of the filter screen through the through holes arranged on the wall of the filter screen and flows into the outer cylinder, thereby realizing the filtration of the biological pharmaceutical liquid medicine, through setting up the spring, so can alleviate the vibration range between urceolus and the cartridge filter, reduce the loss of equipment.
Drawings
Fig. 1 is a schematic sectional structure of the present invention;
fig. 2 is a schematic perspective view of the present invention.
Description of reference numerals:
1. the device comprises a cylinder body, 1-1 parts of an outer cylinder, 1-2 parts of a filter cylinder, 2 parts of a sealing cover, 3 parts of a motor, 4 parts of a filter device, 5 parts of a fixing frame, 6 parts of a liquid inlet pipe, 7 parts of a liquid outlet pipe and 8 parts of an observation window.
Detailed Description
The following detailed description of the present invention is provided in conjunction with the accompanying drawings, but it should be understood that the scope of the present invention is not limited by the following detailed description. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
Example 1
As shown in the figures 1-2, the filtering apparatus for bio-pharmaceuticals provided by the present invention comprises a barrel 1 with a sealing cover 2, the barrel 1 comprises an outer barrel 1-1 and a filtering barrel 1-2, the filtering barrel 1-2 is arranged inside the outer barrel 1-1, a cavity for collecting liquid is formed between the outer barrel 1-1 and the filtering barrel 1-2, a plurality of through holes for liquid to flow out are arranged on the inner wall of the filtering barrel 1-2 along the circumferential direction, a motor 3 for rotating the filtering barrel 1-2 is arranged at the bottom of the filtering barrel 1-2, the motor 3 is arranged outside the outer barrel 1-1, the output shaft of the motor 3 is connected with the bottom shaft of the filtering barrel 1-2, a filtering device 4 for receiving liquid medicine is further arranged inside the filtering barrel 1-2, and the top of the filtering device 4 is detachably connected with the inner side wall of the filtering barrel 1-2, the motor 3 is electrically connected with a power supply through a control switch.
In this embodiment, in order to solve the problems of the prior art that the filter screen of the filtering apparatus for bio-pharmaceuticals cannot be disassembled and the production cost is high, when the apparatus of the present application is used, the intermediate or raw material of bio-pharmaceuticals produced is transported into the filtering cylinder 1, the sealing cover 2 is hermetically disposed on the cylinder 1, then the control switch of the motor 3 disposed at the bottom of the cylinder 1 is turned on, the motor 3 rotates to drive the filtering cylinder 1-2 connected with the output shaft of the motor 3 to rotate, because the filtering apparatus 4 is connected with the filtering cylinder 1-2 by a screw thread or a clamping manner, the filtering apparatus 4 can selectively select filtering apparatuses with different apertures according to the production requirements of the intermediate of bio-pharmaceuticals for satisfying the purification requirements of the intermediate of bio-pharmaceuticals, because the filtering apparatus 4 is connected with the filtering cylinder 1-2, therefore, the filter cartridge 1-2 rotates to drive the filter device 4 to rotate, the filter device 4 separates liquid and waste residues of the filter device 4 under the action of centrifugal force, the liquid enters the filter cartridge 1-2 and flows into a cavity between the outer cartridge 1-1 and the filter cartridge 1-2 along through holes arranged on the inner wall of the filter cartridge 1-2 under the action of centrifugal force, and then is discharged by a liquid discharge pipe 7 communicated with the cavity, the motor 3 is fixed by a motor frame, and the motor frame is arranged on a support leg below the cartridge.
The detachable connection mode between the filter device 4 and the filter cartridge 1-2 is various, the filter device 4 is connected in a threaded connection mode, threads on the outer side wall of a fixing frame 5 fixedly connected to the filter device 4 are connected with the threads arranged on the filter cartridge 1-2, and in order to ensure the stability of the filter device 4, the rotation direction of the motor 3 is consistent with the connection direction of the threads; therefore, the top of the filtering device 4 is provided with a fixing frame 5, and the fixing frame 5 is in threaded connection with the inner side wall of the filtering cylinder 1-2.
In order to prevent the injury to operators in the filtering process, the liquid to be filtered is conveyed into the filtering device through the liquid inlet pipe 6, the top of the sealing cover 2 is provided with the liquid inlet pipe 6, and the liquid inlet pipe 6 penetrates through the bottom of the sealing cover 2 from the top of the sealing cover 2 and is communicated with the filtering device 4.
In order to discharge the filtered liquid in the filter device 4 in time by opening the valve on the liquid outlet pipe 7, a liquid outlet pipe 7 communicated with the cavity is arranged at the bottom of the outer cylinder 1-1, and the valve is arranged on the liquid outlet pipe 7.
In order to ensure the sealing performance of the sealing cover 2, a sealing ring is arranged at the bottom of the sealing cover 2.
In order to meet the purity requirement of the intermediate of the biological pharmacy, the filtering device 4 is composed of filter screens with different apertures, and when filtering, the filtering device 4 of the filter screens with different apertures is reasonably selected according to the requirement of a production plan and is in threaded connection with the filter cylinder 1-2, so as to realize the filtering requirement.
In order to reduce the vibration amplitude between the outer cylinder and the filter cylinder and reduce the loss of equipment, a plurality of springs are arranged between the inner side wall of the outer cylinder 1-1 and the bottom of the filter cylinder 1-2.
In order to discharge the filtered liquid in the cavity in time and improve the filtering efficiency, an observation window for observing the liquid level height of the liquid in the cavity is arranged on the outer cylinder 1-1 along the longitudinal direction.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (8)
1. The filtering equipment for the bio-pharmaceuticals is characterized by comprising a cylinder body (1) with a sealing cover (2), wherein the cylinder body (1) comprises an outer cylinder (1-1) and a filtering cylinder (1-2), the filtering cylinder (1-2) is arranged inside the outer cylinder (1-1), a cavity for collecting liquid is formed between the outer cylinder (1-1) and the filtering cylinder (1-2), a plurality of through holes for liquid to flow out are formed in the inner wall of the filtering cylinder (1-2) along the circumferential direction, a motor (3) for enabling the filtering cylinder (1-2) to rotate is arranged at the bottom of the filtering cylinder (1-2), the motor (3) is arranged outside the outer cylinder (1-1), an output shaft of the motor (3) is connected with a bottom shaft of the filtering cylinder (1-2), a filtering device (4) for receiving liquid medicine is further arranged inside the filtering cylinder (1-2), and the top of the filtering device (4) is detachably connected with the inner side wall of the filter cartridge (1-2), and the motor (3) is electrically connected with a power supply through a control switch.
2. A filtering apparatus for bio-pharmaceuticals according to claim 1, wherein the top of the filtering means (4) is provided with a holder (5), the holder (5) being in threaded connection with the inner side wall of the filter cartridge (1-2).
3. A filtering device for biopharmaceuticals according to claim 1, wherein the top of the sealing lid (2) is provided with a liquid inlet pipe (6), the liquid inlet pipe (6) extending from the top of the sealing lid (2) through the bottom of the sealing lid (2) and communicating with the filtering means (4).
4. A filtering apparatus for biopharmaceuticals according to claim 1, wherein a liquid outlet tube (7) communicating with the cavity is provided at the bottom of said outer cylinder (1-1), said liquid outlet tube (7) being provided with a valve.
5. A filtering device for biopharmaceuticals according to claim 1, wherein the bottom of the sealing lid (2) is provided with a sealing ring.
6. A filtering device for biopharmaceuticals according to claim 1, wherein said filtering means (4) are screens of different pore sizes.
7. A filtering device for biopharmaceuticals according to claim 1, wherein a plurality of springs are provided between the inner bottom wall of the outer cartridge (1-1) and the outer bottom wall of the filter cartridge (1-2).
8. A filtering apparatus for biopharmaceuticals according to claim 1, wherein said outer cartridge (1-1) is provided with an observation window in longitudinal direction for observing the level of liquid in the cavity.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202020381178.6U CN211799272U (en) | 2020-03-23 | 2020-03-23 | Filtration equipment for bio-pharmaceuticals |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202020381178.6U CN211799272U (en) | 2020-03-23 | 2020-03-23 | Filtration equipment for bio-pharmaceuticals |
Publications (1)
Publication Number | Publication Date |
---|---|
CN211799272U true CN211799272U (en) | 2020-10-30 |
Family
ID=73010471
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202020381178.6U Expired - Fee Related CN211799272U (en) | 2020-03-23 | 2020-03-23 | Filtration equipment for bio-pharmaceuticals |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN211799272U (en) |
-
2020
- 2020-03-23 CN CN202020381178.6U patent/CN211799272U/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20201030 |