CN211750128U - Tissue marking needle - Google Patents

Tissue marking needle Download PDF

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Publication number
CN211750128U
CN211750128U CN201921620809.9U CN201921620809U CN211750128U CN 211750128 U CN211750128 U CN 211750128U CN 201921620809 U CN201921620809 U CN 201921620809U CN 211750128 U CN211750128 U CN 211750128U
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tissue
base
marking needle
hook
tissue marking
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CN201921620809.9U
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李坚
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Abstract

An embodiment of the utility model provides a tissue marking needle, this tissue marking needle include base and coupler body, wherein are provided with luminous coating on the base, and the coupler body sets up outside the base, links to each other the base with the tissue that needs the mark, during the use, through the biopsy pore of intestines mirror, can be conveniently with tissue marking needle apply the tissue that needs the mark on, reduced surgeon's the operation degree of difficulty, also reduced patient's misery.

Description

Tissue marking needle
Technical Field
The utility model belongs to the technical field of the tissue mark, concretely relates to tissue mark needle.
Background
With the increasing popularity of imaging screening programs, most tumors are detected as small, non-palpable or shallow recessive lesions. Accurate positioning of such tumors is critical to allow surgical removal of all tumors with sufficient margins. If the tumor is not completely resected, the patient needs to undergo additional surgery to remove any remaining cancerous tissue. Accurate positioning also helps to avoid cutting too much normal tissue.
Non-palpable lesions or abnormalities can be examined by routine or screening angiography. If the abnormality is not palpable, a tissue biopsy is typically performed using a Vacuum Assisted Biopsy (VAB) needle or core biopsy needle during the diagnostic procedure. After biopsy, an initial tissue marker is placed so that the site can be located during subsequent procedures. After analyzing the biopsy sample, if the sample is benign, the tissue markers are retained in the patient for a long period of time; if the biopsy shows a cancerous tumor, the patient is surgically operated to remove the tumor.
The existing tissue marking method has the following problems: radioactive materials may be introduced, some radioisotopes have a short half-life, limiting the time between administration and surgery; two types of markers need to be placed at the surgical site, first after biopsy to place a tissue marker to mark the biopsy site. Additional marking tools such as radiotracers or radioactive particles are then placed at the same site, and this repeated procedure adds to the work of the surgical and radiology teams as well as to the pain and risk to the patient.
In conclusion, there is still a need for new tissue markers.
SUMMERY OF THE UTILITY MODEL
For solving prior art, a problem for tissue marker existence in the operation, the embodiment of the utility model provides a through providing a tissue marker needle, this tissue marker needle includes base and coupler body, wherein is provided with luminous coating on the base, and the coupler body setting links to each other the base with the tissue that needs the mark with the base outside, during the use, through the biopsy pore of intestines mirror, can apply the tissue marker needle to the tissue that needs the mark conveniently on, reduced surgeon's the operation degree of difficulty, also reduced patient's misery.
One of the embodiments of the utility model adopts the following technical scheme:
a tissue marking needle comprising
A base on which a luminescent coating is disposed;
the hook body is arranged outside the base and fixedly connected with the base.
The tissue marking needle provided by the embodiment of the utility model is provided with the luminous coating on the base, on one hand, the tissue marking needle plays a role of marking, and can accurately position and mark the tissue part of biopsy; on the other hand, the mark is convenient to find again. The hook may penetrate into tissue for securing the base to the tissue. When in use, the tissue marking needle can be conveniently applied to the tissue to be marked through the biopsy pore canal of the enteroscope, thereby reducing the operation difficulty of a surgeon and the pain of a patient.
Preferably, the material of the tissue marking needle is a degradable material.
The material of the tissue marking needle is degradable material, so that the tissue marking needle can be completely degraded in the body, and the operation for taking the tissue marking needle out of the body is not needed to be carried out again. Solves the problem that the marker needs to be taken out through a secondary operation in the prior art.
Further preferably, the degradable material comprises Polylactide (PLA), poly (lactide-co-glycolide) (PLGA), polyanhydride, polyorthoester, poly (N- (2-hydroxypropyl) methacrylamide), poly (dl-lactide) (DLPLA), poly (l-lactide) (LPLA), Polyglycolide (PGA), Polydioxanone (PDO), poly (glycolide-co-trimethylene carbonate) (PGA-TMC).
Still further preferably, the degradable material further comprises a copolymer of one or more of poly (l-lactide-co-glycolide) (PGA-LPLA), poly (dl-lactide-co-glycolide) (PGA-DLPLA), poly (l-lactide-co-dl-lactide) (LPLA-DLPLA), poly (glycolide-co-trimethylene carbonate-co-dioxanone) (PDO-PGA-TMC) and polyarginine.
The degradable material can be degraded in vivo, and is safe and nontoxic.
Preferably, the base (10) is in the shape of a cylinder, and the hook is fixedly arranged on the side surface of the cylinder.
The hook body is fixedly arranged on the side surface of the cylinder, so that the tissue marking needle can be conveniently fixed on the tissue to be marked.
Preferably, the upper bottom surface and/or the lower bottom surface of the cylinder are bullet-shaped.
The bullet-shaped design facilitates the advancement of the tissue marking needle in the enteroscopy biopsy channel.
Preferably, the luminescent coating is a poly ((di (P-carboxyphenyl) succinate-co-sebacic anhydride) (P (P-dCPS: SA)) coating.
The above luminescent coating can control the degradation rate of the coating between several days and several months by adjusting different Salicylic Acid (SA) ratios.
The luminescent coating can emit blue fluorescence under the excitation of ultraviolet light (330-400 nm), and can emit green fluorescence under the excitation of visible light (450-490 nm).
The luminescent coating enables the tissue marking needle to be quickly identified.
Preferably, the number of hooks is at least 3.
When the quantity of coupler body is 3, 3 coupler body evenly distributed outside the base makes the whole tripod structure that is of tissue marking needle, can firmly fix the base on tissue.
Further preferably, the hook body comprises a first hook body (110), a second hook body (120) and a third hook body (130).
Still further preferably, a first barb (1110) is disposed on the first hook (110), a second barb (1210) is disposed on the second hook (120), and a third barb (1310) is disposed on the third hook (130).
The arrangement of the barbs further enhances the stability of the tissue marking needle fixed on the tissue.
Preferably, the hook material is a water swellable material.
Further preferably, the hook material is gelatin.
The gelatin can expand when meeting water or tissue fluid, and the connection between the base and the tissue is firmer after the hook body is enlarged.
Preferably, the hook body is a straight hook.
Preferably, the hook body is a hook.
The hook body is a straight hook, which is convenient for the pushing and the application of the tissue marking needle.
The hook body is a hook, so that the connection between the base and the tissue is more stable.
The embodiment of the utility model provides a beneficial effect
1. The embodiment of the utility model provides a tissue marking needle, this tissue marking needle includes base and coupler body, wherein is provided with luminous coating on the base, the coupler body sets up with the base outside, links to each other the base with the tissue that needs the mark, when using, through the biopsy pore of intestines mirror, can apply the tissue marking needle to the tissue that needs the mark conveniently, reduced surgeon's operation degree of difficulty, also reduced patient's misery;
2. the tissue marking needle provided by the embodiment of the utility model is made of degradable material, so that the tissue marking needle can be completely degraded in vivo, and the operation is not needed to be carried out again in order to take out the tissue marking needle from the body, thereby solving the problem that the marker needs to be taken out through the operation again in the prior art;
3. the utility model discloses tissue marking needle, base surface are provided with luminous coating, and luminous coating is for gathering ((two (to-carboxylic acid phenyl) succinate-one sebacic anhydride altogether) (P (P-dCPS: SA)) a coating layer, the degradation rate of the coating can be controlled between a few days to a few months by adjusting different Salicylic Acid (SA) ratios, can emit blue fluorescence under the excitation of ultraviolet light (330-400 nm), and under the excitation of visible light (450-490 nm), can emit green fluorescence, can quickly identify and find the tissue marking needle, solves the problems in the prior art, after the biopsy has been placed with the tissue marker, additional marking tools such as radiotracers or radioactive particles must then be placed at the same site, and the repetition increases the problems of the surgical and radiology teams working.
Drawings
FIG. 1 is a schematic view of a tissue marking needle according to example 1.
Fig. 2 is a schematic view of a tissue marking needle according to example 2.
Detailed Description
The following are specific embodiments of the present invention and the technical solutions of the present invention will be further described with reference to the embodiments, but the present invention is not limited to these embodiments.
Example 1
The present example provides a tissue marking needle, as shown in FIG. 1, comprising
The LED lamp comprises a base 10, wherein a luminous coating is arranged on the base 10;
the hook body is arranged outside the base 10 and fixedly connected with the base 10.
The tissue marking needle provided by the embodiment of the utility model is provided with the luminous coating on the base, on one hand, the tissue marking needle plays a role of marking, and can accurately position and mark the tissue part of biopsy; on the other hand, the mark is convenient to find again. The hook may penetrate into tissue for securing the base to the tissue. When in use, the tissue marking needle can be conveniently applied to the tissue to be marked through the biopsy pore canal of the enteroscope, thereby reducing the operation difficulty of a surgeon and the pain of a patient.
The material of the tissue marking needle is degradable material, so that the tissue marking needle can be completely degraded in the body, and the operation for taking the tissue marking needle out of the body is not needed to be carried out again. Solves the problem that the marker needs to be taken out through a secondary operation in the prior art. Degradable materials include Polylactide (PLA), poly (lactide-co-glycolide) (PLGA), polyanhydrides, polyorthoesters, poly (N- (2-hydroxypropyl) methacrylamide), poly (dl-lactide) (DLPLA), poly (l-lactide) (LPLA), Polyglycolide (PGA), Polydioxanone (PDO), poly (glycolide-co-trimethylene carbonate) (PGA-TMC). The degradable material also includes copolymers of one or more of poly (l-lactide-co-glycolide) (PGA-LPLA), poly (dl-lactide-co-glycolide) (PGA-DLPLA), poly (l-lactide-co-dl-lactide) (LPLA-DLPLA), poly (glycolide-co-trimethylene carbonate-co-dioxanone) (PDO-PGA-TMC), and polyarginine.
The base 10 is shaped as a cylinder, and the hook is fixedly disposed on a side surface of the cylinder.
The upper bottom surface and/or the lower bottom surface of the cylinder are bullet-shaped.
The luminescent coating is a poly ((P-carboxyphenyl) succinate-co-sebacic anhydride) (P-dCPS: SA)) coating.
The number of the hook bodies is at least 3. When the quantity of coupler body is 3, 3 coupler body evenly distributed outside the base makes the whole tripod structure that is of tissue marking needle, can firmly fix the base on tissue.
The hook body includes a first hook body 110, a second hook body 120, and a third hook body 130.
The first hook body 110 is provided with a first barb 1110, the second hook body 120 is provided with a second barb 1210, and the third hook body 130 is provided with a third barb 1310. The arrangement of the barbs further enhances the stability of the tissue marking needle fixed on the tissue. The hook body is made of gelatin, the gelatin can expand when meeting water or tissue fluid, and the base is connected with the tissue more firmly after the hook body is enlarged.
In this example, the hook body is a straight hook.
Example 2
The present example provides a tissue marking needle, as shown in FIG. 1, comprising
The LED lamp comprises a base 10, wherein a luminous coating is arranged on the base 10;
the hook body is arranged outside the base 10 and fixedly connected with the base 10.
The tissue marking needle provided by the embodiment of the utility model is provided with the luminous coating on the base, on one hand, the tissue marking needle plays a role of marking, and can accurately position and mark the tissue part of biopsy; on the other hand, the mark is convenient to find again. The hook may penetrate into tissue for securing the base to the tissue. When in use, the tissue marking needle can be conveniently applied to the tissue to be marked through the biopsy pore canal of the enteroscope, thereby reducing the operation difficulty of a surgeon and the pain of a patient.
The material of the tissue marking needle is degradable material, so that the tissue marking needle can be completely degraded in the body, and the operation for taking the tissue marking needle out of the body is not needed to be carried out again. Solves the problem that the marker needs to be taken out through a secondary operation in the prior art. Degradable materials include Polylactide (PLA), poly (lactide-co-glycolide) (PLGA), polyanhydrides, polyorthoesters, poly (N- (2-hydroxypropyl) methacrylamide), poly (dl-lactide) (DLPLA), poly (l-lactide) (LPLA), Polyglycolide (PGA), Polydioxanone (PDO), poly (glycolide-co-trimethylene carbonate) (PGA-TMC). The degradable material also includes copolymers of one or more of poly (l-lactide-co-glycolide) (PGA-LPLA), poly (dl-lactide-co-glycolide) (PGA-DLPLA), poly (l-lactide-co-dl-lactide) (LPLA-DLPLA), poly (glycolide-co-trimethylene carbonate-co-dioxanone) (PDO-PGA-TMC), and polyarginine.
The base 10 is shaped as a cylinder, and the hook is fixedly disposed on a side surface of the cylinder.
The upper bottom surface and/or the lower bottom surface of the cylinder are bullet-shaped.
The luminescent coating is a poly ((P-carboxyphenyl) succinate-co-sebacic anhydride) (P-dCPS: SA)) coating.
The number of the hook bodies is at least 3. When the quantity of coupler body is 3, 3 coupler body evenly distributed outside the base makes the whole tripod structure that is of tissue marking needle, can firmly fix the base on tissue.
The hook body includes a first hook body 110, a second hook body 120, and a third hook body 130.
The first hook body 110 is provided with a first barb 1110, the second hook body 120 is provided with a second barb 1210, and the third hook body 130 is provided with a third barb 1310. The arrangement of the barbs further enhances the stability of the tissue marking needle fixed on the tissue. The hook body is made of gelatin, the gelatin can expand when meeting water or tissue fluid, and the base is connected with the tissue more firmly after the hook body is enlarged.
In this example, the hook body is a hook.
Example 3
The embodiment provides a use method of a tissue marking needle, which comprises the following specific steps:
in use, the tissue marking needle is applied to a tissue site to be marked through a biopsy channel of the enteroscope.
The biopsy channel of the enteroscope is a common channel for operations such as biopsy tissue taking, medicine injection, electric polyp excision and the like, and a tissue marking needle can be conveniently applied to a tissue part needing to be marked through the channel. The upper bottom surface of the tissue marking needle base, i.e. the surface connected with the biopsy channel of the enteroscope, can be directly designed to be of a size matched with the biopsy hole, thereby being convenient for directly applying the tissue marking needle through the biopsy channel. In addition, a connecting piece can be additionally designed, and the connecting piece is used for connecting the base of the tissue marking and the biopsy hole of the enteroscope, so that the tissue marking needle can be conveniently applied.

Claims (7)

1. A tissue marking needle, comprising
A base (10), wherein a luminous coating is arranged on the base (10);
the hook body is arranged outside the base (10) and fixedly connected with the base (10).
2. The tissue marking needle according to claim 1, characterized in that the base (10) is shaped as a cylinder, the hook being fixedly arranged on a side of the cylinder.
3. The tissue marking needle of claim 2 wherein the upper and/or lower bottom surface of the cylinder is bullet-shaped.
4. The tissue marking needle according to claim 1, wherein the number of hooks is at least 3, the hooks comprising a first hook (110), a second hook (120) and a third hook (130).
5. The tissue marking needle of claim 4, wherein the first hook body (110) is provided with a first barb (1110), the second hook body (120) is provided with a second barb (1210), and the third hook body (130) is provided with a third barb (1310).
6. The tissue marking needle of claim 1 wherein the hook body is a straight hook.
7. The tissue marking needle of claim 1, wherein the hook body is a hook.
CN201921620809.9U 2019-09-26 2019-09-26 Tissue marking needle Active CN211750128U (en)

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CN201921620809.9U CN211750128U (en) 2019-09-26 2019-09-26 Tissue marking needle

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Application Number Priority Date Filing Date Title
CN201921620809.9U CN211750128U (en) 2019-09-26 2019-09-26 Tissue marking needle

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CN211750128U true CN211750128U (en) 2020-10-27

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110584796A (en) * 2019-09-26 2019-12-20 中南大学湘雅医院 Tissue marking needle

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110584796A (en) * 2019-09-26 2019-12-20 中南大学湘雅医院 Tissue marking needle

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