CN211718137U - Multi-slide scanning system - Google Patents
Multi-slide scanning system Download PDFInfo
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- CN211718137U CN211718137U CN202020241204.5U CN202020241204U CN211718137U CN 211718137 U CN211718137 U CN 211718137U CN 202020241204 U CN202020241204 U CN 202020241204U CN 211718137 U CN211718137 U CN 211718137U
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Abstract
The utility model provides a multi-disc slide scanning system, include: the slide bin unit is used for storing slides and is provided with a plurality of mutually separated containing cavities, each containing cavity is used for correspondingly containing one bin box, each bin box is provided with a plurality of slide containing grids, and each slide containing grid is used for correspondingly containing one slide; the slide bearing unit is used for bearing a slide to scan and comprises an object stage, wherein two slide bearing positions are arranged on the object stage in parallel and can bear two slides simultaneously; a slide scanning unit for scanning a slide placed on the stage; the slide transferring unit is used for transferring the slide between the slide bin unit and the object stage and comprises a clamping claw module used for grabbing the slide; and the clamping jaw displacement module is used for driving the clamping jaw module to displace. The slide scanning efficiency can be greatly improved.
Description
Technical Field
The utility model relates to an auxiliary system for clinical diagnosis especially involves multi-disc slide scanning system.
Background
The slide scanning system is widely applied to the diagnosis of pathology, hematology, cytology and the like, and is widely applied to clinical diagnosis. Slide scanners are still under development, and there are currently single slide scanners, multi-slide scanners. Due to technical limitation, a plurality of slide scanning instruments on the market are still arranged in a single scanning instrument, the capacity of the single scanning instrument is used for loading a plurality of slides at one time, and after the slides are sequentially and completely scanned, the slides are manually loaded.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model lies in, to the above-mentioned defect of prior art, provide a multi-disc slide scanning system, can promote slide scanning efficiency greatly.
The utility model provides a technical scheme that its technical problem adopted is: a multi-slide scanning system is provided, comprising: the slide bin unit is used for storing slides and is provided with a plurality of mutually separated containing cavities, each containing cavity is used for correspondingly containing one bin box, each bin box is provided with a plurality of slide containing grids, and each slide containing grid is used for correspondingly containing one slide;
the slide bearing unit is used for bearing a slide to scan and comprises an object stage, wherein two slide bearing positions are arranged on the object stage in parallel and can bear two slides simultaneously;
a slide scanning unit for scanning a slide placed on the stage; and
the slide transferring unit is used for transferring the slide between the slide bin unit and the object stage and comprises a clamping claw module used for grabbing the slide; and the clamping jaw displacement module is used for driving the clamping jaw module to displace.
In some embodiments, the slide magazine unit is provided with a sensor corresponding to each of the receiving cavities for sensing whether a magazine is present in the receiving cavity.
In some embodiments, the gripper module is provided with a sensor for sensing the slide.
In some embodiments, the sensor is a laser sensor for sensing the upper and lower side edges of the slide.
In some embodiments, the jaw module includes two jaws for gripping both sides of the slide from both sides; and a servo motor for driving the two clamping jaws to open and close.
In some embodiments, the plurality of accommodating cavities are arranged in upper and lower rows, and each row is provided with a plurality of accommodating cavities in parallel; a plurality of slide containing grids of the bin box are horizontally arranged and are arranged up and down.
In some embodiments, the slide scanning unit is provided with two side-by-side objectives at different magnifications for scanning the same slide on the stage.
In some embodiments, the two objective lenses are controlled to be displaceable in the X-axis direction and the Z-axis direction.
In some embodiments, the stage is controlled to be displaceable in the X-axis direction and the Y-axis direction.
In some embodiments, the jaw displacement module comprises: the X-axis displacement driving mechanism is used for driving the clamping jaw module to displace in the X-axis direction; the Y-axis displacement driving mechanism is used for driving the clamping jaw module to displace in the Y-axis direction; and the Z-axis displacement driving mechanism is used for driving the clamping jaw module to displace in the Z-axis direction.
The utility model has the advantages that the slide bin unit, the slide bearing unit, the slide scanning unit and the slide transferring unit are organically combined together, and the slide bin unit can hold a large number of slides, so that unattended operation can be realized for a long time, and the slide scanning efficiency can be greatly improved; in addition, two slide bearing positions are arranged on one objective table, and during the period that one slide is positioned on the objective table for scanning, the slide transferring unit can simultaneously transfer the other slide between the slide chamber unit and the slide bearing unit, so that the parallel processing of the scanning of one slide and the replacement and transfer of the other slide can be realized, the slide replacement time of the scanning processing of the slide can be saved, and the slide scanning efficiency can be further improved.
Drawings
The invention will be further explained with reference to the drawings and examples, wherein:
FIG. 1 is a perspective view of a multi-slide scanning system according to the present invention.
Figure 2 is a perspective view of another perspective of the multi-slide scanning system of the present invention.
FIG. 3 is a front view of the multi-slide scanning system of the present invention.
FIG. 4 is a schematic top view of the multi-slide scanning system of the present invention.
Fig. 5 is a schematic side view of the multi-slide scanning system of the present invention.
Wherein the reference numerals are as follows: 10 scanning system 1 slide magazine unit 15 magazine 2 slide carrier unit 21 stage 211 first slide carrier position 212 second slide carrier position 29 window 3 slide scanning unit 31 first objective lens 32 second objective lens 39 rack 4 slide carrier unit 41 jaw module 411 jaw module 42 jaw displacement module 421X axis displacement drive mechanism 422Y axis displacement drive mechanism 423Z axis displacement drive mechanism 9 slides.
Detailed Description
The preferred embodiments of the present invention will now be described in detail with reference to the accompanying drawings.
Referring to fig. 1-5, fig. 1 is a schematic perspective view of a multi-slide scanning system according to the present invention. Figure 2 is a perspective view of another perspective of the multi-slide scanning system of the present invention. FIG. 3 is a front view of the multi-slide scanning system of the present invention. FIG. 4 is a schematic top view of the multi-slide scanning system of the present invention. Fig. 5 is a schematic side view of the multi-slide scanning system of the present invention. The utility model provides a multi-disc slide scanning system 10, it includes: a slide magazine unit 1, a slide carrying unit 2, a slide scanning unit 3, a slide transfer unit 4, and an electronic control unit (not shown).
The slide magazine unit 1 is used to store slides 9, both to be scanned and already scanned. In the present embodiment, the slide magazine unit 1 is provided with eight receiving cavities separated from each other, each receiving cavity being adapted to receive one magazine 15. The eight accommodating cavities are arranged into an upper row and a lower row, and four accommodating cavities are arranged in parallel in each row. Each magazine 15 is provided with thirty slide receiving compartments, which are horizontally arranged in an up-down arrangement. Each slide housing compartment has two card slots facing each other from left to right, and one slide 9 can be inserted into/pulled out of the corresponding slide housing compartment by virtue of the engagement of both side edges thereof with the two card slots.
It is understood that the slide magazine unit 1 of the present embodiment can accommodate two hundred and forty slide sheets 9 at the same time at the maximum. The number of slides 9 simultaneously received by the slide magazine unit 1 can be flexibly adjusted according to the requirements of practical application. For example, eight receiving cavities of the slide magazine unit 1 are each provided with a magazine 15, wherein six magazines 15 are empty, i.e. not loaded with any slides 9. The magazine 15, located in the rightmost receiving cavity of the upper row, has a slide 9 in the topmost slide receiving bay. The magazine 15, located in the rightmost receiving cavity of the lower row, has a slide 9 in the lowermost slide receiving bay.
It is worth mentioning that, in the eight accommodating cavities, eight sensors (not shown in the figure) are correspondingly arranged in one-to-one correspondence according to the positions of the eight bins 15, and when the bins 15 are placed in the accommodating cavities, the sensors can detect that the bins 15 are currently placed in the accommodating cavities; similarly, when no magazine 15 is placed in the receiving cavity, the sensor can detect that no magazine 15 is currently placed in the receiving cavity, and the sensor feeds back the detected signal to the electronic control unit (e.g., control card).
And the slide bearing unit 2 is used for bearing the slide 9 to carry out scanning. Which comprises a stage 21, the stage 21 is provided with a window 29 arranged along the X-axis, two slide carrying positions 211, 212 are arranged in parallel on the window 29, and two slides 9 can be carried simultaneously (see fig. 1 and 4, which show two slides 9 carried on the two slide carrying positions 211, 212; see fig. 2, which shows one slide 9 carried on the second slide carrying position 212).
In the present embodiment, this stage 21 is controlled to be displaceable in the X-axis and Y-axis directions. Specifically, the stage 21 is displaced along the Y axis to enter/exit the scanning area; after entering the scanning area, the stage 21 is displaced along the X-axis to selectively move the slide 9 on the first slide holding position 211/the second slide holding position 212 to/from the scanning position.
A slide scanning unit 3 for scanning the slide 9 placed on the stage 21 of the slide bearing unit 2. Two parallel objective lenses 31, 32 with different magnifications are provided, the two objective lenses 31, 32 being used to scan the same slide 9 on the stage 21. For example, only one of the two objective lenses 31, 32 may be selected for scanning the slide 9; it is also possible to first scan the slide 9 with the first objective lens 31 and then to scan the slide 9 with the second objective lens 32. For example, first, the user wants to default to a 20 times objective (assuming the first objective 31) scan; then, the user wants to see the 40-fold scanning of the objective lens (assuming that the second objective lens 32 is used), and can switch the objective lens to perform the 40-fold scanning by seeing how the effect is.
In the present embodiment, the first objective lens 31 and the second objective lens 32 are arranged in the X-axis direction. The first objective lens 31 has a small magnification and the second objective lens 32 has a large magnification. The first objective lens 31 and the second objective lens 32 are located on the same carriage 39, and this carriage 39 is controlled to be displaceable in the X-axis direction and the Z-axis direction. Specifically, the carriage 39 is displaced in the X-axis direction, and switching of the objective lens when the slide 9 is scanned with the first objective lens 31 and/or the second objective lens 32 can be realized; the holder 39 is displaced in the Z-axis direction, and focusing when the first objective lens 31/the second objective lens 32 scans the slide 9 can be achieved.
A slide transfer unit 4 for transferring the slide glass 9 between the slide magazine unit 1 and the stage 21 of the slide bearing unit 2. It includes: a gripper block 41 for gripping the slide 9; and a jaw displacement module 42 for driving the jaw module 41 to be displaced. In the present embodiment, the gripper module 41 is provided with a sensor for sensing the slide 9, for example: laser sensors for sensing the upper and lower side edges of the slide 9.
It is worth mentioning that the jaw module 41 comprises two jaws 411 (see fig. 4) for gripping both sides of the slide 9 from both sides, the two jaws 411 being oppositely disposed, being able to close to each other and open away from each other; and a servo motor (not shown) for driving the two jaws 411 to open and close. In operation, the servo motor provides clamping force to the two clamping jaws 411, and when the two clamping jaws 411 clamp the slide 9, the servo motor can stop continuously applying force after sensing the acting force of the slide 9 to the two clamping jaws 411, so as to clamp the slide 9. In addition, a set distance when the slide 9 is not clamped is preset between the two clamping jaws 411, and the set distance is smaller than the width of the slide 9 (namely, the distance between the two opposite sides of the slide 9) to help judge whether the clamping jaw module 41 clamps the slide 9.
The jaw displacement module 42 can drive the jaw module 41 to displace in a three-dimensional space formed by X-Y-Z axes. Specifically, the jaw displacement module 42 includes: an X-axis displacement driving mechanism 421 for driving the jaw module 41 to displace in the X-axis direction; a Y-axis displacement driving mechanism 422 for driving the jaw module 41 to displace in the Y-axis direction; and a Z-axis displacement driving mechanism 423 for driving the jaw module 41 to be displaced in the Z-axis direction.
The working principle of the multi-sheet slide scanning system 10 of the present invention substantially includes:
first, a magazine door (not shown) of the slide magazine unit 1 is opened, and a slide 9 to be scanned is put into a magazine 15; then, placing a plurality of bin boxes 15 into a plurality of accommodating cavities of the slide bin unit 1, and closing bin doors after placing;
the electronic control unit then controls the action of the slide transfer unit 4, the gripper module 41 moves to the detected magazine 15, scans it from top to bottom (by means of the sensors mounted on the gripper module 41), scans the magazine 15 from top to bottom twice (the first falling edge signal being active for determining the position of the upper edge of the slide 9 and the second rising edge signal being active for determining the position of the lower edge of the slide 9), and from this, the electronic control unit can determine the number and position of slides 9 in the magazine 15, and scan all the magazines 15 mounted in the slide magazine unit 1 in turn, and the electronic control unit can determine the position and number of all the slides 9 to be scanned in the slide magazine unit 1.
Then, the electronic control unit can control the slide transfer unit 4 to pick up the slide 9 on the slide magazine unit 1 and send the slide to the slide scanning unit 3 for scanning in the set sequence.
It is worth mentioning that while slide scanning is in progress, opening of the magazine door of the slide magazine unit 1 is prohibited to prevent the user from taking away the magazine 15 that is loaded with slides 9 being scanned; only after the automatic stop and the manual cancel of the scanning are completed, the slide transfer unit 4 clamps the slide 9 on the slide bearing unit 2 and puts the slide back to the original position (i.e., a certain slide accommodating grid in a certain compartment 15 on the slide compartment unit 1), and then the compartment door of the slide compartment unit 1 can be opened for the operations such as slide replacement.
It will be appreciated that the multi-slide scanning system 10 of the present invention employs a gripper module 41 in cooperation with a stage 21 having two slide receiving locations 211, 212, such that slides 9 can be flexibly placed on and removed from the two slide receiving locations 211, 212.
For example, first, the clamping jaw module 41 moves to the first magazine 15 of the slide magazine unit 1 to clamp the first slide 9 under the driving of the clamping jaw displacement module 42; then, the gripper module 41 is driven by the gripper displacement module 42 to place the first slide 9 at the first slide receiving position 211 of the slide receiving unit 2, and at this time, in order to avoid accidental collision, the stage 21 is controlled to move outward (i.e., downward to the left in the Y direction in fig. 1), away from the scanning area (i.e., downward to the Z direction in fig. 1 and 2 of the first objective lens 31 and the second objective lens 32), and to go to an empty area to wait for the first slide 9 to be placed; then, the stage 21 is controlled to move inward (i.e., upward and rightward in the Y direction in fig. 1) to a position under the recognition camera of the slide scanning unit 3, and a scanning area is determined based on the captured image; then, the two objective lenses 31, 32 are moved to the scanning positions, and scanning is performed according to the received instructions (for example, the slide 9 is scanned in a line-by-line S-shaped scanning mode), and images are acquired.
During the positioning scanning of the first slide 9, the claw module 41 is driven by the claw displacement module 42 to move to the position of the second slide 9 of the slide chamber unit 1 to clamp the slide 9; then, the scanning of the preceding first slide 9 is waited for to be completed at the set area. When the scanning of the first slide 9 is completed, the stage 21 is controlled to move out of the scanning area to await the next action by the gripper module 41; at this time, the gripper module 41 places the second slide 9 clamped thereon on the second slide bearing position 212; then comes to the first slide carrying position 211, automatically picks up the scanned first slide 9, and returns it to its initial position in the slide chamber unit 1; then, gripping of the third slide 9 is continued, at which time the stage 21 has been controlled to move back to the scanning area and the second slide 9 on the second slide support 212 is being subjected to scout scan to acquire an image, and the gripper module 41 waits for the scanning of the preceding second slide 9 to be completed at the set area. When the scanning of the second slide 9 in front is completed, the stage 21 is controlled to move out of the scanning area, waiting for the next action of the gripper module 41; at this time, the gripper module 41 will place the third slide 9 on the first slide-holding position 211 and then move to the second slide-holding position 212, automatically pick up the second slide 9 after the scanning is completed, and return it to its initial position in the slide magazine unit 1; this is repeated until all the slides 9 in the magazine unit 1 have been scanned.
The utility model has the advantages that the slide bin unit 1, the slide bearing unit 2, the slide scanning unit 3 and the slide transferring unit 4 are organically combined together, and the slide bin unit 1 can contain a large number of slides 9 (up to two hundred forty slides 9, namely every two hundred forty slides 9 need to be alternated), so that unattended operation can be realized for a long time during scanning, and the slide scanning efficiency can be greatly improved; moreover, by providing two slide bearing positions 211 and 212 on one stage 21, the slide transfer unit 4 can simultaneously perform transfer processing of another slide 9 between the slide magazine unit 1 and the slide bearing unit 2 while one slide 9 is on the stage 21 for scanning, so that parallel processing of scanning of one slide 9 and replacement and transfer of another slide 9 can be realized, replacement time of scanning processing of the slide 9 can be saved, and slide scanning efficiency can be greatly improved.
It should be understood that the above embodiments are only used for illustrating the technical solutions of the present invention, and not for limiting the same, and those skilled in the art can modify the technical solutions described in the above embodiments, or make equivalent substitutions for some technical features; and that such modifications and substitutions are intended to be included within the scope of the appended claims.
Claims (10)
1. A multi-slide scanning system, comprising:
the slide bin unit is used for storing slides and is provided with a plurality of mutually separated containing cavities, each containing cavity is used for correspondingly containing one bin box, each bin box is provided with a plurality of slide containing grids, and each slide containing grid is used for correspondingly containing one slide;
the slide bearing unit is used for bearing a slide to scan and comprises an object stage, wherein two slide bearing positions are arranged on the object stage in parallel and can bear two slides simultaneously;
a slide scanning unit for scanning a slide placed on the stage; and
the slide transferring unit is used for transferring the slide between the slide bin unit and the object stage and comprises a clamping claw module used for grabbing the slide; and the clamping jaw displacement module is used for driving the clamping jaw module to displace.
2. The multi-slide scanning system of claim 1, wherein the slide magazine unit includes a sensor corresponding to each of the receiving cavities for sensing whether a magazine is present in the receiving cavity.
3. The multi-slide scanning system of claim 1, wherein the gripper module is provided with a sensor for sensing the slide.
4. A multi-slide scanning system as claimed in claim 3, wherein the sensor is a laser sensor for sensing the upper and lower side edges of the slide.
5. The multi-slide scanning system of claim 1, wherein the gripper module includes two jaws for gripping both sides of the slide from both sides; and a servo motor for driving the two clamping jaws to open and close.
6. The multi-slide scanning system of claim 1, wherein the plurality of receiving cavities are arranged in two rows, one above the other, each row having a plurality of receiving cavities arranged in parallel; a plurality of slide containing grids of the bin box are horizontally arranged and are arranged up and down.
7. The multi-slide scanning system of claim 1, wherein the slide scanning unit has two side-by-side objectives at different magnifications for scanning the same slide on the stage.
8. The multi-slide scanning system of claim 7, wherein the two objective lenses are controlled to be displaceable in an X-axis direction and a Z-axis direction.
9. The multi-slide scanning system of claim 1, wherein the stage is controllably displaceable in an X-axis direction and a Y-axis direction.
10. The multi-slide scanning system of claim 1, wherein the finger displacement module comprises: the X-axis displacement driving mechanism is used for driving the clamping jaw module to displace in the X-axis direction; the Y-axis displacement driving mechanism is used for driving the clamping jaw module to displace in the Y-axis direction; and the Z-axis displacement driving mechanism is used for driving the clamping jaw module to displace in the Z-axis direction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020241204.5U CN211718137U (en) | 2020-03-02 | 2020-03-02 | Multi-slide scanning system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202020241204.5U CN211718137U (en) | 2020-03-02 | 2020-03-02 | Multi-slide scanning system |
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| Publication Number | Publication Date |
|---|---|
| CN211718137U true CN211718137U (en) | 2020-10-20 |
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| CN202020241204.5U Active CN211718137U (en) | 2020-03-02 | 2020-03-02 | Multi-slide scanning system |
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| CN (1) | CN211718137U (en) |
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- 2020-03-02 CN CN202020241204.5U patent/CN211718137U/en active Active
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