CN211528005U - Real-time fixing device after frozen pathological tissue draws materials - Google Patents
Real-time fixing device after frozen pathological tissue draws materials Download PDFInfo
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- CN211528005U CN211528005U CN201922431119.5U CN201922431119U CN211528005U CN 211528005 U CN211528005 U CN 211528005U CN 201922431119 U CN201922431119 U CN 201922431119U CN 211528005 U CN211528005 U CN 211528005U
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Abstract
A real-time fixing device for a frozen pathological tissue after material drawing belongs to the technical field of pathological tissue fixing devices and solves the technical problems that the fixing process of the frozen tissue after material drawing is disordered and the health of an operator is influenced by repeated contact with a fixing liquid. The solution is as follows: the inner part of the barrel body is provided with an embedding and fixing cavity, the side walls of the barrel body at the front side and the rear side of the embedding and fixing cavity are provided with a fixed liquid storage cavity, the fixed liquid storage cavities are communicated with the embedding and fixing cavity through fixed liquid injection holes, and the side wall of the embedding and fixing cavity at each fixed liquid injection hole is provided with a sealing device; two hollow guide pillars are symmetrically arranged in the side walls of the barrel bodies at the left side and the right side of the embedding fixing cavity, a spring is arranged in each hollow guide pillar, and a guide groove is arranged on the side wall of each hollow guide pillar along the axis direction of the hollow guide pillar. The utility model discloses can fix the frozen pathological tissue after drawing materials in order fast, save follow-up tissue piece arrangement time, also can reduce the contact number of times of operating personnel hand and stationary liquid.
Description
Technical Field
The utility model belongs to the technical field of pathological tissue fixing device, concretely relates to real-time fixing device after freezing pathological tissue draws materials.
Background
After the operation, the human tissue specimen needs to be sent to a pathology department, and after the materials are taken, fixed, dehydrated and further stained and sliced by a pathologist, the pathological tissue specimen can be observed under a pathological microscope to make final diagnosis, so that a clinical further treatment scheme is guided. The qualified tissue pretreatment process is especially important for accurate diagnosis of subsequent materials selection and fixation, and if the tissue is not fixed enough, the morphological structure of tissue cells and the state of biomacromolecules such as nucleic acid, protein and the like are abnormal, so that the pathological observation and the quality of molecular pathological experiments are directly influenced, and misdiagnosis can be caused in severe cases. The most commonly used fixing solution in clinic at present is 4% neutral formalin which is widely used in the pathology department at home and abroad due to good tissue fixing effect, but formalin has pungent smell and has adverse toxic action on human bodies after long-term contact.
At present, when a domestic pathology department fixes a frozen tissue after the frozen tissue is taken for operation, in order to ensure that a specimen can be fixed in time, a large glass jar is usually used for soaking a fixing solution, and a tissue block is immediately put into the glass jar after the frozen tissue is taken; when the subsequent tissue needs to be dehydrated and embedded, the tissue is fished out from the cylinder, arranged and put into a dehydrator for dehydration. However, the tissue blocks are in a messy soaking state in the glass jar, the follow-up technicians need to fish the tissue blocks out by hands and sort the tissue blocks one by one, frequent contact with formalin solution is needed for repeated work every day, even if gloves are arranged, skin contact cannot be completely avoided, and certain hidden danger exists for health. And the process of organizing block reordering also consumes a certain time, which affects the whole working progress.
SUMMERY OF THE UTILITY MODEL
The utility model discloses an inventive purpose: in order to overcome prior art's not enough, solve the operation and freeze the tissue and draw materials after the fixed process mixed and disorderly, work efficiency is low, fixed in-process operating personnel relapse with the technical problem that stationary liquid contact influences operating personnel is healthy, the utility model provides a freeze real-time fixing device after pathological tissue draws materials.
The utility model discloses a following technical scheme realizes.
The utility model provides a real-time fixing device after freezing pathological tissue draws materials, it includes spring, tray and is used for placing the staving of freezing pathological tissue embedding box, wherein:
the device comprises a barrel body, a cover body, a material taking window, a material taking door and a material taking door, wherein the cover body covers an opening position at the upper end of the barrel body, the core part of the barrel body is provided with an embedding and fixing cavity, the embedding and fixing cavity is arranged along the axis direction, a plurality of spring top beads are arranged on the side wall of the embedding and fixing cavity, the lower part of the side wall of the barrel body is provided with the material taking window, the material taking window is communicated;
two fixing liquid storage cavities are symmetrically arranged in the side walls of the barrel bodies on the front side and the rear side of the embedding and fixing cavity, a plurality of fixing liquid injection holes are formed in the side wall of the fixing liquid storage cavity close to one side of the embedding and fixing cavity at equal intervals along the vertical direction, and fixing liquid flows into the embedding and fixing cavity from the fixing liquid storage cavities through the fixing liquid injection holes; a sealing device is arranged at each position of the fixing liquid injection hole on the side wall of the embedding fixing cavity and comprises a magnetic limiting rod, a magnet, a sealing rolling door and a recovery scroll, the magnet is embedded into the upper edge of the fixing liquid injection hole, a groove for fixing the magnetic limiting rod is arranged on the outer side surface of the magnet, the magnetic limiting rod is adsorbed on the magnet, one end of the sealing rolling door is fixed on the magnetic limiting rod, the other end of the sealing rolling door is fixed on the recovery scroll, and the recovery scroll is arranged in the lower edge of the fixing liquid injection hole;
two hollow guide columns are symmetrically arranged in the side walls of the barrel bodies at the left side and the right side of the embedding and fixing cavity, a spring is arranged in each hollow guide column, and guide grooves are formed in the side walls of the hollow guide columns along the axial direction of the hollow guide columns; the tray is square and is arranged in the embedding fixed cavity, the tray and the inner wall of the embedding fixed cavity are in transition fit, the side walls of two sides of the tray are respectively provided with a baffle at the position corresponding to the guide groove, the baffles are arranged above the spring, and the baffles slide downwards along the guide groove to extrude the spring so as to enable the spring to be in a compressed state; be provided with the tray slide rail on the upper surface of tray, the axis direction of tray slide rail with it is parallel to each other to get material window length direction, and a plurality of embedding boxes from top to bottom stack in proper order on the tray in the fixed chamber of embedding, are provided with the embedding box slide rail on the top surface of embedding box, are provided with on the bottom surface of embedding box with embedding box slide rail or tray slide rail matched with embedding box spout.
Furthermore, a seam allowance matched with the embedding fixing cavity is arranged on the lower end face of the cover body.
Furthermore, two get the material window coaxial setting in the embedding fixed cavity front and back both sides staving lateral wall's lower part, one side is got the material window and is pushed away the embedding box, and the opposite side is got the material window and is pulled the embedding box, and the embedding box is taken out from the staving along the tray slide rail.
Further, when the magnetic limiting rod is adsorbed on the magnet, the outermost layer of the sealing rolling door is arranged in the embedding fixing cavity.
A method for fixing frozen pathological tissues by a real-time fixing device after the materials of the frozen pathological tissues are taken comprises the following steps:
s1, the initial state of the fixing device, namely the state that the embedding box is not placed in the barrel: the spring is in a free state, the baffle is positioned at the uppermost end of the guide groove, the tray is positioned above the fixed liquid injection holes at the uppermost end, the sealing device at the position of each fixed liquid injection hole is completely sealed, the cover body is opened, and the fixed liquid storage cavity is filled with the fixed liquid;
s2, fixing the tissue after the tissue is drawn, namely putting the tissue into the barrel together with the embedding box after the tissue is drawn:
s21, opening the cover body to enable the embedding box to be installed above the tray, enabling the embedding box sliding grooves to be correspondingly installed on the tray sliding rails, and covering the cover body above the barrel body; the embedding box enables the baffles on the two sides of the tray to extrude the springs by pressing the tray, the baffles slide downwards along the guide groove for a distance of the height of the embedding box, and the spring ejecting balls eject the embedding box on the tray to be just clamped at the lower edge position of the fixing liquid injection hole; in the process of descending the tray, the magnetic limiting rod corresponding to the position of the fixing liquid injection hole slides out of the groove formed in the magnet, the sealing rolling door drives the magnetic limiting rod to roll back to the recovery rolling shaft, the sealing rolling door at the position of the fixing liquid injection hole is opened, the fixing liquid storage cavity is communicated with the embedding fixing cavity through the fixing liquid injection hole, and the fixing liquid flows into the embedding box to fix tissues in the embedding box;
s22, repeating the step S21, sequentially placing the embedding boxes to be fixed into the embedding fixing cavity, sequentially stacking the embedding boxes on the tray along the vertical direction, gradually opening all sealing devices in the descending process of the tray, continuously flowing out the fixing liquid in the fixing liquid storage cavity, immersing all the embedding boxes in the embedding fixing cavity in the fixing liquid, and fixing after the frozen pathological tissue is obtained;
s3, taking out the fixed embedding box: when the tray moves to the final position of the lower stroke, the embedding box firstly fixed by the fixing liquid is taken out along the tray slide rail through the material taking window;
s4, after the fixing device is used, the tool is used to stretch into the embedding fixing cavity, the magnetic limiting rod is sucked into the groove arranged on the magnet again, the curled sealing rolling door is unfolded, the sealing device is closed, the steps S1-S3 are repeated, and the fixing device is recycled.
Compared with the prior art, the beneficial effects of the utility model are that:
the utility model discloses can fix the frozen pathological tissue after drawing materials in order fast, make the separation freeze the fixed more timely, the standardization of pathological tissue, this device goes on according to the sample order of drawing materials to the fixed of tissue simultaneously, saves follow-up tissue piece arrangement time, also can reduce the contact number of times of operating personnel hand and stationary liquid (formalin solution, poisonous liquid).
Drawings
Fig. 1 is the half-section structure schematic diagram of the front view of the utility model.
Fig. 2 is a cross-sectional view taken along plane a-a of fig. 1.
Fig. 3 is a schematic view of a partially enlarged cross-sectional structure of the sealing rolling door at the position of the stationary liquid injection hole in a closed state.
Fig. 4 is a schematic view of a partially enlarged cross-sectional structure of the position of the stationary liquid injection hole when the sealing rolling door is in an opened state.
Fig. 5 is a schematic side view of the embedding cassette.
In the figure, 1 is the staving, 2 is hollow guide pillar, 3 is the spring, 4 is the baffle, 5 is the lid, 6 is the tray, 7 is the stationary liquid injection hole, 8 is stationary liquid stock solution chamber, 9 is the fixed chamber of embedding, 10 is spring top pearl, 11 is for getting the material window, 12 is the guide way, 13 is the magnetism gag lever post, 14 is the magnet, 15 is for sealing the roll-up door, 16 is for retrieving the spool, 17 is the tray slide rail, 18 is the embedding box, 181 is the embedding box slide rail, 182 is the embedding box spout.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples.
Fig. 1 and 5 show a real-time frozen pathological tissue fixation device after sampling material, which comprises a spring, a tray 6 and a barrel body 1 for placing a frozen pathological tissue embedding box, wherein:
the cover body 5 is covered at the opening position of the upper end of the barrel body 1, the core part of the barrel body 1 is provided with an embedding fixing cavity 9, the embedding fixing cavity 9 is arranged along the axis direction, the side wall of the embedding fixing cavity 9 is provided with a plurality of spring top beads 10, the lower part of the side wall of the barrel body 1 is provided with a material taking window 11, the material taking window 11 is communicated with the bottom of the embedding fixing cavity 9, and a material taking door is arranged at the material taking window 11;
two fixing liquid storage cavities 8 are symmetrically arranged in the side walls of the barrel bodies 1 on the front side and the rear side of the embedding and fixing cavity 9, a plurality of fixing liquid injection holes 7 are formed in the side wall of the fixing liquid storage cavity 8 close to one side of the embedding and fixing cavity 9 at equal intervals along the vertical direction, and fixing liquid flows into the embedding and fixing cavity 9 from the fixing liquid storage cavities 8 through the fixing liquid injection holes 7; a sealing device is arranged at each position of the fixing liquid injection hole 7 on the side wall of the embedding fixing cavity 9, the sealing device comprises a magnetic limiting rod 13, a magnet 14, a sealing rolling door 15 and a recovery scroll 16, the magnet 14 is embedded into the upper edge of the fixing liquid injection hole 7, a groove for fixing the magnetic limiting rod 13 is arranged on the outer side surface of the magnet 14, the magnetic limiting rod 13 is adsorbed on the magnet 14, one end of the sealing rolling door 15 is fixed on the magnetic limiting rod 13, the other end of the sealing rolling door 15 is fixed on the recovery scroll 16, and the recovery scroll 16 is arranged in the lower edge of the fixing liquid injection hole 7;
two hollow guide pillars 2 are symmetrically arranged in the side walls of the barrel bodies 1 at the left side and the right side of the embedding and fixing cavity 9, a spring 3 is arranged in each hollow guide pillar 2, and a guide groove 12 is arranged on the side wall of each hollow guide pillar 2 along the axial direction of the hollow guide pillar 2; the tray 6 is square, the tray 6 is installed in the embedding fixed cavity 9, the tray 6 is in transition fit with the inner wall of the embedding fixed cavity 9, the baffle plates 4 are respectively arranged on the side walls of the two sides of the tray 6 corresponding to the positions of the guide grooves 12, the baffle plates 4 are arranged above the springs 3, and the baffle plates 4 slide downwards along the guide grooves 12 to extrude the springs 3, so that the springs 3 are in a compressed state; be provided with tray slide rail 17 on the upper surface of tray 6, tray slide rail 17's axis direction with it is parallel to each other to get 11 length direction of material window, and a plurality of embedding boxes 18 stack on tray 6 from top to bottom in proper order in embedding fixed chamber 9, are provided with embedding box slide rail 181 on the top surface of embedding box 18, are provided with on the bottom surface of embedding box 18 with embedding box slide rail 181 or tray slide rail 17 matched with embedding box spout 182.
Furthermore, a spigot matched with the embedding fixing cavity 9 is arranged on the lower end face of the cover body 5.
Further, two material taking windows 11 are coaxially arranged at the lower parts of the side walls of the barrel bodies 1 on the front side and the rear side of the embedding fixing cavity 9, one side of the material taking window 11 pushes the embedding box 18, the other side of the material taking window 11 pulls the embedding box 18, and the embedding box 18 is taken out of the barrel body 1 along the tray slide rail 17.
Further, when the magnetic limiting rod 13 is attached to the magnet 14, the outermost sealing rolling door 15 is disposed in the embedding fixing cavity 9.
The utility model discloses a use as follows:
a method for fixing frozen pathological tissues by a real-time fixing device after the materials of the frozen pathological tissues are taken comprises the following steps:
s1, the initial state of the fixing device, namely the state that the embedding box 18 is not put into the barrel body 1: the spring 3 is in a free state, the baffle 4 is positioned at the uppermost end of the guide groove 12, the tray 6 is positioned above the fixing liquid injection hole 7 at the uppermost end at the moment, the sealing device at the position of each fixing liquid injection hole 7 is completely sealed, the cover body 5 is opened, and the fixing liquid storage cavity 8 is filled with fixing liquid, as shown in fig. 3, the fixing liquid is formalin fixing liquid with the concentration of 4%;
s2, fixing the tissue after drawing the tissue, namely, putting the tissue and the embedding box 18 into the barrel body 1 together after drawing the tissue:
s21, opening the cover body 5, enabling the embedding box 18 to be installed above the tray 6, enabling the embedding box sliding groove 182 to be correspondingly installed on the tray sliding rail 17, and covering the cover body 5 above the barrel body 1; the embedding box 18 enables the baffle plates 4 on the two sides of the tray 6 to extrude the spring 3 by pressing the tray 6, the baffle plates 4 slide downwards along the guide groove 12 by the height of the embedding box 18, and the spring top bead 10 is ejected out to enable the embedding box 18 on the tray 6 to be just clamped at the lower edge position of the fixed liquid injection hole 7; in the process of descending the tray 6, the magnetic limiting rod 13 corresponding to the position of the fixing liquid injection hole 7 slides out of the groove arranged on the magnet 14, the sealing rolling door 15 drives the magnetic limiting rod 13 to roll back to the recovery rolling shaft 16, the sealing rolling door 15 at the position of the fixing liquid injection hole 7 is opened, the fixing liquid storage cavity 8 is communicated with the embedding fixing cavity 9 through the fixing liquid injection hole 7, the fixing liquid flows into the embedding box 18, and the tissue in the embedding box 18 is fixed, as shown in fig. 4;
s22, repeating the step S21, sequentially placing the embedding boxes 18 to be fixed into the embedding fixing cavities 9, sequentially stacking the embedding boxes 18 on the tray 6 along the vertical direction, gradually opening all sealing devices in the descending process of the tray 6, continuously flowing out the fixing liquid in the fixing liquid storage cavity 8, soaking all the embedding boxes 18 in the embedding fixing cavities 9 into the fixing liquid, and fixing after the frozen pathological tissues are obtained;
s3, taking out the fixed embedding box 18: when the tray 6 moves to the lower stroke end position, the embedding cassette 18 (i.e., the one with the longest fixing time) which is fixed by the fixing liquid first is taken out through the taking-out window 11 along the tray slide rail 17. Because the order of placing the tissue blocks is the order of taking materials, the tissue blocks are taken out one by one according to the order, so that the order consistency can be ensured, and the orderly rearrangement is avoided;
s4, after the fixing device is used, extending the fixing device into the embedding fixing cavity 9 by using tools such as hooks and the like, sucking the magnetic limiting rod 13 into the groove arranged on the magnet 14 again to expand the curled sealing rolling door 15, closing the sealing device, repeating the steps S1-S3, and recycling the fixing device.
The above description is only for the specific embodiments of the present invention, but the protection scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention should be covered by the protection scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (4)
1. The utility model provides a real-time fixing device after freezing pathological tissue draws materials, it includes spring, tray (6) and is used for placing staving (1) of freezing pathological tissue embedding box, its characterized in that:
the device is characterized in that a cover body (5) is covered at an opening position at the upper end of the barrel body (1), the core of the barrel body (1) is provided with an embedding and fixing cavity (9), the embedding and fixing cavity (9) is arranged along the axis direction, a plurality of spring top beads (10) are arranged on the side wall of the embedding and fixing cavity (9), a material taking window (11) is arranged at the lower part of the side wall of the barrel body (1), the material taking window (11) is communicated with the bottom of the embedding and fixing cavity (9), and a material taking door is arranged at the material taking window (11;
two fixing liquid storage cavities (8) are symmetrically arranged in the side walls of the barrel bodies (1) on the front side and the rear side of the embedding fixing cavity (9), a plurality of fixing liquid injection holes (7) are formed in the side wall, close to one side of the embedding fixing cavity (9), of each fixing liquid storage cavity (8) at equal intervals along the vertical direction, and fixing liquid flows into the embedding fixing cavity (9) from the fixing liquid storage cavities (8) through the fixing liquid injection holes (7); a sealing device is arranged at each position of the fixed liquid injection hole (7) on the side wall of the embedding fixed cavity (9), the sealing device comprises a magnetic limiting rod (13), a magnet (14), a sealing rolling door (15) and a recovery rolling shaft (16), the magnet (14) is embedded into the upper edge of the fixed liquid injection hole (7), a groove for fixing the magnetic limiting rod (13) is formed in the outer side surface of the magnet (14), the magnetic limiting rod (13) is adsorbed on the magnet (14), one end of the sealing rolling door (15) is fixed on the magnetic limiting rod (13), the other end of the sealing rolling door (15) is fixed on the recovery rolling shaft (16), and the recovery rolling shaft (16) is arranged in the lower edge of the fixed liquid injection hole (7);
two hollow guide pillars (2) are symmetrically arranged in the side walls of the barrel bodies (1) on the left side and the right side of the embedding and fixing cavity (9), a spring (3) is arranged in each hollow guide pillar (2), and a guide groove (12) is arranged on the side wall of each hollow guide pillar (2) along the axial direction of the hollow guide pillar (2); the tray (6) is square, the tray (6) is installed in the embedding fixed cavity (9), the tray (6) and the inner wall of the embedding fixed cavity (9) are in transition fit, the positions, corresponding to the guide grooves (12), of the side walls of the two sides of the tray (6) are respectively provided with a baffle (4), the baffle (4) is arranged above the spring (3), and the baffle (4) downwards slides along the guide grooves (12) to extrude the spring (3), so that the spring (3) is in a compression state; be provided with tray slide rail (17) on the upper surface of tray (6), the axis direction of tray slide rail (17) with it is parallel to each other to get material window (11) length direction, and a plurality of embedding box (18) stack in proper order on tray (6) from top to bottom in embedding fixed chamber (9), are provided with embedding box slide rail (181) on the top surface of embedding box (18), be provided with on the bottom surface of embedding box (18) with embedding box slide rail (181) or tray slide rail (17) matched with embedding box spout (182).
2. The device for real-time fixation of sampled frozen pathological tissues of claim 1, wherein the device comprises: the lower end face of the cover body (5) is provided with a spigot matched with the embedding fixing cavity (9).
3. The device for real-time fixation of sampled frozen pathological tissues of claim 1, wherein the device comprises: the material taking windows (11) are coaxially arranged at the lower parts of the side walls of the barrel bodies (1) on the front side and the rear side of the embedding fixing cavity (9), one side of each material taking window (11) pushes an embedding box (18), the other side of each material taking window (11) pulls the embedding box (18), and the embedding boxes (18) are taken out of the barrel bodies (1) along the tray sliding rails (17).
4. The device for real-time fixation of sampled frozen pathological tissues of claim 1, wherein the device comprises: when the magnetic limiting rod (13) is adsorbed on the magnet (14), the outermost layer sealing rolling door (15) is arranged in the embedding fixing cavity (9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922431119.5U CN211528005U (en) | 2019-12-30 | 2019-12-30 | Real-time fixing device after frozen pathological tissue draws materials |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922431119.5U CN211528005U (en) | 2019-12-30 | 2019-12-30 | Real-time fixing device after frozen pathological tissue draws materials |
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| CN211528005U true CN211528005U (en) | 2020-09-18 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111077007A (en) * | 2019-12-30 | 2020-04-28 | 山西医科大学第二医院 | Real-time fixing device and method for frozen pathological tissue after material drawing |
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2019
- 2019-12-30 CN CN201922431119.5U patent/CN211528005U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111077007A (en) * | 2019-12-30 | 2020-04-28 | 山西医科大学第二医院 | Real-time fixing device and method for frozen pathological tissue after material drawing |
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