CN211511881U

CN211511881U - Tumor cell extraction and inspection device

Info

Publication number: CN211511881U
Application number: CN202020098289.6U
Authority: CN
Inventors: 刘莉华; 张晓霞; 王琴; 杨洋
Original assignee: First Peoples Hospital of Longquanyi District Chengdu
Current assignee: First Peoples Hospital of Longquanyi District Chengdu
Priority date: 2020-01-16
Filing date: 2020-01-16
Publication date: 2020-09-18
Anticipated expiration: 2030-01-16

Abstract

Tumor cells extraction censorship device, including shell and collection section of thick bamboo, the fixed collection needle that is provided with both ends all has the inclined plane needle point on the shell, it runs through the shell seal end to gather the needle, it includes the bottom plate to gather the section of thick bamboo, the barrel, the rubber stopper lid, a piston, the push rod, barrel one end sets up perpendicularly on the bottom plate, integrated into one piece in bottom plate and the barrel preparation process, bottom plate central point puts and is provided with a circular through-hole, the piston sets up in the barrel, the push rod passes the circular through-hole and the piston spiro union at bottom plate center, the push rod end is provided with the handle, the rubber. When the device is used for sampling tumor cells, the bottom plate is pressed, the collection needle penetrates through the rubber plug cover to enter the collection cylinder, then the piston is pulled, the tumor cells or tissue fluid at the focus can be sucked into the collection cylinder, then the collection cylinder is pulled out, the push rod is screwed out, the collection cylinder is a sampling and inspection integrated device, the sample can be prevented from being polluted during transfer and inspection, meanwhile, medical equipment is saved, and the detection efficiency is improved.

Description

Tumor cell extraction and inspection device

Technical Field

The utility model relates to a tumour sample technical field specifically is tumour cell extraction censorship device.

Background

The tumor is a genetic disease, is an occupied raised block formed by local tissue cell proliferation under the influence of tumorigenic factors, is not controlled by an internal regulation mechanism of a receptor, and can also spread to other parts to cause damage to a human body. After the tumor is found, the tumor needs to be sampled and detected in time, cytology detection and histology detection are generally adopted for the current detection of the tumor cells, a scalpel is generally used for cutting off a tumor block for sampling in the histology detection, the method has large wound and large harm to a patient, and a puncture needle is adopted for the cytology detection to collect the tumor cells, so that the operation is convenient, and the harm to the patient is small.

At present, cytology detection is usually adopted for detecting tumor cells, firstly, a puncture needle is adopted to collect cells at a focus, and then, the collected cells are transferred into a detection container for detection, but a sample is extremely easy to be polluted in the transferring process, and even the detection result is influenced. Therefore, there is an urgent need for a tumor cell collection device that can directly collect tumor cells for inspection without multiple metastases.

SUMMERY OF THE UTILITY MODEL

The utility model aims to overcome among the prior art need shift to the censorship container in just can censorship after tumour cell gathers, the defect of polluting the sample easily in the transfer process provides a tumour cell extraction censorship device, and when its concrete application, can realize tumour cell extraction, censorship integration, has not only reduced work load, has practiced thrift medical equipment, can effectively prevent that tumour cell's sample from receiving the pollution moreover.

The purpose of the utility model is mainly realized through the following technical scheme:

the tumor cell extracting and inspecting device comprises a shell, wherein the shell is in a hollow cylindrical shape with one open end, a collecting needle is arranged at the central position of the other end of the shell opposite to the open end, the collecting needle is in a tubular structure, the two ends of the collecting needle are provided with inclined needle points, the collecting needle penetrates through the sealed end of the shell, the collecting needle also comprises a collecting cylinder, the collecting cylinder comprises a bottom plate, a cylinder body, a rubber plug cover, a piston and a push rod, the outer diameter of the cylinder body is smaller than the inner diameter of the shell, the cylinder body is vertically arranged on the bottom plate, the bottom plate and the cylinder body are integrally formed in the manufacturing process, a circular through hole is formed in the center of the bottom plate, the piston is arranged in the cylinder body, the push rod passes through a circular through hole in the center of the bottom plate and is connected with the piston, the tail end of the push rod is provided with a handle, the rubber stopper cover is arranged at the other end of the barrel body far away from the bottom plate, and one end of the barrel body, provided with the rubber stopper cover, is positioned in the shell. When the device is used for sampling tumor cells, the bottom plate is pressed, the rubber plug cover at the opening end of the collecting cylinder is abutted to the inner wall of the collecting needle arranged on the shell, one end of the collecting needle penetrates through the rubber plug cover to enter the collecting cylinder, the other end of the collecting needle is used for deeply collecting the tumor cells in a human body, a user holds the bottom plate on one hand, the other hand pulls the push rod to drive the piston to move, cells or tissue fluid at a focus can be sucked into the collecting cylinder by utilizing pressure difference generated by the movement of the piston, the collecting cylinder is taken out, the tumor cell sample can be prevented from being polluted by the sealing effect of the rubber plug cover, meanwhile, the collecting cylinder can be used as a collecting device and can also be used as a censorship device, the sample does not need to be transferred again.

Furthermore, the length of the collecting needle in the shell is larger than the thickness of the rubber plug cover, so that the collecting needle can completely penetrate through the rubber plug cover to enter the collecting cylinder, and smooth sampling is ensured.

Furthermore, rubber stopper lid and collection section of thick bamboo tube mouth external fixation are provided with the one deck aluminum flake, closely are fixed in collection section of thick bamboo tube mouth department with rubber stopper lid, can prevent that rubber stopper lid accident from deviating from and leading to the collection sample to spill.

Further, still include the needle cap, it is provided with a cylinder I around gathering the needle to gather needle and shell surface contact department, integrated into one piece in cylinder I and the shell manufacture process, the needle cap is the cavity cylindric of one end open-ended, and the length of needle cap is greater than the length of gathering the needle and leaking outside the shell, and the needle cap covers gathers needle and its open end and cylinder I interference fit. Through the fixed action of cylinder I, can firmly be fixed in the shell with gathering the needle on, utilize the needle cap to cover and gather the needle, ensure that this device does not receive the pollution before using.

Further, the one side evagination that the piston is close to the push rod constitutes there is cylinder II, and cylinder II's diameter is greater than the diameter of circular through-hole on the bottom plate, and cylinder II other end indent constitutes has the blind hole rather than coaxial setting, and the blind hole internal diameter is the same with the diameter of push rod, is provided with the internal thread in the blind hole, and the one end that the handle was kept away from to the push rod is provided with the external screw thread with blind hole internal thread assorted. After the collection sample is completed, the push rod is rotated, so that the push rod can be taken out from the collection cylinder, the collection cylinder can be vertically placed with the base downward and the rubber plug cover upward, and the collection cylinder is used as an independent inspection device and is convenient for sample detection.

Further, the internal diameter of barrel open end is less than the barrel internal diameter, can carry on spacingly to the piston, prevents that piston and collection needle contact from appearing damaging the piston or blockking up the condition emergence of gathering the needle, further ensures that sample, censorship go on smoothly.

In conclusion, compared with the prior art, the experimental model has the following beneficial effects:

1. through the collection needle that sets up both ends and all have the inclined plane needle point and the collection section of thick bamboo that rubber stopper lid was used to one end, can be directly with the cell suction of tumour focus department to gather in the section of thick bamboo, will gather a section of thick bamboo and remove from gathering the needle, rubber stopper lid utilizes the characteristic of rubber to realize the sealed of gathering the section of thick bamboo, need not to shift sample once more and send inspection behind the sample, has avoided the contaminated condition of sample transfer in-process to take place.

2. Through dividing traditional sampler into shell and collection section of thick bamboo, collection section of thick bamboo both can regard as collection system, also can regard as the censorship container, gathers, censorship integration, has both saved medical equipment, has also practiced thrift the link of sampling censorship, has improved efficiency.

3. Connect piston and push rod through the mode of spiro union, after the sampling was accomplished, simple convenient back of screwing out the push rod makes a section of thick bamboo of gathering vertically place, the later stage of being convenient for detect.

Drawings

The accompanying drawings, which are included to provide a further understanding of the embodiments of the invention and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the invention and together with the description serve to explain the principles of the invention. In the drawings:

fig. 1 is a schematic view of the internal structure of the present invention;

FIG. 2 is a schematic view of the collection cartridge of FIG. 1;

FIG. 3 is a schematic view of the piston and cylinder of FIG. 2;

FIG. 4 is a schematic view of the structure of the push rod and the handle in FIG. 2

1-shell, 2-collection needle, 3-collection barrel, 301-bottom plate, 302-barrel, 303-rubber plug cover, 304-piston, 305-cylinder II, 306-push rod, 307-handle and 4-needle cap.

Detailed Description

To make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to the following examples and drawings, and the exemplary embodiments and descriptions thereof of the present invention are only used for explaining the present invention, and are not intended as limitations of the present invention.

Example (b):

as shown in fig. 1 to 4, the tumor cell extracting and examining device includes a housing 1, the housing 1 is a hollow cylinder with one open end, a collecting needle 2 is disposed at a central position of the other end of the housing 1 opposite to the open end, the collecting needle 2 is a tubular structure, both ends of the collecting needle are provided with a needle tip with an inclined surface, and the collecting needle 2 penetrates through the sealed end of the housing 1. Also comprises a collecting cylinder 3, the collecting cylinder 3 comprises a bottom plate 301, a cylinder body 302 and a rubber plug cover 303, the outer diameter of the cylinder 302 is smaller than the inner diameter of the shell 1, the cylinder 302 is vertically arranged on the bottom plate 301, the bottom plate 301 and the cylinder 302 are integrally formed in the manufacturing process, a circular through hole is formed in the center of the bottom plate 301, the piston 304 is arranged in the cylinder 302, a cylinder II305 is formed by protruding the back of the piston 304, the diameter of the cylinder II305 is larger than that of the circular through hole in the bottom plate 301, a blind hole which is coaxial with the cylinder II305 is formed by recessing the other end of the cylinder II305, the inner diameter of the blind hole is the same as that of the push rod 306, an internal thread is arranged in the blind hole, an external thread matched with the internal thread of the blind hole is arranged at one end of the push rod 306, the push rod 306 penetrates through the circular through hole in the center of the bottom; the rubber plug cover 303 is arranged at the other end of the cylinder 302 far away from the bottom plate 301, and the end of the cylinder 302 provided with the rubber plug cover 303 is inserted into the shell. The inner diameter of the end, provided with the rubber plug cover 303, of the cylinder body 302 is smaller than that of the cylinder body 302, so that the piston 304 can be limited, and the situation that the piston 304 is damaged or the collection needle 2 is blocked due to the fact that the piston 304 is in contact with the collection needle 2 is prevented; the length of the collection needle 2 in the housing 1 is slightly larger than the thickness of the rubber plug 303, so that the collection needle 2 can completely penetrate through the rubber plug 303 to enter the collection cylinder 3, and the sampling can be smoothly carried out.

When the device is used for sampling tumor cells, the bottom plate 301 is pressed to ensure that the rubber plug cover 303 on the collection cylinder 3 is pressed against the inner wall of the shell 1 provided with the collection needle 2, at the moment, the inclined needle head of the collection needle 2 punctures the rubber plug cover 303 to enter the collection cylinder 3, the needle head at the other end is used for collecting tumor cells in a deep human body, a user holds the bottom plate 301 and the shell 1 with one hand, pulls the push rod 306 with the other hand to drive the piston 304 to move, and the cells or tissue fluid at the focus can be sucked into the collecting cylinder 3 by utilizing the pressure difference generated by the movement of the piston 304, then the collection cylinder 3 is taken out, the tumor cell sample can be ensured not to be polluted by the sealing action of the rubber plug cover 303, the push rod 306 is rotated, the push rod 306 can be taken out of the collection cylinder 3, so that the collection cylinder 3 can be vertically and horizontally placed with the base facing downwards and the rubber plug cover 303 facing upwards to serve as an independent inspection device, and the later-stage detection of a sample is facilitated; the collecting cylinder 3 can be used as a collecting device and a delivery inspection device, the delivery inspection sample does not need to be transferred again, the sample can be effectively prevented from being polluted in the transferring process, medical equipment is saved, the delivery inspection time is saved, and the efficiency is improved.

When the utility model is specifically arranged, the rubber plug cover 303 and the outer surface of the opening of the collection cylinder 3 are fixedly provided with a layer of thin aluminum sheets, the rubber plug cover 303 is tightly fixed at the opening of the collection cylinder 3, and the collected sample can be prevented from spilling out due to accidental dropping of the rubber plug cover 303; a cylinder I is arranged at the contact part of the acquisition needle 2 and the outer surface of the shell 1 around the acquisition needle 2, and the cylinder I and the shell 1 are integrally formed in the manufacturing process, so that the acquisition needle 2 can be firmly fixed on the shell 1; a needle cap 4 is prepared by matching with the acquisition needle 2, the needle cap 4 is a hollow cylinder with an opening at one end, the length of the needle cap 4 is greater than the length of the acquisition needle 2 which leaks out of the shell 1, the needle cap 4 covers the acquisition needle 2, and the opening end of the needle cap is in interference fit with the cylinder I, so that the device is ensured not to be polluted before use; the utility model discloses the preparation process is all carried out according to the standard of medical goods, adopts ethylene oxide to disinfect, encapsulates at last after the preparation is accomplished.

The above embodiments, further detailed description of the objects, technical solutions and advantages of the present invention, it should be understood that the above embodiments are only specific embodiments of the present invention, and are not intended to limit the scope of the present invention, and any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the scope of the present invention.

Claims

1. The tumor cell extraction and inspection device comprises a shell (1), wherein the shell (1) is a hollow cylinder with one open end, and is characterized by further comprising an acquisition cylinder (3), the central position of the shell (1) opposite to the other end of the open end is provided with an acquisition needle (2), the acquisition needle (2) is of a tubular structure, the two ends of the acquisition needle are provided with inclined needle points, the acquisition needle (2) penetrates through the sealing end of the shell (1), the acquisition cylinder (3) comprises a bottom plate (301), a cylinder body (302), a rubber plug cover (303), a piston (304) and a push rod (306), the outer diameter of the cylinder body (302) is smaller than the inner diameter of the shell (1), the cylinder body (302) is vertically arranged on the bottom plate (301), the bottom plate (301) and the cylinder body (302) are integrally formed in the manufacturing process, the central position of the bottom plate (301) is provided with a circular through hole, and the piston (, the push rod (306) penetrates through a circular through hole in the center of the bottom plate (301) and is connected with the piston (304), the handle (307) is arranged at the tail end of the push rod (306), the rubber plug cover (303) is arranged at the other end, far away from the bottom plate, of the cylinder body (302), and one end, provided with the rubber plug cover (303), of the cylinder body (302) is located in the shell (1).

2. The tumor cell extraction and submission device as recited in claim 1, wherein the length of the collection needle (2) inside the housing (1) is greater than the thickness of the rubber stopper (303).

3. The tumor cell extraction and inspection device as claimed in claim 1, wherein the rubber plug (303) and the outer surface of the mouth of the collection cylinder (3) are provided with a layer of aluminum flake, so as to tightly fix the rubber plug (303) on the mouth of the collection cylinder (3).

4. The tumor cell extraction and inspection device according to claim 1, further comprising a needle cap (4), wherein a cylinder I is arranged at the contact position of the acquisition needle (2) and the outer surface of the shell (1) around the acquisition needle (2), the cylinder I and the shell (1) are integrally formed in the manufacturing process, the needle cap (4) is a hollow cylinder with an open end, the length of the needle cap (4) is greater than the length of the acquisition needle (2) which leaks out of the shell, the needle cap (4) covers the acquisition needle (2), and the open end of the needle cap is in interference fit with the cylinder I.

5. The tumor cell extracting and inspecting device according to claim 1, wherein one side of the piston (304) close to the push rod (306) protrudes outwards to form a cylinder II (305), the diameter of the cylinder II (305) is larger than that of the circular through hole on the bottom plate (301), the other end of the cylinder II (305) is recessed to form a blind hole which is coaxial with the cylinder II, the inner diameter of the blind hole is the same as that of the push rod (306), an internal thread is arranged in the blind hole, and an external thread matched with the internal thread of the blind hole is arranged at the end of one end of the push rod (306) far away from the handle (307).

6. The tumor cell extraction and submission apparatus of claim 1, wherein the inside diameter of the open end of the barrel (302) is smaller than the inside diameter of the barrel (302).