CN211455322U - Actinium-225 nuclide purifying device - Google Patents
Actinium-225 nuclide purifying device Download PDFInfo
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- CN211455322U CN211455322U CN201922308400.XU CN201922308400U CN211455322U CN 211455322 U CN211455322 U CN 211455322U CN 201922308400 U CN201922308400 U CN 201922308400U CN 211455322 U CN211455322 U CN 211455322U
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Abstract
The utility model discloses an actinium-225 purification device for nuclide relates to nuclide purification field, including first container, second container, third container and first cross valve, first container, second container and third container communicate with an interface of first cross valve respectively, further include fourth container, fifth container, sixth container and second cross valve, fourth container, fifth container and sixth container communicate with an interface of second cross valve respectively, the intercommunication has a liquid pump and a resin separation post between first cross valve and the second cross valve. The utility model discloses a set up first container, second container and third container, hold the mixed liquid that has actinium-225 nuclide simultaneously and be used for washing the liquid of actinium-225 nuclide, through setting up fourth container, fifth container, sixth container and resin separation post, hold the recycle-liquid in different stages respectively, realize actinium-225 nuclide's separation purification.
Description
Technical Field
The utility model relates to a nuclide purification field specifically is actinium-225 purification device for nuclide.
Background
A nuclide refers to an atom having a number of protons and a number of neutrons. Nuclei of the same isotope with different nuclear properties have the same proton number and different neutron number, and have different structural modes, thereby showing different nuclear properties.
Some radioactive nuclides can release alpha rays or beta rays and the like in the decay process, have stronger ionizing radiation effect, and have stronger killing effect on tumor cells or abnormal proliferation tissues and the like. Nuclide treatment means that radionuclide with therapeutic effect, such as iodine-131, strontium-89, yttrium-90, lutetium-177, radium-223 and other nuclides or labeled drugs, iodine-125 particles, phosphorus-32 application patches and the like are utilized to kill diseased cells and tissues accurately in a close range so as to achieve the purpose of treatment. The nuclide treatment comprises methods such as internal irradiation, particle or glass microsphere treatment, external application, boron neutron capture treatment and the like.
Wherein the content of the first and second substances,225the Ac (actinium-225) nuclide, as a radionuclide for therapeutic applications, is capable of emitting α radiation, and therefore, a person skilled in the art needs to consider how to efficiently extract actinium-225.
SUMMERY OF THE UTILITY MODEL
The utility model aims at providing a actinium-225 purification device for nuclide, this purification device has not only solved the purification problem of actinium-225 nuclide among the prior art, has still further improved the purification efficiency of actinium-225 nuclide.
In order to achieve the above object, the utility model provides a following technical scheme: a purification device for actinium-225 nuclide comprises a first container, a second container, a third container and a first four-way valve, wherein the first container, the second container and the third container are respectively communicated with one interface of the first four-way valve, the purification device further comprises a fourth container, a fifth container, a sixth container and a second four-way valve, the fourth container, the fifth container and the sixth container are respectively communicated with one interface of the second four-way valve, and a liquid pump and a resin separation column are communicated between the first four-way valve and the second four-way valve.
Preferably, the first four-way valve and the second four-way valve are both four-way solenoid valves.
Preferably, the liquid pump is a peristaltic pump.
Preferably, the number of the liquid pumps is one.
Preferably, one end of the liquid pump is connected with one interface of the first four-way valve, the other end of the liquid pump is communicated with an inlet of the resin separation column, and an outlet of the resin separation column is communicated with one interface of the second four-way valve.
Preferably, the fourth, fifth and sixth vessels are located below the resin separation column.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the utility model discloses a set up first container, second container and third container, hold the mixed liquid that has actinium-225 nuclide simultaneously and be used for washing the liquid of actinium-225 nuclide, through setting up fourth container, fifth container, sixth container and resin separation post, hold the recycle-liquid in different stages respectively, realize actinium-225 nuclide's separation purification.
2. And the raw material liquid and the washing liquid are quantitatively distributed in real time through the first four-way valve and the second four-way valve, enter the resin separation column and then respectively enter the corresponding collection containers, so that the full-automatic separation and purification of the actinium-225 nuclide are realized, and the purification efficiency of the actinium-225 nuclide is effectively improved.
Drawings
Fig. 1 is a schematic structural diagram of the actinium-225 nuclide purification device of the present invention.
In the figure: 1. a first container; 2. a second container; 3. a third container; 4. a first four-way valve; 5. a fourth container; 6. a fifth container; 7. a sixth container; 8. a second four-way valve; 9. a liquid pump; 10. and (4) resin separation columns.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
Example 1: referring to fig. 1, an apparatus for purifying actinide-225 species, comprising: the device comprises a first container 1, a second container 2, a third container 3 and a first four-way valve 4, wherein the first container 1, the second container 2 and the third container 3 are respectively communicated with one interface of the first four-way valve 4, the device further comprises a fourth container 5, a fifth container 6, a sixth container 7 and a second four-way valve 8, the fourth container 5, the fifth container 6 and the sixth container 7 are respectively communicated with one interface of the second four-way valve 8, and a liquid pump 9 and a resin separation column 10 are communicated between the first four-way valve 4 and the second four-way valve 8.
Example 2: referring to fig. 1, an apparatus for purifying actinide-225 species, comprising: the device comprises a first container 1, a second container 2, a third container 3 and a first four-way valve 4, wherein the first container 1, the second container 2 and the third container 3 are respectively communicated with one interface of the first four-way valve 4, the device further comprises a fourth container 5, a fifth container 6, a sixth container 7 and a second four-way valve 8, the fourth container 5, the fifth container 6 and the sixth container 7 are respectively communicated with one interface of the second four-way valve 8, and a liquid pump 9 and a resin separation column 10 are communicated between the first four-way valve 4 and the second four-way valve 8.
The first four-way valve 4 and the second four-way valve 8 are all four-way electromagnetic valves; the liquid pump 9 is a peristaltic pump; the number of the liquid pumps 9 is one; one end of the liquid pump 9 is connected with one interface of the first four-way valve 4, the other end of the liquid pump 9 is communicated with an inlet of the resin separation column 10, and an outlet of the resin separation column 10 is communicated with one interface of the second four-way valve 8; the fourth container 5, the fifth container 6 and the sixth container 7 are located below the resin separation column 10.
The working principle is as follows: when in use, the first container 1 is used for containing a mixed solution of radium-226 and actinium-225 and 4M (molar concentration) nitric acid, wherein the volume of the mixed solution is 2ml, the second container 2 is used for containing a 4M nitric acid solution, wherein the volume of the nitric acid solution is 4ml, the third container 3 is used for containing a 0.04M nitric acid solution, wherein the volume of the nitric acid solution is 3ml, after the liquid pump 9 is started, the liquid in the first container 1 enters the resin separation column 10 through the first four-way valve 4, wherein actinium-225 is captured and adsorbed on the resin separation column 10, the second four-way valve 8 is adjusted, and radium-226 nuclides flow into the fourth container 5 along with the liquid;
the first four-way valve 4 is adjusted again, the liquid in the second container 2 flows through the resin separation column 10, various impurities on the liquid are washed, the second four-way valve 8 is adjusted, and various impurities under washing flow into the fifth container 6;
and adjusting the first four-way valve 4 again, enabling the liquid in the third container 3 to flow into the resin separation column 10 through the peristaltic pump, eluting the actinium-225 nuclide on the resin separation column 10, adjusting the second four-way valve 8, and enabling the eluted actinium-225 to flow into the sixth container 7.
By adopting the technical scheme, the first container, the second container and the third container are arranged, the mixed liquid with the actinium-225 nuclide and the liquid for leaching the actinium-225 nuclide are simultaneously contained, and the fourth container, the fifth container, the sixth container and the resin separation column are arranged to respectively contain the recovery liquids at different stages, so that the separation and purification of the actinium-225 nuclide are realized;
in addition, the raw material liquid and the washing and leaching liquid are quantitatively distributed in real time through the first four-way valve and the second four-way valve, enter the resin separation column and then respectively enter the corresponding collection containers, so that the full-automatic separation and purification of the actinium-225 nuclide are realized, and the purification efficiency of the actinium-225 nuclide is effectively improved.
It is obvious to a person skilled in the art that the invention is not restricted to details of the above-described exemplary embodiments, but that it can be implemented in other specific forms without departing from the spirit or essential characteristics of the invention. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Claims (6)
1. A purification device for actinium-225 nuclide, which is characterized in that: the device comprises a first container (1), a second container (2), a third container (3) and a first four-way valve (4), wherein the first container (1), the second container (2) and the third container (3) are respectively communicated with one interface of the first four-way valve (4), the device further comprises a fourth container (5), a fifth container (6), a sixth container (7) and a second four-way valve (8), the fourth container (5), the fifth container (6) and the sixth container (7) are respectively communicated with one interface of the second four-way valve (8), and a liquid pump (9) and a resin separation column (10) are communicated between the first four-way valve (4) and the second four-way valve (8).
2. A purification apparatus for actinide-225 nuclides as in claim 1, wherein: the first four-way valve (4) and the second four-way valve (8) are both four-way electromagnetic valves.
3. A purification apparatus for actinide-225 nuclides as in claim 1, wherein: the liquid pump (9) is a peristaltic pump.
4. A purification apparatus for actinide-225 nuclides as in claim 1, wherein: the number of the liquid pumps (9) is one.
5. A purification apparatus for actinide-225 nuclides as in claim 4, wherein: one end of the liquid pump (9) is connected with one interface of the first four-way valve (4), the other end of the liquid pump (9) is communicated with an inlet of the resin separation column (10), and an outlet of the resin separation column (10) is communicated with one interface of the second four-way valve (8).
6. A purification apparatus for actinide-225 nuclides as in claim 1, wherein: the fourth container (5), the fifth container (6) and the sixth container (7) are positioned below the resin separation column (10).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922308400.XU CN211455322U (en) | 2019-12-20 | 2019-12-20 | Actinium-225 nuclide purifying device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922308400.XU CN211455322U (en) | 2019-12-20 | 2019-12-20 | Actinium-225 nuclide purifying device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211455322U true CN211455322U (en) | 2020-09-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201922308400.XU Expired - Fee Related CN211455322U (en) | 2019-12-20 | 2019-12-20 | Actinium-225 nuclide purifying device |
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| CN (1) | CN211455322U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112973445A (en) * | 2021-02-07 | 2021-06-18 | 中国科学院近代物理研究所 | Automatic processing device for separating Ac-225 and operation method thereof |
-
2019
- 2019-12-20 CN CN201922308400.XU patent/CN211455322U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112973445A (en) * | 2021-02-07 | 2021-06-18 | 中国科学院近代物理研究所 | Automatic processing device for separating Ac-225 and operation method thereof |
| CN112973445B (en) * | 2021-02-07 | 2023-09-12 | 中国科学院近代物理研究所 | Automatic processing device for separating Ac-225 and operation method thereof |
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200908 Termination date: 20211220 |
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| CF01 | Termination of patent right due to non-payment of annual fee |