CN211443498U

CN211443498U - Kit for preparing autologous NK cells

Info

Publication number: CN211443498U
Application number: CN201922463153.0U
Authority: CN
Inventors: 沈健; 沈卓凡
Original assignee: Jiangsu Mengbili Biological Technology Co ltd
Current assignee: Jiangsu Mengbili Biological Technology Co ltd
Priority date: 2019-12-31
Filing date: 2019-12-31
Publication date: 2020-09-08
Anticipated expiration: 2029-12-31

Abstract

The utility model discloses a kit for preparing autologous NK cell, the test kit comprises a kit, it has the inner cup through screw thread swing joint to be close to top department outside the kit, the kit overcoat is equipped with outer box, heat preservation under outer box inner chamber fixedly connected with, outer box top swing joint has the enclosing cover, heat preservation on the enclosing cover inner chamber fixedly connected with, enclosing cover inner chamber top is close to center department swing joint and has the slide bar, the slide bar overcoat is equipped with the slide pipe, slide pipe bottom fixedly connected with clamp plate, clamp plate bottom fixedly connected with buffer layer, outer box is close to top department swing joint outward and has the annular lid, and annular lid inner circle and enclosing cover are close to bottom department swing joint outward, the utility model discloses a series of structure makes this device have characteristics such as barrier propterty is good and thermal insulation performance is good.

Description

Kit for preparing autologous NK cells

Technical Field

The utility model relates to a preparation autologous NK cell's kit technical field specifically is a kit for preparing autologous NK cell.

Background

Autologous NK cells, namely natural killer cells, are derived from bone marrow lymphoid stem cells, the differentiation and development of the autologous NK cells depend on bone marrow and thymus microenvironment, the autologous NK cells are mainly distributed in bone marrow, peripheral blood, liver, spleen, lung and lymph nodes, are important immune cells of an organism, are not only related to tumor resistance, virus infection resistance and immune regulation, but also participate in hypersensitivity and autoimmune disease under certain conditions, a special kit is needed in the preparation process of the autologous NK cells, the existing kit has no good protection setting, and has poor heat preservation performance, influences the preparation and storage of the autologous NK cells, and the defects of poor protection performance, poor heat preservation performance and the like exist, so the kit for preparing the autologous NK cells is provided.

SUMMERY OF THE UTILITY MODEL

The utility model provides a technical problem lie in overcoming prior art's protective properties and defect such as heat preservation performance is poor, provide a kit for preparing autologous NK cell. The kit for preparing the autologous NK cells has the characteristics of good protective performance, good heat preservation performance and the like.

In order to achieve the above object, the utility model provides a following technical scheme: the utility model provides a kit for preparing autologous NK cell, includes the box body, be close to top department outside the box body and have the inner cup through screw thread swing joint, the box body overcoat is equipped with outer box, heat preservation under the outer box inner chamber fixedly connected with, outer box top swing joint has the enclosing cover, heat preservation on the enclosing cover inner chamber fixedly connected with, the enclosing cover inner chamber top is close to center department swing joint and has the slide bar, the slide bar overcoat is equipped with the slide bar, slide bar bottom fixedly connected with clamp plate, clamp plate bottom fixedly connected with buffer layer, be close to top department swing joint outward and have the annular lid outside the outer box, and annular lid inner circle and enclosing cover are close to bottom department swing joint outward.

Preferably, a reagent port is formed in the position, close to the top, of the side wall of the right side of the box body, a sealing ring is installed in the reagent port, and a sealing plug is plugged in the sealing ring.

Preferably, the top of the outer box is fixedly connected with an inner thread ring, the outer part of the inner thread ring is movably connected with the inner ring of the outer cover close to the bottom through threads, and the inner ring of the inner thread ring is attached to the outer ring of the lower heat-insulating layer close to the top.

Preferably, a lower thread ring is sleeved outside the outer box and close to the top, and the lower thread ring is movably connected with the inner ring of the annular cover and close to the bottom through threads.

Preferably, an upper thread ring is sleeved at a position, close to the bottom, outside the outer cover, and the upper thread ring is movably connected with the position, close to the top, of the inner ring of the annular cover through threads.

Preferably, the bearing is installed at the position, close to the center, of the top of the outer cover, the through hole matched with the sliding rod is formed in the top of the inner cavity of the upper heat-insulating layer, and the top end of the sliding rod sequentially penetrates through the through hole and the inner ring of the bearing to be movably connected with the top of the inner cavity of the outer cover.

Preferably, the clamp plate top is close to left and right sides department fixedly connected with pipe respectively, and the pipe endotheca is equipped with the round bar, the round bar overcoat is equipped with the spring, both ends respectively with last heat preservation inner chamber top and pipe top fixed connection about the spring.

Compared with the prior art, the beneficial effects of the utility model are that:

1. in the technical scheme, the outer cover can be rotated and screwed down on the outer ring of the inner thread ring through the threads by the mutual matching of the outer box, the outer cover, the lower heat-insulating layer and the upper heat-insulating layer, so that the box body is sealed in the inner cavity of the outer box, the lower heat-insulating layer and the upper heat-insulating layer can protect and insulate the inner cavity of the outer box, the box body is protected and insulated, and the characteristic of good temperature performance can be effectively realized;

2. in the technical scheme, the round rod, the round pipe and the spring are matched with each other, so that the pressing plate can press downwards when the outer cover is rotated and screwed, the round rod slides in the round pipe, the spring is compressed and contracted, the box body in the inner cavity of the outer box is protected, and the characteristic of good protection performance can be effectively realized;

3. in this technical scheme, through last thread circle, mutually support between lower thread circle and the annular lid, can realize covering the outer lane of establishing last thread circle with the annular lid from the top down cover in the outer lane of enclosing lid to realize rotatory annular lid, and then realize that the annular lid passes through the outer screw thread downstream of last thread circle and lower thread circle, play and screw up the annular lid and block the effect in gap between enclosing lid and the outer box, can effectively realize the characteristics that its warm nature can be good.

Drawings

Fig. 1 is a schematic structural view of the present invention;

FIG. 2 is a top view of FIG. 1;

fig. 3 is an enlarged view of fig. 1 at a.

Reference numbers in the figures: 1. a box body; 2. an inner cover; 3. an outer box; 4. an outer cover; 5. a lower insulating layer; 6. an upper heat-insulating layer; 7. a slide bar; 8. a slide pipe; 9. pressing a plate; 10. a buffer layer; 11. a round bar; 12. a circular tube; 13. a spring; 14. a sealing plug; 15. screwing a thread ring; 16. a lower thread ring; 17. an annular cover; 18. an internal thread ring.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1-3, the present invention provides a technical solution: a kit for preparing autologous NK cells comprises a box body 1, a reagent port is formed in the position, close to the top, of the side wall of the right side of the box body 1, a sealing ring is installed in the reagent port, a sealing plug 14 is filled in the sealing ring, an inner cover 2 is movably connected to the position, close to the top, of the outer side of the box body 1 through threads, an outer box 3 is sleeved outside the box body 1, a lower heat-insulating layer 5 is fixedly connected to the inner cavity of the outer box 3, an outer cover 4 is movably connected to the top of the outer box 3, an inner thread ring 18 is movably connected to the position, close to the bottom, of the inner ring of the outer cover 4 through threads, the inner ring of the inner thread ring 18 is attached to the position, close to the top, of the outer ring of the lower heat-insulating layer 5, an upper heat-insulating layer 6 is fixedly connected to the inner, the top of the inner cavity of the upper heat-insulating layer 6 is provided with a through hole matched with the slide rod 7, the top end of the slide rod 7 sequentially penetrates through the through hole and the inner ring of the bearing to be movably connected with the top of the inner cavity of the outer cover 4, and the outer cover 3, the outer cover 4, the lower heat-insulating layer 5 and the upper heat-insulating layer 6 are matched with each other, so that the outer ring of the inner thread ring 18 of the outer cover 4 can be rotated and screwed through threads, the box body 1 is sealed in the inner cavity of the outer cover 3, the inner cavity of the outer box 3 is protected and insulated by the lower heat-insulating layer 5 and the upper heat-insulating layer 6, the protection and heat-insulating effects;

the bottom of the sliding tube 8 is fixedly connected with a pressing plate 9, the bottom of the pressing plate 9 is fixedly connected with a buffer layer 10, the top of the pressing plate 9, which is close to the left side and the right side, is respectively and fixedly connected with a round tube 12, a round rod 11 is sleeved in the round tube 12, a spring 13 is sleeved outside the round rod 11, the upper end and the lower end of the spring 13 are respectively and fixedly connected with the top of an inner cavity of the upper heat-insulating layer 6 and the top of the round tube 12, through the mutual matching of the round rod 11, the round tube 12 and the spring 13, the pressing plate 9 can be pressed downwards when the outer cover 4 is rotated and screwed down, so that the round rod 11 slides in the round tube 12, and the spring 13 is pressed and contracted, the box body 1 in the inner cavity of the outer box 3 is protected, the characteristic of good protection performance can be effectively realized, the annular cover 17 is movably connected at the position, which is close to the top, and the lower thread ring 16 is movably connected with the inner ring of the annular cover 17 close to the bottom through threads, the outer part of the outer cover 4 close to the bottom is sleeved with the upper thread ring 15, the outer part of the upper thread ring 15 is movably connected with the inner ring of the annular cover 17 close to the top through threads, the annular cover 17 can be sleeved on the outer ring of the outer cover 4 of the annular cover 17 from top to bottom through the mutual matching of the upper thread ring 15, the lower thread ring 16 and the annular cover 17, so that the annular cover 17 is rotated, the annular cover 17 moves downwards through the threads outside the upper thread ring 15 and the lower thread ring 16, the annular cover 17 is screwed and blocks a gap between the outer cover 4 and the outer box 3, and the characteristic of good temperature performance can be effectively realized.

The working principle is as follows: when the utility model is used, the inner cover 2 is covered on the top of the box body 1 to rotate and screw up, the covered box body 1 is placed in the inner cavity of the outer box 3, then the outer cover 4 is rotated and screwed up at the outer ring of the inner thread ring 18 through the thread, thereby realizing that the box body 1 is sealed in the inner cavity of the outer box 3, further realizing that the inner cavity of the outer box 3 is protected and insulated by the lower insulating layer 5 and the upper insulating layer 6, playing the role of protecting and insulating the box body 1, effectively realizing the characteristic of good temperature performance, the pressing plate 9 presses downwards when the outer cover 4 is rotated and screwed up, thereby realizing that the round rod 11 slides in the round pipe 12, further realizing the compression and contraction of the spring 13, playing the role of protecting the box body 1 in the inner cavity of the outer box 3, effectively realizing the characteristic of good protection performance, meanwhile, the slide rod 7 slides in the slide pipe 8, playing the role of movable connection, the role of buffering of the buffer layer 10 in the downward movement process of the pressing, inner cup 2 and box body 1 have been protected, establish the outer lane of last fillet of thread 15 with annular lid 17 from the top down cover in the outer lane of enclosing cover 4 after that, thereby realize rotatory fillet of thread 17, and then realize that annular lid 17 passes through fillet of thread 15 and the outer screw thread downstream of 16 of fillet of thread down, play and screw up annular lid 17 and block the effect in gap between enclosing cover 4 and the outer box 3, can effectively realize the characteristics that its warm performance is good, in addition, if need mend liquid or dropping liquid to 1 inner chamber of box body, can not open inner cup 2, directly extract sealing plug 14 and operate through the reagent mouth, portability and practicality have been improved.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. A kit for the preparation of autologous NK cells, comprising a cartridge body (1), characterized in that: box body (1) is close to top department outward and has inner cup (2) through screw thread swing joint, box body (1) overcoat is equipped with outer box (3), heat preservation (5) under outer box (3) inner chamber fixedly connected with, outer box (3) top swing joint has enclosing cover (4), heat preservation (6) are gone up to enclosing cover (4) inner chamber fixedly connected with, enclosing cover (4) inner chamber top is close to center department swing joint has slide bar (7), slide bar (7) overcoat is equipped with slide bar (8), slide bar (8) bottom fixedly connected with clamp plate (9), clamp plate (9) bottom fixedly connected with buffer layer (10), outer box (3) are close to top department swing joint outward and have annular lid (17), and annular lid (17) inner circle and enclosing cover (4) are close to bottom department swing joint outward.

2. A kit for the preparation of autologous NK cells according to claim 1, characterized in that: a reagent port is formed in the position, close to the top, of the side wall of the right side of the box body (1), a sealing ring is installed in the reagent port, and a sealing plug (14) is plugged in the sealing ring.

3. A kit for the preparation of autologous NK cells according to claim 1, characterized in that: the top of the outer box (3) is fixedly connected with an inner thread ring (18), the inner thread ring (18) is movably connected with the inner ring of the outer cover (4) close to the bottom through threads, and the inner ring of the inner thread ring (18) is attached to the outer ring of the lower heat-insulating layer (5) close to the top.

4. A kit for the preparation of autologous NK cells according to claim 1, characterized in that: a lower thread ring (16) is sleeved at the position, close to the top, outside the outer box (3), and the lower thread ring (16) is movably connected with the position, close to the bottom, of the inner ring of the annular cover (17) through threads.

5. A kit for the preparation of autologous NK cells according to claim 1, characterized in that: an upper thread ring (15) is sleeved at the position, close to the bottom, outside the outer cover (4), and the upper thread ring (15) is movably connected with the position, close to the top, of the inner ring of the annular cover (17) through threads.

6. A kit for the preparation of autologous NK cells according to claim 1, characterized in that: the bearing is installed near the center of the top of the outer cover (4), the through hole matched with the sliding rod (7) is formed in the top of the inner cavity of the upper heat-insulating layer (6), and the top end of the sliding rod (7) penetrates through the through hole and the inner ring of the bearing in sequence to be movably connected with the top of the inner cavity of the outer cover (4).

7. A kit for the preparation of autologous NK cells according to claim 1, characterized in that: the heat-insulation plate is characterized in that the top of the pressing plate (9) is close to the left side and the right side and is respectively fixedly connected with a round pipe (12), a round rod (11) is sleeved in the round pipe (12), a spring (13) is sleeved outside the round rod (11), and the upper end and the lower end of the spring (13) are respectively fixedly connected with the top of an inner cavity of the upper heat-insulation layer (6) and the top of the round pipe (12).