CN211236431U - Microscopic imaging system for epidemiological analysis - Google Patents
Microscopic imaging system for epidemiological analysis Download PDFInfo
- Publication number
- CN211236431U CN211236431U CN201922077101.XU CN201922077101U CN211236431U CN 211236431 U CN211236431 U CN 211236431U CN 201922077101 U CN201922077101 U CN 201922077101U CN 211236431 U CN211236431 U CN 211236431U
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- imaging system
- light source
- microscopic imaging
- glass slide
- microscope body
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Abstract
The utility model discloses a micro-imaging system for epidemiology analysis, include: the microscope comprises a microscope body, a glass slide and a cover glass which are matched with the microscope body, and a light source device; wherein the cover glass is arranged on one surface of the glass slide close to the objective lens in the microscope body, a sample liquid is arranged between the glass slide and the cover glass, and the light source device can irradiate the sample liquid on the glass slide through the emitted ultraviolet rays so as to inactivate bacteria in the sample liquid; the upper surface of the cover glass is also covered with an ultraviolet-proof film for blocking ultraviolet rays irradiated on the glass slide from entering an objective lens of the microscope body; the utility model discloses can utilize the ultraviolet ray to make its deactivation in the microscopic observation process.
Description
Technical Field
The utility model relates to an epidemiology analysis experimental apparatus field, concretely relates to a micro-imaging system for epidemiology analysis.
Background
Epidemics refer to infectious diseases that can infect a large population. Can be used for treating infectious diseases such as influenza, meningitis, cholera, etc. In epidemiological analysis, viruses, bacteria and pathogenic microorganisms are often observed with a microscope.
Ultraviolet rays refer to solar rays with a wavelength of 200nm to 380nm, and include 3 types: the wavelength of UV-A is 315 nm-380 nm, the wavelength of UV-B is 280 nm-315 nm, and the wavelength of UV-C is 200 nm-280 nm. The solar rays (290-2000 nm) reaching the earth's surface contain about 13% UV, 97% UV-A, 3% UV-B and approximately 0% UV-C. The only damage to human skin is UV-A, UV-B. The UV-C ultraviolet lamp is prepared by a special process and is used for disinfection and sterilization.
Wherein the ultraviolet ray with uv-C wave is the best ultraviolet ray with about 254 nm. The ultraviolet ray can kill various microorganisms including bacteria propagules, spores, mycobacteria, viruses, fungi, rickettsia, mycoplasma and the like, and has broad spectrum.
The sterilization principle is that the ultraviolet rays irradiate microorganisms such as bacteria, viruses and the like to destroy the structure of DNA (deoxyribonucleic acid) in a body, so that the microorganisms die or lose the reproductive capacity immediately. Quartz uv lamps have the advantage of identifying authenticity. The ultraviolet sterilization capability of different wave bands is different, and the bacteria can be killed only by short-wave ultraviolet (200-300nm), wherein the sterilization capability is strongest in the range of 250-270nm, and the process of killing the bacteria cannot be observed by a microscope.
If the bacteria can be killed by using ultraviolet rays in the microscopic observation process and the inactivation process of the bacteria can be observed, the research means of epidemiology can be expanded, and a theoretical basis is provided for further controlling and preventing the spread of epidemic diseases.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is to utilize the ultraviolet ray to make its deactivation in the microscopic observation process to a micro-imaging system for epidemiology analysis is provided.
In order to solve the technical problem, the utility model provides a following technical scheme:
a microscopic imaging system for epidemiological analysis, comprising: the microscope comprises a microscope body, a glass slide and a cover glass which are matched with the microscope body, and a light source device; wherein the cover glass is arranged on one surface of the glass slide close to the objective lens in the microscope body, a sample liquid is arranged between the glass slide and the cover glass, and the light source device can irradiate the sample liquid on the glass slide through the emitted ultraviolet rays so as to inactivate bacteria in the sample liquid; the upper surface of the cover glass is also covered with an ultraviolet-proof film for blocking ultraviolet rays irradiated on the glass slide from entering the objective lens of the microscope body.
Preferably, the light source device is arranged in the light through hole or the light source box.
Preferably, the light source device comprises a plurality of UV-LED lamp beads and a fixing block, wherein the UV-LED lamp beads are fixedly mounted on the fixing block.
Preferably, the light source box is fixedly arranged on the object stage and arranged on the side surface of the glass slide, and a plurality of through holes are formed in the light source box and used for guiding light rays of the light source device and irradiating the light rays on the glass slide.
Preferably, the light through hole is obliquely arranged on the object stage and is communicated with a central hole, and the central hole is arranged on the object stage and is positioned right below the glass slide.
Preferably, the inclination angle of the light through hole ranges from 15 ° to 45 °.
Preferably, the shape of the upper surface of the object stage is: circular or rectangular or square or diamond.
Preferably, the objective table is arranged right below the objective lens of the microscope body, and the objective table is further provided with a signal input interface for connecting with a connection port on the microscope body.
Preferably, the microscope body is disposed in an enclosed environment that is shielded from ultraviolet radiation.
Preferably, the microscope body is connected with a control and display terminal.
The utility model discloses the beneficial effect who reaches is:
the utility model discloses utilize the light source device to shine and cover on the slide glass and the upper surface of cover glass and prevent the ultraviolet ray membrane, make the utility model discloses can utilize the ultraviolet ray to kill the bacterium at microscopic observation's in-process, observe its inactivation process, provide the theoretical foundation for further control and the propagation of prevention epidemic disease.
Drawings
The accompanying drawings are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention, and together with the description serve to explain the invention and not to limit the invention.
In the drawings:
fig. 1 is a schematic structural diagram of a microscopic imaging system provided by the present invention;
FIG. 2 is a schematic structural diagram of the case and the control and display terminal shown in FIG. 1;
fig. 3 is a schematic partial structural view of a microscopic imaging system provided by the present invention;
FIG. 4 is a cross-sectional view of the microscopic imaging system shown in FIG. 3;
fig. 5 is a schematic structural view of a light source box of the microscopic imaging system provided by the present invention;
fig. 6 is a partial cross-sectional view of another embodiment of a microscopic imaging system provided by the present invention.
The microscope comprises a drawing object stage 1, a microscope body 2, a glass slide 3, a light source box 4, a light source device 5, a cover glass 6, a box body 7, a control and display terminal 8, an ultraviolet-proof film 9 and sample liquid 10.
Detailed Description
The preferred embodiments of the present invention will be described in conjunction with the accompanying drawings, and it will be understood that they are presented herein only to illustrate and explain the present invention, and not to limit the present invention.
As shown in fig. 1 to 2, a microscopic imaging system for epidemiological analysis comprises an object stage 1 and a microscope body 2, wherein the object stage 1 is disposed under an objective lens of the microscope body 2, and the object stage 1 is further provided with a signal input interface for connecting with a connection port on the microscope body 2. The microscope body 2 is connected to a control and display terminal 8. The upper surface of the object table 1 is square in shape, in other embodiments the upper surface of the object table 1 may be round or rectangular or diamond shaped. The microscope body 2 is a general manual or automatic microscope, and may be used for image acquisition or human eye observation. The microscope is an automatic microscope for pattern acquisition, and the driving signal loading of the light source device 5 can be integrated into a microscope control terminal, such as a PC. In the present embodiment, as shown in fig. 2, the microscope body 2 is disposed in the box 7 to isolate ultraviolet rays to protect a user. In other embodiments, the box body 7 is disposed on the stage 1 and movably connected to the stage 1, the box body 7 seals the slide, the cover glass and the light source box 4 in the inner cavity thereof, and the box body 7 is provided with a window for observing the objective lens of the microscope body 2. Wherein, the active link can be a screw, a buckle, a magnet, etc. Screws, buckles and magnets are all conventional accessories in the field, so the utility model discloses no longer explain in detail box 7 and objective table 1 and be connected.
As shown in fig. 3 to 4, the microscopic imaging system further includes a glass slide 3 and a cover glass 6, wherein the cover glass 6 is disposed above the glass slide 3, a sample liquid 10 is disposed between the glass slide 3 and the cover glass 6, wherein the sample liquid 10 of the glass slide 6 is a bacteria culture liquid, and the upper surface of the cover glass 6 is covered with an ultraviolet-proof film 9, and in other embodiments, the ultraviolet-proof film 9 may be disposed on an objective lens of the microscope body 2 to prevent ultraviolet radiation to an observer. The microscopic imaging system also comprises a light source device 5, the light source device irradiates the glass slide 3 through the emitted ultraviolet rays, so that the inactivation treatment is carried out on bacteria or other microorganisms in the sample liquid, and meanwhile, the ultraviolet rays can be prevented from entering an objective lens during observation through the arranged ultraviolet ray preventing film 9, and ultraviolet ray radiation is caused to an observer. The light source device 5 comprises four UV-LED lamp beads and a fixed block, wherein the UV-LED lamp beads are fixedly arranged on the fixed block, the UV-LED lamp beads emit ultraviolet rays and irradiate on the glass slide, so that the ultraviolet rays emitted by the UV-LED lamp beads inactivate the bacterial culture solution on the glass slide, a chip for controlling the ultraviolet intensity is arranged on the UV-LED lamp beads, and a wireless control module on the chip is connected with the control and display terminal 8 through wireless, so that an experimenter can adjust the intensity of the ultraviolet rays emitted by the UV-LED lamp beads through the control and display terminal 8, and can better observe the bacterial process in the bacterial culture solution killed by the ultraviolet rays; the UV-LED lamp bead and the fixing block may be connected by a detachable component or may be connected by gluing with glue, wherein the detachable component may be, for example, a screw nut fitting piece, the fixing block and the light through hole on the light source box or the object stage 1 may be connected by a detachable component or may be connected by gluing with glue, and the detachable component may be, for example, a screw nut fitting piece.
In one embodiment, the light source device 5 is disposed in a light source box 4 as shown in fig. 3 to 5, the light source box 4 is fixedly mounted on the stage 1 and is disposed at the side of the glass slide 3, and the light source box 4 is provided with a plurality of through holes for light rays of the light source device 5 to pass through and irradiate on the glass slide 3.
In another embodiment, as shown in fig. 6, the light source device 5 is disposed in a light passing hole which is obliquely disposed on the stage 1 and communicates with a central hole which is disposed on the stage 1 and is located right under the slide glass 3 and which allows light from the lower portion of the microscope body 2 to pass therethrough and irradiate on the slide glass 3. In the present embodiment, the inclination angles of the light passing holes are 15 °, 20 °, 30 °, and 45 °. Through the microscopic imaging system that above embodiment provided, the ultraviolet ray that can utilize the light source device transmission shines in order to realize the bacterium deactivation to sample liquid at the observation in-process, can also utilize the setting to shelter from the ultraviolet ray of incidence at the ultraviolet ray membrane of preventing on cover glass surface simultaneously to avoid getting into the eyepiece of microscope body, thereby, both realized carrying out the ultraviolet ray deactivation to the bacterium at the experiment observation in-process, carried out safety protection to the experimenter again.
It is noted that terms such as light source device and light ray through hole are used herein only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between such entities or operations. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications may be made to the embodiments described in the foregoing embodiments, or equivalents may be substituted for elements thereof. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (10)
1. A microscopic imaging system for epidemiological analysis, comprising: the microscope comprises a microscope body, a glass slide and a cover glass which are matched with the microscope body, and a light source device; wherein:
the cover glass is arranged on one surface, close to the objective lens in the microscope body, of the glass slide, sample liquid is arranged between the glass slide and the cover glass, and the light source device can irradiate the sample liquid on the glass slide through emitted ultraviolet rays so as to inactivate bacteria in the sample liquid; the upper surface of the cover glass is also covered with an ultraviolet-proof film for blocking ultraviolet rays irradiated on the glass slide from entering the objective lens of the microscope body.
2. A microscopic imaging system for epidemiological analysis according to claim 1, characterized in that: the light source device is arranged in a light through hole of the objective table or a light source box.
3. A microscopic imaging system for epidemiological analysis according to claim 1, characterized in that: the light source device comprises a plurality of UV-LED lamp beads and a fixed block, wherein the UV-LED lamp beads are fixedly arranged on the fixed block.
4. A microscopic imaging system for epidemiological analysis according to claim 2, characterized in that: the light source box is fixedly arranged on the object stage and arranged on the side surface of the glass slide, and a plurality of through holes are formed in the light source box and used for guiding light rays of the light source device and irradiating the light rays on the glass slide.
5. A microscopic imaging system for epidemiological analysis according to claim 2, characterized in that: the light through hole is obliquely arranged on the objective table and is communicated with a central hole, and the central hole is arranged on the objective table and is positioned right below the glass slide.
6. A microscopic imaging system for epidemiological analysis according to claim 5, characterized in that: the inclination angle range of the light ray through holes is 15-45 degrees.
7. A microscopic imaging system for epidemiological analysis according to claim 4, characterized in that: the shape of the upper surface of the object stage is as follows: circular or rectangular or square or diamond.
8. A microscopic imaging system for epidemiological analysis according to claim 4, characterized in that: the objective table is arranged under an objective lens of the microscope body, and a signal input interface is further arranged on the objective table and used for being connected with a connecting port on the microscope body.
9. A microscopic imaging system for epidemiological analysis according to claim 8, characterized in that: the microscope body is arranged in a closed environment capable of isolating ultraviolet radiation.
10. A microscopic imaging system for epidemiological analysis according to claim 8, characterized in that: the microscope body is connected with the control and display terminal.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922077101.XU CN211236431U (en) | 2019-11-27 | 2019-11-27 | Microscopic imaging system for epidemiological analysis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201922077101.XU CN211236431U (en) | 2019-11-27 | 2019-11-27 | Microscopic imaging system for epidemiological analysis |
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| Publication Number | Publication Date |
|---|---|
| CN211236431U true CN211236431U (en) | 2020-08-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201922077101.XU Expired - Fee Related CN211236431U (en) | 2019-11-27 | 2019-11-27 | Microscopic imaging system for epidemiological analysis |
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| CN (1) | CN211236431U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114279782A (en) * | 2021-12-07 | 2022-04-05 | 深圳先进技术研究院 | Microscopic sample preparation device and use method thereof |
-
2019
- 2019-11-27 CN CN201922077101.XU patent/CN211236431U/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114279782A (en) * | 2021-12-07 | 2022-04-05 | 深圳先进技术研究院 | Microscopic sample preparation device and use method thereof |
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| GR01 | Patent grant | ||
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| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200811 |
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| CF01 | Termination of patent right due to non-payment of annual fee |