CN211227147U - Placenta stem cell collection system - Google Patents
Placenta stem cell collection system Download PDFInfo
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- CN211227147U CN211227147U CN201921888474.9U CN201921888474U CN211227147U CN 211227147 U CN211227147 U CN 211227147U CN 201921888474 U CN201921888474 U CN 201921888474U CN 211227147 U CN211227147 U CN 211227147U
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- motor
- plate
- fixedly connected
- stem cell
- shaft
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- 210000000130 stem cell Anatomy 0.000 title claims abstract description 23
- 210000002826 placenta Anatomy 0.000 title claims abstract description 15
- 238000003756 stirring Methods 0.000 claims description 53
- 210000004991 placental stem cell Anatomy 0.000 claims description 6
- 230000000694 effects Effects 0.000 abstract description 18
- 238000000034 method Methods 0.000 abstract description 11
- 230000008569 process Effects 0.000 abstract description 9
- 238000005119 centrifugation Methods 0.000 abstract 1
- 239000011435 rock Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 230000009471 action Effects 0.000 description 6
- 230000021164 cell adhesion Effects 0.000 description 3
- 238000007790 scraping Methods 0.000 description 3
- 230000008878 coupling Effects 0.000 description 2
- 238000010168 coupling process Methods 0.000 description 2
- 238000005859 coupling reaction Methods 0.000 description 2
- 210000003954 umbilical cord Anatomy 0.000 description 2
- 230000004075 alteration Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 210000004700 fetal blood Anatomy 0.000 description 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000005059 placental tissue Anatomy 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Images
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- Mixers Of The Rotary Stirring Type (AREA)
- Accessories For Mixers (AREA)
Abstract
The utility model discloses a placenta stem cell collecting device, which belongs to the technical field of bioengineering, and comprises a bottom plate, wherein a motor a is embedded and installed on the upper surface of the bottom plate, a main gear is fixedly connected on an output shaft of the motor a, a bearing a is clamped on the upper surface of the bottom plate and is rotatably connected to the bottom end of a rotating shaft, a driven gear is fixedly arranged on the outer side wall of the rotating shaft, and the driven gear is meshed with the main gear; place the container on carrying the thing board, utilize the hand wheel to rotate and drive the screw rod and rotate, it is close to each other to push two splint under the effect of swivel nut, thereby press from both sides the container tightly, avoid taking place to rock at centrifugal process easily, utilize motor a's drive to make simultaneously and carry the thing board rotation, thereby carry out centrifugal operation, centrifugation is effectual, the container that is applicable to different models uses, it is effectual to the collection of stem cells, simultaneously under the effect of pneumatic cylinder, can be with parts such as (mixing) shaft suspension, the follow-up of being convenient for is cleared up etc..
Description
Technical Field
The utility model belongs to the technical field of bioengineering, concretely relates to placenta stem cell collection system.
Background
The placenta stem cells scientifically discovered at present comprise: the method comprises the following steps of obtaining stem cells by collecting placenta tissues, wherein the placenta stem cells are obtained by three channels generally when a newborn descends, the first step is to collect the hematopoietic stem cells from an umbilical cord blood source, the second step is to collect umbilical cord-derived mesenchymal stem cells from an umbilical cord, and the third step is to collect the placenta stem cells from the placenta source.
At present, traditional collection system function is more single, is difficult to carry out centrifugal operation to the stem cell in the different containers, and is relatively poor to the collection effect of stem cell, and parts such as (mixing) shaft are in inside the equipment simultaneously, are difficult to carry out follow-up clearance etc. and wash the degree of difficulty big.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a placenta stem cell collection system to solve the problem that proposes among the above-mentioned background art.
In order to achieve the above object, the utility model provides a following technical scheme: a placenta stem cell collection system, comprising a base plate, the upper surface of the base plate is embedded with a motor a, and fixedly connected with a master gear on the output shaft of the motor a, the upper surface of the base plate is clamped with a bearing a, and the bearing a is rotatably connected with the bottom of a rotating shaft, the outer side wall of the rotating shaft is fixedly provided with a slave gear, and the slave gear is meshed with the master gear, the top end of the rotating shaft is fixedly connected with the lower surface of a carrying plate, the outer side wall of the carrying plate is clamped with two screw sleeves, and the two screw sleeves are internally and uniformly in threaded connection with a screw rod, the screw rod is positioned at one end of the outer side wall of the carrying plate and is fixedly connected with a hand wheel, one end of the screw rod positioned at the inner side of the carrying plate is rotatably connected in the bearing b, the bearing b is clamped in a side face of a, the four corners of the upper surface of the bottom plate are respectively fixedly connected with the lower surface of the top plate through four stand columns, the lower surface of the top plate is fixedly provided with two hydraulic cylinders, the telescopic ends of the two hydraulic cylinders are fixedly connected with the upper surface of the lifting plate, the upper surface of the lifting plate is fixedly provided with a motor b, the output shaft of the motor b is fixedly connected with the top end of a stirring shaft through a shaft coupling, the outer side wall of the stirring shaft is fixedly provided with a stirring blade a and a crushing blade, the outer side wall of the top end of the stirring shaft is fixedly connected with one end of the two sleeve columns opposite to each other, the sleeve columns are movably connected with adjusting rods, one ends of the adjusting rods, which are positioned at the inner sides of the sleeve columns, are elastically connected with the inner side walls of the sleeve columns through springs, the other ends of the adjusting rods are fixedly, the motor a, the hydraulic cylinder and the motor b are respectively electrically connected with an external power supply.
By adopting the scheme, the container is placed on the object carrying plate by arranging the motor a, the main gear, the driven gear, the hand wheel, the screw rod, the threaded sleeve, the bearing b, the connecting block and the clamping plates, the screw rod is driven to rotate by the rotation of the hand wheel, the two clamping plates are driven to be close to each other under the action of the threaded sleeve, so that the container is clamped, the phenomenon that the container is easy to shake in the centrifugal process is avoided, meanwhile, the object carrying plate is rotated by the driving of the motor a, so that the centrifugal operation is carried out, the centrifugal effect is good, the device is suitable for containers of different models, the collection effect on stem cells is good, the stirring shaft is driven to rotate by the motor b by arranging the hydraulic cylinder, the motor b, the shaft coupler, the stirring shaft, the stirring blade a and the crushing blade, so that the stirring blade a rotates to stir, the, be convenient for follow-up clear up etc. through setting up the cover post, adjusting pole, spring, fixed block, dead lever, stirring leaf b and scraper blade, utilize the elastic force effect of spring to make the scraper blade can hug closely the inside wall of container, avoid stem cell adhesion in centrifugal process at the inside wall of container, on the other hand utilizes stirring leaf b to stir the operation around the container is inboard, improves stirring effect.
What needs to be explained in the above scheme is:
the model of the motor a and the model of the motor b can be YX3-100L 1-4; the type of the hydraulic cylinder can be STA-63-100-15-1T.
As a preferred embodiment, two sides of the bottom surface of the clamping plate are respectively and fixedly connected with two limiting slide blocks, and the two limiting slide blocks are respectively and slidably connected in two limiting slide grooves formed in the upper surface of the carrying plate.
Adopt above-mentioned scheme, utilize spacing slider to slide in spacing spout to improve the centre gripping effect of splint, guarantee the stability of splint after the stability of splint centre gripping when removing and splint.
In a preferred embodiment, two rubber pads are fixedly bonded to the inner side wall of the clamping plate.
Adopt above-mentioned scheme, utilize setting up of rubber pad to avoid splint to cause the clamp to hinder to the lateral wall of container, improve the frictional force between splint and the container simultaneously, improve the centre gripping effect.
As a preferred embodiment, sliding sleeves are respectively clamped at four corners of the lifting plate, and the four sliding sleeves are respectively sleeved on the four upright posts.
By adopting the scheme, the sliding sleeve is utilized to slide on the upright post, so that the lifting plate is more stable when moving up and down.
In a preferred embodiment, the sleeve column is screwed with a fixing bolt.
By adopting the scheme, the adjusting rod can be fixed through the fixing bolt, and the adjusting rod is prevented from being always in an extension state under the action of the spring.
In a preferred embodiment, the stirring blade b is located on a side close to the stirring shaft, and the scraper blade is located on a side far from the stirring shaft.
Adopt above-mentioned scheme, utilize the elasticity effect of spring to make the scraper blade can hug closely the inside wall of container, avoid stem cell adhesion in centrifugal process at the inside wall of container, on the other hand utilizes stirring leaf b to stir the operation around the container is inboard, improves stirring effect.
Compared with the prior art, the beneficial effects of the utility model are that:
the placenta stem cell collecting device is characterized in that a container is placed on a carrying plate through the arrangement of the motor a, the main gear, the driven gear, the hand wheel, the screw rod, the threaded sleeve, the bearing b, the connecting block and the clamping plates, the screw rod is driven to rotate by the rotation of the hand wheel, the two clamping plates are driven to be close to each other under the action of the threaded sleeve, so that the container is clamped, the phenomenon that the container is easy to shake in the centrifugal process is avoided, meanwhile, the carrying plate is rotated by the driving of the motor a, the centrifugal operation is carried out, the centrifugal effect is good, the placenta stem cell collecting device is suitable for containers of different;
according to the placental stem cell collection device, the hydraulic cylinder, the motor b, the coupler, the stirring shaft, the stirring blade a and the crushing blade are arranged, the motor b is used for driving the stirring shaft to rotate, so that the stirring blade a rotates to perform stirring operation, the centrifugal effect is improved, and meanwhile, under the action of the hydraulic cylinder, components such as the stirring shaft and the like can be suspended, so that subsequent cleaning and the like are facilitated;
this placenta stem cell collection system utilizes the elasticity effect of spring through setting up the cover post, adjusting pole, spring, fixed block, dead lever, stirring leaf b and scraper blade to make the scraper blade can hug closely the inside wall of container, avoid the stem cell adhesion in centrifugal process at the inside wall of container, on the other hand utilizes stirring leaf b to stir the operation all around of container inboard, improves stirring effect.
Drawings
Fig. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic structural view of the top view of the carrier plate of the present invention;
fig. 3 is a schematic view of the connection structure of the section of the middle sleeve column of the present invention.
In the figure: 1. a base plate; 2. an electric motor a; 3. a main gear; 4. a bearing a; 5. a rotating shaft; 6. A slave gear; 7. a loading plate; 8. a threaded sleeve; 9. a screw; 10. a hand wheel; 11. a bearing b; 12. Connecting blocks; 13. a splint; 14. a limiting slide block; 15. a rubber pad; 16. a column; 17. a top plate; 18. a hydraulic cylinder; 19. a lifting plate; 20. a sliding sleeve; 21. a motor b; 22. a coupling; 23. a stirring shaft; 24. a stirring blade a; 25. crushing the blade; 26. sleeving a column; 27. adjusting a rod; 28. a spring; 29. fixing the bolt; 30. a fixed block; 31. fixing the rod; 32. a stirring blade b; 33. a scraper.
Detailed Description
The present invention will be further described with reference to the following examples.
The following examples are intended to illustrate the invention, but are not intended to limit the scope of the invention. The condition in the embodiment can be further adjusted according to concrete condition the utility model discloses a it is right under the design prerequisite the utility model discloses a simple improvement of method all belongs to the utility model discloses the scope of claiming.
Referring to fig. 1-3, the present invention provides a placenta stem cell collecting device, comprising a bottom plate 1, wherein a motor a2 is embedded on the upper surface of the bottom plate 1, a main gear 3 is fixedly connected to the output shaft of the motor a2, a bearing a4 is connected to the upper surface of the bottom plate 1, the bearing a4 is rotatably connected to the bottom end of a rotating shaft 5, a driven gear 6 is fixedly arranged on the outer side wall of the rotating shaft 5, the driven gear 6 is meshed with the main gear 3, the top end of the rotating shaft 5 is fixedly connected to the lower surface of a carrying plate 7, two screw sleeves 8 are connected to the outer side wall of the carrying plate 7, a screw 9 is threadedly connected to each of the two screw sleeves 8, a hand wheel 10 is fixedly connected to one end of the outer side wall of the carrying plate 7 of the screw 9, one end of the screw 9 located inside the carrying plate 7 is rotatably connected to the bearing b11, a bearing b11 is connected to one side surface of a connecting block, the connecting block 12 is fixedly connected to the bottom surface of the clamping plate 13, two sides of the bottom surface of the clamping plate 13 are respectively fixedly connected with the two limiting sliding blocks 14, and the two limiting sliding blocks 14 are respectively connected in the two limiting sliding grooves formed in the upper surface of the carrying plate 7 in a sliding manner (see fig. 2); utilize spacing slider 14 to slide in spacing spout to improve the centre gripping effect of splint 13, guarantee the stability of splint 13 when removing and the steadiness behind the splint 13 centre gripping.
Two rubber pads 15 (see fig. 2) are fixedly adhered to the inner side wall of the clamping plate 13; utilize the setting of rubber pad 15 to avoid splint 13 to cause the clamp to hinder to the lateral wall of container, improve the frictional force between splint 13 and the container simultaneously, improve the centre gripping effect.
The four corners of the upper surface of the bottom plate 1 are respectively fixedly connected with the lower surface of the top plate 17 through four upright posts 16, the lower surface of the top plate 17 is fixedly provided with two hydraulic cylinders 18, the telescopic ends of the two hydraulic cylinders 18 are fixedly connected with the upper surface of the lifting plate 19, the four corners of the lifting plate 19 are respectively clamped with sliding sleeves 20, and the four sliding sleeves 20 are respectively sleeved on the four upright posts 16 (see fig. 1); the sliding sleeve 20 is used to slide on the upright 16, so that the lifting plate 19 is more stable when moving up and down.
The upper surface of the lifting plate 19 is fixedly provided with a motor b21, an output shaft of the motor b21 is fixedly connected with the top end of the stirring shaft 23 through a coupler 22, the outer side wall of the stirring shaft 23 is fixedly provided with stirring blades a24 and crushing blades 25, the outer side wall of the top end of the stirring shaft 23 is fixedly connected with one end of the two sleeve columns 26 opposite to each other, the sleeve columns 26 are movably connected with adjusting rods 27, and the sleeve columns 26 are in threaded connection with fixing bolts 29 (see fig. 1 and 3); the adjusting lever 27 can be fixed by the fixing bolt 29, and the adjusting lever 27 is prevented from being always extended under the action of the spring 28.
One end of the adjusting rod 27, which is positioned at the inner side of the sleeve column 26, is elastically connected with the inner side wall of the sleeve column 26 through a spring 28, the other end of the adjusting rod 27 is fixedly connected with a fixed block 30, the lower surface of the fixed block 30 is fixedly provided with a fixed rod 31, the outer side wall of the fixed rod 31 is respectively provided with a stirring blade b32 and a scraping plate 33, the stirring blade b32 is positioned at one side close to the stirring shaft 23, and the scraping plate 33 is positioned at one side far away from the stirring shaft 23 (; by utilizing the elastic force of the spring 28, the scraper 33 can be tightly attached to the inner side wall of the container, stem cells are prevented from being adhered to the inner side wall of the container in the centrifugal process, and on the other hand, the stirring blade b32 is utilized to stir the periphery of the inner side of the container, so that the stirring effect is improved.
The motor a2, the hydraulic cylinder 18 and the motor b21 are respectively electrically connected with an external power supply.
When the centrifugal dry cell separation device is used, a container is placed on the object carrying plate 7, the hand wheel 10 is rotated to drive the screw rod 9 to rotate, the two clamping plates 13 are pushed to be close to each other under the action of the screw sleeve 8, so that the container is clamped, shaking in the centrifugal process is avoided easily, meanwhile, the motor a2 is used for driving, the object carrying plate 7 is rotated through the meshing of a driving wheel and the driven gear 6, so that centrifugal operation is carried out, in the centrifugal process, the hydraulic cylinder 18 is started to push the lifting plate 19 to descend, so that the stirring shaft 23 can be located in the container, the fixing bolt 29 is unscrewed to enable the adjusting rod 27 to extend outwards under the pushing of the spring 28, after the scraping plate 33 is attached to the inner side wall of the container, the fixing bolt 29 is screwed and the motor b21 is started, the stirring shaft 23 is rotated through the motor b 21.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. The utility model provides a placenta stem cell collection system, includes bottom plate (1), its characterized in that: the upper surface of bottom plate (1) inlays to establish and installs motor a (2), and fixedly connected with master gear (3) on the output shaft of motor a (2), the upper surface joint of bottom plate (1) has bearing a (4), and bearing a (4) rotate to be connected in the bottom of pivot (5), the lateral wall of pivot (5) is fixed to be equipped with from gear (6), and from gear (6) and master gear (3) meshing mutually, the top of pivot (5) and the lower fixed surface who carries thing board (7) are connected, the lateral wall joint that carries thing board (7) has two swivel nuts (8), and equal threaded connection has screw rod (9) in two swivel nuts (8), screw rod (9) are located one of carrying thing board (7) lateral wall and serve fixedly connected with hand wheel (10), screw rod (9) are located the inboard one end of carrying thing board (7) and rotate and connect in bearing b (11), the bearing b (11) is connected to one side face of the connecting block (12), the connecting block (12) is slidably connected to a groove formed in the object carrying plate (7), the connecting block (12) is fixedly connected to the bottom face of the clamping plate (13), four corners of the upper surface of the bottom plate (1) are respectively fixedly connected with the lower surface of the top plate (17) through four upright posts (16), two hydraulic cylinders (18) are fixedly mounted on the lower surface of the top plate (17), the telescopic ends of the two hydraulic cylinders (18) are fixedly connected with the upper surface of the lifting plate (19), a motor b (21) is fixedly mounted on the upper surface of the lifting plate (19), an output shaft of the motor b (21) is fixedly connected with the top end of the stirring shaft (23) through a shaft coupler (22), and a stirring blade a (24) and a crushing blade (25) are fixedly arranged on the outer side wall of the stirring shaft (23), the utility model discloses a stirring shaft (23) top, including (mixing) shaft (23), the one end fixed connection that the lateral wall is relative with two cover columns (26) on (mixing) shaft (23) top, swing joint has regulation pole (27) in cover column (26), adjust pole (27) and be located the inboard one end of cover column (26) and pass through spring (28) and the inside wall elastic connection of cover column (26), fixedly connected with fixed block (30) on the other end of regulation pole (27), and the lower fixed surface of fixed block (30) is equipped with dead lever (31), be equipped with stirring leaf b (32) and scraper blade (33) on the lateral wall of dead lever (31) respectively, motor a (2), pneumatic cylinder (18) and motor b (21) respectively with external power supply electric connection.
2. The placental stem cell collection device according to claim 1, wherein: the two sides of the bottom surface of the clamping plate (13) are respectively fixedly connected with the two limiting sliding blocks (14), and the two limiting sliding blocks (14) are respectively connected in the two limiting sliding grooves formed in the upper surface of the carrying plate (7) in a sliding mode.
3. The placental stem cell collection device according to claim 1, wherein: the inner side wall of the clamping plate (13) is fixedly provided with two rubber pads (15) in a bonding manner.
4. The placental stem cell collection device according to claim 1, wherein: four corners of the lifting plate (19) are respectively connected with a sliding sleeve (20), and the four sliding sleeves (20) are respectively sleeved on the four upright posts (16).
5. The placental stem cell collection device according to claim 1, wherein: the sleeve column (26) is connected with a fixing bolt (29) in a threaded manner.
6. The placental stem cell collection device according to claim 1, wherein: the stirring blade b (32) is positioned on one side close to the stirring shaft (23), and the scraper blade (33) is positioned on one side far away from the stirring shaft (23).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921888474.9U CN211227147U (en) | 2019-11-05 | 2019-11-05 | Placenta stem cell collection system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921888474.9U CN211227147U (en) | 2019-11-05 | 2019-11-05 | Placenta stem cell collection system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN211227147U true CN211227147U (en) | 2020-08-11 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921888474.9U Active CN211227147U (en) | 2019-11-05 | 2019-11-05 | Placenta stem cell collection system |
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| Country | Link |
|---|---|
| CN (1) | CN211227147U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113122425A (en) * | 2021-03-08 | 2021-07-16 | 孔祥玲 | Stem cell centrifugal equipment capable of being fixed quickly and fixing method |
-
2019
- 2019-11-05 CN CN201921888474.9U patent/CN211227147U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113122425A (en) * | 2021-03-08 | 2021-07-16 | 孔祥玲 | Stem cell centrifugal equipment capable of being fixed quickly and fixing method |
| CN113122425B (en) * | 2021-03-08 | 2022-07-26 | 上海揽微赛尔生物科技有限公司 | Stem cell centrifugal equipment capable of being fixed quickly and fixing method |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240517 Address after: 441000 Building 6, Xiangyang Science and Technology Park, Intersection of Wuxi Road and Zhuhai Avenue, High tech Development Zone, Xiangyang City, Hubei Province (Residence Application) Patentee after: Huazhong Stem Cell (Hubei) Biotechnology Co.,Ltd. Country or region after: China Address before: 441000 building 6, Xiangyang science and Technology City Park, intersection of Wuxi road and Zhuhai Avenue, high tech Zone, Xiangyang City, Hubei Province Patentee before: HUBEI WISTEM BIOTECH Co.,Ltd. Country or region before: China |
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| TR01 | Transfer of patent right |