CN211188788U - Deep brain electrical stimulation system with multiple channels and multiple stimulation sources - Google Patents

Deep brain electrical stimulation system with multiple channels and multiple stimulation sources Download PDF

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CN211188788U
CN211188788U CN201921118611.0U CN201921118611U CN211188788U CN 211188788 U CN211188788 U CN 211188788U CN 201921118611 U CN201921118611 U CN 201921118611U CN 211188788 U CN211188788 U CN 211188788U
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circuit
stimulation
implanted
wireless charging
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李晓波
李�浩
屠亚威
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Hangzhou Chengnuo Medical Technology Co ltd
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Hangzhou Chengnuo Medical Technology Co ltd
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Abstract

The utility model discloses a deep electro photoluminescence system of brain of many stimulus sources of multichannel, including implanted neural stimulator, programme-controlled appearance, stimulation electrode, special operation portion, wherein implanted neural stimulator is including implanting logic control unit, power management unit, wireless charging unit, implantation wireless communication unit, special ASIC unit, function protection unit, programme-controlled appearance includes programme-controlled logic control unit, display element, status light indicating unit, the mutual unit of button, voice prompt unit, the wireless transmitting unit that charges, memory cell, programme-controlled wireless communication unit, USB communication unit, battery charging management unit. The system has the effectiveness of a traditional deep brain stimulation system (DBS), greatly reduces side effects and brings better use experience for patients.

Description

Deep brain electrical stimulation system with multiple channels and multiple stimulation sources
Technical Field
The utility model belongs to the neural amazing field relates to a deep electro photoluminescence system of brain of many stimulus sources of multichannel.
Background
Parkinson's Disease is a common nervous system degenerative Disease of middle-aged and elderly people, and is characterized by pathological changes mainly caused by progressive degeneration of nigral dopaminergic neurons and formation of lewy bodies, biochemical changes caused by reduction of dopamine transmitter in striatal regions and imbalance of dopamine and acetylcholine transmitter, and clinical manifestations of non-motor symptoms such as tremor, myotonia, bradykinesia, dyskinesia of postural balance disorder, hyposmia, constipation, abnormal sleeping behavior, depression and the like.
In recent years, there has been significant progress in both the understanding of the pathogenesis of parkinson and the discovery of early diagnostic biomarkers, as well as in the search for methods and means of treatment thereof. Each Parkinson patient can show motor symptoms and non-motor symptoms sequentially or simultaneously, but the two symptoms are accompanied in the whole disease process, and sometimes, a plurality of non-motor symptoms are generated, so that not only the motor symptoms influence the working and living capacities of the patients, but also the non-motor symptoms obviously interfere the life quality of the patients. Therefore, we adopted comprehensive and combined treatment of the motor symptoms and non-motor symptoms of Parkinson.
Methods and means of treatment include: medication, surgical treatment, exercise therapy, psychological counseling, care and the like. The drug therapy is the first choice and is the main treatment means in the whole treatment process, and the surgical therapy is an effective supplement of the drug therapy. The early drug treatment has obvious effect, and the long-term treatment has obvious decline of the curative effect, or serious motor fluctuation and dyskinesia appear. In 1987, Benabid, a functional neurosurgeon in France, accidentally applied high frequency stimulation to the brain of a patient, and as a result, found that the limbs of the patient were not trembled and had no significant side effects, thereby resulting in DBS therapy. Surgical therapies mainly include nuclear destruction and Deep Brain Stimulation (DBS), which is the primary choice for its relative non-invasiveness, safety and controllability.
Deep Brain Stimulation (DBS) achieves the goal of alleviating and/or controlling symptoms by implanting electrodes in the brain to deliver electrical impulses to the involved nerve nuclei that control movement, regulating abnormal neuroelectrical activity. The operation targets comprise GPi on the inner side of the globus pallidus, VIM (thalamus ventral intermediate nucleus) and STN (thalamus subthalamic nucleus), wherein DBS (cardiac myotonia activator) has the most obvious curative effect on improving tremor, rigidity, bradykinesia and dyskinesia in the STN. In addition, DBS has been approved by the FDA for the treatment of psychiatric disorders, such as obsessive compulsive disorder (anorexia, net addiction, drug dependence, etc.), and attempts to treat psychological disorders such as depression, tourette syndrome, etc.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a deep electro photoluminescence system of brain of many independent stimulus sources of multichannel, this design is at the inside multichannel independent voltage source that directly sets up of implanted neural stimulator, like the independent voltage source of 2 and more than 2 passageways, multichannel independent current source, like the independent current source of 8 and more than 8 passageways, multichannel independent current trap, like the independent current trap of 8 and more than 8 passageways, every voltage source, current source, the digital interface of the special ASIC unit of current trap accessible carries out programming configuration.
Different stimulation amplitudes, stimulation pulse widths and stimulation frequencies can be set for each voltage source, current source and current trap, so that output electric pulse signals can simultaneously act on corresponding contact ends of the brain implant electrodes through the blocking capacitors and the electrode configuration network, different charge effect ranges can be generated by configuring the stimulation signal amplitudes, the pulse widths, the frequencies and the electrode combinations of different electrode channels, the stimulation side effects on peripheral nuclei are greatly reduced while the traditional DBS stimulation curative effect is achieved, and the experience and satisfaction of patients are further improved. In order to reduce the damage of the electrical pulse stimulation to brain tissues, the charge density at the electrode end point can be controlled while multiple current sources work simultaneously to generate a targeting stimulation effect, and the charge density is less than 30uC/cm under the conventional stimulation occasion2/Phase。
In order to achieve the above purpose, the technical scheme of the utility model is that: a multi-channel multi-stimulus source deep brain electrical stimulation system comprises an implanted nerve stimulator, a program controller, a stimulation electrode and a special operation part, wherein the implanted nerve stimulator is respectively connected with the program controller and the stimulation electrode, and the program controller is also connected with the special operation part;
the implantable neural stimulator comprises an implanted logic control unit, a power management unit, a wireless charging unit, an implanted wireless communication unit, a special ASIC unit and a function protection unit;
the program control instrument comprises a program control logic control unit, a display unit, a status light indicating unit, a key interaction unit, a voice prompt unit, a wireless charging transmitting unit, a storage unit, a program control wireless communication unit, a USB communication unit and a battery charging management unit, wherein,
the implanted logic control unit is respectively connected with the power management unit, the wireless charging unit, the implanted wireless communication unit, the special ASIC unit and the function protection unit and controls the circuits;
the power management unit comprises a battery, a power management circuit and a measurement protection circuit, wherein the power management circuit is used for performing voltage stabilization and management on a signal output by the wireless charging unit through rectification, the output of the battery is subjected to voltage boosting or voltage reduction conversion to a required voltage amplitude, and the measurement protection circuit is used for measuring and monitoring the internal resistance of the battery, the voltage of the battery and the output of the battery;
the wireless charging unit receives a wireless charging signal from the outside of the body and rectifies the bidirectional resonance signal to obtain pulsating direct current, and the wireless charging frequency is KHz level or MHz level;
the implanted wireless communication unit is near field coupling communication or far field communication, and bidirectional data transmission between the implanted nerve stimulator and the in-vitro program controller is realized; the wireless communication unit can also adopt radio frequency communication or magnetic element induction;
the special ASIC unit comprises a highly integrated stimulation generating circuit, an electrode configuration circuit and a feedback circuit, wherein the stimulation generating circuit can generate a plurality of voltage sources, a plurality of current sources and a plurality of current wells, the voltage sources, the current sources and the current wells are independent from one another, and the feedback circuit measures the impedance of an electrode implantation part and collects brain waveforms of a designated area;
the function protection unit prevents stimulation signals from overcurrent, overvoltage and frequency upper limit protection and maximum pulse width protection, and prevents excessive charge stimulation to protect the safety of an implanted part; monitoring the total loop current, and pre-judging the short circuit, half short circuit and open circuit conditions of the connection end points;
the program control logic control unit controls the display unit, the state lamp indicating unit, the key interaction unit, the voice prompt unit, the wireless charging transmitting unit, the storage unit, the program control wireless communication unit, the USB communication unit and the battery charging management unit;
the display unit comprises a liquid crystal or a nixie tube, displays an operation menu interface and guides to use the program controller;
the status light indicating unit comprises L ED with a plurality of colors and prompts the charging status;
the key interaction unit comprises a plurality of keys, and the keys are pressed to select the program control function;
the voice prompt unit comprises a buzzer or a voice player and is used for sending out prompt sounds in different states to prompt the operating state;
the wireless charging transmitting unit wirelessly charges a battery in the implanted nerve stimulator and wirelessly charges a short-distance induction type wireless charging technology or magnetic/electric field resonance wireless charging, and the wireless charging frequency is KHz level or MHz level;
the storage unit is an external Flash chip and stores and displays characters and graphic pictures;
the program-controlled wireless communication unit comprises an antenna, a low-power-consumption Bluetooth communication module and/or a near-field coupling communication module and/or a far-field communication module, the near-field coupling communication module comprises pulse frequency modulation or pulse width modulation or digital amplitude modulation or frequency shift keying modulation, and bidirectional data transmission between the implantable neural stimulator and the program-controlled instrument is realized through the antenna; the low-power consumption Bluetooth communication module carries out bidirectional data transmission and control between the program control instrument and the special operation part;
the USB communication unit comprises a USB2.0 or USB3.0 interface, and realizes program control and data transmission of the program control instrument by special control software at a computer end;
the battery charging management unit comprises a charging management circuit and a rechargeable battery, wherein the charging management circuit is used for carrying out charging management on the rechargeable battery and changing the output voltage Buck/Boost of the rechargeable battery to a required voltage amplitude;
the stimulation electrodes are cylindrical, fan-shaped and strip-shaped, and the number of the electrodes is 4-12.
Preferably, the implanted logic control unit comprises an MCU or an MPU or a DSP or an FPGA or an ASIC.
Preferably, the rectification in the wireless charging unit is full-bridge rectification or full-wave rectification.
Preferably, the near field coupling communication of the implanted wireless communication unit is pulse frequency modulation or pulse width modulation or digital amplitude modulation or frequency shift keying modulation.
Preferably, the stimulation generating circuit of the special ASIC unit includes a logic controller digital interface, a digital decoding circuit, and a logic control circuit, which are respectively connected to the voltage source circuit, the current sink circuit, and the feedback circuit; the stimulation generating circuit can generate a plurality of voltage sources, a plurality of current sources and a plurality of current traps, all the voltage sources, the current sources and the current traps are mutually independent, and amplitude, frequency and pulse width control is carried out according to a digital interface of the logic controller.
The utility model provides an implanted neurostimulator has set up feedback circuit, possesses the biofeedback function, can be used to survey the brain tissue impedance at electrode implantation position and measure the brain wave form (EEG) in specific nucleus district, the analytic processing of EEG wave form can be configured into implanted neurostimulator internal logic unit according to system sensitivity needs and carry out waveform analysis processing or send EEG signal to external control software through wireless communication mode and carry out EEG analytic processing, through can extracting the relevant eigenvalue of brain wave like β ripples etc. to EEG signal analytic processing, this eigenvalue can be used to closed loop control nerve stimulation activation or standby, consequently, the utility model discloses configuration that can be nimble is continuous type stimulation mode or based on brain wave form characteristic prejudgement's stimulation mode, especially to characteristic prejudgement mode, starts the electro photoluminescence when the parkinsonism brain wave form eigenvalue reaches trigger condition, and the electro photoluminescence is closed when being less than trigger condition, prevents excessive useless stimulation, and more power saving.
The beneficial effects at least comprise:
1. the output stimulation is provided with a plurality of stimulation sources, can be selected according to the treatment needs of actual clinical patients, and each path is independent and separate, does not interfere with each other and can be freely configured;
2. the multichannel independent voltage source, current source and current trap loop can flexibly configure amplitude, pulse width and frequency in a program control manner so as to realize a targeted stimulation effect, ensure a curative effect and reduce side effects;
3. the highly integrated analog-digital hybrid ASIC design has the functions and simultaneously further reduces the power consumption of the circuit, saves the volume of the circuit and enhances the security of the system;
4. the stimulation electrode is provided with 4 or more electrode contacts on the left brain and the right brain respectively, the electrode contacts can be in a cylindrical shape, a sector shape, a strip shape or other special shapes, each contact can be flexibly configured into a positive electrode or a negative electrode, and the implantable nerve stimulator shell can be used as the positive electrode;
5. the brain wave pre-judging system has a closed-loop biofeedback function, can acquire impedance and brain wave patterns of corresponding parts, provides a continuous stimulation mode and a pre-judging stimulation mode based on brain wave characteristic values, can reduce excessive useless stimulation in the pre-judging stimulation mode and saves system power consumption;
6. the wireless charging of the implanted nerve stimulator is self-adaptive, so that the eddy effect in the charging process can be further reduced, and the temperature rise is reduced;
7. the implantable nerve stimulator is chargeable and has longer service life;
8. the power management unit in the implanted nerve stimulator can effectively monitor the internal resistance of the battery, the capacity of the battery, the terminal voltage of the battery and the total current of a loop, and can estimate the battery endurance and the corrosion condition of a system connecting terminal in advance.
Drawings
Fig. 1 is a block diagram of a deep brain electrical stimulation system with multiple channels and multiple stimulation sources according to an embodiment of the present invention;
fig. 2 is a block diagram of an implantable neurostimulator of a multichannel multi-stimulation-source deep brain electrical stimulation system according to an embodiment of the present invention;
fig. 3 is a structural block diagram of a program controller of a multichannel multi-stimulus-source deep brain electrical stimulation system according to an embodiment of the present invention;
fig. 4 is a block diagram of the structure of the ASIC unit dedicated to the deep brain electrical stimulation system with multiple channels and multiple stimulation sources according to the embodiment of the present invention;
fig. 5 is a schematic wireless charging diagram of a multi-channel multi-stimulus source deep brain electrical stimulation system according to an embodiment of the present invention;
fig. 6 is a schematic diagram of the application of the stimulation electrode of the multi-channel multi-stimulation-source deep brain electrical stimulation system according to the embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
On the contrary, the invention is intended to cover alternatives, modifications, equivalents and alternatives which may be included within the spirit and scope of the invention as defined by the appended claims. Furthermore, in order to provide a better understanding of the present invention to the public, certain specific details are set forth in the following detailed description of the invention. It will be apparent to those skilled in the art that the present invention may be practiced without these specific details.
Referring to fig. 1-5, a structural block diagram of a deep brain electrical stimulation system with multiple channels and multiple stimulation sources according to an embodiment of the present invention is shown, including an implantable neurostimulator 10, a program controller 20, a stimulation electrode 30, and a dedicated operation unit 40, wherein the implantable neurostimulator 10 is connected to the program controller 20 and the stimulation electrode 30, and the program controller 20 is further connected to the dedicated operation unit 40;
the implantable neurostimulator 10 comprises an implanted logic control unit 101, a power management unit 102, a wireless charging unit 103, an implanted wireless communication unit 104, a special-purpose ASIC unit 105 and a function protection unit 106;
the program-controlled instrument 20 comprises a program-controlled logic control unit 201, a display unit 202, a status light indicating unit 203, a key interaction unit 204, a voice prompt unit 205, a wireless charging transmitting unit 206, a storage unit 207, a program-controlled wireless communication unit 208, a USB communication unit 209 and a battery charging management unit 210, wherein,
the implanted logic control unit 101 is connected to the power management unit 102, the wireless charging unit 103, the implanted wireless communication unit 104, the dedicated ASIC unit 105, and the function protection unit 106, respectively, and controls the above circuits;
the power management unit 102 comprises a battery, a power management circuit and a measurement protection circuit, wherein the power management circuit performs voltage stabilization and management on a signal rectified and output by the wireless charging unit 103, performs voltage boosting or voltage reduction conversion on the output of the battery to a required voltage amplitude, and the measurement protection circuit performs measurement and monitoring on the internal resistance of the battery, the voltage of the battery and the output of the battery; the power management circuit comprises a power management chip which is small in package, high in boosting efficiency, low in ripple noise and high in reliability and is used for boosting the voltage of the 2.2V-4.2V battery to 9V-15V or other voltage levels and providing stable voltage for the implanted nerve stimulator 10;
the wireless charging unit 103 is a short-distance induction type wireless charging technology or a (magnetic/electric) field resonance wireless charging technology, receives a wireless charging signal from the outside of a body and rectifies a bidirectional resonance signal to obtain pulsating direct current, the wireless charging frequency is KHz level or MHz level, the receiving coil 601 can be placed inside or outside an implanted nerve stimulator shell, the shell can be a titanium alloy shell or a titanium alloy and ceramic combined shell, and the wireless charging has the functions of charging state detection, overcurrent protection, overvoltage protection and metal foreign matter detection;
the implanted wireless communication unit 104 is near field coupling communication or far field communication, and realizes bidirectional data transmission between the implanted neurostimulator 10 and the external program controller 20; the wireless communication unit can also adopt radio frequency communication or magnetic element induction;
the ASIC unit 105 includes a highly integrated stimulation generating circuit, an electrode configuration circuit 507, and a feedback circuit 508, the stimulation generating circuit may generate multiple voltage sources, multiple current sources, and multiple current wells, each voltage source, each current source, and each current well are independent of each other, the feedback circuit 508 measures the electrode implantation site, i.e., the impedance of the load 509, and collects brain waveforms in a designated area;
the function protection unit 106 prevents the stimulation signals from overcurrent, overvoltage, frequency upper limit protection and maximum pulse width protection, and prevents excessive charge stimulation to protect the safety of the implanted part; monitoring the total loop current, and pre-judging the short circuit, half short circuit and open circuit conditions of the connection end points;
the program control logic control unit 201 controls the display unit 202, the status light indicating unit 203, the key interaction unit 204, the voice prompt unit 205, the wireless charging transmitting unit 206, the storage unit 207, the program control wireless communication unit 208, the USB communication unit 209 and the battery charging management unit 210;
the display unit 202 comprises a liquid crystal or a nixie tube, displays an operation menu interface and guides the use of the program controller 20;
the status light indicating unit 203 includes L ED of several colors, which indicates the charging status;
the key interaction unit 204 comprises a plurality of keys, and the keys are pressed to select the program control function;
the voice prompt unit 205 comprises a buzzer or a voice player, and sends out prompt sounds of different states to prompt the operation state;
the wireless charging and transmitting unit 206 wirelessly charges a battery in the implantable neurostimulator 10, and wirelessly charges a short-distance induction type wireless charging technology or magnetic/electric field resonance wireless charging, wherein the wireless charging frequency is KHz level or MHz level, and the wireless charging and transmitting unit 206 has the functions of transmitting coil 610 alignment prompt, antenna alignment guide, metal foreign object detection and current protection and temperature control in the charging process;
the storage unit 207 is an external Flash chip and stores display characters and graphic pictures;
the program-controlled wireless communication unit 208 comprises an antenna, a low-power-consumption bluetooth communication module and/or a near-field coupling communication module and/or a far-field communication module, the near-field coupling communication module comprises pulse frequency modulation or pulse width modulation or digital amplitude modulation or frequency shift keying modulation, and bidirectional data transmission between the implantable neurostimulator 10 and the program-controlled instrument 20 is realized through the antenna; the low-power consumption Bluetooth communication module carries out bidirectional data transmission and control between the program controller 20 and the special operating part 40;
the USB communication unit 209 includes a USB2.0 or USB3.0 interface, and implements program control and data transmission of the program controller 20 by the computer-side dedicated control software;
the battery charging management unit 210 includes a charging management circuit and a rechargeable battery, and the charging management circuit performs charging management on the rechargeable battery and changes the output voltage Buck/Boost of the rechargeable battery to a required voltage amplitude;
the stimulating electrodes 30 are cylindrical, fan-shaped and strip-shaped, and the number of the electrodes is 4-12.
In a specific embodiment, the implanted logic control unit 101 includes an MCU or an MPU or a DSP or an FPGA or an ASIC.
The near field coupled communication of the implanted wireless communication unit 104 is pulse frequency modulation or pulse width modulation or digital amplitude modulation or frequency shift keying modulation.
Structure of the dedicated ASIC unit 105 referring to fig. 4, the stimulus generating circuit includes a logic controller digital interface 501, a digital decoding circuit 502, a logic control circuit 503, which are connected to a voltage source circuit 504, a current source circuit 505, a current sink circuit 506, and a feedback circuit 508, respectively; the stimulus generating circuit can generate multiple voltage sources, multiple current sources and multiple current sinks, each of which is independent of the other and performs amplitude, frequency and pulse width control according to the logic controller digital interface 501. The special ASIC unit 105 is ingenious in internal design, and can realize the output of stimulation signals with a larger dynamic range by only adjusting the boosting value of external power supply voltage on the premise of not changing the circuit structure, for example, when the voltage range of 10V is within the range of 0-20mA current, 0-10V voltage, 0-250Hz frequency and 0-620uS pulse width, the power supply voltage is boosted to 15V or higher voltage value, and the output range of the current and the voltage can be enlarged; the feedback circuit 508 may be used to measure the electrode implant site impedance and to collect a specific region brain waveform (EEG).
The wireless charging unit 103 is rectified to full-bridge rectification or full-wave rectification, and referring to fig. 5, in the wireless charging schematic diagram, electric energy is output from a high-frequency excitation source 611 outside the body, and is coupled with a receiving coil 601 inside the body through a transmitting coil 610 to receive the electric energy, and then is output to a charging load 602.
The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.

Claims (5)

1. A multi-channel multi-stimulus source deep brain electrical stimulation system is characterized by comprising an implanted nerve stimulator, a program controller, a stimulation electrode and a special operation part, wherein the implanted nerve stimulator is respectively connected with the program controller and the stimulation electrode, and the program controller is also connected with the special operation part;
the implantable neural stimulator comprises an implanted logic control unit, a power management unit, a wireless charging unit, an implanted wireless communication unit, a special ASIC unit and a function protection unit;
the program control instrument comprises a program control logic control unit, a display unit, a status light indicating unit, a key interaction unit, a voice prompt unit, a wireless charging transmitting unit, a storage unit, a program control wireless communication unit, a USB communication unit and a battery charging management unit, wherein,
the implanted logic control unit is respectively connected with the power management unit, the wireless charging unit, the implanted wireless communication unit, the special ASIC unit and the function protection unit and controls the power management unit, the wireless charging unit, the implanted wireless communication unit, the special ASIC unit and the function protection unit;
the power management unit comprises a battery, a power management circuit and a measurement protection circuit, wherein the power management circuit is used for performing voltage stabilization and management on a signal output by the wireless charging unit through rectification, the output of the battery is subjected to voltage boosting or voltage reduction conversion to a required voltage amplitude, and the measurement protection circuit is used for measuring and monitoring the internal resistance of the battery, the voltage of the battery and the output of the battery;
the wireless charging unit receives a wireless charging signal from the outside of the body and rectifies the bidirectional resonance signal to obtain pulsating direct current, and the wireless charging frequency is KHz level or MHz level;
the implanted wireless communication unit is near field coupling communication or far field communication, and bidirectional data transmission between the implanted nerve stimulator and the in-vitro program controller is realized; the wireless communication unit can also adopt radio frequency communication or magnetic element induction;
the special ASIC unit comprises a highly integrated stimulation generating circuit, an electrode configuration circuit and a feedback circuit, wherein the stimulation generating circuit can generate a plurality of voltage sources, a plurality of current sources and a plurality of current wells, the voltage sources, the current sources and the current wells are independent from one another, and the feedback circuit measures the impedance of an electrode implantation part and collects brain waveforms of a designated area;
the function protection unit prevents stimulation signals from overcurrent, overvoltage and frequency upper limit protection and maximum pulse width protection, and prevents excessive charge stimulation to protect the safety of an implanted part; monitoring the total loop current, and pre-judging the short circuit, half short circuit and open circuit conditions of the connection end points;
the program control logic control unit controls the display unit, the state lamp indicating unit, the key interaction unit, the voice prompt unit, the wireless charging transmitting unit, the storage unit, the program control wireless communication unit, the USB communication unit and the battery charging management unit;
the display unit comprises a liquid crystal or a nixie tube, displays an operation menu interface and guides to use the program controller;
the status light indicating unit comprises L ED with a plurality of colors and prompts the charging status;
the key interaction unit comprises a plurality of keys, and the keys are pressed to select the program control function;
the voice prompt unit comprises a buzzer or a voice player and is used for sending out prompt sounds in different states to prompt the operating state;
the wireless charging transmitting unit wirelessly charges a battery in the implanted nerve stimulator and wirelessly charges a short-distance induction type wireless charging technology or magnetic/electric field resonance wireless charging, and the wireless charging frequency is KHz level or MHz level;
the storage unit is an external Flash chip and stores and displays characters and graphic pictures;
the program-controlled wireless communication unit comprises an antenna, a low-power-consumption Bluetooth communication module and/or a near-field coupling communication module and/or a far-field communication module, the near-field coupling communication module comprises pulse frequency modulation or pulse width modulation or digital amplitude modulation or frequency shift keying modulation, and bidirectional data transmission between the implantable neural stimulator and the program-controlled instrument is realized through the antenna; the low-power consumption Bluetooth communication module carries out bidirectional data transmission and control between the program control instrument and the special operation part;
the USB communication unit comprises a USB2.0 or USB3.0 interface, and realizes program control and data transmission of the program control instrument by special control software at a computer end;
the battery charging management unit comprises a charging management circuit and a rechargeable battery, wherein the charging management circuit is used for carrying out charging management on the rechargeable battery and changing the output voltage Buck/Boost of the rechargeable battery to a required voltage amplitude;
the stimulation electrodes are cylindrical, fan-shaped and strip-shaped, and the number of the electrodes is 4-12.
2. The system of claim 1, wherein the implanted logic control unit comprises an MCU or MPU or DSP or FPGA or ASIC.
3. The system of claim 1, wherein the rectification in the wireless charging unit is full-bridge rectification or full-wave rectification.
4. The system of claim 1, wherein the near field coupled communication of the implanted wireless communication unit is pulse frequency modulation or pulse width modulation or digital amplitude modulation or frequency shift keying modulation.
5. The system of claim 1, wherein the stimulus generation circuit of the application specific ASIC unit comprises a logic controller digital interface, a digital decoding circuit, a logic control circuit, respectively connected to the voltage source circuit, the current sink circuit, and the feedback circuit; the stimulation generating circuit can generate a plurality of voltage sources, a plurality of current sources and a plurality of current traps, all the voltage sources, the current sources and the current traps are mutually independent, and amplitude, frequency and pulse width control is carried out according to a digital interface of the logic controller.
CN201921118611.0U 2019-07-17 2019-07-17 Deep brain electrical stimulation system with multiple channels and multiple stimulation sources Active CN211188788U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110327547A (en) * 2019-07-17 2019-10-15 杭州承诺医疗科技有限公司 A kind of lesions located in deep brain system of multichannel thorniness stimulus
CN110433394A (en) * 2019-07-17 2019-11-12 杭州承诺医疗科技有限公司 A kind of brain deep targeting electric stimulation based on multichannel separate current trap

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110327547A (en) * 2019-07-17 2019-10-15 杭州承诺医疗科技有限公司 A kind of lesions located in deep brain system of multichannel thorniness stimulus
CN110433394A (en) * 2019-07-17 2019-11-12 杭州承诺医疗科技有限公司 A kind of brain deep targeting electric stimulation based on multichannel separate current trap

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