CN211156010U

CN211156010U - Implant conveying device and lumen implantation system

Info

Publication number: CN211156010U
Application number: CN201921422787.5U
Authority: CN
Inventors: 彭晴; 刘云云
Original assignee: Microport Neurotech Shanghai Co Ltd
Current assignee: Microport Neurotech Shanghai Co Ltd
Priority date: 2019-08-29
Filing date: 2019-08-29
Publication date: 2020-08-04
Anticipated expiration: 2029-08-29

Abstract

The utility model provides a conveyor and lumen implantation system of implant, including distal end seal wire and near-end seal wire, the near-end of distal end seal wire with the distal end fixed connection of near-end seal wire, the elastic modulus of near-end seal wire is greater than the elastic modulus of distal end seal wire. Because the elastic modulus of the near-end guide wire is greater than that of the far-end guide wire, the pushing performance of the near-end guide wire is good, and the flexibility of the far-end guide wire is good, so that the conveying device for the implant has the pushing performance and the flexibility, and can be better conveyed in a tortuous blood vessel.

Description

Implant conveying device and lumen implantation system

Technical Field

The utility model relates to the technical field of medical equipment, in particular to a conveyor and lumen implantation system of implant.

Background

In recent years, the incidence of vascular diseases has become higher and higher, and related treatment regimens have become popular for research. Among them, intervention treatment is widely accepted, and the intervention treatment usually enters the cardiovascular system through peripheral blood vessels to perform related treatment without performing traumatic thoracotomy or craniotomy.

During the interventional procedure, a stent, a coil or other relevant implanting device is introduced into a blood vessel to reach a lesion by using a delivery device (usually a guide wire). The distance between the puncture point of the conveying device entering the peripheral blood vessel and the lesion part is long, so that the conveying device is required to have good pushing performance, namely certain rigidity; the blood vessels tend to meander near the lesion, and the delivery device must have good flexibility to smoothly pass through these tortuous vessels. However, there is often a certain contradiction between the pushability and the flexibility of the conveying device; increased pushability tends to reduce flexibility, which in turn sacrifices pushability.

Therefore, the improvement of the conveying device of the existing implantation instrument is urgently needed, so that the conveying device has pushing performance and flexibility through the existing processing technology, and the safety and operability of the conveying device are improved.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a conveyor and lumen implantation system of implant to solve the problem that the conveyor and lumen implantation system propelling movement nature and pliability of current implant can not have concurrently.

In order to solve the technical problem, the utility model provides a conveyor of implant, including distal end seal wire and near-end seal wire, the near-end of distal end seal wire with the distal end fixed connection of near-end seal wire, the elastic modulus of near-end seal wire is greater than the elastic modulus of distal end seal wire.

Optionally, the first constant-diameter portion, the transition portion and the second constant-diameter portion are sequentially connected from the proximal end to the distal end, the outer diameters of the first constant-diameter portion and the second constant-diameter portion are uniform, the outer diameter of the first constant-diameter portion is larger than that of the second constant-diameter portion, the outer diameter of the proximal end of the transition portion is equal to that of the first constant-diameter portion, the outer diameter of the distal end of the transition portion is equal to that of the second constant-diameter portion, and the outer diameter of the transition portion gradually decreases from the proximal end to the distal end.

Optionally, the transition portion is disposed on the distal guide wire, and a length ratio of the proximal guide wire to the distal guide wire is 2:1 to 6.5: 1; or the transition part is arranged on the proximal guide wire, and the length ratio of the proximal guide wire to the distal guide wire is 13:1 to 42: 1; or the transition part is arranged at the connection part of the proximal guide wire and the distal guide wire, and the length ratio of the proximal guide wire to the distal guide wire is 6.5:1 to 13: 1.

Optionally, the proximal guide wire is made of stainless steel and the distal guide wire is made of nitinol.

Optionally, the proximal guide wire and the distal guide wire are welded.

Optionally, the distal end face of the proximal guide wire is in a slope shape, the proximal end face of the distal guide wire is in a slope shape, the shape of the distal end face of the proximal guide wire is matched with the shape of the proximal end face of the distal guide wire, the delivery device for an implant further includes at least two welding spots, and the welding spots are disposed between the distal end face of the proximal guide wire and the proximal end face of the distal guide wire.

Optionally, an included angle between the proximal end face of the distal guide wire and the axis of the distal guide wire is a first included angle, an included angle between the distal end face of the proximal guide wire and the axis of the proximal guide wire is a second included angle, the first included angle is equal to the second included angle, and the first included angle and the second included angle are within a range of 45 degrees to 90 degrees.

Optionally, the near-end seal wire includes near-end main part and near-end connecting portion, the distal end of near-end main part with the near-end fixed connection of near-end connecting portion, the far-end seal wire includes far-end main part and far-end connecting portion, the distal end of far-end connecting portion with the near-end fixed connection of far-end main part, near-end connecting portion with the mutual block of far-end connecting portion, just the near-end connecting portion with the mutual welding of far-end connecting portion.

Optionally, the proximal connection portion includes a first concave portion and a first convex portion, the distal connection portion includes a second concave portion and a second convex portion, when the proximal connection portion and the distal connection portion are engaged, the second convex portion is embedded in the first concave portion, and the first convex portion is embedded in the second concave portion.

Optionally, a fixing hole is formed in the distal end face of the proximal end guide wire, the fixing hole extends along the axial direction of the proximal end guide wire, and the proximal end of the distal end guide wire is embedded in the fixing hole.

Optionally, the medical needle further comprises a connecting piece, the proximal end of the connecting piece is fixedly connected with the proximal guide wire, and the distal end of the connecting piece is fixedly connected with the distal guide wire.

Optionally, the medical implant further comprises at least one fixing piece sleeved on the distal guide wire and used for fixing the axial position of the implant, and the fixing piece and the connecting piece are integrated.

Optionally, the proximal guide wire and the distal guide wire are connected by screw thread.

Optionally, the delivery device of the implant further includes a sheath, the sheath is wrapped on the outer peripheral surface of the transition portion and/or the second equal-diameter portion, and the elastic modulus of the sheath is smaller than or equal to that of the distal guide wire.

Optionally, the sheath comprises a polymer tube and/or a helically wound coil.

The utility model also provides a lumen implantation system, including lumen implant, pipe and foretell conveyor of implant, the conveyor of implant movably wears to locate in the pipe, the lumen implant with the detachable connection of distal end liftoff of the conveyor of implant.

The utility model provides a pair of conveyor and lumen implantation system of implant has following beneficial effect:

firstly, the elastic modulus of the near-end guide wire is larger than that of the far-end guide wire, so that the pushing performance of the near-end guide wire is good, the flexibility of the far-end guide wire is good, the conveying device of the implant has the pushing performance and the flexibility, and the conveying device of the implant can be better conveyed in a tortuous blood vessel.

Secondly, as the first equal-diameter part, the transition part and the second equal-diameter part of the implant conveying device are sequentially connected from the near end to the far end, the outer diameter of the first equal-diameter part is larger than that of the second equal-diameter part, the outer diameter of the near end of the transition part is equal to that of the first equal-diameter part, the outer diameter of the far end of the transition part is equal to that of the second equal-diameter part, and the outer diameter of the transition part is gradually reduced from the near end to the far end, the outer diameter of the near end of the implant conveying device is larger than that of the far end, so that the near end has better pushing performance, and the far end has better flexibility; meanwhile, the elastic modulus of the near-end guide wire is larger than that of the far-end guide wire, so that the conveying device of the implant has gradient changes of the outer diameter and the elastic modulus, the pushing performance of the near end is good, and the flexibility of the far end is good.

In addition, the connection position of the near-end guide wire and the far-end guide wire, or the position of the transition part and the connection mode of the near-end guide wire and the far-end guide wire can be set, so that the far-end flexibility of the conveying device for the implant is further improved, the connection strength of the near-end guide wire and the far-end guide wire is improved, the process difficulty, the production cost and the fracture risk are reduced, and the whole safety and the operability of the conveying device are improved.

Drawings

Fig. 1 is a schematic structural view of a delivery device for an implant according to a first embodiment of the present invention;

fig. 2 is a schematic structural view of a delivery device for an implant according to a second embodiment of the present invention;

fig. 3 is a schematic structural view of a delivery device for an implant according to a third embodiment of the present invention;

fig. 4 is a schematic structural view of a delivery device for an implant according to a fourth embodiment of the present invention;

fig. 5 is a schematic structural view of a delivery device for an implant according to a fifth embodiment of the present invention;

fig. 6 is a schematic structural view of a delivery device for an implant according to another embodiment of the present invention;

fig. 7 is a schematic structural view of a delivery device for an implant according to a sixth embodiment of the present invention.

Description of reference numerals:

example one

110-a distal guidewire; 111-first stage; 112-a second segment; 113-a third section;

120-a proximal guidewire;

130-a first angle;

140-a second included angle;

150-head;

161-a first fixture; 162-a second securing member;

170-coil.

Example two

210-a distal guidewire; 211-a distal body; 212-first section; 213-second stage; 214-third section; 215-distal connection; 216-a second recess; 217-a second projection;

220-a proximal guidewire; 221-a proximal body; 222-a proximal connection; 223-a first recess; 224-a first projection;

230-a head;

241-a first fixing piece; 242-a second fixture;

250-coil.

EXAMPLE III

310-a distal guidewire;

320-a proximal guidewire; 321-a proximal body; 322-constant diameter section; 323-a reducing section; 324-a fixation hole;

330-a head;

341-first fixing member; 342-a second mount;

350-coil.

Example four

410-a distal guidewire;

420-a proximal guidewire;

430-a connector;

440-a head;

451-a first fastener; 452-a second fixture;

460-coil.

EXAMPLE five

510-a distal guidewire;

520-a proximal guidewire; 521-a first diameter section; 522-a variable diameter section; 523-second equal-diameter section;

530-a connector;

540-head;

551-first fixing piece; 552-a second fastener;

560-coil.

EXAMPLE six

610-a distal guidewire; 611-first section; 612-a second section; 613-third section;

620-a proximal guidewire; 622-screw hole;

630-a header;

641-a first fastener; 642-a second fixture;

650-coil.

Detailed Description

As described in the background, the delivery devices for the existing implants have the problem that the pushability and the flexibility cannot be combined.

The applicant has found that the delivery means of the existing implants are mostly of one-piece construction and that the delivery means of the implant is made of only one material, such as stainless steel, from the proximal end to the distal end. The proximal end of the delivery device for such implants usually has sufficient pushability, but the flexibility of the distal end is not sufficient. In actual use, the bending (Kink) phenomenon is easy to occur, the blood vessel is easy to be damaged, the operability is poor, and the using requirements of doctors cannot be met. Further, the applicant found that if a proximal guide wire with better pushability and a distal guide wire with better flexibility can be spliced together, the implant delivery device can have good pushability and flexibility.

The applicant has also found that the flexibility of the distal end of the delivery device of the implant can be further improved if a proximal guide wire having better pushability and a distal guide wire having better flexibility can be spliced together while adjusting the outer diameter of the delivery device of the spliced implant. For example, the outer diameter of the delivery device of the implant is tapered from the distal end to the proximal end.

However, the process difficulty of splicing two extremely fine guide wires with different flexibility or gradually reducing the outer diameter of the implant delivery device from the proximal end to the distal end is high, and the actual effect is not ideal. The conveying device for the implant, which is processed by the existing process and equipment, has the problems that the length of the reducing section is insufficient or the reducing section cannot be gently reduced, the outer diameter of the far end cannot meet the theoretical requirement, the joint strength of splicing parts made of different materials is insufficient, and the conveying device is easy to break in the use process.

Based on this, the applicant provides a delivery device for an implant, which includes a distal guide wire and a proximal guide wire, wherein the proximal end of the distal guide wire is fixedly connected with the distal end of the proximal guide wire, and the elastic modulus of the proximal guide wire is different from that of the distal guide wire, and the elastic modulus of the proximal guide wire is greater than that of the distal guide wire, so that the proximal guide wire has good pushability and the distal guide wire has good flexibility, and the delivery device for an implant has both pushability and flexibility.

Correspondingly, the utility model discloses still provide a lumen implantation system, lumen implantation system includes lumen implant, pipe and foretell implant's conveyor, and the conveyor of implant is movably worn to locate in the pipe, and the detachable connection of distal end of the conveyor of lumen implant and implant.

The delivery device and the lumen implantation system of the present invention will be described in further detail with reference to the accompanying drawings and specific embodiments. It should be noted that the drawings are in simplified form and are not to precise scale, and are provided for convenience and clarity in order to facilitate the description of the embodiments of the present invention.

Example one

The present embodiments provide a delivery device for an implant. Referring to fig. 1, fig. 1 is a schematic structural diagram of a delivery device for an implant according to a first embodiment of the present invention, the delivery device for an implant includes a distal guide wire 110 and a proximal guide wire 120, a proximal end of the distal guide wire 110 is fixedly connected to a distal end of the proximal guide wire 120, and an elastic modulus of the proximal guide wire 120 is greater than an elastic modulus of the distal guide wire 110. Because the elastic modulus of the proximal guide wire 120 is greater than that of the distal guide wire 110, the pushing performance of the proximal guide wire 120 is good, and the flexibility of the distal guide wire 110 is good, so that the implant delivery device has both pushing performance and flexibility.

Wherein the outer diameter of the delivery device of the implant decreases from the proximal end to the distal end.

The proximal guidewire 120 is made of stainless steel and the distal guidewire 110 is made of nitinol.

The proximal guide wire 120 and the distal guide wire 110 are fixedly connected by welding. The applicant finds that the proximal guide wire 120 made of stainless steel and the distal guide wire 110 made of nitinol in the present embodiment can achieve both good proximal pushability and distal flexibility, and can achieve high-strength connection through a relatively simple welding process, which is difficult to achieve if different materials are used for splicing.

The distal end face of the proximal guide wire 120 is in a slope shape, the proximal end face of the distal guide wire 110 is in a slope shape, the shape of the distal end face of the proximal guide wire 120 is matched with the shape of the proximal end face of the distal guide wire 110, and the distal end face of the proximal guide wire 120 and the proximal end face of the distal guide wire 110 are joined with each other in a welding manner. In some embodiments, there are at least two welding spots between the distal end surface of the proximal guide wire 120 and the proximal end surface of the distal guide wire 110 to increase the connection strength between the proximal guide wire 120 and the distal guide wire 110, and these welding spots can be distributed at any position of the two end surfaces; preferably, the welding spots may be distributed on the edges of the two end faces, i.e. on the outer circumferential surface of the joint between the two end faces. Since the distal end surface of the proximal guide wire 120 and the proximal end surface of the distal guide wire 110 are sloped, the number of welding spots between the distal end surface of the proximal guide wire 120 and the proximal end surface of the distal guide wire 110 can be increased, or the number of welding spots provided on the outer peripheral surface of the joint between the two end surfaces can be increased, thereby improving the welding strength between the proximal guide wire 120 and the distal guide wire 110.

Wherein, the welding mode includes but not limited to: laser welding, resistance welding, and pulse welding.

As shown in fig. 1, the distal end face of the proximal guide wire 120 is welded to the proximal end face of the distal guide wire 110.

Specifically, an included angle between the proximal end face of the distal guide wire 110 and the axis of the distal guide wire 110 is a first included angle 130, an included angle between the distal end face of the proximal guide wire 120 and the axis of the proximal guide wire 120 is a second included angle 140, and the first included angle 130 is equal to the second included angle 140. The first included angle 130 and the second included angle 140 are greater than 0 ° and equal to or less than 90 °.

Preferably, the first included angle 130 and the second included angle 140 are in the range of 45 ° to 90 °, so that not only a certain slope is provided to increase the area for arranging the welding point, but also the process is easier to implement (if the slope is too slow, the end face is too long, and the end face is very thin and easy to break near the end point), and the problem of low strength of the welding point caused by welding two materials can be solved.

The delivery device of the implant includes a first major diameter portion, a transition portion, and a second major diameter portion. The first equal-diameter part, the transition part and the second equal-diameter part are sequentially connected from the near end to the far end, the outer diameter of the first equal-diameter part is larger than that of the second equal-diameter part, the outer diameter of the near end of the transition part is equal to that of the first equal-diameter part, the outer diameter of the far end of the transition part is equal to that of the second equal-diameter part, and the outer diameter of the transition part is gradually reduced from the near end to the far end. In this embodiment, the transition portion is disposed on the distal guidewire.

In this embodiment, because the elastic modulus of near-end seal wire is greater than the elastic modulus of distal end seal wire, just the distal end seal wire has the transition portion of reducing, and the conveyor through making the implant possesses the gradient change of external diameter and elastic modulus simultaneously, can realize more effectively that the conveyor of implant's the part that is close to the distal end has better pliability, and the part that is close to the distal end has better propelling movement nature, has better transition between the both ends, and the processing technology degree of difficulty is low, can effectively promote the conveyor's of implant whole maneuverability.

The proximal guide wire 120 is cylindrical and has a diameter of 0.2-0.7 mm.

The distal guide wire 110 comprises a first section 111, a second section 112 and a third section 113, wherein the first section 111, the second section 112 and the third section 113 are sequentially connected from the proximal end to the distal end. Wherein the proximal end of the first segment 111 is connected to the proximal guidewire 120. The proximal end face of the distal guide wire 110 and the proximal end face of the first segment 111 are the same end face.

The first segment 111 is cylindrical and has a proximal end connected to a proximal guidewire 120. The diameter of the first segment 111 is equal to the diameter of the proximal guidewire 120, for example 0.2-0.7mm, and the length thereof may be 10-300 mm.

The third section 113 is also cylindrical and has a smaller diameter than the first section 111, for example: is 0.06-0.15mm, and its length can be 20-80 mm.

The second segment 112 is located between the first segment 111 and the third segment 113, and has a proximal end connected to the first segment 111 and a distal end connected to the third segment 113. The second section 112 is in a circular truncated cone shape, the diameter of the second section 112 gradually decreases from the proximal end to the distal end, the diameter of the proximal end is equal to that of the first section 111, and the diameter of the distal end is equal to that of the third section 113. Wherein the length of the second section 112 may be 150-500 mm.

Wherein the second section 112 is the transition portion. In other embodiments of the present invention, the transition portion is not limited to be circular truncated cone, but may be other shapes, for example, a plurality of circular truncated cones with different tapers are connected in the axial direction, or include an equal diameter portion and a plurality of reducing portions.

Further, the length of the proximal guide wire 120 may be 1400-1900mm, and the length of the distal guide wire 110 may be 300-700mm, so that the length ratio of the proximal guide wire 120 to the distal guide wire 110 is 2:1 to 6.5: 1. By arranging the transition part on the distal guide wire and further arranging the connection position of the proximal guide wire and the distal guide wire, the pushing performance and the flexibility of the delivery device of the implant can be further adjusted to realize gradual gradient change from the proximal end to the distal end, and the overall operability of the delivery device of the implant can reach a state close to an ideal state on the premise of ensuring safety and not increasing process difficulty and cost.

The implant delivery device further comprises a head 150, wherein the head 150 is fixedly connected with the distal end of the distal guide wire 110, in particular, the distal end of the third segment 113 in the distal guide wire 110. The outer surface of the head 150 is smooth to avoid the head 150 from scratching the blood vessel, while improving the pushability of the delivery device of the implant.

The implant delivery device further comprises a first fixing piece 161 and a second fixing piece 162, wherein the first fixing piece 161 and the second fixing piece 162 are sequentially sleeved on the distal guide wire 110 from the proximal end to the distal end and are respectively and fixedly connected with the distal guide wire 110.

The first fastener 161 and the second fastener 162 are used to axially fix the implant on the distal guide wire 110. The implant may be a stent, a coil, a vascular occlusion device, or the like. For example: the axial relative position of the stent and the delivery device of the implant can be fixed by placing a catch (e.g., a developing section of the stent) at one end of the stent between the first fixing member 161 and the second fixing member 162.

In addition, the first and

second fixtures

161 and 162 may be used for visualization so that a doctor can know the position of the stent or the coil. In this case, the first fixing member 161 and the second fixing member 162 are made of a developing material, for example: platinum, tungsten, iridium, platinum tungsten, platinum iridium, or the like.

The implant delivery device further includes a sheath having a modulus of elasticity less than or equal to the modulus of elasticity of the distal guidewire 110. In this embodiment, the sheath covers an outer peripheral surface of a distal end of the delivery device of the implant, and specifically covers a portion of the first equal-diameter portion, the transition portion, and a portion of the second equal-diameter portion. So can strengthen the conveyor cladding of implant has the partial intensity of sheath, through increasing the external diameter, strengthens the anti ability of buckling of distal end seal wire, and the power conduction is better, promotes the propelling movement performance, does not have the influence to the pliability simultaneously almost. Specifically, as shown in fig. 1, the sheath is a spiral-wound coil 170, and the coil 170 is wrapped around a portion of the outer circumferential surface of the first section 111 near the distal end of the first section 111, a portion of the outer circumferential surface of the second section 112, and a portion of the outer circumferential surface of the proximal end of the third section 113.

The distal end of the coil 170 is fixedly connected to the first fixing member 161. In other embodiments, the distal end of the coil 170 is spaced apart from the first mount 161.

The outer diameter of the coil 170 varies with the diameter of the portion it surrounds. Specifically, the outer diameter of the coil 170 may vary in the range of 0.11 to 0.80mm, and the wire diameter of the coil 170 may be 0.001 to 0.002 inch. The wire diameter of the coil 170 may be uniform or may be tapered from the proximal end to the distal end.

The length of the coil 170 may be 300-700 mm.

In other embodiments of the present invention, the sheath may also be a polymer tube, or the sheath may include a coil and at least one polymer tube. For example, the sheath comprises a coil 170 and a polymer tube, the polymer tube is sleeved outside the coil 170, and the coil 170 is at least spirally wound on the transition part and the proximal part of the second diameter part of the implant delivery device; for another example, the sheath includes a coil 170 and two polymer tubes, one of which is sleeved over a distal portion of the first constant diameter portion, a transition portion, and a proximal portion of the second constant diameter portion of the delivery device of the implant, the coil 170 being helically wound around the exterior of the polymer tube, and the other of which is sleeved over the exterior of the coil 170. Wherein, the material of the polymer tube is preferably one or a combination of more of polytetrafluoroethylene, polyethylene terephthalate or polyolefin; the material of the coil 170 is preferably one or more of nitinol, platinum iridium, platinum tungsten, stainless steel, etc.

The embodiment also provides a lumen implantation system, which comprises a lumen implant, a catheter and the implant delivery device, wherein the implant delivery device is movably arranged in the catheter in a penetrating way, and the lumen implant is detachably connected with the distal end of the implant delivery device. The implant delivery device comprises a distal guide wire and a proximal guide wire, wherein the proximal end of the distal guide wire is fixedly connected with the distal end of the proximal guide wire, and the elastic modulus of the proximal guide wire is greater than that of the distal guide wire.

Example two

The present embodiment provides a delivery device for an implant, which is different from the delivery device for an implant in the first embodiment in that the structure of the junction between the proximal guide wire and the distal guide wire is different in the present embodiment.

Referring to fig. 2, fig. 2 is a schematic structural diagram of a delivery device for an implant according to a second embodiment of the present invention, in which the proximal guidewire 220 includes a proximal main body 221 and a proximal connecting portion 222, and a distal end of the proximal main body 221 is fixedly connected to a proximal end of the proximal connecting portion 222. The distal guide wire 210 includes a distal main body 211 and a distal connecting portion 215, and a distal end of the distal connecting portion 215 is fixedly connected to a proximal end of the distal main body 211. The proximal connecting portion 222 and the distal connecting portion 215 are engaged with each other to limit the proximal guide wire 220 and the distal guide wire 210 from being separated from each other in the axial direction. The proximal connection 222 and the distal connection 215 are welded to each other. In this way, the proximal guide wire 220 and the distal guide wire 210 can be fixedly connected by the engagement of the proximal connecting portion 222 and the distal connecting portion 215 and the mutual welding of the proximal connecting portion 222 and the distal connecting portion 215. Due to the clamping of the proximal connecting portion 222 and the distal connecting portion 215, the range of welding points can be increased, the connecting strength is enhanced, due to the clamping of the proximal connecting portion 222 and the distal connecting portion 215, the axial connecting strength can be increased, the axial connection can be maintained even if welding fails, and the connecting reliability of the proximal guide wire 220 and the distal guide wire 210 can be improved. Wherein, the welding manner of the proximal connecting portion 222 and the distal connecting portion 215 includes but is not limited to: laser welding, resistance welding, pulse welding.

Referring to fig. 2, the proximal connection portion 222 includes a first concave portion 223 and a first convex portion 224, the distal connection portion 215 includes a second concave portion 216 and a second convex portion 217, when the proximal connection portion 222 and the distal connection portion 215 are engaged, the second convex portion 217 is embedded in the first concave portion 223, and the first convex portion 224 is embedded in the second concave portion 216. In other embodiments, the proximal connection portion 222 and the distal connection portion 215 may have other structures as long as the proximal guide wire 220 and the distal guide wire 210 are restricted from being axially separated from each other. Of course, the proximal connecting portion 222 and the distal connecting portion 215 may also limit the separation of the proximal guide wire 220 and the distal guide wire 210 in the radial direction while limiting the separation of the proximal guide wire 220 and the distal guide wire 210 in the axial direction, which is not limited by the present invention.

In this embodiment, the proximal body 221 and the proximal connecting portion 222 are integrally provided. The distal end body 211 and the distal end connecting portion 215 are integrally provided.

The proximal body 221 is cylindrical and may have a diameter of 0.2-0.7 mm.

The distal body 211 comprises a first section 212, a second section 213 and a third section 214, wherein the first section 212, the second section 213 and the third section 214 are connected in sequence from the proximal end to the distal end. Wherein the proximal end of the first segment 212 is connected to the proximal guidewire 220. The proximal end face of the distal guidewire 210 is the same as the proximal end face of the first segment 212.

The first section 212 is cylindrical and has a proximal end connected to a proximal guidewire 220. The diameter of the first segment 212 is equal to the diameter of the proximal guidewire 220, e.g., 0.2-0.7mm, and the length thereof may be 10-300 mm.

The third section 214 is also cylindrical and has a diameter smaller than the diameter of the first section 212, for example: is 0.06-0.15mm, and its length can be 20-80 mm.

The second segment 213 is located between the first segment 212 and the third segment 214, and has a proximal end connected to the first segment 212 and a distal end connected to the third segment 214. The second section 213 is in the shape of a circular truncated cone, the diameter of the second section 213 decreases gradually from the proximal end to the distal end, the diameter of the proximal end is equal to the diameter of the first section 212, and the diameter of the distal end is equal to the diameter of the third section 214. Wherein, the length of the second segment 213 can be 150-500 mm.

Wherein the second section 213 is the transition portion.

Preferably, the proximal connecting portion 222 and the distal connecting portion 215 are clamped to each other to form a cylindrical shape, and an outer diameter of the proximal connecting portion 222 and the distal connecting portion 215 after being clamped to each other is equal to an outer diameter of the proximal body 221 and is also equal to an outer diameter of the first section 212.

The implant delivery device further comprises a head 230, a first fastener 241, a second fastener 242, and a coil 250. The size, structure, function and connection between the head 230, the first fastener 241, the second fastener 242 and the coil 250 and between the head, the first fastener, the second fastener and the coil 220 and the coil 210 are similar to those of the implant delivery device in the first embodiment, and therefore, the detailed description is omitted.

The embodiment also provides a lumen implantation system, which comprises a lumen implant, a catheter and the implant delivery device, wherein the implant delivery device is movably arranged in the catheter in a penetrating way, and the lumen implant is detachably connected with the distal end of the implant delivery device.

EXAMPLE III

The present embodiment provides a delivery device for an implant, which is different from the delivery device for an implant in the first embodiment mainly in that, in the present embodiment, the position and the structure of the junction of the proximal guide wire and the distal guide wire are different.

Referring to fig. 3, fig. 3 is a schematic structural diagram of a delivery device of an implant according to a third embodiment of the present invention, the delivery device of the implant includes a distal guide wire 310 and a proximal guide wire 320, a proximal end of the distal guide wire 310 is fixedly connected to a distal end of the proximal guide wire 320, and an elastic modulus of the proximal guide wire 320 is greater than an elastic modulus of the distal guide wire 310. Because the elastic modulus of the proximal guide wire 320 is greater than that of the distal guide wire 310, the pushing performance of the proximal guide wire 320 is good, and the flexibility of the distal guide wire 310 is good, so that the implant delivery device has both pushing performance and flexibility.

The proximal guidewire 320 is made of stainless steel and the distal guidewire 310 is made of nitinol.

The proximal guidewire 320 may be 1400-1900mm in length and the distal guidewire 310 may be 300-700mm in length.

The proximal guide wire 320 and the distal guide wire 310 are fixedly connected by welding.

The distal end face of the proximal guide wire 320 is provided with a fixing hole 324, the fixing hole 324 extends along the axial direction of the proximal guide wire 320, and the proximal end of the distal guide wire 310 is embedded in the fixing hole 324. In this embodiment, the proximal end of the distal guide wire 310 embedded in the fixing hole 324 and the proximal guide wire 320 can be fixedly connected by welding, for example, a welding point can be arranged along the annular seam between the fixing hole 324 and the distal guide wire 310 to weld the two. Wherein, the welding mode includes but not limited to: laser welding, resistance welding, pulse welding.

The delivery device of the implant includes a first major diameter portion, a transition portion, and a second major diameter portion. The first equal-diameter part, the transition part and the second equal-diameter part are sequentially connected from the near end to the far end, the outer diameter of the first equal-diameter part is larger than that of the second equal-diameter part, the outer diameter of the near end of the transition part is equal to that of the first equal-diameter part, the outer diameter of the far end of the transition part is equal to that of the second equal-diameter part, and the outer diameter of the transition part is gradually reduced from the near end to the far end. In this embodiment, the transition portion is disposed at a junction of the proximal guide wire and the distal guide wire.

The proximal guidewire 320 includes a proximal body 321. The proximal body 321 includes a constant diameter section 322 and a variable diameter section 323, and the constant diameter section 322 and the variable diameter section 323 are sequentially disposed from a proximal end to a distal end. The outer surface of the equal-diameter section 322 is cylindrical, the length can be 1000-1600mm, and the diameter can be 0.2-0.7 mm. The outer surface 323 of the variable diameter section is in a circular truncated cone shape, the outer diameter of the variable diameter section 323 gradually decreases from the proximal end to the distal end, the length of the variable diameter section 323 can be 20-800mm, the maximum diameter of the variable diameter section 323 is equal to the diameter of the constant diameter section 322, and the minimum diameter of the variable diameter section 323 can be 0.06-0.22 mm. The diameter of the fixing hole 324 may be 0.06-0.22mm, and the length of the fixing hole 324 may be 10-600 mm.

Wherein, the variable diameter section 323 is the transition portion.

The distal guide wire 310 has a cylindrical shape, and the length of the distal guide wire 310 may be 300mm and 700 mm. The diameter of the distal guidewire 310 matches the diameter of the fixation hole 324 in the proximal guidewire 320, such as 0.06-0.22mm, or such as 0.04-0.2mm, to allow the proximal end of the distal guidewire 310 to be inserted into the fixation hole 324.

In this embodiment, the ratio of the lengths of the proximal guidewire 320 and the distal guidewire 310 is 6.5:1 to 13: 1. In this way, by disposing the transition portion at the junction of the proximal guide wire 320 and the distal guide wire 310 and further disposing the length ratio of the proximal guide wire 320 and the distal guide wire 310, the pushability and flexibility of the delivery device of the implant can be further adjusted to realize a gradual gradient change from the proximal end to the distal end, so as to achieve a near-ideal operability of the delivery device of the implant on the premise of ensuring safety and not increasing process difficulty and cost.

Further, an inner thread may be provided on an inner wall of the fixing hole 324, and an outer thread matching the inner thread may be provided on a portion of the distal guide wire 310 near the proximal end, so as to fixedly connect the proximal guide wire 320 and the distal guide wire 310 by means of a threaded connection. In other embodiments, the proximal guide wire 320 and the distal guide wire 310 may be fixedly connected only by a threaded connection, and the proximal guide wire 320 and the distal guide wire 310 are not fixedly connected by welding, or the proximal guide wire 320 and the distal guide wire 310 may be fixedly connected only by welding, and the proximal guide wire 320 and the distal guide wire 310 are not fixedly connected by a threaded connection.

Preferably, the minimum outer diameter of the tapered section 323 of the proximal guidewire 320 is equal to or slightly larger than the outer diameter of the distal guidewire 310. Thus, when the distal guide wire 310 is inserted into the fixing hole 324, the outer surface of the delivery device of the implant can be smoothly transited, and the outer diameter of the delivery device of the implant is not suddenly reduced, so that the delivery device of the implant can be integrally similar to a streamline shape, and the delivery device of the implant can be smoothly advanced in the blood vessel.

The delivery device of the implant further comprises a head 330, wherein the head 330 is fixedly connected with the distal end of the distal guide wire 310. The outer surface of the head 330 is smooth to avoid the head 330 from scratching the blood vessel, while improving pushability of the delivery device of the implant.

The implant delivery device further comprises a first fixing member 341 and a second fixing member 342, the first fixing member 341 and the second fixing member 342 are sequentially sleeved on the distal guide wire 310 from the proximal end to the distal end, and the first fixing member 341 and the second fixing member 342 are respectively and fixedly connected with the distal guide wire 310.

The first fixing member 341 and the second fixing member 342 are used to fix the implant on the distal guide wire 310.

The implant may be a stent, a coil, a vascular occlusion device, or the like. For example: the axial relative position of the stent and the delivery device of the implant can be fixed by placing a catch (e.g., a developing section of the stent) at one end of the stent between the first fixing member 341 and the second fixing member 342.

In addition, the first fixing member 341 and the second fixing member 342 may be used for visualization so that a doctor can know the position of the stent or the coil. In this case, the first fixing member 341 and the second fixing member 342 are made of a developing material, for example: platinum, tungsten, iridium, platinum tungsten, platinum iridium, or the like.

The delivery device of the implant further comprises a coil 350, wherein the coil 350 is coated on the outer peripheral surfaces of part of the first equal-diameter part, the transition part and part of the second equal-diameter part, namely the outer peripheral surfaces of part of the equal-diameter section 322, the reducing section 323 and part of the distal guide wire 310, so that the strength of the portion, coated with the coil 350, of the delivery device of the implant can be enhanced while the flexibility is not influenced, the strength of the joint of the proximal guide wire 320 and the distal guide wire 310 and the pushing performance of the distal guide wire 310 are enhanced, and further the pushing performance, the ovality resistance and the bending resistance of the whole delivery device of the implant are enhanced. In other embodiments, the coil 350 may be replaced by a polymer tube, or the coil 350 may be wrapped by a polymer tube, and used as a sheath wrapped on the distal portion of the delivery device of the implant, where the elastic modulus of the sheath is less than or equal to the elastic modulus of the distal guide wire 310, so as to improve the bending resistance of the distal portion of the delivery device of the implant without affecting the flexibility of the distal portion.

The distal end of the coil 350 is fixedly connected to the first fixing member 341. In other embodiments, the distal end of the coil 350 is separate from the first anchor 341.

The outer diameter of the coil 350 varies with the diameter of the portion it surrounds. Specifically, the outer diameter of the coil 350 may vary from 0.11 to 1.97mm, and the wire diameter of the coil 350 may be 0.001 to 0.0025 inch. The length of the coil 350 may be 200 and 800 mm.

Example four

The present embodiment provides a delivery device for an implant, which is different from the delivery device for an implant in the first embodiment mainly in that, in the present embodiment, the structure of the junction between the proximal guide wire 420 and the distal guide wire 410 is different.

Referring to fig. 4, fig. 4 is a schematic structural diagram of a delivery device of an implant in a fourth embodiment of the present invention, the delivery device of the implant includes a distal guide wire 410 and a proximal guide wire 420, a proximal end of the distal guide wire 410 is fixedly connected to a distal end of the proximal guide wire 420, and an elastic modulus of the proximal guide wire 420 is greater than an elastic modulus of the distal guide wire 410. Because the elastic modulus of the proximal guide wire 420 is greater than that of the distal guide wire 410, the pushing performance of the proximal guide wire 420 is good, and the flexibility of the distal guide wire 410 is good, so that the implant delivery device has both pushing performance and flexibility.

The proximal guidewire 420 is made of stainless steel and the distal guidewire 410 is made of nitinol.

The proximal guidewire 420 may be 1400-1900mm in length and the distal guidewire 410 may be 300-700mm in length.

The delivery device of the implant further comprises a connecting piece 430, the proximal end of the connecting piece 430 is fixedly connected with the proximal guide wire 420, and the distal end of the connecting piece 430 is fixedly connected with the distal guide wire 410, so that the connecting strength of the proximal guide wire 420 and the distal guide wire 410 can be improved, and the risk of disconnection of the delivery device of the implant is reduced.

Specifically, as shown in fig. 4, the connecting member 430 is in the shape of a hollow circular tube, the connecting member 430 is wrapped on the outer peripheral surface of the proximal guide wire 420 close to the distal end, and is wrapped on the outer peripheral surface of the distal guide wire 410 close to the proximal end, and the connecting member 430 is respectively and fixedly connected to the proximal guide wire 420 and the distal guide wire 410.

In this embodiment, the connecting member 430 is fixedly connected to the proximal guide wire 420 by welding, and the connecting member 430 is fixedly connected to the distal guide wire 410 by welding, so that the proximal guide wire 420 is fixedly connected to the distal guide wire 410. The welding method includes, but is not limited to: laser welding, resistance welding, pulse welding. In addition, the connecting member 430 and the proximal guide wire 420 can be fixedly connected in other manners, and the connecting member 430 and the distal guide wire 410 can be fixedly connected in other manners, for example, by welding with another material which is more easily melted with stainless steel and nickel titanium respectively, so that the welding strength is higher. As shown in fig. 4, the diameters of the proximal guide wire 420 and the distal guide wire 410 are equal, and a seam is formed between the distal end surface of the proximal guide wire 420 and the proximal end surface of the distal guide wire 410.

Preferably, the connection member 430 may be made of a stainless material. The length of the connection member 430 may be 1-20mm, and the thickness of the tube wall of the connection member 430 is 0.01-0.05 mm.

The shape, length, material and structure of the proximal guide wire 420 are the same as the proximal guide wire 420 in the first embodiment, and the shape, length, material and structure of the distal guide wire 410 are the same as the distal guide wire 410 in the first embodiment, which are not described herein again.

The implant delivery device further comprises a head 440, a first mount 451, a second mount 452, and a coil 460. The size, structure, function and connection between the head 440, the first fastener 451, the second fastener 452 and the coil 460 are similar to those of the implant delivery device in the first embodiment, and the description thereof is omitted.

EXAMPLE five

The present embodiments provide a delivery device for an implant. The essential differences between the delivery device of the implant in this embodiment and the other embodiments are: the transition portion is disposed on the proximal guidewire and the junction of the proximal guidewire and the distal guidewire is disposed on the second major diameter portion.

Specifically, referring to fig. 5, fig. 5 is a schematic structural diagram of a delivery device of an implant according to a fifth embodiment of the present invention, the delivery device of the implant includes a distal guide wire 510 and a proximal guide wire 520, a proximal end of the distal guide wire 510 is fixedly connected to a distal end of the proximal guide wire 520, and an elastic modulus of the proximal guide wire 520 is greater than an elastic modulus of the distal guide wire 510. Because the elastic modulus of the proximal guide wire 520 is greater than that of the distal guide wire 510, the pushing performance of the proximal guide wire 520 is good, and the flexibility of the distal guide wire 510 is good, so that the implant delivery device has both pushing performance and flexibility.

The proximal guidewire 520 is made of stainless steel and the distal guidewire 510 is made of nitinol.

The proximal guidewire 520 can be 1950-2050mm in length and the distal guidewire 510 can be 50-150mm in length.

When the transition portion is disposed on the proximal guide wire, the length ratio of the proximal guide wire 520 to the distal guide wire 510 may be 13:1 to 42:1, so as to further adjust the pushability and flexibility of the delivery device of the implant to achieve a gradual gradient change from the proximal end to the distal end, and to achieve a near-ideal operability of the delivery device of the implant without increasing the process difficulty and cost while ensuring safety.

The delivery device of the implant further comprises a connecting member 530, wherein the proximal end of the connecting member 530 is fixedly connected with the proximal guide wire 520, and the distal end of the connecting member 530 is fixedly connected with the distal guide wire 510.

Specifically, as shown in fig. 5, the connecting member 530 is in the shape of a hollow circular tube, the connecting member 530 is wrapped on the outer peripheral surface of the proximal guide wire 520 near the distal end and wrapped on the outer peripheral surface of the distal guide wire 510 near the proximal end, and the connecting member 530 is respectively fixedly connected to the proximal guide wire 520 and the distal guide wire 510.

In this embodiment, the connecting member 530 is fixedly connected to the proximal guide wire 520 by welding, and the connecting member 530 is fixedly connected to the distal guide wire 510 by welding, so that the proximal guide wire 520 is fixedly connected to the distal guide wire 510. The welding method includes, but is not limited to: laser welding, resistance welding, pulse welding.

Preferably, the connection member 530 may be made of a stainless material. The length of the connector 530 may be 1-20mm, and the thickness of the pipe wall of the connector 530 is 0.01-0.05 mm.

The delivery device of the implant includes a first major diameter portion, a transition portion, and a second major diameter portion. The first equal-diameter part, the transition part and the second equal-diameter part are sequentially connected from the near end to the far end, the outer diameter of the first equal-diameter part is larger than that of the second equal-diameter part, the outer diameter of the near end of the transition part is equal to that of the first equal-diameter part, the outer diameter of the far end of the transition part is equal to that of the second equal-diameter part, and the outer diameter of the transition part is gradually reduced from the near end to the far end. In this embodiment, the transition portion is disposed on the proximal guidewire.

The proximal guide wire 520 includes a first diameter-variable section 521, a diameter-variable section 522 and a second diameter-variable section 523, and the first diameter-variable section 521, the diameter-variable section 522 and the second diameter-variable section 523 are sequentially arranged from a proximal end to a distal end.

Wherein, the variable diameter section 323 is the transition portion.

Preferably, the length of the first equal-diameter section 521 can be 1400-1900mm, and the diameter of the first equal-diameter section 521 can be 0.2-0.7 mm. The length of the variable diameter section 522 can be 150-700mm, the maximum diameter of the variable diameter section 522 is equal to the diameter of the first equal diameter section 521, and the minimum diameter of the variable diameter section 522 is equal to the diameter of the second equal diameter section 523. The length of the second radiused section 523 may be 200 and 500mm, and the diameter of the second radiused section 523 may be 0.06-0.18 mm.

The distal guide wire 510 is cylindrical, the length of the distal guide wire 510 may be 50-150mm, and the diameter of the distal guide wire 510 is equal to the diameter of the second equal-diameter segment 523 of the proximal guide wire 520. The proximal end of the distal guidewire 510 interfaces with the distal end of the second radiused segment 523 to form a seam.

The delivery device of the implant further comprises a head 540, the head 540 being fixedly connected to the distal end of the distal guide wire 510. The outer surface of the head 540 is smooth to avoid the head 540 from scratching the blood vessel, while improving pushability of the delivery device of the implant.

The implant delivery device further comprises a first fixing part 551 and a second fixing part 552, the first fixing part 551 and the second fixing part 552 are sequentially sleeved on the distal guide wire 510 from the proximal end to the distal end, and the first fixing part 551 and the second fixing part 552 are respectively and fixedly connected with the distal guide wire 510. In other embodiments, the delivery device of the implant further comprises a plurality of fasteners, which is not limited by the present invention.

The first and

second anchors

551, 552 are used to secure an implant to the distal guidewire 510. The implant may be a stent, a coil, a vascular occlusion device, or the like. For example: the axial relative position of the stent and the delivery device of the implant can be fixed by placing a catch at one end of the stent (e.g., the developing section of the stent) between the first fixing member 551 and the second fixing member 552. In addition, the first and

second fixtures

551 and 552 may also be used for visualization to allow a physician to know the location of the stent or coil. In this case, the first and

second fixtures

551 and 552 are made of developing materials, for example: platinum, tungsten, iridium, platinum tungsten, platinum iridium, or the like.

In other embodiments, the first fastener 551 and the second fastener 552 may also be disposed over the proximal guidewire 520. In another embodiment, referring to fig. 6, fig. 6 is a schematic structural diagram of a delivery device for an implant according to another embodiment of the present invention, the first fixing member 551 can be used as a connecting member 530 for connecting the proximal wire 520 and the distal wire 510, i.e., the first fixing member 551 and the connecting member 530 are integrally disposed. In this case, the length of the first fixing member 551 may be 0.1 to 1mm, and the thickness of the tube wall of the first fixing member 551 is 0.05 to 0.2 mm. In other embodiments, the second fixing element 552 may also serve as the connecting element 530 for connecting the proximal guide wire 520 and the distal guide wire 510, i.e., the second fixing element 552 is integrally provided with the connecting element 530.

The delivery device of the implant further includes a coil 560, the coil 560 is wrapped on the outer circumferential surface of the proximal guide wire 520, specifically, the coil 560 may be wrapped on a portion of the first equal-diameter portion, the transition portion, and a portion of the second equal-diameter portion, and an elastic modulus of the coil 560 is less than or equal to an elastic modulus of the distal guide wire 510. So can strengthen the intensity that the conveyor's of implant cladding has the part of coil 560 when not influencing the pliability, through increasing the external diameter, strengthen the ability of buckling of the near-end seal wire of part, and the power conduction is better, promotes the propelling movement performance, does not have the influence to the pliability almost simultaneously, and is difficult for avoiding conveyor to buckle.

Specifically, as shown in fig. 5, the coil 560 is wrapped around the outer circumference of the first equal-diameter section 521 near the distal end of the first equal-diameter section 521, around the outer circumference of the variable-diameter section 522, and around the outer circumference of the second equal-diameter section 523 near the proximal end of the second equal-diameter section 523.

The distal end of the coil 560 is fixedly connected to the first fixing member 551. In other embodiments, the distal end of the coil 560 is separate from the first mount 551.

The outer diameter of the coil 560 varies with the diameter of the portion it surrounds. Specifically, the outer diameter of the coil 560 may vary from 0.11 to 1.97mm, and the wire diameter of the coil 560 may be from 0.001 to 0.0025 inch.

The length of the coil 560 may be 200-800 mm.

In other embodiments, the coil 560 may be replaced by a polymer tube, or the coil 560 may be wrapped with a polymer tube as a sheath wrapped over the distal portion of the delivery device of the implant, and the sheath has a modulus of elasticity less than or equal to that of the distal guidewire 510 to improve the bending resistance of the distal portion of the delivery device of the implant without affecting the flexibility of the distal portion. Wherein, the material of the polymer tube is preferably one or a combination of more of polytetrafluoroethylene, polyethylene terephthalate or polyolefin; the material of the coil 560 is preferably one or more of nickel-titanium alloy, platinum-iridium alloy, platinum-tungsten alloy, stainless steel, etc.

EXAMPLE six

The present embodiment provides a delivery device for an implant, which is different from the delivery device for an implant in the first embodiment mainly in that, in the present embodiment, the structure of the junction between the proximal guide wire and the distal guide wire is different.

Referring to fig. 7, fig. 7 is a schematic structural diagram of a delivery device of an implant according to a sixth embodiment of the present invention, the delivery device of the implant includes a distal guide wire 610 and a proximal guide wire 620, a proximal end of the distal guide wire 610 is fixedly connected to a distal end of the proximal guide wire 620, and an elastic modulus of the proximal guide wire 620 is greater than an elastic modulus of the distal guide wire 610. Because the elastic modulus of the proximal guide wire 620 is greater than that of the distal guide wire 610, the pushing performance of the proximal guide wire 620 is good, and the flexibility of the distal guide wire 610 is good, so that the implant delivery device has both pushing performance and flexibility.

The proximal guide wire 620 is made of stainless steel, and the distal guide wire 610 is made of nitinol, so that better proximal pushability and better distal flexibility can be achieved through material changes. According to the embodiment, the rigidity of the implant conveying device is changed section by section through the change of the outer diameters of the near-end guide wire and the far-end guide wire and the arrangement of the connecting positions of the near-end guide wire and the far-end guide wire, and meanwhile, the process is simple and the connection reliability is high.

The proximal guidewire 620 may be 1400-1900mm in length and the distal guidewire 610 may be 300-700mm in length. The ratio of the lengths of the proximal guidewire 620 and the distal guidewire 610 can be 2:1 to 19: 3.

The proximal guide wire 620 and the distal guide wire 610 are threaded.

Specifically, the proximal guide wire 620 has a screw hole 622, the screw hole 622 is provided on the distal end surface of the proximal guide wire 620 along the axis of the proximal guide wire 620, the outer peripheral surface of the proximal end of the distal guide wire 610 is provided with threads matching with the screw hole 622, and the distal guide wire 610 and the proximal guide wire 620 can be fixedly connected through the screw hole 622 and the threads.

The diameter of the screw hole 622 may be 0.1-0.3mm, and the length of the screw hole 622 may be 10-200 mm.

The proximal guide wire 620 and the distal guide wire 610 may be further welded on the basis of the threaded connection. Such as by welding at the interface of the threaded bore 622 and the threads. Wherein, the welding mode includes but not limited to: laser welding, resistance welding, and pulse welding.

The delivery device of the implant includes a first major diameter portion, a transition portion, and a second major diameter portion. The first equal-diameter part, the transition part and the second equal-diameter part are sequentially connected from the near end to the far end, the outer diameter of the first equal-diameter part is larger than that of the second equal-diameter part, the outer diameter of the near end of the transition part is equal to that of the first equal-diameter part, the outer diameter of the far end of the transition part is equal to that of the second equal-diameter part, and the outer diameter of the transition part is gradually reduced from the near end to the far end. In this embodiment, the transition portion is disposed on the distal guidewire. The proximal guide wire 620 is cylindrical and has a diameter of 0.2-0.7 mm.

The distal guide wire 610 includes a first segment 611, a second segment 612, and a third segment 613, and the first segment 611, the second segment 612, and the third segment 613 are sequentially connected from a proximal end to a distal end. Wherein the proximal end of the first segment 611 is connected to the proximal guidewire 620. The proximal end face of the distal guide wire 610 and the proximal end face of the first segment 611 are the same end face.

The first segment 611 is cylindrical and has a proximal end connected to a proximal guidewire 620. The first section 611 is an equal diameter section, and the diameter of the first section 611 may be 0.1-0.3mm, and the length thereof may be 10-400 mm.

The third segment 613 is also cylindrical. The third segment 613 is a constant diameter segment having a diameter smaller than that of the first segment 611, for example: is 0.06-0.22mm, and its length can be 20-80 mm.

The second segment 612 is located between the first segment 611 and the third segment 613, and has a proximal end connected to the first segment 611 and a distal end connected to the third segment 613. The second section 612 is in a circular truncated cone shape, the diameter of the second section 612 gradually decreases from the proximal end to the distal end, the diameter of the proximal end is equal to the diameter of the first section 611, and the diameter of the distal end is equal to the diameter of the third section 613. Wherein the length of the second section 612 can be 150-500 mm.

In this embodiment, part of the second section 612 is the transition portion.

Preferably, the distal outer diameter of the proximal guide wire 620 is slightly larger than the diameter of the first segment 611 of the distal guide wire 610, so that when the distal guide wire 610 is inserted into the screw hole 622 of the proximal guide wire 620, the outer surface of the delivery device of the implant can be smoothly transited, the outer diameter of the delivery device of the implant does not suddenly become smaller, and thus the whole delivery device of the implant can be made to be similar to a streamline shape, and the delivery device with the implant can be more smoothly advanced in the blood vessel. In other embodiments, the diameter of the proximal guide wire can also be gradually reduced from the distal end to the proximal end, the proximal guide wire can also be formed by splicing multiple materials, but from the comprehensive consideration of process difficulty, efficiency, cost and the like, only one part of the guide wire is required to be of a reducing structure and is connected with the other part of the guide wire which is not of the reducing structure but has a different elastic modulus, and the requirements on the pushing performance and the flexibility can be met.

The delivery device for the implant further comprises a head 630, a first fastener 641 and a second fastener 642. The size, structure, function and connection between the head 630, the first fixing element 641 and the second fixing element 642 and the proximal guide wire 620 and the distal guide wire 610 are similar to those of the implant delivery device in the first embodiment, and thus the description thereof is omitted.

The delivery device of the implant further comprises a sheath, the sheath comprises a coil 650, and the coil 650 is coated on the outer peripheral surfaces of the proximal guide wire 620 and the distal guide wire 610. Specifically, the coil 650 may be wrapped around a portion of the first constant diameter portion, the transition portion, and a portion of the second constant diameter portion. So can strengthen the conveyor cladding of conveyor implant has the intensity of the part of coil 650, through increasing the external diameter, strengthens the ability of buckling resistance of the near-end seal wire of part distal end seal wire and part, and power conduction is better, promotes the propelling movement performance, does not have the influence to the pliability almost simultaneously, and is difficult for avoiding conveyor to buckle.

Specifically, as shown in fig. 7, the coil 650 is coated on the outer peripheral surface of the portion of the proximal guide wire 620 near the distal end, the outer peripheral surface of the portion of the first segment 611 not inserted into the screw hole 622, the outer peripheral surface of the second segment 612, and the outer peripheral surface of the portion of the third segment 613 near the proximal end.

The distal end of the coil 650 is fixedly connected to the first fixing member 641. In other embodiments, the distal end of the coil 650 is separated from the first fixing member 641.

The outer diameter of the coil 650 varies with the diameter of the portion it surrounds. Specifically, the outer diameter of the coil 650 may vary in the range of 0.11 to 1.97mm, and the wire diameter of the coil 650 may be 0.001 to 0.0025 inch.

The length of the coil 650 may be 200-800 mm.

In other embodiments of the present invention, the sheath may also be a polymer tube, or the sheath may include a coil 650 and at least one polymer tube. For example, the sheath comprises a coil 650 and a polymer tube, the polymer tube being sheathed outside the coil 650, the coil 650 being helically wound at least on the transition portion and the proximal portion of the second reduced diameter portion of the delivery device for the implant; for another example, the sheath may include a coil 650 and two polymer tubes, one of which is sleeved over a distal portion of the first constant diameter portion, a transition portion, and a proximal portion of the second constant diameter portion of the delivery device of the implant, the coil 650 being helically wound around the exterior of the polymer tube, and the other of which is sleeved over the exterior of the coil 650. Wherein, the material of the polymer tube is preferably one or a combination of more of polytetrafluoroethylene, polyethylene terephthalate or polyolefin; the material of the coil is preferably one or more of nickel-titanium alloy, platinum-iridium alloy, platinum-tungsten alloy, stainless steel or the like. By wrapping the sheath over the distal portion of the delivery device of the implant, and having a modulus of elasticity less than or equal to the modulus of elasticity of the distal guidewire 610, the bending resistance of the distal portion of the delivery device of the implant is increased without affecting its flexibility.

EXAMPLE seven

The present embodiments provide a delivery device for an implant. The essential differences between the delivery device of the implant in this embodiment and the other embodiments are: the transition is disposed on the proximal guidewire and the junction of the proximal guidewire and the distal guidewire is disposed on the distal end of the transition.

In this embodiment, the structure of the joint between the proximal guide wire and the distal guide wire may refer to all designs in other embodiments, including the structure (slope structure) of the joint between the proximal guide wire and the distal guide wire in the first embodiment, the structure (clamping structure) of the joint between the proximal guide wire and the distal guide wire in the second embodiment, and the structure (connecting structure) of the connecting member between the proximal guide wire and the distal guide wire in the fourth embodiment.

The "proximal" and "distal" in the above embodiments are relative orientations, relative positions, directions of elements or actions with respect to each other from the perspective of a physician using the medical device, although "proximal" and "distal" are not intended to be limiting, but "proximal" generally refers to the end of the medical device that is closer to the physician during normal operation, and "distal" generally refers to the end that is first introduced into the patient.

As used in this specification and the appended claims, the singular forms "a", "an", and "the" include plural referents unless the content clearly dictates otherwise. As used in this specification and the appended claims, the term "or" is generally employed in its sense including "and/or" unless the content clearly dictates otherwise. For ease of description, the expressions "first constant diameter portion", "second constant diameter portion", and "uniform outer diameter" are used in the present specification and the appended claims, and it will be understood by those skilled in the art that the expressions do not indicate absolute constant diameters, and for example, there may be slight diameter variations due to surface grooves, protrusions, coatings, and the like.

The above description is only for the preferred embodiment of the present invention and is not intended to limit the scope of the present invention, and any modification and modification made by those skilled in the art according to the above disclosure are all within the scope of the claims.

Claims

1. The implant conveying device is characterized by comprising a distal guide wire and a proximal guide wire, wherein the proximal end of the distal guide wire is fixedly connected with the distal end of the proximal guide wire, and the elastic modulus of the proximal guide wire is larger than that of the distal guide wire.

2. The implant delivery device of claim 1, comprising a first constant-diameter portion, a transition portion and a second constant-diameter portion which are sequentially connected from a proximal end to a distal end, wherein the first constant-diameter portion and the second constant-diameter portion have a uniform outer diameter, the first constant-diameter portion has an outer diameter larger than that of the second constant-diameter portion, the transition portion has a proximal end having an outer diameter equal to that of the first constant-diameter portion, the transition portion has a distal end having an outer diameter equal to that of the second constant-diameter portion, and the transition portion has an outer diameter gradually decreasing from the proximal end to the distal end.

3. The implant delivery apparatus of claim 2, wherein the transition portion is disposed on the distal guidewire and the proximal guidewire and the distal guidewire have a length ratio of 2:1 to 6.5: 1; or the transition part is arranged on the proximal guide wire, and the length ratio of the proximal guide wire to the distal guide wire is 13:1 to 42: 1; or the transition part is arranged at the connection part of the proximal guide wire and the distal guide wire, and the length ratio of the proximal guide wire to the distal guide wire is 6.5:1 to 13: 1.

4. The implant delivery apparatus of claim 1, wherein the proximal guidewire is made of stainless steel and the distal guidewire is made of nitinol.

5. The implant delivery apparatus of claim 1, wherein the proximal guidewire and the distal guidewire are welded.

6. The implant delivery device according to claim 5, wherein the distal end surface of the proximal guide wire is tapered, the proximal end surface of the distal guide wire is tapered, and the distal end surface of the proximal guide wire and the proximal end surface of the distal guide wire match each other in shape, the implant delivery device further comprising at least two weld points disposed between the distal end surface of the proximal guide wire and the proximal end surface of the distal guide wire.

7. The implant delivery device of claim 6, wherein the angle between the proximal end face of the distal guide wire and the axis of the distal guide wire is a first angle, the angle between the distal end face of the proximal guide wire and the axis of the proximal guide wire is a second angle, the first angle is equal to the second angle, and the first angle and the second angle are in the range of 45 ° -90 °.

8. The implant delivery device according to claim 5, wherein the proximal guide wire comprises a proximal main body and a proximal connecting portion, the distal end of the proximal main body is fixedly connected with the proximal end of the proximal connecting portion, the distal guide wire comprises a distal main body and a distal connecting portion, the distal end of the distal connecting portion is fixedly connected with the proximal end of the distal main body, the proximal connecting portion and the distal connecting portion are mutually clamped, and the proximal connecting portion and the distal connecting portion are mutually welded.

9. The implant delivery device of claim 8, wherein the proximal coupling portion comprises a first recess and a first protrusion, and the distal coupling portion comprises a second recess and a second protrusion, wherein the second protrusion fits into the first recess and the first protrusion fits into the second recess when the proximal coupling portion and the distal coupling portion are engaged.

10. The implant delivery apparatus according to claim 1, wherein a fixing hole is formed in a distal end surface of the proximal guide wire, the fixing hole extends in an axial direction of the proximal guide wire, and a proximal end of the distal guide wire is embedded in the fixing hole.

11. The implant delivery apparatus according to claim 1, further comprising a connector, wherein a proximal end of the connector is fixedly connected to the proximal guide wire and a distal end of the connector is fixedly connected to the distal guide wire.

12. The implant delivery apparatus according to claim 11, further comprising at least one fastener disposed over the distal guidewire for securing an axial position of the implant, the fastener being integral with the connector.

13. The implant delivery apparatus of claim 1, wherein the proximal guidewire and the distal guidewire are threaded.

14. The implant delivery device of claim 2, further comprising a sheath that covers an outer peripheral surface of the transition portion and/or the second major diameter portion, wherein the sheath has a modulus of elasticity that is less than or equal to the modulus of elasticity of the distal guidewire.

15. The implant delivery apparatus of claim 14, wherein the sheath comprises a polymeric tube and/or a helically wound coil.

16. A luminal implant system comprising a luminal implant, a catheter and a delivery device of the implant of any of claims 1 to 15, the delivery device of the implant being movably disposed through the catheter, the luminal implant being detachably connected to the distal end of the delivery device of the implant.