CN211069726U

CN211069726U - Minocycline processing is with buffer solution blending tank

Info

Publication number: CN211069726U
Application number: CN201921648332.5U
Authority: CN
Inventors: 王萍; 刘劲松; 王世表; 邱志才
Original assignee: Hubei Kelevi Biopharmaceutical Technology Co ltd
Current assignee: Hubei Kelaiwei Biopharmaceutical Co ltd
Priority date: 2019-09-29
Filing date: 2019-09-29
Publication date: 2020-07-24
Anticipated expiration: 2029-09-29

Abstract

The utility model discloses a minocycline processing buffer solution blending tank, which comprises a tank shell, a solution feeding port, an upper cover base, an upper cover, a stirring motor, a shaft outer sleeve rod, an outer sleeve rod connecting base, a stirring shaft, stirring blades and a spraying device, wherein the top of the tank shell is provided with the upper cover base, the outer side of the stirring shaft in the tank shell is provided with the shaft outer sleeve rod, the top of the shaft outer sleeve rod is provided with the outer sleeve rod connecting base, the stirring blades are arranged at the bottom of the stirring shaft, the spraying device is arranged at the bottom of the tank shell, buffer solution preparation which is being prepared in the tank is sucked in from an absorption head through a liquid suction pump and is conveyed into an annular sleeve through an absorption elbow, the liquid suction pump and a conveying pipe, the spray head is sprayed through an inner pipeline in the annular sleeve, gaseous molecules at the air end in the tank shell are volatilized and stored, and fall into the buffer solution preparation at the, the problem that the concentration of the buffer solution is reduced due to volatilization of the buffer solution which is not used immediately is avoided.

Description

Minocycline processing is with buffer solution blending tank

Technical Field

The utility model relates to a minocycline technical field specifically is a minocycline processing is with buffer solution allotment jar.

Background

Minocycline, also known as minocycline or mecycline, is a broad-spectrum antibacterial tetracycline antibiotic, can be combined with tRNA to achieve the antibacterial effect, has a wider antibacterial spectrum and antibacterial activity than similar drugs, is close to tetracycline, has strong effects on gram-positive bacteria including tetracycline-resistant staphylococcus aureus, streptococcus and Neisseria gonorrhoeae in gram-negative bacteria, has weak effects on gram-negative bacteria generally, has good inhibitory effects on chlamydia trachomatis and ureolyticum, is prepared by azo reduction and chlorine protection diazo methods, needs a large amount of buffer solution during preparation to protect the pH value of a preparation and avoid the preparation failure caused by partial acid or partial alkali, in the buffer solution preparation technology in the prior art, the buffer solutions of the two processes are prepared, the buffer solution is prepared by respectively using ammonia water and tetrahydrofuran, and the ammonia water and the tetrahydrofuran both have the characteristic of easy volatilization, so that the components in the buffer solution are reduced and the concentration is reduced if the buffer solution is not used immediately after the preparation is finished, so that the effect of the buffer solution is reduced approximately, and the effect of fixing the pH value cannot be achieved.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a minocycline processing is with buffer solution allotment jar, set up atomizer in the jar shell of allotment jar, in the in-process of preparation, prepare buffer solution preparation and inhale from the absorption head in with jar through the drawing liquid pump, and via absorbing the return bend, drawing liquid pump and conveyer pipe, carry to the ring casing in, it sprays to reach the atomising head through the inside pipeline in the ring casing, because the buffer solution preparation that sprays still is liquid form, can be with volatilizing and preserve in the tank casing in the gaseous state molecular tape of air end, and fall into again in the buffer solution preparation of downside, in order to reach the function of long-time saving, avoid the buffer solution that does not use immediately, because volatilize the problem that causes the buffer solution concentration to reduce, can solve the problem among the prior art.

In order to achieve the above object, the utility model provides a following technical scheme:

the utility model provides a minocycline processing is with buffer solution allotment jar, includes jar shell, solution inlet, upper cover base, upper cover, agitator motor, axle overcoat loop bar, overcoat pole connection base, (mixing) shaft, stirring vane and atomizer, the upper right side of jar shell is equipped with solution inlet, the top of jar shell is equipped with the upper cover base, the upper cover is installed to the upside of upper cover base, the inboard installation agitator motor of upper cover, agitator motor's downside is connected the (mixing) shaft, the (mixing) shaft outside in the jar shell is equipped with an overcoat loop bar, the top of axle overcoat loop bar is equipped with overcoat pole connection base, the bottom installation stirring vane of (mixing) shaft, the bottom of jar shell is equipped with atomizer.

The spraying device comprises a pump shell, a shell base, a liquid pump, an absorption elbow, an absorption head, a conveying pipe, an annular sleeve, a spraying head, an annular connecting plate, a fixing bolt, a sealing plate, a sealing bolt group and a sealing ring, the bottom of the pump shell is provided with a shell base, the pump shell is internally provided with a liquid pump, the right side of the liquid pump is provided with an absorption elbow, the tail end of the absorption elbow is provided with an absorption head, the left upper side of the liquid pump is provided with a delivery pipe, the tail end of the delivery pipe is connected with the annular sleeve, the outer side of the annular sleeve is provided with a spray head, the upper side of the annular sleeve is provided with an annular connecting plate, a plurality of fixing bolts are arranged on the annular connecting plate, a sealing plate is arranged at the inner side of the joint of the absorption elbow pipe, the conveying pipe and the pump shell, the sealing plate is provided with a sealing bolt group, and the pump shell, the absorption elbow and the conveying pipe are internally provided with sealing rings.

Preferably, the annular sleeve is fixed on the outer sleeve rod of the shaft through an annular connecting plate at the upper side and a fixing bolt.

Preferably, the shaft outer sleeve rod is fixedly arranged on the inner wall of the top end of the tank shell through an outer sleeve rod connecting base.

Preferably, the absorbent head is of a flat mouth type.

Preferably, the delivery pipe is connected to the spray head by an internal conduit connecting the annular sleeve.

Compared with the prior art, the beneficial effects of the utility model are as follows:

the utility model discloses minocycline processing is with buffer solution allotment jar, set up atomizer in the jar shell of allotment jar, at the in-process of preparation, prepare buffer solution preparation and inhale from the absorption head in with jar through the drawing liquid pump, and via absorbing the return bend, drawing liquid pump and conveyer pipe, carry to the ring casing in, reach the atomising head through the inside pipeline in the ring casing and spray, because the buffer solution preparation that sprays still is liquid form, can be with volatilizing and preserve in the gaseous state molecular tape of jar shell internal air end, and fall into the buffer solution preparation of downside again in, in order to reach the long-time function of preserving, the utility model discloses it is complete reasonable in structure, effectively avoided the buffer solution that does not use immediately, owing to volatilize the problem that causes buffer solution concentration to reduce.

Drawings

FIG. 1 is a schematic sectional view of the present invention;

FIG. 2 is a schematic cross-sectional view of the pump housing of the present invention;

fig. 3 is a schematic structural diagram of the annular sleeve of the present invention;

fig. 4 is an enlarged view of a point a of the present invention.

In the figure: 1. a canister housing; 2. a solution inlet; 3. an upper cover base; 4. an upper cover; 5. a stirring motor; 6. a shaft outer sleeve rod; 7. the outer loop bar is connected with the base; 8. a stirring shaft; 9. a stirring blade; 10. a spraying device; 101. a pump housing; 102. a housing base; 103. a liquid pump; 104. an absorption bend; 105. an absorption head; 106. a delivery pipe; 107. an annular sleeve; 108. a spray head; 109. an annular connecting plate; 1010. fixing the bolt; 1011. a sealing plate; 1012. a sealing bolt group; 1013. and (5) sealing rings.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Referring to fig. 1, a minocycline processing buffer solution preparation tank comprises a tank shell 1, a solution inlet 2, an upper cover base 3, an upper cover 4 and a stirring motor 5, axle overcoat post 6, overcoat post connection base 7, (mixing) shaft 8, stirring vane 9 and atomizer 10, jar shell 1's upper right side is equipped with solution inlet 2, jar shell 1's top is equipped with upper cover base 3, upper cover 4 is installed to upper cover base 3's upside, upper cover 4's inboard installation agitator motor 5, agitator motor 5's downside is connected (mixing) shaft 8, the (mixing) shaft 8 outside in jar shell 1 is equipped with axle overcoat post 6, axle overcoat post 6 is through overcoat post connection base 7 fixed mounting on jar shell 1's top inner wall, the top of axle overcoat post 6 is equipped with overcoat post connection base 7, stirring vane 9 is installed to the bottom of (mixing) shaft 8, jar shell 1's bottom is equipped with atomizer 10.

Referring to fig. 2-4, the spraying apparatus 10 includes a pump housing 101, a housing base 102, a liquid pump 103, an absorption elbow 104, an absorption head 105, a delivery pipe 106, a ring-shaped casing 107, a spraying head 108, a ring-shaped connecting plate 109, a fixing bolt 1010, a sealing plate 1011, a sealing bolt set 1012 and a sealing ring 1013, the housing base 102 is disposed at the bottom of the pump housing 101, the liquid pump 103 is mounted inside the pump housing 101, the absorption elbow 104 is mounted at the right side of the liquid pump 103, the absorption head 105 is mounted at the end of the absorption elbow 104, the absorption head 105 is flat, the delivery pipe 106 is mounted at the upper left side of the liquid pump 103, the end of the delivery pipe 106 is connected to the ring-shaped casing 107, the ring-shaped casing 107 is fixed to the shaft jacket 6 by the ring-shaped connecting plate 109 and the fixing bolt 1010 at the upper side, the spraying head 108 is disposed at the outer side of the ring-, the upper side of the annular sleeve 107 is provided with an annular connecting plate 109, the annular connecting plate 109 is provided with a plurality of fixing bolts 1010, the inner side of the joint of the absorption elbow 104 and the delivery pipe 106 with the pump shell 101 is provided with a sealing plate 1011, the sealing plate 1011 is provided with a sealing bolt group 1012, and the pump shell 101, the absorption elbow 104 and the delivery pipe 106 are internally provided with a sealing ring 1013.

The utility model discloses difference with prior art: in the buffer solution preparation technology of the prior art, the buffer solutions of the two processes are respectively prepared by using ammonia water and tetrahydrofuran, and the ammonia water and the tetrahydrofuran both have volatile characteristics, if the buffer solutions are not used immediately after the preparation is finished, the components in the buffer solutions are reduced, the concentration is reduced, and the effect of the buffer solutions is reduced approximately, and the effect of the buffer solutions cannot be fixed, the buffer solution preparation tank for minocycline processing of the utility model is characterized in that a spraying device 10 is arranged in a tank shell 1 of the preparation tank, in the preparation process, the buffer solution preparation being prepared in the tank is sucked from an absorption head 105 through a liquid pump 103, is conveyed to an annular sleeve 107 through an absorption elbow 104, a liquid pump 103 and a conveying pipe 106, and reaches a spraying head 108 through an internal pipeline in the annular sleeve 107 for spraying, and the sprayed buffer solution preparation is in a liquid state, and can be volatilized and stored under a gaseous molecular band at an air end in the tank shell 1, and falls into the buffer solution preparation on the lower side again to achieve the function of long-time preservation, and the problem that the concentration of the buffer solution is reduced due to volatilization of the buffer solution which is not used immediately is solved.

In summary, the following steps: the utility model discloses minocycline processing is with buffer solution allotment jar, set up atomizer 10 in the jar shell 1 of allotment jar, in the in-process of preparation, it inhales from absorption head 105 to prepare buffer solution preparation in with jar through drawing liquid pump 103, and via absorption return bend 104, drawing liquid pump 103 and conveyer pipe 106, carry to among the ring casing 107, reach atomising head 108 through the inside pipeline in the ring casing 107 and spray, because the buffer solution preparation that sprays still is liquid form, can volatilize and preserve in jar shell 1 in the gaseous state molecular tape of air end, and fall into again in the buffer solution preparation of downside, in order to reach the long-time function of preserving, the utility model discloses it is complete reasonable in structure, effectively avoided the buffer solution that does not use immediately, owing to volatilize the problem that causes buffer solution concentration to reduce.

It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a minocycline processing is with buffer solution allotment jar, includes jar shell (1), solution inlet (2), upper cover base (3), upper cover (4), agitator motor (5), axle loop bar (6), loop bar connection base (7), (mixing) shaft (8), stirring vane (9) and atomizer (10), its characterized in that: a solution feeding port (2) is formed in the upper right side of the tank shell (1), an upper cover base (3) is arranged at the top of the tank shell (1), an upper cover (4) is installed on the upper side of the upper cover base (3), a stirring motor (5) is installed on the inner side of the upper cover (4), a stirring shaft (8) is connected to the lower side of the stirring motor (5), a shaft outer sleeve rod (6) is arranged on the outer side of the stirring shaft (8) in the tank shell (1), an outer sleeve rod connecting base (7) is arranged at the top of the shaft outer sleeve rod (6), stirring blades (9) are installed at the bottom of the stirring shaft (8), and a spraying device (10) is arranged at the bottom of the tank shell (1);

the spraying device (10) comprises a pump shell (101), a shell base (102), a liquid pump (103), an absorption elbow (104), an absorption head (105), a delivery pipe (106), an annular sleeve (107), a spraying head (108), an annular connecting plate (109), a fixing bolt (1010), a sealing plate (1011), a sealing bolt group (1012) and a sealing ring (1013), wherein the shell base (102) is arranged at the bottom of the pump shell (101), the liquid pump (103) is arranged inside the pump shell (101), the absorption elbow (104) is arranged on the right side of the liquid pump (103), the absorption head (105) is arranged at the tail end of the absorption elbow (104), the delivery pipe (106) is arranged on the upper left side of the liquid pump (103), the tail end of the delivery pipe (106) is connected onto the annular sleeve (107), the spraying head (108) is arranged on the outer side of the annular sleeve (107), the upside of ring sleeve pipe (107) is equipped with annular connecting plate (109), install a plurality of fixing bolt (1010) on annular connecting plate (109), it seals board (1011) to absorb elbow pipe (104) and conveyer pipe (106) and pump housing (101) junction inboard, seal board (1011) and go up the installation and seal bolt group (1012), pump housing (101) and the inside of absorbing elbow pipe (104) and conveyer pipe (106) are equipped with sealing washer (1013).

2. The buffer dispensing tank for minocycline processing of claim 1, wherein: the annular sleeve (107) is fixed on the outer sleeve rod (6) of the shaft through an annular connecting plate (109) on the upper side and a fixing bolt (1010).

3. The buffer dispensing tank for minocycline processing of claim 1, wherein: the outer loop bar (6) of the shaft is fixedly arranged on the inner wall of the top end of the tank shell (1) through an outer loop bar connecting base (7).

4. The buffer dispensing tank for minocycline processing of claim 1, wherein: the absorption head (105) is flat.

5. The buffer dispensing tank for minocycline processing of claim 1, wherein: the delivery pipe (106) is connected to the spray head (108) by means of an internal conduit connecting the annular sleeve (107).