CN2109570U - Automatic analyser for urine - Google Patents
Automatic analyser for urine Download PDFInfo
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- CN2109570U CN2109570U CN 91231857 CN91231857U CN2109570U CN 2109570 U CN2109570 U CN 2109570U CN 91231857 CN91231857 CN 91231857 CN 91231857 U CN91231857 U CN 91231857U CN 2109570 U CN2109570 U CN 2109570U
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- automatic analyzer
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- 210000002700 urine Anatomy 0.000 title claims abstract description 45
- 239000000523 sample Substances 0.000 claims abstract description 75
- 238000012360 testing method Methods 0.000 claims abstract description 37
- 230000003287 optical effect Effects 0.000 claims abstract description 15
- 238000000034 method Methods 0.000 claims abstract description 8
- 230000008569 process Effects 0.000 claims abstract description 6
- 238000001514 detection method Methods 0.000 claims description 33
- 239000000835 fiber Substances 0.000 claims description 32
- 230000011664 signaling Effects 0.000 claims description 14
- 239000013078 crystal Substances 0.000 claims description 6
- 239000012141 concentrate Substances 0.000 claims description 5
- 239000002184 metal Substances 0.000 claims description 3
- 229910052751 metal Inorganic materials 0.000 claims description 3
- 206010070834 Sensitisation Diseases 0.000 claims description 2
- 238000009342 intercropping Methods 0.000 claims description 2
- 239000007769 metal material Substances 0.000 claims description 2
- 230000008313 sensitization Effects 0.000 claims description 2
- 238000003860 storage Methods 0.000 claims description 2
- OBHRVMZSZIDDEK-UHFFFAOYSA-N urobilinogen Chemical compound CCC1=C(C)C(=O)NC1CC1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(CC3C(=C(CC)C(=O)N3)C)N2)CCC(O)=O)N1 OBHRVMZSZIDDEK-UHFFFAOYSA-N 0.000 abstract description 10
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 abstract description 7
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 abstract description 7
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract description 5
- 239000008280 blood Substances 0.000 abstract description 5
- 210000004369 blood Anatomy 0.000 abstract description 5
- 230000005540 biological transmission Effects 0.000 abstract description 4
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 102000004169 proteins and genes Human genes 0.000 abstract description 4
- 108090000623 proteins and genes Proteins 0.000 abstract description 4
- 230000007797 corrosion Effects 0.000 abstract description 2
- 238000005260 corrosion Methods 0.000 abstract description 2
- 238000005516 engineering process Methods 0.000 abstract description 2
- 150000002576 ketones Chemical class 0.000 abstract description 2
- 239000008121 dextrose Substances 0.000 abstract 1
- 239000013307 optical fiber Substances 0.000 abstract 1
- 239000003990 capacitor Substances 0.000 description 20
- 238000009535 clinical urine test Methods 0.000 description 12
- 229910052710 silicon Inorganic materials 0.000 description 10
- 239000010703 silicon Substances 0.000 description 10
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 6
- 238000010586 diagram Methods 0.000 description 6
- 239000003985 ceramic capacitor Substances 0.000 description 4
- 239000011248 coating agent Substances 0.000 description 4
- 238000000576 coating method Methods 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- 239000011159 matrix material Substances 0.000 description 4
- 230000002093 peripheral effect Effects 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 230000000087 stabilizing effect Effects 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 3
- 238000012764 semi-quantitative analysis Methods 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000004737 colorimetric analysis Methods 0.000 description 2
- 230000000295 complement effect Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000007639 printing Methods 0.000 description 2
- 238000005070 sampling Methods 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 238000007705 chemical test Methods 0.000 description 1
- 238000013098 chemical test method Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
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- 238000007599 discharging Methods 0.000 description 1
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- 239000012153 distilled water Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 229910052736 halogen Inorganic materials 0.000 description 1
- 150000002367 halogens Chemical class 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000005055 memory storage Effects 0.000 description 1
- GQPLMRYTRLFLPF-UHFFFAOYSA-N nitrous oxide Inorganic materials [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 238000004451 qualitative analysis Methods 0.000 description 1
- 230000011218 segmentation Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 1
- 229910052721 tungsten Inorganic materials 0.000 description 1
- 239000010937 tungsten Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
The utility model relates to an automatic urine analyzer which is composed of a sample conveying device and an optical fiber sensor controlled by a microcomputer. Samples to be detected pass through fixed optical probes one by one. The utility model is suitable for dry type chemistry test paper and can detect the nitrite, pH, dextrose, protein, occult blood, ketone bodies, bilirubin and urobilinogen of urine. Compared with the existing foreign products, the utility model has the advantages of advanced technology, simple manufacture process, wide transmission band, less consumption, no interference of circumferential magnetic fields, stable operation, low cost, strong corrosion resistance performance and long service life.
Description
The present invention relates to a kind of hospital clinical testing instruments, particularly a kind of micro-processor controlled automatic analyzer for urine.
Urine test is the conventional project in modern medical engineering and the clinical treatment, is one of " three big routine inspections ".
It is not only the diagnosis disease in the urological system, and the important means of observe the curative effect, also is other disease, as the laboratory examination method commonly used of internal system disorder disease.
For a long time, many processes of this check as sampling, filtration, centrifugal, chemical analysis and colorimetric etc., all are to adopt manually-operated, and formality is numerous and diverse, and work efficiency is low.
At present, the prior art qualitative, semi-quantitative analysis to above-mentioned test item is:
At home, be artificial color comparison of naked eye method, exist the collimation error of proofer's experience and ambient light influence, poor accuracy.
Abroad, Japanese and German, develop " computer automatic analyzer for urine ", but its critical component---optical sensor, general integrating sphere type luminosity sensor or the LED array sensor of adopting, what their adopted is older luminosity measurement method, described as day disclosure special permission " flat 2-27262 " and " flat 2-161354 ", exist manufacture and design requirement height, complex process, rapid wear, easily wear out, environmental requirement is high and deficiency such as high price.
Purpose of the present invention, to overcome the deficiencies in the prior art exactly, in the selection of optical sensor, break through existing pattern, make a kind of technical more advanced, reliability and stability are higher and inexpensive, extensively popularization and application in immensely, the automatic analyzer for urine of intermediate hospitals such as city, county.
The objective of the invention is to realize by following measure:
Make a kind of modified automatic analyzer for urine, it is characterized in that:
By micro-processor controlled optical sensor and sample conveyor is that main body constitutes,
1. machine shell is divided into cover and base two large divisions,
1. go up the outside of cover and concentrate the parts that are provided with whole outside contact, comprising: printer (5), all kinds of pilot lamp (10), all kinds of switch (11), sample input port (9), cartridge fuse (8), useless test paper outlet (52) etc.,
2. on the base of metal material, concentrate and settle movement, comprising: host circuit board, power supply, Control System of Microcomputer, fiber optic sensor parts and the sample conveyor etc. that constitute by integrated circuit and discrete component,
2. Control System of Microcomputer is made up of MCS-51 series monolithic, external storage, A/D converter, data latches, crystal oscillator body, integrated circuit and discrete component,
3. optical sensor adopts fiber optic sensor (1),
4. sample conveyor (2) is the travelling belt (20) of circular flow, carries sample to be detected (22), one by one by fixing optic probe (14).
Above-mentioned automatic analyzer for urine, the fiber optic sensor that it is characterized in that this instrument is that sequence unit instrument light (12), fibre-optic bundle (13), monochromator (15), photoelectric commutator (16) and signal amplifier (17) in metal shell (18).
In the fiber optic sensor:
1. power supply (26) is powered to instrument light (12),
2. the emission light of instrument light (12), through fibre-optic bundle (13), directive sample to be detected (22), probe (14) captures, and through the reflected light after monochromator (15) processing, become electric signal through photoelectric commutator (16), the output terminal through (16) links to each other with the input end of signal amplifier (17)
3. the simulating signal that produces of amplifier, the output terminal through (17) is by the CPU of A/D converter (3) input Control System of Microcomputer.
4. the fibre-optic bundle in the fiber optic sensor (13) is divided into light source beam and reflected light and accepts two kinds of bundles, and its structure is: with placing in the wire chamber, is center, concentric circles of composition by n bundle light transmitting fiber with the light source beam.
The light source from instrument light is accepted over against instrument light (12) in the upper end of light source beam, and sample to be detected (22) is scanned by probe (14) in the lower end,
Reflected light is accepted an end of bundle, captures the sample reflected light by probe (14), and the other end is divided into n-1 optical channel, send monochromator (15) with reflected light.
In the fibre-optic bundle (13), the diameter ratio between the light source beam of combination and reflected light are accepted to restraint with one heart is 0.1～0.5:1～10.
Above-mentioned automatic analyzer for urine is characterized in that the sample conveyor of this instrument is, is made up of servomotor (25), engaged wheel (19), travelling belt (20), bracing frame (23), rinse bath (21) and sample detection signalling means (24).Wherein:
1. servomotor (25) drives driving-belt (20), in engaged wheel (19) intercropping circular flow,
2. passage is traversed on the top of bracing frame (23), is supporting travelling belt (20), and its spacing be able to make travelling belt (20) and test paper pass through,
3. passage is traversed at the middle part of rinse bath (21), and travelling belt passes through therebetween,
4. the position of sample detection signalling means (24) is in travelling belt (20) below, over against the probe (14) of optical sensor.
Above-mentioned automatic analyzer for urine is characterized in that the probe (14) of the fiber optic sensor of this instrument, can be in longitudinal extension, and flexible stroke is 1～5mm.
Above-mentioned automatic analyzer for urine is characterized in that its sample detection signalling means (24),, signal is amplified by integrated operational amplifier as its sensitization end by photo detector, sends the detection strobe pulse by a trigger to CPU again.
Principle of work of the present invention is:
1. on the dry type urine test paper, be soaked with the reagent that this test item is respectively played the sensitive chemical reaction respectively, when this section test paper respectively with after urine contacts, different color demonstrations is promptly arranged, the weight of color is directly proportional with the content of respectively this chemical constitution in the tested urine;
2. the probe of fiber optic sensor, exactly to the test paper of this section colour developing respectively, the test paper of transmitting illuminant bundle scanning colour generation, and accept its folded light beam simultaneously, after decay, homogenizing, light-splitting processing, send monochromator;
3. monochromator only selects the complementary color of color to be measured to pass through, and measures the complementary color intensity variations, can obtain the concentration information of chemical constitution in the sample;
With optical information through photoelectric commutator, become electric signal, after the signal amplifier shaping, become the simulating signal of stable performance;
5. after the CPU in the Control System of Microcomputer accepts above-mentioned simulating signal, calculate by analysis and with machine in the data that store relatively, rapidly, accurately draw the corresponding qualitative and semi-quantitative analysis value of sample, and send printer prints output.
Control System of Microcomputer of the present invention, and have the intelligence such as type of energy decision operation program correctness, self check and this machine of prompting fault state, judgement test paper.
Be applicable to the dry chemical test paper, urine carried out the colorimetric analysis of urobilinogen (Urobilinogen), cholerythrin (Bilirubin), ketoboidies (Ketone body), occult blood (Occult blood), protein (Protein), glucose (Glucose), pH value and nitrite (Nitrous) etc.
Automatic analyzer for urine of the present invention both can detect above-mentioned 8 projects simultaneously, also can be as required, detect respectively wherein 3,4 ...～8.
Detection speed, 120 corpse or other object for laboratory examination and chemical testing sample/h.
The present invention compares with external prior art, has obvious superiority:
1. advanced technology, manufacturing process is easy, and environment for use is less demanding, is fit to national conditions;
2. transmission frequency bandwidth, loss is little, not disturbed by surrounding magnetic field, thereby working stability is reliable;
3. cost is low, uses the homemade automatic analyzer for urine of fiber optic sensor, and its production cost has only external product---using integrating sphere type luminosity sensor or LED array sensor---1/10～1/20;
3. resistance to corrosion is strong, and durability is good, and the life-span is long.
4. price is lower than external like product, is more suitable for widely to intermediate hospital penetrations and promotions such as ground, city, counties.
Facts have proved, automatic analyzer for urine provided by the invention, fast, accurately accurate, flexible, convenient, reached intended purposes of the present invention fully.
The present invention is further elaborated below in conjunction with drawings and Examples:
Fig. 1 is the complete machine structure synoptic diagram of automatic analyzer for urine;
Fig. 2 is the contour structures synoptic diagram of automatic analyzer for urine, and wherein, A is the front, and B is the back;
Fig. 3 is the fiber optic sensor structural representation of automatic analyzer for urine;
Fig. 4 is the sample conveyor structural representation of automatic analyzer for urine;
Fig. 5 is the Control System of Microcomputer logic theory block diagram of automatic analyzer for urine;
Fig. 6 is the system controlled by computer working routine module frame chart of automatic analyzer for urine;
Fig. 7 is the Control System of Microcomputer electrical principle synoptic diagram of automatic analyzer for urine;
Fig. 8 is the power unit electrical principle synoptic diagram of automatic analyzer for urine;
Fig. 9 is the signal amplifier part electrical principle synoptic diagram of automatic analyzer for urine.
Among the figure, (1) is fiber optic sensor; (2) be sample conveyor; (3) be A/D converter (analogue-to-digital converters); (4) be Control System of Microcomputer, adopt the MCS-51 series monolithic, adding certain peripherals forms, for example, external memory storage can be selected series such as 2732,2816 for use, and A/D converter can be selected 0809 series such as grade for use, data latches can be selected series such as 74LS373 for use, integrated gate circuit can be selected series such as 74LS for use, and the crystal oscillator body can be selected 6MHZ series for use, capacitor C
11, C
12Can select 20p for use;
(5) be printer, for example can select the miniature dot matrix printer of TP μ P series parallel port for use; (6) being panel, is man-machine passage to " words ", is the place of instruction input and information output; (7) be machine shell, be divided into cover and base two large divisions, last cover can be a metal, it also can be injection moulding, concentrate the parts that are provided with whole outside contact on it, comprise: printer (5), pilot lamp (10), all kinds of switch (detection, power supply ...) (11), sample input port (9), cartridge fuse (8), useless test paper outlet (52), on the metab, concentrate to settle movement, comprising: host circuit board, power supply, Control System of Microcomputer, fiber optic sensor parts and the sample conveyor etc. that constitute by integrated circuit and discrete component; (12) be instrument light, for example can select 6～12V for use, the instrument light of 50～100W; (13) be fibre-optic bundle, be divided into light source beam and reflected light and accept two kinds of bundles, its structure is: with placing in the wire chamber, is the center by n bundle light transmitting fiber with the light source beam, form a concentric circles, the diameter ratio between the light source beam of combination and reflected light are accepted to restraint with one heart is 0.1～0.5:1～10; (14) being probe, is the sweep unit of optical sensor, is the extension of fibre-optic bundle, is the emission port of light source beam, also is the capture mouth that reflected light is accepted bundle; (15) be monochromator, for example, can select dielectric coating filter for use, wavelength 460～720nm; (16) be photoelectric commutator, for example, can select the photoelectric tube of series such as 2CU5A～C, 2CU79 or 2CU201A～D for use; (17) be signal amplifier, for example, can select integrated operational amplifiers such as LF351, LF353 or LF324 for use. (18) be the shell of fiber optic sensor; (19) being engaged wheel, is the supporter of travelling belt, has several, wherein has one as the wheel of taking that keeps the travelling belt tensity; (20) being travelling belt, is transparent chemical fibre material; (21) being rinse bath, is a hollow box, is wherein loading the foamed material that clean-out system (for example, distilled water or alcohol) soaks, and passage is traversed at its middle part, when travelling belt (20) passes through therebetween, promptly is cleaned; (22) be test paper, for example, can select commercially available dry type urine test paper for use, its structure is on transparent substrate, segmentation is fixed with several, for example, the test paper of 3～8 kinds of different purposes can be respectively applied for the colorimetric analysis of urobilinogen (Uro), cholerythrin (Bil), ketoboidies (Ket), occult blood (blo), protein (Pro), glucose (Glu), pH value and nitrite (Nit) etc. in the people urine; (23) be bracing frame, passage is traversed on its top, is supporting travelling belt (20), and its spacing be able to make travelling belt and test paper pass through; (24) be the sample detection signalling means, it is by P201A～E photoresistance or 2CR81～84 type silicon photocells, and signal demodulator amplifies and trigger is formed, and its position is in travelling belt (20) below, over against the probe (14) of optical sensor; (25) be servomotor, for example, can select SD09 series of servo motor for use; (26) be power unit, form by transformer, RC wave filter, 78 serial voltage stabilizers etc., input AC 220V, 50HZ, output is respectively instrument light and provides and exchange 6～12V power supply, for Control System of Microcomputer provide DC voltage-stabilizing ± 6V ,+the 5V power supply; (27) be that light source drives a termination Control System of Microcomputer, another termination instrument light (12); (28) be to transmit to drive a termination Control System of Microcomputer, another servo motor termination (25); (29) be light homogenizing parts, (30) be light splitting part, (31) be CPU(Central processing unit in the Control System of Microcomputer, central processing unit), adopt the MCS-51 series monolithic, as 8031,8032,8044,8051,8144,80C31,80C252, types such as 8751 are all applicable; (32)～(51) be the signal of instruction and program function, wherein:
(32) be beginning; (33) be the fault autodiagnosis; (34) be the fault diagnosis; (35) be to wait for work order; (36) be that work order is judged; (37) be that time-delay is prepared; (38) be to send to soak the band instruction; (39) be that the reaction of time-delay wait test paper is finished; (40) be to start scanning mechanism; (41) be that the test paper type is judged; (42) be whether the test paper type meets the requirements; (43) be data aggregation; (44) be regression Calculation; (45) be that concentration is calculated; (46) be that report is printed; (47) be to recover instruction; (48) be that the fault type is judged; (49) be that fault information shows; (50) be that information shows; (51) be memoric instruction; Y-has; N-is not; The instruction of B-monocyte sample; The various product instruction of C-.
Component parameters range of choice among Fig. 8:
Transformer specification, BK-100, elementary input AC220V, 0.5A, 50HZ; Secondary output AC12V, 0.1A; AC14V * 2, A; AC12V * 2,3A.
Resistance
R
3220Ω～1.5k、0.5W； R
4240Ω～1k、0.5W。
Electric capacity
C
1, C
2Electrochemical capacitor, 1000～2200 μ F, 50V;
C
3Electrochemical capacitor, 4700 μ F, 50V;
C
4, C
5, C
6Electrochemical capacitor, 470～1000 μ F, 25V;
C
7C
8Electrochemical capacitor, 220～470 μ F, 25V.
Triode
BU
1, BU
2As: BU 407,3AD54A, 3AD55A, 3AD54B or 3AD55B etc.
Diode
D
1Rectification silicon bridge, as: 1J4B41, QSZ3A～6A etc.;
D
2, D
3Commutation diode, as: 6A07,2CZ57A etc.;
D
4Diode, 1N4002～1N4004 etc.;
D
5, D
6Voltage stabilizing diode, as: 2CW7C, 2CW232～236 etc.
Integrated circuit
7815,7915,7805,317 is integrated stable voltage circuit.
Fuse
RD
1, RD
2The minitype fuse seat, the BLX-1 type is joined φ 5 * 18, the 2A fiber tube.
Component parameters range of choice among Fig. 9:
Resistance
R
1～R
61～2MΩ、0.25W；
R
7～R
91～10kΩ、0.25W；
R
10～R
1210～1000kΩ、0.25W；
R
13～R
15100～220Ω、0.25W；
RW
1～RW
32～10kΩ、0.25W；
RW
4～RW
610～47kΩ、0.25W。
Electric capacity
C
1～C
6Leaded multilayer ceramic capacitor, 0.01～0.1 μ F.
Integrated circuit
V
1～V
6As: integrated operational amplifiers such as LF351, LF353 or LF324.
[embodiment one] automatic analyzer for urine
Wherein, the n of the fibre-optic bundle of fiber optic sensor is 3; The diameter ratio that light source beam and reflected light are accepted between the bundle is 0.1:1;
Control System of Microcomputer, adopt 8031 single-chip microcomputers and peripherals thereof in the MCS-51 series to form, for example, external program memory ROM selects 2732 for use, A/D converter selects 0809 for use, and data latches is selected 74LS373 for use, and integrated gate circuit is selected 74LS14,74LS74,74LS02,74LS86 etc. for use, the crystal oscillator body is selected 6MHZ for use, capacitor C
11, C
12Select 20p for use;
Printer is selected the miniature dot matrix printer of TP μ P-16B series parallel port for use;
Instrument light is selected 12V for use, the instrument light of 100W;
Monochromator is selected dielectric coating filter for use, and wavelength is respectively 460nm, 620nm, 720nm;
Photoelectric commutator is selected 2CU201A type silicon photoelectric diode for use;
Signal amplifier is selected the LF351 integrated operational amplifier for use;
Test paper is selected commercially available dry type urine test paper for use,
The sample detection signalling means is selected 2CR81 type silicon photocell, LF353 integrated operational amplifier and d type flip flop for use;
Servomotor is selected SD09 series of servo motor for use;
Sample conveyor is structure as shown in Figure 4 all.
Component parameters range of choice among Fig. 8:
Transformer specification, BK-100, elementary input AC 220V, 0.5A, 50 HZ; Secondary output AC 12V, 0.1A; AC 14V * 2,2A; AC 12V * 2,3A.
Resistance
R
12k、0.25W； R
2100Ω、0.25W；
R
3220Ω、0.5W； R
4240Ω、0.5W。
Electric capacity
C
1, C
2Electrochemical capacitor, 1000 μ F, 50V;
C
3Electrochemical capacitor, 4700 μ F, 50V;
C
4, C
5, C
6Electrochemical capacitor, 470 μ F, 25V;
C
7C
8Electrochemical capacitor, 220 μ F, 25V.
Triode
BU
1、BU
2BU407。
Diode
D
1Rectification silicon bridge, 1J4B41;
D
2, D
3Commutation diode 6A07;
D
4Diode, 1N4004;
D
5, D
6Voltage stabilizing diode, 2CW232.
Integrated circuit
7815,7915,7805,317 is integrated stable voltage circuit.
Fuse
RD
1, RD
2The minitype fuse seat, the BLX-1 type is joined φ 5 * 18, the 2A fiber tube.
Component parameters range of choice among Fig. 9:
Resistance
R
1～R
61MΩ、0.25W；
R
7～R
91kΩ、0.25W；
R
10～R
1210kΩ、0.25W；
R
13～R
15100Ω、0.25W；
RW
1～RW
32kΩ、0.25W；
RW
4～RW
610kΩ、0.25W。
Electric capacity
C
1～C
6Leaded multilayer ceramic capacitor, 0.1 μ F, 50V.
Integrated circuit
V
1～V
6The LF351 integrated operational amplifier.
Detection case is given an example:
Connect localpower, press " starting " key, musical sound rises after 2～6 seconds, the urine test paper pad was immersed in the urine samples to be checked 2 seconds, take out, locate, place on the travelling belt (20) by sample input port (9), this process allows to finish in 12～15 seconds, when the time comes, musical sound ends, simultaneously the CPU(31 in the Control System of Microcomputer) send " startup " instruction to transmitting driving (28), servomotor (25) running in the sample conveyor (2), " regularly " lamp on the panel (6) is bright simultaneously.
(if the urine test paper pad is not served travelling belt (20), timing operation after one week then, printer output " fault " result)
After the urine test paper pad is served travelling belt, operation along with travelling belt, " detection " on the panel, " light source " lamp are bright, the beginning test sample, and test paper is in the following order by probe (14): nitrite, PH, glucose, albumen, occult blood, ketoboidies, cholerythrin, urobilinogen.
During by probe, the sample detection signalling means (24) of travelling belt below is to CPU(31 at respectively this test paper of each sample) send the detection request signal; After respectively the test paper of this sample passed through probe, the sample detection signalling means sent the detection halt signal at the interval of two test paper to CPU; Finish when whole detection of the required project of urine test paper, the sample detection signalling means sends detection to CPU and finishes signal.Urine test paper exports (52) with the useless test paper that travelling belt arrives the shell back side, falls into useless paper box automatically.
Belt remains in operation, and the rinse bath (21) by being located at descending horizontal level cleans it.
Meanwhile, printer is exported testing result under CPU control.
After the printer output testing result, complete machine automatically resets, and successively, " regularly " on the panel, " detection " pilot lamp extinguish, and sample conveyor quits work, and " light source " lamp extinguishes.
If detect again, can press " startup " button again, again start.
In the testing process, when light source beam with irradiate light at a sampling test, in the time of for example on the nitrite test paper, the reflected light of optical sensor is accepted bundle, accepts its reflected light, and reflected light is carried out transmission, homogenizing and the beam split of light by light transmitting fiber.
N-1 after beam split bundle optical channel sends monochromator separately respectively to, and for example, when n was 3, the wavelength of monochromator was respectively 740,610 and 560nm.
When the nitrite test paper color development reacts, will absorb the 560nm wavelength, the nitrite composition is high more in the urine, and corresponding test paper reflected light is dark more, and on the contrary, when this component content hanged down, the test paper reflected light was strong more.
Institute is surveyed the reflected light wavelength, send photoelectric commutator, obtain one group of faint electric signal, after signal amplifier amplified, light signal just became the standard analog magnitude of voltage.
A/D converter changes this analog quantity into digital quantity, send CPU to handle.
Store qualitative, semi-quantitative analysis chart in the CPU working routine, CPU consults this chart automatically, will draw pairing qualitative, the semidefinite value of detection information, send the result to print latch.
Finish when whole detection of the required project of urine test paper, the sample detection signalling means sends detection to CPU and finishes signal.
Meanwhile, printer from print latch, takes out temporal data under CPU control, gather the output testing result.
Also be provided with the continuous working program in this machine CPU inside, when needs continuous detecting urine samples, can be in when start, continuously by twice "start" button, so, when first urine examination is finished, travelling belt stops running.After 2～6 seconds, musical sound gives the correct time once more, repeats boot program, so goes round and begins again, and circulation is operation continuously, and each the detection finished, printer prints result's output, and to the sample automatically ordinal numeration.
[embodiment two] automatic analyzer for urine
Wherein, the n of the fibre-optic bundle of fiber optic sensor is 6; The diameter ratio that light source beam and reflected light are accepted between the bundle is 0.5:10;
After the transmission line of fiber optic sensor changed, the group number of monochromator, photoelectric commutator, signal amplifier also need be done corresponding increase, and it is consistent with the n number of fibre-optic bundle that it increases number.
Control System of Microcomputer, adopt 8051 single-chip microcomputers in the MCS-51 series to do and the peripherals composition, for example, external program memory ROM selects 2732 for use, A/D converter selects 0809 for use, and data latches is selected 74LS373 for use, and integrated gate circuit is selected series such as 74LS14,74LS74,74LS02,74LS86 for use, the crystal oscillator body is selected 6MHZ for use, capacitor C
11, C
12Select 20p for use;
Printer is selected the miniature dot matrix printer of TP μ P-B series parallel port for use;
Instrument light is selected 12V for use, the instrument light of 100W;
Monochromator is selected dielectric coating filter for use, and wavelength is respectively 460,620,720nm;
Photoelectric commutator is selected 2CU201A type silicon photoelectric diode for use;
Signal amplifier is selected the LF353 integrated operational amplifier for use;
Test paper is selected commercially available dry type urine test paper for use,
The sample detection signalling means is selected 2CR81 type silicon photocell, LF353 integrated operational amplifier and d type flip flop for use;
Servomotor is selected SD09 series of servo motor for use;
Sample conveyor such as embodiment one.
Component parameters range of choice among Fig. 8:
Transformer specification, BK-100, elementary input AC 220V, 0.5A, 50HZ; Secondary output AC12V, 0.1A; AC14V * 2,2A; AC12V * 2,3A.
Resistance
R
12k、0.25W； R
2100Ω、0.25W；
R
3220Ω、0.5W； R
4240Ω、0.5W。
Electric capacity
C
1, C
2Electrochemical capacitor, 1000 μ F, 50V;
C
3Electrochemical capacitor, 4700 μ F, 50V;
C
4, C
5, C
6Electrochemical capacitor, 470 μ F, 25V;
C
7C
8Electrochemical capacitor, 220 μ F, 25V.
Triode
BU
1、BU
2BU407。
Diode
D
1Rectification silicon bridge, 1J4B41;
D
2, D
3Commutation diode 6A07;
D
4Diode, 1N4004;
D
5, D
6Voltage stabilizing diode, 2CW232.
Integrated circuit
7815,7915,7805,317 is integrated stable voltage circuit.
Fuse
RD
1, RD
2The minitype fuse seat, the BLX-1 type is joined φ 5 * 18, the 2A fiber tube.
Component parameters range of choice among Fig. 9:
Resistance
R
1～R
61MΩ、0.25W；
R
7～R
91kΩ、0.25W；
R
10～R
1210kΩ、0.25W；
R
13～R
15100Ω、0.25W；
RW
1～RW
32kΩ、0.25W；
RW
4～RW
610kΩ、0.25W。
Electric capacity
C
1～C
6Leaded multilayer ceramic capacitor, 0.1 μ F, 50V.
Integrated circuit
V
1～V
6The LF351 integrated operational amplifier.
Start, detection, program, printing, output, accuracy and detection speed etc. are all with embodiment one, music acoustic control time reading the clock only, by---prepare 2 seconds, sample 12 seconds time limits of input, change into and preparing 4 seconds, sample 13 seconds time limits of input.
[embodiment three] automatic analyzer for urine
Wherein, the n of the fibre-optic bundle of fiber optic sensor is 6; The diameter ratio that light source beam and reflected light are accepted between the bundle is 0.5:10;
Control System of Microcomputer, adopt 80C252 single-chip microcomputer and peripherals thereof in the MCS-51 series to form, for example, external program memory ROM selects 2816 for use, A/D converter selects 0809 for use, and data latches is selected 74LS373 for use, and integrated gate circuit is selected the 74LS series of products for use, the crystal oscillator body is selected 6MHZ for use, capacitor C
11, C
12Select 20p for use;
Printer is selected the miniature dot matrix printer of TP μ P-16A parallel port for use;
Instrument light is selected 3V for use, the halogen tungsten instrument light of 50W;
Monochromator is selected dielectric coating filter for use, wavelength 450,550,650,680,820nm;
Photoelectric commutator is selected 2CU5B type silicon photoelectric diode for use;
Signal amplifier is selected the LF324 integrated operational amplifier for use;
Test paper is selected commercially available dry type urine test paper for use,
The sample detection signalling means is selected P201A photoresistance, LF351 integrated transporting discharging and rest-set flip-flop for use;
Servomotor is selected SD09 series of servo motor for use;
Component parameters range of choice among Fig. 8:
Transformer specification is with embodiment one;
Resistance is the RJ metalfilmresistor, wherein:
R
15.1k、0.25W； R
2560Ω、0.25W；
R
31.5k、0.25W； R
41k、0.25W。
Electric capacity
C
1, C
2Electrochemical capacitor, 2200 μ F, 50V;
C
3Electrochemical capacitor, 4700 μ F, 50V;
C
4, C
5, C
6Electrochemical capacitor, 1000 μ F, 25V;
C
7, C
8Electrochemical capacitor, 470 μ F, 25V.
Triode
BU
1, BU
2Select 3AD54A for use;
Diode
D
1Rectification silicon bridge is selected QSZ3A for use;
D
2, D
3Commutation diode is selected 2CZ57A for use;
D
4Diode, 1N4002;
D
5, D
6Voltage stabilizing diode is selected 2CW234 for use.
Integrated circuit
7815,7915,7805,317 is integrated stable voltage circuit.
Fuse such as embodiment one.
Component parameters range of choice among Fig. 9:
Resistance
R
1～R
32M Ω, R
4～R
61M Ω, R
7～R
910k Ω, R
10～R
121000k Ω, R
13～R
15220 Ω, RW
1～RW
310k Ω, RW
4～RW
647k Ω, above resistance are 0.25W.
Electric capacity
C
1～C
6Leaded multilayer ceramic capacitor, 0.01 μ F.
Integrated circuit
V
1～V
6Select the LF324 integrated operational amplifier for use.
Sample conveyor such as embodiment one.
Start, detection, program, printing, output, accuracy and detection speed etc. are all with embodiment one, music acoustic control time reading the clock only, by---prepare 2 seconds, sample 12 seconds time limits of input, change into and preparing 6 seconds, sample 15 seconds time limits of input.
Claims (10)
1, a kind of is that main body constitutes by micro-processor controlled optical sensor and sample conveyor, belongs to the medical detecting Instrument category, and automatic analyzer for urine is characterized in that:
1.1. machine shell is divided into cover and base two large divisions,
1.1.1. the parts that are provided with whole outside contact are concentrated in the outside of last cover, comprising: printer (5), all kinds of pilot lamp (10), all kinds of switch (11), sample input port (9), cartridge fuse (8), useless test paper outlet (52) etc.,
1.1.2. on the base of metal material, concentrate and settle movement, comprising:
Host circuit board, power supply, Control System of Microcomputer, fiber optic sensor parts and the sample conveyor etc. that constitute by integrated circuit and discrete component,
1.2. Control System of Microcomputer is made up of MCS-51 series monolithic, external storage, A/D converter, data latches, crystal oscillator body, integrated circuit and discrete component,
1.3. optical sensor adopts fiber optic sensor (1),
1.4. sample conveyor (2) is that the travelling belt (20) of circular flow carries sample to be detected (22), one by one by fixing optic probe (14).
2, according to the described automatic analyzer for urine of claim 1, the fiber optic sensor that it is characterized in that this instrument is that sequence unit instrument light (12), fibre-optic bundle (13), monochromator (15), photoelectric commutator (16) and signal amplifier (17) in metal shell (18).
3,, it is characterized in that in the fiber optic sensor of this instrument according to the described automatic analyzer for urine of claim 1:
3.1. power supply (26) is powered to instrument light (12),
3.2. the emission light of instrument light (12) is through fibre-optic bundle (13) directive sample to be detected (22), reflected light after probe (14) capture and process monochromator (15) are handled, become electric signal through photoelectric commutator (16), output terminal through (16) links to each other with the input end of signal amplifier (17)
3.3. the simulating signal that amplifier produces, the output terminal through (17) is by the CPU of A/D converter (3) input Control System of Microcomputer.
4, according to the described automatic analyzer for urine of claim 1, it is characterized in that the fibre-optic bundle (13) in the fiber optic sensor of this instrument, be divided into light source beam and reflected light and accept two kinds of bundles, its structure is: placed in the wire chamber together by n bundle light transmitting fiber, with the light source beam is the center, forms a concentric circles.
5,, it is characterized in that in the fibre-optic bundle (13) of the fiber optic sensor of this instrument according to the described automatic analyzer for urine of claim 1:
5.1. the light source from instrument light over against instrument light (12), is accepted in the upper end of light source beam, sample to be detected (22) is scanned by probe (14) in the lower end,
5.2. reflected light is accepted an end of bundle and captured the sample reflected light by probe (14), the other end is divided into n-1 optical channel, send monochromator (15) with reflected light,
6,, it is characterized in that in the fibre-optic bundle (13) of the fiber optic sensor of this instrument that the diameter ratio between the light source beam of combination and reflected light are accepted to restraint with one heart is 0.1～0.5:1～10 according to the described automatic analyzer for urine of claim 1.
7, according to the described automatic analyzer for urine of claim 1, the sample conveyor that it is characterized in that this instrument is to be made up of servomotor (25), engaged wheel (19), travelling belt (20), bracing frame (23), rinse bath (21) and sample detection signalling means (24).
8,, it is characterized in that the sample conveyor of this instrument is according to the described automatic analyzer for urine of claim 1
8.1. servomotor (25) drives driving-belt (20), in engaged wheel (19) intercropping circular flow,
8.2. passage is traversed on the top of bracing frame (23), is supporting travelling belt (20), its spacing be able to make travelling belt and test paper pass through,
8.3. passage is traversed at the middle part of rinse bath (21), travelling belt (20) passes through therebetween,
8.4. the position of sample detection signalling means (24) is in travelling belt (20) below, over against the probe (14) of optical sensor.
9, according to the described automatic analyzer for urine of claim 1, it is characterized in that the probe (14) of the fiber optic sensor of this instrument, can be in longitudinal extension, flexible stroke is 1～5mm.
10, according to the described automatic analyzer for urine of claim 1, the sample detection signalling means (24) that it is characterized in that this instrument,, signal is amplified as its sensitization end by photo detector, send the detection strobe pulse by a trigger to CPU again by integrated operational amplifier.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 91231857 CN2109570U (en) | 1991-12-21 | 1991-12-21 | Automatic analyser for urine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 91231857 CN2109570U (en) | 1991-12-21 | 1991-12-21 | Automatic analyser for urine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2109570U true CN2109570U (en) | 1992-07-08 |
Family
ID=4937013
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 91231857 Granted CN2109570U (en) | 1991-12-21 | 1991-12-21 | Automatic analyser for urine |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2109570U (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1967251B (en) * | 2005-11-15 | 2012-07-04 | 霍夫曼-拉罗奇有限公司 | System and method for examining a liquid sample |
| CN103592246A (en) * | 2013-11-22 | 2014-02-19 | 武汉友芝友医疗科技有限公司 | Body fluid pH value test method and device |
| CN103926237A (en) * | 2014-04-16 | 2014-07-16 | 爱威科技股份有限公司 | Dry chemical detection device |
-
1991
- 1991-12-21 CN CN 91231857 patent/CN2109570U/en active Granted
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1967251B (en) * | 2005-11-15 | 2012-07-04 | 霍夫曼-拉罗奇有限公司 | System and method for examining a liquid sample |
| CN103592246A (en) * | 2013-11-22 | 2014-02-19 | 武汉友芝友医疗科技有限公司 | Body fluid pH value test method and device |
| CN103926237A (en) * | 2014-04-16 | 2014-07-16 | 爱威科技股份有限公司 | Dry chemical detection device |
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