CN210914320U - A mechanism is got to perforated plate clamp for cell culture - Google Patents
A mechanism is got to perforated plate clamp for cell culture Download PDFInfo
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- CN210914320U CN210914320U CN201921633582.1U CN201921633582U CN210914320U CN 210914320 U CN210914320 U CN 210914320U CN 201921633582 U CN201921633582 U CN 201921633582U CN 210914320 U CN210914320 U CN 210914320U
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Abstract
The utility model discloses a multi-hole plate clamping mechanism for cell culture, which comprises a static clamping plate and a dynamic clamping plate, wherein the dynamic clamping plate can be close to the static clamping plate through a driving component so as to clamp multi-hole plates; the dynamic clamping plate is provided with a clamping groove for embedding the porous plate, and the static clamping plate is provided with a pressure sensor for detecting the clamping force applied to the porous plate; static splint with the developments splint are connected with lifting unit jointly to the lifting the perforated plate. The utility model discloses can control and adjust the clamping-force.
Description
Technical Field
The utility model relates to the fields of bioengineering, medical instrument, machine-building etc, concretely relates to a perforated plate clamp is got for cell culture.
Background
The cell culture plate is widely applied to the fields of medical treatment, bioengineering and the like, and is divided into a Terasaki plate and a common cell culture plate according to different materials, and the number of culture holes is 6, 12, 24, 48, 96, 384, 1536 holes and the like; during the application process, the cell culture plate is frequently moved and the reaction liquid is extracted or injected, and in order to ensure a sterile environment, mechanical clamping jaws are mostly adopted for operation.
The existing mechanical clamping jaw mainly takes an air cylinder as a power element to clamp a cell culture plate, and the clamping force of the pneumatic clamping jaw cannot be accurately adjusted; in actual operation, the clamping force is too large, so that the plate is deformed, and liquid is leaked or the cell culture plate is damaged.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is to provide a mechanism is got to perforated plate clamp for cell culture, it can control and adjust the clamping-force.
In order to solve the technical problem, the utility model provides a multi-hole plate clamping mechanism for cell culture, which comprises a static clamping plate and a dynamic clamping plate, wherein the dynamic clamping plate can be close to the static clamping plate through a driving component to clamp the multi-hole plate; the dynamic clamping plate is provided with a clamping groove for embedding the porous plate, and the static clamping plate is provided with a pressure sensor for detecting the clamping force applied to the porous plate; static splint with the developments splint are connected with lifting unit jointly to the lifting the perforated plate.
Furthermore, an adjusting component for clamping the porous plate is arranged in the clamping groove, the adjusting component comprises symmetrically arranged support arms and at least two elastic pieces, the two support arms are obliquely arranged, and the distance between the two support arms is increased along the direction close to the static clamping plate; the two support arms are rotatably connected with the dynamic clamping plate and are respectively in contact with the inner wall of the clamping groove through the elastic piece.
Further, the lifting assembly comprises a first platform and a first screw rod, and the first platform is in threaded connection with the first screw rod; the static clamping plate and the dynamic clamping plate are connected with the first platform.
Further, the driving assembly comprises a second platform, a first sliding block and a second screw rod, and the first sliding block is in threaded connection with the second screw rod; the static clamping plate is fixedly connected with the second platform, and the dynamic clamping plate is connected with the second platform in a sliding mode through the first sliding block.
Furthermore, the lifting assembly comprises a third platform, a first gear and a first rack meshed with the first gear, the third platform is fixedly connected with the first rack, and the static clamping plate and the dynamic clamping plate are both connected with the third platform.
Further, the driving assembly comprises a fourth platform, a second sliding block, a second gear and a second rack meshed with the second gear; the static clamping plate is fixedly connected with the fourth platform, and the dynamic clamping plate is connected with the second rack through the second sliding block so as to drive the dynamic clamping plate to be close to the static clamping plate by utilizing the meshing of the second gear and the second rack.
Furthermore, the free end of the support arm is arranged in an arc shape.
Furthermore, the opening end of the clamping groove is arranged in a chamfer angle mode.
The utility model has the advantages that:
the static clamping plate is provided with a pressure sensor, the clamping force applied to the perforated plate by the static clamping plate and the dynamic clamping plate is adjusted through the numerical feedback of the pressure sensor, negative feedback is formed, the position of the dynamic clamping plate is adjusted in real time, and the cell culture plate is prevented from being damaged in the clamping process; the structure is simple and reliable, and is easy to control.
Drawings
Fig. 1 is a first schematic structural diagram of the present invention;
FIG. 2 is a second schematic structural diagram of the present invention;
fig. 3 is an enlarged view of a portion a in fig. 2.
The reference numbers in the figures illustrate: 1. a static splint 11, a pressure sensor; 2. a dynamic splint; 21. a card slot; 31. a support arm; 32. an elastic member; 41. a first platform; 42. a first lead screw; 51. a second platform; 52. a second lead screw; 53. and a second slider.
Detailed Description
The present invention is further described with reference to the following drawings and specific embodiments so that those skilled in the art can better understand the present invention and can implement the present invention, but the embodiments are not to be construed as limiting the present invention.
Referring to fig. 1 and 2, an embodiment of a mechanism is got to perforated plate clamp for cell culture of the utility model, including static splint 1 and the dynamic splint 2 that are used for pressing from both sides to get the perforated plate, dynamic splint 2 is close to or keeps away from static splint 1 through drive assembly to press from both sides and get or release the perforated plate. Simultaneously static splint 1 and dynamic splint 2 are connected with lifting unit jointly to utilize lifting unit to take the motion of static splint 1 and dynamic splint 2, carry required height with the perforated plate.
Referring to fig. 1 to 3, the dynamic splint 2 is provided with a slot 21 for inserting the edge of the porous plate, so that the porous plate is inserted between the dynamic splint 2 and the static splint 1. The porous plate in the prior art has multiple specifications, and in order to increase the type of the adaptation of the clamping mechanism, an adjusting component is arranged inside the clamping groove 21 and comprises a support arm 31 and at least two elastic pieces 32 which are symmetrically arranged. One end of each of the two support arms 31 is inserted into the inside of the slot 21 and is rotatably connected with the dynamic splint 2, and the free end of each of the two support arms 31 faces the static splint 1. The two arms 31 are inclined, and the distance between the free ends of the two arms 31 is greater than the distance between the hinged ends thereof. The elastic pieces 32 are arranged between the two support arms 31 and the inner walls of the clamping grooves 21, the elastic force of the elastic pieces 32 can be used for increasing the specification of the clamping assembly, meanwhile, the elastic pieces 32 can also be used for applying acting force to the porous plate, and the stability of clamping is improved. The elastic member 32 may be a spring, an elastic block, an elastic sheet, or the like. In addition, the perforated plates in the prior art can be divided into sections according to the specification and the size, the perforated plates in the same section can be adjusted through the elastic pieces 32, and the perforated plates in different sections can be adjusted through replacing the dynamic clamping plates 2.
Referring to fig. 1 to 3, the open end of the slot 21 is chamfered to facilitate the insertion of the porous plate. In order to increase the contact area between the arms 31 and the perforated plate, the free ends of the arms 31 are curved. In addition, the free ends of the two arms 31 may be attached with friction pads or the like to increase the friction between the arms 31 and the perforated plate.
Referring to fig. 1 and 2, the lifting assembly includes a first platform 41 and a first lead screw 42, the first lead screw 42 penetrates through the first platform 41, and the first platform 41 is in threaded connection with the first lead screw 42. The static splint 1 and the dynamic splint 2 are both disposed on the first platform 41, and the first screw rod 42 is connected with a servo motor. When the first screw rod 42 is driven by the servo motor, the first platform 41 can be driven to move, so that the porous plate clamped between the static clamping plate 1 and the dynamic clamping plate 2 is lifted to a required position.
Referring to fig. 1 and 2, the driving assembly includes a second platform 51, a first slider and a second lead screw 52, and the first slider and the second lead screw 52 are threadedly coupled. The static splint 1 is vertically fixed with the second platform 51, and the dynamic splint 2 is connected with the second platform 51 in a sliding way through the first slide block. The second screw 52 is connected with a servo motor, the servo motor is used for driving the second screw 52 to rotate, and the dynamic clamping plate 2 is driven to be close to the static clamping plate 1 through the thread fit between the first sliding block and the second screw 52, so that the clamping force applied to the porous plate is increased.
Referring to fig. 1, in another embodiment, the lifting assembly includes a third platform, a first gear and a first gear, the first gear is engaged with a first rack, and the third platform is fixedly connected with the first rack so that the third platform can be driven to move by the first gear. Static splint 1 and dynamic splint 2 all set up on above-mentioned third platform, and first gear connection has servo motor. When the first gear is driven by the servo motor, the third platform can be driven to move, so that the porous plate clamped between the static clamping plate 1 and the dynamic clamping plate 2 is lifted to a required position.
Referring to fig. 1, the driving assembly includes a fourth platform, a second slider 53, a second gear and a second rack, the second gear is engaged with the second rack, the static splint 1 is vertically fixed to the fourth platform, and the dynamic splint 2 is slidably connected to the fourth platform through the second slider 53. The second gear is connected with a servo motor, the servo motor is used for driving the second gear to rotate, and the dynamic clamping plate 2 is driven to be close to the static clamping plate 1 through the matching between the second rack and the second gear so as to increase the clamping force applied to the porous plate.
Referring to fig. 1, a pressure sensor 11 is provided on the static splint 1, and the pressure sensor 11 is preferably a film pressure sensor 11 in this embodiment. The pressure sensor 11 is electrically connected with a controller, and the servo motors are electrically connected with the controller so as to adjust the clamping force applied to the porous plate by the static clamping plate 1 and the dynamic clamping plate 2 through the numerical feedback of the pressure sensor 11.
A test method using the multi-plate clamping mechanism for cell culture comprises the following steps:
s1, testing the clamping force corresponding to the critical position of the elastic strain and the yield strain of the porous plate, and recording as T0;
s2, when the porous plate is clamped by the static clamping plate 1 and the dynamic clamping plate 2, the value of the pressure sensor 11 is continuously increased from 0, the test value of the pressure sensor 11 is recorded as T1, and T1 is greater than 0;
s3, when the T1 is less than T0, the clamping force is not enough to clamp the porous plate, and the servo motor continues to rotate positively to drive the dynamic clamping plate 2 to clamp the porous plate gradually; to increase the clamping force exerted on the perforated plate;
s4, when the clamping force exceeds the critical value of elastic strain when T1> T0, the perforated plate is easy to generate yield strain, and the processor sends a feedback signal to the servo motor to enable the servo motor to rotate reversely so as to reduce the clamping force applied to the perforated plate;
and S5, when the T1 is T0, the lifting assembly can drive the static clamping plate 1 and the dynamic clamping plate 2 to move so as to lift the porous plate.
The above-mentioned embodiments are merely preferred embodiments for fully illustrating the present invention, and the scope of the present invention is not limited thereto. Equivalent substitutes or changes made by the technical personnel in the technical field on the basis of the utility model are all within the protection scope of the utility model. The protection scope of the present invention is subject to the claims.
Claims (8)
1. The multi-hole plate clamping mechanism for cell culture is characterized by comprising a static clamping plate and a dynamic clamping plate, wherein the dynamic clamping plate can be close to the static clamping plate through a driving assembly so as to clamp a multi-hole plate; the dynamic clamping plate is provided with a clamping groove for embedding the porous plate, and the static clamping plate is provided with a pressure sensor for detecting the clamping force applied to the porous plate; static splint with the developments splint are connected with lifting unit jointly to the lifting the perforated plate.
2. The multi-plate clamping mechanism for cell culture as claimed in claim 1, wherein an adjusting component for clamping the multi-plate is arranged in the clamping groove, the adjusting component comprises symmetrically arranged support arms and at least two elastic members, the two support arms are obliquely arranged, and the distance between the two support arms increases along the direction close to the static clamping plate; the two support arms are rotatably connected with the dynamic clamping plate and are respectively in contact with the inner wall of the clamping groove through the elastic piece.
3. The multi-plate clamping mechanism for cell culture as claimed in claim 1, wherein the lifting assembly comprises a first platform and a first screw rod, and the first platform is in threaded connection with the first screw rod; the static clamping plate and the dynamic clamping plate are connected with the first platform.
4. The multi-plate clamping mechanism for cell culture as claimed in claim 1, wherein the driving assembly comprises a second platform, a first slide block and a second screw rod, and the first slide block and the second screw rod are connected by screw threads; the static clamping plate is fixedly connected with the second platform, and the dynamic clamping plate is connected with the second platform in a sliding mode through the first sliding block.
5. The multi-plate gripper mechanism for cell culture according to claim 1, wherein the lifting assembly comprises a third platform, a first gear and a first rack engaged with the first gear, the third platform and the first rack are fixedly connected, and the static clamping plate and the dynamic clamping plate are both connected to the third platform.
6. The multi-plate clamping mechanism for cell culture according to claim 5, wherein the driving assembly comprises a fourth platform, a second slider, a second gear and a second rack engaged with the second gear; the static clamping plate is fixedly connected with the fourth platform, and the dynamic clamping plate is connected with the second rack through the second sliding block so as to drive the dynamic clamping plate to be close to the static clamping plate by utilizing the meshing of the second gear and the second rack.
7. The multi-plate gripper mechanism for cell culture according to claim 2, wherein the free ends of the arms are arranged in an arc shape.
8. The multi-plate gripper according to claim 1, wherein the open ends of the engaging grooves are chamfered.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921633582.1U CN210914320U (en) | 2019-09-27 | 2019-09-27 | A mechanism is got to perforated plate clamp for cell culture |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921633582.1U CN210914320U (en) | 2019-09-27 | 2019-09-27 | A mechanism is got to perforated plate clamp for cell culture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210914320U true CN210914320U (en) | 2020-07-03 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921633582.1U Active CN210914320U (en) | 2019-09-27 | 2019-09-27 | A mechanism is got to perforated plate clamp for cell culture |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210914320U (en) |
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2019
- 2019-09-27 CN CN201921633582.1U patent/CN210914320U/en active Active
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| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20210113 Address after: Room C309, South third floor, huanxiuhu building, high speed rail new town, Xiangcheng District, Suzhou City, Jiangsu Province Patentee after: Suzhou WeiPai Medical Technology Co.,Ltd. Address before: 215000 South 3rd and 4th Floors of Huanxiuhu Building, Xiangcheng High-speed Railway New Town, Suzhou City, Jiangsu Province Patentee before: JIANGSU JICUI MICRO-NANO AUTOMATION SYSTEM AND EQUIPMENT TECHNOLOGY RESEARCH INSTITUTE Co.,Ltd. |
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| TR01 | Transfer of patent right |