CN210875396U - Droplet generator and droplet transfer mechanism - Google Patents
Droplet generator and droplet transfer mechanism Download PDFInfo
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- CN210875396U CN210875396U CN201921616829.9U CN201921616829U CN210875396U CN 210875396 U CN210875396 U CN 210875396U CN 201921616829 U CN201921616829 U CN 201921616829U CN 210875396 U CN210875396 U CN 210875396U
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Abstract
The utility model relates to a droplet generates appearance and droplet transfer mechanism, droplet transfer mechanism includes: droplet tray, liquid receiving tray, positioning piece and liquid transferring piece. Above-mentioned droplet transfer mechanism is when using, will be used for producing the droplet chip of droplet and place on the droplet tray, simultaneously, connect liquid tray and droplet tray to correspond and place, guarantee that the little dropping liquid can follow the microdroplet hole in shorter distance and drip the pipette to avoid droplet liquid skew to appear in the whereabouts in-process. The pipette is firstly placed on the liquid-moving piece, then the liquid-moving piece moves according to the corresponding position where the microdroplet hole marked by the positioning piece is located, and when the liquid-moving piece moves to the marking position of the positioning piece, the mutual contraposition of the pipette and the microdroplet hole is realized. Compared with the method that the positioning is performed manually by directly adopting a liquid dropping gun, the embodiment realizes auxiliary positioning of the pipette by the positioning piece, and simultaneously limits the distance between the micro-droplet hole and the end part of the pipette, so that the micro-droplet can be accurately dropped into the pipette.
Description
Technical Field
The utility model relates to a DNA detects's technical field, especially relates to a droplet generates appearance and droplet transfer mechanism.
Background
At present, the Digital PCR (Digital PCR-dPCR) technology is a new nucleic acid detection and quantification method, and is required before detection. In the detection, firstly, droplets (a technology that immiscible liquid in a microfluidic droplet chip generates uniform droplets meeting various size requirements at a very high speed) are generated in a transfer head, and then the transfer head after the droplets is put into a reaction instrument for PCR treatment. However, when the pipette is subjected to microdroplets, the pipette is often operated by manually controlling the pipette gun, and due to the small orifice of the pipette, microdroplets cannot accurately enter the pipette, so that the phenomenon of wall adhesion (microdroplets are retained on the tube wall of the pipette) or omission occurs, and the detection result of the PCR is affected.
Disclosure of Invention
In view of the above, there is a need for a droplet generator and droplet transfer mechanism that can accurately drop droplets into a pipette.
The technical scheme is as follows:
a droplet transfer mechanism comprising: droplet tray, connect liquid tray, setting element and move liquid piece, the microdroplet has been seted up on the droplet tray, just place the droplet chip that is used for the droplet on the droplet tray, connect the liquid tray with the droplet tray corresponds the setting, just connect be equipped with on the liquid tray with the corresponding positioning portion in microdroplet, move liquid piece and be used for installing the pipette, it movably installs to move liquid piece on the positioning portion, the setting element is used for the mark the corresponding position in microdroplet, move liquid piece edge the setting element removes.
When the droplet transfer mechanism is used, a droplet chip for generating droplets is placed on the droplet tray, and meanwhile, the liquid receiving tray and the droplet tray are correspondingly placed (for example, the liquid receiving tray and the droplet tray are mutually overlapped and matched or approximately overlapped and matched), so that the droplets can be ensured to be dropped into a pipette from a droplet hole within a short distance, and the droplets are prevented from being deviated in the falling process. The pipette is firstly placed on the liquid-moving piece, then the liquid-moving piece moves according to the corresponding position where the microdroplet hole marked by the positioning piece is located, and when the liquid-moving piece moves to the marking position of the positioning piece, the mutual contraposition of the pipette and the microdroplet hole is realized. Compared with the method that the positioning is manually performed by directly adopting the dripping gun (namely, the output end of the dripping gun is aligned with the end of the pipette), the embodiment realizes auxiliary positioning of the pipette by the positioning piece, and simultaneously limits the distance between the microdroplet hole and the end of the pipette, so that the microdroplet can be accurately dripped into the pipette.
A droplet generator comprises the droplet transfer mechanism, a box, a droplet generating component and a droplet chip, wherein the droplet transfer mechanism is arranged in the box, the droplet chip is arranged on the droplet tray, and the droplet generating component is matched with the droplet chip in a mounting way.
When the micro-droplet generator is used, micro-droplets are generated inside the box body, and the pollution of external impurities to micro-droplets can be effectively avoided. The micro-droplet chip is mounted and matched through the micro-droplet generating component, namely, the micro-droplet chip generates micro-droplets through the micro-droplet generating component. At this point, the droplet passes through the droplet orifice of the droplet transfer mechanism and into the pipette. The micro-droplet transfer mechanism realizes auxiliary positioning of the pipette by means of the positioning piece, and simultaneously limits the distance between the micro-droplet hole and the end part of the pipette, so that micro-droplets can be accurately dripped into the pipette.
The technical solution is further explained below:
the micro-droplet tray is provided with a plurality of micro-droplet holes corresponding to the micro-droplet chips, the liquid-transferring pieces are multiple, the positioning pieces are used for marking the positions of the micro-droplet holes, and the liquid-transferring pieces move to the marking positions of the positioning pieces in a one-to-one correspondence manner on the positioning portions.
The droplet generator further comprises a first driving piece and a second driving piece, the droplet tray and the liquid receiving tray are movably arranged in the box body through the operation opening, the first driving piece is connected with the droplet tray, and the second driving piece is connected with the liquid receiving tray.
The droplet generation assembly is located inside the box body and comprises an air conveying pipe, a pressurizing piece and a pressurizing plate, the air conveying pipe and the pressurizing piece are connected with the pressurizing plate, and the pressurizing plate corresponds to the droplet chip on the droplet tray.
The droplet chip is provided with a plurality of droplet generating parts at intervals, and the droplet holes formed in the droplet tray are correspondingly communicated with the droplet generating areas.
The micro-droplet generation area comprises an oil cavity hole, an air cavity hole and a micro-droplet generation hole, the micro-droplet generation hole is communicated with the micro-droplet hole, the pressurizing plate is provided with an oil-air spray head corresponding to the oil cavity hole, and the pressurizing plate is provided with an air-water spray head corresponding to the air cavity hole; when the oil gas shower nozzle inserts oil pocket hole, and aqueous vapor shower nozzle inserts when the air pocket hole, the microdroplet generates the hole and produces the microdroplet and passes through the microdroplet hole drips out.
The droplet generator also comprises an air supply part, a first shunt pipe and a second shunt pipe, wherein a first pressure regulating valve is arranged on the first shunt pipe, a second pressure regulating valve is arranged on the second shunt pipe, one end of the first shunt pipe and one end of the second shunt pipe are both communicated with the air conveying pipe, the other end of the first shunt pipe is communicated with the oil-gas spray head, and the second shunt pipe is communicated with the water-gas spray head.
The droplet generator further comprises a third driving piece, the third driving piece is located on the liquid receiving tray, the position adjusting portion comprises a sliding rail, the liquid transferring piece is slidably arranged on the sliding rail, and the third driving piece drives the liquid transferring piece to move along the sliding rail.
The droplet generator also comprises a collecting plate, wherein a pre-storing port is formed in the collecting plate, and the size of the opening of the pre-storing port is consistent with that of the pipe orifice of the pipette.
Drawings
Fig. 1 is a schematic structural view of a droplet transfer mechanism according to an embodiment of the present invention;
fig. 2 is a schematic view of a droplet transfer mechanism according to another embodiment of the present invention;
fig. 3 is a schematic structural view of a droplet generator according to an embodiment of the present invention;
fig. 4 is a schematic diagram of a droplet generation assembly according to an embodiment of the present invention;
fig. 5 is an enlarged schematic structural diagram of a droplet generating assembly according to an embodiment of the present invention.
Description of reference numerals:
100. the micro-droplet tray comprises a micro-droplet tray body, 110, a micro-droplet chip, 111, a micro-droplet generation area, 1111, an oil cavity hole, 1112, an air cavity hole, 1113, a micro-droplet generation hole, 200, a liquid receiving tray body, 210, a positioning part, 211, a sliding rail, 300, a positioning part, 400, a liquid transferring part, 410, a pipette, 500, a box body, 510, a first driving part, 520, a second driving part, 530, a third driving part, 600, a micro-droplet generation assembly, 610, an air conveying pipe, 620, a pressurizing part, 630, a pressurizing plate, 631, an oil and gas nozzle, 632, a water and gas nozzle, 640, an air supply part, 650, a first shunt pipe, 651, a first pressure regulating valve, 660, a second shunt pipe, 661, a second pressure regulating valve, 700, a collecting plate.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention will be further described in detail with reference to the accompanying drawings and the following detailed description. It should be understood that the detailed description and specific examples, while indicating the scope of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not represent the only embodiments.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
In the present invention, the terms "first" and "second" do not denote any particular quantity or order, but are merely used to distinguish names.
In one embodiment, as shown in fig. 1 and 2, a droplet transfer mechanism comprises: droplet tray 100, connect liquid tray 200, setting element 300 and move liquid piece 400, the microdroplet has been seted up on the droplet tray 100, just placed the droplet chip 110 that is used for the microdroplet on the droplet tray 100, connect liquid tray 200 with droplet tray 100 corresponds the setting, just connect be equipped with on the liquid tray 200 with the position adjusting part 210 that the microdroplet corresponds, it is used for installing pipette 410 to move liquid piece 400, it installs movably to move liquid piece 400 on position adjusting part 210, setting element 300 is used for the mark the corresponding position in microdroplet, it follows to move liquid piece 400 setting element 300 removes.
When the droplet transfer mechanism is used, the droplet chip 110 for generating droplets is placed on the droplet tray 100, and at the same time, the liquid receiving tray 200 is placed corresponding to the droplet tray 100 (for example, the liquid receiving tray 200 and the droplet tray 100 are in a mutually-overlapped fit or approximately-overlapped fit), so that droplets can be dropped into the pipette 410 from a droplet hole within a short distance, and thus, the droplet liquid is prevented from being deviated during the dropping process. The pipette 410 is first placed on the pipetting device 400, and then the pipetting device 400 moves according to the corresponding position marked by the positioning device 300, so that when the pipetting device 400 moves to the mark of the positioning device 300, the pipette 410 and the microdroplet are aligned with each other. Compared with the method of manually aligning the dispensing gun (i.e. aligning the output end of the dispensing gun with the end of the pipette 410), the above embodiment relies on the positioning member 300 to position the pipette 410, and at the same time, limits the distance between the droplet hole and the end of the pipette 410, so as to accurately drop droplets into the pipette 410.
In one embodiment, the positioning member 300 is a flexible rope or a telescopic rod. The pipetting piece 400 is a well plate or a tube rack. That is, the transfer unit 400 can select one or more pipettes 410 to be mounted on the transfer unit 400 according to the actual processing conditions. When only one droplet opening is provided in the droplet tray 100. The initial location of the placement member 300 on the droplet tray 100 is determined and the location of the droplet orifices on the placement member 300 is then marked. When the pipetting device 400 is moved, the starting point of the positioning device 300 is aligned with the starting end of the droplet tray 100, in this embodiment, the droplet tray 100 is a rectangular parallelepiped, and the positioning device 300 is a flexible cord. I.e., when the positioning member 300 is in a stretched state, the positioning member 300 is parallel to the long side of the droplet tray 100. The pipetting device 400 is moved on the positioning part 210 to the marking position of the positioning device 300, and when the pipetting device 400 reaches the marking position, the pipettes 410 placed on the pipetting device 400 are aligned with the wells. For example: when the positioning member 300 is a telescopic rod, the positions of the micro well are marked on the telescopic rod, and then the pipetting member 400 can be moved along the marked positions of the telescopic rod.
In one embodiment, the droplet tray 100 is provided with a plurality of the micro-drop holes corresponding to the droplet chip 110, the pipetting member 400 is provided with a plurality of the positioning members 300, the positioning members 300 are used for marking the positions of the plurality of micro-drop holes, the pipetting member 400 moves to the marking positions of the positioning members 300 on the positioning portion 210 in a one-to-one correspondence manner, specifically, according to the actual processing environment, the droplet tray 100 is provided with a plurality of micro-drop holes, that is, the plurality of micro-drop holes are arranged in a matrix, at this time, the pipetting member 400 is provided with a plurality of the pipettes 410, so that the pipetting member 400 can realize one pipette 400 corresponding to one row of micro-drop holes only by moving at one degree of freedom, for example, when the matrix of the micro-drop holes is a region of 12 × 8 (row × row), at this time, the pipetting member 400 is provided with 8 pipettes 410, further, when the positioning members 300 are marked with positions, the positioning members 300 are determined according to the spacing between two adjacent micro-drop holes, the positioning members 300 are positioned at the spacing between the positioning members 300, and the positioning members 300 can be connected to the positioning members 300 in a straight line, and the positioning members 300 can be realized by using a flexible positioning cord.
As shown in fig. 1 to 3, in one embodiment, a droplet generator includes a droplet transfer mechanism according to any of the above embodiments, and further includes a housing 500, a droplet generation assembly 600, and a droplet chip 110, the droplet transfer mechanism is installed inside the housing 500, the droplet chip 110 is installed on the droplet tray 100, and the droplet generation assembly 600 is installed and matched with the droplet chip 110.
When the micro-droplet generator is used, micro-droplets are generated inside the box body 500, and the pollution of external impurities to the micro-droplets can be effectively avoided. The droplet generation module 600 is used to mount and cooperate with the droplet chip 110, that is, the droplet generation module 600 is used to generate droplets on the droplet chip 110. At this point, the droplet passes through the droplet orifice of the droplet transfer mechanism and into the pipette 410. The droplet transfer mechanism is assisted by the positioning member 300 to position the pipette 410, and at the same time, the distance between the droplet hole and the end of the pipette 410 is limited, so that the droplet can be accurately dropped into the pipette 410.
As shown in fig. 1 and 2, in one embodiment, the droplet generator further includes a first drive 510 and a second drive 520. The droplet tray 100 and the liquid receiving tray 200 are movably installed in the box 500 through the operation opening, and the first driving member 510 is connected to the droplet tray 100, and the second driving member 520 is connected to the liquid receiving tray 200. Specifically, the first driving member 510 and the second driving member 520 are motors or telescopic cylinders. In order to ensure the sealing performance of the droplet generator itself, a first baffle is disposed on the side of the droplet tray 100 facing the outside, and a second baffle is disposed on the side of the liquid receiving tray 200 facing the outside. Namely, after the droplet tray 100 and the liquid receiving tray 200 are loaded into the box body 500, the first baffle and the second baffle can block the operation opening, i.e., block external contaminants from entering the box body 500. Further, the first driving member 510 drives the fine adjustment tray to move, and the second driving member 520 drives the liquid receiving tray 200 to move, so that the operation of the droplet generator is more convenient.
In one embodiment, the droplet generating assembly 600 is located inside the box body 500, the droplet generating assembly 600 includes an air pipe 610, a pressure member 620 and a pressure plate 630, the air pipe 610 and the pressure member 620 are connected to the pressure plate 630, and the pressure plate 630 corresponds to the droplet chip 110 on the droplet tray 100. Specifically, the pressurizing member 620 is a cylinder or an oil cylinder. In this embodiment, the pressing member 620 includes a first pressing cylinder and a second pressing cylinder, and the first pressing cylinder and the second pressing cylinder are spaced apart from each other and disposed on the pressing plate 630. The first and second pressing cylinders are used to press the pressing plate 630. Such an embodiment as described above can make the acceptance of the pressing plate 630 more uniform.
As shown in fig. 4 and 5, in one embodiment, a plurality of droplet generating portions are spaced apart from each other on the droplet chip 110, and the droplet holes formed in the droplet tray 100 are in communication with the droplet generating region 111. The droplet generation region 111 includes an oil cavity hole 1111, an air cavity hole 1112 and a droplet generation hole 1113, the droplet generation hole 1113 is communicated with the droplet generation hole, the pressurizing plate 630 is provided with an oil-gas spray nozzle 631 corresponding to the oil cavity hole 1111, and the pressurizing plate 630 is provided with an water-gas spray nozzle 632 corresponding to the air cavity hole 1112; when the oil/gas nozzle 631 is inserted into the oil chamber hole 1111 and the water/gas nozzle 632 is inserted into the gas chamber hole 1112, the droplet generating hole 1113 generates droplets to be discharged through the droplet hole.
Specifically, when the pressure plate 630 presses the droplet chip 110, the oil/gas nozzle 631 contacts with the opening of the oil cavity 1111 and seals the opening completely. And the water vapor spray nozzle 632 is in contact with the opening of the air cavity hole 1112 and seals the opening completely. This embodiment described above prevents leakage of gas after entering the oil chamber hole 1111 or the gas chamber hole 1112. Further, as the gas circulates in the oil chamber hole 1111 and the gas chamber hole 1112, the droplets are collected at the droplet generation hole 1113, and the weight of the collected droplets is continuously increased until the droplets directly drop out through the droplet generation hole and fall into the corresponding pipette 410.
As shown in fig. 4, in one embodiment, the droplet generator further includes a gas supply member 640, a first shunt tube 650 and a second shunt tube 660, the first shunt tube 650 is provided with a first pressure regulating valve 651, the second shunt tube 660 is provided with a second pressure regulating valve 661, one end of the first shunt tube 650 and one end of the second shunt tube 660 are both communicated with the gas pipe 610, the other end of the first shunt tube 650 is communicated with the oil and gas nozzle 631, and the second shunt tube 660 is communicated with the water and gas nozzle 632. Specifically, the gas supply member 640 is a nitrogen cylinder or a syringe pump. The first shunt pipe 650 can be individually controlled by the first pressure regulating valve 651, and the second shunt pipe 660 can be individually controlled by the second pressure regulating valve 661. When the air pressure required in the oil chamber hole 1111 is not the same as the air pressure required in the air chamber hole 1112, the first and second pressure regulating valves 651 and 661 are adjusted.
As shown in fig. 1 and fig. 2, in one embodiment, the droplet generator further includes a third driving member 530, the third driving member 530 is located on the liquid receiving tray 200, the positioning portion 210 includes a slide rail 211, the pipetting member 400 is slidably mounted on the slide rail 211, and the third driving member 530 drives the pipetting member 400 to move along the slide rail 211. The droplet generator further comprises a collecting plate 700, wherein a pre-storing port 710 is formed on the collecting plate 700, and the size of the pre-storing port 710 is consistent with the size of the nozzle of the pipette 410.
Specifically, the third driving member 530 is a motor or a telescopic cylinder, the motor is further provided with a conveyor belt, the conveyor belt is in contact with the pipetting member 400, that is, when the third driving member 530 operates, the conveyor belt can drive the moving member to move along the sliding rail 211, after the dripping operation of the droplet generator is completed, the moving member can be driven by the third driving member 530 to move, that is, to converge toward one end of the droplet generator, then the collection plate 700 extracts the pipettes 410 on the pipetting member 400 through the pre-storage port 710, in this embodiment, a total of 96 microdroplets of 12 × 8 are opened in the droplet generator, corresponding to 12 pipetting members 400, each pipetting member 400 is provided with 8 pipettes 410, when the droplet generator performs droplet generation, the microdroplets are generated simultaneously in 96 microdroplets, when all the pipettes 410 perform droplet generation, the total 96 microdroplets are extracted simultaneously through the third driving member 530 toward one section of the droplet generator, the collection plate 700 is also a total of 96 pipettes of 12 × 8, that is, when all the pipettes 410 are extracted simultaneously, a batch of the pipettes 410 is extracted simultaneously, and a batch of the pipettes 410 can be collected in a batch of 12, and then the pipettes 410 can be collected simultaneously extracted from 96 in the pre-the pipette 410.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only represent some embodiments of the present invention, and the description thereof is specific and detailed, but not to be construed as limiting the scope of the present invention. It should be noted that, for those skilled in the art, without departing from the spirit of the present invention, several variations and modifications can be made, which are within the scope of the present invention. Therefore, the protection scope of the present invention should be subject to the appended claims.
Claims (10)
1. A droplet transfer mechanism, comprising: droplet tray, connect liquid tray, setting element and move liquid piece, the microdroplet has been seted up on the droplet tray, just place the droplet chip that is used for the droplet on the droplet tray, connect the liquid tray with the droplet tray corresponds the setting, just connect be equipped with on the liquid tray with the corresponding positioning portion in microdroplet, move liquid piece and be used for installing the pipette, it movably installs to move liquid piece on the positioning portion, the setting element is used for the mark the corresponding position in microdroplet, move liquid piece edge the setting element removes.
2. The droplet transfer mechanism of claim 1, wherein the droplet tray has a plurality of droplet holes corresponding to the droplet chips, the positioning member is used to mark the positions of the droplet holes, and the droplet transfer members move to the marking positions of the positioning member on the positioning portion in a one-to-one correspondence.
3. A droplet generator comprising the droplet transfer mechanism of claim 1 or 2, further comprising a housing, a droplet generating assembly, and a droplet chip, wherein the droplet transfer mechanism is disposed within the housing, the droplet chip is disposed on the droplet tray, and the droplet generating assembly is mounted in engagement with the droplet chip.
4. A droplet generator according to claim 3, further comprising a first driving member and a second driving member, wherein the droplet tray and the liquid receiving tray are movably disposed in the housing through the operation opening, and the first driving member is connected to the droplet tray and the second driving member is connected to the liquid receiving tray.
5. The apparatus of claim 3, wherein the droplet generating assembly is located inside the housing, the droplet generating assembly comprises a gas pipe, a pressurizing member and a pressurizing plate, the gas pipe and the pressurizing member are both connected to the pressurizing plate, and the pressurizing plate corresponds to the droplet chip on the droplet tray.
6. The droplet generator according to claim 5, wherein a plurality of droplet generating parts are provided at intervals on the droplet chip, and the droplet holes provided in the droplet tray are communicated with the droplet generating regions.
7. The droplet generator according to claim 6, wherein the droplet generating region comprises an oil chamber hole, a gas chamber hole and a droplet generating hole, the droplet generating hole is communicated with the droplet generating hole, the pressure plate is provided with an oil-gas nozzle corresponding to the oil chamber hole, and the pressure plate is provided with a water-gas nozzle corresponding to the gas chamber hole; when the oil gas shower nozzle inserts oil pocket hole, and aqueous vapor shower nozzle inserts when the air pocket hole, the microdroplet generates the hole and produces the microdroplet and passes through the microdroplet hole drips out.
8. The droplet generator according to claim 7, further comprising a gas supply member, a first shunt tube and a second shunt tube, wherein the first shunt tube is provided with a first pressure regulating valve, the second shunt tube is provided with a second pressure regulating valve, one end of the first shunt tube and one end of the second shunt tube are both communicated with the gas pipe, the other end of the first shunt tube is communicated with the oil and gas nozzle, and the second shunt tube is communicated with the water and gas nozzle.
9. The droplet generator of any of claims 3-8, further comprising a third driving member positioned on the receiving tray, wherein the positioning portion comprises a slide track on which the pipetting member is slidably mounted, and wherein the third driving member drives the pipetting member along the slide track.
10. The droplet generator of claim 9, further comprising a collection plate having a pre-stored opening therein, the pre-stored opening having a size corresponding to a size of the orifice of the pipette.
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| CN201921616829.9U CN210875396U (en) | 2019-09-26 | 2019-09-26 | Droplet generator and droplet transfer mechanism |
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| CN201921616829.9U CN210875396U (en) | 2019-09-26 | 2019-09-26 | Droplet generator and droplet transfer mechanism |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114433263A (en) * | 2022-02-08 | 2022-05-06 | 广东永诺医疗科技有限公司 | Liquid-transfering, microdroplet generation and film sealing system |
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2019
- 2019-09-26 CN CN201921616829.9U patent/CN210875396U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114433263A (en) * | 2022-02-08 | 2022-05-06 | 广东永诺医疗科技有限公司 | Liquid-transfering, microdroplet generation and film sealing system |
| CN114433263B (en) * | 2022-02-08 | 2023-09-01 | 广东永诺医疗科技有限公司 | Pipetting, microdroplet generation and film sealing system |
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