CN210869622U - Novel constant-temperature precooling device - Google Patents

Abstract

The utility model discloses a novel constant temperature precooling device, including upper end open-ended box body, the box body is formed by shell and inner shell combination, the airtight space that forms between shell and inner shell is the refrigerant layer, install temperature monitor and rather than the temperature probe of electricity connection on the shell of box body, be provided with the charge door on the shell. The utility model discloses can provide a invariable low temperature environment, effectively solve the damage problem of cryoprotectant to the cell in normal atmospheric temperature operation.

Description

Novel constant-temperature precooling device

Technical Field

The invention relates to the field of biological instruments, in particular to a novel constant-temperature precooling device.

Background

During the sample adding period before cell freezing, the cryoprotectant (such as DMSO) has a large toxic effect on cells at normal temperature, and at 1-8 ℃, the toxic effect is greatly weakened and the cryoprotectant can still permeate into cells at a high speed. The time spent on treating the cells before the cells are frozen is more than half an hour, the environmental temperature for treating the cells is far higher than 1-8 ℃, the toxic and side effects of the cryoprotectant on the cells are larger, and the toxic effect of the cryoprotectant on the cells can be reduced if the cryoprotectant can be operated in the environment of 1-8 ℃.

Disclosure of Invention

The utility model discloses to present problem, a controllable novel constant temperature precooling apparatus of temperature stabilization is provided.

In order to achieve the purpose of the invention, the utility model provides the following technical scheme: the utility model provides a novel constant temperature precooling apparatus, includes upper end open-ended box body, the box body is formed by shell and inner shell combination, the airtight space that forms between shell and inner shell is the refrigerant layer, install temperature monitor and rather than the temperature probe who is connected electrically on the shell of box body, be provided with the charge door on the shell of box body.

The utility model provides a novel constant temperature precooling apparatus, the box body is formed by outer shell and inner shell combination, the airtight space that forms between outer shell and inner shell is the refrigerant layer, add the refrigerant in the refrigerant layer, the refrigerant can be 20% ethylene glycol-water mixed solvent or other ethylene glycol-water mixed solution system of preparing as required, install temperature display and temperature probe on the outer shell, be used for monitoring the temperature of the built-in sample of box body, the charge door that sets up on the outer shell is used for adding the refrigerant, when the temperature that temperature display screen shows the sample was too high, then need to realize the cooling through charge door toward refrigerant layer addition refrigerant, generally need guarantee that the temperature keeps in 1-8 ℃.

As the preferred proposal of the utility model, the box body is in a cuboid shape, and the regular shape is convenient for processing.

As the preferred proposal of the utility model, the inner cavity of the box body is in a rectangular shape and is convenient to process by matching with the appearance of the box body.

As the utility model discloses an optimal scheme, the shell is the double-deck stainless steel construction of taking vacuum heat preservation, reduces box body and external heat exchange, can effectively avoid a large amount of comdenstion water.

As the preferred scheme of the utility model, the inner shell is individual layer stainless steel construction, can transmit temperature.

As the utility model discloses an optimal scheme, be provided with the sample adapter in the box body, it places the hole to be provided with a plurality of cryopreserved pipes on the sample adapter, needs the sample adapter promptly when the operation cryopreserved pipe, and cryopreserved pipe places the hole and is used for placing cryopreserved pipe, and the sample adapter does not have other trompils except placing the hole of cryopreserved pipe, and the impact of the perpendicular wind direction of reducible safety cabinet to the refrigerated air in low temperature district.

As the utility model discloses an optimal scheme, the box body be provided with opening matched with lid, if need low temperature constant temperature preserve after the sample application is accomplished, cover the ambient temperature that the lid can make the interior low temperature zone of box body remain stable.

As the utility model discloses an optimal scheme, the lid is the double-deck stainless steel construction of taking vacuum heat preservation, and the heat preservation effect is better.

As the preferred scheme of the utility model, box body bottom four corners is provided with the stabilizer blade, enables the box body and does not directly place the object contact with desktop etc. and reduce box body and external heat exchange.

Compared with the prior art, the invention has the beneficial effects that: can provide a constant low-temperature environment, and effectively solves the problem that the cryoprotectant damages cells in normal-temperature operation.

Description of the drawings:

fig. 1 is the utility model relates to a novel constant temperature precooling apparatus's box body schematic diagram.

Fig. 2 is the cover schematic diagram of the novel constant temperature precooling apparatus of the present invention.

Fig. 3 is a schematic view of a sample adapter of the novel constant temperature precooling apparatus of the present invention.

Fig. 4 is a bottom view of the box body of the novel constant temperature precooling apparatus.

The labels in the figure are: 1-charging hole, 2-temperature probe, 3-temperature display, 4-outer shell, 5-inner shell, 6-inner cavity, 7-refrigerant layer, 8-adaptive temperature probe end, 9-cover, 10-freezing tube placing hole, 11-sample adapter, 12-box body and 13-foot pad.

Detailed Description

The present invention will be described in further detail with reference to test examples and specific embodiments. It should be understood that the scope of the above-described subject matter is not limited to the following examples, and any techniques implemented based on the disclosure of the present invention are within the scope of the present invention.

All of the features disclosed in this specification, or all of the steps in any method or process so disclosed, may be combined in any combination, except combinations of features and/or steps that are mutually exclusive.

Any feature disclosed in this specification may be replaced by alternative features serving equivalent or similar purposes, unless expressly stated otherwise. That is, unless expressly stated otherwise, each feature is only an example of a generic series of equivalent or similar features.

As shown in fig. 1, 2 and 3, a novel constant temperature precooling device comprises a box body 12 with an open upper end, wherein the box body 12 is formed by combining an outer shell 4 and an inner shell 5, a closed space formed between the outer shell 4 and the inner shell 5 is a refrigerant layer 7, a temperature display 3 and a temperature probe 2 electrically connected with the temperature display 3 are installed on the outer shell 4 of the box body 12, a feed hole 1 is formed in the outer shell 4, the device is used for precooling an ice box at-20 ℃ after a refrigerant is added in advance, and the device is taken out to be used after the temperature is stabilized.

As shown in fig. 1, 2, 3 and 4, the box body 12 is rectangular, the inner cavity 6 of the box body 12 is rectangular, the outer shell 4 is a double-layer stainless steel structure with a vacuum insulation layer, the inner shell 5 is a stainless steel single-layer cavity, the inner shell 5 is a single-layer stainless steel structure, the box body 12 is internally provided with a sample adapter 11, the sample adapter 11 is provided with a plurality of cryopreservation tube placing holes 10, the two optimal sizes of the sample adapter are 25mm in height and 14mm in aperture, the upper part of the cryopreservation tube can still be exposed by about 24mm after being inserted into a 2ml cryopreservation tube, the effective operating distance can be ensured, the added cell suspension can also be ensured under the sample adapter, the second height can be 50mm and the aperture can still be 14mm, thus the sample adapter 14 can be adapted to a 5ml cryopreservation tube, and the sample adapter 14 is placed in the low temperature region 6, the navel blood bag can be directly placed in inner chamber 6 without the sample adapter, box body 12 is provided with lid 9 with opening matched with, lid 9 is the double-deck stainless steel construction of taking vacuum insulation layer, box body 12 bottom four corners is provided with stabilizer blade 13.

Claims (9)

1. The utility model provides a novel constant temperature precooling device which characterized in that: including upper end open-ended box body (12), box body (12) are formed by outer shell (4) and inner shell (5) combination, the airtight space that forms between outer shell (4) and inner shell (5) is refrigerant layer (7), install temperature monitor (3) and rather than temperature probe (2) of electricity connection on outer shell (4) of box body (12), be provided with charge door (1) on outer shell (4).

2. The novel constant-temperature precooling device according to claim 1, wherein: the box body (12) is in a cuboid shape.

3. A novel constant-temperature precooling apparatus as claimed in claim 1 or claim 2, wherein: the inner cavity (6) of the box body (12) is cuboid.

4. A novel constant-temperature precooling apparatus as claimed in claim 1, wherein: the shell (4) is of a double-layer stainless steel structure with a vacuum heat-insulating layer.

5. The novel constant-temperature precooling device according to claim 1, wherein: the inner shell (5) is of a single-layer stainless steel structure.

6. The novel constant-temperature precooling device according to claim 1, wherein: the freezing storage device is characterized in that a sample adapter (11) is arranged in the box body (12), and a plurality of freezing storage tube placing holes (10) are formed in the sample adapter (11).

7. The novel constant-temperature precooling device according to claim 1, wherein: the box body (12) is provided with a cover (9) matched with the opening part.

8. The novel constant-temperature precooling device according to claim 7, wherein: the cover (9) is of a double-layer stainless steel structure with a vacuum heat-insulating layer.

9. The novel constant-temperature precooling device according to claim 1, wherein: and supporting legs (13) are arranged at four corners of the bottom of the box body (12).

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