CN210778482U - Self-suction capillary tube electrospray ion source - Google Patents
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- CN210778482U CN210778482U CN201921992221.6U CN201921992221U CN210778482U CN 210778482 U CN210778482 U CN 210778482U CN 201921992221 U CN201921992221 U CN 201921992221U CN 210778482 U CN210778482 U CN 210778482U
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Abstract
The utility model provides a from inhaling formula capillary electrospray ion source, including advancing the structure, high voltage electrode and high voltage power supply, advance the structure and include stock solution container and hollow capillary, hollow capillary includes main part and top two parts, the entrance of main part is the sample site, insert in the sample solution in the stock solution container, the top of hollow capillary is as spraying end, high voltage power supply exerts high-voltage electricity for sample solution through high voltage electrode, sample solution rises to hollow capillary's top and produces the spraying from hollow capillary's sample site through capillary and electric field force effect, wherein, the internal diameter of hollow capillary main part is 50 microns-500 microns, the internal diameter of spraying end is 20-200 microns, and capillary top internal diameter is not more than the main part internal diameter. The electrospray ion source is favorable for generating a good spraying effect through the hollow capillary tube, liquid drops generated by spraying are fine and easy to dissolve, a complex sample injection structure and a matching device are avoided for ensuring the spraying effect, and the electrospray ion source is simple in structure and convenient to manufacture.
Description
Technical Field
The utility model relates to a mass spectrograph ion source equipment especially relates to a from inhaling formula capillary electrospray ion source.
Background
Mass spectrometers are one of the most sophisticated modern analytical instruments and represent the direction of future development of analytical instruments. The ion source is the most basic functional component in a mass spectrometer system, and determines the analysis performance and the application range of the mass spectrometer to a certain extent. Electrospray Ionization (ESI) was originally an Ionization technique proposed by Dole group and applied to mass spectrometry, and was first applied to the detection of protein molecules by the late 80 s of the last century by nobel prize-taker John b. ESI has become the most widely used ion source in mass spectrometry today, and its application range also extends from the field of biomacromolecules to inorganic and organic micromolecules, which also opens up a new era of modern mass spectrometry.
As disclosed in chinese patent publication No. CN 103545166A: the basic structure of an ESI ion source is to introduce a sample solution into a hollow capillary using a sample injection device, and apply a high voltage to the capillary or solution to form an electrospray, generating ions at atmospheric pressure. Most of the existing electrospray ion sources need an injection pump to push a sample solution into a capillary, or need to form a certain pressure difference at an inlet and an outlet of the capillary to drive liquid, so that a complex sample introduction structure and a matching device need to be configured, which is not beneficial to simplifying the structure of an instrument
The inventor researches and designs a hollow capillary electrospray ion source, and finds that liquid can be driven to move in a capillary by the capillary action of the hollow capillary, and spray can be generated by applying high pressure. However, the inner and outer diameters of the capillary and the electric field force affect the effect of the spray, not all the capillaries can form effective electrospray, and the spraying effects of the capillaries with different inner and outer diameters and different tube wall thicknesses are very different, so that if the hollow capillary is not properly selected, the normal use of the electrospray ion source is affected. In some cases, even if the applied voltage is higher, the spray cannot be generated by simply relying on the capillary action of the capillary itself; in some cases, the spray generated by the capillary tube cannot form a single taylor cone, and multiple sprays occur simultaneously, which affects the electrospray effect. In this case, it is often necessary to ensure the formation of an effective electrospray by means of complex auxiliary structures, for example by generating a greater pressure difference, and by adding a sheath gas, etc.
SUMMERY OF THE UTILITY MODEL
The utility model discloses a main aim at overcomes prior art not enough, provides a from inhaling formula capillary electrospray ion source to under the condition that need not be with the help of complicated auxiliary structure, rely on cavity capillary self and electric field force to guarantee good spraying effect.
In order to achieve the above purpose, the utility model adopts the following technical scheme:
a self-suction capillary electrospray ion source comprises a high-voltage power supply, a high-voltage electrode and a sample introduction structure, wherein the high-voltage electrode is used for electrifying a sample solution to be detected in a sample container; the sample introduction structure comprises a liquid storage container and a hollow capillary tube, the liquid storage container is used for containing sample solution, the hollow capillary tube comprises a main body and a top end, an inlet of the main body is inserted into the sample solution to serve as a sampling end, and the top end of the hollow capillary tube serves as a spraying end; the high-voltage power supply is applied to the high-voltage electrode and is used for providing high voltage required by electrospray; the sample solution rises from the sampling end of the hollow capillary to the top end of the hollow capillary by capillary action and electric field force action and generates spray, wherein the inner diameter of the main body of the hollow capillary is within the range of 50-500 microns, the inner diameter of the top end of the hollow capillary is within the range of 20-200 microns, and the inner diameter of the top end of the capillary is not more than the inner diameter of the main body.
Further, the top end of the hollow capillary tube is a straight opening, an inclined opening or a conical opening.
Further, the wall thickness of the hollow capillary tip is no greater than 300 microns.
Furthermore, the end face of the spraying end is flat and burr-free.
Furthermore, the inner cavity of the spraying end of the hollow capillary tube is a reducing inner cavity and an equal-diameter inner cavity
Further, the high-voltage power supply is high-voltage direct current or alternating current.
Further, the high voltage electrode is electrically connected to the sample solution in a contact or non-contact manner, i.e. the high voltage may be applied to the sample solution, or to the outer wall of the hollow capillary, or to the reservoir, or to a distance around the surface of the sample solution.
Furthermore, the self-suction capillary electrospray ion source also comprises a sample injection structure fixing device and a sample injection structure adjusting device, wherein the sample injection structure fixing device comprises a capillary and a high-voltage electrode fixing frame, and the high-voltage electrode is inserted into the liquid storage container; advance a kind structure adjusting device and include liquid storage container position control and fixing device and cavity capillary spraying end position adjusting device, liquid storage container position control is used for fixing with fixing device liquid storage container can adjust the liquid storage container position, cavity capillary spraying end position adjusting device is used for adjusting the direction of spraying end, makes produced spraying can get into the mass spectrograph more effectively.
Further, the sample feeding structure is arranged in the atmosphere, or in a vacuum cavity with vacuum degree, or in a heatable cavity, or in the heatable cavity with vacuum degree.
Compared with the prior art, the method has the beneficial effects that:
the inventor researches and designs a hollow capillary tube electrospray ion source, and finds that under the condition that the capillary tube and the electric field force jointly influence the spray generation effect, not all the capillary tubes with capillary action can form effective electrospray, the spray effects of the capillary tubes with different inner diameters, outer diameters and spray end shapes are greatly different, if the inner diameters of the capillary tubes are large to a certain degree, the liquid level cannot climb to a sufficient height through the capillary action and the electric field force, and if the inner diameters of the capillary tubes are too small, the solution supply speed cannot keep up with the solution supply speed after spraying, and continuous spray cannot be formed. The inventor finds that when the inner diameter of the hollow capillary main body is 50-500 micrometers, the inner diameter of the spraying end of the hollow capillary is 20-200 micrometers, and the inner diameter of the top end of the capillary is not larger than the inner diameter of the main body, a solution can smoothly reach the spraying end under the combined action of capillary action and electric field force, so that the electrospray ion source generates high-quality continuous electrospray, droplets generated by the spray are fine, and the droplets are easy to dissolve. And the capillary top internal diameter is not more than the main part internal diameter can guarantee to obtain the taylor awl spraying effect of preferred, avoids appearing a plurality of spraying phenomena in the spraying end, is favorable to implementing ESI mass spectrum sampling high-efficiently steadily, and the voltage that produces the electrospray is less relatively, only needs the voltage about 1500 volts just can produce the spraying, and then has reduced the consumption of instrument.
Because the good spraying effect can be ensured by depending on the hollow capillary tube and the electric field force, the electric spraying ion source of the utility model can also avoid the adoption of a complex sample feeding structure and a matching device in the past for ensuring the obtaining of the spraying effect, avoid the phenomenon of cross contamination among samples, is easy to clean and reduces the consumption of the samples; the requirement for the ion source sample for generating the spray is less, and the nano-liter level can be achieved; the preparation is simple, the cost is low, a complex processing process is not needed, and the material is convenient to be used as a consumable material; the complex sample introduction structure is omitted, so that the replacement of the capillary tube is convenient; the ion source device has the advantages of simplifying the structure, reducing the volume of the ion source device and being suitable for being used with various mass spectrometers including a large mass spectrometer and a portable small mass spectrometer.
In a preferred embodiment, the spraying end of the hollow capillary is designed as a tip, and the hollow capillary can further improve the spraying effect.
In a preferred embodiment, the wall thickness of the spray end of the hollow capillary is no greater than 300 microns. The inventor also finds that the different tube wall thicknesses and different surface flatness degrees of the spraying end of the hollow capillary tube have great influence on the spraying effect, when the tube wall of the spraying end capillary tube is thick, particularly the tube wall thickness exceeds 300 micrometers, the processing quality of the end surface of the spraying end is difficult to ensure, burrs are easy to generate, the hollow capillary tube easily generates spraying at the burrs, so that a single taylor cone is difficult to obtain, the phenomenon of multiple spraying is often caused, the electric spraying effect is influenced, the surface flatness degree is difficult to ensure, burrs are easy to generate during processing, at the moment, the spraying generated by the hollow capillary tube is difficult to obtain the single taylor cone, the spraying is often caused at the burrs, the phenomenon of multiple spraying is further generated, the electric spraying effect is influenced, therefore, the utility model discloses a preferable scheme sets the wall thickness of the hollow capillary tube not more than 300 micrometers, the processing quality of the spraying end can be effectively guaranteed, the phenomenon of multiple sprays is avoided, and the sprays are kept to be single Taylor cones. In a further preferred scheme, the wall thickness of the spraying end of the hollow capillary tube is set to be not more than 300 microns, the end face of the spraying end is flat and free of burrs, a better Taylor cone spraying effect can be obtained, and mass spectrum sampling can be efficiently and stably implemented.
In addition, the embodiment of the present invention can also obtain other advantages, for example, the position adjustment of the sample injection structure can be implemented through the sample injection structure adjusting device; the ion source sampling structure can also be set to work in the vacuum cavity and the heating cavity, and is favorable for further improving the spraying effect and the desolventizing effect.
Drawings
Fig. 1 is a schematic structural diagram of a self-priming capillary electrospray ion source according to an embodiment of the present invention;
fig. 2 is a schematic view of several hollow capillaries in an embodiment of the present invention, wherein the enlarged portion is a schematic view of the top end of the hollow capillary;
FIG. 3 is a schematic view of a sample injection structure according to an embodiment of the present invention;
fig. 4 is a schematic structural diagram of a self-priming capillary electrospray ion source according to another embodiment of the present invention.
Detailed Description
The embodiments of the present invention will be described in detail below. It should be emphasized that the following description is merely exemplary in nature and is not intended to limit the scope of the invention or its application.
It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or be indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or be indirectly connected to the other element. The connection may be for fixation or for circuit connection.
It is to be understood that the terms "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like are used in the orientation or positional relationship indicated in the drawings for convenience in describing the embodiments of the present invention and to simplify the description, and are not intended to indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and are not to be construed as limiting the invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the embodiments of the present invention, "a plurality" means two or more unless specifically limited otherwise.
Referring to fig. 1 and 4, in one embodiment, a self-priming capillary electrospray ion source comprises a high voltage power supply 6, a high voltage electrode 5 and a sample injection structure 9, the sample feeding structure 9 comprises a liquid storage container 3 and a hollow capillary 2, the liquid storage container 3 is used for containing a sample solution 4, the sampling end of the hollow capillary 2 is inserted into the sample solution 4 in the liquid storage container 3 to be used as a sample introduction end, the top end of the hollow capillary 2 is used as a spraying end, the high-voltage power supply 6 is applied to the sample solution 4 through a high-voltage electrode 5, for providing high voltage required for electrospray, the sample solution 4 rises from the sampling end of the hollow capillary 2 to the top end of the hollow capillary 2 by capillary action and electric field force, to generate a spray 7 at the tip of the hollow capillary 2, the electricity applied by the high voltage power supply 6 to the high voltage electrode 5 may be either a high voltage direct current or a high voltage alternating current.
When studying and designing an electrospray ion source with a hollow capillary tube, the inventor finds that under the condition that the capillary tube and the electric field force jointly influence the spray generation effect, all the capillary tubes with the capillary action can not form effective electrospray, and the spray effects of the capillary tubes with different inner diameters, outer diameters and spray end shapes are greatly different. The inventor finds that through a great deal of research, the inner diameter of the hollow capillary tube main body is 50-500 microns, the inner diameter of the spraying end of the hollow capillary tube is 20-200 microns, the inner diameter of the top end of the capillary tube is not larger than the inner diameter of the main body, a solution can smoothly reach the spraying end under the combined action of capillary action and electric field force, so that the electrospray ion source generates high-quality continuous electrospray, droplets generated by the spray are fine and easy to dissolve, a better Taylor cone spray effect can be obtained, multiple spray phenomena are avoided, ESI mass spectrum sampling can be efficiently and stably performed, the voltage required for generating the electrospray is relatively small, the spray can be generated by only about 1500 volts, and when the inner diameters of the hollow capillary tube and the spraying end are in the range, the spray effect can be improved by increasing the voltage, the voltage is higher, the better the spraying effect. In contrast, when the inner diameter of the hollow capillary tube main body part is larger, the sample solution is difficult to rise to the spraying end to form a spraying effect under the combined action and influence of the self gravity, the capillary action of the capillary tube and the electric field force of the liquid, and when the hollow capillary tube main body adopts a smaller inner diameter (for example, smaller than 50 micrometers), although the capillary action is strong, the rising volume of the solution is too small, the subsequent solution cannot be supplemented in time after the spraying is formed, and therefore continuous spraying cannot be generated.
In a preferred embodiment, the spray end of the hollow capillary 2 is also shaped as a bevel, a constant inner diameter taper, and a variable inner diameter taper (see fig. 2). Through the optimal design, the shape of the spraying end of the hollow capillary tube is provided with an inclined opening, a taper opening with invariable inner diameter and a taper opening with variable inner diameter, and the hollow capillary tube can further improve the spraying effect.
In a preferred embodiment, the hollow capillary 2 is provided with a wall thickness of no more than 300 microns. The inventor has also found through the research that the different tube wall thickness of cavity capillary spraying end and different terminal surface roughness are very big to the influence difference of spraying effect, and when spraying end capillary wall was thick, especially the tube wall thickness exceeded 300 microns, hardly guaranteed the processingquality of spraying end terminal surface, produce the burr easily, the cavity capillary is in the easy spraying that produces of burr department, therefore difficult single taylor awl that obtains, often leads to the phenomenon of taking place a plurality of spraying, influences the electric spray effect, to this, the utility model discloses set the wall thickness of cavity capillary spraying end to be not more than 300 microns in the preferred scheme, can avoid taking place the phenomenon of a plurality of spraying effectively, make the spraying keep single taylor awl.
In a further preferred scheme, the wall thickness of the spraying end of the hollow capillary tube 2 is set to be not more than 300 microns, the end face of the spraying end is flat and free of burrs, a better Taylor cone spraying effect can be obtained, and mass spectrum sampling can be efficiently and stably carried out.
In various embodiments, the high voltage power supply 6 applies high voltage to the sample solution 4 through the high voltage electrode 5, and the high voltage power supply may be in a contact type or a non-contact type. In some embodiments, the high voltage power source 6 may apply high voltage to the sample solution 4 in the reservoir 3, as shown in fig. 1-3; in other embodiments, a high voltage may be applied to the outer wall of the hollow capillary 2, to the bottom end of the reservoir 3, or to the periphery of the liquid level of the sample solution 4, such as a distance above the liquid level.
In a preferred embodiment, the spray end of the hollow capillary tube 2 is formed as a tip (e.g., fig. 2). The tip can be formed by a method of fire wire drawing or a method of chemical corrosion for the glass capillary.
In a preferred embodiment, as shown in fig. 4, the self-priming capillary electrospray ion source further comprises a sample injection structure fixing device 9 and a sample injection structure position adjusting device 10, the sample injection structure fixing device is used for fixing the hollow capillary 2, the high-voltage electrode 5 connected with the high-voltage power supply 6 and the liquid storage container 3, the high-voltage electrode 5 is inserted into the liquid storage container 3, the sample injection structure adjusting device 10 comprises a liquid storage container position adjusting and fixing device and a hollow capillary tube spraying end position adjusting device, the liquid storage container position adjusting and fixing device is used for fixing the liquid storage container 3 and adjusting the position of the liquid storage container 3, the hollow capillary tube spray end position adjusting device is used for adjusting the direction of the spray end of the hollow capillary tube 2, so that the generated spray can enter the mass spectrometer more effectively.
In some embodiments, the sample introduction structure of the electrospray ion source may be disposed in an atmospheric pressure environment. In a preferred embodiment, the sample introduction structure may be disposed in a vacuum chamber having a certain vacuum degree. In another preferred embodiment, the sample introduction structure may be disposed within a heatable cavity. In another preferred embodiment, the sample feeding structure can also be arranged in a heatable cavity with a certain vacuum degree.
The utility model discloses an electrospray ion source does not receive the influence of space and environment, both can work under atmospheric pressure, also can put its whole vacuum cavity work that has certain vacuum, can also improve the spraying effect at inclosed cavity work that can heat.
The utility model discloses an electrospray ion source structure is simplified, and convenient to use can jointly use with big mass spectrum or portable little mass spectrum.
The following describes the self-priming capillary electrospray ion source and the related manufacturing process according to the exemplary embodiment of the present invention with reference to the drawings.
As shown in fig. 3 and 4, an exemplary self-priming capillary electrospray ion source comprises a sample feeding structure, the sample feeding structure comprises a high voltage electrode 5, a hollow capillary 2, a bracket 8 and a liquid storage container 3, the liquid storage container 3 is used for containing a sample solution, a sampling end of the hollow capillary 2 is inserted into the sample solution in the liquid storage container 3 as a sample feeding end, a top end of the hollow capillary 2 is used as a spraying end, and the high voltage electrode 5 applies a high voltage to the sample solution in the liquid storage container. The liquid storage container 3 adopts a centrifugal tube. The sample injection structure is also provided with a high-voltage electrode fixing frame sample injection structure position adjusting device 10 matched with the sample injection structure. The spraying end of the hollow capillary 2 is matched with the sample inlet 1 of the mass spectrometer.
The inner diameter of the hollow capillary tube main body is 50-500 micrometers, the inner diameter of the spraying end of the hollow capillary tube 2 is set to be 20-200 micrometers, the wall thickness of the spraying end of the hollow capillary tube 2 is set to be not more than 300 micrometers, the inner diameter of the main body of the central control capillary tube is less than or equal to the inner diameter of the top end of the capillary tube, and the end face of the spraying end of the hollow capillary tube 2 is flat and free of burrs. When the ionization type sample solution sampling device works, the sampling end of the hollow capillary tube 2 is inserted into a solution in the liquid storage container 3, meanwhile, high-voltage electricity is applied to the solution (contact type high-voltage electricity), or the outer wall of the capillary tube, or the periphery of the liquid level of the solution (non-contact type high-voltage electricity), the sample solution quickly rises to the top end of the hollow capillary tube through the action of capillary and electric field force, and spray is generated at the top end of the hollow capillary tube, so that the ionization effect is achieved. Moreover, the voltage required by the hollow capillary tube 2 for generating the electrospray is relatively small, the spray can be generated only by about 1500V, a better Taylor cone spray effect can be obtained, and the ESI mass spectrum sampling can be efficiently and stably implemented. The ion source device does not need high voltage, does not need sheath gas, and does not need to ensure the condition that the hollow capillary tube generates the spray by means of external assistance (such as a device for increasing pressure difference and a mechanical sample introduction device) through a complex structure.
The spraying end of the hollow capillary 2 is preferably formed as a tip, which can improve its spraying effect. During manufacture, the middle position of the capillary tube can be burnt by using outer flame of flame, and the two ends of the capillary tube are pulled outwards by using uniform force until the capillary tube is broken. The method for forming the tip by the capillary spray tip can be sand sanding, laser cutting and the like. In addition, the spray end of the capillary tube can be fired after laser cutting, or can be directly processed by a ceramic blade.
The ion source sampling structure is arranged in a vacuum cavity with vacuum degree, and the working environment is in low vacuum, so that the influence of gas impurities in the atmosphere on the spraying effect and the ionization effect can be favorably removed. The working environment of the ion source sampling structure can be in the heating cavity, and the heating cavity is used for heating, so that the generated spray can be accelerated to remove the solvent, and the spray ionization efficiency is improved. Of course, it is also preferable that the chamber used has both the functions of low vacuum and heating the chamber.
The non-contact electrification of the solution is arranged, for example, on the outer wall of the quartz capillary or around the liquid level outside the solution, so that pollution caused by a conductive structure can be effectively avoided, and cross pollution among samples can be better avoided when the capillary is replaced.
The foregoing is a more detailed description of the present invention, taken in conjunction with the specific/preferred embodiments thereof, and it is not intended that the invention be limited to the specific embodiments shown and described. For those skilled in the art to which the invention pertains, a plurality of alternatives or modifications can be made to the described embodiments without departing from the concept of the invention, and these alternatives or modifications should be considered as belonging to the protection scope of the invention. In the description herein, references to the description of the term "one embodiment," "some embodiments," "preferred embodiments," "an example," "a specific example," or "some examples" or the like, mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, the schematic representations of the terms used above are not necessarily intended to refer to the same embodiment or example. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples. Furthermore, various embodiments or examples and features of different embodiments or examples described in this specification can be combined and combined by one skilled in the art without contradiction.
Claims (9)
1. A self-suction capillary electrospray ion source is characterized by comprising a high-voltage power supply, a high-voltage electrode and a sample introduction structure, wherein the high-voltage electrode is used for electrifying a sample solution to be detected in a sample container; the sample introduction structure comprises a liquid storage container and a hollow capillary tube, the liquid storage container is used for containing sample solution, the hollow capillary tube comprises a main body and a top end, an inlet of the main body is inserted into the sample solution to serve as a sampling end, and the top end of the hollow capillary tube serves as a spraying end; the high-voltage power supply is applied to the high-voltage electrode and is used for providing high voltage required by electrospray; the sample solution rises from the sampling end of the hollow capillary to the top end of the hollow capillary by capillary action and electric field force action and generates spray, wherein the inner diameter of the main body of the hollow capillary is within the range of 50-500 microns, the inner diameter of the top end of the hollow capillary is within the range of 20-200 microns, and the inner diameter of the top end of the capillary is not more than the inner diameter of the main body.
2. The self-priming capillary electrospray ion source according to claim 1, wherein the top end of the hollow capillary is straight, angled or tapered.
3. The self-priming capillary electrospray ion source according to any of claims 1 or 2, wherein the wall thickness of the tip of said hollow capillary is not greater than 300 μm.
4. The self-priming capillary electrospray ion source according to claim 3, wherein the end face of the spray end of the hollow capillary is flat and burr-free.
5. The self-priming capillary electrospray ion source according to any of claims 1 or 2, wherein the inner cavity of the spray end of the hollow capillary is a variable diameter inner cavity and a constant diameter inner cavity.
6. The self-priming capillary electrospray ion source according to any of claims 1 or 2, wherein the high voltage power supply is either high voltage direct current or high voltage alternating current.
7. The self-priming capillary electrospray ion source according to any of claims 1 or 2, wherein the high voltage electrode energizes the sample solution in a contact or non-contact manner, i.e. the high voltage is applied within the sample solution, or on the outer wall of the hollow capillary, or on the reservoir, or at a distance around the liquid level of the sample solution.
8. The self-priming capillary electrospray ion source according to any of claims 1 and 2, further comprising a sample introduction structure fixing device and a sample introduction structure adjusting device, wherein the sample introduction structure fixing device comprises a capillary and a high voltage electrode fixing frame, and the high voltage electrode is inserted into the liquid storage container; advance a kind structure adjusting device and include liquid storage container position control and fixing device and cavity capillary spraying end position adjusting device, liquid storage container position control is used for fixing with fixing device liquid storage container can adjust the liquid storage container position, cavity capillary spraying end position adjusting device is used for adjusting the direction of spraying end.
9. The self-priming capillary electrospray ion source according to any of claims 1 or 2, wherein the sample introduction structure is disposed in an atmospheric pressure environment, or in a vacuum chamber having a vacuum degree, or in a heatable chamber having a vacuum degree.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113390949A (en) * | 2021-08-17 | 2021-09-14 | 深圳至秦仪器有限公司 | On-site portable ion trap mass spectrometry detection method for carbendazim in fruits and vegetables |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113390949A (en) * | 2021-08-17 | 2021-09-14 | 深圳至秦仪器有限公司 | On-site portable ion trap mass spectrometry detection method for carbendazim in fruits and vegetables |
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