CN210750947U - Focused ultrasound scientific research platform - Google Patents

Focused ultrasound scientific research platform Download PDF

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Publication number
CN210750947U
CN210750947U CN201920350726.6U CN201920350726U CN210750947U CN 210750947 U CN210750947 U CN 210750947U CN 201920350726 U CN201920350726 U CN 201920350726U CN 210750947 U CN210750947 U CN 210750947U
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focused ultrasound
transducer
input end
output end
matching circuit
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CN201920350726.6U
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黄汉年
汪昌明
吴敏慧
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Shenzhen Biomedical Research Institute
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Shenzhen Biomedical Research Institute
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Abstract

The utility model discloses a relate to high strength focus supersound technical field, include: focused ultrasound equipment, experiment operation panel and display device, focused ultrasound equipment is used for producing the high strength focus ultrasonic wave, the experiment operation panel is used for fixed test object, display device is arranged in catching the image information of experimentation to projection display through combining focused ultrasound equipment, experiment operation panel and display device, provides an ultrasonic scientific research platform that low cost, function are complete and are applicable to the teaching.

Description

Focused ultrasound scientific research platform
Technical Field
The utility model belongs to the technical field of the focused ultrasound technique that excels in and specifically relates to a focused ultrasound scientific research platform.
Background
HIFU, High Intensity Focused Ultrasound (HIFU), refers to focusing low-energy ultrasonic waves in vitro on a target area in vivo by using ultrasonic waves, and generating biological effects such as transient High temperature, cavitation, mechanical action and the like in a tumor to kill tumor cells in the target area.
In order to enable the HIFU technology to act on a tumor treatment mechanism, a plurality of basic experimental researches and verifications are required in the process, the existing HIFU treatment equipment and scientific research equipment are mutually independent, and the simple HIFU treatment equipment has higher cost and cannot be better applied to scientific research and teaching tasks aiming at human body treatment.
SUMMERY OF THE UTILITY MODEL
The present invention aims at solving at least one of the technical problems in the related art to a certain extent. Therefore, the utility model aims at providing a focus supersound scientific research platform of scientific research and teaching is used in the adaptation.
The utility model adopts the technical proposal that:
the utility model provides a focus supersound scientific research platform, include: the device comprises a focused ultrasound device, an experiment operating platform and a display device, wherein the focused ultrasound device is used for generating high-intensity focused ultrasonic waves, the experiment operating platform is used for fixing a test object, and the display device is used for capturing image information in an experiment process and performing projection display.
Further, the focused ultrasound device comprises: host computer, power source, transducer unit, positioning system and three-dimensional motion control platform, the output of host computer is connected respectively the input of power source with the input of three-dimensional motion control platform, the transducer unit assemble in on the three-dimensional motion control platform, the output of power source is connected the input of transducer unit, positioning system is used for gathering the image information of experimentation and transmits for the host computer to the monitoring experimentation.
Further, the focused ultrasound device further comprises an auxiliary system, wherein the auxiliary system is used for preparing medium water, and the transducer unit comprises a transducer module which is placed in the medium water.
Further, the power source comprises a signal source, a first-stage power amplifier module and a second-stage power amplifier module, the input end of the signal source is connected with the output end of the upper computer, the output end of the signal source is connected with the input end of the first-stage power amplifier module, the output end of the first-stage power amplifier module is connected with the input end of the second-stage power amplifier module, and the output end of the second-stage power amplifier module is connected with the input end of the energy converter unit.
Further, the transducer unit includes: the transducer unit includes: the ultrasonic ablation device comprises an HIFU thermal ablation transducer and/or an ultrasonic cavitation transducer, a wiring terminal, a first matching circuit and/or a second matching circuit, wherein the input end of the wiring terminal is connected with the output end of the power source, the output end of the wiring terminal is connected with the input end of the first matching circuit and/or the input end of the second matching circuit, the output end of the first matching circuit is connected with the input end of the HIFU thermal ablation transducer, and the output end of the second matching circuit is connected with the input end of the ultrasonic cavitation transducer.
Furthermore, the positioning system comprises a B ultrasonic instrument or a magnetic resonance imager, and the output control parameters of the upper computer and the transducer unit are adjusted through the imaging result of the B ultrasonic instrument or the magnetic resonance imager.
Further, display device includes high-speed camera and projecting apparatus, high-speed camera with the projecting apparatus frame is located respectively on the experiment operation panel, high-speed camera is used for gathering the image information in the experimentation, the projecting apparatus is used for enlargeing gather the image information in the experimentation.
Furthermore, the focused ultrasound device further comprises a direct current stabilized voltage power supply, wherein the output end of the direct current stabilized voltage power supply is connected with the input end of the power source, and the voltage of the direct current stabilized voltage power supply is adjustable.
The utility model has the advantages that:
the utility model discloses a focus supersound scientific research platform, include: the focused ultrasound equipment, the experiment operating table and the display device are organically combined, so that the ultrasonic scientific research platform which is low in cost, complete in function and suitable for teaching is provided.
Drawings
Fig. 1 is a schematic structural diagram of a specific embodiment of a focused ultrasound research platform according to the present invention;
fig. 2 is a schematic structural diagram of a specific embodiment of a focused ultrasound device in a focused ultrasound research platform according to the present invention;
FIG. 3 is a schematic structural diagram of an embodiment of a transducer unit in a focused ultrasound research platform according to the present invention;
fig. 4 is a schematic structural diagram of a specific embodiment of a power source in a focused ultrasound research platform according to the present invention.
Detailed Description
It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict.
As shown in fig. 1, fig. 1 is a block diagram of a specific embodiment of a focused ultrasound research platform of the present invention, which includes: the device comprises a focused ultrasound device, an experiment operating platform and a display device, wherein the focused ultrasound device is used for generating high-intensity focused ultrasonic waves, the experiment operating platform is used for fixing a test object, and the display device is used for capturing image information in an experiment process and performing projection display. The output end of the generating device of the focused ultrasound equipment is erected above the experiment operating platform, and the experiment operating platform is connected with the display device.
Focused ultrasound equipment is used for fixing a position and destroying focus tissue, and the experiment operation panel is including pressing from both sides animal experiment anchor clamps for restraint animal action or fixed separation tissue go on smoothly in order to ensure the ultrasonic experiment, display device are used for supplementary teaching and demonstration, and is concrete, display device include high-speed camera and projecting apparatus, high-speed camera with the projecting apparatus frame is located respectively on the experiment operation panel, high-speed camera is used for gathering the image information of experimentation, the projecting apparatus is used for enlargeing gather the image information of experimentation.
The ultrasonic scientific research platform which is low in cost, complete in function and suitable for teaching is provided by organically combining the focused ultrasonic equipment, the experiment operating platform and the display device.
Specifically, as shown in fig. 2, fig. 2 is the embodiment of the utility model provides an in the embodiment of a structural schematic diagram of focused ultrasound equipment among focused ultrasound scientific research platform, focused ultrasound equipment includes: host computer, power source, transducer unit, positioning system and three-dimensional motion control platform, the output of host computer is connected respectively the input of power source with the input of three-dimensional motion control platform, the transducer unit assemble in on the three-dimensional motion control platform, the output of power source is connected the input of transducer unit, positioning system is used for gathering the image information of experimentation and transmits for the host computer to the monitoring experimentation.
The upper computer is used for outputting the treatment planning experiment scheme and sending the striking parameters to the power source through the serial port.
The power source receives the treatment parameters received by the upper computer, generates an excitation signal and outputs the excitation signal to the transducer unit, and the transducer unit generates high-intensity focused ultrasound.
The direct current stabilized power supply is used for providing voltage under the corresponding treatment mode for the power source.
The transducer unit is assembled on the three-dimensional motion control platform, the upper computer drives the transducer unit to realize accurate positioning through the three-dimensional motion control platform, and the transducer unit and the three-dimensional motion control platform are assembled and can be disassembled.
The auxiliary system is a medium water preparation device and is used for providing steam removal water, automatic water pumping and self-service drainage, the energy converter unit comprises an energy converter module, the energy converter module is arranged in the medium water, an ultrasonic transmission channel is optimized through the medium water, and energy loss is reduced.
The positioning system is used for detecting the dynamic focusing information and feeding back the dynamic focusing information to the upper computer. Specifically, the positioning system comprises a B ultrasonic instrument or a magnetic resonance imager, and output control parameters of the upper computer and the transducer unit are adjusted through an imaging result of the B ultrasonic instrument or the magnetic resonance imager.
As shown in fig. 3, the transducer unit in this embodiment includes: the ultrasonic ablation device comprises an HIFU thermal ablation transducer and/or an ultrasonic cavitation transducer, a wiring terminal, a first matching circuit and/or a second matching circuit, wherein the input end of the wiring terminal is connected with the output end of the power source, the output end of the wiring terminal is connected with the input end of the first matching circuit and/or the input end of the second matching circuit, the output end of the first matching circuit is connected with the input end of the HIFU thermal ablation transducer, and the output end of the second matching circuit is connected with the input end of the ultrasonic cavitation transducer.
The power source supports an HIFU thermal ablation mode and an ultrasonic cavitation mode, and the HIFU thermal ablation mode enables the biological focus tissues to generate coagulation necrosis through the thermal effect generated by the transducer; the ultrasonic cavitation mode leads the interior of the biological focus tissue to burst through the cavitation effect generated by the transducer, and homogenate is formed.
Under the HIFU thermal ablation mode, a DC voltage stabilizing source outputs 40-100V voltage, a large-current signal output by a power source forms a stable sine wave after passing through a wiring terminal and a matching circuit, the sine wave is loaded at two ends of an HIFU thermal ablation transducer, so that the ultrasonic transducer generates high-intensity ultrasonic waves, the ultrasonic waves penetrate through a coupling layer, enter normal tissues and are focused in focus tissues to form an ellipsoidal focal zone, the temperature in the focal zone is rapidly raised to be more than 65 ℃, irreversible coagulation necrosis of the tissues in the focal zone is caused, and the treatment purpose is achieved.
Under an ultrasonic cavitation mode, a direct-current voltage stabilizing source outputs 150-250V voltage, a large-current signal output by a power source forms stable pulse waves after passing through a wiring terminal and a matching circuit, the pulse waves are loaded on an ultrasonic cavitation transducer to generate high-intensity ultrasonic waves, the ultrasonic waves penetrate through a coupling layer to enter normal tissues and focus in focus tissues to form an ellipsoidal focal region, and the sound pressure in the focal region rapidly reaches an air threshold value to enable histiocytes to undergo a compression expansion process until finally bursting to form tissue homogenate.
As shown in fig. 4, the power source includes a signal source, a first power amplifier module and a second power amplifier module, the input end of the signal source is connected to the output end of the upper computer, the output end of the signal source is connected to the input end of the first power amplifier, the output end of the first power amplifier is connected to the input end of the second power amplifier, and the output end of the second power amplifier is connected to the input end of the transducer.
Only the modules necessary for scientific research and teaching of the focused ultrasound equipment are reserved, and the equipment cost can be obviously reduced.
While the preferred embodiments of the present invention have been described, the present invention is not limited to the embodiments, and those skilled in the art can make various equivalent modifications or substitutions without departing from the spirit of the present invention, and such equivalent modifications or substitutions are intended to be included within the scope of the present invention as defined by the appended claims.

Claims (8)

1. A focused ultrasound research platform, comprising: the device comprises a focused ultrasound device, an experiment operating platform and a display device, wherein the focused ultrasound device is used for generating high-intensity focused ultrasonic waves, the experiment operating platform is used for fixing a test object, and the display device is used for capturing image information in an experiment process and performing projection display.
2. The focused ultrasound research platform according to claim 1, wherein the focused ultrasound device comprises: host computer, power source, transducer unit, positioning system and three-dimensional motion control platform, the output of host computer is connected respectively the input of power source with the input of three-dimensional motion control platform, the transducer unit assemble in on the three-dimensional motion control platform, the output of power source is connected the input of transducer unit, positioning system is used for gathering the image information of experimentation and transmits for the host computer to the monitoring experimentation.
3. The focused ultrasound research platform according to claim 2, wherein the focused ultrasound equipment further comprises an auxiliary system for producing medium water, and the transducer unit comprises a transducer module disposed in the medium water.
4. The focused ultrasound scientific research platform according to claim 2, wherein the power source comprises a signal source, a first-stage power amplifier module and a second-stage power amplifier module, the input end of the signal source is connected with the output end of the upper computer, the output end of the signal source is connected with the input end of the first-stage power amplifier module, the output end of the first-stage power amplifier module is connected with the input end of the second-stage power amplifier module, and the output end of the second-stage power amplifier module is connected with the input end of the transducer unit.
5. The focused ultrasound research platform of claim 2, wherein the transducer unit comprises: the ultrasonic ablation device comprises an HIFU thermal ablation transducer and/or an ultrasonic cavitation transducer, a wiring terminal, a first matching circuit and/or a second matching circuit, wherein the input end of the wiring terminal is connected with the output end of the power source, the output end of the wiring terminal is connected with the input end of the first matching circuit and/or the input end of the second matching circuit, the output end of the first matching circuit is connected with the input end of the HIFU thermal ablation transducer, and the output end of the second matching circuit is connected with the input end of the ultrasonic cavitation transducer.
6. The focused ultrasound research platform according to claim 2, wherein the positioning system comprises a B-ultrasonic instrument or a magnetic resonance imager, and output control parameters of the upper computer and the transducer unit are adjusted according to an imaging result of the B-ultrasonic instrument or the magnetic resonance imager.
7. The focused ultrasound research platform as claimed in claim 1, wherein the display device comprises a high-speed camera and a projector, the high-speed camera and the projector are respectively disposed on the experiment operating platform, the high-speed camera is used for collecting image information during an experiment, and the projector is used for magnifying the image information during the collection experiment.
8. The focused ultrasound research platform according to claim 2, wherein the focused ultrasound equipment further comprises a regulated dc power supply, an output terminal of the regulated dc power supply is connected to an input terminal of the power source, and a voltage of the regulated dc power supply is adjustable.
CN201920350726.6U 2019-03-19 2019-03-19 Focused ultrasound scientific research platform Active CN210750947U (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109893785A (en) * 2019-03-19 2019-06-18 深圳市声科生物医学研究院 A kind of ultrasonic Scientific Research Platform of focusing

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109893785A (en) * 2019-03-19 2019-06-18 深圳市声科生物医学研究院 A kind of ultrasonic Scientific Research Platform of focusing

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