CN210708002U - AST-3424 injection filling, plugging and capping device with bottle outlet mechanism - Google Patents

Abstract

A pouring, plugging and capping device of AST-3424 injection with a bottle discharging mechanism belongs to the field of medicine packaging machinery, and comprises: a conveying mechanism; the liquid filling mechanism comprises a liquid filling needle head and a liquid medicine quantitative switch, is connected with the liquid storage tank and is used for quantitatively filling liquid medicine into an empty penicillin bottle at a liquid filling station; a feeding mechanism; the coating prepressing mechanism comprises a driving device and a prepressing die connected with the driving device; the plugging mechanism is used for pressing the rubber plug into the bottle mouth of the penicillin bottle which is pre-pressed with the covering layer and is positioned at the plugging station; the gland mechanism is used for rolling the aluminum cap on the plugged bottle mouth of the penicillin bottle at the gland station; the bottle discharging mechanism comprises a bottle pushing plate. The utility model discloses a device and method, its integrated completion liquid medicine fill, add stopper and gland problem, the packing bottle that obtains can solve and verify the gas tightness, verify whether the packing is destroyed and quick make the solvent of evaporation drip the problem in the bottle in the injection.

Description

AST-3424 injection filling, plugging and capping device with bottle outlet mechanism

Technical Field

The utility model relates to a fill in liquid medicine packing and add improvement of stopper capping device belongs to medicine packaging machinery field.

Background

As shown in fig. 5, a typical vial (see chinese utility model publication CN201445645U, published japanese patent No. 2010.05.05) includes a vial body 1, a plug 2 and a cover 3, and a protective cover 4 is sometimes disposed on the cover.

The liquid medicine in the industry, whether the liquid medicine is injection for injection administration or oral liquid for oral administration, is packaged by using the structure.

However, the above-mentioned package has a problem that it cannot be quickly known whether it is used or not by its appearance: in the case of injection or oral liquid, although removal of the protective cap means that the package is unsealed, it is not easy and quick to detect whether the liquid medicine is sucked or other substances are injected by the penetration of the syringe needle. Of course, it can be found by carefully observing the needle eye on the rubber plug 2, but it is time consuming and cumbersome.

In addition, for the sealing effect of the packaging bottle with the structure, the rubber plug is plugged on the bottle opening of the bottle body, and then the sealing cover 3 is added for fixing and pressing, but in long-time storage, if leakage occurs to cause liquid medicine deterioration, the liquid medicine cannot be rapidly and visually judged through naked eye observation.

SUMMERY OF THE UTILITY MODEL

The utility model provides a filling and plugging gland device of liquid medicine packing bottle with a protrusion, which integrally completes the filling, plugging and capping problems of the liquid medicine, and the obtained packing bottle can solve the two problems.

Traditional tectorial membrane plug is directly filled in the bottleneck, the utility model discloses a technique of "deformation pressfitting" is used to the plug of packing bottle, uses or does not use any adhesive or other auxiliaries: when the rubber plug is pressed, the elastic coating layer (membrane material) is arranged below the rubber plug, then the coating layer (membrane material) is pre-pressed to obtain a protruding structure, then the rubber plug is pressed, the coating layer (membrane material) is attached to the rubber plug and sealed by utilizing the deformation (plastic deformation and/or elastic deformation) of the membrane material in the pressing process, and the coating layer (membrane material) is attached to the rubber plug and sealed by utilizing the secondary deformation (plastic deformation and/or elastic deformation) of the coating layer (membrane material) in the pressing process to complete the pressing of the rubber plug. In the process, because the cavity is arranged between the concave structure of the rubber plug and the covering layer, in the rapid pressing process, gas (pressed in protective gas atmosphere) is pressed and sealed in the cavity and the protruding structure formed by the covering layer, so that the internal pressure is higher than the outside, and more obvious protrusion or bulge is formed.

The protrusions or bumps are designed for two purposes:

verifying the air tightness and verifying whether the package is damaged. Since the bulge is filled with the compressed gas, the height of the bulge which bulges outwards can be measured or marked (marked on the bottle body) according to the operating pressure in the capping operation, and the bulge can collapse due to the compressed gas leakage once the air tightness is not qualified or the bulge is punctured due to use (whether the bulge is used maliciously or normally). Therefore, whether the protruding bulge collapses or not and whether the bulge collapses or not and exceeds the mark which is arranged on the bottle body in advance can be observed to verify the air tightness, verify whether the package is damaged or not and verify whether the package is used or not.

Quickly dropping the evaporated solvent in the injection into the bottle body. Since the shape of the bulge of the protrusion is nearly "V" -shaped, a solvent (such as volatile ethanol or other liquid medicine containing volatile components) condensed by evaporation from the injection liquid in the bottle can be collected to the lowest point in the center by the bulge, and thus drip more quickly, so that the possibility of change in the concentration of the liquid medicine in the bottle is reduced.

The utility model provides a fill and plug capping device forms protrudingly on xiLin bottle bottleneck through covering a layer pre-compaction earlier, then adds stopper, gland completion embedment work again, can be so that the protruding more obvious of formation through the pre-compaction to better reach above-mentioned effect, the contrast of naked eye observation is also more convenient, swift.

Based on the above utility model thinking, the utility model provides a following experimental scheme.

The AST-3424 injection liquid pouring and capping device with bottle outlet mechanism includes:

the conveying mechanism is a rotating disc type and comprises a chuck capable of rotating selectively, and bayonets arranged on the chuck are used for clamping and fixing penicillin bottles and rotating the penicillin bottles to different stations;

the liquid filling mechanism comprises a liquid filling needle head and a liquid medicine quantitative switch, is connected with the liquid storage tank and is used for quantitatively filling liquid medicine into an empty penicillin bottle at a liquid filling station;

the feeding mechanism is used for conveying and placing the covering layer on the bottle mouth of the penicillin bottle filled with the liquid medicine at the pre-pressing station;

the coating prepressing mechanism comprises a driving device and a prepressing die connected with the driving device and is used for prepressing a coating placed on the mouth of a penicillin bottle at a prepressing station into a shape with an arc-shaped protrusion downwards;

the plugging mechanism is used for pressing the rubber plug into the bottle mouth of the penicillin bottle which is pre-pressed with the covering layer and is positioned at the plugging station; and

the gland mechanism is used for rolling the aluminum cap on the plugged bottle mouth of the penicillin bottle at the gland station;

the bottle discharging mechanism comprises a bottle pushing plate,

the bottle pulling plate is in a folded line shape or an arc shape facing the chuck, the tip end of the bottle pulling plate extends into the bayonet of the chuck,

when the chuck continues to rotate to a bottle discharging station corresponding to the bottle discharging mechanism, the bottle pulling plate extends into the striking bayonet to pull out the penicillin bottles clamped into the bayonet one by one, so that the bottle discharging process is completed.

The bottle pulling plate is used for pulling the bottles, compared with the prior art that the penicillin bottles are actively pushed out by using a grooved pulley mechanism, a manipulator or a push rod, the mechanical structure is simple, other active parts are not required to be arranged, the control is not required, and the control of the whole system is simplified.

The bottle pulling plate is made of soft and elastic materials, such as rubber.

The purpose of the conveying mechanism is to convey the empty penicillin bottles to a preset station in sequence.

Generally, there are two types of transport mechanisms: a disc type rotary conveying mechanism or a linear conveying mechanism.

The disc type conveying mechanism has the basic principle that a main turntable is arranged, chucks matched with penicillin bottles are arranged on the periphery of the main turntable, the penicillin bottles are clamped into bayonets of the chucks by a matched bottle unscrambler, and the penicillin bottles are conveyed to a preset station in rotation. Such mechanisms are commonly used, for example, a double-station penicillin bottle filling machine disclosed in chinese patent document CN206544899U, a liquid filling and plugging machine disclosed in CN206172956U, a bottle filling and plugging mechanism device disclosed in CN203558514U, a filling and sealing machine disclosed in CN207015615U, and a high-speed liquid filling and plugging machine disclosed in CN1431141A all use the disc type conveying mechanism to convey penicillin bottles.

The linear conveying mechanism is similar to the disc type conveying mechanism, and a structure with a bayonet is arranged on the conveying belt, so that the penicillin bottles are conveyed to a preset station through the movement (intermittent or continuous movement) of the conveying belt.

The liquid filling mechanism is a common injection type filling structure, and a liquid filling needle is driven by a cylinder, an electric cylinder and the like to be inserted into a bottle opening for filling. The pipeline of the liquid filling needle is connected with a quantitative switch to ensure that the filling quantity is a preset quantity every time.

And the feeding mechanism is used for conveying and placing the covering layer on the bottle mouth of the penicillin bottle filled with the liquid medicine at the pre-pressing station. In general, in a pharmaceutical packaging machine, feeding is performed in a relatively large number of ways, and feeding can be performed by an air cylinder, an electric cylinder, an electromagnet, a robot, or the like. And the utility model discloses in, because what carry is covering the layer, the scheme of consequently considering is installation sucking disc on simple manipulator, through the sucking disc absorption cover behind the layer rely on the manipulator will cover the layer and transport on the bottleneck of xiLin bottle.

The plugging mechanism and the capping mechanism use the existing structures, and the liquid filling and plugging machine disclosed in CN206172956U, the filling and sealing machine disclosed in CN207015615U and the high-speed liquid filling and plugging machine disclosed in CN1431141A all disclose corresponding structures and schemes. Generally, the plug adding mechanism is to plug rubber plugs of the arranged plugs (the rubber plugs can be uniformly arranged into a small end downwards through a spiral vibration plug arranging machine) into bottle openings of penicillin bottles, and the driving structure is generally an air cylinder. The gland mechanism directly presses the aluminum cover to the bottle mouth filled with the rubber plug, and then tightens up the lower end of the aluminum cover to ensure that the lower end is reduced and deformed so as to firmly fix the rubber plug at the bottle mouth.

The covering layer prepressing mechanism is used for prepressing the covering layer through a prepressing die to obtain a primary protruding shape.

Furthermore, the bayonet is towards one edge of dialling the bottle board is provided with the chamfer, and the design of chamfer is convenient for dial the bottle board and insert the bayonet and dial out the xiLin bottle.

Further, still include high-pressure gas and blow in the mechanism, it includes:

the supporting rod is fixed on the plugging station;

the air blowing ring is a hollow circular ring, the inner wall of the air blowing ring is provided with an air outlet hole which is communicated with a high-pressure air source through a pipeline, the inner diameter of the air blowing ring is larger than or equal to the bottle mouth of the penicillin bottle and is positioned on the bottle mouth,

when the penicillin bottle pre-pressed with the covering layer is conveyed to a plugging station by the conveying mechanism, the air blowing ring is just positioned on the bottle mouth and blows air,

and when the blowing ring blows high-pressure gas towards the covering layer with the arc-shaped protrusion shape, the plugging mechanism presses the plugging into the bottle mouth.

Like this blow in the mechanism through further design high-pressure gas, can add the stopper and blow in high-pressure gas in preceding protruding structure after the pre-compaction, like this when adding the stopper, can be so that the atmospheric pressure in the protrusion is bigger, and the protruding degree that corresponds is also more obvious to reach more audio-visual effect.

Furthermore, the air outlet is obliquely arranged downwards, and air can be better blown into the bottle mouth through the oblique arrangement.

Furthermore, the support rod is hollow and tubular and plays a role of a pipeline, one end of the support rod is communicated with the high-pressure air source, and the other end of the support rod is communicated with the air blowing ring.

Further, the pre-pressing die comprises a pressing ring and a male die sleeved in the pressing ring,

the upper end of the male die is connected with a first driving device, the press ring is connected with a second driving device,

the male die can slide up and down in the compression ring, the lower end of the male die is a raised cambered surface,

when the penicillin bottle is conveyed to a prepressing station, the second driving device drives the pressing ring to press the edge of the covering layer placed on the bottle mouth tightly and fix the lower bottle mouth, and the first driving device drives the male die to penetrate through the pressing ring to be pressed downwards to prepress the covering layer into a shape with an arc-shaped protrusion downwards.

Further, the ground of clamping ring is provided with the rubber packing ring of buffering usefulness. The addition of the rubber gasket allows the cover layer to be tightened without the cover layer being torn or torn by excessive or rapid downward pressure of the pre-mold.

Preferably, the first driving device and the second driving device are cylinders, electric cylinders or electromagnets.

Alternatively, the conveying mechanism is a disc-type rotary conveying mechanism or a linear conveying mechanism. Of course, screw-type conveying mechanisms can also be used.

The AST-3424 injection filling, plugging and capping device comprises the filling, plugging and capping device with the protruded liquid medicine packaging bottle, a liquid storage tank and a liquid filling pipeline communicated with the liquid storage tank,

wherein the liquid storage tank, the liquid filling pipeline and the liquid filling needle are 316-grade stainless steel parts;

or

The inner layers of the liquid storage tank, the liquid filling pipeline and the liquid filling needle, which are contacted with the liquid medicine, are polyvinylidene fluoride layers.

Further, the covering layer is a polyvinylidene fluoride layer,

the feeding mechanisms are all 316-grade stainless steel components; or the parts of the feeding mechanism contacting the liquid medicine are coated with polyvinylidene fluoride layers.

The fact that 316-grade stainless steel or polyvinylidene fluoride layer is used as the part of the filling and plugging gland device which is particularly required to be suitable for AST-3424 injection and is in direct contact with or possibly in contact with the liquid medicine is that experiments prove that the AST-3424 liquid medicine does not react with the two materials (8 hours or even 24 hours) to cause impurities to become stable for the AST-3424 liquid medicine.

Drawings

FIG. 1 is a schematic view of a liquid medicine packing bottle according to some embodiments of the present invention;

FIG. 2 is a schematic structural view of a liquid medicine packaging bottle with a stopper/cap according to some embodiments of the present invention;

FIG. 3 is a schematic view of a rubber plug assembly of a liquid medicine packaging bottle according to some embodiments of the present invention;

FIG. 4 is a schematic diagram of a pouring and capping device according to certain embodiments of the present invention;

FIG. 5 is a schematic structural view of a liquid filling mechanism in some embodiments of the present invention;

FIG. 6 is a schematic structural view of a high-pressure gas blowing mechanism according to some embodiments of the present invention;

FIG. 7 is a schematic diagram of a lamination pre-press mechanism in accordance with certain embodiments of the present invention;

FIG. 8 is a schematic diagram illustrating the steps of a method for filling vials with caps according to certain embodiments of the present invention;

FIG. 9 is a schematic diagram of a bottle ejection mechanism according to certain embodiments of the present disclosure; and

fig. 10 is a schematic diagram illustrating the operation of filling and capping a vial using the filling and capping device according to this embodiment.

Detailed Description

As shown in fig. 1, 2 and 3, a medicine packaging bottle 100 comprises a bottle body 10, a rubber plug assembly 20 and a sealing cover 30.

As shown in fig. 2, the bottle body 10 for containing a medical solution includes a bottle neck 12 connecting a bottle body 11 and the bottle body 11, and a bottle mouth 13 is provided at an opening of the bottle neck.

The shape of the bottle 10 is optional depending on the application, and is generally cylindrical or rectangular. Moreover, the bottle neck 12 is generally smaller than the bottle body 11, and the specific shape is shown in fig. 2.

The rubber plug assembly 20, which is used for being plugged into the bottle mouth 11 of the bottle body 10, comprises a rubber plug 21 and a coating layer 22 directly attached to the exposed surface of the rubber plug facing the bottle mouth, and an adhesive layer or an inert adhesive layer is not used between the coating layer and the rubber plug.

The coating layer 22 is a medical elastic polymer material layer, and the coating layer 22 is preferably made of polyethersulfone resin PES, polytetrafluoroethylene PTFE, polyvinylidene fluoride PVDF, or tetrafluoroethylene/hexafluoropropylene copolymer FEP film material. The rubber plug 21 is made of elastic material.

As shown in fig. 1, the sealing cap 30 is used for being disposed on the rubber plug assembly 20 to fix the bottle mouth 13 and the rubber plug assembly 20 in a snap-fit manner.

As shown in fig. 2, an annular upper end of the ring is sleeved on the rubber plug assembly 20, while the lower end thereof is clamped on the bottle neck 12, and the bottle neck 12 is provided with a ring of recesses 122 for clamping and fixing the lower end of the sealing cover 30, so that the rubber plug assembly 20 can be firmly plugged and fixed in the bottle mouth 13.

The cover 30 is typically made of aluminum. The top of the sealing cover 30 forms a notch 31 (circular hole) to expose the rubber plug 21 for easy puncturing.

As shown in fig. 3, the rubber plug 21 includes a base 211 and a plug body 212 connected to the base, and the outer end surface of the plug body 212 has a concave structure 213.

Correspondingly, the covering layer 22 is bonded to at least the surface of the plug body 212, but not to the inner wall formed by the recessed structure 213, so that a closed cavity 214 is formed between the recessed structure 213 and the covering layer 22.

As shown in fig. 1, the coating layer 22 is formed to protrude outward by the action of the compressed gas contained in the closed cavity 214 formed between the recess structure 213 and the coating layer 22.

Specific example 2

As shown in fig. 1, the packing bottle 100 further includes a protective cap 40, the protective cap 40 having a cylindrical cap portion 41 and a ring-shaped neck-receiving portion 42 connected to the cylindrical cap portion, the cylindrical cap portion 41 covering the base 211, and the neck-receiving portion 42 covering the mouth 13.

The protective cover 40 is engaged with and covers a notch 31 (circular hole) formed at the top of the cover 30 so that the exposed rubber stopper 21 is covered.

Specific example 3

As the invention has been invented, in order to make the position change of the bulge or protrusion more intuitive, a scale mark is provided on the body 11 or neck 12 of the bottle (vial) to mark the design position of the bulge or bulge. As shown in fig. 1, the graduation marks 121 are a ground ring band 1.5mm wide and the band is ground at intervals to facilitate viewing of the alignment of the protrusions or bumps.

The above embodiments show the structure of the liquid medicine packaging bottle with the protrusion, and the following embodiments specifically describe the specific structure of the pouring, plugging and capping device of the liquid medicine packaging bottle with the protrusion provided by the present invention.

Specific example 4

As shown in fig. 4, the filling, capping and capping device 1000 for a medicine packing bottle having a protrusion includes:

and the conveying mechanism 200 is used for clamping and fixing the penicillin bottles and moving the penicillin bottles to different stations. In the embodiment, a disc type conveying mechanism with a compact structure is selected, the basic principle is that a main turntable 210 is arranged, chucks 220 matched with penicillin bottles are arranged on the periphery of the main turntable, the penicillin bottles are clamped into bayonets of the chucks by a matched bottle unscrambler LB, and the penicillin bottles are conveyed to a preset station in rotation. Correspondingly, the predetermined stations are also arranged according to the circumference. Certainly, the number of bayonets driven and rotated by a driving machine (stepping motor) corresponding to the conveying mechanism 10 is different according to the difference of the corresponding action mechanisms arranged on each station, and is simple, for example, if 60 bayonets are arranged on one chuck 220, the corresponding angle of each corresponding bayonet is 6 degrees, if 10 liquid filling mechanisms 300, a feeding mechanism 400, a laminating pre-pressing mechanism 500, a plugging mechanism 600 and a capping mechanism 700 are arranged on one station to perform corresponding operations at the same time, the driving machine drives the rotary table 210 to rotate 60 degrees each time; if a station is provided with 5 of the various mechanisms described above, the drive machine drives the turntable 210 to rotate 30 degrees at a time, and so on. In this embodiment, one chuck 220 is provided with 30 bayonets 221, and the corresponding angle of each corresponding bayonet is 12 degrees, and one station is provided with 1 liquid filling mechanism 300, a feeding mechanism 400, a laminating pre-pressing mechanism 500, a plugging mechanism 600, and a capping mechanism 700 to perform corresponding operations simultaneously, so that the driver drives the turntable 210 to rotate 12 degrees each time.

The liquid filling mechanism 300 comprises a liquid filling needle 310 and a liquid medicine quantitative switch 320, is connected with the liquid storage tank C, and is used for quantitatively filling liquid medicine into an empty penicillin bottle at a liquid filling station. The conventional structure scheme is used in this embodiment, as shown in fig. 5: the liquid medicine in the liquid storage tank C storing the injection is quantitatively injected into the empty vial through the filling needle 310 under the action of the pump and the liquid medicine quantitative switch 320.

And the feeding mechanism 400 is used for conveying and placing the covering layer on the bottle mouth of the penicillin bottle filled with the liquid medicine at the pre-pressing station. The feeding mechanism of the embodiment is to convey the covering layer, so that the sucker is arranged on the simple mechanical arm, and the covering layer is sucked by the sucker and then transferred to the bottle mouth of the penicillin bottle by the mechanical arm.

The coating prepressing mechanism 500 comprises a driving device 510 and a prepressing die 520 connected with the driving device, and is used for prepressing the coating placed on the mouth of the penicillin bottle at the prepressing station into a shape with an arc-shaped protrusion downwards.

And the plugging mechanism 600 is used for pressing the rubber plug into the bottle mouth of the penicillin bottle which is pre-pressed with the covering layer and is positioned at the plugging station.

And the gland mechanism 700 is used for rolling the aluminum cap onto the plugged bottle mouth of the penicillin bottle at the gland station.

The bottle discharging mechanism 900 comprises a bottle pulling plate 910, which is in a folded line shape or an arc shape facing the chuck, the tip end of the bottle pulling plate extends into the bayonet of the chuck,

when the chuck continues to rotate to a bottle discharging station corresponding to the bottle discharging mechanism, the bottle pulling plate extends into the striking bayonet to pull out the penicillin bottles clamped into the bayonet one by one, so that the bottle discharging process is completed.

The plugging mechanism and the capping mechanism use the structures supplied on the market, and the liquid filling and plugging machine disclosed in CN206172956U, the filling and sealing machine disclosed in CN207015615U and the high-speed liquid filling and plugging machine disclosed in CN1431141A all disclose corresponding structures and schemes. Generally, the plug adding mechanism is to plug rubber plugs of the arranged plugs (the rubber plugs can be uniformly arranged into a small end downwards through a spiral vibration plug arranging machine) into bottle openings of penicillin bottles, and the driving structure is generally an air cylinder. The gland mechanism directly presses the aluminum cover to the bottle mouth filled with the rubber plug, and then tightens up the lower end of the aluminum cover to ensure that the lower end is reduced and deformed so as to firmly fix the rubber plug at the bottle mouth.

Specific example 5

As shown in fig. 4/6, embodiment 4 further includes a high-pressure gas blowing mechanism 800 including:

and the supporting rod 810 is fixed on the plugging station.

And the air blowing ring 820 is a hollow circular ring, the inner wall of the air blowing ring is provided with an air outlet 821, the air blowing ring is communicated with a high-pressure air source G through a pipeline, and the inner diameter of the air blowing ring is larger than or equal to the bottle mouth of the penicillin bottle and is positioned on the bottle mouth.

When the penicillin bottle pre-pressed with the covering layer is conveyed to a plugging station by the conveying mechanism 200, the air blowing ring is just positioned on the bottle mouth and blows air, and when the air blowing ring 820 blows high-pressure air towards the covering layer with the arc-shaped protrusion shape, the plugging mechanism 600 presses the rubber plug into the bottle mouth.

Specific example 6

On the basis of the above embodiments 4 and/or 5, the air outlet is arranged obliquely downward, specifically, a hole is arranged on the inner wall of the blowing ring, and then the short pipe is welded to arrange the short pipe obliquely downward.

Detailed description of preferred embodiments 7

On the basis of the above embodiments 4 and/or 5 and/or 6, the supporting rod 810 is a hollow pipe, and functions as a pipeline, one end of the supporting rod is communicated with the high-pressure air source, and the other end of the supporting rod is communicated with the blowing ring.

Specific example 8

On the basis of the above embodiments 4 and/or 5 and/or 6 and/or 7, as shown in fig. 7, wherein the driving device 510 is disposed on the support 530, the support 530 is fixed on the pre-pressing station. The pre-pressing die 520 includes a pressing ring 521 and a male die 522 sleeved in the pressing ring.

The upper end of the male die 522 is connected with the first driving device 511, and the pressing ring 521 is connected with the second driving device 512. The male die 522 can slide up and down in the press ring 521, and the lower end of the male die is a convex cambered surface.

When the penicillin bottle is conveyed to a pre-pressing station, the second driving device 512 drives the pressing ring 521 to press the edge of the covering layer placed on the bottleneck tightly against the lower bottleneck, and the first driving device 511 drives the male die 522 to pass through the pressing ring 521 to press downwards to pre-press the covering layer 22 into a shape with an arc-shaped protrusion downwards.

Specific example 9

On the basis of the above embodiments 4 and/or 5 and/or 6 and/or 7 and/or 8, the bottom surface of the pressing ring 521 is provided with a rubber gasket for buffering.

Detailed description of example 10

On the basis of the above embodiments 4 and/or 5 and/or 6 and/or 7 and/or 8 and/or 9, the first driving device 511 and the second driving device 512 are air cylinders or electric cylinders or electromagnets or electric push rods.

Since the first driving device 511 is used for driving the male die 522 to perform film pressing, the speed and force of the male die during the film pressing process will directly affect the pressed shape of the overlay, and too fast or too large force will cause tension fracture or breaking, it is preferable to use an electric cylinder, preferably a servo electric cylinder, for the first driving device 511, which can precisely control the force and the action speed.

Specific example 11

The injection filling, plugging and capping device for AST-3424 comprises the injection filling, plugging and capping device with a protruded liquid medicine packaging bottle of any one of the above embodiments 4-10, a liquid storage tank C and a liquid filling pipeline G communicated with the liquid storage tank, wherein the liquid storage tank C, the liquid filling pipeline G and the liquid filling needle 310 are all 316-brand stainless steel components; or the inner layers of the liquid storage tank C, the liquid filling pipeline and the liquid filling needle head 310, which are in contact with the liquid medicine, are polyvinylidene fluoride layers.

Detailed description of example 12

On the basis of the embodiment 10, the covering layer is a polyvinylidene fluoride layer,

the feeding mechanisms 400 are all 316-grade stainless steel components; or the parts of the feeding mechanism 400 contacting the liquid medicine are coated with polyvinylidene fluoride layers.

Specific example 13

As shown in fig. 8, the method for pouring, plugging and capping penicillin bottles of this embodiment sequentially includes a liquid filling step S1, a coating layer prepressing step S2, a plugging step S3 and a capping step S4.

And a liquid filling step S1, filling a liquid medicine with a preset volume into the penicillin bottle through a liquid filling mechanism.

And a coating layer prepressing step S2, after the liquid medicine is filled into the penicillin bottle, prepressing and forming the coating layer to enable the coating layer to be attached to the mouth of the penicillin bottle and form a structure protruding into the mouth.

Preferably, in the coating layer prepressing, the coating layer placed on the bottle mouth is fixed and then is prepressed by using a male die.

And a step S3 of plugging, namely, quickly pressing the rubber plug into the bottle mouth with the coating layer. Fast is a speed within 0.1 second or faster.

And a step S4 of pressing the cover, namely directly pressing the aluminum cover on the bottle mouth filled with the rubber plug, and then tightening the lower end of the aluminum cover to ensure that the lower end is reduced and deformed so as to firmly fix the rubber plug on the bottle mouth.

The operation of the whole device will be described with reference to fig. 4 and fig. 8 and 10.

The cleared and cleaned penicillin bottles are slowly pushed into the bayonet of the chuck 220 by a push rod of the bottle straightening machine in a hopper LD of the bottle straightening machine L. Then the liquid is conveyed by a chuck of the conveying mechanism 200 and is filled by a liquid filling mechanism when the liquid is conveyed to a liquid filling station corresponding to the liquid filling mechanism 300 (figure a);

the chuck continues to rotate, the filled penicillin bottle is conveyed to a striking prepressing station, the feeding mechanism 400 acts, and the covering layer 22 is placed at the penicillin bottle mouth (figure b);

after the covering layer is placed, the pressing ring 521 of the covering layer prepressing mechanism 500 is driven to fix the periphery of the covering layer on the penicillin bottle mouth (figure c), and then the male die 522 is driven to prepress and form the covering layer (figure d);

the chuck continues to rotate, the penicillin bottle is conveyed to a plugging station, the high-pressure gas blowing mechanism 800 performs blowing (figure e), and the plugging mechanism 600 presses the rubber plug (figure f) after the high-pressure gas blowing mechanism leaves;

after the chuck rotates to convey the plugged penicillin bottles to the capping station, the capping mechanism 700 acts to complete capping (g diagram), the protective cover pressing mechanism BH presses the protective covers (h diagram), and finally the packaging bottles shown in fig. 2 are obtained.

The chuck of the conveying mechanism 200 continues to rotate, and the capped penicillin bottles are conveyed to the bottle discharging mechanism 900.

As shown in fig. 9, a bottle pulling plate is disposed at an edge of the hopper LD, the bottle pulling plate 910 is in a shape of a broken line or an arc facing the chuck 220, and a tip thereof extends into the bayonet 221 of the chuck 220, and a corresponding edge of the bayonet facing the bottle pulling plate is provided with a chamfer (a round chamfer or a right-angle chamfer), which is designed to facilitate the bottle pulling plate to be inserted into the bayonet 221 to pull out the vial.

When the chuck 220 continues to rotate to a station corresponding to the bottle discharging mechanism 900, the bottle pulling plate 910 pulls out the vials that are clamped in the clamping opening 221 one by one and enters the bottle discharging channel 920, so that the bottle discharging process is completed.

Claims (11)

1. The AST-3424 injection liquid pouring and capping device with bottle outlet mechanism includes:

the conveying mechanism is a rotating disc type and comprises a chuck capable of rotating selectively, and bayonets arranged on the chuck are used for clamping and fixing penicillin bottles and rotating the penicillin bottles to different stations;

the liquid filling mechanism comprises a liquid filling needle head and a liquid medicine quantitative switch, is connected with the liquid storage tank and is used for quantitatively filling liquid medicine into an empty penicillin bottle at a liquid filling station;

the feeding mechanism is used for conveying and placing the covering layer on the bottle mouth of the penicillin bottle filled with the liquid medicine at the pre-pressing station;

the coating prepressing mechanism comprises a driving device and a prepressing die connected with the driving device and is used for prepressing a coating placed on the mouth of a penicillin bottle at a prepressing station into a shape with an arc-shaped protrusion downwards;

the plugging mechanism is used for pressing the rubber plug into the bottle mouth of the penicillin bottle which is pre-pressed with the covering layer and is positioned at the plugging station; and

the gland mechanism is used for rolling the aluminum cap on the plugged bottle mouth of the penicillin bottle at the gland station;

the bottle discharging mechanism comprises a bottle pushing plate,

the bottle pulling plate is in a folded line shape or an arc shape facing the chuck, the tip end of the bottle pulling plate extends into the bayonet of the chuck,

when the chuck continues to rotate to a bottle discharging station corresponding to the bottle discharging mechanism, the bottle pulling plate extends into the striking bayonet to pull out the penicillin bottles clamped into the bayonet one by one, so that the bottle discharging process is completed.

2. The AST-3424 injection liquid filling and capping device with a bottle discharging mechanism of claim 1, wherein an edge of the bayonet facing the bottle pulling plate is provided with a chamfer designed to facilitate insertion of the bottle pulling plate into the bayonet to pull out the vial.

3. The apparatus of claim 1 further comprising a high pressure gas blowing mechanism comprising:

the supporting rod is fixed on the plugging station;

the air blowing ring is a hollow circular ring, the inner wall of the air blowing ring is provided with an air outlet hole which is communicated with a high-pressure air source through a pipeline, the inner diameter of the air blowing ring is larger than or equal to the bottle mouth of the penicillin bottle and is positioned on the bottle mouth,

when the penicillin bottle pre-pressed with the covering layer is conveyed to a plugging station by the conveying mechanism, the air blowing ring is just positioned on the bottle mouth and blows air,

and when the blowing ring blows high-pressure gas towards the covering layer with the arc-shaped protrusion shape, the plugging mechanism presses the plugging into the bottle mouth.

4. The AST-3424 injection liquid pouring capping device with bottle out mechanism of claim 3, wherein said air outlet is obliquely downward disposed.

5. The apparatus of claim 3 wherein said support rod is hollow and tubular and acts as a conduit, one end of said support rod being in communication with said high pressure gas source and the other end of said support rod being in communication with said insufflation ring.

6. The AST-3424 injection liquid pouring and capping device with bottle discharging mechanism of claim 1, wherein the pre-pressing mold comprises a pressing ring and a male mold nested inside the pressing ring,

the upper end of the male die is connected with a first driving device, the press ring is connected with a second driving device,

the male die can slide up and down in the compression ring, the lower end of the male die is a raised cambered surface,

when the penicillin bottle is conveyed to a prepressing station, the second driving device drives the pressing ring to press the edge of the covering layer placed on the bottle mouth tightly and fix the lower bottle mouth, and the first driving device drives the male die to penetrate through the pressing ring to be pressed downwards to prepress the covering layer into a shape with an arc-shaped protrusion downwards.

7. The AST-3424 injection liquid pouring capping device with bottle discharging mechanism of claim 6, wherein the floor of the pressing ring is provided with a rubber gasket for buffering.

8. The AST-3424 injection liquid pouring capping device with bottle discharging mechanism of claim 6, wherein said first driving means, said second driving means are air cylinder or electric cylinder or electromagnet.

9. The AST-3424 injection liquid pouring capping device with bottle discharging mechanism of claim 1, wherein the conveying mechanism is a disc type rotating conveying mechanism or a linear conveying mechanism.

10. The injection filling and capping device for AST-3424 with the bottle discharging mechanism comprises the injection filling and capping device for AST-3424 with the bottle discharging mechanism, a liquid storage tank and a liquid filling pipeline communicated with the liquid storage tank, wherein the injection filling and capping device for AST-3424 with the bottle discharging mechanism comprises any one of the devices 1 to 8,

wherein the liquid storage tank, the liquid filling pipeline and the liquid filling needle are 316-grade stainless steel parts;

or

The inner layers of the liquid storage tank, the liquid filling pipeline and the liquid filling needle, which are contacted with the liquid medicine, are polyvinylidene fluoride layers.

11. The AST-3424 injection liquid pouring capping device with bottle discharging mechanism of claim 10, wherein the covering layer is a polyvinylidene fluoride layer,

the feeding mechanisms are all 316-grade stainless steel components; or the parts of the feeding mechanism contacting the liquid medicine are coated with polyvinylidene fluoride layers.

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