CN210674313U

CN210674313U - Simple detection solid-phase extraction device

Info

Publication number: CN210674313U
Application number: CN201921320049.XU
Authority: CN
Inventors: 郝云彬
Original assignee: Zhejiang Ruide Anzheng Testing And Certification Technology Co Ltd
Current assignee: Zhejiang Ruide Anzheng Testing And Certification Technology Co Ltd
Priority date: 2019-08-14
Filing date: 2019-08-14
Publication date: 2020-06-05
Anticipated expiration: 2029-08-14

Abstract

The utility model provides a simply detect solid phase extraction device belongs to the extraction device field, including mount, first bracing piece, second bracing piece and liquid feeding pipe, transit tube, the extraction tube that from top to bottom set up. The plurality of transit pipes are fixed on the second supporting rod, the bottom of each transit pipe is connected with a hose, and a flow rate regulator is arranged on each hose. The improved liquid feeding device is characterized in that a sliding block is sleeved on the first supporting rod, a groove is formed in the sliding block, a clamping block is fixed on the side wall of the liquid feeding pipe, and the liquid feeding pipe passes through the clamping block and is clamped on the groove. Reagent is added into the transfer tube through the liquid adding tube, and then the reagent is added into the extraction tube through the transfer tube. Because the liquid feeding pipe slides and changes simply, can quick replacement liquid feeding pipe when the reagent that needs the difference, because set up the velocity of flow regulator on the transfer pipe, can be according to the demand adjusting reagent's of different extraction reactions add speed, be favorable to the reaction to go on high-efficiently.

Description

Simple detection solid-phase extraction device

Technical Field

The utility model relates to an extraction device field especially relates to a simply detect solid phase extraction device.

Background

Solid phase extraction (SPE for short) is a sample pretreatment technology which is rapidly developed in recent years and is developed by combining liquid-solid extraction and liquid column chromatography. The technology is mainly applied to separation, purification and concentration of samples, can improve the recovery rate of analytes compared with the traditional liquid-liquid extraction method, more effectively separates the analytes from interfering components, reduces the sample pretreatment process, and is simple to operate, time-saving and labor-saving. In the solid phase extraction, 4 steps of activation, loading, leaching and elution are mainly needed. During the activation and elution process, reagents are added to the activation tube. The different samples require different types of reagents and different reagent adding speeds, and the extraction effect is affected if the reagents cannot be added at proper speeds. In the conventional method, different reagents can be added to different samples only by manually adopting different droppers, the efficiency is not high, and the adding speed is difficult to control.

SUMMERY OF THE UTILITY MODEL

In order to overcome the defects of the prior art, the utility model aims to solve the technical problem that a simply detect solid phase extraction device is proposed, it carries out the liquid feeding for the transit pipe of difference through slidable liquid feeding pipe, adds to the extraction tube by the transit pipe again in, and the output speed of transit pipe can be adjusted in a flexible way.

To achieve the purpose, the utility model adopts the following technical proposal:

the utility model provides a simply detect solid phase extraction device, including mount, first bracing piece, second bracing piece and liquid feeding pipe, transit pipe, the extraction tube that from top to bottom set up. The upper surface of mount has seted up a plurality of through-holes, the extraction tube place in on the through-hole, first bracing piece the equal level of second bracing piece is fixed in on the mount, just first bracing piece is located second bracing piece top. The plurality of transfer pipes are fixed on the second supporting rod, one extraction pipe corresponds to each transfer pipe, the bottom of each transfer pipe is connected with a hose, and a flow rate regulator is arranged on each hose. The improved liquid adding device is characterized in that a sliding block is sleeved on the first supporting rod, a groove is formed in the sliding block, a clamping block is fixed on the side wall of the liquid adding pipe, the liquid adding pipe passes through the clamping block and is clamped on the groove, and a pressure ball is arranged on the liquid adding pipe.

The utility model discloses in the technical scheme of preferred, be provided with on the through-hole and be used for the chucking the rubber ring of extraction tube, the rubber ring is higher than the upper surface of mount.

In the preferred technical scheme of the utility model, the front and back end faces of the fixing frame are all fixed with glass plates. The glass plate and the fixing frame form a sealed space.

The utility model discloses in the technical scheme of preferred, the spirit level has been inlayed on the second bracing piece.

The utility model discloses in the technical scheme of preferred, be provided with the capacity scale on the pipe wall of transit pipe.

The utility model discloses in the technical scheme of preferred, the both ends of second bracing piece are provided with the screw clamp, the second bracing piece passes through the screw clamp to be fixed on the mount.

The utility model discloses in the technical scheme of preferred, the bottom of extraction tube is connected with the fluid-discharge tube, the fluid-discharge tube runs through the bottom of mount extends to the outside of mount.

The utility model discloses in the technical scheme of preferred, threaded connection has on the slider be used for with the slider with the tight knob of first bracing piece clamp.

The utility model has the advantages that:

the utility model provides a pair of simply detect solid phase extraction device adds reagent toward the transfer pipe through the liquid feeding pipe, adds reagent toward the extraction tube via the transfer pipe again. Because the liquid feeding pipe slides and changes simply, can quick replacement liquid feeding pipe when the reagent that needs the difference, because set up the velocity of flow regulator on the transfer pipe, can be according to the demand adjusting reagent's of different extraction reactions add speed, be favorable to the reaction to go on high-efficiently.

Drawings

FIG. 1 is a schematic structural diagram of a simple detection solid-phase extraction apparatus according to an embodiment of the present invention;

FIG. 2 is a schematic diagram of a side view of a first supporting rod of the simple detection solid-phase extraction device according to an embodiment of the present invention;

in the figure:

1. the device comprises a fixed frame, 11, a first supporting rod, 12, a second supporting rod, 13, a through hole, 14, a rubber ring, 15, a level gauge, 16, a spiral clamp, 2, a liquid feeding pipe, 21, a pressure ball, 3, a transfer pipe, 31, a hose, 32, a flow rate regulator, 33, a scale 4, an extraction pipe, 41, a liquid discharge pipe, 51, a sliding block, 52, a groove, 53, a clamping block, 54 and a knob.

Detailed Description

The technical solution of the present invention is further explained by the following embodiments with reference to the accompanying drawings.

As shown in fig. 1 and fig. 2, the embodiment provides a simple detection solid phase extraction apparatus, which includes a fixing frame 1, a first support rod 11, a second support rod 12, and a liquid feeding tube 2, a transit tube 3, and an extraction tube 4 arranged from top to bottom. A plurality of through holes 13 are formed in the upper surface of the fixing frame 1, the extraction tube 4 is placed on the through holes 13, the first supporting rod 11 and the second supporting rod 12 are horizontally fixed on the fixing frame 1, and the first supporting rod 11 is located above the second supporting rod 12. The plurality of transit pipes 3 are fixed on the second support rod 12, one extraction pipe 4 corresponds to each transit pipe 3, a hose 31 is connected to the bottom of each transit pipe 3, and a flow rate regulator 32 is arranged on each hose 31. The utility model discloses a liquid feeding pipe, including first bracing piece 11, first bracing piece is equipped with slider 51 on the cover, seted up recess 52 on the slider 51, be fixed with fixture block 53 on the lateral wall of liquid feeding pipe 2, liquid feeding pipe 2 passes through fixture block 53 joint in on the recess 52, be provided with pressure ball 21 on the liquid feeding pipe 2.

The original sample is stored in the extraction tube 4 in the embodiment, and different samples are put into different extraction tubes 4, so that the device can be used for simultaneously extracting multiple different samples. Depending on the sample, the reagents required for solid phase extraction will vary. At this time, the required reagents can be added into different liquid adding pipes 2 according to the requirements of different samples. After a reagent is added into the liquid feeding tube 2, the block 53 on the liquid feeding tube 2 is clamped on the groove 52 of the slide block 51, and the slide block 51 can slide on the first support rod 11. Each extraction tube 4 is provided with a corresponding transfer tube 3, the liquid adding tube 2 is slid onto the corresponding transfer tube 3, and a certain amount of reagent is dripped into the liquid adding tube 2. If other samples also need the same reagents for extraction, the filling tube 2 can be slid further onto the corresponding transfer tube 3 for filling. If the reagent needs to be replaced, the filling tube 2 is directly taken out from the slide block 51, and the filling tube 2 filled with different reagents is clamped on the slide block 51 for filling according to the method. The effects of quick replacement and reagent addition are realized, and the working efficiency is improved.

After the liquid adding of each transfer tube 3 is completed, the user can adjust the speed of the transfer tube 3 for outputting the reagent to the extraction tube 4 according to the liquid adding speed required by the extraction reaction. The reagent in the transfer tube 3 flows into the extraction tube 4 through the hose 31. The flow rate regulator 32 provided on the flexible tube 31 can adjust the flow rate of the reagent output from the flexible tube 31. The flow rate regulator 32 in this embodiment is the same as the flow rate regulator 32 in the medical infusion set. The flow rate regulator 32 regulates the flow rate by regulating the tightness of the clamp hose 31. Besides, other devices capable of adjusting the clamping tightness can be adopted for flow rate adjustment. The function of adjusting the reagent adding speed is realized, and the extraction is favorably and efficiently carried out.

In an embodiment of the present invention, the through hole 13 is provided with a rubber ring 14 for clamping the extraction tube 4, and the rubber ring 14 is higher than the upper surface of the fixing frame 1. The rubber ring 14 can increase the friction force between the through hole 13 and the extraction tube 4, so that the extraction tube 4 can be more stably placed on the through hole 13.

In an embodiment of the present invention, glass plates are fixed to the front and rear end surfaces of the fixing frame 1. The glass plate and the fixing frame 1 form a sealed space. The glass plate can prevent the extraction tube 4 from being touched accidentally in the extraction process, thereby influencing the extraction. In addition, in some reactions, a violent exotherm or endotherm may occur, which may be scalded or frozen if the extraction tube 4 is touched inadvertently, and which may be prevented by the glass plate.

In an embodiment of the present invention, the second support rod 12 is embedded with a level 15, and the wall of the transit tube 3 is provided with a volume scale 33. The staff also can know the volume of reagent that adds according to the scale 33 value on transit tube 3, can stop reagent to add in time as required. The level gauge 15 can reflect whether the second support rod 12 is horizontal or not, and if not, the level gauge will affect the reading of the transit tube 3 and cause reaction errors. The worker can adjust the second support pole 12 to the horizontal through the level gauge 15.

In an embodiment of the present invention, the two ends of the second supporting rod 12 are provided with screw clamps 16, the second supporting rod 12 is fixed by the screw clamps 16, and the screw clamps 16 are loosened on the fixing frame 1 to move the second supporting rod 12 up and down along the fixing frame 1, so that the second supporting rod 12 is adjusted to be horizontal. After the reaction is completed, the second support rod 12 can be pulled up, so that the extraction tube 4 can be taken out conveniently.

In an embodiment of the present invention, a drain pipe 41 is connected to the bottom of the extraction tube 4, and the drain pipe 41 extends through the bottom of the fixing frame 1 to the outside of the fixing frame 1. The drain 41 is closed while the extraction is in progress, and is opened after the reaction is completed to facilitate the draining of the tube.

In an embodiment of the present invention, a knob 54 for clamping the slider 51 and the first support rod 11 is screwed on the slider 51. After the sliding block 51 drives the liquid feeding pipe 2 to move to a proper position, in the process of feeding liquid to the transfer pipe 3, the sliding block 51 can be fixed on the first supporting rod 11 by screwing the knob 54, so that the sliding in the liquid feeding process is prevented.

While the invention has been described with reference to a preferred embodiment, it will be understood by those skilled in the art that various changes may be made and equivalents may be substituted for elements thereof without departing from the spirit and scope of the invention. The present invention is not to be limited by the specific embodiments disclosed herein, and other embodiments that fall within the scope of the claims of the present application are intended to be within the scope of the present invention.

Claims

1. The utility model provides a simple and easy detection solid phase extraction device which characterized in that: comprises a fixed frame (1), a first supporting rod (11), a second supporting rod (12), and a liquid feeding pipe (2), a transit pipe (3) and an extraction pipe (4) which are arranged from top to bottom;

the upper surface of the fixing frame (1) is provided with a plurality of through holes (13), the extraction tube (4) is placed on the through holes (13), the first supporting rod (11) and the second supporting rod (12) are horizontally fixed on the fixing frame (1), and the first supporting rod (11) is positioned above the second supporting rod (12);

the plurality of transit pipes (3) are fixed on the second support rod (12), each transit pipe (3) corresponds to one extraction pipe (4), the bottom of each transit pipe (3) is connected with a hose (31), and a flow rate regulator (32) is arranged on each hose (31);

the improved liquid filling device is characterized in that a sliding block (51) is sleeved on the first supporting rod (11), a groove (52) is formed in the sliding block (51), a clamping block (53) is fixed on the side wall of the liquid filling pipe (2), the liquid filling pipe (2) passes through the clamping block (53) in a clamping mode on the groove (52), and a pressure ball (21) is arranged on the liquid filling pipe (2).

2. The device for simple detection of solid phase extraction according to claim 1, wherein: the through hole (13) is provided with a rubber ring (14) used for clamping the extraction tube (4), and the rubber ring (14) is higher than the upper surface of the fixing frame (1).

3. The device for simple detection of solid phase extraction according to claim 1, wherein: glass plates are fixed on the front end face and the rear end face of the fixing frame (1); the glass plate and the fixing frame (1) form a sealed space.

4. The device for simple detection of solid phase extraction according to claim 1, wherein: a level (15) is embedded on the second supporting rod (12), and/or,

the pipe wall of the transit pipe (3) is provided with capacity scales (33).

5. The device for simple detection of solid phase extraction according to claim 4, wherein: screw clamps (16) are arranged at two ends of the second supporting rod (12), and the second supporting rod (12) is fixed on the fixing frame (1) through the screw clamps (16).

6. The device for simple detection of solid phase extraction according to claim 1, wherein: the bottom of the extraction pipe (4) is connected with a liquid discharge pipe (41), and the liquid discharge pipe (41) penetrates through the bottom of the fixing frame (1) and extends to the outside of the fixing frame (1).

7. The device for simple detection of solid phase extraction according to claim 1, wherein: the sliding block (51) is in threaded connection with a knob (54) used for clamping the sliding block (51) and the first supporting rod (11).