CN210673507U - Silica gel nose-humping prosthesis - Google Patents
Silica gel nose-humping prosthesis Download PDFInfo
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- CN210673507U CN210673507U CN201920130597.XU CN201920130597U CN210673507U CN 210673507 U CN210673507 U CN 210673507U CN 201920130597 U CN201920130597 U CN 201920130597U CN 210673507 U CN210673507 U CN 210673507U
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Abstract
The utility model discloses a silica gel augmentation rhinoplasty, silica gel augmentation rhinoplasty include nose back part, nose point part and columella nasalis part, nose point part is the form of buckling, nose back part and columella nasalis part are connected respectively in the both ends of nose point part, nose back part, nose point part and columella nasalis part all are three-dimensional network structure, and whole silica gel augmentation rhinoplasty prints integrated into one piece through 3D, and it wholly is "L" shape. The utility model discloses in according to human three-dimensional CT data of nose or the photographic data of 3D, reunion patient demand and operation scheme use silica gel 3D to print the customization and form, the operation effect can predict in advance, it is accurate and individualized, reduce the deviation that leads to because of subjective factors such as doctor's sculpture technique, aesthetic, practice thrift the operation time simultaneously, the prosthesis is good with nose tissue matching nature, reduced skew after the prosthesis is implanted, rock, the different position elastic modulus's of nasal part demand can be satisfied to the false body of silica gel augmentation nose.
Description
Technical Field
The utility model relates to a silica gel nose augmentation prosthesis, which belongs to the field of medical appliance manufacturing.
Background
Currently, the most used augmentation rhinoplasty prosthesis in cosmetic surgery for augmentation rhinoplasty in the world and in china is a silicone rubber material prosthesis. The silicon rubber material is harmless to human body, has good biocompatibility, soft and firm texture and does not deteriorate for a long time. At present, clinically used prostheses of certain types are manufactured from the hump nose silicon rubber, the prostheses are packaged after being sterilized, then a doctor selects one prosthesis of the model close to the requirement according to the specific condition of each patient, the prosthesis is placed on an operating table after the aseptic packaging is opened, and then the prosthesis is carved according to the requirement of the patient and the experience of the doctor and is used for the operation.
The traditional silicon rubber nose prosthesis is widely applied clinically at present and has obvious operation effect. However, in the existing materials and technical methods, the operation effect cannot be predicted in advance, and is influenced by subjective factors such as experience of an operator, and the like, and postoperative complications are high, including: (1) the prosthesis is prone to shifting: before implantation, a doctor uses tissue forceps to separate an implantation chamber, the undersize does not meet the size requirement of an implanted prosthesis, and the oversize causes redundant space after the prosthesis is implanted, so that the prosthesis is easy to deflect after implantation; (2) unstable matching degree: the existing silica gel and the existing bulks are manually carved by doctors in the operation, the matching degree of the prosthesis and a patient has a direct relation with the carving technology of doctors, and the carving effect of the prosthesis is unstable; (3) exposing the silica gel prosthesis: because the texture of the silica gel prosthesis is hard and is manually carved by doctors, the prosthesis is uncomfortable in appearance, the texture of the tail end of the prosthesis is too hard, and two sides of the prosthesis are too sharp, so that the prosthesis is likely to be exposed; (4) the silica gel matching degree is not proper: the elastic moduli of different parts of the nose bridge are different, and the existing silica gel prostheses are all solid silica gel and cannot effectively adapt to the situation that the elastic moduli of different parts of the nose bridge are different; (5) the silica gel prosthesis is easy to contract the capsule: due to immune reaction, a layer of envelope can be formed on the surface of the silica gel prosthesis to trigger the contracture of the envelope; nasal deformity can be formed, which causes unnatural appearance after operation; (6) the silica gel prosthesis is easy to transmit light; after the silica gel prosthesis is implanted into a human body, the silica gel prosthesis is seen from the outside of the skin, and the light transmission phenomenon occurs, so that the postoperative effect is influenced; (7) the effect of the operation cannot be predicted before the operation: before operation, doctors and patients hope to visually see how the effect of the implanted prosthesis is, before operation, the prosthesis can be adjusted according to the requirements of the patients, but the traditional prosthesis cannot achieve the effect; (8) the operation effect cannot be objectivized and accurate: affected by subjective factors such as experience, aesthetic and carving techniques of surgeons, the difference of the operation effect of the surgeons with rich experience and beginners is larger, (9) material waste; the existing prosthesis is manufactured and used in a material reducing mode, and carving removal or laser printing removal is carried out in an operation, so that material waste is caused.
Disclosure of Invention
The purpose of the utility model is to solve the above-mentioned problem that prior art exists to a silica gel augmentation rhinoplasty is provided, solves the problem that above traditional silica gel prothesis faces, makes prothesis augmentation rhinoplasty operation effect predictable, individualized, accurate.
The technical solution of the utility model is that: the utility model provides a silica gel augmentation rhinoplasty, includes nose back part, nose point part and columella nasi part, nose point part is the form of buckling, nose back part and columella nasi part are connected respectively in the both ends of nose point part, nose back part, nose point part and columella nasi part are the three-dimensional network structure who is connected the formation by multilayer unit network structure, unit network structure piles up the formation by the parallel line group of multilayer, and whole silica gel augmentation rhinoplasty passes through 3D and prints integrated into one piece, and its whole is "L" shape.
Further, the above silica gel nose augmentation prosthesis, wherein: the raw material of the silica gel nose augmentation prosthesis is long-term implanted liquid silica gel.
Further, the above silica gel nose augmentation prosthesis, wherein: the porosity of the nasal back part is 5% -80%, the porosity of the nasal tip part is 20% -90%, and the porosity of the columella nasi part is 5% -80%.
Further, the above silica gel nose augmentation prosthesis, wherein: the aperture of the circle cut in the mesh of the unit mesh structure in the nasal back part is less than or equal to 1.5mm, the aperture of the circle cut in the mesh of the unit mesh structure in the nasal tip part is less than or equal to 2.0mm, and the aperture of the circle cut in the mesh of the unit mesh structure in the nasal columella part is less than or equal to 1.5 mm.
Still further, the above silicone augmentation rhinoplasty prosthesis, wherein: the thickness range of the unit reticular structure layer is 0.1-1.0 mm.
Still further, the above silicone augmentation rhinoplasty prosthesis, wherein: the nose back part is of an integrated structure.
Still further, the above silicone augmentation rhinoplasty prosthesis, wherein: the nose back part is of a double-layer structure with an inner layer and an outer layer, the porosity of the outer layer is 5% -80%, and the porosity of the inner layer is 0% -50%.
Still further, the above silica gel nose prosthesis, wherein: the thickness of the outer layer of the nose back part is 1-5mm, and the thickness of the inner layer is 2-6 mm.
Still further, the above silica gel nose prosthesis, wherein: the unit net structure is formed by stacking 2-6 layers of parallel line groups, parallel lines in each layer of parallel line group face different directions, parallel lines in each layer of parallel line group form a cross line structure in a plane view angle of a overlooking plane, and adjacent cross lines form an included angle of 30-90 degrees.
The utility model also discloses another kind of silica gel augmentation rhinoplasty false body, the three-dimensional network structure of silica gel augmentation rhinoplasty false body for connecting the formation by multilayer unit network structure, unit network structure piles up by the parallel group of multilayer and forms, and whole silica gel augmentation rhinoplasty false body is willow leaf shape, the porosity of silica gel augmentation rhinoplasty false body is 5% -80%.
The utility model discloses outstanding technological effect mainly embodies: (1) the design of the silica gel nose augmentation prosthesis in the utility model is customized by 3D printing according to human nose CT data, 3D photography and operation schemes, the matching with the nasal tissue is good, and the offset after the prosthesis is implanted is reduced; (2) in the manufacturing process of the silica gel nose augmentation prosthesis, doctors do not need to carve in the operation, thereby saving the operation time, reducing the material consumption and lightening the harm to patients; (3) the surface of the silica gel nose augmentation prosthesis is a porous rough surface, so that embedded growth of surrounding autologous tissues into the prosthesis can be realized, the formed position is stably fixed for a long time, the deformation quantity is smaller after the product is implanted into a human body, the postoperative accuracy is better predicted than that of a bulked prosthesis, the position slippage of the traditional silica gel nose prosthesis is prevented, the probability of capsular contracture is reduced due to the rough surface, in addition, the reflection path of light can be changed, the light transmittance is reduced, and the postoperative effect is improved; (4) the nose tip part is of a hole grid structure, so that the elasticity is better than that of the traditional silica gel nose prosthesis, and the probability of the prosthesis being exposed is reduced; (5) the nasal back is a structure with the interior tending to be solid, so that the area of an internal cavity is reduced compared with that of a bulge, the living space of bacteria is reduced, and the infection probability is reduced; (6) the silica gel nose augmentation prosthesis is provided with different apertures, fillings and layer thicknesses according to the elastic modulus of each section of the human nose bridge, so as to meet the requirements of the elastic modulus of different parts of the nose bridge.
Drawings
FIG. 1 is a left side view of an "L" shaped silicone carina prosthesis;
FIG. 2 is a top view of an "L" -shaped silicone carina prosthesis;
FIG. 3 is a front view of an "L" -shaped silicone carina prosthesis;
FIG. 4 is a schematic view of a willow-leaf-shaped silica gel hump nose prosthesis;
FIG. 5 is a top view of a mesh structure of a silicone hump nose prosthesis unit;
FIG. 6 is a schematic view of the net-like structure of the silica gel hump nose prosthesis unit;
FIG. 7 is a top view of another embodiment of a mesh structure of a silicone hump nose prosthesis unit;
fig. 8 is a method of using the silicone augmentation nasal prosthesis.
In the figures, the reference numerals have the meaning: 1-the dorsum of the nose part, 2-the tip of the nose part, and 3-the columella nasi part.
Detailed Description
The present invention will be described in further detail with reference to the following detailed description and accompanying drawings.
As shown in fig. 1 to 3, the silica gel nose augmentation prosthesis of the present invention includes a nose back portion 1, a nose tip portion 2 and a columella nasalis portion 3, the nose tip portion 2 is bent, the nose back portion 1 and the columella nasalis portion 3 are respectively connected to two ends of the nose tip portion 2, the nose back portion 1, the nose tip portion 2 and the columella nasalis portion 3 are all three-dimensional net structures, the three-dimensional net structures are formed by connecting multi-layer unit net structures, and the whole silica gel nose augmentation prosthesis is integrally formed by 3D printing, and the whole body is L-shaped.
Specifically, the porosity of the dorsum nasalis portion 1 is 5% to 80%, the porosity of the nose tip portion 2 is 20% to 90%, and the porosity of the columella nasi portion 3 is 5% to 80%. Silica gel is adopted as a material for 3D printing in the 3D printing process, and preferably, the raw material of the silica gel nose augmentation prosthesis is long-term implanted liquid silica gel. The back of the nose part 1, the nose tip part 2 and the columella nasi part 3 have different elastic moduli due to different porosities, so that the hardness of tissues suitable for different parts of the nose is formed, and specifically, the compression elastic modulus of the back of the nose part 1 is 1MPa-8 MPa; the modulus of elasticity in compression of the nose tip part 2 is 0.4MPa-7MPa, and the modulus of elasticity in compression of the columella nasi part 3 is 0.5MPa-8 MPa.
Preferably, the diameter of an inscribed circle of meshes of the unit mesh structure in the nasal back part 1 of the three-dimensional mesh structure is less than or equal to 1.5mm, the diameter of an inscribed circle of meshes of the unit mesh structure in the nasal tip part 2 is less than or equal to 2.0mm, and the diameter of an inscribed circle of meshes of the unit mesh structure in the columella nasi part 3 is less than or equal to 1.5 mm. The thickness range of the unit reticular structure layer is 0.1mm-1.0 mm. The nose back part 1 can be designed into an integral structure or an inner and outer double-layer structure, three-dimensional reticular structures of an inner layer and an outer layer in the nose back part 1 have different porosities, so that layering is formed, the porosity of the outer layer is 5% -80%, the porosity of the inner layer is 0% -50%, the thickness of the outer layer is 1-5mm, and the thickness of the inner layer is 2-6 mm. Silica gel itself has certain fluidity, and when the porosity reached a certain proportion, the inside closely knit degree of product can increase gradually, reaches complete solid structure even, thereby selects the silica gel and the porosity of suitable viscosity to guarantee the stability of external shape for nose back part inside tends to solid, the porous structure in surface, thereby forms different elastic modulus.
In addition, the dorsum of the nose part 1, the tip of the nose part 2 and the columella nasi part 3 can be designed into a multi-section structure, the dorsum of the nose part 1 is formed with two different porosities in the left and right direction, the two sections of bent parts of the tip of the nose part 2 are different in porosity, and the columella nasi part 3 is formed with two different porosities in the vertical direction, so that the dorsum of the nose part 1, the tip of the nose part 2 and the columella nasi part 3 form two sections of structures.
As shown in fig. 5 and 6, the unit mesh structure includes 3 layers of parallel lines, in fig. 6, the first, second and third layers of parallel lines constitute a first unit mesh structure, the fourth, fifth and sixth layers of parallel lines constitute a second unit mesh structure, and the first mesh structure is stacked on the second mesh unit. The unit net structure is composed of 3 layers of parallel line groups, one layer of parallel line group comprises a plurality of parallel lines, the parallel lines are connected to form a whole, the formed whole is the parallel line group, the directions of the parallel lines in different layers of parallel line groups are different, the 3 layers of parallel line groups are stacked in the vertical direction to form the unit net structure, the planes where the 3 layers of parallel line groups are located are mutually parallel, as shown in figure 5, the parallel lines in the 3 layers of parallel line groups form a cross line structure in the overlooking view angle of the planes, and the adjacent cross lines form an included angle of 60 degrees.
As shown in fig. 7, the unit net structure in fig. 7 is different from the unit net structures in fig. 5 and fig. 6 in that the unit net structure in fig. 7 is formed by stacking four layers of parallel line groups in the vertical direction, the planes of the four layers of parallel line groups are parallel to each other, the parallel lines in different layers of parallel line groups are oriented differently, the parallel lines in the four layers of parallel line groups form a cross line structure in the view of looking down on the plane, and the adjacent cross lines form an included angle of 45 degrees.
It should be noted that the schemes shown in fig. 5 to 7 are only preferred, and in practical use, the unit mesh structure may be designed to include 2 to 6 layers of parallel lines, the parallel lines in each layer of parallel lines are oriented differently, and the parallel lines in each layer of parallel lines are stacked in the vertical direction to form the unit mesh structure, the parallel lines in each layer of parallel lines form a cross line structure in the viewing angle of looking down the plane, and the adjacent cross lines form an included angle of 30 to 90 degrees. By adopting the unit net structure, the stress is better, the connection is more stable, and the elastic modulus can be controlled according to the distance between the parallel lines of the parallel line group.
It should be noted here that it is only preferable to set the silica gel nose-raising prosthesis in an "L" shape, and most of the silica gel nose-raising prostheses used at present are in an "L" shape or a willow leaf shape, and the whole silica gel nose-raising prosthesis can also be made into a willow leaf shape. As shown in fig. 4, the body of the silica gel nose prosthesis is a three-dimensional network structure formed by connecting a plurality of layers of network structures, the whole silica gel nose prosthesis is in a willow leaf shape, and the porosity of the silica gel nose prosthesis is 5-80%.
As shown in fig. 7, the manufacturing method and the using method of the present invention can be seen in the following two embodiments.
Example 1
1. Acquiring patient nose image data through medical imaging equipment such as CT, MRI, 3D photography and the like;
2. importing the acquired image data into special medical 3D modeling software, and establishing a 3D data model of the nose of the patient;
3. designing an operation scheme based on the obtained 3D data model of the nose of the patient, and designing a silica gel nose prosthesis;
4. the designed integral silica gel nasal prosthesis is designed in a segmented structure, according to the hardness of different parts of the bridge of the nose of a human body, the outer layer part of the nose back part 1 is designed to have 80% of porosity, the inner part of the nose back part 1 has 20% of porosity, the nose tip part 2 has 80% of porosity, and the columella nasi part 3 has 30% of porosity; the nose back part is of an inner-layer and outer-layer structure, the thickness of the outer-layer part is 2mm, and the thickness of the inner-layer part is 5mm;
5 as shown in fig. 5 and 6, the cross line units of the single-layer mesh structure of the silica gel hump nose prosthesis are designed to be in a 3-line cross shape, the adjacent cross lines form an included angle of 60 degrees, and the layer thickness of the unit mesh structure is 1.0 mm;
6. slicing the silica gel nose augmentation prosthesis layer by adopting slicing software to generate a file which can be identified by a 3D printer;
7. leading the generated 3D printing file of the silica gel nose prosthesis into a silica gel printer, and printing and manufacturing by adopting long-term implanted liquid silica gel as a raw material of the silica gel nose prosthesis;
8. cleaning the printed nasal prosthesis, packaging and sterilizing;
9. as shown in fig. 8, during surgery, the implantation chamber is established by tissue forceps
10. Then the silica gel nose prosthesis is implanted into the nose;
11. and (5) performing surgical suture to finish the operation.
Example 2
1. Acquiring patient nose image data through medical imaging equipment such as CT, MRI, 3D photography and the like;
2. importing the acquired image data into special medical 3D modeling software, and establishing a 3D data model of the nose of the patient;
3. designing an operation scheme based on the obtained 3D data model of the nose of the patient, and designing a silica gel nose prosthesis;
4. the designed integral silica gel nasal prosthesis is designed in a segmented structure, and according to the hardness of different parts of the bridge of the nose of a human body, the porosity of a nose back part 1 is designed to be 30%, the porosity of a nose tip part 2 is designed to be 60%, and the porosity of a columella nasi part 3 is designed to be 50%;
5. as shown in fig. 7, the cross line units of the unit network structure of the silica gel hump nose prosthesis are designed to be in a cross-like shape like a Chinese character mi formed by four lines, the adjacent cross lines form an included angle of 45 degrees, and the thickness of the layer of the unit network structure is 0.5mm;
6. slicing the silica gel nose prosthesis layer by adopting slicing software to generate a file which can be identified by a 3D printer;
7. leading the generated 3D printing file of the silica gel nose prosthesis into a silica gel printer, and printing and manufacturing by adopting long-term implanted liquid silica gel as a raw material of the silica gel nose prosthesis;
8. cleaning the printed silica gel nasal prosthesis, packaging and sterilizing;
9. as shown in FIG. 8, during surgery, after the nasal incision is established, the implantation chamber is established by tissue forceps;
10. then the nasal prosthesis is implanted into the nose;
11. and (5) performing surgical suture to finish the operation.
Example 3
1. Acquiring patient nose image data through medical imaging equipment such as CT, MRI, 3D photography and the like;
2. importing the acquired image data into special medical 3D modeling software, and establishing a 3D data model of the nose of the patient;
3. designing an operation scheme based on the obtained 3D data model of the nose of the patient, and designing a silica gel nose prosthesis;
4. the designed silica gel nose prosthesis is integrally designed in a segmented structure, and according to the hardness of different parts of the nose bridge of a human body, the outer layer part of the nose back part 1 is designed to have 40% of porosity, the inner part of the nose back part 1 has 10% of porosity, the nose tip part 2 has 40% of porosity, and the columella nasi part 3 has 40% of porosity; the nose back part is of an inner-layer and outer-layer structure, the thickness of the outer-layer part is 3mm, and the thickness of the inner-layer part is 4 mm;
5 as shown in fig. 5 and 6, the cross line units of the single-layer mesh structure of the silica gel nasal prosthesis are designed to be in a 3-line cross shape, the adjacent cross lines form an included angle of 60 degrees, and the layer thickness of the unit mesh structure is 0.3 mm;
6. slicing the silica gel nose prosthesis layer by adopting slicing software to generate a file which can be identified by a 3D printer;
7. importing the generated 3D printing file of the nasal prosthesis into a silica gel printer, and printing and manufacturing by adopting long-term implantation type liquid silica gel as a raw material of the nasal prosthesis;
8. cleaning the printed silica gel nasal prosthesis, packaging and sterilizing;
9. as shown in fig. 8, during surgery, the implantation chamber is established by tissue forceps
10. Then the nasal prosthesis is implanted into the nose;
11. and (5) performing surgical suture to finish the operation.
As can be seen from the above description, the utility model has the following advantages that (1) the design of the silica gel nose augmentation prosthesis is customized by 3D printing according to the CT data of human nose, 3D photography, patient requirements and operation scheme, the post-operation effect can be displayed by three-dimensional imaging, and the operation effect can be predicted in advance; the prosthesis is printed, so that the operation effect is more objective and accurate, and the influence of subjective factors such as the experience of an operator is avoided; the matching with nasal tissues is good, and the offset of the implanted prosthesis is reduced; (2) in the manufacturing process of the silica gel nose augmentation prosthesis, doctors do not need to carve in the operation, thereby saving the operation time, reducing the material consumption and lightening the harm to patients; (3) the surface of the silica gel nose augmentation prosthesis is a porous rough surface, so that embedded growth of surrounding autologous tissues into the prosthesis can be realized, the formed position is stably fixed for a long time, the deformation quantity is smaller after the product is implanted into a human body, the postoperative accuracy is better predicted than that of a bulked prosthesis, the position slippage of the traditional silica gel nose prosthesis is prevented, the probability of capsular contracture is reduced due to the rough surface, in addition, the reflection path of light can be changed, the light transmittance is reduced, and the postoperative effect is improved; (4) the nose tip part is of a hole grid structure, so that the elasticity is better than that of the traditional silica gel nose prosthesis, and the probability of the prosthesis being exposed is reduced; (5) the nasal back is a structure with the interior tending to be solid, so that the area of an internal cavity is reduced compared with that of a bulge, the living space of bacteria is reduced, and the infection probability is reduced; (6) the silica gel nose augmentation prosthesis is provided with different apertures, fillings and layer thicknesses according to the elastic modulus of each section of the human nose bridge, so as to meet the requirements of the elastic modulus of different parts of the nose bridge.
Of course, the above is only a typical example of the present invention, and besides, the present invention can also have other various specific embodiments, and all technical solutions adopting equivalent replacement or equivalent transformation are all within the scope of the present invention as claimed.
Claims (10)
1. A silica gel nose augmentation prosthesis is characterized in that: including nose back of the body part, nose point part and columella nasi part, nose point part is the form of buckling, nose back of the body part and columella nasi part are connected respectively in the both ends of nose point part, nose back of the body part, nose point part and columella nasi part are the three-dimensional network structure who is connected the formation by multilayer unit network structure, unit network structure piles up the formation by the parallel group of multilayer, and whole silica gel hump nose false body prints integrated into one piece through silica gel 3D, and its whole is "L" shape.
2. The silicone augmentation rhinoplasty prosthesis of claim 1, wherein: the raw material of the silica gel nose augmentation prosthesis is long-term implantation type liquid silicone rubber.
3. The silicone augmentation rhinoplasty prosthesis of claim 1, wherein: the porosity of the nasal back part is 5% -80%, the porosity of the nasal tip part is 20% -90%, and the porosity of the columella nasi part is 5% -80%.
4. The silicone augmentation rhinoplasty prosthesis of claim 1, wherein: the aperture of the circle cut in the mesh of the unit mesh structure in the nasal back part is less than or equal to 1.5mm, the aperture of the circle cut in the mesh of the unit mesh structure in the nasal tip part is less than or equal to 2.0mm, and the aperture of the circle cut in the mesh of the unit mesh structure in the nasal columella part is less than or equal to 1.5 mm.
5. The silicone augmentation rhinoplasty prosthesis of claim 1, wherein: the thickness range of the unit reticular structure layer is 0.1-1.0 mm.
6. The silicone augmentation rhinoplasty prosthesis of claim 1, wherein: the nose back part is of an integrated structure.
7. The silicone augmentation rhinoplasty prosthesis of claim 1, wherein: the nose back part is of a double-layer structure with an inner layer and an outer layer, the porosity of the outer layer is 5% -80%, and the porosity of the inner layer is 0% -50%.
8. The silicone augmentation rhinoplasty prosthesis of claim 7, wherein: the thickness of the outer layer of the nose back part is 1-5mm, and the thickness of the inner layer is 2-6 mm.
9. The silicone augmentation rhinoplasty prosthesis of claim 1, wherein: the unit net structure is formed by stacking 2-6 layers of parallel line groups, parallel lines in each layer of parallel line group face different directions, parallel lines in each layer of parallel line group form a cross line structure in a plane view angle of a overlooking plane, and adjacent cross lines form an included angle of 30-90 degrees.
10. A silica gel nose augmentation prosthesis is characterized in that: the body of the silica gel nose augmentation prosthesis is a three-dimensional reticular structure formed by connecting a plurality of layers of unit reticular structures, the unit reticular structure is formed by stacking a plurality of layers of parallel lines, the whole silica gel nose augmentation prosthesis is in a willow leaf shape, and the porosity of the silica gel nose augmentation prosthesis is 5% -80%.
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| CN109998735A (en) * | 2019-01-25 | 2019-07-12 | 宁波创导三维医疗科技有限公司 | Silica gel nose augmentation prosthesis and its manufacturing method |
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| CN109998735A (en) * | 2019-01-25 | 2019-07-12 | 宁波创导三维医疗科技有限公司 | Silica gel nose augmentation prosthesis and its manufacturing method |
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