CN210665633U - 一种多维在线高效液相色谱装置 - Google Patents
一种多维在线高效液相色谱装置 Download PDFInfo
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- CN210665633U CN210665633U CN201921171638.6U CN201921171638U CN210665633U CN 210665633 U CN210665633 U CN 210665633U CN 201921171638 U CN201921171638 U CN 201921171638U CN 210665633 U CN210665633 U CN 210665633U
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- 238000004128 high performance liquid chromatography Methods 0.000 title claims abstract description 24
- 238000000605 extraction Methods 0.000 claims abstract description 82
- 238000000926 separation method Methods 0.000 claims abstract description 35
- 239000007788 liquid Substances 0.000 claims abstract description 33
- 238000004458 analytical method Methods 0.000 claims abstract description 32
- 238000000746 purification Methods 0.000 claims abstract description 23
- 238000004587 chromatography analysis Methods 0.000 claims abstract description 17
- 238000002414 normal-phase solid-phase extraction Methods 0.000 claims abstract description 17
- 238000004811 liquid chromatography Methods 0.000 claims abstract description 16
- 238000005070 sampling Methods 0.000 claims abstract description 10
- 238000001514 detection method Methods 0.000 claims abstract description 9
- 238000003795 desorption Methods 0.000 claims description 13
- 238000002347 injection Methods 0.000 claims description 6
- 239000007924 injection Substances 0.000 claims description 6
- 239000002699 waste material Substances 0.000 claims description 6
- 239000002904 solvent Substances 0.000 claims description 5
- 238000010828 elution Methods 0.000 claims description 3
- 238000000034 method Methods 0.000 abstract description 8
- 239000008280 blood Substances 0.000 abstract description 3
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- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 12
- 238000005516 engineering process Methods 0.000 description 5
- 238000004780 2D liquid chromatography Methods 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 238000013375 chromatographic separation Methods 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000008363 phosphate buffer Substances 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- ABFPKTQEQNICFT-UHFFFAOYSA-M 2-chloro-1-methylpyridin-1-ium;iodide Chemical compound [I-].C[N+]1=CC=CC=C1Cl ABFPKTQEQNICFT-UHFFFAOYSA-M 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
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- 239000011159 matrix material Substances 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
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- 229960005197 quetiapine fumarate Drugs 0.000 description 2
- 238000011160 research Methods 0.000 description 2
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- 239000013076 target substance Substances 0.000 description 2
- 230000004913 activation Effects 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
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- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
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- 229940079593 drug Drugs 0.000 description 1
- 239000003480 eluent Substances 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
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- -1 purify Substances 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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Application Number | Priority Date | Filing Date | Title |
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CN201921171638.6U CN210665633U (zh) | 2019-07-24 | 2019-07-24 | 一种多维在线高效液相色谱装置 |
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CN201921171638.6U CN210665633U (zh) | 2019-07-24 | 2019-07-24 | 一种多维在线高效液相色谱装置 |
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Date | Code | Title | Description |
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GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20231215 Address after: 210000, Building 6, No. 18 Zhilan Road, Jiangning District, Nanjing City, Jiangsu Province, China, 108-46 (Jiangning High tech Park) Patentee after: Nanjing Aidimai Technology Co.,Ltd. Address before: Room 105-17, No. 10 Jinshan Road, High tech Zone, Suzhou City, Jiangsu Province, 215000 Patentee before: Suzhou aidimai Medical Technology Co.,Ltd. |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of utility model: A multidimensional online high-performance liquid chromatography device Granted publication date: 20200602 Pledgee: Bank of Nanjing Co.,Ltd. Jiangning sub branch Pledgor: Nanjing Aidimai Technology Co.,Ltd. Registration number: Y2024980008518 |