CN210631584U

CN210631584U - Multi-instrument synchronous stimulation system

Info

Publication number: CN210631584U
Application number: CN201920760765.3U
Authority: CN
Inventors: 曹乐; 徐逸帆; 魏德轩; 黄经纬; 陆彦希; 刘乐远
Original assignee: Shanghai University of Engineering Science
Current assignee: Shanghai University of Engineering Science
Priority date: 2019-05-24
Filing date: 2019-05-24
Publication date: 2020-05-29
Anticipated expiration: 2029-05-24

Abstract

The utility model discloses a multi-instrument synchronous stimulation system, which comprises a single chip microcomputer and at least two stimulators, wherein each stimulator comprises a signal output module, each signal output module comprises an output terminal, a pull-down resistor and a TVS (transient voltage suppressor) tube, the pull-down resistor of each signal output module and one end of the TVS tube which are connected in parallel are connected with the same I/O (input/output) port of the single chip microcomputer, one end of each pull-down resistor which is connected in parallel is also connected with the corresponding output terminal, and the other ends of the pull-down resistors which are connected in parallel with the TVS tube are grounded; the output terminals of two adjacent stimulators are connected, and the output terminals are used for respectively outputting and inputting signals to the two adjacent stimulators. The utility model provides a fixed main and slave computer does not exist to many stimulators, and optional arbitrary stimulator can control a plurality of stimulators and start simultaneously and stop as the host computer to one of them stimulator fault during the stop work, can not influence other stimulators and normally work.

Description

Multi-instrument synchronous stimulation system

Technical Field

The utility model relates to a biological synchronous stimulator field, in particular to a synchronous amazing system of many instruments for biostimulation.

Background

With the development of scientific technology, more and more experimental instruments are applied to physiological and pharmacological experiments to deepen the understanding of natural life. The physiological electrical stimulator is a device capable of applying electrical stimulation to biological tissues, and is used for applying stimulation to a study object or tissues to cause physiological changes of the study object or tissues, so as to study the study object or tissues. The electric stimulator is in an important position in the field of physiological and pharmacological experiments, for example, the incidence of neurological diseases is increased increasingly with the increase of the pressure of modern society, and an electric stimulation convulsion experiment is an important method for establishing an animal depression model; when animal behavior research experiments are carried out, an electric signal is used for stimulating a certain part of an animal, and the functional state of the part can be identified according to the reflection made by the animal.

Parameters such as stimulation waveform, stimulation intensity and stimulation time output by the biological stimulator have different physiological influences on organisms or tissues in the same state. For example, different electrical stimulation waveforms have great influence on directional arrangement of adipose-derived mesenchymal stem cells; the stimulation frequency has obvious influence on the biological state, the stimulation frequency can be used for treating biological tissues when the stimulation frequency is very low, and the stimulation frequency is more than a critical value, so that the biological tissues are damaged and even die.

The animal comparison experiment mode is a common experiment mode in the evaluation of the physiological and pharmacological potency. Because of the limitation of stimulators in the market, when contrast experiments are carried out at present, after stimulation parameters are set, independent experiments are respectively carried out on experimental objects, and the stimulation mode is low in efficiency and low in accuracy. In a multi-instrument synchronous stimulation scheme, the trigger delay time of the existing synchronous trigger control method in the wireless network is longer than that of pure hardware, and possible factors of signal instability are increased due to a Wifi network. When synchronous control stimulation is carried out on stimulators in the market, a fixed main stimulator is required, once the main stimulator breaks down, synchronous stimulation of multiple instruments cannot be realized, and inconvenience is brought to normal use.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a synchronous amazing system of many instruments to not enough among the prior art to solve above-mentioned problem.

The utility model provides a technical problem can adopt following technical scheme to realize:

a multi-instrument synchronous stimulation system comprises a single chip microcomputer and at least two stimulators, wherein each stimulator comprises a signal output module, each signal output module comprises an output terminal, a pull-down resistor and a TVS (transient voltage suppressor) which are arranged in parallel, one end of each pull-down resistor of each signal output module, which is connected with the TVS, in parallel, is connected with the same I/O (input/output) port of the single chip microcomputer, one end of each pull-down resistor, which is connected with the corresponding output terminal, in parallel, and the other end of each pull-down resistor, which is connected with the TVS, in; the output terminals of two adjacent stimulators are connected, and the output terminals are used for respectively outputting and inputting signals to the two adjacent stimulators.

Furthermore, the number of the stimulators is 4, the output terminals are 4-port wiring terminals, one end of each pull-down resistor of each signal output module, which is connected with the TVS tube in parallel, is connected with the No. 1 end and the No. 3 end of the corresponding output terminal, and the No. 2 end and the No. 4 end of each output terminal are grounded; the No. 3 end of the output terminal of the 1 st stimulator is connected with the No. 1 end of the output terminal of the 2 nd stimulator, and the No. 4 end of the output terminal of the 1 st stimulator is connected with the No. 2 end of the output terminal of the 2 nd stimulator; the No. 3 end of the output terminal of the No. 2 stimulator is connected with the No. 1 end of the output terminal of the No. 3 stimulator, and the No. 4 end of the output terminal of the No. 2 stimulator is connected with the No. 2 end of the output terminal of the No. 3 stimulator; no. 3 end of the output terminal of the 3 rd stimulator is connected with No. 1 end of the output terminal of the 4 th stimulator, and No. 4 end of the output terminal of the 3 rd stimulator is connected with No. 2 end of the output terminal of the 4 th stimulator.

Furthermore, the I/O ports corresponding to the stimulators are all in an external interrupt mode, and the I/O ports corresponding to all the stimulators are connected in parallel and are in a synchronous input mode.

Furthermore, the interruption of the stimulator adopts an external interruption 3 mode of LPC1768, the model of the singlechip is LPC1768, and an I/O port of the signal output module, which is connected with the singlechip, is P2.13.

Furthermore, the signal output modules of the stimulator are connected through a DuPont wire.

Compared with the prior art, the beneficial effects of the utility model are as follows:

the utility model provides a synchronous scheme of biostimulator can realize the synchronous amazing of many instruments, reaches amazing time synchronization's effect through hardware parallel connection. When carrying out contrast experiment, need not stimulate the biology one by one, but stimulate simultaneously, improved biological assay's efficiency, guaranteed the accuracy nature of experiment, can be arranged in contrast experiment or other needs in the biological physiology pharmacology experiment adopt synchronous electro photoluminescence ware research field.

When a plurality of instruments are synchronously stimulated, the utility model has no fixed host and slave machines, and can choose one stimulator as the main stimulator of the proposal; the DuPont wire is used for connecting the output terminal of the signal output module in each stimulator, so that compared with the wireless connection, the trigger time is shorter, the synchronization accuracy is high, the signal is more stable and is not easily interfered; when the stimulator works in the multi-stimulation mode, if one stimulator fails, the normal work of the rest stimulators cannot be influenced.

Drawings

Fig. 1 is a schematic diagram of the overall operation of a multi-instrument synchronous stimulation mode.

Fig. 2 is a schematic structural diagram of the signal output module according to the present invention.

Fig. 3 is a diagram showing a synchronous stimulation connection mode in the case of 4 stimulators.

Fig. 4 is a pin diagram of the single chip microcomputer according to the present invention.

Fig. 5 is a flow chart illustrating the use of the multi-instrument simultaneous stimulation system of the present invention.

Detailed Description

In order to make the technical means, creation features, achievement purposes and functions of the present invention easy to understand, the present invention is further described below with reference to the following embodiments.

Referring to fig. 1 to 5, the multi-instrument synchronous stimulation system of the present invention includes a single chip and at least two stimulators. The stimulator comprises a signal output module, wherein the signal output module comprises an output terminal, a pull-down resistor and a TVS (transient voltage suppression diode) which are arranged in parallel. The pull-down resistor of each signal output module is connected with one end of the TVS tube in parallel and is connected with the same I/O port of the single chip microcomputer, and the end connected in parallel is also connected with the corresponding output terminal. The other ends of the pull-down resistors and the TVS tubes which are connected in parallel are all grounded. The output terminals of two adjacent stimulators are connected, and the output terminals are used for respectively outputting and inputting signals to the two adjacent stimulators.

The biostimulator can realize synchronous stimulation of a plurality of instruments, does not have a fixed host and a slave machine when the synchronous stimulation of the plurality of instruments, can select an optional stimulator as a main stimulator, and does not have a fixed main stimulator. Each stimulator is grounded, parallel hardware connection is carried out by adopting a single wire, external interruption is adopted, ultra-low time delay is adopted, signals are stable, and the stimulators are not easy to interfere. When a plurality of stimulators are used for synchronous stimulation, if one stimulator fails and does not work, the normal work of other stimulators cannot be influenced.

Take a synchronous stimulation scheme of 4 stimulators as an example, that is, there are 4 stimulators, and the output terminal is a 4-port connection terminal. One end of the pull-down resistor of each signal output module, which is connected with the TVS tube in parallel, is connected with the No. 1 end and the No. 3 end of the corresponding output terminal, and the input sides of the No. 2 end and the No. 4 end of the output terminal are grounded. The terminal 3 of the output terminal P5 of the 1 st stimulator is connected to the terminal 1 of the output terminal P6 of the 2 nd stimulator, and the terminal 4 of the output terminal P5 of the 1 st stimulator is connected to the terminal 2 of the output terminal P6 of the 2 nd stimulator. The No. 3 terminal of the output terminal P6 of the 2 nd stimulator is connected to the No. 1 terminal of the output terminal P7 of the 3 rd stimulator, and the No. 4 terminal of the output terminal P6 of the 2 nd stimulator is connected to the No. 2 terminal of the output terminal P7 of the 3 rd stimulator. The terminal 3 of the output terminal P7 of the 3 rd stimulator is connected to the terminal 1 of the output terminal P8 of the 4 th stimulator, and the terminal 4 of the output terminal P7 of the 3 rd stimulator is connected to the terminal 2 of the output terminal P8 of the 4 th stimulator. Of course, the number of stimulators for the multi-instrument simultaneous stimulation protocol is at least two and is not limited to the 4 mentioned above. And connecting the two adjacent output terminals by analogy according to the connection mode, namely when n stimulators exist, connecting the end 3 of the output terminal of the 1 st stimulator with the end 1 of the output terminal of the 2 nd stimulator, connecting the end 4 of the output terminal of the 1 st stimulator with the end 2 of the output terminal of the 2 nd stimulator until the end 3 of the output terminal of the n-1 st stimulator is connected with the end 1 of the output terminal of the n th stimulator, and connecting the end 4 of the output terminal of the n-1 st stimulator with the end 2 of the output terminal of the n th stimulator.

The I/O ports corresponding to the stimulators are all in an external interrupt mode, and the I/O ports corresponding to all the stimulators are connected in parallel and are in a synchronous input mode.

The signal output modules of the stimulator are connected through a DuPont wire. The DuPont wire is used for connecting the signal output module of each stimulator, so that the synchronous accuracy is improved in a shorter time compared with the wireless connection, the signals are more stable, and the signals are not easily interfered.

The utility model discloses during the use, after the control module of biostimulator received the amazing parameter instruction that the host computer sent, produced amazing by amazing module, when carrying out many stimulator synchronous working, carried out signal transmission by the signal output interface: the signal output protection module consists of a pull-down resistor and an output terminal, wherein the TVS tube can prevent the singlechip LPC1768 from being damaged by transient pulse and carry out electrostatic protection; the pull-down resistor is grounded, and the TVS tube ensures that the I/O port keeps a low level state when no input is input. The output terminal adopts a 4-port wiring terminal, can respectively carry out signal output and signal input on two adjacent stimulators, and achieves the common-ground effect.

The utility model provides a synchronous amazing scheme design of many instruments for biostimulation can be used to contrast experiment among the physiology pharmacology experiment and other electro photoluminescence experiments that need fixed stimulation parameter, and concrete step is as follows:

under the premise that each device can work independently and normally, the I/O ports corresponding to all stimulators are connected in parallel, all the I/O ports are set to be in an input mode, a synchronous input mode is selected, and the I/O port corresponding to each stimulator is set to be in a rising edge external interrupt mode;

when the switch is operated, the corresponding I/O port is set to an I/O output mode and a high level is output, and the stimulator becomes a main stimulator at the time. And the rest other stimulators carry out rising edge detection, and when the rising edge input is detected, the other stimulators generate interruption, namely when a rising edge signal is detected, an interruption function is called to generate an external interruption response, and the output of the stimulators is controlled to realize synchronous stimulation.

The interruption of the stimulator adopts an external interruption 3 mode of LPC1768, the model of the singlechip is LPC1768, and the I/O port of the signal output module, which is correspondingly connected with the singlechip, is P2.13.

The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. A multi-instrument simultaneous stimulation system, characterized by: the stimulator comprises a single chip microcomputer and at least two stimulators, wherein each stimulator comprises a signal output module, each signal output module comprises an output terminal, a pull-down resistor and a TVS (transient voltage suppressor) tube which are arranged in parallel, one end of each pull-down resistor of each signal output module, which is connected with the TVS tube in parallel, is connected with the same I/O (input/output) port of the single chip microcomputer, one end of each pull-down resistor, which is connected with the TVS tube in parallel, is also connected with the corresponding output terminal, and the other end of each pull-; the output terminals of two adjacent stimulators are connected, and the output terminals are used for respectively outputting and inputting signals to the two adjacent stimulators.

2. The multi-instrument simultaneous stimulation system according to claim 1, characterized in that: the number of the stimulators is 4, the output terminals are 4-port wiring terminals, one end of each signal output module, which is connected with the TVS tube in parallel, is connected with the No. 1 end and the No. 3 end of the corresponding output terminal, and the No. 2 end and the No. 4 end of each output terminal are grounded; the No. 3 end of the output terminal of the 1 st stimulator is connected with the No. 1 end of the output terminal of the 2 nd stimulator, and the No. 4 end of the output terminal of the 1 st stimulator is connected with the No. 2 end of the output terminal of the 2 nd stimulator; the No. 3 end of the output terminal of the No. 2 stimulator is connected with the No. 1 end of the output terminal of the No. 3 stimulator, and the No. 4 end of the output terminal of the No. 2 stimulator is connected with the No. 2 end of the output terminal of the No. 3 stimulator; no. 3 end of the output terminal of the 3 rd stimulator is connected with No. 1 end of the output terminal of the 4 th stimulator, and No. 4 end of the output terminal of the 3 rd stimulator is connected with No. 2 end of the output terminal of the 4 th stimulator.

3. The multi-instrument simultaneous stimulation system according to claim 1, characterized in that: the I/O ports corresponding to the stimulators are all in an external interrupt mode, and the I/O ports corresponding to all the stimulators are connected in parallel and are in a synchronous input mode.

4. The multi-instrument simultaneous stimulation system of claim 3, wherein: the interruption of the stimulator adopts an LPC1768 external interruption 3 mode, the model of the single chip microcomputer is LPC1768, and an I/O port, connected with the single chip microcomputer, of the signal output module is P2.13.

5. The multi-instrument simultaneous stimulation system according to claim 1, characterized in that: and the signal output modules of the stimulator are connected through a DuPont wire.