CN210626498U

CN210626498U - Biochemical combined reagent plate suitable for rapid detection

Info

Publication number: CN210626498U
Application number: CN201921661806.XU
Authority: CN
Inventors: 涂奠基; 张立群; 刘飞; 蒋栋能
Original assignee: Second Affiliated Hospital Army Medical University
Current assignee: Second Affiliated Hospital Army Medical University
Priority date: 2019-09-30
Filing date: 2019-09-30
Publication date: 2020-05-26
Anticipated expiration: 2029-09-30

Abstract

The utility model belongs to the technical field of medical equipment, and relates to a biochemical combined reagent disc suitable for rapid detection, which comprises a disc-shaped reagent disc, positioning holes arranged on the reagent disc, and a second channel and a third channel which are respectively arranged on two opposite sides of the reagent disc and have the same radian as the reagent disc, wherein the outer side of the second channel is respectively communicated with a reaction tank through the fourth channel, the third channel is respectively communicated with a contrast tank through the fourth channel, exhaust holes are respectively communicated on the second channel and the third channel, a sample adding pool with exhaust holes and a blank adding pool are respectively arranged on the inner sides of the second channel and the third channel, a second sample adding hole and a first sample adding hole are respectively communicated on the sample adding pool and the blank adding pool, the sample adding pool and the second channel are communicated through an arc-shaped first channel, so that the biochemical reagent disc in the prior art can not be freely combined to detect a plurality of biochemical items, and the detection result can not be obtained quickly and accurately.

Description

Biochemical combined reagent plate suitable for rapid detection

Technical Field

The utility model belongs to the technical field of medical instrument, a biochemical combination reagent dish suitable for short-term test is related to.

Background

POCT, point-of-care testing, refers to clinical testing and bedside testing performed near a patient, and is not always performed by a clinical laboratory technician. The method is a new method for analyzing the sample immediately on the sampling site, saving complex processing procedures of the sample during laboratory test and quickly obtaining test results.

The existing blood detection usually needs to take blood samples and then carry out detection in a laboratory, the blood detection is mainly completed by a clinical laboratory through a large instrument, the detection flow of the clinical laboratory is relatively complex, the blood is easy to deteriorate in the transportation process, a patient usually cannot take a detection result immediately, the patient needs to be operated immediately in an emergency, a doctor cannot take a result report immediately to carry out clinical judgment, and the optimal operation time is easy to miss.

In addition, the existing biochemical reagent plate can not freely combine biochemical detection items, so that various detection data of each patient can not be quickly obtained, and the use is very inconvenient.

SUMMERY OF THE UTILITY MODEL

In view of this, the utility model provides a biochemical combination reagent dish suitable for short-term test for the problem that solves biochemical reagent dish among the prior art can not independent assortment detect a plurality of biochemical projects to can not obtain the testing result fast, accurately.

In order to achieve the above object, the utility model provides a biochemical combination reagent dish suitable for short-term test, including discoid reagent dish, set up the locating hole on the reagent dish and set up respectively in the relative both sides of reagent dish and with second passageway and the third passageway that the reagent dish radian is the same, the second passageway outside has the reaction cell through fourth passageway intercommunication respectively, the third passageway has the contrast pond through fourth passageway intercommunication respectively, it has the exhaust hole to communicate respectively on second passageway and the third passageway, second passageway and third passageway inboard set up respectively the intercommunication have sample application of sample pond and the blank application of sample pond of taking the exhaust hole, it has second application of sample hole and first application of sample hole to communicate respectively on sample application pond and the blank application of sample pond, communicate through curved first passageway between sample application of sample pond and the second passageway.

The beneficial effect of this basic scheme lies in: the positioning hole on the reagent tray is used for positioning the reagent tray, and the reagent tray is conveniently positioned after the centrifugation of the reagent tray is stopped, so that the position of the reagent tray in the centrifuge can be determined. The blank sample adding pool is used for placing buffer solution for detecting reference, the sample adding pool is used for placing buffer solution required by detection, and under the centrifugal force of the centrifugal machine, the buffer solution respectively enters the second channel and the third channel, and then respectively enters the reaction pool and the comparison pool to react with corresponding reagents. The sample adding pool is communicated with the second channel through the arc-shaped first channel, so that when the centrifuge moves, liquid in the reaction pool flows back to the sample adding pool.

Furthermore, the number of the comparison pools outside the third channel is 4, the included angle between the adjacent comparison pools is 16 degrees, the number of the reaction pools outside the second channel is 8, and the included angle between the adjacent reaction pools is 16 degrees. Has the advantages that: the included angle between the adjacent comparison pool and the adjacent reaction pool is the same, so that the detection data is more accurate. Meanwhile, the number of the comparison pools is 4, the number of the reaction pools is 8, and multiple detections can be simultaneously carried out.

Further, reagent dish radius is 40 ~ 45mm, and thickness is 5mm, and the one end that blank application of sample pond and sample application of sample pond were kept away from to first application of sample hole and second application of sample hole is circular-arc and the arc segment is the downward sloping form, and first application of sample hole and second application of sample hole width are 2mm, and the arc segment degree of depth is 2mm, and the slope length of arc segment is 3 mm. Has the advantages that: the arc sections of the two sample adding holes are both downward inclined, so that the blood can be conveniently added.

Further, the width of the sample adding pool and the width of the blank adding pool are both 7mm, the depth of the sample adding pool is 5mm, the length of the sample adding pool is 2 times of that of the blank adding pool, the width of the second channel and the width of the third channel are both 1.5mm, and the depth of the second channel and the depth of the third channel are both 1.1 mm.

Furthermore, the width and the depth of the first channel are both 0.5mm, the width of the fourth channel is both 1.5mm, and the depth of the fourth channel is both 0.8 mm.

Furthermore, the diameter of the positioning hole is 6mm, the diameter of the exhaust hole is 2.2mm, and the diameters of the reaction tank and the comparison tank are both 4 mm.

The beneficial effects of the utility model reside in that:

1. the utility model discloses a biochemical combination reagent dish suitable for short-term test can be in 8 reaction tanks of reagent dish required detection items of independent assortment, realizes the quick inspection of different detection items. For example, a biochemical item for detecting peripheral blood can be added into the sample adding hole, so that the detection method for clinically extracting venous blood can be changed. The reagent tray can complete the detection of all items within 15 minutes.

2. The utility model discloses a biochemical combination reagent dish suitable for short-term test can realize swift bedside inspection, and is automatic, miniaturized, and multi-functional independent assortment detects biochemical project. In order to meet the requirement of emergency treatment under field conditions, the reagent disk can realize the rapid, simple, convenient and accurate implementation of medical examination in a battlefield, and has important significance for battlefield first aid.

Additional advantages, objects, and features of the invention will be set forth in part in the description which follows and in part will become apparent to those having ordinary skill in the art upon examination of the following or may be learned from practice of the invention. The objectives and other advantages of the invention may be realized and attained by the means of the instrumentalities and/or combinations particularly pointed out in the appended claims.

Drawings

For the purposes of promoting a better understanding of the objects, features and advantages of the invention, reference will now be made to the following detailed description taken in conjunction with the accompanying drawings in which:

fig. 1 is a schematic structural diagram of the biochemical combined reagent disk suitable for rapid detection of the present invention.

Reference numerals: positioning hole 1, vent hole 2, sample application pool 3, blank application pool 4, first channel 5, second channel 6, third channel 7, fourth channel 8, first application hole 9, second application hole 10, reaction pool 11, contrast pool 12.

Detailed Description

The following description of the embodiments of the present invention is provided for illustrative purposes, and other advantages and effects of the present invention will be readily apparent to those skilled in the art from the disclosure herein. The present invention can also be implemented or applied through other different specific embodiments, and various details in the present specification can be modified or changed based on different viewpoints and applications without departing from the spirit of the present invention. It should be noted that the drawings provided in the following embodiments are only for illustrating the basic idea of the present invention, and the features in the following embodiments and examples may be combined with each other without conflict.

Wherein the showings are for the purpose of illustrating the invention only and not for the purpose of limiting the same, and in which there is shown by way of illustration only and not in any way limiting the scope of the invention; for a better understanding of the embodiments of the present invention, some parts of the drawings may be omitted, enlarged or reduced, and do not represent the size of an actual product; it will be understood by those skilled in the art that certain well-known structures in the drawings and descriptions thereof may be omitted.

The same or similar reference numerals in the drawings of the embodiments of the present invention correspond to the same or similar parts; in the description of the present invention, it should be understood that if there are terms such as "upper", "lower", "left", "right", "front", "back", etc., indicating directions or positional relationships based on the directions or positional relationships shown in the drawings, it is only for convenience of description and simplification of description, but it is not intended to indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore, the terms describing the positional relationships in the drawings are only used for illustrative purposes and are not to be construed as limiting the present invention, and those skilled in the art can understand the specific meanings of the terms according to specific situations.

Fig. 1 shows a biochemical combined reagent disk suitable for rapid detection, which includes a disk-shaped reagent disk, positioning holes 1 disposed on the reagent disk, and a second channel 6 and a third channel 7 disposed on opposite sides of the reagent disk and having the same radian as the reagent disk, wherein the outer sides of the second channel 6 are respectively communicated with a reaction cell 11 through a fourth channel 8, the third channel 7 is respectively communicated with a contrast cell 12 through the fourth channel 8, the second channel 6 and the third channel 7 are respectively communicated with an exhaust hole 2, the inner sides of the second channel 6 and the third channel 7 are respectively provided with a sample adding cell 3 and a blank adding cell 4 which are communicated with the exhaust hole 2, the sample adding cell 3 and the blank adding cell 4 are respectively communicated with a second sample adding hole 10 and a first sample adding hole 9, and the sample adding cell 3 and the second channel 6 are communicated with each other through an arc-shaped first channel 5.

The number of the comparison pools 12 outside the third channel 7 is 4, the included angle between the adjacent comparison pools 12 is 16 degrees, the number of the reaction pools 11 outside the second channel 6 is 8, and the included angle between the adjacent reaction pools 11 is 16 degrees. The included angles between the adjacent comparison cells 12 and the adjacent reaction cells 11 are the same, so that the detection data can be more accurate. Meanwhile, the number of the comparison pools is 4, the number of the reaction pools is 8, and multiple detections can be simultaneously carried out. The radius of the reagent plate is 40-45 mm, the thickness is 5mm, one end of the first sample adding hole 9 and the second sample adding hole 10 far away from the blank sample adding pool 4 and the sample adding pool 3 is arc-shaped and arc-shaped, the width of the first sample adding hole 9 and the width of the second sample adding hole 10 are 2mm, the depth of the arc-shaped is 2mm, and the slope length of the arc-shaped is 3 mm. The arc sections of the two sample adding holes are both downward inclined, so that the blood can be conveniently added. The width of the sample adding pool 3 and the width of the blank adding pool 4 are both 7mm, the depth of the sample adding pool is 5mm, the length of the sample adding pool 3 is 2 times of that of the blank adding pool 4, the width of the second channel 6 and the width of the third channel 7 are both 1.5mm, and the depth of the second channel and the depth of the third channel are both 1.1 mm. The width and depth of the first channel 5 are both 0.5mm, the width of the fourth channel 8 is both 1.5mm, and the depth is both 0.8 mm. The diameter of the positioning hole 1 is 6mm, the diameter of the exhaust hole 2 is 2.2mm, and the diameters of the reaction tank 11 and the comparison tank 12 are both 4 mm.

When the biochemical combined reagent disk is used, firstly organic glass with the thickness of 1mm and high smoothness is stuck on the bottom surface of the processed reagent disk, and a through hole 1 is formed in the center positioning hole. Be used for fixing a position the reagent dish through locating hole 1 on the reagent dish, conveniently fix a position the reagent dish after the reagent dish centrifugation stops to confirm the position of reagent dish in centrifuge. Adding a buffer solution for detection reference into a blank sample adding pool 4, adding a buffer solution required for detection into a sample adding pool 3, adding 10ml of peripheral blood into the sample adding pools corresponding to a first sample adding hole 9 and a second sample adding hole 10, filling dry powder ball reagents required for biochemical project detection in free combination into 8 reaction pools 11, and under the centrifugal force of a centrifugal machine, respectively allowing the buffer solution with blood to enter a second channel 6 and a third channel 7 through corresponding channels, and further respectively entering the reaction pools 11 and a comparison pool 12 to react with the corresponding reagents. The detection result is obtained by comparing the color development result of the blood in the reaction tank 11 with the color development result of the blood in the comparison tank 12.

Finally, the above embodiments are only used for illustrating the technical solutions of the present invention and not for limiting, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that modifications or equivalent substitutions may be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions, and all of them should be covered by the scope of the claims of the present invention.

Claims

1. The biochemical combined reagent disc is characterized by comprising a disc-shaped reagent disc, positioning holes arranged on the reagent disc, a second channel and a third channel which are respectively arranged on two opposite sides of the reagent disc and have the same radian as the reagent disc, wherein the outer side of the second channel is communicated with a reaction tank through the fourth channel, the third channel is communicated with a contrast tank through the fourth channel, the second channel and the third channel are respectively communicated with exhaust holes, the inner sides of the second channel and the third channel are respectively communicated with a sample adding tank with exhaust holes and a blank sample adding tank, the sample adding tank and the blank sample adding tank are respectively communicated with a second sample adding hole and a first sample adding hole, and the sample adding tank and the second channel are communicated through an arc-shaped first channel.

2. The biochemical combined reagent disk suitable for rapid detection according to claim 1, wherein the number of the contrast pools outside the third channel is 4, the included angle between the adjacent contrast pools is 16 °, the number of the reaction pools outside the second channel is 8, and the included angle between the adjacent reaction pools is 16 °.

3. The biochemical combined reagent disk suitable for rapid detection according to claim 2, wherein the radius of the reagent disk is 40-45 mm, the thickness is 5mm, the ends of the first and second sample adding holes far away from the blank sample adding pool and the sample adding pool are arc-shaped, the arc segment is inclined downwards, the width of the first and second sample adding holes is 2mm, the depth of the arc segment is 2mm, and the slope length of the arc segment is 3 mm.

4. The biochemical combined reagent disk suitable for rapid detection according to claim 2, wherein the width of each of the sample loading cell and the blank loading cell is 7mm, the depth of each of the sample loading cell and the blank loading cell is 5mm, the length of the sample loading cell is 2 times that of the blank loading cell, the width of each of the second channel and the third channel is 1.5mm, and the depth of each of the second channel and the third channel is 1.1 mm.

5. The biochemical combination reagent tray suitable for rapid detection according to claim 2, wherein the width and depth of the first channel are both 0.5mm, the width of the fourth channel is both 1.5mm, and the depth is both 0.8 mm.

6. The biochemical combination reagent disk suitable for rapid detection according to claim 2, wherein the diameter of the positioning hole is 6mm, the diameter of the vent hole is 2.2mm, and the diameters of the reaction cell and the comparison cell are both 4 mm.