CN210604533U - Fixing device for liquid chromatographic analysis of chiral drugs - Google Patents
Fixing device for liquid chromatographic analysis of chiral drugs Download PDFInfo
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- CN210604533U CN210604533U CN201921297339.7U CN201921297339U CN210604533U CN 210604533 U CN210604533 U CN 210604533U CN 201921297339 U CN201921297339 U CN 201921297339U CN 210604533 U CN210604533 U CN 210604533U
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Abstract
The utility model relates to the technical field of chiral drug detection equipment, in particular to a fixing device for liquid chromatography analysis of chiral drugs, which comprises a base, a rotary platform and a fixing base which are arranged from bottom to top in sequence, wherein the base is rotationally connected with the bottom surface of the rotary platform through a bearing; this fixing device for liquid chromatography of chiral medicine is through the detection groove that is equipped with, be convenient for place the chiral medicine of liquid form, traditional fixed mode has been changed, the fixing device who is equipped with simultaneously, be convenient for form the protection to detecting the groove through solid fixed ring and lens, prevent that the foreign matter from getting into, in addition, through the setting of check lock lever and a plurality of detection groove, make a plurality of experiment specimens of user of service once only preparation, and can detect the groove rotation to the eyepiece down with the difference through rotating rotary platform, and is comparatively convenient, the problem of the liquid chromatography of chiral medicine is not convenient for to carry out to current fixed mode is solved.
Description
Technical Field
The utility model relates to a chirality medicine check out test set technical field specifically is a fixing device for liquid chromatography of chirality medicine.
Background
Chiral drugs, which are a pair of enantiomers that are physical and mirror images of each other and obtained after introducing a chiral center into the molecular structure of a drug, and liquid chromatography is a chromatographic analysis method using liquid as a mobile phase; when carrying out liquid chromatographic analysis, current chiral medicine adopts liquid chromatographic analyzer to analyze it more, traditional test mode is between placing two glass lenses with the liquid medicine and is placed under liquid chromatographic analyzer's observation eyepiece, on the one hand, this fixed mode easily causes the liquid medicine to leak from between two glass, thereby it is troublesome to bring unnecessary clearance, and the liquid medicine of seepage also easily causes the damage to liquid chromatographic analyzer, on the other hand, when testing a plurality of experimental bodies (the liquid medicine of chiral medicine) simultaneously, need separately carry out the preparation and the inspection of experimental body, comparatively inconvenient, in view of this, we propose a fixing device for liquid chromatographic analysis of chiral medicine.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a fixing device for liquid chromatography of chiral medicine to solve the current fixed mode that provides in the above-mentioned background art and be not convenient for carry out the problem that liquid chromatography was carried out to chiral medicine.
In order to achieve the above object, the utility model provides a following technical scheme:
a fixing device for liquid chromatography analysis of chiral drugs comprises a base, a rotary platform and a fixing seat which are sequentially arranged from bottom to top, wherein the base is rotationally connected with the bottom surface of the rotary platform through a bearing; the top surface of the rotating platform is provided with a plurality of detection grooves at equal intervals in an annular shape near the edge, and the center of the top surface of the rotating platform is provided with a thread groove; a plurality of chutes are annularly and equidistantly formed in the position, close to the bottom end, of the circumferential outer wall of the fixed seat, a plurality of through holes are annularly and equidistantly formed in the position, close to the edge, of the top surface of the fixed seat, and a round hole is formed in the center of the top surface of the fixed seat; a plurality of fixing devices are annularly and equidistantly arranged on the fixing seat, each fixing device comprises a connecting rod, the top end of each connecting rod penetrates through the through hole, the bottom end of each connecting rod is located in the corresponding sliding groove, a pull ring is arranged at the top end of each connecting rod, a sliding block is arranged at the bottom end of each connecting rod and is in sliding connection with the corresponding sliding groove, a spring is further arranged in each sliding groove, the spring is sleeved on each connecting rod, a supporting rod is arranged on one side face of each sliding block, a fixing ring is arranged at the end part of each supporting rod, and a lens is embedded in each fixing ring; the locking device is characterized in that a locking rod is arranged in the round hole and comprises a threaded rod and a fine adjustment screw coaxially arranged at the top end of the threaded rod, the threaded rod penetrates through the round hole, and the threaded rod is in threaded connection with the threaded groove.
Preferably, the overall shape of the sliding groove and the sliding block is trapezoidal.
Preferably, one of the fixing rings is located right above the corresponding detection groove.
Preferably, the bottom end of the threaded rod extends onto the base.
Preferably, the overall shape of the base is trapezoidal.
Preferably, the number of said fixing means is 5 to 7.
Preferably, one of the through holes is communicated with the corresponding sliding groove.
Compared with the prior art, the beneficial effects of the utility model are that: this fixing device for liquid chromatography of chiral medicine is through the detection groove that is equipped with, be convenient for place the chiral medicine of liquid form, traditional fixed mode has been changed, the fixing device who is equipped with simultaneously, be convenient for form the protection to detecting the groove through solid fixed ring and lens, prevent that the foreign matter from getting into, in addition, through the setting of check lock lever and a plurality of detection groove, make a plurality of experiment specimens of user of service once only preparation, and can detect the groove rotation to the eyepiece down with the difference through rotating rotary platform, and is comparatively convenient, the problem of the liquid chromatography of chiral medicine is not convenient for to carry out to current fixed mode is solved.
Drawings
Fig. 1 is one of the overall structural diagrams of the present invention;
fig. 2 is a second schematic view of the overall structure of the present invention;
FIG. 3 is a schematic structural view of a rotating platform according to the present invention;
FIG. 4 is a schematic structural view of the fixing base of the present invention;
FIG. 5 is a schematic view of an exploded structure of the fixing base of the present invention;
fig. 6 is a schematic structural view of the middle fixing device of the present invention.
In the figure: 1. a base; 2. rotating the platform; 21. a detection tank; 22. a thread groove; 3. a fixed seat; 31. a chute; 32. a through hole; 33. a circular hole; 4. a fixing device; 41. a connecting rod; 42. a pull ring; 43. a slider; 44. a spring; 45. a strut; 46. a fixing ring; 461. a lens; 5. a locking lever; 51. a threaded rod; 52. the helix is fine tuned.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and to simplify the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically limited otherwise.
Example 1
A fixing device for liquid chromatography analysis of chiral drugs is shown in figures 1 to 4 and comprises a base 1, a rotary platform 2 and a fixing seat 3 which are sequentially arranged from bottom to top, wherein the base 3 is tightly adhered to the rotary platform 2, and the bottom surfaces of the base 1 and the rotary platform 2 are rotationally connected through a bearing; a plurality of detection grooves 21 are annularly and equidistantly formed in the top surface of the rotary platform 2 close to the edge, and a thread groove 22 is formed in the center of the top surface of the rotary platform 2; the circumference outer wall of fixing base 3 is close to bottom department and is annular equidistant a plurality of spouts 31 have been seted up, and the top surface of fixing base 3 is close to the edge and is annular equidistant a plurality of through-holes 32 have been seted up, and round hole 33 has been seted up to the top surface center department of fixing base 3.
In this embodiment, the overall shape of the base 1 is trapezoidal, and the trapezoidal base 1 has better stability.
In the present embodiment, one through hole 32 communicates with the corresponding slide slot 31, which facilitates the movement of the link 41.
Referring to fig. 6, a plurality of fixing devices 4 are arranged on the fixing base 3 at equal intervals in an annular shape, each fixing device 4 includes a connecting rod 41, the top end of each connecting rod 41 penetrates through the through hole 32, the bottom end of each connecting rod 41 is located in the corresponding sliding groove 31, each pull ring 42 is arranged at the top end of each connecting rod 41, each slider 43 is arranged at the bottom end of each connecting rod 41, two ends of each connecting rod 41 are respectively and tightly bonded with the corresponding pull ring 42 and the corresponding slider 43, each slider 43 is in sliding connection with the corresponding sliding groove 31, each sliding groove 31 is further internally provided with a spring 44, each spring 44 is sleeved on each connecting rod 41, a supporting rod 45 is arranged on one side face of each slider 43, a fixing ring 46 is arranged at the.
In this embodiment, the overall shape of the sliding slot 31 and the sliding block 43 is trapezoidal, and the trapezoidal sliding slot 31 provides a limiting function for the sliding block 43, so that the sliding block 43 can slide along the sliding slot 31 conveniently.
In the present embodiment, a fixing ring 46 is located right above the corresponding detecting slot 21, which facilitates the fixing ring 46 to drive the lens 461 to cover the detecting slot 21, thereby preventing the entry of foreign objects during the detecting process.
In this embodiment, the number of the fixing devices 4 is 5 to 7, and the preferable number of the fixing devices 4 is 6, which can detect 6 chiral drug test bodies at one time, thereby improving the detection efficiency.
Referring to fig. 5, a locking rod 5 is arranged in the circular hole 33, the locking rod 5 comprises a threaded rod 51 and a fine adjustment screw 52 coaxially arranged at the top end of the threaded rod 51, the threaded rod 51 passes through the circular hole 33, and the threaded rod 51 is in threaded connection with the threaded groove 22.
In this embodiment, the bottom of threaded rod 51 extends to on the base 1, and when screwing up threaded rod 51, the bottom of threaded rod 51 supports tightly on base 1, and base 1 can not rotate this moment, plays limiting displacement promptly to revolving platform 22 to be convenient for detect the interior chiral medicine of groove 21.
When the fixing device for liquid chromatography analysis of chiral drugs in the embodiment is used, a user firstly pulls the pull ring 42 upwards, the connecting rod 41 slides in the through hole 32 at the moment, the sliding block 43 slides upwards in the sliding groove 31, the spring 44 is compressed, the supporting rod 45 and the fixing ring 46 synchronously move upwards, the user places the chiral drugs to be detected into the detection groove 21, then releases the pull ring 42, the spring 44 resets and drives the fixing ring 46 and the lens 461 to cover the detection groove 21, then the user places one of the detection grooves 21 under an ocular lens of a liquid chromatograph analyzer, and finally the detection is performed through the liquid chromatograph analyzer;
when one detects groove 21 and detects finishing, user unscrews check lock lever 5, and user of service rotates rotary platform 2 simultaneously to make adjacent detection groove 21 move under the eyepiece of liquid chromatography appearance, can detect once more.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It should be understood by those skilled in the art that the present invention is not limited by the above embodiments, and the description in the above embodiments and the description is only preferred examples of the present invention, and is not intended to limit the present invention, and that the present invention can have various changes and modifications without departing from the spirit and scope of the present invention, and these changes and modifications all fall into the scope of the claimed invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (7)
1. The utility model provides a fixing device for liquid chromatography of chiral drugs, includes base (1), rotary platform (2) and fixing base (3) that supreme being equipped with in proper order down, its characterized in that: the base (1) is rotatably connected with the bottom surface of the rotating platform (2) through a bearing; a plurality of detection grooves (21) are annularly and equidistantly formed in the top surface of the rotary platform (2) close to the edge, and a thread groove (22) is formed in the center of the top surface of the rotary platform (2); a plurality of sliding grooves (31) are formed in the position, close to the bottom end, of the outer wall of the circumference of the fixed seat (3) at equal intervals in an annular mode, a plurality of through holes (32) are formed in the position, close to the edge, of the top surface of the fixed seat (3) at equal intervals in an annular mode, and a round hole (33) is formed in the center of the top surface of the fixed seat (3); a plurality of fixing devices (4) are annularly and equidistantly arranged on the fixing seat (3), each fixing device (4) comprises a connecting rod (41), the top end of each connecting rod (41) penetrates through the corresponding through hole (32), the bottom end of each connecting rod (41) is located in the corresponding sliding groove (31), a pull ring (42) is arranged at the top end of each connecting rod (41), a sliding block (43) is arranged at the bottom end of each connecting rod (41), the sliding block (43) is connected with the corresponding sliding groove (31) in a sliding mode, a spring (44) is further arranged in each sliding groove (31), the spring (44) is sleeved on the corresponding connecting rod (41), a supporting rod (45) is arranged on one side face of each sliding block (43), a fixing ring (46) is arranged at the end portion of each supporting rod (45), and a lens (461) is embedded in; be equipped with check lock lever (5) in round hole (33), check lock lever (5) are including fine setting spiral (52) of the coaxial setting in top of threaded rod (51) and threaded rod (51), threaded rod (51) are passed round hole (33), just threaded rod (51) with thread groove (22) threaded connection.
2. The fixing device for liquid chromatography analysis of a chiral drug according to claim 1, characterized in that: the overall shape of the sliding groove (31) and the sliding block (43) is trapezoidal.
3. The fixing device for liquid chromatography analysis of a chiral drug according to claim 1, characterized in that: one of the fixing rings (46) is located directly above the corresponding detection groove (21).
4. The fixing device for liquid chromatography analysis of a chiral drug according to claim 1, characterized in that: the bottom end of the threaded rod (51) extends to the base (1).
5. The fixing device for liquid chromatography analysis of a chiral drug according to claim 1, characterized in that: the overall shape of the base (1) is trapezoidal.
6. The fixing device for liquid chromatography analysis of a chiral drug according to claim 1, characterized in that: the number of the fixing devices (4) is 5 to 7.
7. The fixing device for liquid chromatography analysis of a chiral drug according to claim 1, characterized in that: one through hole (32) is communicated with the corresponding sliding groove (31).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921297339.7U CN210604533U (en) | 2019-08-12 | 2019-08-12 | Fixing device for liquid chromatographic analysis of chiral drugs |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921297339.7U CN210604533U (en) | 2019-08-12 | 2019-08-12 | Fixing device for liquid chromatographic analysis of chiral drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN210604533U true CN210604533U (en) | 2020-05-22 |
Family
ID=70715986
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201921297339.7U Active CN210604533U (en) | 2019-08-12 | 2019-08-12 | Fixing device for liquid chromatographic analysis of chiral drugs |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN210604533U (en) |
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2019
- 2019-08-12 CN CN201921297339.7U patent/CN210604533U/en active Active
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