CN210596093U

CN210596093U - Culture device

Info

Publication number: CN210596093U
Application number: CN201920981381.4U
Authority: CN
Inventors: 魏云鹏; 商澎; 王·迪凯; 韩炜
Original assignee: Shenzhen Institute of Northwestern Polytechnical University
Current assignee: Shenzhen Institute of Northwestern Polytechnical University
Priority date: 2019-06-26
Filing date: 2019-06-26
Publication date: 2020-05-22
Anticipated expiration: 2029-06-26

Abstract

The utility model is suitable for a biological cultivation technical field provides a culture apparatus. The utility model discloses a culture apparatus, which comprises a housin, and locate the inside limited subassembly of casing, limited subassembly includes a plurality of limiters of following the circumferencial direction and arranging in proper order, a plurality of limiters enclose to close and form the storage tank, hold in the storage tank and be used for bearing the carrier of culture, the limiters are the permanent magnet, when placing the cell on bearing the carrier, the cell is located the magnetic field region between a plurality of permanent magnets, place this culture apparatus in the incubator, can realize external culture cell in the magnetic field, relative to prior art's technical scheme, the cost is lower, can reduce the shared space of experiment, the economic benefits has been improved greatly.

Description

Culture device

Technical Field

The utility model relates to a biological cultivation technical field, in particular to culture device.

Background

With the progress of human science and technology, the magnet has more and more extensive applications, including the fields of electromechanical technology, communication technology and the like. In the field of biomedical technology, the application of magnets is not very widespread, and the effects of magnetic fields on normal living individuals, tissues and cells, and on diseased individuals, pathological tissues and harmful cells are very interesting research hotspots and are currently being studied intensively.

In studying the biological effect of magnetic field on cells, the cells must be grown in a corresponding cell culture vessel, then the vessel is placed in a magnetic field environment, and finally the effect of magnetic field exposure on the life activities of the cells is observed. However, the existing operation of placing cells in a culture dish for culture, placing the culture dish with the cells in an incubator capable of simulating the growth environment in the living body, and then placing the incubator in a room provided with a magnetic field requires a large space, which undoubtedly results in an increase in research cost.

Disclosure of Invention

An object of the utility model is to provide a culture apparatus aims at solving the higher technical problem of cost that the external culture cell of body exposes to the sun magnetism.

The utility model discloses a realize like this, a culture apparatus, including the casing, and locate the inside limited subassembly of casing, it includes a plurality of limiters that arrange in proper order along the circumferencial direction, and is a plurality of the limiters enclose to close and form the storage tank, hold in the storage tank and be used for bearing the carrier that bears the culture, the limiters is the permanent magnet.

Further, the limiting piece is tile-shaped.

Furthermore, one side of the limiting piece, which is far away from the accommodating groove, is defined as a first side edge, one side of the limiting piece, which is close to the accommodating groove, is defined as a second side edge, and the first side edge and the second side edge are both arc-shaped.

Further, the arc length of the first side edge is greater than the arc length of the second side edge.

Further, a plurality of the limiting pieces are all magnetized in the radial direction.

Furthermore, the magnetizing directions of the limiting piece are all the directions that the middle point of the first side faces to the central axis of the containing groove.

Further, the bearing piece is an iron core, and the surfaces of the two ends of the bearing piece are exposure areas.

Furthermore, the limiting assembly comprises 2N limiting pieces, the 1 st limiting piece and the (N + 1) th limiting piece are both magnetized in the radial direction, the A th limiting piece and the B th limiting piece are both magnetized in the circumferential direction, wherein N is an integer larger than 2, A and B are integers, A is larger than or equal to 2 and is smaller than or equal to N, and N +2 is larger than or equal to B and is smaller than or equal to 2N.

Furthermore, the magnetizing direction of the 1 st limiting piece is the direction from the midpoint of the first side edge to the midpoint of the second side edge, the magnetizing direction of the (N + 1) th limiting piece is the direction from the midpoint of the second side edge to the midpoint of the first side edge, the magnetizing direction of the 1 st limiting piece, the magnetizing direction of the A th limiting piece and the magnetizing direction of the (N + 1) th limiting piece form a first magnetizing loop, the magnetizing direction of the 1 st limiting piece, the magnetizing direction of the B th limiting piece and the magnetizing direction of the (N + 1) th limiting piece form a second magnetizing loop, and the directions of the first magnetizing loop and the second magnetizing loop are opposite.

Further, the bearing part is a plastic cylinder with a cavity, and the cavity is an exposure area.

The utility model provides a culture device, which comprises a housin, and locate the inside limited subassembly of casing, limited subassembly includes a plurality of limiters of following the circumferencial direction and arranging in proper order, a plurality of limiters enclose to close and form the storage tank, hold in the storage tank and be used for bearing the carrier of culture, the limiters are the permanent magnet, when placing the cell on bearing the carrier, the cell is located the magnetic field region between a plurality of permanent magnets, place this culture device in the incubator, can realize external culture cell in the magnetic field, compared with the technical scheme of prior art, the cost is lower, can reduce the shared space of experiment, the economic benefits has been improved greatly.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for the embodiments or the prior art descriptions will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.

FIG. 1 is a schematic perspective view of a culture apparatus according to a first embodiment of the present invention;

FIG. 2 is a schematic view showing an exploded structure of a culture apparatus according to a first embodiment of the present invention;

FIG. 3 is a schematic view showing the direction of magnetization of a culture apparatus according to a first embodiment of the present invention;

FIG. 4 is a graph showing a magnetic field intensity simulation of a culture apparatus according to a first embodiment of the present invention;

FIG. 5 is a schematic perspective view of a culture apparatus according to a second embodiment of the present invention;

FIG. 6 is a schematic view showing an exploded structure of a culture apparatus according to a second embodiment of the present invention;

FIG. 7 is a schematic view showing the direction of magnetization of a culture apparatus according to a second embodiment of the present invention;

FIGS. 8 and 9 are graphs showing the simulation of the magnetic field intensity of a culture apparatus according to a second embodiment of the present invention.

Wherein, in the figures, the respective reference numerals:

21-a housing; 22-a defining component;

221-a restriction member; 23-a carrier.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the invention.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly or indirectly secured to the other element. When an element is referred to as being "connected to" another element, it can be directly or indirectly connected to the other element. The terms "upper", "lower", "left", "right", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description, but do not indicate or imply that the referred devices or elements must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the patent. The terms "first", "second" and "first" are used merely for descriptive purposes and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features. The meaning of "plurality" is two or more unless specifically limited otherwise.

In order to explain the technical solution of the present invention, the following detailed description is made with reference to the specific drawings and examples.

Example one

Referring to fig. 1 and 2, a first embodiment of the present invention provides a culture apparatus, including a housing 21 and a limiting component 22 disposed inside the housing 21, wherein the limiting component 22 includes a plurality of limiting members 221 sequentially arranged along a circumferential direction, the limiting members 221 surround to form a containing cavity, a carrying member 23 for carrying a culture is accommodated in the containing cavity, the limiting members 221 are permanent magnets, wherein the culture includes but is not limited to animal and plant cells, plant tissues, plant seeds, microorganisms (bacteria, viruses, fungi, etc.) and insects (fruit flies, etc.), and the embodiments of the present invention take the cells as an example for illustration. In this embodiment, the casing 21 is an aluminum alloy product, and the shape thereof may be a cylinder, and according to the selection of the actual situation, the casing 21 may be made of other non-magnetic materials, and the shape thereof may also be modified appropriately, which is not limited herein.

The utility model discloses culture apparatus, including casing 21, and locate casing 21 inside inject subassembly 22, inject subassembly 22 including a plurality of limiters 221 along circumferencial direction adjacent arrangement in proper order, a plurality of limiters 221 enclose to close and form the storage tank, hold in the storage tank and be used for bearing the carrier 23 of culture, limiters 221 is the permanent magnet, when placing the cell on carrier 23, the cell is located the magnetic field region between a plurality of permanent magnets, place this culture apparatus in the incubator, can realize the external culture cell in magnetic field, compared with the technical scheme of prior art, the cost is lower, can reduce the shared space of experiment, economic benefits has been improved greatly.

Specifically, the limiting member 221 is tile-shaped, a side of the limiting member 221 away from the accommodating groove is defined as a first side, a side of the limiting member 221 close to the accommodating groove is defined as a second side, and both the first side and the second side are arc-shaped.

Further, the arc length of the limiting members 221 gradually decreases from the first side edge to the direction close to the second side edge, and the side surfaces of the adjacent limiting members 221 are tightly connected.

It should be noted that, as shown in fig. 3 and 4, in the culture apparatus of the present embodiment, the plurality of the limiting members 221 are all magnetized in radial direction. Specifically, as shown in fig. 1 to 3, the arrows in the drawings are magnetization directions, the numbers 1 to 12 respectively refer to the 1 st to 12 th limiting members 221, the limiting assembly 22 includes 12 limiting members 221, and the magnetization direction of each limiting member 221 is the direction that the midpoint of the first side faces the central axis of the accommodating groove, i.e., the direction is magnetized centripetally, so that the magnetic field strength in the accommodating groove is strongest, when the cells are placed on the bearing member 23, the experimental operation complexity of in vitro culture cell exposure is greatly simplified, and the cell exposure scale and efficiency in the magnetic biology research are improved. It is understood that the number of the limiting members 221 can be modified as appropriate according to the actual situation, as long as the number of the limiting members 221 is more than one.

It should be noted that, for further improving magnetic field intensity, the bearing member 23 may be configured as an iron core, and the iron core can realize a magnetism gathering effect, so that the magnetism of the end surfaces at the two ends of the iron core is strongest, that is, the surfaces at the two ends of the bearing member 23 are the exposure areas corresponding to the culture, and a user may directly place cells on the end surfaces of the iron core, or place a culture dish in which the cells are placed on the end surfaces of the iron core. It is understood that the bearing member 23 may be a rod-shaped member made of other magnetic conductive materials, and the embodiment is not limited thereto.

Example two

Referring to fig. 5 to 9, a second embodiment of the present invention provides a culture device, which is different from the first embodiment in that: the limiting component 22 comprises 2N limiting pieces 221, the 1 st limiting piece 221 and the (N + 1) th limiting piece 221 are all magnetized in radial direction, the A limiting piece 221 and the B limiting piece 221 are all magnetized in circumferential direction, wherein N is an integer larger than 2, A and B are integers, A is larger than or equal to 2 and is smaller than or equal to N, and N +2 is larger than or equal to B and is smaller than or equal to 2N. The culture device of the embodiment has low cost, can reduce the space occupied by the experiment, and greatly improves the economic benefit.

Specifically, the magnetizing direction of the 1 st limiting member 221 is a direction from the midpoint of the first side edge to the midpoint of the second side edge, the magnetizing direction of the (N + 1) th limiting member 221 is a direction from the midpoint of the second side edge to the midpoint of the first side edge, the magnetizing direction of the 1 st limiting member 221, the magnetizing direction of the a th limiting member 221 and the magnetizing direction of the (N + 1) th limiting member 221 form a first magnetizing loop, the magnetizing direction of the 1 st limiting member 221, the magnetizing direction of the B th limiting member 221 and the magnetizing direction of the (N + 1) th limiting member 221 form a second magnetizing loop, and the directions of the first magnetizing loop and the second magnetizing loop are opposite. In this embodiment, the limiting component 22 has a loop-type magnetizing direction, so that a magnetic loop can be formed inside the limiting component, leakage of magnetic flux is less, and normal operation of other surrounding electrical appliances is not affected, and the magnetic field direction in the accommodating groove is the direction from the midpoint of the second side edge of the 1 st limiting piece 221 toward the central axis of the accommodating groove.

For convenience of description, as shown in fig. 7 to 9, the present embodiment is described by taking the limiting assembly 22 including 12 limiting members 221 as an example, the arrows in the figure are the magnetizing directions, the numbers 1 to 12 refer to the 1 st to 12 th limiting members 221 respectively, in this embodiment, N is equal to 6, the magnetization direction of the 1 st limiting member 221 is a direction from the midpoint of the first side toward the midpoint of the second side, the magnetization direction of the 7 th limiting member 221 is a direction from the midpoint of the second side toward the midpoint of the first side, a first magnetization loop in a clockwise direction is formed from the magnetization direction of the 1 st limiting member 221 to the magnetization direction of the 7 th limiting member 221, the magnetization direction of the 1 st limiting member 221, the magnetization directions of the 8 th to 12 th limiting members 221, and the magnetization direction of the 7 th limiting member 221 form a second magnetization loop in a counterclockwise direction, and the directions of the first magnetization loop and the second magnetization loop are opposite.

It should be noted that, in order to ensure that the magnetic field direction in the accommodating groove is a parallel magnetic field, the bearing member 23 may be a plastic cylinder member having a cavity, the cavity and a region right above the cavity are exposure regions corresponding to the culture, and the magnetic field of the exposure regions is a parallel magnetic field from the midpoint of the second side of the 1 st limiting member 221 toward the direction close to the central axis of the accommodating groove. The region right above the cavity refers to the upper region of the cavity corresponding to the axial direction. It is understood that the bearing member 23 may be made of other non-magnetic materials according to the practical application, and the embodiment is not limited herein.

It is worth mentioning that, in this embodiment, the magnetic field strength of the exposure area decreases gradually from the center of the cavity to the two ends of the plastic cylinder, the decreasing gradient of the magnetic field strength inside the corresponding cavity is smaller than the decreasing gradient of the magnetic field strength in the area right above the corresponding cavity, by setting the plastic cylinders with different heights, the culture can be set at different magnetic field strength heights, and the user can culture cells in the environment with the appropriate magnetic field strength by selecting the plastic cylinders with different heights.

The above description is only an alternative embodiment of the present invention, and should not be construed as limiting the present invention, and any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The culture device is characterized by comprising a shell and a limiting assembly arranged in the shell, wherein the limiting assembly comprises a plurality of limiting pieces which are sequentially arranged along the circumferential direction, the limiting pieces surround to form a containing groove, a bearing piece for bearing a culture is contained in the containing groove, and the limiting pieces are permanent magnets.

2. The culture device of claim 1, wherein the restriction member is tile-shaped.

3. The culture device of claim 1, wherein the side of the limiting member away from the containing groove is defined as a first side, the side of the limiting member close to the containing groove is defined as a second side, and the first side and the second side are both circular arcs.

4. The culture device of claim 3, wherein the arc length of the first side is greater than the arc length of the second side.

5. The culture device of claim 3, wherein a plurality of the restriction members are radially magnetized.

6. The culture device of claim 5, wherein the magnetizing direction of the limiting member is a direction in which the midpoint of the first side faces toward the central axis of the containing groove.

7. The culture device according to claim 6, wherein the carrier is a ferrite core, and surfaces of both ends of the carrier are exposed magnetic regions.

8. The culture device of claim 3, wherein the limiting component comprises 2N limiting members, the 1 st limiting member and the (N + 1) th limiting member are magnetized in radial direction, the A-th limiting member and the B-th limiting member are magnetized in circumferential direction, wherein N is an integer greater than 2, A and B are integers, and 2. ltoreq. A.ltoreq.N, and N + 2. ltoreq. B.ltoreq.2N.

9. The culture device according to claim 8, wherein the magnetization direction of the 1 st restriction member is a direction from the midpoint of the first side toward the midpoint of the second side, the magnetization direction of the N +1 th restriction member is a direction from the midpoint of the second side toward the midpoint of the first side, the magnetization direction of the 1 st restriction member, the magnetization direction of the A-th restriction member and the magnetization direction of the N +1 th restriction member form a first magnetization loop, the magnetization direction of the 1 st restriction member, the magnetization direction of the B-th restriction member and the magnetization direction of the N +1 th restriction member form a second magnetization loop, and the first magnetization loop is opposite to the second magnetization loop.

10. The culture device of claim 9, wherein the carrier is a plastic cylinder having a cavity, the cavity being an exposed magnetic region.