CN210481391U - Real-time imaging device applied to rotation system - Google Patents
Real-time imaging device applied to rotation system Download PDFInfo
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- CN210481391U CN210481391U CN201920851683.XU CN201920851683U CN210481391U CN 210481391 U CN210481391 U CN 210481391U CN 201920851683 U CN201920851683 U CN 201920851683U CN 210481391 U CN210481391 U CN 210481391U
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Abstract
The utility model discloses a be applied to real-time image device of rotating system, including the rotatory frame of rectangle, camera frame, first spout support and second spout support. The utility model discloses can be used to help the researcher research to explore when the cell is cultivateed in the microgravity effect of gyration system simulation, real-time transmission and record cell image, the experimenter of being convenient for control cell growth state and acquire more experimental information. The imaging device is adaptive to different types and different sizes of cell cultivators, can accurately adjust the camera to the imaging view field range by adjusting the sliding groove support, and enables the lens to be clearly focused, and has high universality and wide application prospect.
Description
Technical Field
The utility model relates to a biomechanics engineering research field, concretely relates to be applied to rotary system's real-time image device.
Background
With the rapid development of the aerospace industry, research on problems related to life health of astronauts is more and more concerned by various scholars. At present, aiming at long-time space flight, basic research which is deep to the level of cell and molecular biology is carried out by building a ground simulated microgravity effect experimental device. The common instruments for simulating the microgravity effect on the ground are a single-shaft rotation RCCS system and a double-shaft rotation Gravity Controller system researched and developed by NASA, and mainly culture the cells in a culture bottle by inoculating the cells in the culture bottle, placing the culture bottle in a single-shaft or double-shaft rotation environment, disturbing the perception of the cells to the direction of a Gravity vector and controlling the final Gravity vector sum to be zero, so as to realize two-dimensional or three-dimensional simulated microgravity effect culture on the cells in the bottle. Chinese patent application publication No. CN 101021517, "double-shaft drive frame type gyrator", published in 2007-08-22, also describes a device having a similar function to the GravityController system.
The device realizes in-vitro cell simulation microgravity effect culture by rotating the cells around the single shaft and the double shafts, but the growth condition of the cells cannot be observed and recorded in real time in the rotation process of the experiment. Most of the existing microscopic imaging systems are desktop microscopes or handheld microscopes, and are mostly used for imaging observation of cells which are static relative to a ground coordinate system, and no imaging device which can be carried in a revolving body and can carry out online observation in the revolving process relative to the ground is found, so that the growth state of the cells can not be monitored in real time in the revolving experiment process, inconvenience is caused in the experiment process for researchers, the pollution condition in a culture bottle can not be found in time, the experiment inspection reason can not be stopped in time, and unnecessary time waste is avoided.
SUMMERY OF THE UTILITY MODEL
The utility model discloses can be to the unable on-line observation of cell culture ware in the rotary system culturing cell in-process to present lack, lack the problem of effectual real-time imaging record, provide a gyration real-time imaging device that can adjust position in three dimension.
The utility model relates to a real-time imaging device applied to a rotary system, which comprises a rectangular rotary frame, a camera base, a first chute bracket and a second chute bracket,
the rectangular rotating frame is a hollow structure with two opposite side surfaces positioned in the X direction and two opposite beam structures positioned in the Y direction, a rotating shaft mounting hole of a rotating system is arranged at the central position of each side surface, each beam structure comprises an upper beam and a lower beam, a through hole is arranged on the upper beam, a cell culture device mounting hole is arranged on the lower beam,
the camera base is of a three-plate semi-surrounding structure with two wing ends, steps for positioning and mounting the camera are respectively arranged on the inner sides of three plates, and through holes are respectively arranged on the two wing ends;
the first sliding groove support is of a three-plate semi-surrounding structure, wherein a long sliding groove a extending along the Y direction is formed in the middle plate, long double sliding grooves b extending along the Z direction are formed in the two side plates respectively, and the long sliding grooves a are matched with through holes in two wing ends of the camera base, so that the position of the camera can be adjusted along the Y direction, and the camera base is fixedly connected with the first sliding groove support;
the second chute support comprises a pair of L-shaped plates, one end of each L-shaped plate is provided with a long double chute c extending along the X direction, the other end of each L-shaped plate is provided with a long chute d extending along the X direction, the long double chute c is matched with the long double chute b so that the position of the camera can be adjusted along the X direction and the Z direction and each L-shaped plate is fixedly connected with the first chute support, the long chute d is matched with the through hole of the upper beam so that the position of the camera can be adjusted along the X direction and each L-shaped plate is fixedly connected with the rectangular rotating frame, and a boss extending along the Z direction is arranged at the crossed position of the two ends of each L-shaped plate,
the X direction, the Y direction and the Z direction are mutually perpendicular, and the camera, the camera base and the first sliding groove support are accommodated in a hollow structure of the rectangular rotating frame.
The mutually parallel long double-sliding-groove b and the mutually parallel long double-sliding-groove c are matched with each other, the camera can be restrained from rotating relative to a Y coordinate axis, each L-shaped plate and the rectangular rotating frame are fixedly connected, the camera can be restrained from rotating relative to an X coordinate axis, and bosses extending along the Z direction are arranged at the cross positions of the two ends of each L-shaped plate, so that the camera can be restrained from rotating relative to a Z coordinate axis. In addition, the adjustment distance range of the camera along the X direction can be expanded by matching the two parallel long sliding chutes b with the two parallel long sliding chutes c.
In some embodiments, the positional adjustment and fixation of the camera may be achieved by bolts and nuts.
In some embodiments, the camera may have a resolution of 4K. The camera can carry out high-definition shooting and can transmit pictures to a computer used for a test in a wireless or wired mode in real time.
In some embodiments, the camera chassis may be manufactured using 3D printing techniques.
In some embodiments, the three plates of the camera stand may each be a hollowed-out structure.
In some embodiments, two cell culture device mounting holes may be provided on each lower beam.
The utility model has the advantages that: the imaging device can adjust the relative positions of the camera and the cell culture device in three dimensions, is suitable for cell culture devices of different types and different sizes, has high universality and wide application prospect; the utility model discloses can be used to help the researcher research to explore when the cell is cultivateed in the microgravity effect of gyration system simulation, real-time transmission and record cell image, the experimenter of being convenient for control cell growth state and acquire more experimental information.
Drawings
Fig. 1 is an assembly schematic diagram of the real-time imaging device of the present invention.
Fig. 2 is a schematic view of the rectangular rotating frame 1 of the real-time imaging device of the present invention.
Fig. 3 is a schematic view of the camera mount 3 of the real-time imaging device of the present invention.
Fig. 4 is a schematic diagram of the first chute holder 4 of the real-time imaging device of the present invention.
Fig. 5 is a schematic diagram of the second chute holder 5 of the real-time imaging device of the present invention.
Fig. 6 is an assembly diagram of another angle of the real-time imaging device according to the present invention.
Fig. 7 is a schematic top view of the assembly of the real-time imaging device of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings, and it is obvious that the described embodiments are only illustrative and are not intended to limit the present invention.
As shown in fig. 1, 6 and 7, the real-time imaging device applied to the revolving system of the present invention includes a rectangular rotating frame 1, a camera 2, a camera mount 3, a first chute support 4 and a second chute support 5.
As shown in fig. 2, the rectangular rotating frame 1 is a hollow structure having two opposing side surfaces 11 in the X direction and two opposing beam structures in the Y direction. The central point of each side 11 puts and is provided with rotation system rotation axis mounting hole 111, the utility model discloses an image device passes through rotation system rotation axis mounting hole 111 the totality and fixes on rotation system's rotation axis, along with rotation system's rotation axis. Each beam structure comprises an upper beam 12 and a lower beam 13, the upper beam 12 is provided with a through hole 121, the lower beam 13 is provided with a cell culture device mounting hole 131, and a cell culture device 6 for culturing cells is fixedly mounted at the bottom of the lower beam 13 of the rectangular rotating frame 1 through the cell culture device mounting hole 131. In this example, two cell culture device mounting holes 131 are provided on the two opposing lower beams 13, and two identical or different cell culture devices (e.g., parallel plate flow chambers, as shown in FIG. 7, or cell culture dishes) can be mounted in parallel to provide parallel experiments or control experiments.
As shown in fig. 3, the camera mount 3 is a three-plate semi-surrounding structure having two wing ends, wherein the three plates are respectively provided with steps for positioning and mounting the camera 2 on the inner sides thereof, and the two wing ends are respectively provided with through holes 31. In the present embodiment, the three plates of the camera mount 3 are respectively hollow structures, which creates a convenient operation space for a series of buttons and wire harness interfaces on the side of the camera 2. In particular, the camera stand 3 may be prepared using 3D printing techniques.
As shown in fig. 4, the first sliding chute holder 4 is a three-plate half-enclosed structure, wherein a long sliding chute a41 extending along the Y direction is provided on the middle plate, long double sliding chutes b42 extending in parallel along the Z direction are provided on the two side plates, respectively, and the long sliding chutes a41 are engaged with the through holes 31 on the two wing ends of the camera mount 3, so that the position of the camera 2 can be adjusted along the Y direction and the camera mount 3 is fixedly connected with the first sliding chute holder 4. In particular, the relative positions of the first chute bracket 4 and the camera mount 3 are adjusted and fixed by bolts and nuts.
As shown in fig. 5, the second chute holder 5 includes a pair of L-shaped plates 51, two ends of each L-shaped plate 51 are provided with an elongated double chute c511 and an elongated chute d512 extending in the X direction and parallel to each other, and the elongated double chute c511 and the elongated double chute b42 cooperate to enable the position of the camera 2 to be adjusted in the X direction and the Z direction and to fixedly connect each L-shaped plate 51 to the first chute holder 4 so as to restrain the camera 2 from rotating about the Y coordinate axis. The elongated sliding groove d512 is matched with the through hole 121 of the upper beam 12, so that the position of the camera 2 can be adjusted along the X direction and each L-shaped plate is fixedly connected with the rectangular rotating frame to restrain the camera 2 from rotating around the X coordinate axis. Specifically, bosses 513 extending in the Z direction are provided at the intersections of both ends of each L-shaped plate to restrain the camera 2 from rotating about the Z coordinate axis. In particular, the relative positions of the first and second chute brackets 4 and 5, and the relative positions of the second chute bracket 5 and the rectangular rotating frame 1 are adjusted and fixed by bolts and nuts.
The utility model discloses in, regard the central axis direction of rotation system rotation axis mounting hole 111 as the X direction, Y direction and Z direction mutually perpendicular, camera 2, camera seat 3 and first spout support 4 hold in the hollow structure of rectangle revolving frame 1.
Before imaging, the cell culture device 6 is installed on the rectangular rotating frame 1 through the cell culture device installing hole 131, the relative positions of the camera 2 and the cell culture device 6 are adjusted along the Y \ Z \ X three directions by utilizing the long chutes on the first chute support 4 and the second chute support 5, and the position of the camera 2 is fixed by utilizing bolts and nuts after cell imaging is clear. Then, the whole imaging device is installed on the rotating shaft of the rotary system through the rotating shaft installation hole 111 of the rotary system, and when the whole imaging device rotates along with the rotating shaft, the imaging of the camera 2 can be synchronized to the terminal in a wireless mode, so that the microscopic imaging of the rotating cell culture device is realized.
Particularly, the relative positions of the camera 2 and the cell culture device 6 are adjusted along the Y \ Z \ X directions by utilizing the long chutes on the first chute support 4 and the second chute support 5, so that the camera 2 can be adapted to the cell culture devices 6 with different types and sizes.
Particularly, the definition of the camera 2 is 4K, the camera can carry out video and photo imaging of various systems, and can clearly take pictures or record videos of the growth condition of cells in the cell culture device in real time and transmit the pictures or records to a computer of an experimenter in real time for observation and recording.
The utility model discloses can be used to help the researcher research to explore when the cell is cultivateed in the microgravity effect of gyration system simulation, real-time transmission and record cell image, the experimenter of being convenient for control cell growth state and acquire more experimental information. The imaging device is adaptive to cell cultivators of different types and sizes, can accurately adjust the camera to the imaging view field range by adjusting the sliding groove support, and enables the lens to be clearly focused, and has high universality and wide application prospect.
It will be apparent to those skilled in the art that various modifications and improvements can be made to the embodiments of the present invention without departing from the inventive concept of the present application, which falls within the scope of the present application.
Claims (6)
1. A real-time imaging device applied to a rotary system is characterized by comprising a rectangular rotary frame, a camera base, a first chute bracket and a second chute bracket,
the rectangular rotating frame is a hollow structure with two opposite side surfaces positioned in the X direction and two opposite beam structures positioned in the Y direction, a rotating shaft mounting hole of a rotating system is arranged at the central position of each side surface, each beam structure comprises an upper beam and a lower beam, a through hole is arranged on the upper beam, a cell culture device mounting hole is arranged on the lower beam,
the camera base is of a three-plate semi-surrounding structure with two wing ends, steps for positioning and mounting the camera are respectively arranged on the inner sides of three plates, and through holes are respectively arranged on the two wing ends;
the first sliding groove support is of a three-plate semi-surrounding structure, wherein a long sliding groove a extending along the Y direction is formed in the middle plate, long double sliding grooves b extending in parallel along the Z direction are formed in the two side plates respectively, and the long sliding grooves a are matched with through holes in two wing ends of the camera base, so that the position of the camera can be adjusted along the Y direction, and the camera base is fixedly connected with the first sliding groove support;
the second chute support comprises a pair of L-shaped plates, one end of each L-shaped plate is provided with a long double chute c extending in parallel along the X direction, the other end of each L-shaped plate is provided with a long chute d extending along the X direction, the long double chute c is matched with the long double chute b so that the position of the camera can be adjusted along the X direction and the Z direction and each L-shaped plate is fixedly connected with the first chute support, the long chute d is matched with the through hole of the upper beam so that the position of the camera can be adjusted along the X direction and each L-shaped plate is fixedly connected with the rectangular rotating frame, and a boss extending along the Z direction is arranged at the crossed position of the two ends of each L-shaped plate,
the X direction, the Y direction and the Z direction are mutually perpendicular, and the camera, the camera base and the first sliding groove support are accommodated in a hollow structure of the rectangular rotating frame.
2. The apparatus of claim 1, wherein the adjustment and fixation of the position of the camera is achieved by a bolt and a nut.
3. The apparatus of claim 1, wherein the camera has a resolution of 4K.
4. The apparatus of claim 1, wherein the camera rig is manufactured using 3D printing techniques.
5. The apparatus of claim 1, wherein each of the three plates of the camera stand is a hollowed-out structure.
6. The apparatus of claim 1, wherein each lower beam has two cell culture device mounting holes disposed therein.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920851683.XU CN210481391U (en) | 2019-06-06 | 2019-06-06 | Real-time imaging device applied to rotation system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920851683.XU CN210481391U (en) | 2019-06-06 | 2019-06-06 | Real-time imaging device applied to rotation system |
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| Publication Number | Publication Date |
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| CN210481391U true CN210481391U (en) | 2020-05-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201920851683.XU Expired - Fee Related CN210481391U (en) | 2019-06-06 | 2019-06-06 | Real-time imaging device applied to rotation system |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112511738A (en) * | 2020-11-19 | 2021-03-16 | 北京麦科伦科技有限公司 | Control method, control device, electronic equipment and readable storage medium |
| CN113388500A (en) * | 2021-06-01 | 2021-09-14 | 南京大学 | Cell culture monitoring system and method capable of being used under microgravity |
-
2019
- 2019-06-06 CN CN201920851683.XU patent/CN210481391U/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112511738A (en) * | 2020-11-19 | 2021-03-16 | 北京麦科伦科技有限公司 | Control method, control device, electronic equipment and readable storage medium |
| CN113388500A (en) * | 2021-06-01 | 2021-09-14 | 南京大学 | Cell culture monitoring system and method capable of being used under microgravity |
| CN113388500B (en) * | 2021-06-01 | 2024-03-12 | 南京大学 | Cell culture monitoring system and method applicable to microgravity |
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Granted publication date: 20200508 Termination date: 20210606 |