CN210472261U

CN210472261U - Ablation plugging device

Info

Publication number: CN210472261U
Application number: CN201821708272.7U
Authority: CN
Inventors: 王永胜; 李建民; 丘家明
Original assignee: Hangzhou Nori Medical Technology Co Ltd
Current assignee: Hangzhou Dinova EP Technology Co Ltd
Priority date: 2018-10-19
Filing date: 2018-10-19
Publication date: 2020-05-08
Anticipated expiration: 2028-10-19

Abstract

The utility model provides an melt plugging device, it is including the shutoff piece that is used for sealing left auricle and melts the piece, it includes first electrode and second electrode to melt the piece, first electrode set up in on the outer wall of shutoff piece, first electrode passes through wire electric connection in radio frequency power supply, the second electrode passes through wire ground connection, first electrode with the second electrode forms the electric current return circuit in order to receive radio frequency power supply's energy melts the inner wall of left auricle.

Description

Ablation plugging device

Technical Field

The utility model relates to an intervene medical instrument technical field, especially relate to an melt plugging device, should melt plugging device and utilize percutaneous puncture's mode to carry its position of carrying heart left auricle through conveying pipe, can realize melting and the shutoff to left auricle simultaneously.

Background

Atrial fibrillation (short for atrial fibrillation) is the most common persistent arrhythmia, and the incidence rate of atrial fibrillation is increased continuously with the increase of age, and the population over 75 years old can reach 10 percent. The incidence of atrial fibrillation is also closely related to coronary heart disease, hypertension, heart failure and other diseases. Because of its special shape and structure, the Left Atrial Appendage (LAA) is not only the most important site for the formation of atrial fibrillation thrombus, but also one of the key regions for its generation and maintenance, and some patients with atrial fibrillation can benefit from active left atrial appendage electrical isolation (LAAI).

Transcatheter radio frequency ablation is one of the treatment hot spots of atrial fibrillation today. Radiofrequency ablation therapy includes two major aspects: for atrial fibrillation which is difficult to control by medicines, an atrioventricular node is ablated and improved or completely ablated to control the ventricular rate; intra-atrial linear ablation or ablation of the pulmonary veins (including point and ring ablations) prevents atrial fibrillation recurrence.

Although the radiofrequency ablation operation is still the current main operation for atrial fibrillation, the sinus rhythm is recovered through the operation, the main purposes are to improve the symptoms of patients with palpitation, chest distress and the like and improve the heart function, part of the patients need lifelong anticoagulation treatment to solve the problem of thromboembolism even if the radiofrequency ablation operation is successful, and the patients need to continuously take anticoagulation medicines after the radiofrequency ablation operation, so the economic burden of the patients is increased, and the life quality of the patients is reduced.

On the other hand, the percutaneous left atrial appendage occlusion device can achieve the purpose of preventing atrial fibrillation thromboembolism by occluding LAA through a special occluder, is a treatment method which is developed in recent years, has small wound, is simple to operate and consumes less time, and currently, many scholars are dedicated to research on the technology for preventing atrial fibrillation thromboembolism and make great progress. The basic structure of the existing ablation occlusion device is similar, an expandable high polymer membrane is coated outside a self-expansion nickel-titanium memory alloy cage-shaped structure support, and the occlusion device is placed into the left auricle for occlusion. The high molecular polymer film can seal the entrance of the left auricle atrium, isolate the left auricle atrium and the left atrial body part, and prevent the blood flow from communicating. After the plugging device is placed, the endothelial cells in the left atrium can creep and grow on the surface of the high-molecular polymer membrane, and new endothelium is formed after a period of time. However, the left atrial appendage occlusion alone can only prevent stroke, but cannot improve atrial fibrillation symptoms.

From the overall height of atrial fibrillation treatment, sinus rhythm restoration and stroke prevention are two concurrent treatment strategies, which are not primary and secondary in importance. At present, some cardiovascular experts adopt a treatment method combining catheter radio frequency ablation and left atrial appendage occlusion, and have obtained a plurality of cases of successful treatment of atrial fibrillation. In the combined treatment method, through left atrial appendage occlusion surgery, compared with single oral anticoagulant or atrial fibrillation ablation, the patient can still obtain good stroke prevention effect under the condition of not needing to take the anticoagulant for the whole life; and the symptoms of patients with atrial fibrillation are improved by combining with the radio frequency ablation of the catheter to recover and maintain the sinus rhythm, so that the patients can obtain stable long-term treatment effect. The catheter radiofrequency ablation device used in the existing combined treatment method generally adopts a monopolar radiofrequency device, that is, the monopolar radiofrequency device comprises a working electrode arranged on the radiofrequency ablation device and a return electrode arranged at a position (such as the back of a patient) far away from the working electrode, and the working electrode and the return electrode form a current return circuit and receive energy to ablate the inner wall of the left atrial appendage.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide an easily gather energy, melt effectual melting plugging device.

In order to solve the technical problem, the utility model provides an melt plugging device, it is including the shutoff piece and the piece of melting that are used for sealing the left auricle, it includes first electrode and second electrode to melt the piece, first electrode set up in on the outer wall of shutoff piece, first electrode passes through wire electric connection in radio frequency power supply, the second electrode passes through wire ground connection, first electrode with the second electrode forms the electric current return circuit in order to receive the inner wall of radio frequency power supply melts the inner wall of left auricle.

The utility model provides an it includes the shutoff piece and melts the piece to melt plugging device, the shutoff piece is used for sealing the entry of left auricle, melts the first electrode of piece set up in on the outer wall of shutoff piece, first electrode electric connection is in radio frequency power supply, the second electrode passes through wire direct ground connection, so that it is right to melt the piece the inner wall of left auricle melts, increases the cure success rate that the room quivers and melts. Because the ablation plugging device is respectively provided with the first electrode and the second electrode, and the second electrode is directly grounded through the conducting wire, the distance between the first electrode and the second electrode is short, the distribution of current is easy to control, so that the radio frequency energy can be concentrated on the inner wall of the left auricle and released between the first electrode and the second electrode, namely, the energy is easy to gather, the sustainable damage can be caused, the loss of the radio frequency energy on the electrodes is prevented, the ablation efficiency is improved, and the damage of other tissues of the body is prevented.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.

Fig. 1 is a schematic structural view of a first embodiment of an ablation occlusion device according to a first embodiment of the present invention;

FIG. 2 is a top view of FIG. 1;

fig. 3 is a diagram illustrating the state of the ablation occlusion device released in the left atrial appendage according to the first embodiment of the present invention;

FIG. 4 is a schematic structural view of a second embodiment of the ablation occlusion device of the first embodiment;

FIG. 5 is a schematic structural view of a third embodiment of the ablation occlusion device of the first embodiment;

FIG. 6 is a schematic structural view of a fourth embodiment of the ablation occlusion device of the first embodiment;

fig. 7 is a schematic structural view of a fifth embodiment of the ablation occlusion device of the first embodiment;

fig. 8 is a schematic perspective view of a first embodiment of an ablation occlusion device according to a second embodiment of the present invention;

FIG. 9 is a schematic front view of the structure of FIG. 8;

fig. 10 is a schematic structural view of a second embodiment of the ablation occlusion device according to a second embodiment of the present invention;

fig. 11 is a schematic structural view of an ablation occlusion device according to a third embodiment of the present invention;

fig. 12 is a schematic view of the ablation occlusion device according to the third embodiment of the present invention being released in the left atrial appendage;

fig. 13 is a schematic structural view of a first embodiment of an ablation occlusion device according to a fourth embodiment of the present invention;

fig. 14 is a schematic structural view of a second embodiment of an ablation occlusion device according to a fourth embodiment of the present invention;

fig. 15 is a schematic structural view of an ablation occlusion device according to a fifth embodiment of the present invention;

fig. 16 is a schematic structural view of a first embodiment of an ablation occlusion device according to a sixth embodiment of the present invention;

fig. 17 is a schematic structural view of a second embodiment of the ablation occlusion device of the sixth embodiment;

FIG. 18 is a schematic structural view of a third embodiment of an ablation occlusion device in accordance with a sixth embodiment;

fig. 19 is a schematic structural view of an ablation occlusion device according to a seventh embodiment of the present invention;

fig. 20 is a schematic structural view of a first embodiment of an ablation occlusion device according to an eighth embodiment of the present invention;

fig. 21 is a schematic structural view of a second embodiment of the ablation occlusion device of the eighth embodiment;

fig. 22 is a schematic structural view of an ablation occlusion device according to a ninth embodiment of the present invention.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without any creative effort belong to the protection scope of the present invention.

In the description of the present invention, the term "proximal" refers to the end near the left atrial location of the heart, and the term "distal" refers to the end away from the left atrial location of the heart. The location of entry into the left atrial appendage from the left atrium is called the entrance to the left atrial appendage, and the location near the entrance to the left atrial appendage is the neck of the left atrial appendage. The axial direction refers to the direction of the central axis of the device, and the radial direction is the direction perpendicular to the central axis, and this definition is only for the convenience of expression and can not be understood as the limitation of the present invention.

Referring to fig. 1-3 together, fig. 1 is a schematic structural view of a first embodiment of an ablation occlusion device according to a first embodiment of the present invention, fig. 2 is a top view of fig. 1, and fig. 3 is a state view of the ablation occlusion device according to the first embodiment of the present invention released in the left atrial appendage. The utility model provides an ablation occlusion device 100, it includes a shutoff piece 20 that is used for sealing the entry 306 of left atrial appendage 305, and set up in an ablation piece 50 on shutoff piece 20. The ablating member 50 includes a first electrode 52 and a second electrode, the first electrode 52 is disposed on the outer wall of the blocking member 20, and the first electrode 52 is insulated from the blocking member 20. The first electrode 52 is electrically connected to a radio frequency power source through a wire 53, the second electrode is directly grounded through a wire, and the first electrode 52 and the second electrode form a current loop to receive energy for ablating the inner wall of the left atrial appendage 305. When the ablation blocking device 100 is implanted in the left atrial appendage 305, the outer wall surface of the blocking piece 20 is attached to the inner wall of the left atrial appendage 305, the first electrode 52 is attached to the inner wall of the left atrial appendage 305, and the first electrode 305 receives the energy of the radio frequency power supply and is used for ablating the inner wall of the left atrial appendage.

In the present invention, the first electrode 52 is used as an electrode for ablation, and the second electrode is used as a grounding electrode.

The closure 20 includes a metal support frame 22 that fits against the inner wall of the left atrial appendage 305. In this embodiment, the second electrode of the ablating member 50 is the metal supporting framework 22, i.e. the metal supporting framework 22 is directly grounded as the second electrode of the ablating member 50 through a conducting wire 53.

The utility model discloses an melt plugging device 100 including shutoff piece 20 and set up in melt piece 50 on the shutoff piece 20, the outer wall surface of shutoff piece 20 laminate in the inner wall of left atrial appendage 305, shutoff piece 20 is used for sealing the entry 306 of left atrial appendage 305, melt 50 first electrode 52 around in the outer wall surface of shutoff piece 20 is last, first electrode 52 laminates in the inner wall of left atrial appendage 305. The first electrode 52 is electrically connected to a radio frequency power supply, and the second electrode is directly grounded through a lead, so that the ablation piece 50 ablates the inner wall of the left atrial appendage 305, and the cure success rate of atrial fibrillation ablation is increased. Because the first electrode 52 and the second electrode are respectively arranged on the occlusion piece 20 of the ablation occlusion device 100, and the second electrode is directly grounded through a wire, the distance between the first electrode 52 and the second electrode is short, the distribution of the current of the ablation piece 50 is easily controlled, the radio frequency energy can be released between the first electrode 52 and the second electrode by concentrating on the inner wall of the left atrial appendage 305, i.e., the energy is easily gathered and can cause continuous injury, the loss of the radio frequency energy on the electrodes is prevented, the ablation efficiency is improved, and the injury of other tissues of the body is prevented.

As shown in fig. 3, the occluding member 20 is used to occlude and separate the left atrium 302 from the left atrial appendage 305 to prevent thrombus within the left atrial appendage 305 from entering the left atrium 302. The first electrode 52 is connected to a radio frequency power source through a wire 53, and the second electrode is directly grounded through the wire 53, that is, the metal supporting framework 22 is directly grounded through the wire 53. In each of the figures, the occluding member 20 and the ablating member 50 of the ablation occluding device 100 are in a free state, that is, a state in which the ablation occluding device 100 is implanted in the ostium 306 of the left atrial appendage 305. For ease of delivery, both the occluding member 20 and the ablating member 50 may be radially compressed to reduce the diameter thereof into the sheath, and the various components of the ablation occluding device 100 may also be radially compressible in a lattice, rod-like structure, frame structure, or soft collapsible structure.

The first electrode 52 is disposed on the outer wall surface of the metal supporting frame 22, and the first electrode 52 is insulated from the metal supporting frame 22, i.e., the second electrode. Because the first electrode 52 is disposed on the outer wall surface of the metal supporting framework 22, and the ablation piece 50 uses the metal supporting framework 22 as a grounding electrode, the distance between the first electrode 52 and the second electrode is short, and energy can be gathered between the first electrode 52 and the metal supporting framework 22, so that the ablation effect of the ablation piece 50 can be improved, and the damage of current to other parts of the heart and other tissues can be reduced.

The metal supporting framework 22 may be woven by metal wires, and the metal supporting framework 22 may be a radially compressed grid structure, a rod structure, a frame structure or a soft foldable structure, or may be formed by cutting metal tubes to form a grid or frame structure. The metal wire can be nickel-titanium alloy, cobalt-chromium alloy, stainless steel or other metal materials with good biocompatibility, preferably a superelastic shape memory alloy nickel-titanium wire, and the manufacturing process of the metal wire is the same as that of the framework of the traditional left atrial appendage occluder, and is not repeated herein.

The metal supporting framework 22 is a cylindrical structure, and specifically, the metal supporting framework 22 may be a cylindrical structure, a truncated cone structure, a conical structure or a combination thereof, and the structures all have an outer wall surface attached to the inner wall of the left atrial appendage 305; in addition to the regular structure described above, the metal supporting framework 22 may also be a random structure having a partial ring attached to the inner wall surface of the left atrial appendage 305, this partial ring also having an outer wall surface that conforms to the inner wall of the left atrial appendage 305. In this embodiment, the metal supporting frame 22 has a grid-like cylindrical structure.

The closure 20 comprises a sealing portion 221, a connecting portion 223 and an anchoring portion 225, the sealing portion 221 being located at the proximal end of the closure 20 for closing the entrance 306 of the left atrial appendage 305; the anchoring portion 225 is located at the distal end of the occluding member 20 for anchoring the ablation occluding device 100 in the left atrial appendage 305; the connecting portion 223 is located between the sealing portion 221 and the anchoring portion 223 for connecting the sealing portion 221 and the anchoring portion 225, the first electrode 52 can be selectively disposed on the sealing portion 221 or the connecting portion 223 or the anchoring portion 225 according to the specific location to be ablated. In this embodiment, the first electrode 52 of the ablating member 50 is disposed on the connecting portion 223. Specifically, the first electrode 52 surrounds the outer wall surface of the connecting portion 223, so that the first electrode 52 can be attached to the inner wall of the left atrial appendage 305 to be ablated.

The sealing portion 221 includes a mesh frame 2212 for supporting the proximal portion of the framework 22, at least one layer of flow blocking film 2214 disposed inside the mesh frame 2212, and a connecting end 2215 located at the proximal end of the mesh frame 2212. The shape of the sealing portion 221 may be a disk shape, a cylindrical shape, or a stepped shape formed by combining a disk shape and a cylindrical shape. In this embodiment, the sealing portion 221 is cylindrical, and the grid frame 2212 is formed by weaving a superelastic shape memory alloy nickel-titanium wire. In this embodiment, the diameter of the mesh frame 2212 is the same as the inner diameter of the left atrial appendage 305, the mesh frame 2212 can be inserted into the neck of the left atrial appendage 305, and the outer wall surface of the mesh frame 2212 is attached to the inner wall of the neck of the left atrial appendage 305.

The sealing portion 221 achieves closure of the entrance 306 of the left atrial appendage 305 by a flow blocking membrane 2214 disposed therein. The flow blocking film 2214 may be fixed inside the grid frame 2212 by sewing or bonding, and the flow blocking film 2214 may be selected from PET or PTFE coating.

The connecting end 2215 is located at the center of the end face of the proximal end of the metal supporting frame 22, that is, the connecting end 2215 is tied to the head end of the wire at the proximal end face of the metal supporting frame 22. Preferably, the connecting end 2215 is a bolt head, and the connecting end 2215 is used for detachable connection with the conveyor. In this embodiment, the wire 53 is connected to the metal supporting frame 22 through the connecting end 2215, that is, the wire 53 connected to the metal supporting frame 22 is directly connected to the wire on the conveyor and grounded.

The connecting portion 223 includes a mesh frame 2232 between the sealing portion 221 and the anchoring portion 225 of the metal supporting frame 22, and at least one layer of a flow blocking film 2234 disposed inside the mesh frame 2232. The shape of the mesh frame 2232 is cylindrical, the outer wall surface of the mesh frame 2232 is attached to the inner wall of the left atrial appendage 305 for a circle, and the mesh frame 2232 is woven by metal wires to form a cross mesh. The first electrode 52 is fixedly connected to the outer wall of the grid frame 2232, and specifically, the first electrode 52 is disposed at least one turn along the annular outer wall surface of the grid frame 2232. The first electrode 52 can be fixed on the outer wall of the grid frame 2232 by sewing or winding, and the first electrode 52 fixed on the grid frame 2232 is directly connected to the rf source, i.e. the first electrode 52 is connected to the rf source via the lead 53 and the lead on the conveyor.

In this embodiment, the first electrode 52 is a gapless ring electrode, and the lead 53 and the first electrode 52 are fixedly connected by welding or steel sleeve. The first electrode 52 and the connecting portion 223 are insulated, that is, at least a portion of the mesh frame 2232 that contacts the first electrode 52 is insulated, that is, a short circuit between the first electrode 52 and the second electrode is prevented. In this case, the second electrode is a larger metal mesh structure, which is equivalent to a dispersive electrode, so that the rf energy can be focused on the first electrode 52 for ablation, thereby achieving better ablation effect. The insulating treatment is performed by coating an insulating coating on the outer wall surface of the metal supporting skeleton 22 contacting the first electrode 52, or inserting an insulating sleeve on the metal wire contacting the metal supporting skeleton 22 and the first electrode 52, wherein the insulating sleeve is wrapped on the outer surface of the metal wire of the metal supporting skeleton 22, and the coating or the sleeve is made of FEP/ETFE/PFA. In this embodiment, the first electrode 52 is selected to be a single-turn electrode.

The first electrode 52 is between 1-12mm, preferably 5mm in this embodiment, in axial length.

The anchor portion 225 includes an anchor body 2252 that is a distal portion of the metal support skeleton 22, at least one layer of resistive film 2254 disposed within the anchor body 2252, a plurality of anchors 2255, and a seal 2257 at a distal end of the anchor body 2252. The anchor body 2252 is a cylindrical structure, preferably a cylindrical structure, i.e. the diameter of the anchor body 2252 is substantially the same as the inner diameter of the left atrial appendage 305, the contact between the outer wall surface of the anchor body 2252 and the inner wall of the left atrial appendage 305 creates friction, and the anchor body 2252 can be used directly to anchor the ablation occlusion device 100.

Further, a plurality of anchoring thorns 2255 are arranged on the anchoring body 2252 for anchoring on the inner wall of the left atrial appendage 50, the anchoring thorns 2255 are uniformly arranged around the outer wall of the anchoring body 2252, and after the ablation occlusion device 100 is implanted, the anchoring thorns 2255 penetrate into the inner wall of the left atrial appendage 305 to further anchor the ablation occlusion device 100, so that the anchoring stability is better with the anchoring thorns 2255, and the ablation occlusion device 100 is prevented from falling off. The distal end of the cylindrical anchor body 2252 is closed and the proximal end is integrally connected to the connecting portion 223.

The flow blocking membrane 2254 is radially disposed inside the anchor body 2252, the periphery of the flow blocking membrane 2254 is fixed inside the anchor body 2252 by sewing or bonding, and the flow blocking membrane 2254 is made of PET or PTFE film. In this embodiment, two spaced apart blocker membranes 2254 are radially disposed within the anchor body 2252.

The anchor stabs 2255 and the anchor main body 2252 are integrated or fixedly connected, in this embodiment, the steel sleeves 2257 are used to connect the anchor stabs 2255 and the anchor main body 2252 together, the positions are located at the distal end of the metal supporting framework 22, the number of the anchor stabs is 6-20, the opening angle of the anchor stabs 2255 is 30-60 degrees, the direction is toward the proximal end, and the length of the anchor stabs 2255 is 0.5-4 mm. The seal 2257 is located in the center of the distal end surface of the anchoring portion 225, i.e. the seal 2257 is tied to the end of the wire of the distal end surface of the metal support framework 22. The barb structure is disposed on the anchoring portion 225 and is mainly used to strengthen and stabilize the entire ablation occlusion device 100.

The sealing part 221, the connecting part 223, and the anchor part 225 in this embodiment are integrally formed, that is, the mesh frame 2212 of the sealing part 221, the mesh frame 2232 of the connecting part 223, and the anchor body 2252 of the anchor part 225 may be integrally formed with the metal supporting frame 22, or may be integrally connected to the metal supporting frame 22 by welding or the like.

As shown in fig. 3, the ablation occlusion device 100 of the first embodiment of the present invention is released in the left atrial appendage 305. During operation, the connection end 2215 on the sealing portion 221 can be connected with the delivery catheter 70 through a bolt mode, and is collected in the delivery sheath 80 with a smaller diameter, and then enters the inferior vena cava 301 through femoral vein puncture, enters the right atrium 303, and enters the left atrium 302 through interatrial puncture. When the ablation occlusion device 100 is released, the position of the ablation occlusion device 100 in the left atrial appendage 305 is positioned by means of radiography and ultrasound to ensure that the anchoring part 225 is released inside the left atrial appendage 305 after release and the anchoring thorn 2255 hooks into the inner wall of the left atrial appendage 305; the outer wall surface of the connecting portion 223 is closely attached to the inner wall of the left atrial appendage 305 near the entrance 306, and the flow blocking film 2214 in the sealing portion 221 blocks the entrance 306 of the left atrial appendage 305, so as to prevent blood from entering the left atrial appendage 305 and thrombus in the left atrial appendage 305 from flowing into the left atrium 302. After the ablation occlusion device 100 is released in the left atrial appendage 305, the lead 53 connected to the first electrode 52 is connected to a radio frequency source, i.e., the first electrode 52 is connected to a radio frequency ablation generator; the conducting wire 53 connected to the second electrode is directly grounded through the delivery catheter 70, that is, the metal supporting framework 22 is directly grounded through the conducting wire 53, and the first electrode 52 and the second electrode form a current loop. Adjusting the radio frequency ablation parameters, transmitting radio frequency ablation energy to the first electrode 52 of the ablation occlusion device 100 through the lead 53, and receiving the radio frequency ablation energy by the first electrode 52, thereby realizing an ablation operation, namely performing the ablation operation on the inner wall of the left atrial appendage 305 attached to the first electrode 52. After ablation is complete, the lead 53 may be detached from the first electrode 52 and the metal supporting framework 22. The outer surface of the conducting wire 53 is insulated from the outer surface of the delivery catheter 70, i.e. the surface of the delivery catheter 70 and/or the conducting wire 53 is insulated in a manner of insulating coating or insulating sleeve coated with a polymer insulating material, preferably PTFE, FEP, ETFE, PFA or PEEK (polyetheretherketone) sleeve, and thus the first electrode 52 in this embodiment is an uninterrupted ring electrode, so that ablation blocking of all target points in the circumferential direction of the inner wall of the left atrial appendage 305 can be achieved. After the ablation procedure is completed, the delivery catheter 70 is detached from the ablation occlusion device 100, and the ablation occlusion device 100 remains in the left atrial appendage 305 to achieve long-term occlusion performance. The utility model provides an it melts plugging device 100 can utilize in an operation to melt plugging device 100 self structure and successively realize that the shutoff of the entry 306 of left atrial appendage 305 is blocked with the complete ablation of the inner wall of efficient realization to left atrial appendage 305 to resume sinus rhythm.

In other embodiments, the first electrode 52 may be disposed on an outer wall of the sealing portion 221 or an outer wall of the anchoring portion 225, specifically, the first electrode 52 may be circumferentially disposed on an outer wall of the mesh frame 2212 of the sealing portion 221, and the first electrode 52 may also be circumferentially disposed on an outer wall of the anchoring body 2252 of the anchoring portion 225. The first electrode 52 provided in the circumferential direction of the sealing portion 221 is insulated from the sealing portion 221, and the first electrode 52 provided in the circumferential direction of the anchor portion 225 is insulated from the anchor portion 225.

In other embodiments, two or more rings of annular electrodes may be circumferentially disposed on the outer wall surface of the metal support armature 22, and these rings of electrodes constitute the first electrode 52, and the rings of electrodes may be continuous, or intermittent, or a combination of both; the multiple ring electrodes may be arranged in parallel or staggered in the axial direction of the metal supporting framework 22.

Referring to fig. 4, fig. 4 is a schematic structural view of a second embodiment of the ablation occlusion device of the first embodiment. The second embodiment of the ablation occlusion device is similar in structure to the first embodiment except that: the structure of the first electrode in the second embodiment is different from that in the first embodiment, in the second embodiment, the first electrode 52a includes a plurality of spaced dot-shaped electrodes 522, the dot-shaped electrodes 522 are disposed at least one turn along the circumferential direction of the outer wall surface of the metal supporting skeleton 22, and specifically, the dot-shaped electrodes 522 are disposed at least one turn along the outer wall surface of the mesh frame 2232 of the connecting portion 223. Each dot-shaped electrode 522 and the metal supporting framework 22 are insulated by coating an insulating coating on the outer wall surface of the metal supporting framework 22 contacting with the dot-shaped electrode 522, or inserting an insulating sleeve on the metal wire contacting with the dot-shaped electrode 522 of the metal supporting framework 22, wherein the insulating sleeve wraps the outer surface of the metal wire of the metal supporting framework 22, and the coating or sleeve is made of FEP/ETFE/PFA. The point-like electrodes 522 are used as ablation electrodes, the point-like electrodes 522 are connected in series through a lead wire and then connected to the lead wire 53, and the lead wire 53 is connected to a radio frequency power supply; the metal supporting framework 22 is used as a second electrode, namely a grounding electrode, of the ablation occlusion device 100, and the metal supporting framework 22 is directly grounded through the lead 53.

In other embodiments, the at least one circle of dot-shaped electrodes 522 may be disposed on the outer wall surface of the mesh frame 2212 of the sealing part 221, or may be disposed on the outer wall surface of the anchor main body 2252 of the anchor part 225.

Referring to fig. 5, fig. 5 is a schematic structural view of a third embodiment of the ablation occlusion device of the first embodiment. The third embodiment of the ablation occlusion device is similar in structure to the first embodiment except that: the first electrode in the third embodiment has a structure different from that in the first embodiment, in the third embodiment, the first electrode 52b includes a plurality of spaced rod-shaped electrodes 523, each rod-shaped electrode 523 extends in the axial direction of the metal supporting skeleton 22, and the rod-shaped electrodes 523 are arranged at least one turn in the circumferential direction of the outer wall surface of the metal supporting skeleton 22. Specifically, the rod electrodes 523 are arranged at least once along the outer wall surface of the mesh frame 2232 of the connection portion 223. Each rod electrode 523 and the metal supporting skeleton 22 are insulated, that is, each rod electrode 523 and the outer wall surface of the grid frame 2232 are insulated, in a manner that an insulating coating is coated on the outer wall surface of the metal supporting skeleton 22 contacting with the rod electrode 523, or an insulating sleeve is inserted on the metal wire contacting with the rod electrode 523 of the metal supporting skeleton 22, and the insulating sleeve is wrapped on the outer surface of the metal wire of the metal supporting skeleton 22, and the coating or the sleeve is made of FEP/ETFE/PFA. The rod-shaped electrodes 523 are used as ablation electrodes, the rod-shaped electrodes 523 are connected in series through a conducting wire and then connected to the conducting wire 53, and the conducting wire 53 is connected to a radio frequency power supply; the metal supporting framework 22 is used as a second electrode, namely a grounding electrode, of the ablation occlusion device 100, and the metal supporting framework 22 is directly grounded through the lead 53.

In other embodiments, the at least one loop of rod-shaped electrodes 523 may be disposed on the outer wall surface of the mesh frame 2212 of the sealing portion 221, or may be disposed on the outer wall surface of the anchor main body 2252 of the anchor portion 225.

Referring to fig. 6, fig. 6 is a schematic structural view of a fourth implementation of the ablation occlusion device of the first embodiment. The fourth embodiment of the ablation occlusion device is similar in structure to the first embodiment except that: the structure of the first electrode in the fourth embodiment is different from that in the first embodiment, in the fourth embodiment, the first electrode 52c is a single-turn intermittent annular electrode provided in the circumferential direction of the outer wall of the metal supporting skeleton 22, the annular electrode and the metal supporting skeleton 22 are insulated from each other, and the insulating treatment between the annular electrode and the metal supporting skeleton 22 is performed in the same manner as the insulating treatment between the first electrode 52 and the connecting portion 223 in the first embodiment. The annular electrode is connected in series through a lead and then connected to a lead 53, and the lead 53 is connected with a radio frequency power supply; the metal supporting framework 22 is used as a second electrode, namely a grounding electrode, of the ablation occlusion device 100, and the metal supporting framework 22 is directly grounded through the lead 53.

In this embodiment, the single-turn discontinuous ring-shaped electrode is provided on the outer wall surface of the mesh frame 2232 of the connection portion 223.

In other embodiments, the single-turn discontinuous ring-shaped electrode may be disposed on the outer wall surface of the mesh frame 2212 of the sealing portion 221, or may be disposed on the outer wall surface of the anchor body 2252 of the anchor portion 225.

In other embodiments, two or more intermittent ring-shaped electrodes are provided as electrodes for ablation on the outer wall surface of the mesh frame 2232 of the connecting portion 223, on the outer wall surface of the mesh frame 2212 of the sealing portion 221, or on the outer wall surface of the anchor body 2252 of the anchor portion 225.

Referring to fig. 7, fig. 7 is a schematic structural view of a fifth implementation manner of the ablation occlusion device of the first embodiment. The fifth embodiment of the ablation occlusion device is similar in structure to the first embodiment except that: in a fifth embodiment, the metal supporting skeleton 22 is provided with an insulating coating 54 isolating the first electrode 52 from the metal supporting skeleton 22, at least at the outer wall surface in contact with the first electrode 52. Specifically, an annular insulating coating 54 is coated between the outer wall surface of the grid frame 2212 of the connecting portion 223 and the contact surface of the first electrode 52. In other embodiments, the outer wall surfaces of the sealing portion 221, the connecting portion 223 and the anchoring portion 225 are all wrapped with insulating coatings, and the first electrode 52 may be circumferentially disposed on the outer wall surface of the sealing portion 221, the outer wall surface of the connecting portion 223 and the outer wall surface of the connecting portion 223.

Referring to fig. 8 and 9, fig. 8 is a schematic perspective view of a first embodiment of an ablation occlusion device according to a second embodiment of the present invention; fig. 9 is a schematic front view of the structure of fig. 8. The structure of the first embodiment of the ablation occlusion device provided by the second embodiment of the present invention is similar to that of the first embodiment, except that: in the first embodiment of the second embodiment, the end surface of the anchoring portion 225 of the ablation occlusion device 100, which is away from the sealing portion 221, is provided with an opening structure, specifically, the distal end of the anchoring body 2252 is open, and the distal end of the anchoring portion 225 is not sealed.

The structure of the first electrode 52 in this embodiment is the same as that in the first embodiment, i.e., a dot-shaped electrode, a rod-shaped electrode, a single-turn uninterrupted arrangement or a single-turn interrupted arrangement may be provided, or a combination of the above electrodes. The second pole in this embodiment is also a metal support armature 22.

Referring to fig. 10, fig. 10 is a schematic structural view of a second embodiment of an ablation occlusion device according to a second embodiment of the present invention. The second embodiment of the ablation occlusion device structure provided by the second embodiment of the present invention is similar to the first embodiment of the second embodiment, except that: in the second embodiment of the second embodiment, the metal supporting framework 22 is made by laser cutting heat setting, i.e. the sealing part 221, the connecting part 223 and the anchoring part 225 are all made by laser cutting heat setting. Wherein the sealing portion 221 is located at a proximal end position, and further comprises a grid frame 2212 and a connecting end 2215 formed by cutting; connection end 2215 is identical in location and function to the first embodiment. The connecting part 223 is positioned in the middle area of the metal supporting framework 22, the first electrode 52 is arranged on the connecting part 223, and the arrangement of the first electrode 52 is the same as that of the embodiment 1; anchor portion 225 is located at the distal end of metal support skeleton 22 and includes a cut-out anchor body 2252, anchor body 2252 having an anchor barb 2255 disposed on an outer wall surface thereof, anchor barb 2255 being of unitary construction with anchor body 2252. The insulation process between the first electrode 52 and the metal supporting framework 22 is the same as that of the first embodiment, and is not repeated herein. Anchor body 2252 of anchor portion 225 is frustoconical in configuration, i.e., the distal end of anchor portion 225 tapers inwardly to form a distal opening having a diameter less than the diameter of the proximal opening of anchor portion 225.

In other embodiments, the outer surface of the ablation occlusion device 100 may also be tapered or spherical.

Referring to fig. 11 and 12 together, fig. 11 is a schematic structural view of an ablation occlusion device according to a third embodiment of the present invention; fig. 12 is a diagram illustrating a state where the ablation occlusion device according to the third embodiment of the present invention is released in the left atrial appendage. The utility model discloses the structure of the ablation plugging device that the third embodiment provided is similar with the structure of the first embodiment, and the difference lies in: in the third embodiment, the ablation occlusion device 100 also includes a sealing portion 221, a connecting portion 223, and an anchoring portion 225, the sealing portion 221 and the connecting portion 223 are connected by a connecting member 60, and the connecting portion 223 and the anchoring portion 225 are integrally formed. Namely, the metal supporting framework 22 of the ablation occlusion device 100 has a double-disk structure including a proximal disk and a distal disk. The proximal and distal discs are connected by a connector 60. Wherein the proximal disc is formed by weaving and heat setting nickel-titanium wires to form a sealing part 221; the telecentric plate comprises a connecting part 223 and an anchoring part 225, and is also formed by nickel titanium weaving and shaping.

The mesh frame 2212 of the sealing portion 221 is used for sealing the entrance 306 of the left atrial appendage 305, and the mesh frame 2212 is matched with the entrance 306 of the left atrial appendage 305 in shape. As shown in fig. 12, in the present embodiment, the sealing portion 221 is pressed on the entrance 306 of the left atrial appendage 305, the diameter of the sealing portion 221 is slightly larger than the inner diameter of the entrance 306 of the left atrial appendage 305, and the grid frame 2212 adopts a disc-shaped structure with a short axial length, so that the grid frame 2212 can directly seal the entrance 306.

One or more layers of flow-blocking films 2214 are arranged in the grid structure 2212, and a connecting end 2215 is arranged on the proximal end face of the sealing part 221; the obstruction film 2214 may be disposed in the sealing portion 221, or a layer of polymer obstruction film 2214 may be coated on the outer surface of the sealing portion 221, and the obstruction film 2214 is preferably a PET or PTFE film. The connecting end 2215 is located at the center of the proximal disc surface of the grid structure 2212 and is used for connecting the conveyor.

The connecting portion 223 is located the telecentric plate proximal end, and the connecting portion 223 includes the netted net grid framework 2232 of ring, the outer wall surface of grid framework 2232 is fixed with first electrode 52, first electrode 52 is the incessant annular electrode of single circle setting. At least the outer wall surface of the first electrode 52 in contact with the mesh frame 2232 is insulated in the same manner as in example 1.

Anchor portion 225 is located at the distal end of the distal end disk and includes an anchor body 2252, a resistive membrane 2254, anchors 2255, and a closure 2257. The perimeter of the flow resistance membrane 2254 is secured within the anchor body 2252 by stitching.

The grid structure 2212 of the sealing part 221 and the grid frame 2232 of the connecting part 223 are connected together by the connecting part 60, and may be connected together by welding or pressing. The connecting member 60 is a columnar structure made of a conductive metal material, and the connecting member 60 is disposed between the center of the end surface of the proximal end of the connecting portion 223 and the center of the end surface of the distal end of the sealing portion 221. In this embodiment, the second electrode of the ablation occlusion device 100 is the mesh frame 2232 of the connection portion 223, that is, the mesh frame 2232 is connected to the lead 53 through the connector 60 and the connection end 2215, and the lead 53 connected to the connection end 2215 is directly grounded.

Referring to fig. 13, fig. 13 is a schematic structural view of a first embodiment of an ablation occlusion device according to a fourth embodiment of the present invention. The structure of the first embodiment of the ablation occlusion device provided by the fourth embodiment of the present invention is similar to that of the third embodiment, except that: in the first implementation of the fourth embodiment, the ablation occluding device 100 also includes a sealing portion 221, a connecting portion 223, and an anchoring portion 225. The sealing part 221 and the connecting part 223 are integrated, and the connecting part 223 and the anchoring part 225 are connected through a connecting piece 60; the sealing part 221 comprises a mesh grid frame 2212 of a disc net, the mesh grid frame 2212 is used for being attached to and pressed on an inlet of the left atrial appendage, the connecting part 223 comprises a mesh grid frame 2232, the mesh grid frame 2232 can be inserted into the inlet of the left atrial appendage, namely, the inlet of the left atrial appendage and the neck of the left atrial appendage are simultaneously sealed by the integrated structure of the sealing part 221 and the connecting part 223. The proximal end of the grid frame 2232 is open and connected to the grid frame 2212, and the grid frame 2232 is folded away and connected to the proximal end of the anchor 225 by the connector 60. The shape of the grid frame 2212 is matched with that of the entrance of the left atrial appendage, and the shape of the grid frame 2232 is matched with that of the neck of the left atrial appendage. The diameter of the grid frame 2212 is slightly larger than the inner diameter of the entrance of the left atrial appendage, and the grid frame 2212 adopts a disk-shaped structure with a short axial length, and the disk-shaped structure can directly cling to the surface of the entrance of the left atrial appendage facing the left atrium.

Specifically, the ablation occlusion device is of a double-disc structure and comprises a proximal disc and a distal disc. The proximal and distal discs are connected by a connector 60. Wherein the proximal disc comprises a sealing portion 221 and a connecting portion 223; the distal disc is an anchor 225; the proximal disc and the distal disc are both formed by nickel-titanium wire weaving and heat setting.

The integral structure of the sealing part 221 and the connecting part 223 is in a bottle plug shape, that is, the diameter of the sealing part 221 is larger than that of the connecting part 223, and the diameter of the connecting part 223 gradually decreases from the proximal end to the distal end to form a frustum shape.

The connecting portion 223 is located at the distal end of the proximal disc, and a first electrode 52 is fixed on the outer wall surface of the grid frame 2232 of the connecting portion 223, wherein the electrode 52 is an uninterrupted annular electrode arranged in a single circle. At least the surface of the electrode 52 in contact with the mesh frame 2232 is insulated.

The anchor body 2252 of the anchor portion 225 is cylindrical in structure. Both ends of the far end and the near end of the cylindrical structure are closed to form a cylindrical structure.

The grid structure 2212 of the connecting portion 223 and the grid frame 2232 of the anchoring portion 225 are connected together by the connecting member 60, and may be connected together by welding or pressing. The connecting member 60 is a columnar structure made of a conductive metal material, and the connecting member 60 is disposed between the center of the end surface of the distal end of the connecting portion 223 and the center of the end surface of the proximal end of the anchoring portion 225. In this embodiment, the second electrode of the ablation occlusion device 100 is a metal frame composed of the mesh frame 2212 of the sealing portion 221 and the mesh frame 2232 of the connecting portion 223, that is, the metal frame is electrically connected to the lead 53 through the connecting end 2215, and the lead 53 connected to the connecting end 2215 is directly grounded.

Referring to fig. 14, fig. 14 is a schematic structural view of a second embodiment of an ablation occlusion device of a fourth embodiment. The structure of the second embodiment of the ablation occlusion device provided by the fourth embodiment of the present invention is similar to the structure of the first embodiment of the fourth embodiment, except that: first electrode 52 is disposed at a proximal end of an outer wall surface of anchor portion 225, i.e., first electrode 52 is fixed to an outer wall surface of anchor body 2252 of anchor portion 225, and first electrode 52 is an uninterrupted ring-shaped electrode disposed in a single turn. The outer wall surface of the first electrode 52 in contact with the anchor body 2252 is subjected to an insulation treatment, which may be the same as in embodiment 1.

The connecting member 60 is a columnar structure made of a conductive metal material, and the connecting member 60 is disposed between the center of the end surface of the distal end of the connecting portion 223 and the center of the end surface of the proximal end of the anchoring portion 225. In this embodiment, the second electrode of the ablation occlusion device is the anchor body 2252 of the anchor portion 225, i.e., the anchor body 2252 is electrically connected to the lead 53 through the connector 60 and the connection end 2215, and the lead 53 connected to the connection end 2215 is directly connected to the ground.

Referring to fig. 15, fig. 15 is a schematic structural view of an ablation occlusion device according to a fifth embodiment of the present invention; the structure of the ablation occlusion device provided by the fifth embodiment of the present invention is similar to that of the first embodiment of the fourth embodiment, except that: in the fifth embodiment, the anchor body 2252 is a folded structure, which is formed by gradually folding back from the center of the distal end of the connecting portion 223 to the outer side in the distal direction, and the anchor spurs 2255 are uniformly arranged around the outer wall of the folded structure. Specifically, the anchoring portion 225 is a distal opening structure formed by knitting or laser cutting, an inner supporting section is formed by extending the connecting piece 60 at the distal center of the connecting portion 223 in the distal direction, and then the anchoring portion 225 is formed by reversely folding. The turnover structure is converged towards the center after being turned over, so that a closed structure is formed.

In other embodiments, the fold-over structures of the fifth embodiment do not converge toward the center after folding over, forming an anchor body with a proximal opening. The proximal opening faces the connecting portion 223, and the proximal end of the anchoring portion 225 is spaced from the diameter of the connecting portion 223. The proximal opening can be divided into a half-opening structure which is contracted towards the center and a full-opening structure which is not contracted towards the center.

Referring to fig. 16, fig. 16 is a schematic structural view of a first embodiment of an ablation occlusion device according to a sixth embodiment of the present invention. The structure of the first embodiment of the ablation occlusion device provided by the sixth embodiment of the present invention is similar to that of the first embodiment, except that: the ablation member in the sixth embodiment is different from the ablation member in the first embodiment, in the first implementation manner of the sixth embodiment, the ablation member 50 includes at least one first electrode 52 and at least one second electrode 56, the at least one first electrode 52 and the at least one second electrode 56 are disposed on the outer wall of the metal supporting framework 22 at intervals, the at least one first electrode 52 is electrically connected to the radio frequency power source through a conducting wire 53, and the at least one second electrode 56 is directly grounded through the conducting wire 53. The first electrode 52 and the second electrode 56 may have the same or different structures, in this embodiment, the first electrode 52 and the second electrode 56 are both annular electrodes, both the first electrode 52 and the second electrode 56 are circumferentially disposed on the outer wall surface of the metal supporting skeleton 22, and both the first electrode 52 and the second electrode 56 and the metal supporting skeleton 22 are subjected to an insulating treatment. Specifically, the first electrode 52 and the second electrode 56 are spaced in parallel, and are attached to the outer wall surface of the grid frame 2232 along the circumferential direction of the connecting portion 223, and the first electrode 52, the second electrode 56 and the grid frame 2232 are insulated by coating an insulating coating on the outer surface of the metal supporting skeleton 22 contacting with the first electrode 52 and the second electrode 56, or inserting an insulating sleeve on the metal wire of the metal supporting skeleton 22, where the insulating sleeve wraps the outer surface of the metal wire of the metal supporting skeleton 22, and the coating or the sleeve may be selected from FEP/ETFE/PFA.

In the present embodiment, the metal supporting framework 22 is only used as a supporting framework, that is, the metal supporting framework 22 is not grounded, but directly grounded through the second electrode 56, the first electrode 52 is connected to the radio frequency power source, so that a current loop is formed between the first electrode 52 and the second electrode 56, that is, the current only flows through the tissue of the left atrial appendage 305 between the first electrode 52 and the second electrode 56, so as to prevent the current from damaging other tissues of the human body, and the radio frequency energy can be concentrated on the first electrode 52 and the second electrode 56 for ablation, thereby achieving a better ablation effect.

In other embodiments, two or more circles of ring-shaped first electrodes 52 and/or second electrodes 56 are circumferentially disposed on the outer wall surface of the metal supporting skeleton 22, these first electrodes 52 and/or second electrodes 56 may be connected or discontinuous, these first electrodes 52 or second electrodes 56 may also be disposed in parallel or staggered in the axial direction of the metal supporting skeleton 22; the first electrodes 52 and the second electrodes 56 may be alternatively arranged, and when the electrodes are alternatively arranged, the contact position between the first electrodes 52 and the second electrodes 56 is insulated.

In other embodiments, the shape of the first electrode 52 may be as shown in the first embodiment, i.e., the first electrode 52 may be a connected or interrupted ring-shaped electrode, a dot-shaped electrode, a rod-shaped electrode, or the like.

Referring to fig. 17, fig. 17 is a schematic structural view of a second embodiment of an ablation occlusion device according to a sixth embodiment. The structure of the second embodiment of the ablation occlusion device provided in the sixth embodiment of the present invention is similar to the structure of the first embodiment of the sixth embodiment, except that: the metal supporting skeleton 22 is provided with an insulating coating 54 which isolates the first electrode 52 and the second electrode 56 from the metal supporting skeleton 22 at least at the outer wall surface contacting the first electrode 52 and the second electrode 56. Specifically, an annular insulating coating 54 is wrapped between the outer wall surface of the mesh frame 2212 of the connection portion 223 and the contact surfaces of the first electrode 52 and the second electrode 56. The insulating coating 54 is effective in preventing current from flowing into the metal support frame 22, which can cause energy loss and damage to other body tissues.

Referring to fig. 18, fig. 18 is a schematic structural view of a third embodiment of an ablation occlusion device according to a sixth embodiment. The structure of the third embodiment of the ablation occlusion device provided in the sixth embodiment of the present invention is similar to the structure of the first embodiment of the sixth embodiment, except that: the metal supporting frame 22 is wrapped with a layer of insulating coating 57 on the entire outer wall surface, that is, the outer wall surfaces of the sealing portion 221, the connecting portion 223 and the anchoring portion 225 are wrapped with the insulating coating 57, and the first electrode 52 and the second electrode 56 may be circumferentially disposed on the outer wall surface of the sealing portion 221, the outer wall surface of the connecting portion 223 or the outer wall surface of the anchoring portion 225 at intervals. In this embodiment, the first electrode 52 and the second electrode 56 are disposed on the outer wall surface of the connection portion 223.

In this embodiment, the insulating coating 57 may be a spherical coating, and the spherical coating means that at least the distal end face and the distal end portion of the metal supporting framework 22 form an annular package, and the outer surface of the metal supporting framework 22 is completely or partially wrapped in the insulating coating 57; in this embodiment, the surface of the insulating coating 57 is a dense structure without holes, which can achieve effective insulation, and when the insulating coating 57 is also disposed at the proximal end of the sealing portion 221, the insulating coating 57 is disposed here as a blocking member, which serves to block thrombus. Meanwhile, the choke film in the sealing portion 221 may or may not be provided. On the other hand, the insulating coating 57 between the first electrode 52 and the second electrode 56 and the metal supporting framework 22 can be used as an insulating barrier between the electrodes and the metal supporting framework 22, so that the radio frequency energy on the electrodes is prevented from being transmitted to the metal supporting framework 22, the radio frequency energy can be concentrated between the first electrode 52 and the second electrode 56 on the inner wall of the left atrial appendage 305, the radio frequency energy on the electrodes is further prevented from being lost, the ablation efficiency is improved, and other tissues of the body are prevented from being damaged.

In other embodiments, the first electrode 52 may be disposed on the outer wall surface of the connection portion 223, and the second electrode 56 may be disposed on the outer wall surface of the sealing portion 221 or the outer wall surface of the anchoring portion 225; alternatively, the first electrode 52 may be disposed on the outer wall surface of the sealing portion 221, and the second electrode 56 may be disposed on the outer wall surface of the connecting portion 223 or the outer wall surface of the anchoring portion 225, or the like, that is, the first electrode 52 and the second electrode 56 may be disposed at any position of the outer wall surface of the metal supporting skeleton 22, and only the first electrode 52 and the second electrode 56 need to be attached to the inner wall of the left atrial appendage 305.

Referring to fig. 19, fig. 19 is a schematic structural view of a first embodiment of an ablation occlusion device according to a seventh embodiment of the present invention; the structure of the first embodiment of the ablation occlusion device provided by the seventh embodiment of the present invention is similar to that of the third embodiment, except that: the ablating member of the seventh embodiment is different from the ablating member of the third embodiment, in the seventh embodiment, the ablating member 50 includes at least one first electrode 52 and at least one second electrode 56, and the at least one first electrode 52 and the at least one second electrode 56 are disposed on the outer wall of the metal supporting framework 22 at intervals. The at least one first electrode 52 is electrically connected to the radio frequency power source through the lead 53, the first electrode 52 is used as an ablation electrode, and the at least one second electrode 56 is directly grounded through the lead 53.

In the present embodiment, the first electrode 52 and the second electrode 56 are both annular electrodes, the first electrode 52 and the second electrode 56 are both circumferentially provided on the outer wall surface of the mesh frame 2232 of the connection portion 223, and both the first electrode 52 and the second electrode 56 are insulated from the mesh frame 2232. The insulating treatment is performed by coating an insulating coating on the outer surface of the metal supporting skeleton 22 contacting the first electrode 52 and the second electrode 56, or inserting an insulating sleeve on the metal wire of the metal supporting skeleton 22, wherein the insulating sleeve is wrapped on the outer surface of the metal wire of the metal supporting skeleton 22, and the coating or sleeve material may be FEP/ETFE/PFA.

In the present embodiment, the metal supporting framework 22 is only used as a supporting framework, that is, the metal supporting framework 22 is not grounded, but grounded through the second electrode 56, the first electrode 52 is connected to the radio frequency power source, so that a current loop is formed between the first electrode 52 and the second electrode 56, that is, current only flows between the first electrode 52 and the second electrode 56, so that radio frequency energy can be concentrated on the first electrode 52 on the inner wall of the left atrial appendage 305, the radio frequency energy on the electrodes is prevented from being lost, the ablation efficiency is improved, and other tissues of the body are prevented from being damaged.

In other embodiments, two or more circles of ring-shaped first electrodes 52 and/or second electrodes 56 are circumferentially disposed on the outer wall surface of the grid frame 2232, the first electrodes 52 and/or second electrodes 56 may be connected or disconnected, and the first electrodes 52 or second electrodes 56 may also be disposed in parallel or staggered in the axial direction of the metal supporting skeleton 22; the first electrodes 52 and the second electrodes 56 may be alternatively arranged, and when the electrodes are alternatively arranged, the contact position between the first electrodes 52 and the second electrodes 56 is insulated.

In other embodiments, first electrode 52 and/or second electrode 56 may also be disposed on an outer wall of anchor body 2252 of anchor portion 225.

Referring to fig. 20, fig. 20 is a schematic structural view of a first embodiment of an ablation occlusion device according to an eighth embodiment of the present invention; the structure of the first implementation way of the ablation occlusion device provided by the eighth embodiment of the present invention is similar to that of the fourth embodiment, except that: the ablating member of the first embodiment is different from the ablating member of the fourth embodiment, in the first embodiment of the eighth embodiment, the ablating member 50 includes at least one first electrode 52 and at least one second electrode 56, the at least one first electrode 52 and the at least one second electrode 56 are disposed on the outer wall surface of the connecting portion 223 at intervals, the at least one first electrode 52 is electrically connected to the rf power source through a conducting wire 53, and the at least one second electrode 56 is grounded through the conducting wire 53. The first electrode 52 and the second electrode 56 are both annular electrodes, the first electrode 52 and the second electrode 56 are both circumferentially disposed on the outer wall surface of the mesh frame 2232, and both the first electrode 52 and the second electrode 56 are insulated from the mesh frame 2232. Specifically, the first electrode 52 and the second electrode 56 are spaced in parallel, and are attached to the outer wall surface of the mesh frame 2232 along the circumferential direction of the connecting portion 223, and the first electrode 52, the second electrode 56, and the mesh frame 2232 are insulated from each other in the same manner as the fourth embodiment.

In other embodiments, the anchor body 2252 has at least one first electrode 52 and at least one second electrode 56 disposed circumferentially on an outer wall surface thereof, with the first electrode 52 being spaced from the second electrode 56.

In other embodiments, the first electrode 52 and/or the second electrode 56 having a ring shape of two or more turns are disposed on the outer wall surface of the mesh frame 2232 of the connecting portion 223 or the outer wall surface of the anchoring body 2252, and these first electrode 52 and/or second electrode 56 may be connected or interrupted.

Referring to fig. 21, fig. 21 is a schematic structural view of a second embodiment of an ablation occlusion device according to an eighth embodiment; the structure of the first embodiment of the ablation occlusion device provided by the eighth embodiment of the present invention is similar to the structure of the second embodiment of the eighth embodiment, except that: in a second implementation manner of the eighth embodiment, the first electrode 52 is disposed on the outer wall surface of the anchor main body 2252, the second electrode 56 is disposed on the outer wall surface of the grid frame 2232 of the connecting portion 223, the first electrode 52 is electrically connected to the radio frequency source through a wire, and the second electrode 52 is grounded through a wire 53. Specifically, first electrode 52 is an uninterrupted ring electrode, with first electrode 52 circumferentially disposed on a proximal end of the outer wall surface of anchor body 2252, and second electrodes 56 are each intermittent ring electrodes, with second electrodes 56 circumferentially disposed on a distal end of the outer wall surface of mesh frame 2232. The first electrode 52 and the anchor body 2252 are insulated from each other, and the second electrode 56 and the connecting portion 223 are insulated from each other in the same manner as in the fourth embodiment.

In other embodiments, the first electrode 52 may be disposed on an outer wall surface of the mesh frame 2232 of the connection part 223, the first electrode 52 and the connection part 223 being insulated from each other, and the second electrode 56 may be disposed on an outer wall surface of the anchor body 2252, the second electrode 56 and the anchor body 2252 being insulated from each other. The first electrode 52 is electrically connected to a radio frequency source through a wire, and the second electrode 52 is grounded through a wire.

In other embodiments, the first and

second electrodes

52 and 56 may be disposed on the outer wall surface of the anchor body 2252 at intervals, and the first and

second electrodes

52 and 56 are insulated from the anchor body 2252. The first electrode 52 is electrically connected to a radio frequency source through a wire, and the second electrode 52 is grounded through a wire.

Referring to fig. 22, fig. 22 is a schematic structural view of an ablation occlusion device according to a ninth embodiment of the present invention. The utility model discloses the structure of the ablation plugging device that the ninth embodiment provided is similar to the first implementation mode of sixth embodiment, and the difference lies in: in the ninth embodiment, the ablating member 50 includes two first electrodes 52 and a second electrode 56, and the two first electrodes 52 are spaced apart from each other and disposed on the outer wall of the metal supporting framework 22. The second electrode 56 is disposed on the outer wall of the metal supporting frame 22, the second electrode 56 is located between the two first electrodes 52, and the second electrode 56 is spaced apart from the two first electrodes 52. The two first electrodes 52 and the second electrode 56 are insulated from the metal supporting frame 22. The two first electrodes 52 are electrically connected to the radio frequency source through wires 53, and the second electrodes 52 are grounded through wires. Specifically, the two first electrodes 52 and the two second electrodes 56 are circumferentially provided on the outer wall surface of the mesh frame 2232 of the connection portion 223.

In the present embodiment, the metal supporting frame 22 is used only as a supporting frame, that is, the metal supporting frame 22 is not grounded, but grounded through the second electrode 56, and the two first electrodes 52 are respectively connected to the rf power source, so as to form two sets of current loops, that is, each first electrode 52 and the second electrode 56 form a circuit loop. When the ablation device is used, the impedance values between the first electrode 52 and the second electrode 56 of the two sets of current loops can be detected respectively, the impedance values of the two sets of current loops are compared, and the set of current loop with the larger impedance value is selected to provide energy for ablation treatment. Since the larger the attaching area of the first electrode 52 and the inner wall of the left atrial appendage 305 is, the larger the impedance value in the current loop is, the probability of successful ablation can be increased by selecting the current loop with the larger attaching area of the first electrode 52 and the inner wall of the left atrial appendage 305 for ablation, so as to achieve a better ablation effect.

In other embodiments, more than two first electrodes 52 may be disposed on the outer wall of the metal supporting skeleton 22, each pair of first electrodes 52 is a ring-shaped electrode disposed along the outer wall surface of the metal supporting skeleton 22, and the second electrode 56 is insulated from the metal supporting skeleton 22, and the second electrode 56 is spaced from each first electrode 52. Each first electrode 52 is electrically connected to a radio frequency power source, and the second electrode 56 is grounded through a wire 53. The first electrodes 52 and the second electrodes 56 form at least two sets of current loops, and when in use, the impedance values of the current loops of each set are detected respectively, the impedance values of the current loops of each set are compared, and the current loop of the set with the largest impedance value is selected to provide energy for ablation treatment.

In other embodiments, two or more first electrodes 52 and two or more second electrodes 56 may be respectively disposed on the outer wall of the metal supporting framework 22, each first electrode 52 is connected to the rf power source, each second electrode 56 is grounded through the conducting wire 53, and each first electrode 52 and the corresponding second electrode 56 form a current loop, i.e., form two or more sets of current loops. When the ablation device is used, the impedance values of all the current loops are detected respectively, the impedance values of all the current loops are compared, and the current loop with the largest impedance value is selected to provide energy for ablation treatment.

The above is an implementation manner of the embodiments of the present invention, and it should be noted that, for those skilled in the art, a plurality of improvements and decorations can be made without departing from the principles of the embodiments of the present invention, and these improvements and decorations are also considered as the protection scope of the present invention.

Claims

1. The utility model provides an melt plugging device, its is including the plugging piece that is used for sealing left auricle, its characterized in that, melt plugging device still including melting the piece, it includes first electrode and second electrode to melt the piece, first electrode set up in on the outer wall of plugging piece, first electrode passes through wire electric connection in radio frequency power supply, the second electrode passes through wire ground connection, first electrode with the second electrode forms the electric current return circuit in order to receive the inner wall of radio frequency power supply melts the inner wall of left auricle.

2. The ablation occlusion device of claim 1, wherein the first electrode is insulated from the occlusion piece.

3. The ablation occlusion device of claim 2, wherein the occlusion piece comprises a metal support frame attached to an inner wall of the left atrial appendage, the metal support frame serving as a second electrode of the ablation piece, the metal support frame being grounded via a wire.

4. The ablation occlusion device of claim 3, wherein the first electrode is disposed on an outer wall surface of the metal support frame, the first electrode being insulated from the metal support frame.

5. The ablation occlusion device of claim 3, wherein the first electrode is a ring-shaped electrode having at least one continuous or discontinuous turn disposed along the outer wall surface of the metal supporting skeleton.

6. The ablation occlusion device of claim 3, wherein the first electrode comprises a plurality of point-like electrodes or strip-like electrodes arranged on the outer wall surface of the metal supporting framework, the plurality of point-like electrodes encircle the metal supporting framework for a circle, and the plurality of point-like electrodes are connected in series through a lead and then are connected to a radio frequency power supply.

7. The ablation occlusion device of claim 4, wherein the first electrode is insulated from the metal support skeleton by an insulating coating, or an insulating sleeve.

8. The ablation occlusion device of claim 7, wherein the outer wall of the metal support skeleton is coated with an insulating coating or provided with an insulating covering film at least at the connection with the first electrode.

9. The ablation occlusion device of claim 8, wherein the metal support framework is provided with an insulating coating isolating the first electrode from the metal support framework at least at an outer wall surface in contact with the first electrode.

10. The ablation occlusion device of claim 1, wherein the first and second electrodes are each at least one turn of electrode disposed along an outer wall surface of the occlusion member.

11. The ablation occlusion device of claim 10, wherein the first electrode is spaced from the second electrode, the first and/or second electrodes being insulated from the occlusion member.

12. The ablation occlusion device of claim 2, wherein the number of the first electrodes is two, and both of the first electrodes are arranged in at least one circle along the outer wall surface of the occlusion piece, the second electrode is insulated from the occlusion piece, and is spaced from both of the first electrodes, and the two first electrodes and the second electrode form two sets of current loops.

13. The ablation occlusion device of claim 2, wherein the number of the first electrodes is two or more, each first electrode is an electrode arranged in at least one circle along the outer wall surface of the occlusion piece, the second electrode is insulated from the occlusion piece, the second electrode is spaced apart from each first electrode, and the first electrodes and the second electrodes form two or more sets of current loops.

14. The ablation occlusion device of claim 2, wherein the number of the first electrodes is two or more, each first electrode is an electrode arranged at least one circle along the outer wall surface of the occlusion piece, the number of the second electrodes is the same as the number of the first electrodes, each second electrode is insulated from the occlusion piece, each first electrode is spaced from the corresponding second electrode, and the first electrodes and the corresponding second electrodes form two or more sets of current loops.

15. The ablation occlusion device of any of claims 10-14, wherein the occlusion member comprises a metal supporting framework attached to an inner wall of the left atrial appendage, and the first and second electrodes are ring electrodes disposed in at least one continuous or discontinuous loop along an outer wall of the metal supporting framework; or a plurality of point electrodes are arranged on the outer wall surface of the metal supporting framework, the plurality of point electrodes surround the metal supporting framework for a circle, and the plurality of point electrodes are connected in series through a lead and then are connected to a radio frequency power supply; or a plurality of strip electrodes are arranged on the outer wall surface of the metal supporting framework, the plurality of strip electrodes surround the metal supporting framework for a circle, and the plurality of strip electrodes are connected in series through a lead and then are connected to a radio frequency power supply.

16. The ablation occlusion device of claim 15, wherein the first and second electrodes may be identical or different in configuration.

17. The ablation occlusion device of claim 1, wherein the occlusion piece comprises a connecting portion, an outer wall surface of the connecting portion is fitted to an inner wall of the left atrial appendage, and the first electrode and/or the second electrode are disposed on an outer wall surface of the connecting portion.

18. The ablation occlusion device of claim 1, wherein the occlusion piece comprises an anchoring portion having an outer wall surface that conforms to an inner wall of the left atrial appendage, the first electrode and/or the second electrode being disposed on the outer wall surface of the anchoring portion.

19. The ablation occlusion device of claim 1, wherein the occlusion member comprises a connecting portion and an anchoring portion at a distal end of the connecting portion, outer wall surfaces of the connecting portion and the anchoring portion are fitted to an inner wall surface of the left atrial appendage, the first electrode is disposed on an outer wall surface of the connecting portion or the anchoring portion, and the second electrode is disposed on an outer wall surface of the anchoring portion or the connecting portion.

20. The ablation occlusion device of claim 1, wherein the occlusion piece comprises a sealing portion for closing an entrance to the left atrial appendage, an anchoring portion distal to the sealing portion, and a connecting portion between the sealing portion and the anchoring portion for positioning the ablation occlusion device.