CN210470814U - Program cooling box for storing freezing bag - Google Patents
Program cooling box for storing freezing bag Download PDFInfo
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- CN210470814U CN210470814U CN201921190469.0U CN201921190469U CN210470814U CN 210470814 U CN210470814 U CN 210470814U CN 201921190469 U CN201921190469 U CN 201921190469U CN 210470814 U CN210470814 U CN 210470814U
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Abstract
The utility model discloses a deposit procedure cooling box of cryopreserving bag, including box body and the lid that is the cuboid form, one side of box body is seted up flutedly, has seted up slot and the interlayer that a plurality of even equidistance were crisscross to be set up in the recess, and open-ended one side center department is kept away from to every interlayer and has seted up the through-hole, and the interlayer is kept away from open-ended one side and is provided with solid-state alloy hot core, and it has cryopreserving bag protection box to peg graft in the slot, is provided with the cryopreserving bag in the cryopreserving bag protection box, and one side of lid is provided with the arch. The utility model puts the freezing bag into the cell freezing box horizontally, so that the thickness is uniform, and the freezing and recovery are facilitated due to uniform heating; the design of the interlayer between the slots of the cryopreservation bag and the solid alloy hot core with holes on one side of the cryopreservation bag enables the cell cryopreservation liquid to be uniformly frozen and the temperature reduction range to be stable; the insulating cross-linked closed-cell polyethylene foam plastic is used as a main material of the cryopreservation box to realize slow cooling.
Description
Technical Field
The utility model relates to a cell seals up deposits equipment technical field, specifically is a deposit procedure cooling box of cryopreserving bag.
Background
Cell therapy is a new disease treatment technology emerging in the medical industry at present, and means that certain cells with specific functions are obtained through biotechnology or are cultured through direct extraction, in-vitro amplification and special activation, so that the cells have treatment effects of enhancing immunity, killing pathogens and tumor cells, promoting regeneration of tissues and organs, adjusting metabolic balance, recovering body health and the like, and the purpose of treating diseases is achieved. The cell intervention treatment has the unique advantages of low side effect, good curative effect and the like, and plays an important role in the clinical treatment of diseases such as tumor, immunodeficiency and the like. Therapeutic cells mainly comprise immune cells and stem cells, and particularly, the large amount of frozen immune cells is always a difficult problem due to the large medical intervention dosage of the immune cells. The freezing storage of cells is a very critical step, and the activity and the curative effect of the cells are related.
There are two methods for the conventional bulk cryopreservation of stem cells and immune cells: one is to inject the cell freezing solution into the freezing bag, put the freezing bag at 4 ℃ for 30-60min, -20 ℃ for 1-2h, -80 ℃ overnight, and then transfer to liquid nitrogen for long-term storage; the other method is to inject the cell freezing solution into the freezing bag, then put the freezing bag into a program cooling instrument to realize gradient cooling, and put the freezing bag into liquid nitrogen for long-term storage. However, the former is complicated to operate, the latter program cooling instrument is expensive, the consumption of liquid nitrogen is large, the sample processing cost is high, the existing cell freezing box is low in cost and simple to operate, but only low-volume cell freezing liquid such as 2ml and 5ml can be put in the cell freezing box, and a freezing bag cannot be placed in the cell freezing box. In view of this, we provide a programmed cooling box for storing frozen storage bags.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a deposit procedure cooling box of cryopreserving bag to it presents cell cryopreserving box low cost and easy operation now to solve among the above-mentioned background art, but can only put into low volume cell cryopreserving liquid such as 2ml, 5ml, can not place the problem of cryopreserving bag.
In order to achieve the above object, the utility model provides a following technical scheme:
the utility model provides a deposit procedure cooling box of cryopreserving bag, includes box body and the lid that is the cuboid form, one side of box body is seted up flutedly, set up slot and interlayer that a plurality of even equidistance are crisscross setting in the recess, every the interlayer is kept away from open-ended one side center department and is seted up the through-hole, the interlayer is kept away from open-ended one side is provided with solid-state alloy hot core, it has cryopreserving bag protection box to peg graft in the slot, be provided with the cryopreserving bag in the cryopreserving bag protection box, one side of lid is provided with the arch, a plurality of even equidistance are crisscross setting slot and interlayer also seted up in the arch.
Preferably, the side area of the box body is matched with the side area of the box cover in size.
Preferably, the protrusion corresponds to the groove in position and is matched with the groove in size, and the protrusion is matched with the groove in an inserted manner.
Preferably, the groove corresponds to the slot and the interlayer arranged on the protrusion in position and is matched with the groove in size.
Preferably, the freezing bag protection box is a hollow uncovered cuboid structure.
Preferably, the cryopreservation bag protection box is matched with the slot in size, and the cryopreservation bag protection box is matched with the slot in an inserted manner.
Preferably, the box body and the box cover are both provided with heat insulation layers, and the heat insulation layers are made of insulating cross-linked closed-cell polyethylene foam plastics.
Compared with the prior art, the beneficial effects of the utility model are that: the program cooling box for storing the freezing bag solves the problem that the cost for freezing and storing cells by using a program cooling instrument in the prior art is high, and solves the problem that the traditional temperature gradient cooling operation is complicated; the technical problem that the cell cryopreservation box can not be used for placing the cryopreservation bag is solved, the cost is low, and the operation is simple; the box body and the box cover are integrally designed, so that the service life is long, the performance is stable, the convex-concave clamping grooves are connected and sealed, and the operation is simple; the freezing bag is horizontally placed to ensure uniform thickness, and the freezing bag is uniformly heated to be beneficial to freezing and recovery; the design of the interlayer between the slots of the cryopreservation bag and the solid alloy hot core with holes on one side of the cryopreservation bag enables the cell cryopreservation liquid to be uniformly frozen and the temperature reduction range to be stable; the insulating cross-linked closed-cell polyethylene foam plastic is used as a main material of the cryopreservation box to realize slow cooling.
Drawings
Fig. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic cross-sectional view of the box body of the present invention;
FIG. 3 is a schematic cross-sectional view of the lid of the present invention;
FIG. 4 is a schematic sectional view of the present invention;
FIG. 5 is a left side view of the box body of the present invention;
fig. 6 is a right side view schematic diagram of the box body of the present invention.
In the figure: 1. a box body; 2. a box cover; 3. a slot; 4. an interlayer; 5. a through hole; 6. a solid alloy hot core; 7. protecting the freezing storage bag; 8. freezing and storing the bags; 9. a groove; 10. a protrusion; 11. a heat preservation and insulation layer.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
In the description of the present invention, it is to be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and to simplify the description, but do not indicate or imply that the device or element referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore should not be construed as limiting the present invention.
Referring to fig. 1-6, the present invention provides the following technical solutions:
the utility model provides a deposit procedure cooling box of freezing bag, as shown in figure 1, including box body 1 and the lid 2 that is the cuboid form, recess 9 has been seted up to one side of box body 1, as shown in figure 2, it is crisscross slot 3 and the interlayer 4 that sets up to have a plurality of even equidistance to be seted up in recess 9, every interlayer 4 keeps away from open-ended one side center department and has seted up through-hole 5, as shown in figure 5 and figure 6, set up the through-hole 5 corresponding with box body 1 position on the lid 2, size looks adaptation, interlayer 4 keeps away from open-ended one side and is provided with solid alloy heat core 6, it has freezing bag protection box 7 to peg graft in the slot 3, be provided with freezing bag 8 in the freezing bag protection box 7, one side of lid 2 is provided with arch 10, as shown in figure 3, arch 10 has also seted up a plurality of even equid.
Furthermore, as shown in fig. 4, the side area of the box body 1 is matched with the side area of the box cover 2, so that the structure is more stable.
Specifically, the protrusion 10 corresponds to the groove 9 in position and has a size suitable for the groove 9, and the protrusion 10 is inserted into the groove 9. The groove 9 corresponds to the slot 3 and the interlayer 4 arranged on the bulge 10 in position and is matched with the groove in size, so that the sealing performance is improved.
It is worth to say that, the cryopreserving bag protection box 7 is the cuboid structure that is cavity uncovered, is convenient for place or take out cryopreserving bag 8, and cryopreserving bag protection box 7 and slot 3's size looks adaptation, and cryopreserving bag protection box 7 and slot 3 grafting cooperation, conveniently install cryopreserving bag protection box 7 or take out.
It is worth noting that the box body 1 and the box cover 2 are both provided with heat insulation layers 11, the heat insulation layers are made of insulation cross-linked closed-cell polyethylene foam plastics, the solid alloy hot core 6 is made of solid alloy, the interlayer 4 between the slot 3 and the freezing bag slot 3 and the solid alloy hot core with holes on one side are designed, and the cell freezing solution is uniformly frozen through the insulation cross-linked closed-cell polyethylene foam plastics on the periphery, so that the cell freezing solution is stably cooled in a range and slowly cooled, and the best freezing effect is achieved.
The program cooling box for storing the freezing storage bag has the advantages that the box body 1 and the box cover 2 are integrally designed, the service life is long, the performance is stable, the protrusion 10 and the groove 9 are plugged and sealed, and the operation is simple; the freezing bag 8 is horizontally placed to have uniform thickness, and is heated uniformly to be beneficial to freezing and recovery; the design of an interlayer 4 between the slots 3 of the cryopreservation bag and the slots and a solid alloy hot core 6 with a through hole 5 at one side of the interlayer make the cell cryopreservation liquid freeze uniformly and stably reduce the temperature; the insulating cross-linked closed-cell polyethylene foam plastic is used as a main material of the cryopreservation box to realize slow cooling.
The utility model discloses a deposit procedure cooling box of cryopreserving bag when using, operating personnel opens lid 2 earlier, will cryopreserve bag 8 and keep flat and go into cryopreserving bag protection box 7 in, and will cryopreserve bag protection box 7 inserts in proper order to cryopreserving bag slot 3 in, close lid 2, and the solid-state alloy hot core 6 of interlayer 4 design and one of which side band through-hole 5 between cryopreserving bag slot 3 and the slot 3 makes the cell cryopreserving liquid freeze evenly in the cryopreserving bag 8, and the range of stably cooling down.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It should be understood by those skilled in the art that the present invention is not limited by the above embodiments, and the description in the above embodiments and the description is only preferred examples of the present invention, and is not intended to limit the present invention, and that the present invention can have various changes and modifications without departing from the spirit and scope of the present invention, and these changes and modifications all fall into the scope of the claimed invention. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (7)
1. The utility model provides a deposit procedure cooling box of freezing bag which characterized in that: including box body (1) and lid (2) that are the cuboid form, one side of box body (1) is seted up flutedly (9), it is crisscross slot (3) and interlayer (4) that set up to have seted up a plurality of even equidistance in recess (9), every interlayer (4) are kept away from open-ended one side center department and have seted up through-hole (5), interlayer (4) are kept away from open-ended one side is provided with solid-state alloy hotcore (6), it has cryopreserved bag protection box (7) to peg graft in slot (3), be provided with cryopreserved bag (8) in cryopreserved bag protection box (7), one side of lid (2) is provided with arch (10), a plurality of even equidistance have also been seted up in arch (10) and are crisscross slot (3) and interlayer (4) that set up.
2. The programmed cooling box for storing frozen bags according to claim 1, wherein: the side area of the box body (1) is matched with the side area of the box cover (2) in size.
3. The programmed cooling box for storing frozen bags according to claim 1, wherein: the position of the protrusion (10) corresponds to that of the groove (9), the size of the protrusion is matched with that of the groove, and the protrusion (10) is matched with the groove (9) in an inserted manner.
4. The programmed cooling box for storing frozen bags according to claim 1, wherein: the groove (9) corresponds to the slot (3) and the interlayer (4) arranged on the bulge (10) in position and is matched with the size.
5. The programmed cooling box for storing frozen bags according to claim 1, wherein: the freezing bag protection box (7) is a hollow uncovered cuboid structure.
6. The programmed cooling box for storing frozen bags according to claim 1, wherein: the freezing and storing bag protection box (7) is matched with the size of the slot (3), and the freezing and storing bag protection box (7) is matched with the slot (3) in an inserting mode.
7. The programmed cooling box for storing frozen bags according to claim 1, wherein: the box body (1) and the box cover (2) are both provided with a heat insulation layer (11), and the heat insulation layer is made of insulation cross-linked closed-cell polyethylene foam plastics.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921190469.0U CN210470814U (en) | 2019-07-26 | 2019-07-26 | Program cooling box for storing freezing bag |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201921190469.0U CN210470814U (en) | 2019-07-26 | 2019-07-26 | Program cooling box for storing freezing bag |
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| Publication Number | Publication Date |
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| CN210470814U true CN210470814U (en) | 2020-05-08 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201921190469.0U Active CN210470814U (en) | 2019-07-26 | 2019-07-26 | Program cooling box for storing freezing bag |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111607561A (en) * | 2020-05-14 | 2020-09-01 | 北京唐颐惠康生物医学技术有限公司 | Method for constructing large-scale, high-throughput and high-safety stem cell bank |
| CN115226705A (en) * | 2022-06-20 | 2022-10-25 | 浙江师范大学 | Cell cryopreservation and resuscitation integrated equipment |
-
2019
- 2019-07-26 CN CN201921190469.0U patent/CN210470814U/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111607561A (en) * | 2020-05-14 | 2020-09-01 | 北京唐颐惠康生物医学技术有限公司 | Method for constructing large-scale, high-throughput and high-safety stem cell bank |
| CN111607561B (en) * | 2020-05-14 | 2023-08-11 | 北京唐颐惠康生物医学技术有限公司 | Construction method of large-scale, high-flux and high-safety stem cell library |
| CN115226705A (en) * | 2022-06-20 | 2022-10-25 | 浙江师范大学 | Cell cryopreservation and resuscitation integrated equipment |
| CN115226705B (en) * | 2022-06-20 | 2024-04-19 | 浙江师范大学 | Cell cryopreservation and resuscitation integrated equipment |
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