CN210394224U - System for separating and purifying amino acid by utilizing continuous ion exchange of simulated moving bed - Google Patents
System for separating and purifying amino acid by utilizing continuous ion exchange of simulated moving bed Download PDFInfo
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- CN210394224U CN210394224U CN201921159078.2U CN201921159078U CN210394224U CN 210394224 U CN210394224 U CN 210394224U CN 201921159078 U CN201921159078 U CN 201921159078U CN 210394224 U CN210394224 U CN 210394224U
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Abstract
The utility model relates to a technical field of device is used in biological product processing especially relates to a system for utilize continuous ion exchange separation purification amino acid of simulated moving bed. The device is composed of a plurality of groups of ion exchange resin column groups which are connected in series and comprises an adsorption column group, a washing column group, a backwashing column group, an elution column group and a regeneration column group. The utility model discloses an utilize system of continuous ion exchange separation purification amino acid of simulated moving bed, utilize the automation and the serialization of valve array formula simulated moving bed system, carry out the separation and purification to amino acid, improved production efficiency, and the purity of the amino acid product that obtains is high.
Description
Technical Field
The utility model relates to a technical field of device is used in biological product processing especially relates to a system for utilize continuous ion exchange separation purification amino acid of simulated moving bed.
Background
Amino acids are essential substances constituting proteins required for animal nutrition, and they are metabolized in the human body to function as ① synthetic tissue proteins, ② converted into ammonia-containing substances such as acids, hormones, antibodies, creatine, etc., ③ converted into carbohydrates and fats, and ④ oxidized into carbon dioxide, water and urea to generate energy.
The yield of amino acid in China reaches 460 ten thousand tons in 2016, and the total yield of amino acid is increased by 24% compared with that in 2015 along with the expansion of the product statistical range and the increase of the yield. At present, the total national amino acid energy counted exceeds 500 million tons, and the new peak of history is reached. The extraction process for producing amino acid by fermentation mostly adopts an ion exchange method, but mainly adopts the traditional single-column ion exchange method, has the problems of low yield, incapability of continuous production, high consumption of chemicals such as water, acid, alkali, eluent and the like, improves the yield and purity of amino acid in fermentation liquor, reduces the production cost and sewage discharge, and is the main pressure of various production enterprises.
At present, a system for separating and purifying amino acid by using simulated moving bed continuous ion exchange is urgently needed.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide an utilize continuous ion exchange separation purification amino acid's of simulated moving bed system, utilize the automation and the serialization of valve array formula simulated moving bed system, carry out the separation and purification to amino acid, improved production efficiency, and the purity of the amino acid product that obtains is high.
The technical scheme of the utility model is that:
a system for separating and purifying amino acid by utilizing continuous ion exchange of a simulated moving bed is composed of a plurality of groups of ion exchange resin column groups which are connected in series and comprises an adsorption column group, a washing column group, a backwashing column group, an elution column group and a regeneration column group.
The upper end of the first resin column of the adsorption column group is provided with a feeding liquid inlet, all the resin columns of the adsorption column group are connected in series end to end, and the lower end of the last resin column of the adsorption column group is provided with a residual liquid outlet.
The upper end of the first resin column of the washing column group is provided with a deionized water inlet, all the resin columns of the washing column group are connected in series end to end, the lower end of the last resin column of the washing column group is provided with a washing liquid outlet, and the washing liquid outlet is connected with a feeding liquid inlet at the upper end of the first resin column of the adsorption column group. The washing liquid outlet is connected with a feeding liquid inlet at the upper end of a first resin column of the adsorption column group; the method can perform secondary adsorption on the amino acid contained in the washing liquid so as to improve the recovery rate of the amino acid, reduce the waste of raw materials and reduce the production cost.
The lower end of the first resin column of the backwashing column group is provided with a deionized water inlet, all the resin columns of the backwashing column group are connected in series end to end, and the upper end of the last resin column of the backwashing column group is provided with a backwashing liquid outlet.
The upper end of the first resin column of the elution column group is provided with an eluent inlet, all the resin columns of the elution column group are connected in series end to end, the lower end of the last resin column of the elution column group is provided with an eluent outlet, and the eluent outlet is connected with an evaporator. Acidifying the concentrated solution with hydrochloric acid, decoloring, crystallizing, filtering, drying and packaging to finally obtain an amino acid hydrochloride product, wherein the water after concentration treatment is used in the steps of washing and backwashing, so that the water is saved and the production cost is reduced.
The upper end of the first resin column of the regeneration column group is provided with a regenerant inlet, all the resin columns of the regeneration column group are connected in series end to end, and the lower end of the last resin column of the regeneration column group is provided with a waste liquid outlet.
The system for separating and purifying amino acid by utilizing the continuous ion exchange of the simulated moving bed adopts a valve array system, and the material inlet and the material outlet of each column group are periodically switched. The periodic switching means that after the resin columns at the first positions of the column groups are completely treated, the combined valves are switched, so that the resin columns at the first positions of the column groups become the final resin columns in the next area, the next process is executed, the amino acid is separated and purified by utilizing the automation and the continuity of a valve array type simulated moving bed system, the production efficiency is improved, and the purity of the obtained amino acid product is high.
The number of resin columns in each column group is 4-12.
Preferably, a leaching column group is further included between the elution column group and the regeneration column group area, a deionized water inlet is arranged at the upper end of the first resin column of the leaching column group, the resin columns of the leaching column group are connected in series end to end, and a leaching solution outlet is arranged at the lower end of the last resin column of the leaching column group. So as to remove the redundant eluant in the resin column, thereby reducing the use amount of the subsequent regenerant, improving the regeneration effect of the resin column and improving the production efficiency; the eluent flows into the intermediate tank and is used as water for preparing the eluent, so that the production cost is reduced, and the discharge of acid-base waste liquid is reduced.
Preferably, the number of the resin columns of the leaching column group is 4-12.
The utility model has the advantages that,
in a washing column group of the simulation moving bed system, a washing liquid outlet is connected with a feeding liquid inlet at the upper end of a first resin column of the adsorption column group; the method can perform secondary adsorption on the amino acid contained in the washing liquid so as to improve the recovery rate of the amino acid, reduce the waste of raw materials and reduce the production cost.
Acidifying the concentrated solution with hydrochloric acid, decoloring, crystallizing, filtering, drying and packaging to finally obtain an amino acid hydrochloride product, wherein the water after concentration treatment is used in the steps of washing and backwashing, so that the water is saved and the production cost is reduced.
In addition, the leaching column group is additionally arranged in the simulated moving bed system to remove redundant eluent in the resin column, so that the use amount of a subsequent regenerant can be reduced, the regeneration effect of the resin column can be improved, and the production efficiency can be improved; the eluent flows into the intermediate tank and is used as water for preparing the eluent, so that the production cost is reduced, and the discharge of acid-base waste liquid is reduced.
In a word, the utility model discloses an utilize system of continuous ion exchange separation purification amino acid of simulated moving bed utilizes the automation and the serialization of valve array formula simulated moving bed system, separates the purification to the amino acid, has improved production efficiency, and the purity of the amino acid product that obtains is high.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic structural view of embodiment 1 of the present invention;
the device comprises a 1-adsorption column group, a 11-feeding liquid inlet, a 12-raffinate outlet, a 2-washing column group, a 21-deionized water inlet, a 22-washing liquid outlet, a 3-backwashing column group, a 31-deionized water inlet, a 32-backwashing liquid outlet, a 4-regeneration column group, a 41-regenerant inlet, a 42-waste liquid outlet, a 5-elution column group, a 51-eluent inlet, a 52-eluent outlet and a 6-evaporator.
Detailed Description
In order to make the technical solutions in the present invention better understood, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, but not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts shall belong to the protection scope of the present invention.
Example 1
A system for separating and purifying amino acid by utilizing continuous ion exchange of a simulated moving bed is composed of a plurality of groups of ion exchange resin column groups which are connected in series and comprises an adsorption column group 1, a washing column group 2, a backwashing column group 3, an elution column group 5 and a regeneration column group 4.
The upper end of the first resin column of the adsorption column group 1 is provided with a feeding liquid inlet 11, all the resin columns of the adsorption column group are connected in series end to end, and the lower end of the last resin column of the adsorption column group is provided with a residual liquid outlet 12.
The upper end of the first resin column of the washing column group 2 is provided with a deionized water inlet 21, all the resin columns of the washing column group are connected in series end to end, the lower end of the last resin column of the washing column group is provided with a washing liquid outlet 22, and the washing liquid outlet is connected with a feeding liquid inlet 11 at the upper end of the first resin column of the adsorption column group. The washing liquid outlet is connected with a feeding liquid inlet at the upper end of a first resin column of the adsorption column group; the method can perform secondary adsorption on the amino acid contained in the washing liquid so as to improve the recovery rate of the amino acid, reduce the waste of raw materials and reduce the production cost.
The lower end of the first resin column of the backwashing column group 3 is provided with a deionized water inlet 31, all the resin columns of the backwashing column group are connected in series end to end, and the upper end of the last resin column of the backwashing column group is provided with a backwashing liquid outlet 32.
An eluent inlet 51 is arranged at the upper end of the first resin column of the elution column group 5, all the resin columns of the elution column group are connected in series end to end, an eluent outlet 52 is arranged at the lower end of the last resin column of the elution column group, and the eluent outlet is connected with the evaporator 6. Acidifying the concentrated solution with hydrochloric acid, decoloring, crystallizing, filtering, drying and packaging to finally obtain an amino acid hydrochloride product, wherein the water after concentration treatment is used in the steps of washing and backwashing, so that the water is saved and the production cost is reduced.
The upper end of the first resin column of the regeneration column group 4 is provided with a regenerant inlet 41, all the resin columns of the regeneration column group are connected in series end to end, and the lower end of the last resin column of the regeneration column group is provided with a waste liquid outlet 42.
The system for separating and purifying amino acid by utilizing the continuous ion exchange of the simulated moving bed adopts a valve array system, and the material inlet and the material outlet of each column group are periodically switched. The periodic switching means that after the resin columns at the first positions of the column groups are completely treated, the combined valves are switched, so that the resin columns at the first positions of the column groups become the final resin columns in the next area, the next process is executed, the amino acid is separated and purified by utilizing the automation and the continuity of a valve array type simulated moving bed system, the production efficiency is improved, and the purity of the obtained amino acid product is high.
The number of resin columns in each column group is 4-12.
Example 2
On the basis of the embodiment 1, a leaching column group is further included between the elution column group and the regeneration column group area, a deionized water inlet is arranged at the upper end of the first resin column of the leaching column group, the resin columns of the leaching column group are connected in series end to end, and a leaching solution outlet is arranged at the lower end of the last resin column of the leaching column group. So as to remove the redundant eluant in the resin column, thereby reducing the use amount of the subsequent regenerant, improving the regeneration effect of the resin column and improving the production efficiency; the eluent flows into the intermediate tank and is used as water for preparing the eluent, so that the production cost is reduced, and the discharge of acid-base waste liquid is reduced.
Preferably, the number of the resin columns of the leaching column group is 4-12.
Although the present invention has been described in detail by referring to the drawings in conjunction with the preferred embodiments, the present invention is not limited thereto. Various equivalent modifications or substitutions can be made on the embodiments of the present invention by those skilled in the art without departing from the spirit and substance of the present invention, and these modifications or substitutions are intended to be within the scope of the present invention/any person skilled in the art can easily conceive of changes or substitutions within the technical scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (8)
1. A system for separating and purifying amino acid by utilizing continuous ion exchange of a simulated moving bed is characterized by being formed by connecting a plurality of groups of ion exchange resin column groups in series and comprising an adsorption column group, a washing column group, a backwashing column group, an elution column group and a regeneration column group; the upper end of a head resin column of the adsorption column group is provided with a feed liquid inlet, all the resin columns of the adsorption column group are connected in series end to end, and the lower end of a tail resin column of the adsorption column group is provided with a residual liquid outlet; the upper end of the first resin column of the washing column group is provided with a deionized water inlet, all the resin columns of the washing column group are connected in series end to end, the lower end of the last resin column of the washing column group is provided with a washing liquid outlet, and the washing liquid outlet is connected with a feeding liquid inlet at the upper end of the first resin column of the adsorption column group.
2. The system for separating and purifying amino acid by using continuous ion exchange of a simulated moving bed according to claim 1, wherein a deionized water inlet is arranged at the lower end of a first resin column of the backwashing column group, the resin columns of the backwashing column group are connected in series end to end, and a backwashing liquid outlet is arranged at the upper end of a last resin column of the backwashing column group.
3. The system for separating and purifying amino acid by using simulated moving bed continuous ion exchange according to claim 1, wherein the upper end of the first resin column of the elution column group is provided with an eluent inlet, the resin columns of the elution column group are connected in series end to end, the lower end of the last resin column of the elution column group is provided with an eluent outlet, and the eluent outlet is connected with an evaporator.
4. The system for separating and purifying amino acid by using simulated moving bed continuous ion exchange according to claim 1, wherein the upper end of the first resin column of the regeneration column group is provided with a regenerant inlet, the resin columns of the regeneration column group are connected in series end to end, and the lower end of the last resin column of the regeneration column group is provided with a waste liquid outlet.
5. The system for separating and purifying amino acid by using simulated moving bed continuous ion exchange according to claim 1, wherein the system for separating and purifying amino acid by using simulated moving bed continuous ion exchange adopts a valve array system, and the material inlet and outlet of each column group are periodically switched.
6. The system for separating and purifying amino acid by using simulated moving bed continuous ion exchange according to claim 1, wherein the number of the resin columns of each column group is 4-12.
7. The system for separating and purifying amino acid by using continuous ion exchange of a simulated moving bed according to claim 1, further comprising a leaching column group between the elution column group and the regeneration column group, wherein the upper end of the first resin column of the leaching column group is provided with a deionized water inlet, the resin columns of the leaching column group are connected in series end to end, and the lower end of the last resin column of the leaching column group is provided with a leaching solution outlet.
8. The system for separating and purifying amino acid by using simulated moving bed continuous ion exchange according to claim 7, wherein the number of the resin columns of the washing column group is 4-12.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114180758A (en) * | 2021-12-16 | 2022-03-15 | 浙江鑫旺钒业控股有限公司 | Intelligent integrated ion exchange system |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114180758A (en) * | 2021-12-16 | 2022-03-15 | 浙江鑫旺钒业控股有限公司 | Intelligent integrated ion exchange system |
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