CN210317700U

CN210317700U - Peristaltic pump and cell culture device using same

Info

Publication number: CN210317700U
Application number: CN201920597700.1U
Authority: CN
Inventors: 温维佳; 宋祺; 高一博
Original assignee: Shenzhen Shineway Hi Tech Co ltd
Current assignee: Shenzhen Shineway Hi Tech Co ltd
Priority date: 2019-04-28
Filing date: 2019-04-28
Publication date: 2020-04-14
Anticipated expiration: 2029-04-28

Abstract

The utility model relates to a peristaltic pump and a cell culture device applying the peristaltic pump, the peristaltic pump mainly comprises a rotary driving part, a pump body, a circular extrusion piece and a hose; the circular extrusion piece is accommodated in the circular inner cavity and is in transmission connection with the rotary power output end, the circular extrusion piece is provided with an inner ring and an outer ring which can rotate relatively, a gap is formed between the circular extrusion piece and the inner peripheral wall of the circular inner cavity, and the rotary axis of the circular extrusion piece is eccentrically arranged relative to the rotary power output end; the hose is wound in a gap between the circular extrusion piece and the inner peripheral wall of the circular inner cavity, and two ends of the hose are overlapped in a crossed mode and then respectively extend out of the first hose opening and the second hose opening. The utility model discloses a peristaltic pump sets up through the inner circle with the circular extrusion spare and the relative rotation of outer lane to reducible circular extrusion spare when rotating and the hose between the friction that produces, and then can prolong the life of circular extrusion spare and hose.

Description

Peristaltic pump and cell culture device using same

Technical Field

The utility model relates to a peristaltic pump, simultaneously, the utility model discloses still relate to an use cell culture device of this peristaltic pump.

Background

The peristaltic pump is a liquid driving device which drives liquid in a tube to flow in a direction by moving an extrusion hose, and has the advantages of no pollution and good sealing property because the liquid flows in the hose and is not in direct contact with an instrument, thereby being widely applied. However, the peristaltic pump in the prior art has a large volume, and cannot meet the requirements of miniaturized equipment such as a microfluidic chip and the like and the delivery of trace liquid. In addition, the friction of the existing peristaltic pump to the hose is large during working, so that the service lives of the hose and the peristaltic pump are greatly shortened.

SUMMERY OF THE UTILITY MODEL

In view of this, the present invention is directed to a peristaltic pump to reduce friction on a hose, thereby prolonging a service life of the hose.

In order to achieve the above purpose, the technical scheme of the utility model is realized like this:

a peristaltic pump, comprising:

a rotary drive section having a rotary power output end;

the pump body is fixed at one end of the rotary driving part, which is provided with the rotary power output end, a circular inner cavity which is coaxial with the rotary power output end is formed in the pump body, and a first hose port and a second hose port which are arranged side by side at one side of the circular inner cavity and form a communication between the outside and the circular inner cavity, and the opening depths of the first hose port and the second hose port are different;

a circular extrusion member accommodated in the circular inner cavity and in transmission connection with the rotary power output end, the circular extrusion member having an inner ring and an outer ring which are relatively rotatable and forming a gap with an inner peripheral wall of the circular inner cavity, and being configured such that a rotation axis is eccentrically disposed with respect to the rotary power output end;

and the hose is wound in a gap between the circular extrusion piece and the inner peripheral wall of the circular inner cavity, two ends of the hose respectively extend out of the first hose port and the second hose port, and the two ends of the hose are overlapped together in a crossed manner before extending into the first hose port and the second hose port due to different opening depths of the first hose port and the second hose port.

Further, the pump body comprises a pump shell and a pump cover, the circular inner cavity is formed in the pump shell, one side of the pump shell is provided with an opening, and a through hole for connecting the circular extrusion part with the power output end is formed in the pump shell on the other side of the circular inner cavity relative to the opening side of the circular inner cavity; the first hose port and the second hose port are formed on the pump shell, and the pump cover forms a sealing cover on one side of the opening of the circular inner cavity.

Furthermore, one side of the first hose port and one side of the second hose port, which are opposite to the pump cover, are opened and are covered by the pump cover.

Further, two ends of the hose extending from the first hose port and the second hose port are respectively set as an inlet end and an outlet end of the hose.

Furthermore, a plurality of groups of fixing holes are correspondingly formed in the pump shell and the pump cover, and the pump body is fixed on the rotary driving part through fixing pieces penetrating through the fixing holes in each group.

Further, the fixing member is a bolt, and the bolt is screwed to the rotation driving portion.

Further, the rotary driving part is a motor, the rotary power output end is a motor shaft of the motor, and the motor shaft is in transmission connection with the circular extrusion piece through a transmission piece; the transmission part comprises a first cylinder fixedly connected with the motor shaft and coaxial, and a second cylinder fixedly connected with the first cylinder and eccentrically arranged with the axis relative to the first cylinder, and the circular extrusion part is connected with the second cylinder.

Further, the transmission part and the motor shaft are integrally formed.

Further, a gasket is fixedly clamped between the pump shell and the rotary driving part, and a through hole which is communicated with the through hole and is used for the transmission part to pass through is formed in the gasket.

Compared with the prior art, the utility model discloses following advantage has:

(1) peristaltic pump, through the inner circle with the circular extrusion spare and the relative rotation setting of outer lane to reducible circular extrusion spare when rotating and the hose between the friction that produces, and then can prolong the life of circular extrusion spare and hose, and can make the liquid in the hose have better output effect.

(2) The pump cover is arranged, so that the circular extrusion part and the hose can be prevented from sliding out of the pump shell in the rotating process.

(3) The first hose mouth and the second hose mouth are just set up to the uncovered setting in one side of pump cover, can be convenient for the installation setting of hose in the pump case.

(4) By overlapping the second hose mouth end on the inlet end of the hose, when the liquid in the hose flows through the overlapping part, the inlet end of the hose can be flattened due to the expansion of the second hose mouth end to prevent the liquid from flowing into the hose from the inlet end of the hose, so that the unidirectional output of the liquid can be realized.

(5) The arrangement of the fixing hole can facilitate the installation of the pump body on the rotary driving part.

(6) A spacer is interposed between the pump case and the rotary drive portion, so that the coupling effect between the pump case and the rotary drive portion can be improved.

The utility model also provides a cell culture device, cell culture device is at least including the micro-fluidic chip or the culture dish that have the cell culture cavity, is constructed with the carrier of liquid reserve tank and waste liquid pond, and constitutes respectively the liquid reserve tank with the waste liquid pond with cell culture cavity intercommunication in micro-fluidic chip or the culture dish, as above with the transport fluid peristaltic pump.

Cell culture device through adopting as above peristaltic pump, can realize continuously changing the culture solution automatically to reducible artificial trouble of bringing of regularly changing the culture solution has also reduced the interference because of manual operation causes the cell growth simultaneously.

Drawings

The accompanying drawings, which form a part hereof, are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiments of the invention and together with the description serve to explain the invention without undue limitation. In the drawings:

fig. 1 is a schematic structural diagram of a peristaltic pump according to a first embodiment of the present invention;

fig. 2 is an exploded view of the peristaltic pump according to a first embodiment of the present invention;

fig. 3 is a schematic structural diagram of a pump casing according to a first embodiment of the present invention;

fig. 4 is a view illustrating an installation state of the hose in the pump housing according to the first embodiment of the present invention;

FIG. 5 is a schematic structural diagram of a transmission member according to a first embodiment of the present invention;

FIG. 6 is a schematic structural view of a cell culture apparatus according to a second embodiment of the present invention;

description of reference numerals:

1-pump cover;

2-round extrusion piece, 21-outer ring, 22-inner ring;

3-pump shell, 31-second fixing hole, 32-circular inner cavity, 33-first hose port, 34-second hose port,

35-a through hole; 4-a gasket;

5-transmission piece, 51-second cylinder, 52-first cylinder;

6, a motor;

7-hose, 71-hose inlet end, 72-hose outlet end;

8-microfluidic chip, 9-liquid storage tank and 10-waste liquid tank.

Detailed Description

It should be noted that, in the present invention, the embodiments and features of the embodiments may be combined with each other without conflict.

The present invention will be described in detail below with reference to the accompanying drawings in conjunction with embodiments. Furthermore, it should be noted that the references to "first" and "second" in the present disclosure are for descriptive purposes only and are not to be construed as limiting relative order or as explicitly or implicitly indicating relative importance.

Example one

The embodiment relates to a peristaltic pump which mainly comprises a rotary driving part, a pump body, a circular pressure accumulating part and a hose in an integral structure. Wherein, the rotary driving part has the rotary power output end, and the pump body links firmly in the rotary driving part one end that has the rotary power output end, is formed with the circular inner chamber with the rotary power output coaxial line in the pump body to be provided with the first hose mouth and the second hose mouth that constitute external and circular inner chamber intercommunication side by side in one side of circular inner chamber, and the opening degree of depth of two hose mouths is different.

The circular extrusion piece is accommodated in the circular inner cavity and is in transmission connection with the rotary power output end, the circular extrusion piece is provided with an inner ring and an outer ring which can rotate relatively, a gap is formed between the circular extrusion piece and the inner peripheral wall of the circular inner cavity, and the rotary axis of the circular extrusion piece is eccentrically arranged relative to the rotary power output end. The hoses are wound in the gap between the circular extrusion piece and the inner peripheral wall of the circular inner cavity and respectively extend out of the two hose ports, and the two hose ports are overlapped in a crossed mode before extending into the two hose ports due to the fact that the opening depths of the two hose ports are different.

An exemplary structure of the peristaltic pump of the present embodiment is shown in fig. 1 and 2 based on the above overall structure, wherein the rotary driving part of the present embodiment specifically employs a motor 6, and the rotary power output end is formed by a motor shaft. In addition, as shown in fig. 2, in the present embodiment, in order to facilitate the arrangement of the circular extrusion member 2 and the hose 7, the pump body specifically includes the pump housing 3 and the pump cover 1 detachably connected together, and the circular extrusion member 2 and the hose 7 are constrained in the circular inner cavity 32 through the pump cover 1.

As shown in fig. 2, the pump cover 1 of the present embodiment is configured as a rectangular plate-like structure as a whole, and a plurality of first fixing holes provided to match the attachment holes on the motor 6 are formed on the pump cover 1. In order to improve the overall appearance, the pump housing 3 is also configured to be substantially rectangular, and a plurality of second fixing holes 31 corresponding to the first fixing holes are formed in the pump housing 3, so that the pump body is fixed to the motor 6 by fixing members sequentially passing through the first fixing holes and the second fixing holes 31.

Wherein, the fixed part generally adopts the bolt among the prior art. However, instead of using a screw connection, it is of course also possible to use other connection structures, such as a snap connection, and, in addition to being detachably connected, the pump housing 3 can also be permanently fixed to the drive, as long as the pump cover is openable. In addition, in order to improve the use effect, in this embodiment, a spacer 4 may be further provided between the pump housing 3 and the motor 6, and the spacer 4 may preferably be circular, and a through hole penetrating the through hole 35 described below and through which the transmission member 5 described below passes is formed in the spacer 4. When the gasket 4 is provided, in order to improve the overall aesthetic property, a groove for accommodating the gasket 4 may be provided at one end of the pump housing 3 close to the motor 6. After the bolt is screwed with the motor 6, the gasket 4 is clamped and fixed between the pump shell 3 and the motor 6.

As shown in fig. 2 and 3, the circular inner cavity 32 is formed in the pump housing 3, and is configured at the other end of the pump housing 3 opposite to the groove, and the circular inner cavity 32 is also arranged at the side of the pump housing 3 which is open for arranging the circular extrusion member 2 and the hose 7, and the pump cap 1 is configured to cover the open side of the circular inner cavity 32. The pump housing 3 on the other side of the circular cavity 32 from the open side is also formed with a through hole 35 through which the transmission member 5 passes to be connected to the motor shaft. As shown in fig. 3 and 4 in combination, the first and

second hose ports

33 and 34 of the present embodiment are also formed on the pump housing 3, and both ends of the hose 7 protruding from the first and

second hose ports

33 and 34 are provided as an inlet end and an outlet end of the hose 7, respectively. In addition, in order to facilitate the installation of the hose 7, the first hose port 33 and the second hose port 34 are also open on the side opposite to the pump cover 1, and both are also closed by the pump cover 1.

In this embodiment, the first hose port 33 and the second hose port 34 have different opening depths, and the hose 7 is overlapped before extending into the two hose ports, so that the liquid in the hose 7 can not flow back. Specifically, taking the example that the depth of the first hose port 33 is greater than that of the second hose port 34, and one end of the hose extending into the first hose port 33 is the hose inlet end 71, and one end of the hose extending into the second hose port 34 is the hose outlet end 72, the hose outlet end 72 is close to the pump cover 1 and is overlapped on the hose inlet end 71, and when the liquid flows through the cross overlapping part of the hose 7 and flows out from the hose outlet end 72 of the hose 7, the expanded outlet end of the hose 7 crushes the other end at the cross overlapping part, so that the liquid can be prevented from flowing back at the hose inlet end 71, and the pumping output of the liquid can be realized.

Note that, in addition to the above examples, the two ends of the hose 7 extending into the first hose port 33 and the second hose port 34 are an inlet end and an outlet end thereof, respectively. Of course, the outlet end and the inlet end of the hose 7 can be exchanged, that is, the two ends of the hose 7 extending into the first hose port 33 and the second hose port 34 are the outlet end and the inlet end, respectively, so as to realize the liquid flow in the other direction without backflow.

In addition, when the liquid flows through the intersection of the hose 7, the portion of the inlet end 71 at the intersection of the hose is pressed against the bottom surface of the circular cavity 32. Meanwhile, it should be noted that, in order to improve the use effect, the widths of the first hose port 33 and the second hose port 34 are also matched with the outer diameter of the hose 7, and the matching design is generally that the outer diameter of the hose 7 is slightly larger than the widths of the first hose port 33 and the second hose port 34, so that after the two ends of the hose 7 are placed and the pump cover 1 is covered, the two ends of the hose 7 can be positioned, and the stability of the arrangement of the hose 7 is ensured.

In the drive connection between the circular extrusion 2 and the motor 6, in this embodiment in particular the motor 6 is in drive connection with the circular extrusion 2 via a transmission piece 5. At this time, as shown in fig. 5, the transmission member 5 specifically includes a first cylindrical body 52 fixed to the motor shaft and coaxial therewith, and a second cylindrical body fixed to the first cylindrical body and having an axis eccentric with respect to the first cylindrical body, and the circular extrusion member 2 is coaxially connected to the second cylindrical body 51. Further, as for the transmission member 5 including the first body 52 and the first body 51, it may be a separate structure as in fig. 5, and both ends are connected to the motor 6 and the circular extrusion 2, respectively, or alternatively, the transmission member 5 may be integrally formed with the motor shaft as a part of the motor shaft as a whole.

In this embodiment, as a preferred embodiment, the circular extrusion 2 having the outer ring and the inner ring can be a bearing structure, and it is only required to use a rolling bearing in the prior art, in which case the inner ring 22 is formed by an inner ring of the rolling bearing, and the outer ring 21 is formed by an outer ring of the rolling bearing. The first cylinder 52 of the transmission member 5 is inserted into the inner ring 22 by interference. Of course, instead of using rolling bearings, the circular extrusion 2 may also take the form of other bearings or bearing-like structures consisting of inner and outer ring structures that are rotatable relative to each other.

Based on above overall description, the peristaltic pump of this embodiment is when using, rotate through motor 6 drive driving medium 5, and drive inner circle 22 by driving medium 5 and rotate for circular inner chamber 32 off-centre, thereby can make outer lane 21 radially extrude hose 7, and realize the peristaltic output of liquid in hose 7, and can rotate for inner circle 22 because of outer lane 21, thereby can reduce the friction to between hose 7 and the outer lane 21, the life of extension hose 7 and circular extruded article 2, it also can improve the rotation effect of circular extruded article 2 simultaneously, and then improve the transport effect of liquid.

Example two

The present embodiment relates to a cell culture apparatus, as shown in fig. 6, the cell culture apparatus includes a microfluidic chip 8 having a cell culture cavity, a carrier configured with a liquid reservoir 9 and a waste liquid reservoir 10, and a peristaltic pump as described in the first embodiment, which is configured to communicate the liquid reservoir 9 and the waste liquid reservoir 10 with the cell culture cavity in the microfluidic chip 8, respectively, to deliver liquid. In addition to the microfluidic chip 8, the cell culture apparatus of this embodiment may also be a culture dish.

The cell culture device of the embodiment can automatically and continuously replace the culture solution in the cell culture cavity by adopting the peristaltic pump, thereby reducing the trouble caused by replacing the culture solution manually and regularly and reducing the interference on cell growth caused by manual operation.

The above description is only a preferred embodiment of the present invention, and should not be taken as limiting the invention, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A peristaltic pump, characterized by: the method comprises the following steps:

a rotary drive section having a rotary power output end;

a pump body fixed at one end of the rotary driving part having the rotary power output end, wherein a circular inner cavity (32) coaxial with the rotary power output end is formed in the pump body, and a first hose port (33) and a second hose port (34) which are arranged side by side at one side of the circular inner cavity (32) and form an external communication with the circular inner cavity (32), and the opening depths of the first hose port (33) and the second hose port (34) are different;

a circular extrusion member (2) accommodated in the circular inner cavity (32) and in transmission connection with the rotary power output end, wherein the circular extrusion member (2) is provided with an inner ring (22) and an outer ring (21) which can rotate relatively, a gap is formed between the circular extrusion member and the inner peripheral wall of the circular inner cavity (32), and the circular extrusion member (2) is configured that the rotation axis is eccentrically arranged relative to the rotary power output end;

and the hose (7) is wound in a gap between the circular extrusion piece (2) and the inner peripheral wall of the circular inner cavity (32), two ends of the hose (7) respectively extend out of the first hose opening (33) and the second hose opening (34), and the two ends are crossed and overlapped together before extending into the first hose opening (33) and the second hose opening (34) due to different opening depths of the first hose opening (33) and the second hose opening (34).

2. A peristaltic pump as set forth in claim 1, wherein: the pump body comprises a pump shell (3) and a pump cover (1), the circular inner cavity (32) is formed in the pump shell (3), is arranged at one side of the pump shell (3) in an opening mode, and is opposite to the opening side of the circular inner cavity (32), and a through hole (35) for connecting the circular extrusion part (2) with the power output end is formed in the pump shell (3) at the other side of the circular inner cavity (32); the first hose port (33) and the second hose port (34) are formed in the pump shell (3), and the pump cover (1) forms a sealing cover on the side of the opening of the circular inner cavity (32).

3. A peristaltic pump as set forth in claim 2, wherein: one sides of the first hose port (33) and the second hose port (34) opposite to the pump cover (1) are arranged in an open mode and are covered by the pump cover (1).

4. A peristaltic pump as set forth in claim 2, wherein: the two ends of the hose (7) protruding from the first hose port (33) and the second hose port (34) are provided as an inlet end and an outlet end of the hose (7), respectively.

5. A peristaltic pump as set forth in claim 2, wherein: a plurality of groups of fixing holes are correspondingly arranged on the pump shell (3) and the pump cover (1), and the pump body is fixed on the rotary driving part by fixing pieces penetrating through the fixing holes of each group.

6. A peristaltic pump as claimed in claim 5, wherein: the fixing piece is a bolt, and the bolt is in bolted connection with the rotary driving part.

7. A peristaltic pump as claimed in any one of claims 2 to 6, wherein: the rotary driving part is a motor (6), the rotary power output end is a motor shaft of the motor (6), and the shaft of the motor (6) is in transmission connection with the circular extrusion part (2) through a transmission part (5); the transmission part (5) comprises a first cylinder (52) which is fixedly connected with a shaft of the motor (6) and coaxial with the shaft of the motor, and a second cylinder (51) which is fixedly connected with the first cylinder (52) and is eccentrically arranged relative to the first cylinder (52), wherein the circular extrusion part (2) is connected with the second cylinder (51).

8. A peristaltic pump as claimed in claim 7, wherein: the transmission piece (5) and the motor (6) are integrally formed.

9. A peristaltic pump as claimed in claim 7, wherein: a gasket (4) is fixedly clamped between the pump shell (3) and the rotary driving part, and a through hole which is communicated with the through hole (35) and is used for the transmission piece (5) to pass through is formed in the gasket (4).

10. A cell culture apparatus, characterized by: the cell culture apparatus comprises at least a microfluidic chip (8) or a culture dish with a cell culture cavity, a carrier configured with a reservoir (9) and a waste reservoir (10), and a peristaltic pump according to any one of claims 1 to 9 constituting the reservoir (9) and the waste reservoir (10) in communication with the cell culture cavity in the microfluidic chip (8) or the culture dish, respectively, for delivering a liquid.