CN210269565U - Device for rapidly measuring compressibility of material - Google Patents

Device for rapidly measuring compressibility of material Download PDF

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Publication number
CN210269565U
CN210269565U CN201920882845.6U CN201920882845U CN210269565U CN 210269565 U CN210269565 U CN 210269565U CN 201920882845 U CN201920882845 U CN 201920882845U CN 210269565 U CN210269565 U CN 210269565U
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China
Prior art keywords
weighing
compressibility
pressing column
weight pressure
weighing device
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CN201920882845.6U
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Chinese (zh)
Inventor
陈永奇
胡芳
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Zhuhai rispril Pharmaceutical Technology Co., Ltd
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Zhuhai Reispril Biopharmaceutical Co ltd
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Abstract

The utility model discloses a device for rapidly measuring material compressibility, which comprises a shell, a material hopper, a weighing device, a compacting device, a weight pressure platform, a material thickness detection device and a guide rail, wherein the weighing device, the weight pressure platform, the compacting device, a material thickness detector and the guide rail are positioned in the shell, the weighing device is positioned below the material hopper, the material hopper is provided with a material stop valve which is electrically connected with the weighing device, the top of the weighing device is provided with a weighing disc, the opening of the weighing disc is just under the material hopper, the compacting device is arranged at a position close to the weighing device, the weight pressure platform is arranged on the guide rail which is positioned at the bottom of the device, the top of the weight pressure platform is provided with a breaker, the material thickness detector is arranged at a position between the weight pressure platform and the compacting device, the material stop valve is electrically connected with the weighing device, the material thickness detector is electrically connected with the breaker.

Description

Device for rapidly measuring compressibility of material
Technical Field
The utility model relates to a measure the device of compressibility, in particular to measure the device of material compressibility, especially a device of rapid survey material compressibility.
Background
The tablet is a tablet-shaped solid preparation formed by uniformly mixing the medicine and the auxiliary materials and then pressing the mixture. The tablet has the following components: the dissolution rate and the bioavailability are better; the dosage is accurate, and the content difference of the medicine in the tablet is small; the quality is stable, the tablet is a dry solid, certain medicines which are easy to oxidize and deteriorate and easy to deliquesce can be protected by coating, and the influence of light, air, moisture and the like on the medicines is small; convenient taking, carrying, transportation and the like, mechanical production, large yield, low cost, easy achievement of sanitary standard and the like, and is one of the most widely applied dosage forms.
The pharmaceutical tablet is prepared from different adjuvants such as carboxymethyl starch sodium, low-substituted hydroxypropyl cellulose, crospovidone, croscarmellose sodium and the like, and common fillers such as starch, microcrystalline cellulose and various sugar alcohol adjuvants. The medicine tablet has more types of used auxiliary materials and more complex formula development.
At present, the process research and development of tablets are in a more original state, process research and development personnel carry out composition according to experience, auxiliary materials with different functions are matched, the adjustment direction is obtained through tabletting, and then the composition adjustment is carried out according to the experience.
It is well known that compressibility in tablet-type products is an important parameter in their production. The compressibility of the product is inseparable from the compressibility of the raw and auxiliary materials therein, and although the compressibility of the mixture is not equal to the sum of the compressibility of the individual materials, to a certain extent, the compressibility of the individual materials is better, and the compressibility of the total mixture for tabletting is also better.
However, in the prior art, the compressibility of the raw and auxiliary materials needs to be tested by firstly pressing the mixed powder of the raw and auxiliary materials into a sheet shape and then measuring the sheet shape by using a hardness tester. The raw and auxiliary materials are weighed according to the formula amount each time, and are mixed or granulated and then are mixed for tabletting, so that the small trial process is complicated, and the working efficiency is low; and for some expensive raw materials, frequent groping of the formula also increases the development cost. Therefore, the existing research method has the defects of long time consumption, low research and development efficiency, high research and development cost and the like.
Therefore, it is necessary to design a device for efficiently measuring the compressibility of a material to improve the research and development efficiency and reduce the research and development cost.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is to provide a device of rapid survey material compressibility, the device effectively promotes the efficiency of research tablet medicine compressibility.
In order to solve the technical problem, the utility model discloses a technical scheme does:
a device for rapidly measuring compressibility of materials comprises: the weighing device, the weight pressure table, the compaction device, the material thickness detector and the guide rail are located in the shell, the weighing device is located below the material hopper, the material hopper is provided with a material stop valve electrically connected with the weighing device, the top of the weighing device is provided with a weighing disc, an opening of the weighing disc is opposite to the lower portion of the material hopper, the compaction device is installed at a position close to the weighing device, the weight pressure table is arranged on the guide rail located at the bottom of the device, the top of the weight pressure table is provided with a destroyer, the material thickness detector is installed at a position between the weight pressure table and the compaction device, the material stop valve is electrically connected with the weighing device, and the material thickness detector is electrically connected with the destroyer.
Preferably, the weighing plate is movably connected with the top of the weighing device.
Preferably, the compacting device is provided with a first compacting column, a second compacting column and a sample tray; one end of the first material pressing column is connected with the lower pressing motor, the other end of the first material pressing column is opposite to the opening of the sample disc, one end of the second material pressing column is connected with the upper pushing motor, the sample disc is located on one side, far away from the upper pushing motor, of the second material pressing column, the upper pushing motor plays a role in limiting the sample disc and ejecting materials after the materials are formed, the height of the second material pressing column can be adjusted according to weight, the upper pushing motor plays a role in limiting the sample disc and ejecting the materials after the materials are formed, and the height of the second material pressing column can be adjusted according to the weight.
More preferably, the compacting device is further provided with a sliding table, and one end of the bottom of the sliding table is movably connected with the sample tray, so that the angle of the sliding table can be adjusted.
Preferably, the material sliding table and the second material pressing column are at an angle of 30-50 degrees.
More preferably, the material sliding table and the second material pressing column are 40-50 degrees.
Preferably, the guide rail spans across the destructor and the space below the slip table; the weight pressure table is electrically connected with the material thickness detector and the compaction device, so that after the compaction device finishes a process of compacting the material, the weight pressure table moves to the outlet of the material sliding table of the compaction device along the sliding rail to receive the material, then moves to the position below the material thickness detector to perform thickness detection, and moves to the position below the breaker to perform material compressibility test after detection is finished.
By adopting the technical scheme, the material stop valve is electrically connected with the weighing device, so that the material stop valve can timely throttle the material of the material hopper according to the set weight, and the weight of the tested material is ensured to be consistent with the set weight. In addition, the compaction device is provided with a push-up motor and a sliding material table, and is matched with a material thickness detector electrically connected with the compaction device and a weight pressure table walking on a guide rail, so that the automation from sample preparation to detection is realized when the compressibility of tablet products is researched, and the research and development efficiency is improved.
Drawings
Fig. 1 is a schematic structural diagram of the present invention.
In the figure, 1-a material hopper, 2-a material stop valve, 3-a weighing disc, 4-a weighing device, 5-an upward pushing motor, 6-a material sliding table, 7-a material thickness detector, 8-a downward pressing motor, 9-a breaker, 10-a weight pressure table, 11-a guide rail, 12-a sample disc, 13-a compaction device, 13 a-a first material pressing column and 13 b-a second material pressing column.
Detailed Description
The following describes the present invention with reference to the accompanying drawings. It should be noted that the description of the embodiments is provided to help understanding of the present invention, but the present invention is not limited thereto. In addition, the technical features related to the embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.
As shown in fig. 1, the utility model provides a device for rapidly measuring compressibility of materials: the device comprises a shell, a material hopper 1, a weighing device 4, a compacting device 13, a weight pressure table 10, a material thickness detection 7 and a guide rail 11, wherein the weighing device 4, the compacting device 13 and the material thickness detection 7 are arranged in the shell, the material hopper 1, the weighing device 4, the compacting device 13, the weight pressure table 10, the material thickness detection 7 and the guide rail 11 are arranged in the shell, the weighing device 4 is arranged below the material hopper 1, the material hopper 1 is provided with a material stop valve 2 electrically connected with the weighing device 4, the top of the weighing device 4 is provided with a weighing disc 3, an opening of the weighing disc 3 is opposite to the lower part of the material hopper 1, the compacting device 13 is arranged at a position close to the weighing device 4, the weight pressure table 10 is arranged on the guide rail 11 at the bottom of the device, the top of the weight pressure table 11 is provided with a breaker 9, the material thickness detection 7 is arranged at a position between the weight pressure table 10 and the compacting device 13, the material thickness detector 7 is electrically connected with the breaker 9.
The material hopper 1, the weighing device 4, the compacting device 13, the material thickness detector 7, the weight pressure table 10 and the destroyer 9 are all provided with sensors, and test data of tested materials are transmitted to a computer for automatic recording.
Wherein, the weighing plate 3 is movably connected with the top of the weighing device 4, and the weighing plate 3 can incline to lead the tested material to slide to the sample plate 12.
Further, the compacting device is provided with a first compacting column 13a, a second compacting column 13b and a sample tray 12; one end of the first pressing column 13a is connected with the pressing motor 8, the other end of the first pressing column 13a is just opposite to the opening of the sample tray 12, one end of the second pressing column 13b is connected with the push-up motor 5, the sample tray 12 is positioned on one side, away from the push-up motor 5, of the second pressing column 13b, the push-up motor 5 plays a role in limiting the sample tray 12 and ejecting materials after the materials are formed, and the height of the second pressing column 13b can be adjusted according to weight.
The second material pressing column 13b is provided with an ejector pin, so that the movably connected sample plate 12 can be conveniently ejected by an inclined angle, and the tested material can slide to the material sliding table 6.
Wherein, the compacting device 13 is also provided with a material sliding table 6, one end of the bottom of the material sliding table 6 is movably connected with the sample tray 12, so that the angle of the material sliding table can be adjusted, and the material sliding table and the second material pressing column form 40-50 degrees.
Wherein the guide rail 11 spans across the destructor 9 and the space below the sliding material table 6; the weight pressure table 10 is electrically connected with the material thickness detector 7 and the compacting device 13, so that after the compacting device 13 completes a process of compacting the material, the weight pressure table 10 moves to the outlet of the material sliding table 6 of the compacting device 13 along the sliding rail to receive the material, then the weight pressure table 10 moves to the position below the material thickness detector 7 to perform thickness detection, and then moves to the position below the breaker 9 to perform material compressibility test after the detection is completed.
Further, the utility model discloses a shell is equipped with data control device, including the state display lamp, the state display detection display panel and the power control button of electricity connection each other, this data control device is connected with all sensor electricity.
The following is a functional description of the main components:
a material hopper 1: the material to be tested is poured into the container from the opening;
and (3) a material stop valve 2: setting the closing time/second according to the weight of the weighing device;
and (3) weighing plate: receiving and pouring materials;
and (4) weighing device: setting and providing parameter information to a material stop valve and a tabletting section according to the weight;
push-up motor 5: the effects of limiting the lower die and ejecting the material after forming are achieved, and the height is adjusted according to the weight;
powder sliding table 6: sliding the molding material to the next working section;
material thickness detector 7: actually measuring the thickness of the formed material and providing actually measured parameters for a breakdown point of the next working section;
pressing down the motor 8: the pressing motor provides material forming pressure;
the destructor (9): adjusting the depth of the breakdown point contact according to parameters provided by the working section;
weight pressure table 10: receiving materials and providing a pressure platform;
guide rail 11: and the upper working section is butted by parallel sliding.
The utility model discloses a use method, including following step:
the method comprises the following steps: a test sample is naturally placed into the material hopper 1, the required weight is set, the required tested material slides down to the weighing disc 3, and the material stop valve 2 at the bottom of the material hopper 1 can cut off in time according to the feedback of the weighing device 4;
step two: the weighing plate 3 is inclined, a tested sample slides to the sample plate 12, and the height of the second material pressing column 13b is adjusted by the push-up motor according to the weight of the material, so that the tested material does not overflow the sample plate 12;
step three: setting a fixed pressure, starting a pressing motor 8, slowly pressing a pressing part (a first material pressing column 13a) downwards into a sample disc, slowly compressing a sample until the sample is formed, and returning the force application part to reset;
step four: the sheet sample is pushed out of the sample tray 12 by the push-up motor 5 and slides to the weight pressure table 10 through the material sliding table 6;
step five: the weight pressure table 10 sends the sheet sample to the material thickness detector 7 along the guide rail 11 to detect and record the thickness of the sample;
step six: and starting the destroyer 9, applying pressure to the molded sample by testing the destroyer, and automatically rebounding the testing needle along with the destroyer to record a pressure value when the molded sample is broken and associated. The pressure value is the compressibility index of the material.
The embodiments of the present invention have been described in detail with reference to the accompanying drawings, but the present invention is not limited to the described embodiments. It will be apparent to those skilled in the art that various changes, modifications, substitutions and alterations can be made in the embodiments without departing from the principles and spirit of the invention, and the scope of the invention is to be accorded the full scope of the claims.

Claims (7)

1. The utility model provides a device of rapid survey material compressibility which characterized in that: the weighing device, the weight pressure table, the compaction device, the material thickness detector and the guide rail are located in the shell, the weighing device is located below the material hopper, the material hopper is provided with a material stop valve electrically connected with the weighing device, the top of the weighing device is provided with a weighing disc, an opening of the weighing disc is opposite to the lower portion of the material hopper, the compaction device is installed at a position close to the weighing device, the weight pressure table is arranged on the guide rail located at the bottom of the device, the top of the weight pressure table is provided with a destroyer, the material thickness detector is installed at a position between the weight pressure table and the compaction device, the material stop valve is electrically connected with the weighing device, and the material thickness detector is electrically connected with the destroyer.
2. The apparatus for rapidly measuring compressibility of materials according to claim 1, wherein: the weighing plate is movably connected with the top of the weighing device.
3. The apparatus for rapidly measuring compressibility of materials according to claim 2, wherein: the compaction device is provided with a first pressing column, a second pressing column and a sample tray; one end of the first material pressing column is connected with the lower pressing motor, the other end of the first material pressing column is opposite to the opening of the sample tray, one end of the second material pressing column is connected with the upper pushing motor, and the sample tray is located on one side, far away from the upper pushing motor, of the second material pressing column.
4. The apparatus for rapidly measuring compressibility of materials according to claim 3, wherein: the compaction device is also provided with a material sliding table, and one end of the bottom of the material sliding table is movably connected with the sample disc.
5. The device for rapidly measuring the compressibility of materials according to claim 4, wherein: the material sliding table and the second material pressing column form a 30-50 degree angle.
6. The apparatus for rapidly measuring compressibility of materials according to claim 5, wherein: the material sliding table and the second material pressing column form a 40-50 degree angle.
7. The apparatus for rapidly measuring compressibility of materials according to claim 6, wherein: the guide rail spans the destructor and a space below the sliding table; the weight pressure table is electrically connected with the material thickness detector and the compaction device.
CN201920882845.6U 2019-06-11 2019-06-11 Device for rapidly measuring compressibility of material Active CN210269565U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201920882845.6U CN210269565U (en) 2019-06-11 2019-06-11 Device for rapidly measuring compressibility of material

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201920882845.6U CN210269565U (en) 2019-06-11 2019-06-11 Device for rapidly measuring compressibility of material

Publications (1)

Publication Number Publication Date
CN210269565U true CN210269565U (en) 2020-04-07

Family

ID=70042110

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201920882845.6U Active CN210269565U (en) 2019-06-11 2019-06-11 Device for rapidly measuring compressibility of material

Country Status (1)

Country Link
CN (1) CN210269565U (en)

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GR01 Patent grant
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TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20201209

Address after: 519000 3rd and 4th floors, building 2, international health port, 628 Airport West Road, Sanzao Town, Jinwan District, Zhuhai City, Guangdong Province

Patentee after: Zhuhai rispril Pharmaceutical Technology Co., Ltd

Address before: Room 313-10, 3rd floor, aviation new town planning exhibition hall, Jinwan District, Zhuhai City, Guangdong Province

Patentee before: Zhuhai Reispril Biopharmaceutical Co.,Ltd.