CN210215208U - Protein affinity chromatography column bucket save set - Google Patents

Protein affinity chromatography column bucket save set Download PDF

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Publication number
CN210215208U
CN210215208U CN201920749559.2U CN201920749559U CN210215208U CN 210215208 U CN210215208 U CN 210215208U CN 201920749559 U CN201920749559 U CN 201920749559U CN 210215208 U CN210215208 U CN 210215208U
Authority
CN
China
Prior art keywords
box
affinity chromatography
protein affinity
open slot
chromatography column
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201920749559.2U
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Chinese (zh)
Inventor
Qi Dai
戴琦
Huihui Zhou
周慧慧
Lizhen Xu
徐丽珍
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wuhan Fine Biological Technology Co Ltd
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Wuhan Fine Biological Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuhan Fine Biological Technology Co Ltd filed Critical Wuhan Fine Biological Technology Co Ltd
Priority to CN201920749559.2U priority Critical patent/CN210215208U/en
Application granted granted Critical
Publication of CN210215208U publication Critical patent/CN210215208U/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Abstract

The utility model discloses a protein affinity chromatography post bucket save set belongs to the storage device field, including box and grafting piece, the open slot has been seted up on the top surface of box, box top surface periphery is equipped with the spacing limit that is higher than the open slot position, the spout is seted up on spacing limit, just the grafting piece sets up the surface on the spacing limit of the other end, the gag lever post passes through the inserted block of one end and sets up the spout swing joint on spacing edge, the moving part cup joints the surface at the stopper, install the cooling fan on the box inner wall, the inside bottom surface of box is equipped with the base in proper order and corresponds respectively with the open slot, the surface of base passes through compression spring and is connected with the support, the both ends of base are passed through connecting piece cooperation bolt and are connected fixedly with spacing ring cover. The utility model discloses a set up ring cover, support cooperation locating part and come effective fixed save to the post bucket, and have control by temperature change and shock attenuation effect, improved the save effect.

Description

Protein affinity chromatography column bucket save set
Technical Field
The utility model relates to a storage device field specifically is a protein affinity chromatography column bucket save set.
Background
Affinity chromatography is a chromatography method for separating biomacromolecules, which is established by utilizing the characteristics of specific recognition and reversible combination of biomacromolecules and certain corresponding specific molecules. Affinity chromatography is a highly effective method for separating proteins, and often requires only one step to obtain a protein of higher purity.
At present, the column barrel storage method used in the affinity chromatography process is centralized and placed, and then the column barrel storage method is matched with a centralized air conditioner for cooling and storing, so that the storage effect is poor, the column barrel storage method is easily influenced by external factors, the column barrel storage method is inconvenient to transport at any time, meanwhile, the regulation and control of the temperature need to be noticed at any time, and people need to supervise at any time, and resources are wasted.
SUMMERY OF THE UTILITY MODEL
An object of the utility model is to provide a protein affinity chromatography column bucket save set carries out effective fixed save to the column bucket through setting up ring cover, support cooperation locating part, and has control by temperature change and shock attenuation effect, has improved the save effect.
The utility model provides a following technical scheme: a storage device for a protein affinity chromatography column barrel comprises a box body, a sliding groove, a limiting rod, a moving part and an inserting block, wherein an open groove is formed in the surface of the top of the box body, a limiting edge higher than the open groove is arranged on the periphery of the surface of the top of the box body, the sliding groove is formed in the limiting edge, the inserting block is arranged on the surface of the limiting edge at the other end of the inserting block, a slot is formed in one end of the inserting block, inserting blocks are arranged at two ends of the limiting rod, the limiting rod is movably connected with the sliding groove formed in the limiting edge through the inserting block at one end of the limiting rod, limiting blocks are arranged at two ends of the moving part, and the;
the refrigerator is characterized in that a refrigerating fan is arranged on the inner wall of the box body, a base is sequentially arranged on the bottom surface inside the box body and corresponds to the open grooves respectively, the surface of the base is connected with the support through a pressure spring, and the two ends of the base are fixedly connected with the limit ring sleeve through connecting pieces matched with bolts.
Preferably, the surface of the outer box body of the refrigerating fan is provided with an air outlet, and the refrigerating temperature range of the refrigerating fan is 10-20 degrees.
Preferably, the inner wall of the moving part is provided with a convex end, the two sides of the inserting block are provided with grooves, and the convex end is attached to the grooves when the moving part is sleeved on the surface of the inserting block.
Preferably, the bottom surfaces of the limiting rod and the limiting block are both provided with rubber pads. Can increase the frictional force between with the post bucket, improve the restriction effect.
Preferably, the diameter of the spacing ring sleeve is about 3 cm-5 cm larger than the diameter of the end face of the column barrel.
Preferably, the top of the box body is provided with a cover plate through a hinge, and the bottom of the box body is provided with universal wheels.
The utility model discloses a technological effect and advantage:
1. the utility model discloses a ring cover and open slot carry out the restriction of position to the post bucket, and the bottom is equipped with the damper who comprises compression spring and support simultaneously, and the gag lever post that can cooperate the box top carries out effective fixed with the stopper to the post bucket, has certain shock attenuation effect simultaneously, avoids external factor to lead to the inside influence that receives of post bucket, has improved the security.
2. The refrigeration fan is installed to the box inner wall for the cooling strengthens the save effect to the albumen composition with this, installs the universal wheel simultaneously, is convenient for transport.
Drawings
Fig. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of the top structure of the box body of the present invention;
FIG. 3 is a schematic view of the top structure of the box body when the movable member of the present invention is connected to the limit rod;
fig. 4 is a schematic structural view of the plug block of the present invention;
fig. 5 is a schematic structural view of the movable member of the present invention mounted on the insertion block;
FIG. 6 is a schematic structural view of the base portion of the present invention;
fig. 7 is a schematic view of the structure of the stop collar of the present invention.
Description of reference numerals: the device comprises a box body 1, a cover plate 2, a universal wheel 3, a refrigerating fan 4, an exhaust port 5, an open slot 6, a sliding slot 7, a limiting rod 8, an insert block 81, a movable piece 9, a protruding end 91, a limiting block 10, a rubber pad 101, an insert block 11, a groove 111, a slot 112, a base 12, a pressure spring 13, a support 14, a limiting ring sleeve 15, a connecting piece 16 and a barrel 17.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.
The utility model provides a protein affinity chromatography column barrel storage device as shown in figures 1-7, including box 1, spout 7, gag lever post 8, moving part 9 and grafting piece 11, open slot 6 has been seted up on the top surface of box 1, box 1 top surface periphery is equipped with the spacing limit that is higher than open slot 6 position, spout 7 sets up on spacing limit, and grafting piece 11 sets up the surface at the spacing limit of the other end, the slot 112 has been seted up to the one end of grafting piece 11, the both ends of gag lever post 8 all are equipped with the grafting piece 81, gag lever post 8 is through the grafting piece 81 of one end and the spout 7 swing joint that sets up on spacing limit, the both ends of moving part 9 all are equipped with stopper 10, moving part 9 cup joints the surface at stopper 10;
the inner wall of the box body 1 is provided with a refrigerating fan 4, the bottom surface inside the box body 1 is sequentially provided with a base 12 and corresponds to the open grooves 6 respectively, the surface of the base 12 is connected with a support 14 through a pressure spring 13, and two ends of the base 12 are fixedly connected with a limit ring sleeve 15 through connecting pieces 16 matched with bolts.
Specifically, the exhaust port 5 has been seted up on the outside box 1 surface of refrigeration fan 4, and the refrigeration temperature interval of refrigeration fan 4 is 10 ~ 20, can effectively regulate and control the temperature in the box 1, makes the albumen composition can save the work with the best environment, avoids receiving external environment factor to influence and leads to the save effect to reduce.
Specifically, be equipped with protruding end 91 on the inner wall of moving part 9, the both sides of grafting piece 11 are equipped with recess 111, and moving part 9 cup joints protruding end 91 and the laminating of recess 111 when grafting piece 11 surface, and fixed effect when reinforcing moving part 9 is idle is convenient for manual slip moving part 9 simultaneously and is carried out follow-up spacing work.
Specifically, the bottom surfaces of the limiting rod 8 and the limiting block 10 are provided with rubber pads 101, so that friction force between the limiting rod and the column barrel 17 can be increased, and the limiting effect is improved. And can cooperate with the pressure spring 13 and the support 14 to provide a cushioning effect to the top and bottom of the pillar barrel 17.
Specifically, the diameter of the spacing ring sleeve 15 is about 3 cm-5 cm larger than the diameter of the end face of the column barrel 17, so that the spacing ring sleeve 15 can be effectively limited, meanwhile, workers cannot difficultly insert the column barrel 17 through the spacing ring sleeve 15, and the working steps are simplified.
Specifically, there is apron 2 at the top of box 1 through hinged mounting, and 1 bottoms of box installs universal wheel 3, is convenient for transport the work to the device.
The working principle is that when in use, the cover plate 2 is firstly opened, the column barrel 17 for protein affinity chromatography to be stored is inserted into the box body 1 through the open slot 6 in sequence, the bottom of the column barrel 17 penetrates through the limit ring sleeve 15 and is placed on the surface of the support 14, the support 14 is pressed to deform the pressure spring 13, the top of the column barrel 17 slightly protrudes out of the open slot 6 at the moment, the top of the column barrel 17 is pressed manually to be aligned with the open slot 6, at the moment, the limit rod 8 is drawn inwards along the sliding slot 7 through the insert block 81 until the insert block 81 at the other end of the limit rod 8 is inserted and fixed with the insert slot 112 arranged on one side of the insert block 11, at the moment, the limit rod 8 is positioned above the two open slots 6 and is contacted with the top of the column barrel 17, and the limit and the column; at this time, the other two column barrels 17 are pressed again, the movable member 9 slides out from the insertion block 11 to the surface of the limiting rod 8, and moves until the two limiting blocks 10 are respectively contacted with the tops of the column barrels 17, so that the position fixing of all the column barrels 17 is completed. When needing to take out, reset moving part and gag lever post 8 in proper order, the top of post bucket 17 is popped out open slot 6 again by the effect of compression spring 13 this moment, directly take out can.
When the egg white is preserved for a long time, the refrigerating fan 4 can be started to regulate and control the temperature in the box body 1, and the temperature is kept between 10 and 20 degrees to ensure the effective preservation of the egg white components; during the process, the universal wheels 3 can be matched to transfer the device.
Finally, it should be noted that: although the present invention has been described in detail with reference to the foregoing embodiments, it will be apparent to those skilled in the art that modifications and variations can be made in the embodiments or in part of the technical features of the embodiments without departing from the spirit and the scope of the invention.

Claims (6)

1. The utility model provides a protein affinity chromatography post bucket save set, includes box (1), spout (7), gag lever post (8), moving part (9) and grafting piece (11), its characterized in that: the movable type water tank is characterized in that an open slot (6) is formed in the surface of the top of the tank body (1), a limiting edge higher than the position of the open slot (6) is arranged on the periphery of the surface of the top of the tank body (1), a sliding groove (7) is formed in the limiting edge, an insertion block (11) is arranged on the surface of the limiting edge at the other end, an insertion groove (112) is formed in one end of the insertion block (11), insertion blocks (81) are arranged at two ends of a limiting rod (8), the limiting rod (8) is movably connected with the sliding groove (7) formed in the limiting edge through the insertion block (81) at one end, limiting blocks (10) are arranged at two ends of a movable part (9), and the movable part (9) is sleeved on the surface of the;
install refrigeration fan (4) on box (1) inner wall, the inside bottom surface of box (1) is equipped with base (12) in proper order and corresponds respectively with open slot (6), the surface of base (12) is passed through compression spring (13) and is connected with support (14), the both ends of base (12) are passed through connecting piece (16) cooperation bolt and are connected fixedly with spacing ring cover (15).
2. The protein affinity chromatography column barrel preservation device of claim 1, wherein: an exhaust port (5) is formed in the surface of the outer box body (1) of the refrigerating fan (4), and the refrigerating temperature range of the refrigerating fan (4) is 10-20 degrees.
3. The protein affinity chromatography column barrel preservation device of claim 1, wherein: the inner wall of the moving piece (9) is provided with a protruding end (91), two sides of the inserting block (11) are provided with grooves (111), and the protruding end (91) is attached to the grooves (111) when the moving piece (9) is sleeved on the surface of the inserting block (11).
4. The protein affinity chromatography column barrel preservation device of claim 1, wherein: the bottom surface of gag lever post (8) and stopper (10) all is equipped with rubber pad (101), can increase and post bucket (17) between frictional force, improves the restriction effect.
5. The protein affinity chromatography column barrel preservation device of claim 1, wherein: the diameter of the spacing ring sleeve (15) is about 3 cm-5 cm larger than the diameter of the end surface of the column barrel (17).
6. The protein affinity chromatography column barrel preservation device of claim 1, wherein: the top of the box body (1) is provided with a cover plate (2) through a hinge, and the bottom of the box body (1) is provided with universal wheels (3).
CN201920749559.2U 2019-05-23 2019-05-23 Protein affinity chromatography column bucket save set Expired - Fee Related CN210215208U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201920749559.2U CN210215208U (en) 2019-05-23 2019-05-23 Protein affinity chromatography column bucket save set

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201920749559.2U CN210215208U (en) 2019-05-23 2019-05-23 Protein affinity chromatography column bucket save set

Publications (1)

Publication Number Publication Date
CN210215208U true CN210215208U (en) 2020-03-31

Family

ID=69927244

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201920749559.2U Expired - Fee Related CN210215208U (en) 2019-05-23 2019-05-23 Protein affinity chromatography column bucket save set

Country Status (1)

Country Link
CN (1) CN210215208U (en)

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GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20200331

Termination date: 20210523

CF01 Termination of patent right due to non-payment of annual fee