CN210198922U - Rack replacement mechanism and cell analyzer - Google Patents

Rack replacement mechanism and cell analyzer Download PDF

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Publication number
CN210198922U
CN210198922U CN201921127400.3U CN201921127400U CN210198922U CN 210198922 U CN210198922 U CN 210198922U CN 201921127400 U CN201921127400 U CN 201921127400U CN 210198922 U CN210198922 U CN 210198922U
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China
Prior art keywords
rack
sample
lock pin
tube rack
positioning portion
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CN201921127400.3U
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Changchun Qi
祁昌春
Shujian Ding
丁舒健
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CHANGZHOU BIDAKE BIOLOGICAL SCIENCE & TECHNOLOGY Co Ltd
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CHANGZHOU BIDAKE BIOLOGICAL SCIENCE & TECHNOLOGY Co Ltd
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Abstract

The utility model discloses a framework of tubes changes mechanism and cell analysis appearance. The pipe support replacement mechanism includes: the sample tube rack is provided with a top surface and a bottom surface which are opposite, the sample tube rack is used for placing a sample tube, and the bottom surface of the sample tube rack is provided with a first positioning part; the pipe support base, the pipe support base has relative top surface and bottom surface, second location portion has on the top surface of pipe support base, when the top surface of pipe support base was arranged in to the bottom surface of sample pipe support, first location portion and second location portion mutually supported the location. The tube rack replacing mechanism can conveniently replace the test tube rack, so that the sample tube rack of the flow tube and the sample tube rack of the centrifugal tube can be installed on and detached from the cell analyzer, and the cell analyzer can directly test samples in the flow tube or the centrifugal tube.

Description

Rack replacement mechanism and cell analyzer
Technical Field
The utility model relates to the technical field of medical equipment, especially, relate to a framework of tubes changes mechanism and cell analysis appearance.
Background
The flow cytometer is a device for automatically analyzing and sorting cells or biological particles, can quickly detect, store and display a series of important biophysical and biochemical characteristic parameters of dispersed cells suspended in a liquid, can sort out specified cell subsets according to a preselected parameter range, is widely applied to basic researches of cell biology, immunology, physiology, molecular biology and the like, and is also used for aspects of medical clinical diagnosis, environmental detection and the like.
When a user actually uses a flow cytometer, due to different processing modes of sample configuration, the user may need to analyze and detect a sample on the flow cytometer using a flow tube, or may need to analyze and detect a sample on the flow cytometer using a centrifuge tube. One of the disadvantages of the existing flow cytometer is that the test tube rack mounting base of the flow cytometer can only be matched with the flow tube, and after a user using the centrifuge tube configures a sample, the sample needs to be transferred from the centrifuge tube into the flow tube to be tested on the computer, so that the use is inconvenient.
Disclosure of Invention
In order to overcome the defects of the prior art, one of the purposes of the utility model is to provide a tube rack replacing mechanism, when the tube rack replacing mechanism is installed on a flow cytometer, the test tube rack can be conveniently replaced, and the test tube rack of the flow tube and the test tube rack of the centrifuge tube can be installed on the flow cytometer by replacing, so that the flow cytometer can directly test samples in the flow tube or the centrifuge tube.
The second objective of the present invention is to provide a cell analyzer using the above tube rack replacing mechanism.
The purpose of the utility model is realized by adopting the following technical scheme:
a rack changing mechanism comprising:
the sample tube rack is provided with a top surface and a bottom surface which are opposite, the sample tube rack is used for placing a sample tube, and the bottom surface of the sample tube rack is provided with a first positioning part;
the pipe support base, the pipe support base has relative top surface and bottom surface, second location portion has on the top surface of pipe support base, when the top surface of pipe support base was arranged in to the bottom surface of sample pipe support, first location portion and second location portion mutually supported the location.
In one embodiment, the first positioning portion is a positioning column, and the second positioning portion is a positioning hole.
In one embodiment, the tube rack replacing mechanism further comprises a locking assembly, the locking assembly comprises a lock pin, the lock pin is provided with a front end and a rear end which are opposite to each other, the tube rack base is provided with a containing hole which is communicated with the second positioning portion and is used for the lock pin to movably penetrate through, the first positioning portion is provided with a lock hole, when the bottom surface of the sample tube rack is placed on the top surface of the tube rack base, the front end of the lock pin is contained in the lock hole of the first positioning portion to lock the first positioning portion, and the front end of the lock pin is withdrawn from the lock hole of the first positioning portion to unlock the first positioning portion.
In one embodiment, the locking assembly further comprises a gland and a spring, wherein a protrusion is arranged on the outer peripheral surface of the lock pin adjacent to the front end, the gland is fixed on the outer side surface of the pipe frame base, the part of the lock pin adjacent to the rear end movably penetrates through the gland, the spring is sleeved on the lock pin, and two ends of the spring respectively abut against the protrusion of the lock pin and the gland so as to keep the lock pin in a trend of moving towards the front end.
In one embodiment, the locking assembly further comprises a handle mounted to the rear end of the locking pin and a nut that fits over the locking pin and between the gland and the handle.
In one embodiment, the first positioning portion is a positioning hole, and the second positioning portion is a positioning column.
In one embodiment, the tube rack replacing mechanism further comprises a locking assembly, the locking assembly comprises a lock pin, the lock pin is provided with a front end and a rear end which are opposite to each other, the sample tube rack is provided with a containing hole which is communicated with the first positioning part and is used for the lock pin to movably penetrate through, the second positioning part is provided with a lock hole, when the bottom surface of the sample tube rack is arranged on the top surface of the tube rack base, the front end of the lock pin is contained in the lock hole of the second positioning part so as to lock the sample tube rack, and the front end of the lock pin is withdrawn from the lock hole of the second positioning part so as to unlock the sample tube rack.
In one embodiment, the locking assembly further comprises a gland and a spring, wherein the periphery of the lock pin adjacent to the front end is provided with a protrusion, the gland is fixed on the outer side surface of the sample tube frame, the part of the lock pin adjacent to the rear end movably penetrates through the gland, the spring is sleeved on the lock pin, and two ends of the spring respectively abut against the protrusion of the lock pin and the gland so as to keep the lock pin in a trend of moving towards the front end.
In one embodiment, the sample tube rack is a first tube rack or a second tube rack, and the first tube rack and the second tube rack are respectively used for placing different types of sample tubes, for example, the first tube rack is used for placing flow-type tubes, and the second tube rack is used for placing centrifuge tubes.
A cell analyzer comprises the pipe frame replacing mechanism.
Compared with the prior art, the beneficial effects of the utility model include at least: the utility model discloses a mechanism is changed to pipe support is through the cooperation location of first location portion and second location portion, the sample pipe support can conveniently be installed on the pipe support base or dismantle from the pipe support base, when two sample pipe supports can match STREAMING pipe and centrifuging tube respectively, change the mechanism through above pipe support and can conveniently change different sample pipe supports, make the sample pipe support of STREAMING pipe, the sample pipe support homoenergetic of centrifuging tube can install on the cell analyzer and pull down, the cell analyzer can directly test to the sample in STREAMING pipe or the centrifuging tube, need not shift the sample from the test tube of adaptation to the test tube of adaptation again.
Drawings
Fig. 1 is a schematic structural view of a pipe rack replacing mechanism according to embodiment 1 of the present invention.
Fig. 2 is a left side view of the pipe rack replacing mechanism according to embodiment 1 of the present invention.
Fig. 3 is an exploded schematic view of a pipe rack replacing mechanism according to embodiment 1 of the present invention.
Fig. 4 is a schematic structural diagram of a sample tube rack according to embodiment 1 of the present invention.
Fig. 5 is a schematic structural view of a locking assembly according to embodiment 1 of the present invention.
Fig. 6 is a plan view of the pipe rack replacing mechanism according to embodiment 1 of the present invention.
Fig. 7 is a schematic cross-sectional view along line AA of fig. 6.
Fig. 8 is a schematic structural view of a pipe rack replacing mechanism according to embodiment 2 of the present invention.
Fig. 9 is a schematic structural diagram of a sample tube rack according to embodiment 2 of the present invention.
In the figure: 10. 20, a pipe frame replacing mechanism; 11. 21, a sample pipe frame; 111. a first positioning portion; 112. a lock hole; 12. 22, a pipe frame base; 121. a second positioning portion; 122. a housing hole; 13. 23, a locking assembly; 131. a lock pin; 132. a gland; 133. a spring; 134. a handle; 135. a nut; 136. a protrusion; 14. an adapter plate.
Detailed Description
Example embodiments will now be described more fully with reference to the accompanying drawings. Example embodiments may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of example embodiments to those skilled in the art. The same reference numerals in the drawings denote the same or similar structures, and thus their repetitive description will be omitted.
The words for expressing the position and direction described in the present invention are all the explanations given by taking the drawings as examples, but can be changed according to the needs, and the changes are all included in the protection scope of the present invention.
Example 1
Referring to fig. 1 to 7, the present embodiment provides a rack replacing mechanism 10, and the rack replacing mechanism 10 can be applied to a cell analyzer (not shown), such as a flow cytometer. Rack change mechanism 10 includes a sample rack 11 and a rack base 12, further includes a locking assembly 13, and may also include an adapter plate 14.
Sample tube rack 11 has opposite top and bottom surfaces, sample tube rack 11 is used for placing sample tubes, sample tube rack 11 of this embodiment is a flow tube sample tube rack 11, and the corresponding sample tubes are flow tubes. The bottom surface of the sample tube rack 11 has a first positioning portion 111, the first positioning portion 111 of this embodiment is a positioning column, and the positioning column extends from the bottom surface of the sample tube rack 11 back to the top surface, as shown in fig. 4, two positioning columns are disposed on the bottom surface of the sample tube rack 11 of this embodiment.
The pipe rack base 12 has a top surface and a bottom surface which are opposite to each other, the top surface of the pipe rack base 12 is provided with a second positioning portion 121, the second positioning portion 121 of the present embodiment is a positioning hole, and the top surface of the pipe rack base 12 is provided with two positioning holes which extend from the top surface of the pipe rack base 12 toward the bottom surface.
When the bottom surface of the sample tube rack 11 is placed on the top surface of the tube rack base 12, the first positioning portion 111 and the second positioning portion 121 are mutually matched and positioned, the matching manner of the first positioning portion 111 and the second positioning portion 121 in this embodiment is plug-in type matching or plug-in type matching of the positioning column and the positioning hole, and in other embodiments, the matching manner of the first positioning portion 111 and the second positioning portion 121 may also be detachable buckle type matching positioning, hook type matching positioning, and block type matching positioning. Through the cooperation location of first location portion 111 and second location portion 121, sample pipe support 11 can conveniently be installed on pipe support base 12 or dismantle from pipe support base 12, when two sample pipe supports 11 can match STREAMING pipe and centrifuging tube respectively, change mechanism 10 through above pipe support and can conveniently change different sample pipe supports 11, make the sample pipe support 11 of STREAMING pipe, the sample pipe support 21 homoenergetic of centrifuging tube in embodiment 2 can install on the cell analyzer and pull down, the cell analyzer can directly test the sample in STREAMING pipe or the centrifuging tube, need not shift the sample from the test tube of unadapted to the test tube of adaptation again.
Referring to fig. 5, the locking assembly 13 includes a locking pin 131, and the locking assembly 13 further includes a gland 132 and a spring 133, and may further include a handle 134 and a nut 135.
The lock pin 131 has opposite front and rear ends, the rack base 12 has a receiving hole 122 communicating with the second positioning portion 121, the lock pin 131 movably passes through the receiving hole 122, the first positioning portion 111 has a lock hole 112, and one of the two first positioning portions 111 of the present embodiment has the lock hole 112.
The front end of the lock pin 131 is engaged with the lock hole 112 of the first positioning portion 111 to lock and unlock the first positioning portion 111. Specifically, when the bottom surface of the sample tube holder 11 is placed on the top surface of the holder base 12, the rear end of the lock pin 131 is pushed to move toward the first positioning portion 111, and when the front end of the lock pin 131 is received in the lock hole 112 of the first positioning portion 111, the front end of the lock pin 131 engages with the lock hole 112 of the first positioning portion 111 to block the first positioning portion 111 from moving up and down, so that the first positioning portion 111 is locked, and the sample tube holder 11 is fixed. The rear end of the lock pin 131 is pulled to move back to the first positioning portion 111, and after the front end of the lock pin 131 exits from the lock hole 112 of the first positioning portion 111, the resistance of the first positioning portion 111 moving up and down disappears, the first positioning portion 111 and the sample tube rack 11 are unlocked, and the sample tube rack 11 can be removed from the rack base 12 to replace another sample tube rack 11.
Referring to fig. 5, a protrusion 136 is provided on the outer circumferential surface of the lock pin 131 near the front end, the protrusion 136 of this embodiment is an annular protrusion, the gland 132 is fixed on the outer side surface of the pipe frame base 12, the gland 132 can be fixed on the outer side surface of the pipe frame base 12 by a screw manner, and the portion of the lock pin 131 near the rear end movably penetrates through the gland 132. The spring 133 is sleeved on the lock pin 131, the spring 133 may be a compression spring, and two ends of the spring 133 respectively abut against the protrusion 136 of the lock pin 131 and the gland 132. Since the pressing cover 132 is fixed to the outer side surface of the rack base 12, the lock pin 131 moves through the accommodation hole 122 of the rack base 12, and the lock pin 131 keeps a tendency to move toward the front end by the elastic force of the spring 133. The rear end of the latch 131 may be fitted with a handle 134, and a nut 135 is fitted over the latch 131 between the cover 132 and the handle 134.
When a user wants to replace the adapted sample tube rack 11, the user pulls the handle 134 outward, the handle 134 drives the lock pin 131 to move outward, the front end of the lock pin 131 exits from the lock hole 112 of the first positioning portion 111 of the current sample tube rack 11, the lock of the first positioning portion 111 is released, and a new sample tube rack 11 is replaced. After the new sample tube rack 11 is installed in place, the handle 134 is released, the lock pin 131 automatically rebounds under the action of the spring 133, and the front end of the lock pin 131 is automatically accommodated in the lock hole 112 of the first positioning portion 111, so that the new sample tube rack 11 is locked. Above-mentioned locking Assembly 13 can conveniently lock and unblock sample pipe support 11 to conveniently change sample pipe support 11, easy operation, it is convenient to change, and the cooperation is reliable.
The bottom surface of the rack base 12 is mounted on an adapter plate 14, and the adapter plate 14 may be mounted on a cell analyzer. Referring to fig. 3, two mounting holes are provided in the pipe rack base 12, and the pipe rack base 12 is mounted on the adapter plate 14 by screws.
Example 2
Referring to fig. 8 and 9, in rack replacing mechanism 20 of the present embodiment, the structures of rack mount 22 and lock assembly 23 are the same as those of rack mount 12 and lock assembly 13 of embodiment 1, respectively, except that sample rack 21 of the present embodiment is a sample rack 21 of a centrifuge tube. In other words, the sample tube rack 11 of the flow tube, the sample tube rack 21 of the centrifuge tube and the tube rack base 22 are the same, the tube rack base 12 of the embodiment 1 and the tube rack base 22 of the embodiment can be adapted to the sample tube rack 11 of the flow tube and the sample tube rack 21 of the centrifuge tube at the same time, different sample tube racks 11 and sample tube racks 21 can be conveniently replaced, and the flow cytometer can directly test samples in the flow tube or the centrifuge tube.
Example 3
The rack change mechanism of this embodiment includes a sample rack and a rack mount (not shown), further includes a locking assembly (not shown), and may also include an adapter plate (not shown) to which the rack mount is mounted.
The sample pipe support has relative top surface and bottom surface, and the sample pipe support is used for placing the sample cell, has first locating part on the bottom surface of sample pipe support. The pipe support base has relative top surface and bottom surface, has second location portion on the top surface of pipe support base, and when the top surface of pipe support base was arranged in to the bottom surface of sample pipe support, first location portion and second location portion mutually supported the location.
As an alternative embodiment of embodiment 1, in the tube rack replacing mechanism of this embodiment, the first positioning portion is a positioning hole, the second positioning portion is a positioning column, and the sample tube rack can be conveniently mounted on or dismounted from the tube rack base through the matching positioning of the first positioning portion and the second positioning portion, so as to replace different sample tube racks.
The locking assembly includes a locking pin, further includes a gland and a spring, and may further include a handle and a nut.
The locking assembly of this embodiment is identical in structure to the locking assembly of embodiment 1, except that the locking assembly of this embodiment is mounted on a sample tube rack.
Specifically, the locking assembly of this embodiment includes a lock pin having opposite front and rear ends, the sample tube holder has a receiving hole communicating with the first positioning portion and through which the lock pin movably passes, and the second positioning portion has a lock hole. The front end of the lock pin is matched with the lock hole of the second positioning part, so that the sample pipe frame is locked and unlocked. When the bottom surface of the sample pipe support is arranged on the top surface of the pipe support base, the front end of the lock pin is accommodated in the lock hole of the second positioning portion, the front end of the lock pin is matched with the lock hole of the second positioning portion to prevent the sample pipe support from moving up and down, so that the sample pipe support is locked, the front end of the lock pin is withdrawn from the lock hole of the second positioning portion, the sample pipe support can move up and down, the sample pipe support is unlocked, and the sample pipe support can be taken down from the pipe support base to replace other sample pipe supports.
The gland and spring of this embodiment function in substantially the same manner as the gland 132 and spring 133 of embodiment 1. Specifically, the outer peripheral surface of the lock pin adjacent to the front end is provided with a protrusion, the protrusion can be an annular protrusion, the gland is fixed on the outer side surface of the sample tube frame, the gland can be fixed on the outer side surface of the sample tube frame in a screw connection mode, and the part of the lock pin adjacent to the rear end movably penetrates through the gland. The spring is sleeved on the lock pin and can be a pressure spring, and two ends of the spring are respectively abutted to the bulge of the lock pin and the gland. Because the gland is fixed on the outer side surface of the sample tube frame, the lock pin movably penetrates through the containing hole of the sample tube frame, and the elastic force of the spring enables the lock pin to keep the trend of moving towards the front end. The rear end of the lock pin can be provided with a handle, and the nut is sleeved on the lock pin and is positioned between the gland and the handle.
When a user wants to replace the adaptive sample pipe rack, the handle is pulled outwards, the handle drives the lock pin to move outwards, the front end of the lock pin withdraws from the lock hole of the second positioning part of the pipe rack base, the locking of the sample pipe rack is released, and a new sample pipe rack is replaced. After the new sample tube frame is installed in place, the handle of the locking assembly on the new sample tube frame is loosened, the lock pin automatically rebounds under the action of the spring, and the front end of the lock pin is automatically accommodated in the lock hole of the second positioning part, so that the new sample tube frame is locked. The locking assembly can conveniently lock and unlock the sample tube rack, so that the sample tube rack is convenient to replace, and the locking assembly is simple in operation, convenient to replace and reliable in matching.
Although embodiments of the present invention have been shown and described, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention, and that those skilled in the art can make changes, modifications, substitutions and alterations to the above embodiments without departing from the spirit and scope of the present invention, and all such changes are intended to be within the scope of the following claims.

Claims (10)

1. A rack changing mechanism, comprising:
the sample tube rack is provided with a top surface and a bottom surface which are opposite, the sample tube rack is used for placing a sample tube, and the bottom surface of the sample tube rack is provided with a first positioning part;
the pipe support base, the pipe support base has relative top surface and bottom surface, second location portion has on the top surface of pipe support base, when the top surface of pipe support base was arranged in to the bottom surface of sample pipe support, first location portion and second location portion mutually supported the location.
2. The tube rack replacement mechanism according to claim 1, wherein the first positioning portion is a positioning post, and the second positioning portion is a positioning hole.
3. The tube rack replacing mechanism according to claim 2, further comprising a locking assembly, wherein the locking assembly comprises a lock pin, the lock pin has a front end and a rear end which are opposite to each other, the tube rack base is provided with a containing hole which is communicated with the second positioning portion and is used for the lock pin to movably pass through, the first positioning portion is provided with a lock hole, when the bottom surface of the sample tube rack is placed on the top surface of the tube rack base, the front end of the lock pin is contained in the lock hole of the first positioning portion to lock the first positioning portion, and the front end of the lock pin is withdrawn from the lock hole of the first positioning portion to unlock the first positioning portion.
4. The tube rack replacing mechanism according to claim 3, wherein the locking assembly further comprises a gland and a spring, the outer circumferential surface of the lock pin adjacent to the front end is provided with a protrusion, the gland is fixed on the outer side surface of the tube rack base, the part of the lock pin adjacent to the rear end movably penetrates through the gland, the spring is sleeved on the lock pin, and two ends of the spring respectively abut against the protrusion of the lock pin and the gland so as to keep the lock pin in a trend of moving towards the front end.
5. The tube rack change mechanism of claim 4, wherein the locking assembly further comprises a handle mounted on a rear end of the locking pin and a nut that fits over the locking pin and between the gland and the handle.
6. The tube rack replacement mechanism according to claim 1, wherein the first positioning portion is a positioning hole, and the second positioning portion is a positioning post.
7. The rack changing mechanism according to claim 6, further comprising a locking assembly, wherein the locking assembly comprises a lock pin, the lock pin has a front end and a rear end opposite to each other, the sample rack has a receiving hole communicating with the first positioning portion and allowing the lock pin to movably pass through, the second positioning portion has a lock hole, when the bottom surface of the sample rack is placed on the top surface of the rack base, the front end of the lock pin is received in the lock hole of the second positioning portion to lock the sample rack, and the front end of the lock pin is withdrawn from the lock hole of the second positioning portion to unlock the sample rack.
8. The tube rack changing mechanism according to claim 7, wherein the locking assembly further comprises a gland and a spring, the outer circumferential surface of the latch adjacent to the front end is provided with a protrusion, the gland is fixed on the outer side surface of the sample tube rack, the part of the latch adjacent to the rear end movably penetrates through the gland, the spring is sleeved on the latch, and two ends of the spring respectively abut against the protrusion of the latch and the gland so as to keep the latch in a tendency of moving towards the front end.
9. The rack changing mechanism according to claim 1, wherein the rack of sample tubes is a first rack or a second rack, and the first rack and the second rack are respectively used for placing different types of sample tubes.
10. A cell analyzer, characterized in that it comprises a tube rack changing mechanism according to any one of claims 1 to 9.
CN201921127400.3U 2019-07-17 2019-07-17 Rack replacement mechanism and cell analyzer Active CN210198922U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201921127400.3U CN210198922U (en) 2019-07-17 2019-07-17 Rack replacement mechanism and cell analyzer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201921127400.3U CN210198922U (en) 2019-07-17 2019-07-17 Rack replacement mechanism and cell analyzer

Publications (1)

Publication Number Publication Date
CN210198922U true CN210198922U (en) 2020-03-27

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN201921127400.3U Active CN210198922U (en) 2019-07-17 2019-07-17 Rack replacement mechanism and cell analyzer

Country Status (1)

Country Link
CN (1) CN210198922U (en)

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