CN210145304U - Animal brain stereotaxic in-vivo electric stimulation device - Google Patents
Animal brain stereotaxic in-vivo electric stimulation device Download PDFInfo
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- CN210145304U CN210145304U CN201920543704.1U CN201920543704U CN210145304U CN 210145304 U CN210145304 U CN 210145304U CN 201920543704 U CN201920543704 U CN 201920543704U CN 210145304 U CN210145304 U CN 210145304U
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Abstract
The utility model provides an animal brain stereotactic in-vivo electrical stimulation device, which comprises a nerve positioning shell and at least one stimulation electrode; the nerve positioning shell comprises a left shell and a right shell, the inner ends of the left shell and the right shell are coaxially sleeved, and the outer ends of the left shell and the right shell are respectively provided with a nerve through hole for the nerve to be stimulated to pass through; the left and right shell sleeves are respectively formed by hinging an upper half shell and a lower half shell, and the upper half shell and the lower half shell of each shell sleeve are locked at a closed position by a locking mechanism; the stimulation electrode is arranged on the left shell sleeve or the right shell sleeve, and the electrode contact of the stimulation electrode can be radially adjusted to be positioned in the corresponding shell sleeve. The utility model provides an animal brain stereotaxis is at body electro photoluminescence device can avoid the oppression of internal organs to stimulating the electrode contact, guarantees stimulating electrode contact and the neural comparatively stable contact of target, improves the research effect of electro photoluminescence experiment.
Description
Technical Field
The utility model relates to an animal experiment medical instrument technique, in particular to an animal brain stereotaxic in-vivo electrical stimulation device.
Background
The nervous system functions to coordinate actions and transmit signals in different parts of the body. The receptors sense various stimuli of internal and external environments, transmit the stimuli to the central nervous system through afferent nerves and then transmit information to organs of the whole body through efferent nerves after the stimuli are integrated, so that the activities of the organs are regulated, the coordination of the activities of the organs and the system of the body is ensured, and normal life activities are maintained, therefore, the research on the action of the neural stimuli on the body is of great significance.
Neurological disorders are a large group of neurological diseases with high morbidity, including dyskinesia diseases such as severe Parkinson's disease, epilepsy, intractable pain and the like, and as a result, patients are obviously disabled. The implanted nerve stimulator is one kind of electronic device for helping nerve damage to restore function, and has stimulating electrode contact to contact directly with the nerve stimulating target point and applying certain current pulse to stimulate the nerve target point to regulate or restore the function of brain nerve or muscle and restore the normal operation of biological function.
At present, when an electrical stimulation operation is carried out on an animal by using a brain stereotaxic apparatus, an external electrode rod is usually inserted from the upper part of the head of the animal to carry out the operation on the electrical stimulation time of the brain nerves. When the nerve in the abdominal cavity of the animal is electrically stimulated, the positioned animal body cannot be twisted, the spine is easily injured by twisting, and even the spine is dead, so that the external electrode is not easy to insert, and the stable stimulation to the target spot in the abdominal cavity is not easy to realize. And the incision of the abdominal cavity is usually large, the incision needs to be kept open in the stimulation process of the external electrode, and the long-time open of the abdominal cavity has great harm to the abdominal cavity of the experimental body. The electrode contact of the external electrode is easily pressed by internal organs to deviate from target nerves, and the continuous stimulation monitoring effect is influenced.
SUMMERY OF THE UTILITY MODEL
The utility model provides an animal brain stereotaxis is at body electro photoluminescence device can avoid the oppression of internal organs to stimulating the electrode contact, guarantees stimulating electrode contact and the neural comparatively stable contact of target, improves the research effect of electro photoluminescence experiment.
In order to realize the technical purpose, the technical effect is achieved, and the utility model discloses a following technical scheme solves above-mentioned problem:
the animal brain stereotactic in vivo electric stimulation device comprises a nerve positioning shell and at least one stimulation electrode; the nerve positioning shell comprises a left shell and a right shell, the inner ends of the left shell and the right shell are coaxially sleeved, and the outer ends of the left shell and the right shell are respectively provided with a nerve through hole for the nerve to be stimulated to pass through; the left and right shell sleeves are respectively composed of an upper half shell and a lower half shell which are hinged, the upper half shell and the lower half shell of each shell sleeve are locked at a closed position by a locking mechanism, and a sliding positioning groove and a sliding block which are mutually acted are respectively arranged between the upper half shell and the lower half shell of the left and right shell sleeves at the sleeved position, the sliding positioning groove is of a tooth comb-shaped groove structure and comprises a straight groove for the sliding block to axially slide and a circumferential groove which is arranged at the side part of the straight groove at equal intervals and can be used for the sliding block to slide into for positioning, and when the sliding block slides into the tail end of the circumferential groove for positioning, the closed positions of the upper half shell and the lower; the stimulation electrode is arranged on the left shell sleeve or the right shell sleeve, and the electrode contact of the stimulation electrode can be radially adjusted to be positioned in the corresponding shell sleeve.
In the scheme, the positioning shell is composed of a left shell and a right shell which are coaxially sleeved, and the sleeving part is provided with the slide positioning groove and the slide block which interact with each other, so that the left shell and the right shell relatively slide and are positioned, and the working length of the positioning shell is adjustable. And the left and right casings are composed of hinged upper and lower half shells, the hinge plane divides the nerve through holes at the outer ends of the left and right casings, the upper and lower half shells can be conveniently placed into nerves to be detected when opened, and the positioning casing can be well positioned in the nerves to be detected by closing the upper and lower half shells. The radial distance between the stimulating electrode and the corresponding shell sleeve is adjusted, so that the electrode contact can be ensured to be in better contact with the nerve to be measured.
The diameter of the outer end of each shell is smaller than that of the inner end, so that the outer section of each shell is in a frustum shape. Left and right shell cover adopts the outer end for the frustum structure that reduces gradually, makes the shell cover outside have the buffering slope, the pressure of the internal cortex of reducible experiment.
The elastic rubber pad is arranged on the wall of the neural through hole, so that the compression on nerves can be reduced, and the application range of the neural through hole is widened.
The locking mechanism comprises a buckle and a buckle groove which are respectively arranged on the upper half shell and the lower half shell.
The stimulating electrode comprises an electrode rod, an electrode contact is arranged at the front end of the electrode rod, the rear end of the electrode rod is connected with an external power supply and a control device through a circuit, and the electrode rod is screwed in an electrode mounting screw hole formed in the corresponding shell through a screw rod body in the middle.
The utility model has the advantages and effects that:
1. in the above technical scheme of the utility model, the left and right shell that constitute neural location shell can be in opposite directions or reverse slip, can be according to experimental body nerve length adjustment working length.
2. The utility model discloses well left and right shell cover respectively by upper and lower half casing articulated constitute, open upper and lower half casing can be convenient for wait to detect during the nerve puts into the device.
3. The utility model discloses stimulating electrode and neural location shell threaded connection, threaded connection adjustable length can realize the regulation of electrode contact and neural location shell center axis distance, can make the device better be applicable to different diameters and wait to detect nervous stimulation experiment.
Drawings
FIG. 1 is a schematic structural diagram of an animal brain stereotactic in-vivo electrical stimulation apparatus;
FIG. 2 is a schematic view of the upper and lower housing halves of FIG. 1 shown in an open configuration;
FIG. 3 is a schematic view of the right shell of FIG. 1 shown in an open configuration;
fig. 4 is a schematic diagram of a structure of a stimulation electrode.
And (3) identifying the figure number: 1. the nerve stimulation device comprises stimulation electrodes 1-1, electrode contacts 1-2, electrode rods 1-3, a screw body 2, a left shell, a right shell, 4, nerve through holes 5, a half shell, 5-1, an upper half shell, 5-2, a lower half shell, 6, a sliding positioning groove 6-1, a straight groove 6-2, a circumferential groove 7, a sliding block 8, electrode installation screw holes 9, a buckle 10 and nerves to be stimulated; 11. and (6) buckling grooves.
Detailed Description
The present invention will be further described with reference to the following examples, but the present invention is not limited to these examples.
The animal brain stereotactic in-vivo electrical stimulation device comprises a nerve positioning shell and a stimulation electrode 1, wherein the nerve positioning shell comprises a left shell 2 and a right shell 3, the inner ends of the left shell 2 and the right shell 3 are coaxially sleeved (the inner port of the right shell 3 is sleeved on the inner port of the left shell 2), the outer ends of the left shell 2 and the right shell 3 are provided with coaxial nerve through holes 4 for the nerves 10 to be stimulated to pass through, the inner walls of the nerve through holes 4 are padded with elastic rubber pads, and the diameter of the outer end of each shell is smaller than that of the inner end, so that the outer section of each shell is in a frustum shape, as shown in fig. 1, fig. 2 and fig. 3.
The left and right casings 2 and 3 are both composed of an upper half shell 5 and a lower half shell 5 hinged at the rear side, each nerve through hole 4 is divided into a semicircular hole on the upper half shell 5-1 and a semicircular hole on the lower half shell 5-2, the two half shells 5 of the left casing 2 are locked at the closed position of the front side by a left locking mechanism, the two half shells 5 of the right casing 3 are locked at the closed position of the front side by a right locking mechanism, and each locking mechanism comprises a buckle 9 and a buckle groove 11 which are respectively arranged on the upper half shell 5-1 and the lower half shell 5-2, as shown in fig. 1, fig. 2 and fig. 3.
The upper half shell 5-1 of the left and right shell sleeves 2, 3, the lower half shell 5-2 of the left and right shell sleeves 2, 3 are provided with mutually-acting sliding positioning grooves 6 and sliding blocks 7, each sliding positioning groove 6 is arranged on the half shell 5 of the left shell sleeve 2 and comprises a straight groove 6-1 along the axial direction and a circumferential groove 6-2 which is arranged on the side part of the straight groove 6-1 at equal intervals and communicated with the straight groove, two sliding blocks 7 along the axial direction are arranged on the half shell 5 of the right shell sleeve 2, the distance between the two sliding blocks 7 is equal to the distance between the adjacent circumferential grooves 6-2, the two sliding blocks 7 can rotate into and out of the tail end and the front end of the corresponding adjacent circumferential groove 6-2 along with the relative rotation between the left and right shell sleeves 2, 3, the front end of the adjacent circumferential groove 6-2, namely the straight groove 6-1, the left and right shell sleeves 2, 3 can axially move to adjust the length of the nerve positioning shell sleeves, after the length is adjusted in place, the left and right casings 2 and 3 are rotated to enable the two sliding blocks 7 to enter the tail ends of the adjacent circumferential grooves 6-2 corresponding to the length to be axially limited, the closed ends of the upper half shells 5-1 and the lower half shells 5-2 of the left and right casings 2 and 3 are parallel and level (the hinged ends of the upper half shells 5-1 and the lower half shells 5-2 of the left and right casings 2 and 3 are parallel and level), the upper half shells 5-1 and the lower half shells 5-2 of the left and right casings 2 and 3 can be opened simultaneously by unfastening the buckles 9, the nerve 10 to be stimulated can be placed in a working area, the upper half shells 5-1 and the lower half shells 5-2 are closed, and the buckles 9 are closed, so that the device can be positioned on the nerve 10 to be stimulated, as shown in fig. 1, 2 and 3.
The stimulating electrode 1 comprises an electrode contact 1-1 and an electrode rod 1-2, the electrode rod 1-2 is rotatably installed in an electrode installation screw hole 8 formed in a lower half shell 5-2 of the left shell sleeve 2 through a screw rod body 1-3 in the middle, the electrode contact 1-1 is arranged at the front end of the electrode rod 1-2 in the lower half shell 5-2, the rear end of the electrode rod 1-2 is connected with an external power supply and a control device through a circuit outside the lower half shell 5-2, the radial position of the electrode contact 1-1 can be adjusted through the screwing-in and screwing-out of the screw rod body 1-3, so that the electrode contact 1-1 is reliably contacted with the nerve 10 to be stimulated, the stimulating electrode is suitable for testing the nerve 10 to be stimulated in different diameters, and meanwhile, the contact area of the electrode contact 1-1 and the nerve 10 to be stimulated can be conveniently adjusted, and the acting force applied to the nerve 10 to be, as shown in fig. 1, 2, 3, and 4.
The working principle of the embodiment is as follows:
1. the right shell 3 is rotated to rotate the sliding block 7 at the sleeve connecting end out of the circumferential groove 6-2 into the straight groove 6-1, the sliding block 7 slides along the straight groove 6-1 to adjust the relative distance between the left shell 2 and the right shell 3, the right shell 3 is rotated reversely after the length adjustment is finished to rotate the sliding block 7 from the straight groove 6-1 into the tail end of the corresponding circumferential groove 6-2 for positioning, and the axial sliding of the left shell 2 and the right shell 3 is limited at the moment.
2. After the left buckle 9 and the right buckle 9 are unbuckled, the upper half shells 5-1 of the left shell 2 and the right shell 3 are simultaneously turned upwards, the nerve 10 to be stimulated is placed into the nerve positioning shell, and the nerve 10 to be stimulated is matched with the nerve through hole 4 (semicircular hole) of the lower half shells 5-2 of the left shell 2 and the right shell 3.
3. The screwing electrode rod 1-2 adjusts the distance between the electrode contact 1-1 and the nerve 10 to be stimulated, and ensures that the electrode contact and the nerve 10 have good contact.
4. And simultaneously, the upper half shell 5-1 of the left shell 2 and the upper half shell 5-1 of the right shell 2 are turned down to be closed with the lower half shell 5-2 and the left buckle 9 and the right buckle 9 are locked, so that the nerve 10 to be stimulated is well wrapped by the nerve positioning shell, a good positioning effect can be achieved, and the electrode contact 1-1 can be ensured not to be separated from the nerve 10 to be stimulated in the stimulation process.
The embodiments of the present invention are described in detail with reference to the drawings, but the present invention is not limited to the described embodiments. Various changes, modifications, substitutions and alterations to these embodiments may be made without departing from the principles and spirit of the invention, which is within the scope of the invention.
Claims (5)
1. Animal brain stereotaxic in-vivo electric stimulation device, its characterized in that: comprises a nerve positioning shell and at least one stimulating electrode (1); the nerve positioning shell comprises a left shell (2) and a right shell (3) which are coaxially sleeved at the inner ends, and the outer ends of the left and right shells (2, 3) are respectively provided with a nerve through hole (4) for a nerve (10) to be stimulated to pass through; the left and right casings (2, 3) are composed of hinged upper and lower half shells (5-1, 5-2), the upper and lower half shells (5-1, 5-2) of each casing are locked by a locking mechanism at the closed position, interactive sliding positioning grooves (6) and sliding blocks (7) are respectively arranged between the upper half shells (5-1) and the lower half shells (5-2) of the left and right casings (2, 3) at the sleeved position, the sliding positioning grooves (6) are of a tooth comb-shaped groove structure and comprise straight grooves (6-1) for the sliding blocks (7) to axially slide and circumferential grooves (6-2) which are arranged at equal intervals at the side parts of the straight grooves (6-1) and used for the sliding blocks (7) to slide into and position, when the sliding blocks (7) slide into the circumferential grooves (6-2) to position, the upper part, the lower part and the lower part of the left and right casings (2, 3) are respectively connected, The closed parts of the lower half shells (5-1 and 5-2) are flush; the stimulation electrode (1) is arranged on the left shell sleeve (2) or the right shell sleeve (3), and the electrode contact (1-1) of the stimulation electrode (1) can be radially adjusted to be positioned in the corresponding shell sleeve.
2. The animal brain stereotactic, in vivo electrical stimulation apparatus of claim 1, wherein: the diameter of the outer end of each shell is smaller than that of the inner end, so that the outer section of each shell is in a frustum shape.
3. The animal brain stereotactic, in vivo electrical stimulation apparatus of claim 1, wherein: and an elastic rubber pad is arranged on the wall of the nerve through hole (4).
4. The animal brain stereotactic in vivo electrostimulation device of any of claims 1-3, further comprising: the locking mechanism comprises a buckle (9) and a buckle groove (11) which are respectively arranged on the upper half shell (5-1) and the lower half shell (5-2).
5. The animal brain stereotactic in vivo electrostimulation device of any of claims 1-3, further comprising: the stimulation electrode (1) comprises an electrode rod (1-2), the electrode contact (1-1) is arranged at the front end of the electrode rod (1-2), the rear end of the electrode rod (1-2) is connected with an external power supply and a control device through a circuit, and the electrode rod (1-2) is screwed in an electrode mounting screw hole (8) formed in the corresponding shell through a screw rod body (1-3) in the middle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920543704.1U CN210145304U (en) | 2019-04-19 | 2019-04-19 | Animal brain stereotaxic in-vivo electric stimulation device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920543704.1U CN210145304U (en) | 2019-04-19 | 2019-04-19 | Animal brain stereotaxic in-vivo electric stimulation device |
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| CN210145304U true CN210145304U (en) | 2020-03-17 |
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| CN201920543704.1U Expired - Fee Related CN210145304U (en) | 2019-04-19 | 2019-04-19 | Animal brain stereotaxic in-vivo electric stimulation device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110025886A (en) * | 2019-04-19 | 2019-07-19 | 桂林医学院 | Animal Naoliqing capsule is in body electrical stimulation device |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110025886A (en) * | 2019-04-19 | 2019-07-19 | 桂林医学院 | Animal Naoliqing capsule is in body electrical stimulation device |
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Granted publication date: 20200317 Termination date: 20210419 |
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| CF01 | Termination of patent right due to non-payment of annual fee |