CN210138368U

CN210138368U - Thrombolytic catheter device

Info

Publication number: CN210138368U
Application number: CN201822080855.6U
Authority: CN
Inventors: 袁凯; 王茂强; 王燕; 阎洁羽; 张金龙; 袁冰; 付金鑫; 王修琪
Original assignee: Chinese PLA General Hospital
Current assignee: Chinese PLA General Hospital
Priority date: 2018-12-11
Filing date: 2018-12-11
Publication date: 2020-03-13
Anticipated expiration: 2028-12-11

Abstract

The embodiment of the utility model discloses dissolve bolt pipe device, dissolve bolt pipe device includes interior sleeve pipe, cover and arranges in the outer tube in the interior sleeve pipe outside and fixed outer tube and interior sheathed tube base, the outer tube with there is the chamber of filling between the interior sleeve pipe, the distal end of outer tube is equipped with a plurality of holes of filling, be equipped with on the base with fill the entrance of pouring of hole intercommunication and interior sleeve pipe inlet port, fill the chamber with interior sleeve pipe inner chamber is independent each other, does not link up each other. The utility model discloses a dissolve bolt pipe device sets up a plurality of filling holes at the outer sheathed tube distal end on the one hand, improves and dissolves bolt efficiency to and cover the heparin coating on the outer sheathed tube lateral wall, be close to the hydrophilic coating of base department coating, prevent in the use, form the thrombus around the pipe, improved and dissolved bolt effect and dissolve bolt efficiency.

Description

Thrombolytic catheter device

Technical Field

The utility model relates to the technical field of medical equipment, concretely relates to dissolve bolt pipe device.

Background

At present, the diameter of a thrombus/thrombolysis catheter which is clinically obtained is large, but the diameter cannot reach the artery at the far end of the limb, and the outer layer of the catheter wall does not have an anti-coagulation coating, so that thrombus distributed along the circumference of the catheter is easily formed after long-time retention, and the limb ischemia is further aggravated.

In summary, in the prior art, the thrombolytic catheter has the defects that the distal artery cannot be reached, the thrombolytic effect is poor, and thrombus is easily formed around the catheter, so that further improvement is needed.

SUMMERY OF THE UTILITY MODEL

An object of the embodiment of the utility model is to provide a dissolve bolt pipe device for solve among the prior art dissolve bolt pipe dissolve bolt inefficiency, and form the defect of thrombus around dissolving bolt pipe easily.

In order to achieve the above object, the embodiment of the utility model provides a dissolve bolt pipe device, dissolve bolt pipe device includes interior sleeve pipe, cover and arranges in the outer tube in the interior sleeve pipe outside and fixed outer tube and interior sheathed tube base, the outer tube with be formed with between the interior sleeve pipe and fill the chamber, the distal end of outer tube is equipped with a plurality of filling holes, be equipped with on the base with fill the entrance of irritating of hole intercommunication and interior sleeve pipe inlet port, fill the chamber with interior sleeve pipe inner chamber is independent mutually, does not link up each other.

In one embodiment of the present invention, the outer wall of the distal end of the outer cannula is covered with a heparin coating.

In one embodiment of the present invention, the outer side wall of the outer sleeve is covered with a layer of e-PTFE coating.

In one embodiment of the present invention, the outer side wall of the outer sleeve is close to the base.

In one embodiment of the present invention, the inner sidewall and the outer sidewall of the inner sleeve are both covered with one layer of e-PTFE coating.

In one embodiment of the present invention, the inner sidewall of the inner sleeve is coated with a hydrophilic coating.

In one embodiment of the present invention, the distal and proximal ends of the outer cannula are provided with marker rings.

In one embodiment of the present invention, the number of the filling holes is 6-12, and the interval between adjacent filling holes is 1 cm.

In one embodiment of the present invention, the distal end of the outer cannula is formed with a soft tip having a length of 4-6 cm.

In one embodiment of the present invention, the outer sleeve is close to the outer side wall of the outer sleeve, and the base is provided with a protection tube and a protection cover connected with the protection tube.

The embodiment of the utility model provides a have following advantage:

the utility model discloses a dissolve bolt pipe device sets up a plurality of filling holes at the outer sheathed tube distal end on the one hand, improves and dissolves bolt efficiency to and cover the heparin coating on the outer sheathed tube lateral wall, be close to the hydrophilic coating of base department coating, prevent in the use, form the thrombus around the pipe, improved and dissolved bolt effect and efficiency.

Drawings

Fig. 1 is a schematic structural view of a thrombolytic catheter device according to an embodiment of the present invention.

In the figure: 100-outer sleeve; 110-an infusion orifice; 120-a fill port; 200-inner sleeve; 210-inner cannula access port; 210-; 400-marker loop; 500-coating the outer sleeve with a heparin coating section; 600-outer sleeve coating hydrophilic layer section; 700-soft tip; 800-protecting the tube; 900-protective cover.

Detailed Description

The following description is provided for illustrative purposes, and other advantages and features of the present invention will become apparent to those skilled in the art from the following detailed description.

It should be understood that the structures, ratios, sizes, etc. shown in the present specification are only used to match the contents disclosed in the specification, so as to be known and read by those skilled in the art, and are not used to limit the practical limitations of the present invention, so that they do not have the essential meaning in the art, and any modification of the structures, changes of the ratio relationship, or adjustment of the sizes should still fall within the scope of the present invention without affecting the function and the achievable purpose of the present invention. Meanwhile, the terms such as "upper", "lower", "left", "right", "middle", and the like used in the present specification are for the sake of clarity only, and are not intended to limit the scope of the present invention, and changes or adjustments of the relative relationship thereof are also considered to be the scope of the present invention without substantial changes in the technical content.

In the embodiment of the present invention, the far end and the near end are referred to the base 6 of the thrombolytic device for operation, the near end is close to the base, and the far end is far from the base.

As shown in fig. 1, the thrombolytic catheter device of the embodiment of the present invention comprises an inner sleeve 200, an outer sleeve 100 sleeved outside the inner sleeve 200, and a base 300 for fixing the outer sleeve and the inner sleeve, wherein a perfusion cavity is formed between the inner side walls of the outer sleeve 100 and the inner sleeve 200, a plurality of perfusion holes 110 are arranged at the distal end of the outer sleeve, the number of the perfusion holes 110 is 6-12, and the interval between adjacent perfusion holes 110 is 1 cm. The base 300 is provided with a filling port 120 communicated with the filling hole and an inner sleeve inlet 210, and the inner cavities of the filling cavity and the inner sleeve 200 are independent and not communicated with each other. The infusion port 120 on the base 300 can be connected with a drug pump, drugs are pumped in through the drug pump, and the drugs reach the position of thrombus through the infusion hole after passing through the infusion cavity, so that the purpose of rapid thrombolysis is achieved. The embodiment of the utility model provides a dissolve and tie catheter device can be used to venous system puts the pipe and dissolves the thrombus, takes the dark vein thrombus of lower limb as the example, under the prerequisite that the vena cava filter was put into, carries out garrulous thrombus and suction to the bold thrombus, then, goes into the continuous anti-freezing and/or dissolve the thrombus number of days of medicine through keeping somewhere the catheter device and go into. The anticoagulant coating on the outer side of the outer sleeve wall effectively ensures that the thrombus is not formed in the blood vessel cavity after being left for a long time, the diameter of the thinner outer sleeve can also ensure that the outer sleeve goes deep into the far end of the vein, and the infusion hole is injected under high pressure, so that a better thrombolytic effect is achieved.

The utility model discloses length of outer tube 100 is 100 and supplys 150cm, and the biggest external diameter of outer tube 100 is 4.0Fr, 1.36mm promptly, and the minimum external diameter of outer tube 100 is 2.9Fr, 0.95mm promptly, is the most advanced external diameter of outer tube 100 distal end. The inner sleeve 200 allows the maximum outer diameter through the guide wire to be 0.41mm, the maximum injection pressure of both the inner sleeve 200 and the outer sleeve 100 is 5520kPa, i.e., 800psi, and the tensile strength of the outer sleeve 100 is not less than 5N, i.e., 510 gf. The outer sleeve of the thrombolytic catheter device provided by the embodiment of the utility model has a thin pipe diameter, can be selectively inserted into the blood vessel at the far end of the limb, and is filled through a plurality of filling holes of the thrombolytic device, so that the thrombolytic effect is better; meanwhile, the plurality of perfusion holes have the characteristic of high pressure resistance, and the perfusion holes can be used for perfusion and thrombolysis, and can also be used for crushing thrombus and improving the blood vessel patency rate through high-pressure injection.

The outer side wall of the far end of the outer sleeve 100 is covered with a heparin coating, and the length of the section 500 of the outer sleeve coated with the heparin coating is 30-40 cm. An e-PTFE coating is covered between the heparin coating and the outer side wall of the outer sleeve, and polyurethane is covered on the outer side wall of the outer sleeve 100 and is covalently combined with the heparin coating and the hydrophilic coating. The outer side wall of the outer sleeve 100 is covered with an anticoagulant heparin coating, which can obviously reduce the incidence rate of the formation of the mural thrombus and improve the intravascular retention time of the thrombolytic catheter. The outer side wall of the outer sleeve 100 close to the base 300 is covered with a hydrophilic coating, the length of the hydrophilic layer section 600 coated on the outer sleeve 100 is 60-100cm, and the friction force between the outer sleeve 100 and the guide catheter can be obviously reduced by covering the outer side wall of the outer sleeve 100 with the hydrophilic coating.

The outer sleeve 100 and the inner sleeve 200 both use stainless steel woven mesh as a structural body, the inner side wall and the outer side wall of the inner sleeve 200 are both covered with a layer of e-PTFE coating, and the inner side wall of the inner sleeve 200 is coated with a layer of hydrophilic coating, so that the friction force between the inner sleeve and the guide wire can be remarkably reduced.

In the embodiment of the utility model, the expanded polytetrafluoroethylene (e-PTFE) is a novel medical polymer material and is made of polytetrafluoroethylene resin by special processing methods such as stretching. White, rich in elasticity and flexibility, has a network structure formed by connecting microfine fibers, and the microfine fibers form countless pores, so that the e-PTFE can be bent at will, and has good blood compatibility and biological aging resistance, and can be used for manufacturing medical products such as artificial blood vessels, heart patches and the like.

The utility model discloses dissolve bolt catheter device's outer tube 100 and interior sleeve pipe 200 all adopt medical polyurethane to make, and the group that contains in the polyurethane macromolecule all is strong polar group for polyurethane has higher mechanical strength and oxidative stability, higher flexibility and resilience, good solvent resistance and water proofness etc.. Interventional devices require lubricious surfaces to avoid damaging body tissues during insertion and removal from the body and during movement within the body. The polyurethane is a hydrophobic material, and surface lubricity, namely a hydrophilic coating, is obtained by increasing surface polar groups through hydrophilic modification of the surface of the polyurethane. The polyurethane can obtain a hydrophilic coating through hydrophilic modification, and can also obtain a heparin coating through covalent connection with heparin after surface oxidation and carboxylation. The polyurethane and the heparin are combined by covalent bonds to heparinize the surface of the material, so that the utilization rate of the heparin and the stability of the immobilized heparin can be improved, and the mechanical property and the anticoagulation performance of the material can be effectively unified. Similarly, heparin is fixed on the inner sidewall e-PTFE of the inner tube 200 by covalent modification to form a heparin coating. The main steps are that the surface of the e-PTFE is modified by nitridized chitosan so as to have the capability of reacting with heparin, and then heparin molecules are bonded.

The distal end of the outer sheath 100 is formed with a soft tip 700, the soft tip 700 has a length of 4-6cm, the braided portions of the inner sheath 200 and the outer sheath 100 extend to the soft tip 700 to form an integral structure with the soft tip 700, and the soft tip 700 is made of polyurethane material.

The distal end and the proximal end of the outer sleeve 100 are provided with marking rings 400, and the marking rings 400 are metal rings which are opaque to X rays; specifically, marker ring 400 may be selectively disposed at soft tip 700, near the soft tip, and near the proximal end of base 300. Preferably, the number of the marker rings 400 is set to 3. Preferably, the number of the marker rings may be set to 4 or more. The relative positions of all parts of the thrombolysis catheter device on the blood vessel can be detected through the marking ring, and the thrombolysis catheter device is accurately conveyed to the position of thrombus through the guide wire, so that thrombus is accurately dissolved.

The outer side wall of the outer sleeve is provided with a protection tube 800 and a protection cover 900 connected with the protection tube at a position close to the base. The protection tube 800 and the protection cover 900 are convenient for the base to be operated specifically, so as to avoid the damage to the outer sleeve part and facilitate the operation and use of the thrombolysis device.

Although the invention has been described in detail with respect to the general description and the specific embodiments, it will be apparent to those skilled in the art that modifications and improvements can be made based on the invention. Therefore, such modifications and improvements are intended to be within the scope of the invention as claimed.

Claims

1. The utility model provides a dissolve bolt pipe device, its characterized in that, it includes interior sleeve pipe, cover and arranges in the outer tube in the interior sleeve pipe outside and fixed outer tube and interior sheathed tube base, the outer tube with there is the filling chamber between the interior sleeve pipe, the distal end of outer tube is equipped with a plurality of filling holes, be equipped with on the base with fill the entrance and interior sleeve pipe inlet port of pouring hole intercommunication, fill the chamber with interior sleeve pipe inner chamber is independent each other, does not link up each other.

2. The thrombolytic catheter device of claim 1,

the outer side wall of the far end of the outer sleeve is covered with a layer of heparin coating.

3. The thrombolytic catheter device of claim 2,

and a layer of e-PTFE coating is covered between the heparin coating and the outer side wall of the outer sleeve.

4. The thrombolytic catheter device of claim 1,

and a hydrophilic coating is covered on the outer side wall of the outer sleeve close to the base.

5. The thrombolytic catheter device of claim 1,

and the inner side wall and the outer side wall of the inner sleeve are both covered with a layer of e-PTFE coating.

6. The thrombolytic catheter device of claim 1,

and a hydrophilic coating is coated on the inner side wall of the inner sleeve.

7. The thrombolytic catheter device of claim 1,

the distal end and the proximal end of the outer sleeve are provided with marking rings.

8. The thrombolytic catheter device of claim 1,

the number of the perfusion holes is 6-12, and the interval between every two adjacent perfusion holes is 1 cm.

9. The thrombolytic catheter device of claim 1,

the distal end of the outer sleeve is formed with a soft tip, and the length of the soft tip is 4-6 cm.

10. The thrombolytic catheter device of claim 1,

be close to on the outer tube lateral wall base department is equipped with the protection tube and with the safety cover that the protection tube is connected.