CN209968386U - Ultrasonic micro-vibration polypeptide synthesizer - Google Patents
Ultrasonic micro-vibration polypeptide synthesizer Download PDFInfo
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- CN209968386U CN209968386U CN201920686744.1U CN201920686744U CN209968386U CN 209968386 U CN209968386 U CN 209968386U CN 201920686744 U CN201920686744 U CN 201920686744U CN 209968386 U CN209968386 U CN 209968386U
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Abstract
The utility model discloses an ultrasonic micro-vibration polypeptide synthesizer, which comprises a reaction tank, a water circulation unit, a gas circulation unit, a reaction tube and a controller; the reaction tank is provided with a tank cover for sealing the reaction tank, the tank cover is provided with a plurality of through holes, and the bottom of the reaction tank is provided with an ultrasonic generator; the water circulation unit comprises a water inlet, a water outlet and a water outlet; the gas circulation unit comprises a gas inlet and a gas outlet which are arranged in the middle of the reaction tank, a gas distribution pipe is arranged between the gas inlet and the gas outlet in a communicating manner, a hollow first sliding shaft is arranged on the supporting platform, and the first sliding shaft is communicated with the gas distribution pipe; the bottom of the reaction tube is tightly sleeved on the first sliding shaft, the top of the reaction tube penetrates through the through hole and extends out of the reaction tank, and a sand core is arranged in the reaction tube. The device can automatically control the temperature and humidity in the polypeptide synthesis process, greatly improves the synthesis speed, and has low cost and convenient use.
Description
Technical Field
The utility model relates to a polypeptide synthesizer, in particular to an ultrasonic micro-vibration polypeptide synthesizer.
Background
Polypeptides are a generic term for biologically active substances. Polypeptides play an extremely important role in cellular activities and are essential substances in the body. The synthesis of polypeptides is a complex process, the synthesis time is relatively long, and the synthesis speed is influenced by temperature and humidity. The general solid-state polypeptide synthesizer can not control the temperature and the humidity or can control the temperature and the humidity, but the instrument is complex and expensive and needs professional personnel to maintain.
SUMMERY OF THE UTILITY MODEL
The to-be-solved technical problem of the utility model is to provide an ultrasonic wave slight shock swings polypeptide synthesizer, its temperature, humidity that can the automatic control polypeptide synthesis in-process, very big improvement synthetic speed, with low costs, convenient to use.
In order to solve the technical problem, the utility model provides an ultrasonic micro-vibration polypeptide synthesizer, which comprises a reaction tank, a water circulation unit, a gas circulation unit, a reaction tube and a controller; the reaction tank is provided with a tank cover for sealing the reaction tank, the tank cover is provided with a plurality of through holes, and the bottom of the reaction tank is provided with an ultrasonic generator; the water circulation unit comprises a water inlet and a water outlet which are arranged at the bottom of the reaction tank and a water outlet which is arranged at the top of the reaction tank, the water inlet is communicated with a water distribution pipe which is distributed at the bottom of the reaction tank, the water distribution pipe is provided with water distribution holes, and the water inlet, the water outlet and the water outlet are respectively communicated with a valve which is in signal connection with the controller; the gas circulation unit comprises a gas inlet and a gas outlet which are arranged in the middle of the reaction tank, a gas distribution pipe is communicated between the gas inlet and the gas outlet, a plurality of support tables are arranged on the gas distribution pipe, a hollow first sliding shaft is arranged on each support table, and the first sliding shaft is communicated with the gas distribution pipe; the bottom of the reaction tube is tightly sleeved on the first sliding shaft, the top of the reaction tube penetrates through the through hole and extends out of the reaction tank, a sand core is arranged in the reaction tube, and the sand core covers the first sliding shaft.
Preferably, the water circulation unit comprises a first sensor and a second sensor which are in signal connection with the controller, the first sensor is arranged above the water outlet, the second sensor is arranged in the middle of the reaction tank, and the height of the second sensor is lower than that of the upper opening of the first sliding shaft.
Preferably, the water circulation unit comprises a third sensor in signal connection with the controller, and the third sensor is arranged below the water outlet.
Preferably, a guide sliding groove is formed in the side face of the reaction tank, a guide sliding block is arranged at the bottom of the tank cover, and the guide sliding block is inserted into the guide sliding groove.
Preferably, the bottom of the guide slider is provided with a chamfer.
Preferably, the reaction tube is a cylindrical tube, and the outer diameter of the reaction tube is consistent with the inner diameter of the through hole.
Preferably, the bottom of the reaction tube is provided with a sliding sleeve, and the sliding sleeve is tightly sleeved on the first sliding shaft.
Preferably, a washer is arranged outside the first sliding shaft.
Preferably, the tank cover is a transparent cover.
Preferably, the controller is a touch panel.
Compared with the prior art, the beneficial effects of the utility model are that:
1. the utility model discloses a set up the hydrologic cycle unit, can the temperature in the automatic control polypeptide synthesis process to ensure that the synthesis process is quick, stable.
2. The utility model discloses a set up supersonic generator, can improve the brownian motion in the synthesis to improve synthetic speed.
3. The utility model discloses a set up the pond lid, the aqueous vapor that can avoid supersonic generator oscillation to rise causes reactant surface humidity too big, and then influences reaction rate.
4. The utility model discloses a set up slide shaft one, installation that can be quick or take out the reaction tube, convenient to use is swift.
5. The utility model discloses a set up gas circulation unit and psammitolite, can be quick derive gaseous state or liquid medium, can avoid water to enter into the reaction tube simultaneously.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required to be used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
Fig. 1 is a schematic view of the internal structure of the present invention;
fig. 2 is a schematic top view of the present invention;
FIG. 3 is a schematic sectional view taken along line A-A;
fig. 4 is an enlarged schematic view of the portion C.
Wherein, the reaction tank 10, the ultrasonic generator 11, the tank cover 12, the guide chute 13, the guide slide block 14 and the chamfer angle 15 are arranged in the tank;
20-a first valve, 21-a water inlet, 22-a water distribution pipe, 220-a water distribution hole, 23-a water outlet, 24-a second valve, 25-a first sensor, 26-a second sensor, 27-a third sensor, 28-a water outlet and 29-a third valve;
30-air inlet, 31-air distribution pipe, 32-saddle, 33-sliding shaft I, 34-gasket and 35-air outlet;
40-a controller;
50-reaction tube, 51-sliding sleeve, 52-sand core.
Detailed Description
The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments obtained by a person skilled in the art without any inventive work based on the embodiments of the present invention belong to the protection scope of the present invention.
Examples
Referring to fig. 1 to 4, the utility model discloses an ultrasonic micro-vibration polypeptide synthesizer, which comprises a reaction tank 10, a water circulation unit, a gas circulation unit, a reaction tube 50 and a controller 40.
A reaction tank 10:
an ultrasonic generator 11 is arranged in the reaction tank 10. The ultrasonic generator 11 is in signal connection with the controller 40. The ultrasonic generator 11 can accelerate the brownian motion between molecules and improve the reaction speed.
The top of the reaction tank 10 is provided with a tank cover 12. The top of the tank cover 12 is provided with a plurality of through holes. The inner diameter of the through-hole coincides with the outer diameter of the reaction tube 50. The tank cover 12 can seal the whole reaction tank 10, and the top of the reaction tube 50 can penetrate through the through hole to extend out of the reaction tank 10, so that the influence of moisture oscillated by the ultrasonic generator 11 during working on the surface humidity of reactants and the reaction speed is avoided.
As a further improvement of the present invention, the tank cover 12 is a transparent cover. It is convenient to observe, maintain.
The side of the reaction tank 10 is provided with a guide chute 13. The bottom of the tank cover 12 is provided with a guide slider 14. The inner diameter of the guide link 13 corresponds to the outer diameter of the guide slide 14. The guide slide 14 can be inserted into the guide runner 13. The guide slide block 14 and the guide chute 13 can guide the covering direction of the pool cover 12, so that the reaction tube 50 can just penetrate through the through hole, and collision damage is avoided.
The bottom of the guide slider 14 is provided with a chamfer 15. The chamfer 15 can assist the insertion of the guide slide 14 into the guide runner 13.
A water circulation unit:
the water circulation unit comprises a water inlet 21, a water distribution pipe 22, a water outlet 23, a water outlet 28 and a sensor.
The water inlet 21 and the water outlet 23 are respectively arranged at two ends of the reaction tank 10. The water inlet 21 is located at the bottom of the reaction tank 10. The water outlet 23 is positioned at the top of the reaction tank 10. A water distribution pipe 22 is arranged on the water inlet 21. The water distribution pipes 22 are distributed at the bottom of the reaction tank 10. The water distribution pipe 22 is provided with water distribution holes 220. The water distribution pipe 22 can guide water with a specific temperature into the reaction tank 10, and the water outlet 23 can guide water with a lower temperature from the upper layer, so as to maintain the stable and balanced temperature of the whole reaction tank 10.
The drain port 28 is provided at the bottom of the reaction tank 10. The water outlet 28 can discharge all water in the reaction tank 10, thereby facilitating water change and cleaning.
The water inlet 21, the water outlet 23 and the water outlet 28 are respectively provided with a valve I20, a valve II 24 and a valve III 29 in a communication way. The first valve 20, the second valve 24 and the third valve 29 are all in signal connection with the controller 40. The controller 40 can control the on/off of each valve to maintain the water temperature and water level in the reaction tank 10.
The sensors include a first sensor 25, a second sensor 26 and a third sensor 27 all in signal connection with the controller 40. The first sensor 25 and the third sensor are respectively arranged above and below the water outlet 23. The second sensor 26 is arranged in the middle of the reaction tank 10. The first sensor 25 and the second sensor 26 can detect the water level in the reaction tank 10. The third sensor 27 can detect the temperature of water in the reaction tank 10.
A gas circulation unit:
the air circulation unit includes an air inlet 30, an air distribution pipe 31, and an air outlet 35.
The gas inlet 30 and the gas outlet 35 are respectively provided at both ends of the reaction tank 10. The gas inlet 30 and the gas outlet 35 are both located in the middle of the reaction tank 10. The plurality of air distribution pipes 31 are communicated between the air inlet 30 and the air outlet 35. A supporting platform 32 is arranged on the air distribution pipe 31 below each through hole. Each saddle 32 is provided with a sliding shaft one 33. The first sliding shaft 33 points to the through hole. The first sliding shaft 33 is hollow and is communicated with the gas distribution pipe 31. The height of the first sliding shaft 33 is higher than that of the second sensor 26. A washer 34 is arranged outside the first sliding shaft 33. The first sliding shaft 33 can penetrate through the reaction tube 50 to lead out redundant media. The gasket 34 can improve the sealing performance at the interface and avoid pollution caused by permeation. The gas inlet 30 can be filled with inert gas to bring the medium dropping from the reaction tube 50 to the gas outlet 35 for discharge; meanwhile, the pressure at the interface can be ensured to be larger than the water pressure, and the water is prevented from permeating into the gas distribution pipe 31 and the reaction pipe 50.
The controller 40:
the controller 40 is disposed at a side of the reaction cell 10. The controller 40 is capable of setting, adjusting and viewing the operating parameters. The controller 40 may be a touch panel.
Reaction tube 50:
the reaction tube 50 is a columnar tube. The bottom of the reaction tube 50 is provided with a sliding sleeve 51. The sliding sleeve 51 is tightly sleeved on the first sliding shaft 33. A sand core 52 is arranged above the sliding sleeve 51. The sand core 52 is capable of allowing the passage of gaseous or liquid media, but will block the passage of resin. The top opening of the reaction tube 50 protrudes out of the cell cover 12 through the through hole.
The working principle is as follows:
placing reactants in the reaction tube 50, sleeving the reaction tube 50 on the first sliding shaft 33, and then keeping the pool cover 12 covered; the controller 40 controls the ultrasonic generator 11 to work, and simultaneously controls the first valve 20 to be opened, so that water with a specific temperature is introduced into the reaction tank 10; when the water level reaches the position of the first sensor 25, water supply is stopped; when the temperature detected by the third sensor 27 is lower than the threshold temperature, the controller 40 controls the first valve 20 and the second valve 24 to be opened, and the water in the reaction tank 10 is replaced to maintain the temperature stability; when the reaction tube 50 needs to be replaced, the controller 40 controls the third valve 29 to open and drain water outwards, and when the water level reaches the second sensor 26 position, the water drainage is stopped, and the reaction tube 50 can be pulled out for replacement.
The embodiment needs to be supplemented with that: the utility model discloses constitute by concrete hardware structures such as controller, sensor, valve, supersonic generator, partial hardware has the participation of software program at the operation in-process, and the software program of supplementary local operation is current software program that can duplicate, does not constitute the innovation point of this application.
The previous description of the disclosed embodiments is provided to enable any person skilled in the art to make or use the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention. Thus, the present invention is not intended to be limited to the embodiments shown herein but is to be accorded the widest scope consistent with the principles and novel features disclosed herein.
Claims (10)
1. An ultrasonic micro-oscillation polypeptide synthesizer is characterized by comprising a reaction tank, a water circulation unit, a gas circulation unit, a reaction tube and a controller;
the reaction tank is provided with a tank cover for sealing the reaction tank, the tank cover is provided with a plurality of through holes, and the bottom of the reaction tank is provided with an ultrasonic generator;
the water circulation unit comprises a water inlet and a water outlet which are arranged at the bottom of the reaction tank and a water outlet which is arranged at the top of the reaction tank, the water inlet is communicated with a water distribution pipe which is distributed at the bottom of the reaction tank, the water distribution pipe is provided with water distribution holes, and the water inlet, the water outlet and the water outlet are respectively communicated with a valve which is in signal connection with the controller;
the gas circulation unit comprises a gas inlet and a gas outlet which are arranged in the middle of the reaction tank, a gas distribution pipe is communicated between the gas inlet and the gas outlet, a plurality of support tables are arranged on the gas distribution pipe, a hollow first sliding shaft is arranged on each support table, and the first sliding shaft is communicated with the gas distribution pipe;
the bottom of the reaction tube is tightly sleeved on the first sliding shaft, the top of the reaction tube penetrates through the through hole and extends out of the reaction tank, a sand core is arranged in the reaction tube, and the sand core covers the first sliding shaft.
2. The ultrasonic micro-oscillation polypeptide synthesizer as claimed in claim 1, wherein the water circulation unit comprises a first sensor and a second sensor both connected with the controller by signals, the first sensor is arranged above the water outlet, the second sensor is arranged in the middle of the reaction tank, and the height of the second sensor is lower than that of the upper opening of the first sliding shaft.
3. The ultrasonic micro-oscillation polypeptide synthesizer of claim 2, wherein the water circulating unit comprises a third sensor in signal connection with the controller, and the third sensor is arranged below the water outlet.
4. The ultrasonic micro-oscillation polypeptide synthesizer as claimed in claim 1, wherein a guide sliding groove is provided on the side surface of the reaction tank, and a guide sliding block is provided at the bottom of the tank cover and inserted in the guide sliding groove.
5. The ultrasonic micro-oscillation polypeptide synthesizer of claim 4, wherein the bottom of the guide slide block is provided with a chamfer.
6. The ultrasonic micro-oscillation polypeptide synthesizer of claim 1, wherein the reaction tube is a cylindrical tube, and the outer diameter of the reaction tube is consistent with the inner diameter of the through hole.
7. The ultrasonic micro-oscillation polypeptide synthesizer of claim 6, wherein the bottom of the reaction tube is provided with a sliding sleeve, and the sliding sleeve is tightly sleeved on the first sliding shaft.
8. The ultrasonic micro-oscillation polypeptide synthesizer of claim 7, wherein a gasket is disposed outside the slide shaft.
9. The ultrasonic micro-oscillation polypeptide synthesizer of claim 1, wherein the tank cover is a transparent cover.
10. The ultrasonic micro-shaking polypeptide synthesizer of claim 1, wherein the controller is a touch panel.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920686744.1U CN209968386U (en) | 2019-05-13 | 2019-05-13 | Ultrasonic micro-vibration polypeptide synthesizer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920686744.1U CN209968386U (en) | 2019-05-13 | 2019-05-13 | Ultrasonic micro-vibration polypeptide synthesizer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209968386U true CN209968386U (en) | 2020-01-21 |
Family
ID=69262195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201920686744.1U Expired - Fee Related CN209968386U (en) | 2019-05-13 | 2019-05-13 | Ultrasonic micro-vibration polypeptide synthesizer |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN209968386U (en) |
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2019
- 2019-05-13 CN CN201920686744.1U patent/CN209968386U/en not_active Expired - Fee Related
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| Date | Code | Title | Description |
|---|---|---|---|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200121 Termination date: 20210513 |
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| CF01 | Termination of patent right due to non-payment of annual fee |