CN209916279U

CN209916279U - Fixer for experimental mouse

Info

Publication number: CN209916279U
Application number: CN201920347155.0U
Authority: CN
Inventors: 张梦迪; 刘翠艳; 韩春杨; 梁珊; 张�荣
Original assignee: Anhui Agricultural University AHAU
Current assignee: Anhui Agricultural University AHAU
Priority date: 2019-03-19
Filing date: 2019-03-19
Publication date: 2020-01-10
Anticipated expiration: 2029-03-19

Abstract

The utility model discloses a fixer for experimental mice, which comprises a bottom plate, three adjustable belts arranged in parallel, two wide through-hole grooves which are arranged in parallel, are arranged at the top of the bottom plate, are symmetrical about the center of the bottom plate and are used for placing four limbs of the mice, and four limiting components for fixing the four limbs of the mice; the adjustable belt is installed on the top of the base plate between the two wide through-hole grooves, the extending direction of the adjustable belt is perpendicular to the extending direction of the wide through-hole grooves, and two limiting assemblies are movably installed on the side wall, deviating from the center of the base plate, in each wide through-hole groove. Compared with the prior art, the utility model has the following advantages: the utility model can realize the respective fixation of the four limbs of the mouse without damaging the four limbs of the mouse; the process of binding and unbinding the mouse is convenient, time-saving and labor-saving; the test of a plurality of parts such as eyeball blood collection, intraperitoneal injection and the like can be completed on the same fixator.

Description

Fixer for experimental mouse

Technical Field

The utility model relates to an animal experiment utensil field especially relates to a fixer for experimental mouse.

Background

Animal experiments refer to scientific research using animals in laboratories to gain new knowledge about biology, medicine, etc. or to solve specific problems. The mouse is a common laboratory animal, and because the mouse is small in size, the mouse needs to be carefully grabbed and cannot be injured by over-exertion; the skin of the neck of the mouse needs to be grasped by the index finger and the thumb of the left hand because the mouse is flexible and multi-mobile, caution is needed when grasping the neck, and otherwise, an operator can be easily bitten by the mouse; a common laboratory fixing device fixes a mouse on a wooden plate with nails, and four limbs are tied on four nails, so that the process is complicated.

The existing mouse fixator is inconvenient for fixing the four limbs of the mouse, is easy to damage the four limbs of the mouse, and is troublesome and long in time for fixing the four limbs of the mouse; meanwhile, the processes of binding and unbinding the mouse are complicated, and time and labor are wasted; and the head of the mouse is completely fixed, so that the tests of a plurality of parts such as eyeball blood collection, intraperitoneal injection, tail breaking and the like cannot be completed simultaneously.

SUMMERY OF THE UTILITY MODEL

The utility model discloses the technical problem that will solve lies in: the existing mouse fixer is inconvenient to fix the four limbs of the mouse, easily damages the four limbs of the mouse, and is troublesome and time-consuming to fix the four limbs of the mouse. Therefore, the fixing device for the experimental mouse is provided.

The utility model discloses a solve above-mentioned technical problem through following technical scheme:

a fixer for an experimental mouse comprises a bottom plate, three adjustable belts arranged in parallel, two wide through hole grooves which are arranged in parallel, are arranged at the top of the bottom plate, are symmetrical relative to the center of the bottom plate and are used for placing four limbs of the mouse, and four limiting assemblies used for fixing the four limbs of the mouse; the adjustable belt is installed on the top of the base plate between the two wide through-hole grooves, the extending direction of the adjustable belt is perpendicular to the extending direction of the wide through-hole grooves, and two limiting assemblies are movably installed on the side wall, deviating from the center of the base plate, in each wide through-hole groove. Can place the mouse on the bottom plate top, push down the mouse fast and fix through adjustable belt, the four limbs of mouse can stretch into wide hole groove to fix the mouse four limbs in wide hole groove through spacing subassembly, realize the further fixed of mouse.

Preferably, each limiting assembly comprises a plurality of adjusting holes and a pressing bolt; the adjusting holes are formed in the bottom plate, one end of each adjusting hole is communicated with the corresponding wide through hole groove, the other end of each adjusting hole is communicated with the outer space of the bottom plate, and the adjusting holes in the same limiting assembly are arranged in parallel; the pressing bolt comprises a screw rod and an arc-shaped body, the screw rod is screwed in the adjusting hole, the arc-shaped body is arranged in the wide through hole groove, one end of the screw rod is detachably connected with the center of the convex surface of the arc-shaped body, and the other end of the screw rod is arranged on the outer side of the bottom plate; the axial direction of the screw is perpendicular to the extending direction of the wide through hole groove. The four limbs of the mouse are respectively fixed in the concave surface of each arc-shaped body, the tightness between the arc-shaped bodies and the four limbs of the mouse can be adjusted through the rotation of the screw rods, and the mouse fixing device can also be suitable for fixing mice of different sizes.

Preferably, each adjustable belt is composed of a belt body and an adjusting buckle, two groups of through hole groups which are symmetrical relative to the center of the base plate and are parallel to the wide through hole grooves are formed in the base plate between the two wide through hole grooves, each through hole group is composed of a through hole and a narrow through hole groove, the through holes in the same group are formed in the base plate corresponding to the end portions of the corresponding narrow through hole grooves, two ends of one of the three belt bodies penetrate through one through hole respectively and are arranged below the base plate and are connected through the adjusting buckle corresponding to the through hole, and two ends of the other two belt bodies penetrate through one narrow through hole groove respectively and are arranged below the base plate and are connected through the adjusting buckle corresponding to the narrow through hole groove. The belt body can freely be pulled in adjusting the buckle so that the degree of compression between the belt body and the mouse can be adjusted, and therefore the belt body can also be suitable for fixing mice with different body types.

Preferably, the adjusting buckles are two fixing buckles, and each fixing buckle comprises an upper iron sheet, a lower iron sheet and a rotating shaft core; the bottom parts of the two sides of the upper iron sheet are respectively and vertically provided with arc parts, one side of the bottom part of the upper iron sheet between the two arc parts is provided with a row of sawteeth, and the two arc parts close to one side of the sawteeth are respectively provided with an upper round hole corresponding to the two ends of the rotating shaft core; the tops of two sides of the lower iron sheet are respectively and vertically provided with a vertical part, and the two vertical parts are respectively provided with a lower round hole corresponding to the rotating shaft core; the upper iron sheet is arranged right above the lower iron sheet and is rotationally connected with the lower iron sheet through the rotating shaft core, the two upper round holes and the two lower round holes; two ends of each belt body correspond to one fixing buckle respectively, and each end part penetrates through one end, provided with a row of sawteeth, of the corresponding fixing buckle and penetrates out of the other end opposite to the end and is arranged on the outer side of the fixing buckle; each fixed buckle is fixedly arranged at the bottom of the bottom plate. The width of belt body is half for fixed buckle width, makes it can adjust best fixed position according to mouse size on fixed buckle.

Preferably, the operation hole is arranged on the bottom plate which is far away from the position between the two ends of the through hole in the same name end of the two narrow through hole grooves. The operation hole is mainly arranged to facilitate the intraperitoneal injection of the mouse.

Preferably, the rubber layer is coated on the inner wall of the wide through hole groove, and the arc-shaped body is made of rubber. The inner wall of the wide through hole groove of the rubber layer and the arc-shaped body made of rubber can increase friction and buffering on four limbs of the mouse, so that the four limbs of the mouse can be prevented from sliding out of the rubber layer and being damaged.

Preferably, the device further comprises two brackets which are parallel to the wide through-hole grooves and fixedly arranged at the bottom of the bottom plate, and the two wide through-hole grooves are arranged between the two brackets. The support has certain height, can make to have certain interval between bottom plate bottom surface and the ground, conveniently carries out the operation experiment to each position of mouse.

Compared with the prior art, the utility model has the following advantages: the utility model can realize the respective fixation of the four limbs of the mouse, and can more conveniently and stably test the four limbs of the mouse on the premise of not damaging the four limbs of the mouse; the process of binding and unbinding the mouse is convenient, time-saving and labor-saving; the device can complete the tests of a plurality of positions such as eyeball blood sampling, intraperitoneal injection, tail breaking and the like on the same fixator, and has strong practicability.

Drawings

FIG. 1 is a schematic top view of the present invention;

FIG. 2 is a schematic view of the bottom of the present invention with the adjustment holes and the hold-down bolts removed;

FIG. 3 is a schematic structural view of the fixing clip;

FIG. 4 is a schematic structural view of an upper iron sheet;

FIG. 5 is a schematic view of the structure of the lower iron plate and the shaft core;

FIG. 6 is a schematic view of the construction of the hold-down bolt;

FIG. 7 is a schematic view of the structure of FIG. 2 from A-A to the open position of the first retaining buckle;

fig. 8 is a schematic structural view of a-a in fig. 2 showing a closed state of the first fixing buckle.

Detailed Description

The embodiments of the present invention will be described in detail below, and the present embodiment is implemented on the premise of the technical solution of the present invention, and a detailed implementation manner and a specific operation process are given, but the scope of the present invention is not limited to the following embodiments.

Example 1

As shown in fig. 1, 2 and 6, the fixer for the experimental mouse comprises a bottom plate 1, three adjustable belts arranged in parallel, two wide through-hole grooves 13 which are arranged in parallel, are arranged at the top of the bottom plate 1, are symmetrical about the center of the bottom plate and are used for placing the limbs of the mouse, and four limiting components for fixing the limbs of the mouse; the three adjustable belts are all installed on the top of the bottom plate 1 between the two wide through-hole grooves 13, the extending directions of the adjustable belts are perpendicular to the extending directions of the wide through-hole grooves 13, and two limiting assemblies are movably installed on the side wall, deviating from the center of the bottom plate 1, in each wide through-hole groove 13. Can place the mouse on 1 top of bottom plate, push down the mouse fast and fix through adjustable belt, the four limbs of mouse can stretch into wide thru hole groove 13 to fix the mouse four limbs in wide thru hole groove 13 through spacing subassembly, realize the further fixed of mouse.

Each limiting assembly comprises a plurality of adjusting holes 15 and a pressing bolt 5; the adjusting holes 15 are formed in the bottom plate 1, one end of each adjusting hole is communicated with the corresponding wide through hole groove 13, the other end of each adjusting hole is communicated with the outer space of the bottom plate 1, and the adjusting holes 15 in the same limiting assembly are arranged in parallel; the pressing bolt 5 comprises a screw rod 51 and an arc-shaped body 52, the screw rod 51 is screwed in the adjusting hole 15, the arc-shaped body 52 is arranged in the wide through hole groove 13, one end of the screw rod 51 is detachably connected with the center of the convex surface of the arc-shaped body 52, and the other end of the screw rod 51 is arranged on the outer side of the bottom plate 1; the axial direction of the screw 51 is perpendicular to the extending direction of the wide through hole 13. Particularly, four limbs of the mouse are respectively fixed in the concave surface of each arc-shaped body 52, the tightness between the arc-shaped bodies 52 and the four limbs of the mouse can be adjusted through the rotation of the screw 51, and the mouse fixing device can also be suitable for fixing the mice with different sizes and body types; the adjusting holes 15 are generally multiple, and the fixing position of the pressing bolt 5 can be adjusted according to mice with different sizes.

Each adjustable belt is composed of a belt body 4 and an adjusting buckle, two groups of through hole groups which are symmetrical relative to the center of the base plate 1 and are parallel to the wide through hole grooves 13 are arranged on the base plate 1 between the two wide through hole grooves 13, each through hole group is composed of a through hole 14 and a narrow through hole groove 2, the through holes 14 in the same group are arranged on the base plate 1 corresponding to the end parts of the corresponding narrow through hole grooves 2, two ends of one of the three belt bodies 4 respectively penetrate through one through hole 14 and are arranged below the base plate 1 and are connected through the adjusting buckle corresponding to the through hole 14, and two ends of the other two belt bodies 4 respectively penetrate through one narrow through hole groove 2 and are arranged below the base plate 1 and are connected through the adjusting buckle corresponding to the narrow through hole groove. The belt body can freely be pulled in adjusting the buckle so that the degree of compression between the belt body and the mouse can be adjusted, and therefore the belt body can also be suitable for fixing mice with different body types.

As shown in fig. 3, 4 and 5, the adjusting buckle is specifically two fixing buckles 3, and each fixing buckle 3 includes an upper iron sheet 31, a lower iron sheet 32 and a rotating shaft core 33; the bottom parts of the two sides of the upper iron sheet 31 are respectively and vertically provided with arc parts 311, one side of the bottom part of the upper iron sheet 31 between the two arc parts 311 is provided with a row of saw teeth 312, and the two arc parts 311 at one side close to the saw teeth 312 are respectively provided with an upper round hole 313 corresponding to the two ends of the rotating shaft core 33; the tops of the two sides of the lower iron sheet 32 are respectively and vertically provided with vertical parts 321, and the two vertical parts 321 are respectively provided with a lower round hole 322 corresponding to the rotating shaft core 33; the upper iron sheet 31 is arranged right above the lower iron sheet 32 and is rotatably connected with the lower iron sheet through a rotating shaft core 33, two upper round holes 313 and two lower round holes 322; two ends of each belt body correspond to one fixing buckle respectively, and each end part penetrates through one end, provided with a row of sawteeth, of the corresponding fixing buckle and penetrates out of the other end opposite to the end and is arranged on the outer side of the fixing buckle; each fixed buckle is fixedly arranged at the bottom of the bottom plate. The width of belt body is half for fixed buckle width, makes it can adjust best fixed position according to mouse size on fixed buckle. The fixing between the fixing buckle 3 and the bottom plate 1 is realized by the saw teeth 312 side close to the edge of the through hole 14 or the narrow through hole slot 2 and welding the upper iron sheet 31 on the bottom surface of the bottom plate 1.

In this embodiment, the bottom plate 1 is an iron plate having a length of 15cm and a width of 7cm, and the through holes 14 have a length of 0.3cm and a width of 0.3 cm; the narrow through hole groove 2 is 3.8cm long and 0.3cm wide; the wide through hole groove 13 is 7cm long and 1cm wide; the height of the fixed buckle 3 is 0.5cm, and the sizes of the fixed buckles sequentially arranged from the through holes to the narrow through hole grooves are respectively as follows: the length of the fixing rod is 0.5cm, and the fixing rod is used for fixing the neck of a mouse; the length of the fixing support is 1.3cm, and the fixing support is used for fixing the chest of a mouse; the length of the mouse fixing part is 1.6cm, and the mouse fixing part is used for fixing the mouse; through one of the three fixing buckles 3 arranged at the bottom of the bottom plate 1 between the through hole 14 and the wide through hole groove 13 and the other two fixing buckles arranged at the bottom of the bottom plate 1 between the narrow through hole groove 2 and the wide through hole groove 13 at intervals, the distance between the three fixing buckles 3 can be properly adjusted according to actual conditions, and the neck, the chest and the recommended part of the mouse are sequentially fixed, so that the experiments of the eyeball blood sampling, the tail breaking and other parts of the mouse can be realized.

As shown in fig. 7 in particular, iron sheet 32 is turned up along pivot core 33, then can make and appear the space down between iron sheet 32 and sawtooth 312, belt body 4 can be twitched this moment, make belt body 4 be in to being in the fixed most suitable position of mouse on bottom plate 1 top surface, then compress tightly iron sheet 32 down, as shown in fig. 8, make belt body 4 between iron sheet 32 and the sawtooth 312 down compressed tightly, thereby realize belt body 4's fixing, if need change the mouse in the experiment etc. only, need realize belt body 4's pine or tightness, convenient and fast through the aforesaid mode. The width of the belt 4 body is half of the width of the fixed buckle 3, so that the position of the belt 4 body can be adjusted according to the size of a mouse on the fixed buckle 3.

The operation hole 12 is arranged on the bottom plate 1 between two ends far away from the through hole 14 in the same-name ends of the two narrow through hole grooves 2. The operation hole is mainly convenient for the mouse to carry out intraperitoneal injection; in this embodiment, the length and width of the operation hole 12 are parallel to the width and length of the bottom plate 1, specifically, the length is 1.4cm, and the width is 1 cm.

The inner wall of the wide through hole groove 13 is coated with a rubber layer, and the arc-shaped body 52 is made of rubber. The inner wall of the wide through hole groove of the rubber layer and the arc-shaped body made of rubber can increase friction and buffering on four limbs of the mouse, so that the four limbs of the mouse can be prevented from sliding out of the rubber layer and being damaged. Specifically, the rubber layer 131 coated on the inner wall of the wide perforated groove 13 is an adhesive rubber strip, so that the rubber layer 131 can be replaced after being worn out.

The structure also comprises two brackets 11 which are parallel to the wide through hole grooves 13 and are fixedly arranged at the bottom of the bottom plate 1, and the two wide through hole grooves 13 are arranged between the two brackets 11. The support has certain height, can make to have certain interval between bottom plate bottom surface and the ground, conveniently carries out the operation experiment to each position of mouse.

Experiment mouse fixer single operatable, fixed accurate stable, operator's safety is guaranteed to very big degree, still can carry out the regulation fixed to the individual difference of mouse. The device can be used for testing a plurality of parts of the head, the abdomen, the four limbs and the tail, overcomes the defects that different tests cannot be completed by the same mouse fixer at present and the injury risk exists, can be used for mouse tail vein injection, mouse tail vein blood sampling, mouse tail tenderness, tail scalding pain or electric irritation pain tests, mouse toe swelling anti-inflammatory tests and various tests needing to fix the mouse in a waking state, and has strong practicability; and the fixer is small and exquisite and convenient to carry, and can bring great convenience to experimenters.

The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.

Claims

1. The utility model provides a fixer for experimental mouse, includes bottom plate (1) and three parallel arrangement's adjustable belt, its characterized in that: the mouse fixing device also comprises two wide through hole grooves (13) which are arranged in parallel, arranged at the top of the bottom plate (1), symmetrical about the center of the bottom plate and used for placing four limbs of a mouse, and four limiting components used for fixing the four limbs of the mouse; three adjustable belt is all installed two bottom plate top between wide hole groove (13) of passing through, just the extending direction of adjustable belt with the extending direction mutually perpendicular of wide hole groove (13), every deviate from in the wide hole groove (13) equal movable mounting has two on the lateral wall at bottom plate (1) center spacing subassembly.

2. The holder for laboratory mice according to claim 1, wherein: each limiting assembly comprises a plurality of adjusting holes (15) and a pressing bolt (5); the adjusting holes (15) are formed in the bottom plate (1), one end of each adjusting hole is communicated with the corresponding wide through hole groove (13), the other end of each adjusting hole is communicated with the outer space of the bottom plate (1), and the adjusting holes (15) in the same limiting assembly are arranged in parallel; the pressing bolt (5) comprises a screw rod (51) and an arc-shaped body (52), the screw rod (51) is in threaded connection with the adjusting hole (15), the arc-shaped body (52) is arranged in the wide through hole groove (13), one end of the screw rod (51) is detachably connected with the center of the convex surface of the arc-shaped body (52), and the other end of the screw rod is arranged on the outer side of the bottom plate (1); the axial direction of the screw (51) is perpendicular to the extending direction of the wide through hole groove (13).

3. The holder for laboratory mice according to claim 2, wherein: each adjustable belt is composed of a belt body (4) and an adjusting buckle, two groups of through hole groups which are symmetrical relative to the center of the base plate (1) and are parallel to the wide through hole grooves (13) are arranged on the base plate (1) between the two wide through hole grooves (13), each through hole group is composed of a through hole (14) and a narrow through hole groove (2), the through holes (14) in the same group are arranged on the base plate (1) corresponding to the end parts of the corresponding narrow through hole grooves (2), two ends of one of the three belt bodies (4) respectively penetrate through one through hole (14) and are arranged below the base plate (1) and are connected with the base plate through the adjusting buckle corresponding to the through hole, two ends of the other two belt bodies (4) respectively penetrate through the narrow through hole groove (2) and are arranged below the bottom plate (1) and are connected through the corresponding adjusting buckles.

4. The holder for laboratory mice according to claim 3, wherein: the adjusting buckles are two fixing buckles (3), and each fixing buckle (3) comprises an upper iron sheet (31), a lower iron sheet (32) and a rotating shaft core (33); the bottom parts of the two sides of the upper iron sheet (31) are respectively and vertically provided with arc parts (311), one side of the bottom part of the upper iron sheet (31) between the two arc parts (311) is provided with a row of saw teeth (312), and the two arc parts (311) close to one side of the saw teeth (312) are respectively provided with an upper round hole (313) corresponding to the two ends of the rotating shaft core (33); the tops of two sides of the lower iron sheet (32) are respectively and vertically provided with vertical parts (321), and the two vertical parts (321) are respectively provided with a lower round hole (322) corresponding to the rotating shaft core (33); the upper iron sheet (31) is arranged right above the lower iron sheet (32) and is rotatably connected with the lower iron sheet through a rotating shaft core (33), two upper round holes (313) and two lower round holes (322);

two ends of each belt body correspond to one fixing buckle respectively, and each end part penetrates through one end, provided with a row of sawteeth, of the corresponding fixing buckle and penetrates out of the other end opposite to the end and is arranged on the outer side of the fixing buckle; each fixed buckle is fixedly arranged at the bottom of the bottom plate.

5. The holder for laboratory mice according to claim 4, wherein: the operation hole (12) is formed in the bottom plate (1) between two ends, far away from the through holes (14), of the homonymous ends of the two narrow through hole grooves (2).

6. The holder for laboratory mice according to claim 5, wherein: the inner wall of the wide through hole groove (13) is coated with a rubber layer, and the arc-shaped body (52) is made of rubber.

7. The holder for laboratory mice according to claim 6, wherein: the novel bottom plate is characterized by further comprising two supports (11) which are parallel to the wide through hole grooves (13) and fixedly mounted at the bottom of the bottom plate (1), wherein the two wide through hole grooves (13) are arranged between the two supports (11).