CN209858594U - Incubation groove component of biochemical analyzer and biochemical analyzer - Google Patents

Incubation groove component of biochemical analyzer and biochemical analyzer Download PDF

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Publication number
CN209858594U
CN209858594U CN201920359928.7U CN201920359928U CN209858594U CN 209858594 U CN209858594 U CN 209858594U CN 201920359928 U CN201920359928 U CN 201920359928U CN 209858594 U CN209858594 U CN 209858594U
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China
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biochemical analyzer
linear channel
detection
site
incubator
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CN201920359928.7U
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石振希
时冉
王东元
武通园
叶友军
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Shenzhen City Live Near Diagnosis Instrument Co Ltd Waterbed
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Shenzhen City Live Near Diagnosis Instrument Co Ltd Waterbed
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Abstract

The utility model belongs to the technical field of biochemical analyzer, a biochemical analyzer's incubation groove subassembly and biochemical analyzer is provided, set up puncture position and application of sample position with the straight line channel intercommunication along the interval of straight line channel direction through the higher authority that has the incubation groove of straight line channel in inside, and set up the detection position with the straight line channel intercommunication in the side of incubation groove, and one side at straight line channel sets up the current actuating mechanism of chip cartridge that can drive interior sealing of disposable test reagent, and then effectively avoid the production of uncork validity period problem and the operation of "calibration" process, thereby make the detection process that possesses the biochemical analyzer of this incubation groove subassembly instant simple, it improves to detect the precision.

Description

Incubation groove component of biochemical analyzer and biochemical analyzer
Technical Field
The utility model belongs to the technical field of biochemical analysis appearance, especially, relate to a biochemical analysis appearance's incubation groove subassembly and biochemical analysis method.
Background
At present, a circular ring-shaped incubation groove is commonly used in a biochemical analyzer for placing a reagent bottle and a reaction cup. Wherein, the reagent bottle is filled with a plurality of human reagent quantities for detecting a plurality of samples. When a specific sample is detected, the reagent bottle is opened, and then the reagent is sucked by the reagent sucking device to be uniformly mixed with the sample in the reaction cup for detection.
SUMMERY OF THE UTILITY MODEL
Although the circular ring-shaped incubation groove of the existing biochemical analyzer can realize sample detection, the circular ring-shaped incubation groove needs to be capable of placing a plurality of reaction cups and reagent bottles containing a large amount of reagent for measurement so as to meet the requirement of multi-part test because the market orientation of the existing biochemical analyzer with the circular ring-shaped incubation groove is generally oriented to large medical institutions. However, practice shows that the reagent can not be used up after the reagent bottle is opened, so that the problem of bottle opening validity period is caused, namely, the reagent remained after the bottle is opened is reused after a certain time, and the sample detection precision can be reduced. In addition, the independent presence of the cuvettes and reagent bottles in the annular incubation chamber is often a significant reason for the need for complex "calibration" procedures for sample testing. The calibration requires professional operation and the operation flow is complex, so that the biochemical analyzer of the annular incubation groove cannot be popularized in small medical institutions such as community hospitals.
In conclusion, the circular ring-shaped incubation groove of the conventional biochemical analyzer has the defects of complex detection process of the biochemical analyzer, easy reduction of detection precision and the like.
The utility model provides an incubation groove subassembly of biochemical analyzer to solve the above-mentioned defect of the ring shape incubation groove of current biochemical analyzer, this biochemical analyzer's incubation groove subassembly includes:
an incubation tank with a linear channel inside; a puncture position and a sample adding position which are communicated with the linear channel are arranged on the incubation groove at intervals along the direction of the linear channel; the side surface of the incubation groove is provided with a detection position communicated with the linear channel for biochemical detection; and one side of the linear channel is provided with a driving mechanism capable of driving the chip box internally sealed with the disposable test reagent to pass.
Further, the driving mechanism drives the chip box to pass by driving a clamping and limiting mechanism to move.
Furthermore, the clamping and limiting mechanism comprises a limiting block and a front sliding block and a rear sliding block which are connected through a spring; the limiting block limits the chip box; one side of the front and rear sliding blocks is provided with a rotary hook capable of rotatably clamping the chip box, and one side of the front and rear sliding blocks is connected with the driving mechanism.
Further, the incubation tank is of a strip structure.
Further, an in-place sensor for sensing position information of the chip cartridge is further provided at one side of the incubation slot.
Further, the in-position sensor is disposed near an entrance of the cartridge in the linear channel.
Further, the piercing location is further from the cartridge inlet of the linear channel than the sample loading location is from the cartridge inlet of the linear channel.
Furthermore, a chip box identification position is arranged on one side of the incubation groove; the chip box identification position is communicated with the linear channel, and the distance between the chip box identification position and the linear channel is longer than the distance between the puncture position and the chip box inlet of the linear channel.
Further, the detection position is arranged between the chip box identification position and the puncture position and comprises a transmission detection position and/or a scattering detection position.
Specifically, the side wall of the chip box corresponding to the detection position is made of a light-transmitting material.
The utility model provides an incubation groove subassembly of biochemical analyzer, set up puncture position and application of sample position with the straight line passageway intercommunication along the interval of straight line passageway direction through the higher authority that has the incubation groove of straight line passageway in inside, and set up the detection position with the straight line passageway intercommunication in the side of incubation groove, and set up the current actuating mechanism of chip cartridge that has disposable test reagent in can driving in one side of straight line passageway, and then effectively avoid the production of uncork valid period problem and the operation of "calibration" process, thereby make the detection process that possesses the biochemical analyzer of this incubation groove subassembly instant simple, it improves to detect the precision.
Drawings
FIG. 1 is a schematic diagram of an embodiment of an incubator assembly of a biochemical analyzer;
FIG. 2 is a schematic view showing the construction of an incubator assembly of a biochemical analyzer according to a modified embodiment;
FIG. 3 is a schematic view showing the structure of an incubator assembly of a biochemical analyzer according to a modified embodiment.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention. In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus, should not be construed as limiting the present invention.
Furthermore, in the description of the present invention, unless explicitly stated or limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; the two elements may be directly connected or indirectly connected through an intermediate medium, or may be communicated with each other inside the two elements, or may be wirelessly connected or wired connected. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.
Furthermore, the technical features mentioned in the different embodiments of the invention described below can be combined with each other as long as they do not conflict with each other.
In the following, the present invention proposes some preferred embodiments to teach those skilled in the art to implement.
FIG. 1 is a schematic structural view of an incubator assembly of a biochemical analyzer according to an embodiment, showing an incubator assembly of a biochemical analyzer, the incubator assembly of the biochemical analyzer including:
referring to fig. 1, an incubation well 205 having a linear channel therein; a puncture position 2052 and a sample adding position 2051 which are communicated with the linear channel are arranged on the upper surface of the incubation groove 205 at intervals along the direction of the linear channel; the side surface of the incubation groove 205 is provided with detection positions (2054, 2055) communicated with the linear channel for biochemical detection; one side of the linear channel is provided with a driving mechanism 203 which can drive a chip box 204 filled with disposable test reagents to pass through.
In this embodiment, the puncturing positions 2052 and the sample adding positions 2051 communicated with the linear channel are arranged on the incubation groove 205 with the linear channel at intervals along the direction of the linear channel, the detection positions (2054, 2055) communicated with the linear channel are arranged on the side surface of the incubation groove 205, and the driving mechanism 203 capable of driving the chip box 204 internally sealed with the disposable test reagent to pass is arranged on one side of the linear channel, so that the problems of the effective period of the decapsulation and the operation of the 'calibration' process are effectively avoided, and the detection process of the biochemical analyzer with the incubation groove 205 assembly is instant and simple and the detection precision is improved.
It should be noted that, since the testing reagent sealed in the chip box 204 is a disposable reagent for a single person, the testing reagent is sealed in the chip box 204 in advance through the sealing film for disposable measurement, and meanwhile, the reagent sealed in advance is calibrated through a special "calibration" process, and the complicated operation of reagent "calibration" is not required when the testing reagent is used, so that the detection process of the biochemical analyzer having the incubation groove 205 assembly is simple in time. Wherein, because the test reagent is the disposable single reagent that uses of sealing up, consequently can effectively avoid the problem of the expiration date of opening the bottle, not lead to the measuring accuracy to reduce when using again because of reagent remains.
In addition, when the sample is detected and analyzed by using the incubator assembly of the biochemical analyzer in this embodiment, the chip cartridge 204 is put in from the inlet of the chip cartridge 204 in the linear channel, the chip cartridge 204 is driven to pass through the linear channel by the driving mechanism 203, the puncture of the sealing film of the chip cartridge 204 by the puncture site 2052 is received, the sample is loaded to the punctured chip cartridge 204 by the sample loading site 2051, and the biochemical reaction value of the reactant mixed with the sample and the reagent is analyzed by the detection sites (2054, 2055), so that the sample can be tested efficiently and simply in real time.
In addition, compared with the prior art in which a reagent bottle and a reaction cup are placed in an annular incubation groove, and a biochemical analyzer for detecting a plurality of samples is provided with a plurality of human reagents in the reagent bottle, the biochemical analyzer of the incubation groove assembly provided by the embodiment has the advantages of instant simplicity in detection process, relatively high detection accuracy and the like.
In particular, the incubation slot 205 may be provided as a strip configuration. The incubation groove 205 of rectangular structure does benefit to and sets up the straight line passageway, is favorable to setting up puncture position 2052, application of sample position 2051 and detecting position (2054, 2055) along the straight line passageway for other mechanisms of biochemical analyzer can set up along the incubation groove 205 of rectangular structure, thereby reach the mechanism's position of concentrating and in order to reduce biochemical analyzer complete machine volume effect.
It should be noted that biochemical detection is a specific detection method, that is, a method of irradiating a sample through a side wall of a chip case with light to perform detection. Therefore, the portion of the sidewall of the chip cartridge 204 opposite the detection sites (2054, 2055) needs to be light permeable so that light can penetrate to illuminate the sample to be detected. As the side surface of the incubation groove 205 is provided with the detection positions (2054, 2055) communicated with the linear channel, a light path can be established, and the biochemical analysis of the sample can be realized. Meanwhile, the light path emits light to irradiate the side wall of the chip box 204, the light irradiates the sample through the light-permeable side wall, and then the light is detected through transmittance turbidimetry and/or scattering turbidimetry, so that the sample detection result is obtained.
The incubator 205 has a function of keeping the reactant at a constant temperature and providing an appropriate reaction temperature, and may be specifically composed of a heat generating device, a temperature sensor, a temperature adjusting device, and the like.
Based on the disclosure of the embodiment in fig. 1, fig. 2 is a schematic structural diagram of an incubator assembly of a biochemical analyzer according to a modified embodiment, which shows a holding and limiting mechanism of the incubator assembly of the biochemical analyzer.
Referring to fig. 1-2, the driving mechanism 203 drives the chip box 204 to pass by driving the clamping and limiting mechanism to move. Specifically, the clamping and limiting mechanism comprises a limiting block 2020 and front and rear sliders (2021, 2023) connected through a spring; the limiting block 2020 limits the chip cartridge 204; one side of the front and back sliders (2021, 2023) is provided with a rotary hook capable of rotatably clamping the chip box 204, and the other side is connected with the driving mechanism 203.
In this embodiment, the driving mechanism 203 drives the chip box 204 to pass by driving the clamping and limiting mechanism, so that the chip box 204 can be clamped for bidirectional transportation and can be accurately positioned at a required position. The front and rear sliders (2021, 2023) are connected through springs, and a rotating hook capable of rotatably clamping the chip box 204 is arranged on one side of the front and rear sliders (2021, 2023), so that the front and rear sliders (2021, 2023) can be driven to move by the spring force, and the rotating hook on the front and rear sliders (2021, 2023) is driven to rotate to clamp the chip box 204 without a gap, thereby improving the positioning accuracy of the chip box 204. In addition, the driving mechanism 203 can select a linear driving mechanism 203 such as a conveyor belt module and a screw motor module, so as to achieve the purpose of driving the chip box 204 to pass back and forth along a linear channel.
Based on the disclosure of the embodiment in fig. 1 or fig. 2, fig. 3 is a schematic structural diagram of an incubation tank assembly of a biochemical analyzer provided in a modified embodiment, and shows a station layout structure of the biochemical analyzer.
Referring to FIGS. 1 to 3, the one side of the incubation slot 205 is further provided with an in-place sensor for sensing positional information of the chip cartridge 204, and the in-place sensor may be disposed near an entrance of the chip cartridge 204 in the linear channel. One side of the incubation groove 205 is further provided with a chip cartridge identification site 2053, and the chip cartridge identification site 2053 is communicated with the linear channel. Wherein, the in-place sensor and the cartridge identification site 2053 may be disposed on the same side of the incubation well 205 as the puncturing site 2052 and the loading site 2051, or may be disposed on different sides of the incubation well 205 as the puncturing site 2052 and the loading site 2051.
The cartridge identification site 2053 may be located further from the inlet of the cartridge 204 of the linear channel than the puncturing site 2052 is located from the inlet of the cartridge 204 of the linear channel, or may be located closer to the inlet of the cartridge 204 of the linear channel than the puncturing site 2052 is located. The distance between the puncturing site 2052 and the inlet of the chip cartridge 204 of the linear channel may be longer than the distance between the loading site 2051 and the inlet of the chip cartridge 204 of the linear channel, or may be shorter than the distance between the loading site 2051 and the inlet of the chip cartridge 204 of the linear channel. Between the cartridge identification bit 2053 and the puncturing bit 2052, detection bits (2054, 2055) may be provided, the detection bits (2054, 2055) including a transmission detection bit 2054 and/or a scattering detection bit 2055, the transmission detection bit 2054 and/or the scattering detection bit 2055 may be provided side by side.
In a preferred embodiment, the position sensor, sample loading site 2051, puncturing site 2052, detection sites (2054, 2055), and cartridge identification site 2053 are located further from the inlet of the cartridge 204 in the linear channel, with reference to the inlet of the cartridge 204 in the linear channel.
It should be noted that the positioning sensor near the entrance of the chip box 204 in the linear channel can detect whether the chip box 204 is positioned at the first time, so as to trigger the further process. A transmission detection position 2054 and/or a scattering detection position 2055 are/is arranged between the cartridge identification position 2053 and the puncture position 2052, so that a light path can be established, and biochemical analysis of a sample can be realized. The cassette identification site 2053 is disposed on one side of the incubation slot 205 for identifying identification information (e.g., two-dimensional code) of the cassette 204 and confirming identity information of the cassette 204, thereby preventing errors of the test object.
The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.

Claims (10)

1. An incubator assembly for a biochemical analyzer, comprising: an incubation tank with a linear channel inside; a puncture position and a sample adding position which are communicated with the linear channel are arranged on the incubation groove at intervals along the direction of the linear channel; the side surface of the incubation groove is provided with a detection position communicated with the linear channel for biochemical detection; and one side of the linear channel is provided with a driving mechanism capable of driving the chip box internally sealed with the disposable test reagent to pass.
2. The incubator assembly of the biochemical analyzer according to claim 1, wherein the driving mechanism drives the cartridge to pass by driving a clamp stopper mechanism.
3. The incubation well assembly of biochemical analyzer according to claim 2, wherein the clamping and limiting mechanism comprises a limiting block and a front and a rear slide blocks connected by a spring; the limiting block limits the chip box; one side of the front and rear sliding blocks is provided with a rotary hook capable of rotatably clamping the chip box, and one side of the front and rear sliding blocks is connected with the driving mechanism.
4. The incubator assembly for a biochemical analyzer according to claim 1, wherein the incubator is in a strip configuration.
5. The incubator assembly for a biochemical analyzer according to claim 1, wherein one side of the incubator is further provided with an in-place sensor for sensing positional information of the chip cartridge.
6. The incubator assembly of the biochemical analyzer according to claim 5, wherein the in-place sensor is disposed near an entrance of the chip cartridge of the linear channel.
7. The incubator assembly of the biochemical analyzer of claim 1, wherein the lancing site is located further from the cassette inlet of the linear channel than the loading site is located from the cassette inlet of the linear channel.
8. The incubator assembly for a biochemical analyzer according to claim 7, wherein the incubator further has a cassette recognition site provided on one side thereof; the chip box identification position is communicated with the linear channel, and the distance between the chip box identification position and the linear channel is longer than the distance between the puncture position and the chip box inlet of the linear channel.
9. The incubator assembly of the biochemical analyzer according to claim 8, wherein the detection site is disposed between the cartridge identification site and the puncture site, and comprises a transmission detection site and/or a scattering detection site.
10. The biochemical analyzer of claim 1, comprising:
and the side wall of the chip box corresponding to the detection position is made of a light-transmitting material.
CN201920359928.7U 2019-03-21 2019-03-21 Incubation groove component of biochemical analyzer and biochemical analyzer Active CN209858594U (en)

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CN201920359928.7U CN209858594U (en) 2019-03-21 2019-03-21 Incubation groove component of biochemical analyzer and biochemical analyzer

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Application Number Priority Date Filing Date Title
CN201920359928.7U CN209858594U (en) 2019-03-21 2019-03-21 Incubation groove component of biochemical analyzer and biochemical analyzer

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112230005A (en) * 2020-01-17 2021-01-15 深圳市活水床旁诊断仪器有限公司 Physiological sample detection method and device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112230005A (en) * 2020-01-17 2021-01-15 深圳市活水床旁诊断仪器有限公司 Physiological sample detection method and device
CN112230005B (en) * 2020-01-17 2022-06-07 深圳市活水床旁诊断仪器有限公司 Physiological sample detection method and device

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