CN209848367U - Ursodeoxycholic acid concentration crystallizer - Google Patents
Ursodeoxycholic acid concentration crystallizer Download PDFInfo
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- CN209848367U CN209848367U CN201920476829.7U CN201920476829U CN209848367U CN 209848367 U CN209848367 U CN 209848367U CN 201920476829 U CN201920476829 U CN 201920476829U CN 209848367 U CN209848367 U CN 209848367U
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Abstract
The utility model discloses a ursodeoxycholic acid concentration crystallizing tank, in particular to the field of crystallizing tanks, which comprises a base, wherein a plurality of supporting rods are fixedly arranged at the top of the base, a concentration component is fixedly arranged at the top of each supporting rod, and a crystallizing component is fixedly arranged on each concentration component; the concentration assembly comprises a tank body, an air pipe penetrates through the top of the tank body, and a vacuum pump is fixedly arranged on the air pipe; the crystallization assembly comprises a fixed plate, and a hot air blower and an air cooler are fixedly arranged at the bottom of the fixed plate. The utility model discloses a vacuum pump makes jar body in atmospheric pressure reduce and makes enzyme liquid boiling point greatly reduced to cooperation air heater work makes enzyme liquid heat up through the heat transfer, makes the temperature not be higher than under the temperature of enzyme inactivation, just makes enzyme liquid boiling, thereby makes enzyme liquid rapid evaporation and concentrate, later through adding neutral salt saturated solution, and cooperation air-cooler makes enzyme liquid cooling crystallization with higher speed, whole concentrated crystallization efficiency is high, degree of automation is high, greatly reduced the cost of labor.
Description
Technical Field
The utility model relates to a crystallizer technical field, more specifically say, the utility model relates to a concentrated crystallizer of ursodeoxycholic acid.
Background
In the chemical process, after a hot saturated solution is cooled, a solute is precipitated in the form of crystals, the process is called crystallization, and concentration and crystallization are required in the production of the bear oxygen project enzyme.
In the crystallization of enzyme, the most commonly used method is salting-out crystallization, and the salting-out crystallization effect means that an electrolyte salting-out agent is added into a salt solution system, the added salting-out agent has stronger ion hydration action than other salts in the original solution, and the added salting-out agent reduces the number of free water molecules in the solution, thereby improving the effective concentration of a substance to be crystallized in the solution, and crystallizing and separating out the substance to be crystallized in the solution, namely the salting-out crystallization effect.
The crystallization tank for crystallization in the prior art has certain defects, such as concentration is needed before enzyme crystallization, enzyme inactivation is easy to realize high-temperature evaporation concentration, and the normal-temperature evaporation concentration efficiency is low, so that the crystallization efficiency is low, the concentration and crystallization cannot be integrally carried out, the automation degree is low, and the labor cost is increased.
SUMMERY OF THE UTILITY MODEL
The utility model overcomes the deficiencies in the prior art, the technical problem who solves is: the utility model provides a concentrated crystallizer of ursodeoxycholic acid, make jar internal atmospheric pressure reduce and make enzyme liquid boiling greatly reduced through the vacuum pump to work and make enzyme liquid heat up through the heat transfer with the air heater, make the temperature not be higher than under the temperature of enzyme deactivation, just make enzyme liquid boil, thereby make moisture rapid evaporation and concentration in the enzyme liquid, later through adding neutral salt saturated solution, and cooperate the air-cooler to make enzyme liquid cooling crystallization with higher speed, whole concentration crystallization efficiency is high, degree of automation is high, greatly reduced the cost of labor.
In order to solve the technical problem, the utility model discloses a technical scheme be: a ursodeoxycholic acid concentration crystallizing tank comprises a base, wherein a plurality of supporting rods are fixedly arranged at the top of the base, a concentration component is fixedly arranged at the top of each supporting rod, and a crystallizing component is fixedly arranged on each concentration component;
the concentration assembly comprises a tank body, an air pipe penetrates through the top of the tank body, and a vacuum pump is fixedly arranged on the air pipe;
the crystallization subassembly includes the fixed plate, fixed air heater and the air-cooler of being equipped with in fixed plate bottom, the fixed connecting pipe that is equipped with on the air heater, the air-cooler is fixed to be located on the connecting pipe, the fixed spiral pipe that is equipped with of connecting pipe one end, the spiral pipe runs through to locate on the jar body, the fixed neutral salt jar that is equipped with in jar body top, the fixed pipe that is equipped with on the neutral salt jar, pipe one end runs through to locate jar body top.
The fixed motor that is equipped with in fixed plate top, the fixed horizontal pole that is equipped with on the motor, cup joint on the horizontal pole and be equipped with the bearing, the bearing runs through and locates jar body one side.
Cup joint on the horizontal pole and be equipped with the spiral puddler, the internal portion of jar is located to the spiral puddler, the fixed discharge gate that is equipped with in jar body bottom.
The discharge gate one side is run through and is equipped with the filter cartridge, the fixed filter screen that is equipped with in filter cartridge bottom, filter cartridge one side is fixed and is equipped with the baffle.
The top of the tank body is provided with a feed hopper in a penetrating way, and a first valve is fixedly arranged on the feed hopper.
The guide pipe is fixedly provided with a second valve, the discharge port is fixedly provided with a third valve, and one side of the baffle is fixedly provided with a handle.
Compared with the prior art, the utility model following beneficial effect has: the vacuum pump is used for reducing the air pressure in the tank body to greatly reduce the boiling point of the enzyme liquid, the hot air blower is matched for working to heat the enzyme liquid through heat transfer, the enzyme liquid is boiled when the temperature is not higher than the enzyme inactivation temperature, so that the moisture in the enzyme liquid is quickly evaporated and concentrated, then the neutral salt saturated solution is added, and the air cooler is matched for cooling and accelerating crystallization of the enzyme liquid, so that the overall concentration and crystallization efficiency is high, the automation degree is high, and the labor cost is greatly reduced; the enzyme liquid in the tank body is stirred by the rotation of the spiral stirring rod, so that the enzyme liquid is stirred, and the evaporation, concentration and crystallization of the enzyme liquid are further accelerated; the filter screen through setting up filters the enzyme crystallization and crosses, later through the pulling handle, drives baffle on it and the filter cartridge on the baffle and deviate from the discharge gate, and the convenient enzyme crystallization that will filter out takes out, has made things convenient for the collection of enzyme crystallization.
Drawings
The present invention will be described in further detail with reference to the accompanying drawings.
Fig. 1 is a schematic view of the overall structure of the present invention.
Fig. 2 is a schematic view of the bottom structure of the tank of the present invention.
Fig. 3 is a schematic view of the structure of the base of the present invention.
Fig. 4 is a schematic view of the filter cassette of the present invention.
Fig. 5 is a schematic view of the three-dimensional structure of the filter cartridge of the present invention.
In the figure: the device comprises a base 1, a support rod 2, a concentration component 3, a crystallization component 4, a tank 5, an air pipe 6, a vacuum pump 7, a fixing plate 8, a hot air blower 9, a cold air blower 10, a connecting pipe 11, a spiral pipe 12, a neutral salt tank 13, a guide pipe 14, a motor 15, a cross rod 16, a bearing 17, a spiral stirring rod 18, a discharge port 19, a filter box 20, a filter screen 21, a baffle 22, a feed hopper 23, a first valve 24, a second valve 25, a third valve 26 and a handle 27.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention; based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
The utility model provides a ursodeoxycholic acid concentration crystallizing tank as shown in figures 1-5, which comprises a base, wherein a plurality of support rods are fixedly arranged at the top of the base, a concentration component is fixedly arranged at the top of each support rod, and a crystallizing component is fixedly arranged on each concentration component;
the concentration assembly comprises a tank body, an air pipe penetrates through the top of the tank body, and a vacuum pump is fixedly arranged on the air pipe;
the crystallization subassembly includes the fixed plate, fixed air heater and the air-cooler of being equipped with in fixed plate bottom, the fixed connecting pipe that is equipped with on the air heater, the air-cooler is fixed to be located on the connecting pipe, the fixed spiral pipe that is equipped with of connecting pipe one end, the spiral pipe runs through to locate on the jar body, the fixed neutral salt jar that is equipped with in jar body top, the fixed pipe that is equipped with on the neutral salt jar, pipe one end runs through to locate jar body top.
The fixed motor that is equipped with in fixed plate top, the fixed horizontal pole that is equipped with on the motor, cup joint on the horizontal pole and be equipped with the bearing, the bearing runs through and locates jar body one side.
Cup joint on the horizontal pole and be equipped with the spiral puddler, the internal portion of jar is located to the spiral puddler, the fixed discharge gate that is equipped with in jar body bottom.
The discharge gate one side is run through and is equipped with the filter cartridge, the fixed filter screen that is equipped with in filter cartridge bottom, filter cartridge one side is fixed and is equipped with the baffle.
The top of the tank body is provided with a feed hopper in a penetrating way, and a first valve is fixedly arranged on the feed hopper.
The guide pipe is fixedly provided with a second valve, the discharge port is fixedly provided with a third valve, and one side of the baffle is fixedly provided with a handle.
The utility model discloses the theory of operation: referring to the attached drawings 1-5 of the specification, in operation, after a first valve 24 is opened, enzyme liquid is added into a feed hopper 23, the enzyme liquid enters a tank body 5 through the feed hopper 23, then the valve is closed, a vacuum pump 7 is enabled to work to pump air from the tank body 5 to the outside of the tank body 5 through an air pipe 6, the tank body 5 is gradually close to a vacuum state, a hot air blower 9 works to generate hot air, the hot air is blown into a spiral pipe 12 through a connecting pipe 11, the enzyme liquid is enabled to obtain heat of the hot air in the spiral pipe 12 through heat transfer due to the fact that the enzyme liquid is in contact with the outside of the spiral pipe 12, the temperature is raised to a proper temperature which does not enable the enzyme to be inactivated, due to the fact that the tank body 5 is close to vacuum, the atmospheric pressure is extremely low, the boiling point is close to normal temperature, the enzyme liquid is heated to a certain temperature, moisture in, the utility model discloses a vacuum pump 7 makes atmospheric pressure in the jar body 5 reduce and make the boiling point of enzyme liquid greatly reduce, and cooperates with hot-blast blower 9 work to make the enzyme liquid heat up through the heat transfer, makes the temperature be not higher than the temperature of enzyme inactivation, just makes the enzyme liquid boil, thereby makes moisture in the enzyme liquid evaporate fast and concentrate, afterwards makes the enzyme liquid cool down and accelerate the crystallization through adding neutral salt saturated solution, and cooperates with air-cooler 10 to make the enzyme liquid, and whole concentration crystallization efficiency is high, and degree of automation is high, has greatly reduced the cost of labor; the motor 15 works to drive the cross rod 16 on the tank body to rotate, the cross rod 16 rotates to drive the spiral stirring rod 18 on the cross rod to rotate, and the spiral stirring rod 18 rotates to stir the enzyme liquid in the tank body 5, so that the enzyme liquid turns over, and the evaporation concentration and crystallization of the enzyme liquid are further accelerated; through opening third valve 26 after the crystallization is accomplished, make enzyme liquid and neutral salt mixed solution flow out from discharge gate 19, filter screen 21 through setting up when flowing out filters out the enzyme crystallization, later through pulling handle 27, drives baffle 22 and the filter cartridge 20 on the baffle 22 above that and deviate from discharge gate 19, conveniently takes out the enzyme crystallization that filters out, has made things convenient for the collection of enzyme crystallization.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; although the present invention has been described in detail with reference to the foregoing embodiments, it should be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; such modifications and substitutions do not depart from the spirit and scope of the present invention.
Claims (6)
1. The utility model provides a concentrated crystallizer of ursodeoxycholic acid, includes base (1), its characterized in that: a plurality of support rods (2) are fixedly arranged at the top of the base (1), a concentration component (3) is fixed at the top of each support rod (2), and a crystallization component (4) is fixedly arranged on each concentration component (3);
the concentration component (3) comprises a tank body (5), an air pipe (6) penetrates through the top of the tank body (5), and a vacuum pump (7) is fixedly arranged on the air pipe (6);
crystallization unit (4) are including fixed plate (8), fixed plate (8) bottom is fixed and is equipped with air heater (9) and air-cooler (10), the fixed connecting pipe (11) that is equipped with on air heater (9), air-cooler (10) are fixed to be located on connecting pipe (11), connecting pipe (11) one end is fixed and is equipped with spiral pipe (12), spiral pipe (12) run through locate on jar body (5), jar body (5) top is fixed and is equipped with neutral salt jar (13), the fixed pipe (14) that is equipped with on neutral salt jar (13), pipe (14) one end runs through and locates jar body (5) top.
2. The ursodeoxycholic acid concentration crystallizing tank of claim 1, characterized in that: fixed plate (8) top is fixed and is equipped with motor (15), fixed horizontal pole (16) that are equipped with on motor (15), it is equipped with bearing (17) to cup joint on horizontal pole (16), bearing (17) run through and locate jar body (5) one side.
3. The ursodeoxycholic acid concentration crystallizing tank of claim 2, characterized in that: the spiral stirring rod (18) is sleeved on the cross rod (16), the spiral stirring rod (18) is arranged inside the tank body (5), and a discharge hole (19) is fixedly formed in the bottom of the tank body (5).
4. The ursodeoxycholic acid concentration crystallization tank according to claim 3, characterized in that: discharge gate (19) one side is run through and is equipped with filter cartridge (20), filter cartridge (20) bottom is fixed and is equipped with filter screen (21), filter cartridge (20) one side is fixed and is equipped with baffle (22).
5. The ursodeoxycholic acid concentration crystallizing tank of claim 1, characterized in that: the top of the tank body (5) is provided with a feed hopper (23) in a penetrating way, and the feed hopper (23) is fixedly provided with a first valve (24).
6. The ursodeoxycholic acid concentration crystallization tank according to claim 4, characterized in that: the guide pipe (14) is fixedly provided with a second valve (25), the discharge hole (19) is fixedly provided with a third valve (26), and one side of the baffle plate (22) is fixedly provided with a handle (27).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920476829.7U CN209848367U (en) | 2019-04-10 | 2019-04-10 | Ursodeoxycholic acid concentration crystallizer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201920476829.7U CN209848367U (en) | 2019-04-10 | 2019-04-10 | Ursodeoxycholic acid concentration crystallizer |
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| Publication Number | Publication Date |
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| CN209848367U true CN209848367U (en) | 2019-12-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201920476829.7U Active CN209848367U (en) | 2019-04-10 | 2019-04-10 | Ursodeoxycholic acid concentration crystallizer |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113005004A (en) * | 2020-06-06 | 2021-06-22 | 刘桂玲 | Bio-enzyme concentration device with large coating area |
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2019
- 2019-04-10 CN CN201920476829.7U patent/CN209848367U/en active Active
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113005004A (en) * | 2020-06-06 | 2021-06-22 | 刘桂玲 | Bio-enzyme concentration device with large coating area |
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