CN209847954U - External life support control device - Google Patents
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- CN209847954U CN209847954U CN201820944537.7U CN201820944537U CN209847954U CN 209847954 U CN209847954 U CN 209847954U CN 201820944537 U CN201820944537 U CN 201820944537U CN 209847954 U CN209847954 U CN 209847954U
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Abstract
The utility model discloses an external life supports controlling means, controlling means include ECMO control system, blood gas analyzer, biochemical analysis appearance, ACT detector, empty oxygen blender, syringe pump, and ECMO control system is connected respectively with each instrument. The utility model provides the high intelligence of ECMO equipment lets it can follow the patient condition in the aspect of some treatment means and carry out automatic adjustment. The timely response capability of the system to the change of the patient condition is improved. The utility model discloses a 2 take the regulation of button function can adjust the target value more meticulously, avoided changing the rotational speed because of rocking with the maloperation.
Description
Technical Field
The utility model relates to the field of health equipment, in particular to an external life support control device.
Background
The existing ECMO (membrane lung oxygenation) equipment for supporting in vitro life completely depends on import, a control system of the existing ECMO equipment abroad mainly controls the rotating speed of a motor, the rotating speed of an impeller in a blood pump is controlled through magnetic coupling, the rotating speed is adjusted through a potentiometer type knob, a limit switch is generally arranged at the position of 2000 revolutions, when the rotating speed is adjusted downwards from more than 2000 revolutions, the limit switch is adjusted to 2000 revolutions for limiting protection, the rotating speed lower than 2000 can be set only by pressing the limit switch, the existing ECMO equipment control mode at abroad has two modes of flow control (LPM) and rotating speed control (RPM), only one rotating speed adjusting knob is used, and no flow adjusting knob is used. The sensor of ECMO can detect flow, pressure, temperature and blood oxygen saturation, and these parameters detected are displayed through the screen, and alarm reminding is carried out when relevant signals are found to exceed the set range. Physicians need to observe these data regularly and to combine blood gas analysis and biochemical analysis to assess the current condition of the patient.
The control of the blood temperature is realized by adding an independent variable temperature water tank, and the detection, regulation and control of the temperature and the water circulation control of the water tank are all positioned in the water tank.
At present, the following problems exist in the prior art: the patient is treated by the ECMO for several days or even weeks, the physical condition of the patient can change at any time, but a doctor cannot always monitor one patient, only can observe and check the patient regularly, cannot adjust and treat the patient according to the condition of the patient in real time, and the time-dependent delay can possibly cause the condition of the patient to deteriorate.
When the ECMO device is used for outdoor first aid, equipment such as a monitor and the like needs to be carried at the same time, portability is not facilitated, and the function integration level is not high.
The control of the blood temperature is not integrated in the ECMO host, the use and the operation are inconvenient, the external temperature-changing water tank improves the system cost, and the system portability is reduced.
The blood flow, the blood pump rotating speed and the blood temperature can not be adjusted through one interface, and the adjusting knob adopting the potentiometer mode easily changes set values due to shaking and mistaken touch.
In addition, in the prior art, the target flow rate cannot be adjusted quickly in the flow rate control mode. The rotation speed adjusting knob may affect the change of the rotation speed setting parameter when the rotation speed adjusting knob is severely shaken or in other unexpected situations.
SUMMERY OF THE UTILITY MODEL
To solve the above technical problems, an object of the present invention is to provide an in vitro life support control device.
In order to achieve the above object, the present invention is realized according to the following technical solution:
the utility model provides an external life supports controlling means, its characterized in that contains ECMO control system, blood gas analysis appearance, biochemical analysis appearance, ACT detector, air oxygen mixer, syringe pump, wherein, blood gas analysis appearance, biochemical analysis appearance, ACT detector, air oxygen mixer, syringe pump respectively in the ECMO system is connected, blood gas analysis appearance automatic acquisition blood gas detection data, biochemical detection data is obtained automatically to the biochemical analysis appearance, ECMO system obtains can be according to setting for the situation control after the clotting time from the ACT detector the syringe pump is automatic to be added heparin and platelet, and the blood gas detection data that obtains according to blood gas analysis appearance and automatic control the air oxygen mixer carries out oxygen concentration and gas flow and adjusts.
In the technical scheme, the ECMO control system comprises a temperature control unit circuit, an acousto-optic warning circuit, a wireless communication interface, a brushless direct current motor driving circuit, an MCU main control unit circuit, a power supply unit circuit, a display screen interface circuit, a keypad communication interface, an RS232 interface, flow, pressure, temperature and blood oxygen sensor interface, wherein the MCU main control unit circuit adopts a main control chip of an ARM core, the temperature control unit circuit comprises a temperature sensor, a signal conditioning circuit and an MOS tube H-bridge driving circuit, the MCU main control unit circuit collects the temperature of water in a water tank through the temperature sensor, outputs PWM signals to control the opening and closing of 4 MOS tubes in the H-bridge driving circuit after the control mode is selected to operate, the MCU main control unit circuit controls the enabling of the brushless direct current motor driving circuit through a common IO port and receives speed signals fed back by the motor, the MCU main control unit circuit controls the rotating speed of the motor through a PWM output IO port, and is connected with the wireless interface circuit, the display screen interface circuit, the keypad communication interface, the flow, pressure, temperature and blood oxygen sensor interface circuit through serial ports;
wherein, the temperature sensor adopts PT1000, directly contacts with the object to be measured, the resistance value of the temperature sensor PT1000 changing with the temperature is converted into a voltage value through a constant voltage source and a high-precision resistor, the voltage value enters an AD conversion interface of the MCU after being amplified by AD623, the voltage value of an analog quantity is converted into a digital quantity, a control program reversely deduces a temperature value according to the digital quantity detected by the temperature, the control ends of 4 MOS tubes in the MOS tube H-bridge driving circuit are connected to 4 PWM output interfaces of the MCU, the MCU controls the positive and negative polarities and the voltage value of the voltage output by the MOS tube H-bridge driving circuit by changing the duty ratio and the polarity of the PWM, the output of the semiconductor refrigerating sheet is connected with a semiconductor refrigerating sheet, one surface of the semiconductor refrigerating sheet is tightly attached to the water tank, the other surface of the semiconductor refrigerating sheet is attached to the radiator, the polarity of output voltage is controlled to change the semiconductor to heat or refrigerate the water tank, and the duty ratio of PWM is controlled to control the temperature to stabilize the water tank;
the brushless direct current motor driving circuit adopts a special motor control chip A4931, an enable signal control chip A4931 outputs PWM, the enabled chip A4931 generates PWM signals to control 6 MOS (metal oxide semiconductor) tubes according to direction signals and pulse width signals received from an MCU (micro control unit), and outputs three-phase voltage signals to control the direction and the rotating speed of the motor; differential signals of the three-phase encoder are converted into TTL signals through AM26LV31 and fed back to A4931 to provide speed feedback, and speed pulse signals output by the chip A4931 are sent to the MCU to detect the running speed of the motor;
the flow sensor interface circuit adopts an RS485 interface, and the pressure sensor interface circuit and the blood oxygen sensor interface circuit respectively adopt serial TTL interfaces;
the power supply unit circuit converts the input DC24V into DC12V, DC5V and DC DC3.3V voltages to supply power to each unit module;
the wireless communication interface adopts a ZIGBEE module and a WIFI module, the ZIGBEE module is wirelessly connected with the blood gas analyzer, the biochemical analyzer, the ACT detector, the air-oxygen mixer and the injection pump, and the WIFI module is connected with the Internet;
the acousto-optic warning circuit is realized by a buzzer and an indicator light, and when an abnormal condition occurs, the buzzer is started to sound and the indicator light displays different colors to warn.
In the technical scheme, the MCU main control unit circuit adopts an STM32f7 series chip, the chip provides 8 serial ports, the running main frequency speed reaches 216MHZ, and the requirements of a plurality of serial ports and the running speed are met.
In the technical scheme, the control device is further provided with 2 pulse type knobs and 6 key switches, wherein one knob is used for coarse adjustment, the other knob is used for fine adjustment, the knobs and the key switches are combined to set mode switching, target blood temperature, target rotating speed and target flow, a target set value is adjusted according to signals of the keys and the knobs, and the signals are displayed on a display screen.
In the technical scheme, the knob is a coding type knob, two paths of square waves with a 90-degree difference are generated during rotation, the square waves generated by forward rotation and reverse rotation are opposite in phase sequence, the knob has a key function, and the knob is pressed down to confirm the set value after each adjustment.
Compared with the prior art, the utility model, following beneficial effect has:
1. the utility model discloses an equipment passes through the connection of equipment such as hardware communication interface and blood gas, biochemical analyzer, ACT blood coagulation time detector, air-oxygen mixer and syringe pump, acquires the more important blood gas biochemical parameters among the ECMO treatment process to flow and oxygen concentration to this automatic air-oxygen mixer control, the automatic injection medicine. The control method improves the intelligence of the ECMO equipment, and enables the ECMO equipment to be automatically adjusted according to the condition of a patient in terms of certain treatment measures. The timely response capability of the system to the change of the patient condition is improved.
2. The target rotating speed, the target blood temperature and the target blood flow of the system can be adjusted and set on the same interface, the target value can be adjusted more finely by adjusting 2 keys, and the rotating speed change caused by shaking and misoperation is avoided.
3. The system integrates the functions of human arterial oxygen saturation detection, heart rate monitoring and blood temperature control, and can be carried without a monitor and a single variable-temperature water tank during outdoor first aid, so that the portability and the maneuverability of the system are improved.
4. Realizes the localization of the in vitro life support system and greatly reduces the cost.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic diagram illustrating the connection between the ECMO system and the peripheral device according to the present invention;
fig. 2 is a schematic structural diagram of the ECMO control system of the present invention;
fig. 3 is a schematic circuit diagram of the ECMO system host according to the present invention;
fig. 4 is a schematic circuit diagram of the ECMO system of the present invention;
fig. 5 is a circuit of the temperature control unit of the present invention;
fig. 6 shows a circuit of the driving unit of the brushless dc motor of the present invention;
FIG. 7 is a schematic diagram of the RS232 and pressure, flow and blood oxygen sensor interface circuit of the present invention;
fig. 8 is a schematic circuit diagram of the power supply unit of the present invention;
FIG. 9 is a schematic diagram of the MCU master control unit circuit of the present invention;
fig. 10 is a schematic diagram of a switch structure of the ECMO apparatus of the present invention;
fig. 11 is a schematic diagram of a control method of the ECMO system of the present invention;
fig. 12 is a schematic diagram of the LPM control mode of the present invention;
fig. 13 is a schematic diagram of the RPM control mode of the present invention;
fig. 14 is a schematic view of the blood temperature control mode of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention.
Fig. 1 is a schematic diagram illustrating the connection between the ECMO system and the peripheral device according to the present invention; as shown in fig. 1, the utility model discloses in vitro life support system gathers the blood flow in the ECMO circulation pipeline in real time through multi-functional integrated circuit, blood temperature, membrane lung fore-and-aft pressure, the pressure of vein drainage end, venous blood oxygen saturation, the terminal arterial blood oxygen saturation of patient's limbs, multiple parameters such as hematocrit, rhythm of the heart and bubble detection in the circulation pipeline. Meanwhile, the system is provided with 232 or wireless interfaces which can be connected with instruments and equipment such as a blood gas analyzer, a biochemical analyzer, an injection pump, an air-oxygen mixer, a monitor and the like, and can automatically acquire detection data of blood gas, biochemistry and the like, the ECMO system can control the injection pump to automatically add heparin and platelets according to set conditions after acquiring blood coagulation time from the ACT instrument, and automatically control the air-oxygen mixer to adjust oxygen concentration and gas flow according to blood gas parameters acquired by the blood gas analyzer. The control and control method improves the intelligence of the ECMO equipment, and enables the ECMO equipment to be automatically adjusted according to the patient condition in terms of certain treatment measures. The timely response capability of the system to the change of the patient condition is improved.
Wherein, the utility model discloses a blood gas analyzer means utilizes the electrode to carry out the instrument of survey to relevant index such as pH valve (pH), carbon dioxide partial pressure (PCO2) and oxygen partial pressure (PO2) in the artery in the short time, for prior art in this field, no longer gives unnecessary details here, the utility model discloses a focus does not lie in improving blood gas analyzer's structure.
Biochemical analyzers, also commonly referred to as biochemics, are instruments that measure a specific chemical component in body fluids using the principle of photoelectric colorimetry, and are common devices for medical diagnosis, mainly used for measuring a specific chemical component in body fluids. The biochemical analyzer is the prior art in the field, and is not described herein in detail, and the structure thereof is not the innovation point of the present invention.
An ACT (Activated Clotting Time of whole blood) monitor is a calibration index for testing Clotting Time when being applied to extracorporeal circulation of cardiac surgery at home and abroad, is an important measure for preventing postoperative bleeding, heparin is extracted from livers and lungs of animals, can inhibit thromboplastin, thrombin and the like, is commonly used for preventing thrombus formed by chronic nephritis hemodialysis and treating diseases such as cerebral thrombosis and the like in clinic except extracorporeal circulation, and can be used for guiding reasonable use of the heparin and protamine by carrying out identification and measurement on ACT values. ACT monitors are known in the art and will not be described further herein.
The medical air-oxygen mixer is an oxygen supply device, which can freely adjust the oxygen concentration of the input medical air and medical oxygen according to the volume ratio so as to prevent the patient from generating oxygen concentration complication due to overhigh oxygen concentration or generating insufficient oxygen supply due to overlow oxygen concentration, thereby providing a safe and reasonable oxygen supply environment for the patient. The medical air-oxygen mixer is also a key part of medical equipment such as a breathing machine, a CPAP (continuous positive airway pressure), an anesthesia machine and the like, is necessary equipment of a hospital, and the performance judgment of the medical air-oxygen mixer directly depends on the accuracy of the oxygen concentration of output gas. The air-oxygen mixer is a prior art in the field and is not described in detail herein.
The utility model discloses an ECMO device host computer for external life support except possessing flow, rotational speed detection and control function, pressure detection function, bubble detection, venous blood oxygen saturation monitoring function, packed red blood cell detection function, blood temperature detection function, emergency detection and the warning on the foreign ECMO equipment still integrated the temperature detection and the control of water tank, hydrologic cycle to and the arterial blood oxygen saturation and the rhythm of the heart monitoring function of human tissue tip.
The structure of the ECMO control system is shown in fig. 2, in which an external AC220V power is converted into a DC24V through a power adapter, and the DC24V is connected to a power board through a connector to supply power to the whole system and charge a battery, the power board converts the DC24v into a DC12V, a DC5V and DC3.3V to supply power to each functional module circuit, and simultaneously performs charging management on the battery, and the power board communicates with the main control board through an RS232 serial port to provide a power status signal to the main control board. The control circuit of the variable temperature water tank is integrated on the main control board, and the main control board is electrically connected with the heating plate, the water pump and the temperature sensor in the variable temperature water tank through the connector so as to control the temperature of the water tank and drive the water pump. The driving circuit of the brushless direct current motor is integrated on the main control board, and the main control board is electrically connected with a power line and a Hall sensor of the brushless direct current motor through a connector so as to control the rotating speed of the brushless direct current motor. The knob and the key board are communicated with the main control board through an RS232 serial port, and the knob and the key operation state are provided for the main control board. The main control board is in data communication with the flow and bubble detection sensors through the RS485 interface so as to acquire flow information and bubble detection information in real time. The main control board is connected with the display screen, the wireless module, the temperature sensor, the blood oxygen sensor and the pressure sensor through serial ports to obtain corresponding data.
The ECMO control system comprises a temperature control unit circuit, an acousto-optic warning circuit, a wireless communication interface, a brushless direct current motor driving circuit, an MCU main control unit circuit, a power supply unit circuit, a display screen interface circuit, a key board communication interface, an RS232 interface, a flow, a pressure, a temperature and a blood oxygen sensor interface, wherein the MCU main control unit circuit adopts a main control chip of an ARM core, the temperature control unit circuit comprises a temperature sensor, a signal conditioning circuit and an MOS tube H-bridge driving circuit, the MCU main control unit circuit collects the temperature of water in a water tank through the temperature sensor, outputs PWM signals to control the opening and closing of 4 MOS tubes in the H-bridge driving circuit after selecting a control mode to operate, controls the enabling of the brushless direct current motor driving circuit through a common IO port, and receives speed signals fed back by the motor, the MCU main control unit circuit controls the rotating speed of the motor through a PWM output IO port, and is connected with the wireless interface circuit, the display screen interface circuit, the keypad communication interface, the flow, pressure, temperature and blood oxygen sensor interface circuit through serial ports;
the schematic diagram of the H-bridge driving circuit is shown in FIG. 4: the MCU main control unit collects the temperature of the water tank, the PWM signals are output to control the opening and closing of 4 MOS tubes in the H bridge after the operation of a control algorithm, the opening and closing of the MOS tubes control the connection and disconnection of a power supply of the semiconductor refrigeration piece in a fixed time period, in the connection and disconnection time period, the change of the power supply connection time controls the temperature of water in the water tank to reach a set target temperature and be constant, the precision is kept within plus or minus 0.5 ℃, the H bridge circuit can control the polarity of output voltage, and the change of the polarity can control the conversion between the heating effect and the refrigeration effect of the semiconductor refrigeration piece.
The wireless communication interface adopts a ZIGBEE module and a WIFI module, the ZIGBEE module can be wirelessly connected with a blood gas analyzer, a biochemical analyzer, an ACT detector, an air-oxygen mixer and an injection pump, and the WIFI module is connected with the Internet;
the acousto-optic warning circuit is realized by a buzzer and an indicator light, and when an abnormal condition occurs, the buzzer is started to sound and the indicator light displays different colors to warn.
FIG. 5 is a schematic diagram of a temperature control unit circuit of the present invention, in which a temperature sensor employs a PT1000 directly contacting with an object to be tested, the temperature sensor PT1000 is converted into a voltage value along with a temperature variation resistance value by a constant voltage source and a high precision resistor, the voltage value is amplified by an AD623 and then enters an AD conversion interface of an MCU to convert an analog voltage value into a digital value, a control program reversely deduces a temperature value according to the digital value detected by the temperature, control terminals of 4 MOS transistors in an MOS transistor H-bridge driving circuit are connected to 4 PWM output interfaces of the MCU, the MCU controls positive and negative polarities and a voltage value of a voltage output by the MOS transistor H-bridge driving circuit by changing the duty ratio and polarity of the PWM, the output is connected to a semiconductor refrigeration chip, one side of the semiconductor refrigeration chip is attached to a water tank, the other side of the semiconductor refrigeration chip is attached to a radiator, the polarity of the control output voltage, the temperature is controlled to stabilize by controlling the duty cycle of the PWM.
Fig. 6 is a circuit of the driving unit of the brushless dc motor of the present invention, wherein the driving circuit of the brushless dc motor adopts a dedicated motor control chip a4931, the enable signal control chip a4931 outputs PWM, the enable chip a4931 generates PWM signal to control 6 MOS transistors according to the direction signal and the pulse width signal received from the MCU, and outputs three-phase voltage signal to control the direction and the rotation speed of the motor; the differential signal of the three-phase encoder is converted into a TTL signal through AM26LV31 and fed back to a4931, so as to provide speed feedback, and the speed pulse signal output by the chip a4931 is sent to the MCU to detect the running speed of the motor.
FIG. 7 is a schematic view of the connection of the communication interface of the present invention with a pressure, flow, blood oxygen sensor, a biochemical, blood gas, ACT detector, an injection pump, and an air-oxygen mixer; the flow sensor interface is an RS485 interface, and the pressure sensor and the blood oxygen sensor interface are 2 serial TTL interfaces. The interfaces of the biochemical detector, the blood gas detector, the ACT detector and the air-oxygen mixer are RS232 interfaces, and the interface of the injection pump is a wireless communication interface.
Fig. 8 is a schematic diagram of a power supply unit circuit according to the present invention, wherein the power supply unit circuit converts the input DC24V into DC12V, DC5V, DC3.3V voltage to supply power to each unit module.
Fig. 9 is the utility model discloses a MCU master control unit circuit schematic, master control MCU adopt STM32f7 series chip, and 8 serial ports, 1 USB interface and input/output IO mouth are drawn forth to main MCU. The peripheral part is provided with 1 external memory and 1 hardware watchdog circuit, the MCU operation main frequency speed can reach 216MHZ, and the requirements of a plurality of serial ports of the system and the operation speed are met.
The ECMO device is provided with 2 pulsed knobs, one for coarse adjustment and 6 push-button switches, the other for fine adjustment. As shown in the following figure, the mode button can be switched between LPM and RPM modes, and the target rotation speed and the target flow rate value can be adjusted according to the current mode after the flow button is pressed. The target temperature setting can be performed after the temperature key is pressed.
The change in value is greater for each angle of rotation of the coarse adjustment knob than for the fine adjustment. The knob is a coding type knob, two paths of square waves with a 90-degree difference are generated during rotation, the square waves generated by forward rotation and reverse rotation are opposite in phase sequence, the knob has a key function, and a set value is confirmed by pressing the knob after each adjustment. The phenomena of misoperation and parameter setting change caused by vibration are avoided.
The main controller performs constant-current or constant-speed control on the motor by flow feedback or rotating speed feedback, and performs constant-temperature control on the water tank. The main controller software flow is shown in the following figure. And controlling the blood flow, the motor rotating speed and the blood temperature by adopting a PID algorithm, controlling the dosage and the speed of heparin injection by the injection pump according to an ACT measurement result, and regulating the gas flow and the oxygen concentration of the air-oxygen mixer according to blood gas analysis. The flow sensor integrates a bubble detection function, and when the system detects that bubbles exceed a set size, the system performs sound-light alarm. The main control system monitors the artery and vein pressure, flow and blood oxygen saturation in real time, and gives an alarm when any parameter exceeds a set range.
The combination of the knob and the key can set the target flow, the target rotating speed and the target blood temperature, and the system adjusts the target set value according to the key and the knob signal and simultaneously displays the target set value on the display screen. When the new set value is determined, the control quantity is calculated in real time according to a PID algorithm and is output to the control module to control the rotating speed of the motor and the blood temperature.
LPM control algorithm (flow control mode):
in the LPM control method, as shown in fig. 12, the main controller calculates a body surface area BSA based on an algorithm of the inputted height, weight and body surface area, calculates a target blood flow rate based on the body surface area and the heart index, and sets the calculated target blood flow rate as a control target flow rate in the LPM control mode. The main controller monitors the flow value in real time after receiving the starting operation instruction, and performs PID algorithm operation on the target flow and the real-time flow to obtain a current motor speed control signal, and the signal controls the rotating speed of the motor through the brushless direct current motor driving module so as to control the blood flow circulating in the system. And gradually accelerating and decelerating by an acceleration and deceleration algorithm in the process of starting to reach the target flow. Constant blood flow control is performed after the target flow is reached. Keeping the flow variation range within plus or minus 5 percent. And when the monitored flow value exceeds the set protection range, performing sound-light alarm prompting.
RPM control algorithm (speed control mode):
in the RPM control method, as shown in fig. 13, the main controller sets the input target rotation speed as a control target. After receiving the starting operation instruction, the main controller monitors the rotating speed value in real time, and performs PID algorithm operation on the target rotating speed and the real-time rotating speed to obtain a current motor speed control signal, wherein the signal controls the rotating speed of the motor through the brushless direct current motor driving module so as to control the blood flow circulating in the system. And gradually accelerating and decelerating by an acceleration and deceleration algorithm in the process of starting to reach the target rotating speed. And performing constant motor rotation speed control after the target rotation speed is reached. Keeping the variation range of the rotating speed within plus or minus 2 percent. And when the monitored rotating speed value exceeds the set protection range, performing sound-light alarm prompting.
Blood temperature control algorithm:
as shown in fig. 14, the main controller sets the input target blood temperature as the control target. The main controller monitors the blood temperature in real time after receiving the starting operation instruction, and performs PID algorithm and fuzzy algorithm combined operation on the target temperature and the real-time temperature to obtain a current temperature control module control signal, and the signal controls the blood temperature circulating in the system through the heating or instruction power output by the temperature control circuit. Full speed ramping up or down occurs during start-up to the target speed. Constant temperature control is performed after the target temperature is reached. The temperature variation range is kept within plus or minus 0.5 degrees. And when the monitored temperature value exceeds the set protection range, performing sound-light alarm prompting.
One skilled in the art will appreciate that, in addition to implementing the system and its various devices, modules, units provided by the present invention as pure computer readable program code, the system and its various devices, modules, units provided by the present invention can be implemented with the same program in the form of logic gates, switches, application specific integrated circuits, programmable logic controllers, embedded microcontrollers and the like, all by logically programming the method steps. Therefore, the system and the devices, modules and units thereof provided by the present invention can be regarded as a hardware component, and the devices, modules and units included therein for implementing various programs can also be regarded as structures in the hardware component; means, modules, units for realizing various functions can also be regarded as structures within both software programs and hardware components for realizing the methods.
The foregoing description of the specific embodiments of the invention has been presented. It is to be understood that the present invention is not limited to the specific embodiments described above, and that various changes or modifications may be made by those skilled in the art within the scope of the appended claims without departing from the spirit of the invention. The embodiments and features of the embodiments of the present application may be combined with each other arbitrarily without conflict.
Claims (4)
1. An in vitro life support control device is characterized by comprising an ECMO control system, a blood gas analyzer, a biochemical analyzer, an ACT detector, an air-oxygen mixer and an injection pump, wherein the blood gas analyzer, the biochemical analyzer, the ACT detector, the air-oxygen mixer and the injection pump are respectively connected with the ECMO system, the blood gas analyzer automatically acquires blood gas detection data, the biochemical analyzer automatically acquires biochemical detection data, the ECMO system controls the injection pump to automatically add heparin and platelets according to a set condition after acquiring blood coagulation time from the ACT detector, and the air-oxygen mixer is automatically controlled to adjust oxygen concentration and gas flow according to the blood gas detection data acquired by the blood gas analyzer;
the ECMO control system comprises a temperature control unit circuit, an acousto-optic warning circuit, a wireless communication interface, a brushless direct current motor driving circuit, an MCU main control unit circuit, a power supply unit circuit, a display screen interface circuit, a key board communication interface, an RS232 interface, a flow, pressure, temperature and blood oxygen sensor interface, wherein the MCU main control unit circuit adopts a main control chip of an ARM core, the temperature control unit circuit comprises a temperature sensor, a signal conditioning circuit and an MOS tube H-bridge driving circuit, the MCU main control unit circuit collects the temperature of water in a water tank through the temperature sensor, outputs PWM signals to control the opening and closing of 4 MOS tubes in the H-bridge driving circuit after selecting a control mode to operate, controls the enabling of the brushless direct current motor driving circuit through a common IO port, receives speed signals fed back by a motor, and controls the rotating speed of the motor through a PWM IO port, the MCU main control unit circuit is connected with the wireless interface circuit, the display screen interface circuit, the key board communication interface, the flow sensor interface circuit, the pressure sensor interface circuit, the temperature sensor interface circuit and the blood oxygen sensor interface circuit through serial ports;
wherein, the temperature sensor adopts PT1000, directly contacts with the object to be measured, the resistance value of the temperature sensor PT1000 changing with the temperature is converted into a voltage value through a constant voltage source and a high-precision resistor, the voltage value enters an AD conversion interface of the MCU after being amplified by AD623, the voltage value of an analog quantity is converted into a digital quantity, a control program reversely deduces a temperature value according to the digital quantity detected by the temperature, the control ends of 4 MOS tubes in the MOS tube H-bridge driving circuit are connected to 4 PWM output interfaces of the MCU, the MCU controls the positive and negative polarities and the voltage value of the voltage output by the MOS tube H-bridge driving circuit by changing the duty ratio and the polarity of the PWM, the output of the semiconductor refrigerating sheet is connected with a semiconductor refrigerating sheet, one surface of the semiconductor refrigerating sheet is tightly attached to the water tank, the other surface of the semiconductor refrigerating sheet is attached to the radiator, the polarity of output voltage is controlled to change the semiconductor to heat or refrigerate the water tank, and the duty ratio of PWM is controlled to control the temperature to stabilize the water tank;
the brushless direct current motor driving circuit adopts a special motor control chip A4931, an enable signal control chip A4931 outputs PWM, the enabled chip A4931 generates PWM signals to control 6 MOS (metal oxide semiconductor) tubes according to direction signals and pulse width signals received from an MCU (micro control unit), and outputs three-phase voltage signals to control the direction and the rotating speed of the motor; differential signals of the three-phase encoder are converted into TTL signals through AM26LV31 and fed back to A4931 to provide speed feedback, and speed pulse signals output by the chip A4931 are sent to the MCU to detect the running speed of the motor;
the flow sensor interface circuit adopts an RS485 interface, and the pressure sensor interface circuit and the blood oxygen sensor interface circuit respectively adopt serial TTL interfaces;
the power supply unit circuit converts the input DC24V into DC12V, DC5V and DC DC3.3V voltages to supply power to each unit module;
the wireless communication interface adopts a ZIGBEE module and a WIFI module, the ZIGBEE module is wirelessly connected with the blood gas analyzer, the biochemical analyzer, the ACT detector, the air-oxygen mixer and the injection pump, and the WIFI module is connected with the Internet;
the acousto-optic warning circuit is realized by a buzzer and an indicator light, and when an abnormal condition occurs, the buzzer is started to sound and the indicator light displays different colors to warn.
2. The in vitro life support control device according to claim 1, wherein the MCU main control unit circuit adopts STM32f7 series chip, which provides 8 serial ports, and the operation main frequency speed reaches 216MHZ, satisfying multiple serial ports and operation speed.
3. The in vitro life support control device according to claim 1, wherein the control device further comprises 2 pulse type knobs and 6 push-button switches, wherein one knob is used for coarse adjustment and the other knob is used for fine adjustment, the knobs and push-button switches are combined to set mode switching and target blood temperature, target rotational speed and target flow rate, and target set values are adjusted according to the push-button and knob signals and displayed on the display screen.
4. The in vitro life support control device according to claim 3, wherein the knob is a coded knob, two paths of square waves with 90-degree difference are generated during rotation, the order of the square waves generated by forward rotation and reverse rotation is opposite, the knob has a key function, and the set value is confirmed by pressing the knob after each adjustment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820944537.7U CN209847954U (en) | 2018-06-19 | 2018-06-19 | External life support control device |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108704172A (en) * | 2018-06-19 | 2018-10-26 | 广东顺德工业设计研究院(广东顺德创新设计研究院) | A kind of extracorporeal life supports control device and control method |
| CN111866459A (en) * | 2020-07-14 | 2020-10-30 | 汤国斌 | Extracorporeal membrane lung use scene monitoring system |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108704172A (en) * | 2018-06-19 | 2018-10-26 | 广东顺德工业设计研究院(广东顺德创新设计研究院) | A kind of extracorporeal life supports control device and control method |
| CN111866459A (en) * | 2020-07-14 | 2020-10-30 | 汤国斌 | Extracorporeal membrane lung use scene monitoring system |
| CN111866459B (en) * | 2020-07-14 | 2022-08-02 | 杰诺医学科技(杭州)有限公司 | Extracorporeal membrane lung use scene monitoring system |
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