CN209847158U - Electrical impedance imaging apparatus - Google Patents

Electrical impedance imaging apparatus Download PDF

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Publication number
CN209847158U
CN209847158U CN201920437823.9U CN201920437823U CN209847158U CN 209847158 U CN209847158 U CN 209847158U CN 201920437823 U CN201920437823 U CN 201920437823U CN 209847158 U CN209847158 U CN 209847158U
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China
Prior art keywords
module
data acquisition
electrical impedance
impedance imaging
imaging apparatus
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CN201920437823.9U
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张昕
王谊冰
张可
于洋
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Tsinghua University
Beijing Huarui Boshi Medical Imaging Technology Co Ltd
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Beijing Huarui Boshi Medical Imaging Technology Co Ltd
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Abstract

An electrical impedance imaging apparatus is provided. An electrical impedance imaging apparatus (100) according to the present invention generally comprises a sensing module (101), a data acquisition module (102), a communication module (103), a data processing module (104), an imaging display module (105) and a power module (106). According to the utility model discloses an electrical impedance imaging equipment (100) is applied to medical imaging, can utilize internal electrode to carry out multifrequency excitation and measurement simultaneously to the organism tissue that awaits measuring, utilizes the complex voltage signal that measures to carry out three-dimensional image and rebuilds, can just show simultaneously and in real time ventilate and fill the image to improve the quantity of data acquisition, improve data acquisition's speed, improve the measuring signal and to the sensitivity of internal tissue conductivity, be favorable to image analysis contrast, disease detection and diagnosis.

Description

Electrical impedance imaging apparatus
Technical Field
The utility model relates to an electrical impedance imaging technology, more specifically relate to a be applied to medical imaging's complex electrical impedance imaging equipment of three-dimensional while multifrequency.
Background
Electrical Impedance Tomography (EIT) is a non-invasive technique for reconstructing images of tissues in vivo targeting the Electrical resistivity distribution within the human body or other living organisms. The human body is a large biological electric conductor, each tissue and organ has certain impedance, and when the local organ of the human body is diseased, the impedance of the local organ is different from that of other parts, so that the disease of the organ of the human body can be diagnosed by measuring the impedance.
The existing electrical impedance imaging equipment uses an external electrode for data acquisition, namely, the electrodes are all arranged on the outer surface of a part to be measured of a human body. The signal thus acquired is not sensitive to electrical inhomogeneities in the living being. Thus, the EIT image reconstruction problem is often a serious morbidity problem. The actual measurement data often contains noise and the forward model used for image reconstruction often has errors, which will result in reconstructed images containing artifacts. These artifacts may even mask real objects, making subsequent image interpretation and medical mining efforts difficult.
During data acquisition, current electrical impedance imaging devices are energized with a constant current source one at a time and then measure the resulting voltage signal. After the generated voltage signal is measured, the electrical impedance imaging device switches the constant current source to the next position for excitation. When the number of the electrodes is large, the positions of the constant current sources need to be switched for many times, which limits the data acquisition speed to a certain extent, and is not favorable for real-time image reconstruction.
Therefore, it is desirable to provide an electrical impedance imaging apparatus, which is applied in the medical field, and performs a three-dimensional image reconstruction by performing simultaneous multi-frequency excitation and measurement on a biological tissue to be measured and using a measured complex voltage signal, thereby qualitatively or quantitatively measuring the electrical conductivity or permittivity characteristics of the biological tissue.
SUMMERY OF THE UTILITY MODEL
As described above, in order to solve the problems in the prior art, the present invention provides a three-dimensional simultaneous multi-frequency complex electrical impedance medical imaging apparatus, which performs simultaneous multi-frequency excitation and measurement on a biological tissue to be measured, and performs three-dimensional image reconstruction using a measured complex voltage signal, thereby qualitatively or quantitatively measuring the electrical conductivity or permittivity characteristics of the biological tissue.
According to the utility model discloses an embodiment, the utility model provides an electrical impedance imaging device. The electrical impedance imaging apparatus may comprise: the sensing module is fixed around the measured part of the human body in the form of an electrode array; the data acquisition module is connected with the sensing module so as to apply a constant current excitation signal to the sensing module and receive a complex voltage signal on an electrode array in the sensing module; the communication module is connected between the data processing module and the data acquisition module so as to transmit the complex voltage signal acquired by the data acquisition module to the data processing module and transmit a control command of the data processing module to the data acquisition module; the data processing module is connected to the data acquisition module so as to receive and process the complex voltage signal acquired by the data acquisition module; the imaging display module is connected to the data processing module so as to display the calculation result generated by the data processing module and the image; and the power supply modules are respectively connected to the modules to supply power.
In the electrical impedance imaging apparatus of the present invention, preferably, the electrode array may include at least 16 electrodes. The electrode array may include an intracorporeal electrode to be placed in a human body.
In the electrical impedance imaging apparatus of the present invention, preferably, the data acquisition module may further include a constant current source, and the light isolation is used between the constant current sources in the different data acquisition modules which are excited simultaneously.
In the electrical impedance imaging apparatus of the present invention, preferably, the data acquisition module may further include: a constant current source for applying excitation currents of a plurality of frequency components at the same time; a voltmeter which simultaneously measures complex voltage signals of a plurality of frequencies; the switch array comprises a plurality of analog switches, and is used for starting and stopping the application of the exciting current and the measurement of the complex voltage signal; the control logic circuit controls the switch in the switch array and the switching between the constant current source and the voltmeter; a multipath channel to transmit the excitation current to the sensing module and to receive the complex voltage signal from the sensing module.
Preferably, the electrical impedance imaging apparatus of the present invention may further comprise a calibration tray constructed using a resistance device so as to calibrate a systematic error and distribution parameter of the apparatus.
In the electrical impedance imaging apparatus of the present invention, preferably, the communication module takes the form of a serial interface circuit.
In the electrical impedance imaging apparatus of the present invention, preferably, the communication module and the data acquisition module are isolated from each other by an optical isolation.
According to the utility model discloses electrical impedance imaging equipment is applied to medical imaging, can utilize internal electrode to carry out multifrequency excitation and measurement simultaneously to the organism tissue that awaits measuring, utilizes the complex voltage signal that measures to carry out three-dimensional image and rebuilds to improve data acquisition's quantity, improve data acquisition's speed, improve the sensitivity of measuring signal to internal tissue conductivity, be favorable to image analysis contrast, disease detection and diagnosis.
Drawings
The invention is described below with reference to the accompanying drawings in conjunction with embodiments.
Fig. 1 is a block diagram of an electrical impedance imaging apparatus according to an embodiment of the present invention.
Fig. 2 is a block diagram of the data acquisition module of the electrical impedance imaging apparatus according to an embodiment of the present invention.
Detailed Description
The drawings are for illustration purposes only and are not to be construed as limiting the invention. The technical solution of the present invention will be further explained with reference to the accompanying drawings and examples.
Fig. 1 is a block diagram of an electrical impedance imaging apparatus 100 according to an embodiment of the present invention.
As shown in fig. 1, according to an embodiment of the present invention, an electrical impedance imaging apparatus 100 is generally comprised of a sensing module 101, a data acquisition module 102, a communication module 103, a data processing module 104, an imaging display module 105, and a power module 106. The sensing module 101 and the data acquisition module 102 are electrically isolated from the communication module 103, the data processing module 104, the imaging display module 105 and the power supply module 106.
The sensing module 101 is fixed around the measured part of the human body, such as the chest, brain, abdomen or limbs, and takes the form of an electrode array, such as an impedance band, an electrode vest, etc. According to a preferred embodiment of the present invention, each sensor module comprises at least 16 electrodes. Furthermore, in a preferred embodiment of the invention, the electrodes may take the form of intracorporeal electrodes. The internal electrode is an electrode that is placed in a human body such as an esophagus and a trachea. An electrical impedance imaging apparatus according to embodiments of the present invention may comprise a plurality of sensing modules 101. In fig. 1, three sensing modules are shown, sensing module 1#, sensing module 2#, and sensing module 3 #. It should be understood by those skilled in the art that the drawings are only schematic, and in practice, the number of sensing modules is not limited to three, and may be more or less, and collectively referred to as sensing modules, and all may be labeled as 101.
The data acquisition module 102 is configured to apply a constant current excitation signal to the sensing module 101 and receive and measure a complex voltage signal on an electrode array in the sensing module 101. The complex voltage signal can be expressed in terms of amplitude and phase, as well as in terms of real and imaginary parts. In fig. 1, three data acquisition modules are shown: the data acquisition module 1#, the data acquisition module 2#, and the data acquisition module 3# correspond to the sensing module 1#, the sensing module 2#, and the sensing module 3# respectively. It should be understood by those skilled in the art that the illustration is merely schematic, and in practice, the number of data acquisition modules is not limited to three, and may be more or less, and collectively referred to as data acquisition modules, and all may be labeled as 102.
Fig. 2 is a block diagram of the data acquisition module 102 of the electrical impedance imaging apparatus 100 according to an embodiment of the present invention. As shown in fig. 2, the data acquisition module 102 includes a multiplexer 1021, a switch array 1022, a control logic circuit 1023, a constant current source 1024, and a voltage meter 1025. The multiplexer 1021 is used to transmit the excitation current to the sensing block 101 and to receive the complex voltage signal from the sensing block 101. The switch array 1022 includes a number of analog switches for turning on and off the application of the excitation current and the measurement of the complex voltage signal. The control logic 1023 is used to control the switches in the switch array 1022 and the switching between the constant current source 1024 and the voltage meter 1025 and may be implemented using a Field Programmable Gate Array (FPGA). To increase the rate of data collection, constant current sources (not shown in fig. 1) in different data collection modules (e.g., data collection module 1#, data collection module 2#, and data collection module 3 #) may be energized simultaneously. In order to avoid the danger of short circuit caused by a plurality of zero potentials generated on the human body when the human body is excited simultaneously, the constant current sources excited simultaneously are isolated by light. In addition, in order to utilize the response characteristics of biological tissues to signal frequencies, a simultaneous multi-frequency excitation and measurement method is adopted. Specifically, the constant current source 1024 in fig. 2 can simultaneously apply excitation currents of a plurality of frequency components, and the voltmeter 1025 can correspondingly simultaneously measure complex voltage signals of a plurality of frequencies.
Returning to fig. 1, the communication module 103 is configured to transmit the voltage data (complex voltage signal) acquired by the data acquisition module 102 to the data processing module 104, and may also transmit a control command of the data processing module 104 to the data acquisition module 102. The communication module 103 may take the form of a serial interface circuit. The communication module 103 and the data acquisition module 102 are isolated from each other by light.
The data processing module 104 is configured to perform signal processing and image reconstruction on the complex voltage signal acquired by the data acquisition module 102. The module 104 may be a computer or other device with computing function and a corresponding computer program. The module 104 uses signal processing methods to detect if the measurement or excitation range is exceeded and to detect poor electrode contact or electrode detachment. The module 104 has a three-dimensional image reconstruction function. Conventionally, the module 104 may use time domain differentiation or frequency domain differentiation for differential imaging. Differential imaging is reconstruction using the difference between measured data at two times or two frequency components, and the reconstructed image reflects the amount of change in the electrical conductivity or permittivity of the biological tissue between the two times or two frequency components. The module 104 may also perform direct imaging. By direct imaging, it is specifically meant that the reconstructed image reflects the absolute conductivity or permittivity values of the biological tissue.
The imaging display module 105 is used for displaying the calculation result generated by the data processing module and the image. The module 105 may be a display. In a preferred embodiment, the imaging display module 105 may display a three-dimensional reconstructed image corresponding to the data processing module 104 with a three-dimensional image reconstruction function. Further, in a preferred embodiment of the present invention, the imaging display module 105 may display the ventilation and perfusion images simultaneously and in real time.
In addition, as will be understood by those skilled in the art, the power module 106 is used to supply power to the sensing module 101, the data acquisition module 102, the communication module 103, the data processing module 104, and the imaging display module 105 described above.
Preferably, the electrical impedance imaging apparatus according to the embodiment of the present invention may use a resistor device to form a calibration disk (not shown) for calibrating the system error and distribution parameters of the apparatus.
Below, to the utility model discloses an equipment compares with current technique to summarize the utility model's advantage.
The utility model discloses an equipment utilization multifrequency excitation and measurement simultaneously can utilize thereby the quantity that biological tissue improved the data collection to signal frequency's response characteristic on the one hand, and on the other hand can improve data acquisition's speed greatly.
The utility model discloses an equipment utilizes signal processing can the automatic detection electrode contact not good or the situation that the electrode drops to take corresponding measure.
The utility model has the outstanding characteristic that the internal electrode is utilized to carry out data acquisition. This greatly increases the sensitivity of the measurement signal to the electrical conductivity of the internal tissue of the human or living body, in particular the internal tissue of the thorax.
The utility model discloses can use a plurality of constant current sources to encourage in order to improve data acquisition speed simultaneously.
The utility model discloses an in the equipment, sensing module and data acquisition module and communication module, data processing module, formation of image display module, power module realize optoisolation electrically, can reduce the electrical interference to the data acquisition process greatly.
The utility model discloses except can carrying out the difference formation of image, still carry out direct imaging to the conductivity and the dielectric constant of quantitative measurement human tissue.
The utility model discloses rebuild and show three-dimensional image, can show the three-dimensional structure of human tissue or organ to more be favorable to image analysis, disease detection and diagnosis.
Another outstanding feature of the utility model is that the ventilation and perfusion images can be displayed simultaneously, thereby facilitating the comparative analysis.
Furthermore, the utility model discloses use resistive device to constitute the calibration dish, calibrate the systematic error and the distribution parameter of equipment to reduce the influence of systematic error and distribution parameter to measured data greatly.
Various embodiments and implementations of the present invention have been described above. However, the spirit and scope of the present invention is not limited thereto. Those skilled in the art will be able to devise many more applications in accordance with the teachings of the present invention, which are within the scope of the present invention.
That is, the above embodiments of the present invention are merely examples for clearly illustrating the present invention, and are not intended to limit the embodiments of the present invention. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. Any modification, replacement or improvement made within the spirit and principle of the present invention should be included in the protection scope of the claims of the present invention.

Claims (8)

1. An electrical impedance imaging apparatus, characterized in that the apparatus comprises:
the sensing module is fixed around the measured part of the human body in the form of an electrode array;
the data acquisition module is connected with the sensing module so as to apply a constant current excitation signal to the sensing module and receive a complex voltage signal on an electrode array in the sensing module;
the communication module is connected between the data processing module and the data acquisition module so as to transmit the complex voltage signal acquired by the data acquisition module to the data processing module and transmit a control command of the data processing module to the data acquisition module;
the data processing module is connected to the data acquisition module so as to receive and process the complex voltage signal acquired by the data acquisition module;
the imaging display module is connected to the data processing module so as to display the calculation result generated by the data processing module and the image;
and the power supply modules are respectively connected to the modules to supply power.
2. The electrical impedance imaging device of claim 1, wherein the electrode array comprises at least 16 electrodes.
3. The electrical impedance imaging device of claim 1 or 2, wherein the electrode array comprises intracorporeal electrodes for placement in a human body.
4. The electrical impedance imaging apparatus of claim 1, wherein the data acquisition modules further comprise constant current sources, and wherein optical isolation is employed between constant current sources in different data acquisition modules that are simultaneously energized.
5. The electrical impedance imaging apparatus of claim 1, wherein the data acquisition module further comprises:
a constant current source for applying excitation currents of a plurality of frequency components at the same time;
a voltmeter which simultaneously measures complex voltage signals of a plurality of frequencies;
the switch array comprises a plurality of analog switches, and is used for starting and stopping the application of the exciting current and the measurement of the complex voltage signal;
the control logic circuit controls the switch in the switch array and the switching between the constant current source and the voltmeter;
a multipath channel to transmit the excitation current to the sensing module and to receive the complex voltage signal from the sensing module.
6. The electrical impedance imaging apparatus of claim 1, wherein the apparatus further comprises a calibration disk constructed using resistive devices to calibrate systematic errors and distribution parameters of the apparatus.
7. The electrical impedance imaging apparatus of claim 1, wherein the communication module takes the form of a serial interface circuit.
8. The electrical impedance imaging apparatus of claim 1, wherein optical isolation is employed between the communication module and the data acquisition module.
CN201920437823.9U 2019-04-02 2019-04-02 Electrical impedance imaging apparatus Active CN209847158U (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109864712A (en) * 2019-04-02 2019-06-11 北京华睿博视医学影像技术有限公司 Electrical impedance imaging device and method
CN115670422A (en) * 2023-01-04 2023-02-03 北京华睿博视医学影像技术有限公司 Electrical impedance imaging system

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109864712A (en) * 2019-04-02 2019-06-11 北京华睿博视医学影像技术有限公司 Electrical impedance imaging device and method
CN115670422A (en) * 2023-01-04 2023-02-03 北京华睿博视医学影像技术有限公司 Electrical impedance imaging system
CN115670422B (en) * 2023-01-04 2023-03-17 北京华睿博视医学影像技术有限公司 Electrical impedance imaging system

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Effective date of registration: 20231106

Address after: 102629 213, floor 2, building 10, No. 9, Tianfu Road, Daxing District, Beijing

Patentee after: BEIJING HUARUI BOSHI MEDICAL IMAGE TECHNOLOGY Co.,Ltd.

Patentee after: TSINGHUA University

Address before: Room 431-5, building 3, No. 538, yongfengtun, Haidian District, Beijing 100094

Patentee before: BEIJING HUARUI BOSHI MEDICAL IMAGE TECHNOLOGY Co.,Ltd.