CN209784283U - High performance liquid chromatography measuring equipment - Google Patents

Abstract

The utility model discloses a high performance liquid chromatography measuring equipment, the on-line screen storage device comprises a base, base top both sides are equipped with the teeter chamber respectively and detect the room, the teeter chamber is kept away from and is detected room one side top and be equipped with crushing room, it is equipped with the backup pad to smash room one side of keeping away from the teeter chamber, the backup pad top is equipped with the motor, the motor output end is equipped with the pivot one that runs through crushing room, the pivot other end is equipped with the bevel gear one that extends to the teeter chamber inside, it locates the blade group of a pivot outside to smash the indoor portion and be equipped with the feed inlet to be equipped with the cover, it is equipped with the. The utility model discloses a high performance liquid chromatography measuring equipment, overall design is reasonable, and easy operation has increased the functionality of survey device, has solved the determinand and has fused inadequately with the mobile phase, and impurity filtering can not clear up, and the filter screen can not change the scheduling problem, greatly increased the practicality of this design.

Description

High performance liquid chromatography measuring equipment

Technical Field

The utility model relates to a detect technical field, in particular to high performance liquid chromatography measuring equipment.

Background

High performance liquid chromatography, also known as high pressure liquid chromatography, high speed liquid chromatography, etc., uses liquid as a mobile phase, adopts a high pressure transfusion system, pumps the mobile phase such as single solvents with different polarities or mixed solvents with different proportions, buffer solution, etc. into a chromatographic column filled with a stationary phase, and after each component in the column is separated, the components enter a detector for detection, thereby realizing the analysis of a sample. Traditional high performance liquid chromatography survey equipment fuses the processing to determinand and mobile phase mutually not comprehensive, and filter equipment uses for a long time, and unable clearance, the difference of stationary phase simultaneously also is different to the filter screen requirement, and then makes equipment survey article inefficiency and survey the type simplification.

SUMMERY OF THE UTILITY MODEL

The utility model discloses a main aim at provides a high performance liquid chromatography survey equipment, can effectively solve in the background art to determinand and with the mobile phase fuse the processing not comprehensive mutually, the unable filter screen of changing of clearing up, equipment survey article inefficiency and survey the problem that the kind is simplified.

In order to achieve the above purpose, the utility model adopts the following technical scheme:

A high performance liquid chromatography measuring device comprises a base, wherein an agitating chamber and a detecting chamber are respectively arranged on two sides of the top end of the base, the top of one side, away from the detecting chamber, of the agitating chamber is provided with a crushing chamber, one side, away from the agitating chamber, of the crushing chamber is provided with a supporting plate, the top end of the supporting plate is provided with a motor, the output end of the motor is provided with a first rotating shaft penetrating through the crushing chamber, the other end of the rotating shaft is provided with a first conical gear extending into the agitating chamber, the inside of the crushing chamber is provided with a blade group sleeved outside the first rotating shaft, the top end, outside the crushing chamber, close to the motor is provided with a feed inlet, the bottom of one side, inside the crushing chamber, is provided with a channel penetrating to the inner wall of the agitating chamber, the first conical gear is far away from one side of the crushing, the two tops of pivot are equipped with the bearing frame that is connected with the inside top of agitator chamber, the two outside covers of pivot are equipped with and are located the stirring leaf group of two below bevel gear, the outside top of agitator chamber is kept away from smash room one side and is equipped with mobile phase room, mobile phase room bottom is equipped with and runs through the mobile phase pipeline of agitator chamber inside, the outside bottom of agitator chamber is close to detection room one side is equipped with the discharging pipe, the outside bottom of detection room is close to agitator chamber one side be equipped with the inlet pipe of discharging pipe looks adaptation, the discharging pipe with be connected through detachable filter equipment between the inlet pipe, the detection room inner wall is close to inlet pipe one side is equipped with the high pressure transfer pump, the high pressure transfer pump input is connected with inlet pipe one end, be equipped with the chromatographic column that is located the high pressure, be equipped with on the detection room inner wall and be located the injector of chromatographic column top, the detection room inside top is equipped with the detector, the detection room inside bottom is equipped with and is located the fraction collector of detector below, the high pressure transfer pump the chromatographic column the injector the detector with the fraction collector loops through a plurality of connecting pipes and is connected, the detection room is close to fraction collector one side is equipped with the chamber door, the detection room outside top is equipped with the display.

Preferably, filter equipment includes the filter tube, the filter tube is inside to be equipped with the filter screen, the outside both ends of filter tube are equipped with solid fixed ring one respectively, the discharging pipe with the inlet pipe outside is equipped with respectively the cover with gu fixed ring two of a fixed ring assorted, gu fixed ring one with gu be connected through a plurality of fixing bolt between the fixed ring two, the fixing bolt other end is equipped with the nut.

Preferably, the discharge pipe with the inlet pipe all with be equipped with the sealing washer between the filter tube.

Preferably, valves are arranged on the mobile phase pipeline and the discharge pipe, and a transparent observation port is arranged on one side of the mobile phase chamber.

Preferably, the bottom end outside the crushing chamber is provided with a supporting column connected with the top end of the base.

Compared with the prior art, the utility model discloses following beneficial effect has: through setting up the motor, the mating reaction of pivot one and blade group, smash the abundant cutting of determinand, be convenient for fuse with the mobile phase, through setting up bevel gear one, bevel gear two, the mating reaction of pivot two and stirring blade group, make the mobile phase with smash the abundant integration of thing, through setting up convenient to detach's filter equipment, can in time clear up the impurity after filtering, and change the filter screen, the different stationary phase separation sample of cooperation, the global design is reasonable, and the operation is thus simple, the functionality of survey device has been increased, it is not abundant with the mobile phase fusion to have solved the determinand, filtering impurity can not clear up, the filter screen can not change the scheduling problem, greatly increased the practicality of this design.

drawings

FIG. 1 is a schematic view of the overall structure of a high performance liquid chromatography measuring apparatus according to the present invention;

Fig. 2 is an enlarged schematic view of a point a in fig. 1.

In the figure: 1. a base; 2. a crushing chamber; 3. a stirring chamber; 4. a detection chamber; 5. a support plate; 6. a motor; 7. a first rotating shaft; 8. a first conical gear; 9. a blade set; 10. a channel; 11. a feed inlet; 12. a second rotating shaft; 13. a second bevel gear; 14. a bearing seat; 15. stirring the leaf group; 16. a mobile phase conduit; 17. a mobile phase chamber; 18. a discharge pipe; 19. a feed pipe; 20. a high-pressure infusion pump; 21. a chromatographic column; 22. a detector; 23. a fraction collector; 24. a connecting pipe; 25. a box door; 26. a sample injector; 27. a filter tube; 28. a filter screen; 29. a first fixing ring; 30. a second fixing ring; 31. fixing the bolt; 32. a nut; 33. a seal ring; 34. a display.

Detailed Description

In order to make the technical means, creation features, achievement purposes and functions of the present invention easy to understand, the present invention is further described below with reference to the following embodiments.

In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "both ends", "one end", "the other end" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description and simplification of description, but do not indicate or imply that the device or element to which the reference is made must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. Furthermore, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.

In the description of the present invention, it is to be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "disposed," "connected," and the like are to be construed broadly, and for example, "connected" may be either fixedly connected or detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present invention can be understood in specific cases to those skilled in the art.

As shown in figure 1-2, a high performance liquid chromatography measuring device comprises a base 1, wherein both sides of the top end of the base 1 are respectively provided with an agitating chamber 3 and a detecting chamber 4, the top of one side of the agitating chamber 3, which is far away from the detecting chamber 4, is provided with a crushing chamber 2, one side of the crushing chamber 2, which is far away from the agitating chamber 3, is provided with a supporting plate 5, the top end of the supporting plate 5 is provided with a motor 6, the output end of the motor 6 is provided with a first rotating shaft 7 which penetrates through the crushing chamber 2, the other end of the rotating shaft is provided with a first conical gear 8 which extends into the agitating chamber 3, the inside of the crushing chamber 2 is provided with a blade group 9 which is sleeved outside the first rotating shaft 7, one side of the top end of the outside of the crushing chamber 2, which is close to the motor 6, the bottom of one side of the inside of the crushing chamber 2 is provided, a bearing seat 14 connected with the top end inside the stirring chamber 3 is arranged at the top end of the second rotating shaft 12, a stirring blade group 15 positioned below the second bevel gear 13 is sleeved outside the second rotating shaft 12, a mobile phase chamber 17 is arranged at one side of the top end outside the stirring chamber 3, which is far away from the crushing chamber 2, a mobile phase pipeline 16 penetrating through the inside of the stirring chamber 3 is arranged at the bottom end of the mobile phase chamber 17, a discharge pipe 18 is arranged at one side of the bottom end outside the stirring chamber 3, which is close to the detection chamber 4, a feed pipe 19 matched with the discharge pipe 18 is arranged at one side of the bottom end outside the detection chamber 4, which is close to the stirring chamber 3, the discharge pipe 18 is connected with the feed pipe 19 through a detachable filtering device, a high-pressure infusion pump 20 is arranged at one side of the inner wall of the detection chamber 4, the input end of the high-pressure infusion, the top end in the detection chamber 4 is provided with a detector 22, the bottom end in the detection chamber 4 is provided with a fraction collector 23 positioned below the detector 22, a high-pressure infusion pump 20, a chromatographic column 21, a sample injector 26, the detector 22 and the fraction collector 23 are sequentially connected through a plurality of connecting pipes 24, one side of the detection chamber 4 close to the fraction collector 23 is provided with a box door 25, and the top end outside the detection chamber 4 is provided with a display 34;

The filtering device comprises a filtering pipe 27, a filtering net 28 is arranged in the filtering pipe 27, two fixing rings 29 are respectively sleeved at two ends of the outside of the filtering pipe 27, a fixing ring II 30 matched with the fixing ring I29 is respectively sleeved outside the discharging pipe 18 and the feeding pipe 19, the fixing ring I29 and the fixing ring II 30 are connected through a plurality of fixing bolts 31, and nuts 32 are arranged at the other ends of the fixing bolts 31; sealing rings 33 are arranged between the discharge pipe 18 and the feed pipe 19 and the filtering pipe 27; valves are arranged on the mobile phase pipeline 16 and the discharge pipe 18, and a transparent observation port is arranged on one side of the mobile phase chamber 17; the outside bottom of crushing room 2 is equipped with the support column that is connected with base 1 top.

it should be noted that, the utility model relates to a high performance liquid chromatography measuring device, when in use, the staff puts the object to be measured into the crushing chamber 2 from the feed inlet 11, the motor 6 is started, and then the first drive shaft 7 drives the blade set 9 to rotate, the object to be measured is crushed, the crushed object to be measured enters the stirring chamber 3 through the channel 10, the valve at one side of the rotary flow phase pipeline 16 controls the proper amount of mobile phase in the mobile phase chamber 17 to enter the stirring chamber through the transparent viewing port, the first drive shaft 7 drives the first bevel gear 8 to rotate, and then the second drive shaft 13 meshed with the first bevel gear 8 rotates, and then the second drive shaft 12 drives the stirring blade set 15 to rotate, stir the object to be measured of mixed mobile phase, the valve on the discharge pipe 18 is twisted after the stirring is completed, and then the mixture filters impurities through the filtering device, and then flows into the high pressure infusion pump 20 through the feed pipe 19, the high-pressure infusion pump 20 applies high pressure to input an object to be detected into the chromatographic column 21 through a connecting pipe, a sample analyzed by the chromatographic column 21 is input into the detector 22 through the sample injector 26 for detection, a detection result is displayed through the display 34, the detected sample flows into the fraction collector 23, the fraction collector 23 can be taken out through the box door 25, when the filter screen 28 needs to be replaced, a valve on the discharge pipe 18 is closed, the nut 32 is loosened, the fixing bolt 31 is taken out, the filter pipe 27 is further taken out, the filter pipe 27 is placed between the discharge pipe 18 and the feed pipe 19 after replacement and cleaning, the fixing bolt 31 is put in, the nut 32 is twisted, and the filter pipe 27 is further fixed.

the basic principles and the main features of the invention and the advantages of the invention have been shown and described above. It will be understood by those skilled in the art that the present invention is not limited to the above embodiments, and that the foregoing embodiments and descriptions are provided only to illustrate the principles of the present invention without departing from the spirit and scope of the present invention. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (5)

1. A high performance liquid chromatography assay device characterized by: comprises a base (1), wherein both sides of the top end of the base (1) are respectively provided with a stirring chamber (3) and a detection chamber (4), the stirring chamber (3) is far away from the top of one side of the detection chamber (4) and is provided with a crushing chamber (2), the crushing chamber (2) is far away from one side of the stirring chamber (3) and is provided with a support plate (5), the top end of the support plate (5) is provided with a motor (6), the output end of the motor (6) is provided with a first rotating shaft (7) which penetrates through the crushing chamber (2), the other end of the rotating shaft is provided with a first conical gear (8) which extends into the stirring chamber (3), the crushing chamber (2) is internally provided with a blade group (9) which is sleeved outside the first rotating shaft (7), the outer top end of the crushing chamber (2) is close to one side of the motor (6) and is provided with a feed inlet (11), the bottom of one side inside, keep away from conical gear (8) smash room (2) one side and be equipped with pivot two (12), pivot two (12) outside cover be equipped with conical gear two (13) that conical gear (8) engaged with, pivot two (12) top be equipped with bearing frame (14) that the inside top of teeter chamber (3) is connected, pivot two (12) outside cover is equipped with and is located stirring leaf group (15) of conical gear two (13) below, teeter chamber (3) outside top is kept away from smash room (2) one side and is equipped with mobile phase room (17), mobile phase room (17) bottom is equipped with and runs through mobile phase pipeline (16) of teeter chamber (3) inside, teeter chamber (3) outside bottom is close to it is equipped with discharging pipe (18) to detect room (4) one side, it is close to detect room (4) outside bottom stir chamber (3) one side be equipped with inlet pipe (19) of discharging pipe (18) looks adaptation, discharging pipe (18) with connect through detachable filter equipment between inlet pipe (19), it is close to detect room (4) inner wall inlet pipe (19) one side is equipped with high-pressure infusion pump (20), high-pressure infusion pump (20) input with inlet pipe (19) one end is connected, be equipped with on detecting room (4) inner wall and be located chromatographic column (21) of high-pressure infusion pump (20) top, be equipped with on detecting room (4) inner wall and be located injector (26) of chromatographic column (21) top, the inside top of detecting room (4) is equipped with detector (22), the inside bottom of detecting room (4) is equipped with and is located fraction collector (23) of detector (22) below, high-pressure infusion pump (20), chromatographic column (21), injector (26), detector (22) with fraction collector (23) loop through a plurality of connecting pipes (24) and be connected, and a box door (25) is arranged on one side of the detection chamber (4) close to the fraction collector (23), and a display (34) is arranged at the top end of the outside of the detection chamber (4).

2. The high performance liquid chromatography assay apparatus according to claim 1, wherein: filter equipment includes filter tube (27), filter tube (27) inside is equipped with filter screen (28), the outside both ends of filter tube (27) are equipped with solid fixed ring one (29) respectively, discharging pipe (18) with inlet pipe (19) outside is equipped with respectively the cover with gu fixed ring two (30) of fixed ring one (29) assorted, gu fixed ring one (29) with gu be connected through a plurality of fixing bolt (31) between fixed ring two (30), fixing bolt (31) other end is equipped with nut (32).

3. The high performance liquid chromatography assay apparatus according to claim 2, wherein: the discharging pipe (18) with the feeding pipe (19) all with be equipped with sealing washer (33) between filter tube (27).

4. The high performance liquid chromatography assay apparatus according to claim 1, wherein: valves are arranged on the mobile phase pipeline (16) and the discharge pipe (18), and a transparent observation port is arranged on one side of the mobile phase chamber (17).

5. The high performance liquid chromatography assay apparatus according to claim 1, wherein: the bottom end of the outer part of the crushing chamber (2) is provided with a supporting column connected with the top end of the base (1).