CN209770372U - Device for measuring extracellular fluid electrical impedance and total moisture electrical impedance - Google Patents
Device for measuring extracellular fluid electrical impedance and total moisture electrical impedance Download PDFInfo
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- CN209770372U CN209770372U CN201920170857.6U CN201920170857U CN209770372U CN 209770372 U CN209770372 U CN 209770372U CN 201920170857 U CN201920170857 U CN 201920170857U CN 209770372 U CN209770372 U CN 209770372U
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Abstract
the utility model discloses a device for measuring extracellular fluid impedance and total moisture impedance, which comprises a current excitation generation module and an impedance measurement module; the current excitation generating module comprises a current excitation source connected with the microprocessor, the current excitation source is connected with a first stimulating electrode and a second stimulating electrode, the first stimulating electrode is positioned at the measured part of the wrist, and the second stimulating electrode is positioned at the measured part of the ankle on the same side; the impedance measuring module comprises two measuring electrodes, the two measuring electrodes are arranged between the two stimulating electrodes, the two measuring electrodes are connected with the signal conditioning circuit, the signal conditioning circuit is connected with the microprocessor through the amplitude-phase detecting module, and the amplitude-phase detecting module is also connected with the reference signal and used for extracting the amplitude ratio and the phase difference of the measuring signal and the reference signal; and the microprocessor calculates impedance values according to the stimulation current values with different frequencies and the corresponding measured potential values. Can obtain accurate extracellular fluid electrical impedance and total moisture electrical impedance values, and is favorable for comprehensive analysis.
Description
Technical Field
The utility model relates to an extracellular fluid electrical impedance and total moisture electrical impedance analysis technical field specifically relate to a measuring device of multifrequency extracellular fluid electrical impedance and total moisture electrical impedance.
Background
Bioimpedance is an important part of the analysis of biological characteristics, and has become a major concern in the health field. In particular, the multi-frequency bioelectrical impedance analysis can accurately measure the distribution of body fluid and the edema state of the human body.
Biological tissue in the low frequency region (<1MHz) the electrochemical properties of the extracellular and intracellular fluids are close to electrical resistance, while the cell membrane is equivalent to capacitance. The most widespread three-component equivalent circuit is shown in FIG. 1, where R isi、Re、CmThe equivalent resistance of intracellular fluid, the equivalent resistance of extracellular fluid and the equivalent capacitance of cell membrane are respectively.
the track of the equivalent circuit model of the three elements of the biological impedance on the complex plane is a semicircle of a fourth quadrant, which is called an impedance circle diagram, and the electrical impedance characteristic equation is as follows:
Wherein R is0、R∞And τ represent a resistance value at a frequency of 0, a resistance value at an infinite frequency, and a time constant, respectively.
However, it is difficult to obtain a true and accurate bio-impedance value due to a change in body weight, body fluid solid content or fat content.
SUMMERY OF THE UTILITY MODEL
in order to solve the technical problem, the utility model provides a measuring device of extracellular fluid electrical impedance and total moisture electrical impedance can obtain multiple true accurate biological impedance, including extracellular fluid electrical impedance and total moisture electrical impedance value.
The utility model adopts the technical proposal that:
The device for measuring the extracellular fluid electrical impedance and the total moisture electrical impedance comprises a current excitation generation module and an impedance measurement module;
The current excitation generating module comprises a current excitation source connected with the microprocessor, the current excitation source is connected with a first stimulating electrode and a second stimulating electrode, the first stimulating electrode is positioned at a first tested part, and the second stimulating electrode is positioned at a second tested part on the same side;
The impedance measuring module comprises a first measuring electrode and a second measuring electrode, the first measuring electrode and the second measuring electrode are arranged between the two stimulating electrodes, the first measuring electrode and the second measuring electrode are connected with a signal conditioning circuit, the signal conditioning circuit is connected with the microprocessor through an amplitude-phase detecting module, and the amplitude-phase detecting module is also connected with a reference signal and used for extracting the amplitude ratio and the phase difference of the measuring signal and the reference signal;
The microprocessor calculates impedance value according to the stimulation current values of different frequencies and the corresponding measured potential values, and takes the impedance measured at low frequency as the extracellular fluid electrical impedance ZECWImpedance measured at high frequency as total moisture impedance ZTBW。
In the preferred technical scheme, the stimulating electrode adopts a strip electrode with the width of 0.8 cm or a phoenix rubber electrode with the diameter of 3 cm or a disposable ECG Ag/AgCI pasting electrode.
In a preferred technical scheme, the microprocessor is further connected with a wireless communication module, the wireless communication module is connected with an external terminal, and the external terminal is used for recording and storing data and processing the data to obtain a data curve graph.
In the preferred technical scheme, the frequency range of the stimulating current is 20-300 kHz, and the magnitude of the stimulating current is 0.3-3.0 mA.
compared with the prior art, the beneficial effects of the utility model are that:
The utility model discloses can avoid because of the change of human weight, body fluid solid content or fat content, obtain multiple true accurate bioimpedance, including extracellular fluid electrical impedance and total moisture electrical impedance value, be favorable to carrying out comprehensive evaluation analysis. The extracellular fluid content and the total water content can be calculated, and the renal failure condition of the tested person can be comprehensively obtained according to an edema evaluation formula. The renal failure condition of the human body is analyzed by integrating the multi-position edema condition, so that misjudgment caused by single condition analysis can be avoided.
Drawings
The invention will be further described with reference to the following drawings and examples:
FIG. 1 is a diagram of an equivalent circuit model of extracellular fluid electrical impedance and total water electrical impedance;
FIG. 2 is a schematic diagram of the measuring method of the extracellular fluid impedance and the total moisture impedance of the present invention;
Fig. 3 is a schematic block diagram of the device for measuring the extracellular fluid impedance and the total moisture impedance of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in detail with reference to the accompanying drawings. It should be understood that the description is intended to be illustrative only and is not intended to limit the scope of the present invention. Moreover, in the following description, descriptions of well-known structures and techniques are omitted so as to not unnecessarily obscure the concepts of the present invention.
Examples
Referring to fig. 2 and 3, an extracellular fluid electrical impedance and total moisture electrical impedance measuring apparatus includes a microprocessor 11 attached to a wrist and an ankle of a measured object 13, and a current excitation generating module and an impedance measuring module respectively connected to the microprocessor 11. Wherein the content of the first and second substances,
The current excitation generating module comprises: and the current excitation source 12 is connected with the microprocessor 11, the current excitation source is a DDS module, and the current excitation source 12 is connected with the two stimulation electrodes. The microprocessor 11 is used for controlling the DDS module 12 to generate sinusoidal current meeting the human body safety current requirement. The stimulating electrodes comprise a first stimulating electrode 3a and a second stimulating electrode 3b, and are used for injecting the generated sinusoidal current to a tested part of a human body. The stimulating electrode can adopt a strip electrode with the width of 0.8 cm or a karaya gum electrode with the diameter of 3 cm or a disposable ECG Ag/AgCI pasting electrode.
the impedance measurement module includes: two measuring electrodes for measuring extracellular fluid electrical impedance and total moisture electrical impedance, a signal conditioning circuit 15 and an amplitude-phase detection module 16; the amplitude and phase detection module 16 is connected with the microprocessor 11. The measuring electrodes comprise a first measuring electrode 4a and a second measuring electrode 4 b; the two measuring electrodes are arranged between the two stimulating electrodes and used for collecting the potential difference between two points of stimulating current injected into the measured part and transmitting a potential difference signal to the signal conditioning circuit 15. The signal conditioning circuit 15 performs multi-stage amplification and filtering processing on the acquired signal and transmits the signal to the amplitude-phase signal detection module 16. The amplitude-phase signal detection module 16 is further connected with a reference signal 14, the reference signal 14 is a signal obtained by passing a current excitation source through a constant value resistor, the reference signal 14 is also connected to the amplitude-phase signal detection module 16 through a signal conditioning circuit, and the amplitude-phase signal detection module 16 is used for extracting an amplitude ratio and a phase difference between a measurement signal and a reference signal and sending the amplitude ratio and the phase difference to the microprocessor 11.
As shown in fig. 2, the measured positions are specifically: the first measuring electrode 4a and the first stimulating electrode 3a are placed at the wrist part, and the second measuring electrode 4b and the second stimulating electrode 3b are placed at the ankle part at the same side, so that more accurate bio-impedance values can be measured.
The system calibration module 17 is used for reducing errors brought to the amplitude and phase detection result by the non-ideal matching state of the analog components, obtaining amplitude and phase functions corresponding to each frequency point by linear regression fitting of a least square method, and calculating to obtain an actual biological impedance value.
A wireless communication module 18 connected with the microprocessor 11, such as a Bluetooth communication module, can also be arranged, and is controlled by the microprocessor 11, and is connected with an external intelligent terminal to realize communication for post data processing, storage and display.
the method for measuring the extracellular fluid electrical impedance and the total moisture electrical impedance by the measuring device based on the extracellular fluid electrical impedance and the total moisture electrical impedance comprises the following steps:
Step S1: controlling a current excitation generating module to generate stimulating currents with different frequencies through a microprocessor, and injecting the stimulating currents into a tested part through a first stimulating electrode and a second stimulating electrode of the current excitation generating module; the frequency range of the stimulating current is 20-300 kHz, and the magnitude of the stimulating current is 0.3-3.0 mA.
Step S2: measuring the potential between the measured parts provided with the stimulating electrodes through the first measuring electrode and the second measuring electrode, and recording the numerical values of the potential under different frequencies; the first measurement electrode and the second measurement electrode may be placed at a plurality of edema sites.
Step S3: calculating to obtain impedance value according to the stimulation current values of different frequencies and the corresponding measured potential value, and measuring at low frequency to obtain extracellular fluid impedance ZECWMeasuring at high frequency to obtain the total moisture impedance ZTBW. And performing multiple regression analysis by combining the weight w and the height h of the measured object to obtain the ECW and the TBW.
Can be based onObtaining the index of the general edema and integrally evaluating the renal failure condition of the tested person.
The utility model discloses the device contains bluetooth communication module, can realize simple measurement every day, and long-term monitor system just is in the software with data transmission to external equipment through the bluetooth to carry out record and storage with these data, draw the data curve graph, realize long-term control aassessment purpose.
it is to be understood that the above-described embodiments of the present invention are merely illustrative of or explaining the principles of the invention and are not to be construed as limiting the invention. Therefore, any modification, equivalent replacement, improvement and the like made without departing from the spirit and scope of the present invention should be included in the protection scope of the present invention. Further, it is intended that the appended claims cover all such variations and modifications as fall within the scope and boundaries of the appended claims or the equivalents of such scope and boundaries.
Claims (4)
1. The device for measuring the extracellular fluid electrical impedance and the total moisture electrical impedance is characterized by comprising a current excitation generation module and an impedance measurement module;
The current excitation generating module comprises a current excitation source connected with the microprocessor, the current excitation source is connected with a first stimulating electrode and a second stimulating electrode, the first stimulating electrode is positioned at a first tested part, and the second stimulating electrode is positioned at a second tested part on the same side;
the impedance measuring module comprises a first measuring electrode and a second measuring electrode, the first measuring electrode and the second measuring electrode are arranged between the two stimulating electrodes, the first measuring electrode and the second measuring electrode are connected with a signal conditioning circuit, the signal conditioning circuit is connected with the microprocessor through an amplitude-phase detecting module, and the amplitude-phase detecting module is also connected with a reference signal and used for extracting the amplitude ratio and the phase difference of the measuring signal and the reference signal;
The microprocessor calculates impedance value according to the stimulation current values of different frequencies and the corresponding measured potential values, and takes the impedance measured at low frequency as the extracellular fluid electrical impedance ZECWimpedance measured at high frequency as total moisture impedance ZTBW。
2. The device for measuring the extracellular fluid electrical impedance and the total moisture electrical impedance of claim 1, wherein the stimulation electrode is a strip electrode with a width of 0.8 cm or a karaya gum electrode with a diameter of 3 cm or a disposable ECG Ag/AgCI paste electrode.
3. The device for measuring the extracellular fluid electrical impedance and the total moisture electrical impedance of claim 1, wherein the microprocessor is further connected with a wireless communication module, the wireless communication module is connected with an external terminal, and the external terminal is used for recording and storing data and processing the data to obtain a data curve graph.
4. the device for measuring the extracellular fluid electrical impedance and the total moisture electrical impedance of claim 1, wherein the stimulation current frequency range is 20 ~ 300kHz, and the stimulation current magnitude is 0.3 ~ 3.0 mA.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109938728A (en) * | 2019-01-31 | 2019-06-28 | 苏州长脉科技有限责任公司 | The measuring device and method that a kind of resistanceper unit length of external fluid is anti-and total water sub-resistance is anti- |
| CN112957028A (en) * | 2021-04-09 | 2021-06-15 | 桂林电子科技大学 | Comprehensive abdominal health detection analyzer and analysis method thereof |
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2019
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109938728A (en) * | 2019-01-31 | 2019-06-28 | 苏州长脉科技有限责任公司 | The measuring device and method that a kind of resistanceper unit length of external fluid is anti-and total water sub-resistance is anti- |
| CN112957028A (en) * | 2021-04-09 | 2021-06-15 | 桂林电子科技大学 | Comprehensive abdominal health detection analyzer and analysis method thereof |
| CN112957028B (en) * | 2021-04-09 | 2023-04-07 | 桂林电子科技大学 | Comprehensive abdominal health detection analyzer and analysis method thereof |
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