CN209589916U - Electrochemical test piece - Google Patents
Electrochemical test piece Download PDFInfo
- Publication number
- CN209589916U CN209589916U CN201822143182.4U CN201822143182U CN209589916U CN 209589916 U CN209589916 U CN 209589916U CN 201822143182 U CN201822143182 U CN 201822143182U CN 209589916 U CN209589916 U CN 209589916U
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- electrode
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- electrode structure
- test piece
- insulating spacer
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- 238000000840 electrochemical analysis Methods 0.000 title description 3
- 238000006243 chemical reaction Methods 0.000 claims abstract description 93
- 238000012360 testing method Methods 0.000 claims abstract description 57
- 230000005518 electrochemistry Effects 0.000 claims abstract description 46
- 125000006850 spacer group Chemical group 0.000 claims abstract description 40
- 239000000758 substrate Substances 0.000 claims abstract description 17
- 230000005611 electricity Effects 0.000 claims description 8
- 238000009413 insulation Methods 0.000 abstract description 6
- 239000007788 liquid Substances 0.000 description 25
- 238000005259 measurement Methods 0.000 description 20
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- 239000004020 conductor Substances 0.000 description 9
- 238000000034 method Methods 0.000 description 9
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- 238000010586 diagram Methods 0.000 description 7
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- -1 polyethylene terephthalate Polymers 0.000 description 7
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 239000000463 material Substances 0.000 description 6
- WCUXLLCKKVVCTQ-UHFFFAOYSA-M Potassium chloride Chemical compound [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 5
- 229920002472 Starch Polymers 0.000 description 5
- 239000008107 starch Substances 0.000 description 5
- 235000019698 starch Nutrition 0.000 description 5
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 238000013461 design Methods 0.000 description 4
- FGIUAXJPYTZDNR-UHFFFAOYSA-N potassium nitrate Chemical compound [K+].[O-][N+]([O-])=O FGIUAXJPYTZDNR-UHFFFAOYSA-N 0.000 description 4
- NDVLTYZPCACLMA-UHFFFAOYSA-N silver oxide Chemical compound [O-2].[Ag+].[Ag+] NDVLTYZPCACLMA-UHFFFAOYSA-N 0.000 description 4
- 239000011734 sodium Substances 0.000 description 4
- 229910052708 sodium Inorganic materials 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
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- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 3
- 239000011149 active material Substances 0.000 description 3
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
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- 102000009027 Albumins Human genes 0.000 description 2
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- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
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- RGJOEKWQDUBAIZ-IBOSZNHHSA-N CoASH Chemical compound O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(O)(=O)OP(O)(=O)OCC(C)(C)[C@@H](O)C(=O)NCCC(=O)NCCS)O[C@H]1N1C2=NC=NC(N)=C2N=C1 RGJOEKWQDUBAIZ-IBOSZNHHSA-N 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- 229920002307 Dextran Polymers 0.000 description 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 2
- 229920000881 Modified starch Polymers 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000002202 Polyethylene glycol Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 239000004372 Polyvinyl alcohol Substances 0.000 description 2
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 description 2
- XJLXINKUBYWONI-DQQFMEOOSA-N [[(2r,3r,4r,5r)-5-(6-aminopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2s,3r,4s,5s)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate Chemical compound NC(=O)C1=CC=C[N+]([C@@H]2[C@H]([C@@H](O)[C@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](OP(O)(O)=O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 XJLXINKUBYWONI-DQQFMEOOSA-N 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- YBCVMFKXIKNREZ-UHFFFAOYSA-N acoh acetic acid Chemical compound CC(O)=O.CC(O)=O YBCVMFKXIKNREZ-UHFFFAOYSA-N 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 2
- 239000000920 calcium hydroxide Substances 0.000 description 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000001768 carboxy methyl cellulose Substances 0.000 description 2
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- 239000008112 carboxymethyl-cellulose Substances 0.000 description 2
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- RGJOEKWQDUBAIZ-UHFFFAOYSA-N coenzime A Natural products OC1C(OP(O)(O)=O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 RGJOEKWQDUBAIZ-UHFFFAOYSA-N 0.000 description 2
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 2
- 238000012937 correction Methods 0.000 description 2
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- KTWOOEGAPBSYNW-UHFFFAOYSA-N ferrocene Chemical compound [Fe+2].C=1C=C[CH-]C=1.C=1C=C[CH-]C=1 KTWOOEGAPBSYNW-UHFFFAOYSA-N 0.000 description 2
- 235000019162 flavin adenine dinucleotide Nutrition 0.000 description 2
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- 150000008040 ionic compounds Chemical class 0.000 description 2
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 description 2
- VTHJTEIRLNZDEV-UHFFFAOYSA-L magnesium dihydroxide Chemical compound [OH-].[OH-].[Mg+2] VTHJTEIRLNZDEV-UHFFFAOYSA-L 0.000 description 2
- 239000000347 magnesium hydroxide Substances 0.000 description 2
- 229910001862 magnesium hydroxide Inorganic materials 0.000 description 2
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- 239000004800 polyvinyl chloride Substances 0.000 description 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 description 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 2
- 239000001103 potassium chloride Substances 0.000 description 2
- 235000011164 potassium chloride Nutrition 0.000 description 2
- 235000012249 potassium ferrocyanide Nutrition 0.000 description 2
- 235000010333 potassium nitrate Nutrition 0.000 description 2
- 239000004323 potassium nitrate Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000003223 protective agent Substances 0.000 description 2
- 238000006722 reduction reaction Methods 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 229910052707 ruthenium Inorganic materials 0.000 description 2
- 238000007650 screen-printing Methods 0.000 description 2
- 229910001923 silver oxide Inorganic materials 0.000 description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 description 2
- 229910000029 sodium carbonate Inorganic materials 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 238000004528 spin coating Methods 0.000 description 2
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- 230000010148 water-pollination Effects 0.000 description 2
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 2
- 229960001763 zinc sulfate Drugs 0.000 description 2
- 229910000368 zinc sulfate Inorganic materials 0.000 description 2
- 125000001140 1,4-phenylene group Chemical group [H]C1=C([H])C([*:2])=C([H])C([H])=C1[*:1] 0.000 description 1
- 229920001342 Bakelite® Polymers 0.000 description 1
- 229910000906 Bronze Inorganic materials 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 229920002785 Croscarmellose sodium Polymers 0.000 description 1
- 229920000858 Cyclodextrin Polymers 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
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- 229920001503 Glucan Polymers 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 239000004366 Glucose oxidase Substances 0.000 description 1
- 108010015776 Glucose oxidase Proteins 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- BAWFJGJZGIEFAR-NNYOXOHSSA-N NAD zwitterion Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP([O-])(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-N 0.000 description 1
- BAWFJGJZGIEFAR-NNYOXOHSSA-O NAD(+) Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-O 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 1
- RRKGBEPNZRCDAP-UHFFFAOYSA-N [C].[Ag] Chemical compound [C].[Ag] RRKGBEPNZRCDAP-UHFFFAOYSA-N 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- KHTPCDDBDQRIRX-UHFFFAOYSA-N azane;hydrate Chemical compound N.[NH4+].[OH-] KHTPCDDBDQRIRX-UHFFFAOYSA-N 0.000 description 1
- 239000004637 bakelite Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 239000010974 bronze Substances 0.000 description 1
- 239000003990 capacitor Substances 0.000 description 1
- HFNQLYDPNAZRCH-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O.OC(O)=O HFNQLYDPNAZRCH-UHFFFAOYSA-N 0.000 description 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 1
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- 229920002678 cellulose Polymers 0.000 description 1
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- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 239000005516 coenzyme A Substances 0.000 description 1
- 229940093530 coenzyme a Drugs 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- KUNSUQLRTQLHQQ-UHFFFAOYSA-N copper tin Chemical compound [Cu].[Sn] KUNSUQLRTQLHQQ-UHFFFAOYSA-N 0.000 description 1
- 229910000366 copper(II) sulfate Inorganic materials 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 229960001681 croscarmellose sodium Drugs 0.000 description 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 description 1
- KDTSHFARGAKYJN-UHFFFAOYSA-N dephosphocoenzyme A Natural products OC1C(O)C(COP(O)(=O)OP(O)(=O)OCC(C)(C)C(O)C(=O)NCCC(=O)NCCS)OC1N1C2=NC=NC(N)=C2N=C1 KDTSHFARGAKYJN-UHFFFAOYSA-N 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000003487 electrochemical reaction Methods 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- 229920006335 epoxy glue Polymers 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 description 1
- VWWQXMAJTJZDQX-UYBVJOGSSA-N flavin adenine dinucleotide Chemical compound C1=NC2=C(N)N=CN=C2N1[C@@H]([C@H](O)[C@@H]1O)O[C@@H]1CO[P@](O)(=O)O[P@@](O)(=O)OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C2=NC(=O)NC(=O)C2=NC2=C1C=C(C)C(C)=C2 VWWQXMAJTJZDQX-UYBVJOGSSA-N 0.000 description 1
- 229940093632 flavin-adenine dinucleotide Drugs 0.000 description 1
- 150000002211 flavins Chemical class 0.000 description 1
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- 230000007274 generation of a signal involved in cell-cell signaling Effects 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229940116332 glucose oxidase Drugs 0.000 description 1
- 235000019420 glucose oxidase Nutrition 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000005534 hematocrit Methods 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 description 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 description 1
- 239000001341 hydroxy propyl starch Substances 0.000 description 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 1
- 235000013828 hydroxypropyl starch Nutrition 0.000 description 1
- 229960003943 hypromellose Drugs 0.000 description 1
- 238000013095 identification testing Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000000608 laser ablation Methods 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229950006238 nadide Drugs 0.000 description 1
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 1
- LFLZOWIFJOBEPN-UHFFFAOYSA-N nitrate, nitrate Chemical compound O[N+]([O-])=O.O[N+]([O-])=O LFLZOWIFJOBEPN-UHFFFAOYSA-N 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
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- 229920006389 polyphenyl polymer Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000000276 potassium ferrocyanide Substances 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 description 1
- CBXWGGFGZDVPNV-UHFFFAOYSA-N so4-so4 Chemical compound OS(O)(=O)=O.OS(O)(=O)=O CBXWGGFGZDVPNV-UHFFFAOYSA-N 0.000 description 1
- JVBXVOWTABLYPX-UHFFFAOYSA-L sodium dithionite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])=O JVBXVOWTABLYPX-UHFFFAOYSA-L 0.000 description 1
- XOGGUFAVLNCTRS-UHFFFAOYSA-N tetrapotassium;iron(2+);hexacyanide Chemical compound [K+].[K+].[K+].[K+].[Fe+2].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-].N#[C-] XOGGUFAVLNCTRS-UHFFFAOYSA-N 0.000 description 1
- AYEKOFBPNLCAJY-UHFFFAOYSA-O thiamine pyrophosphate Chemical compound CC1=C(CCOP(O)(=O)OP(O)(O)=O)SC=[N+]1CC1=CN=C(C)N=C1N AYEKOFBPNLCAJY-UHFFFAOYSA-O 0.000 description 1
- YXVCLPJQTZXJLH-UHFFFAOYSA-N thiamine(1+) diphosphate chloride Chemical compound [Cl-].CC1=C(CCOP(O)(=O)OP(O)(O)=O)SC=[N+]1CC1=CN=C(C)N=C1N YXVCLPJQTZXJLH-UHFFFAOYSA-N 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
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- 229940116269 uric acid Drugs 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model provides an electrochemistry test block, including insulating base plate, electrode system, first insulation spacer and the insulating spacer of second. The electrode system is disposed on the insulating substrate, wherein the electrode system includes a first electrode structure and a second electrode structure, and the first electrode structure and the second electrode structure are insulated from each other. A first insulating spacer covers a portion of the electrode system, wherein one end of the first insulating spacer has a recess and a portion of the electrode system is exposed to the recess. The second insulating spacer covers the first insulating spacer, wherein the recess of the first insulating spacer constitutes a reaction zone with the insulating substrate and the second insulating spacer, and the electrode system in the reaction zone has a disconnection region near the bottom of the recess. The utility model provides an electrochemistry test piece under the condition that does not need additionally to add other electrode structures, can accurately discern whether test sample reaches sufficient capacity and suitably covers the electrode.
Description
Technical field
The utility model relates to a kind of test piece more particularly to a kind of electrochemistry test pieces.
Background technique
The medicine of increasingly promotion with the progress and modern of to(for) health care idea, it is quick, cheap, small in size and
The self-checking product (for example, blood glucose meter, style electronic ear temperature gun and electronic sphygmomanometer etc.) for being not required to professional's operation more comes
More it attracts attention.In medicine or biochemistry detection, the use of electrochemistry test piece has been a universal technology.Existing electrification
Learning test piece, there are at least two measurements to use electrode (including a working electrode and a reference electrode), inject in liquid sample
After the reaction zone of test piece, the electric characteristics of sample are measured by the measuring electrode.However, such electrode design, nothing
Whether confirmatory sample has been completely covered the measuring electrode to method before measurements.
Currently, can in addition add third electrode in the reaction region, wherein compared to upper in commercially available electrochemistry test piece
Two measuring electrodes are stated, which is set to the least significant end that distance samples mouth is farthest in reaction zone.It, can after injecting sample
Pass through the nearest front end of distance samples mouth in third electrode detection reaction zone and two of the farthest least significant end of distance samples mouth
Curent change between measuring electrode, comes whether confirmatory sample suitably covers measuring electrode.Alternatively, it is also possible to set in the reaction region
Count at least four electrodes.That is, in addition adding third electrode and the 4th in the reaction region in addition to above-mentioned two measuring electrodes
Electrode, wherein compared to above-mentioned two measuring electrodes, third electrode and the 4th electrode are set in reaction zone distance samples mouth most
Remote least significant end.After sample enters reaction zone by capillary phenomenon, there is conductive capability using liquid sample and make third
Electrode and the 4th electrode electrically conduct, and then whether confirmatory sample covers measuring electrode.
However, measuring electrode whether is suitably covered for confirmatory sample, it is above-mentioned to add third electrode or add third electrode
Design with the 4th electrode all needs to increase the accommodating space of reaction zone.In addition, accurate to ensure that electrochemistry test piece reaches biochemical values
The effect of measurement need to add the measurement electricity of measurement interference factor (for example, uric acid, blood oxygen, haematocrit value etc.) in reaction zone
Pole for correcting measured value, also to need to increase the accommodating space of reaction zone, and then forces user that need to provide more Multi-example to anti-
It answers in area, this measure is against the trend for reducing offer sample volume now.
In addition, some commercially available electrochemistry test pieces at present are then to utilize measuring electrode test sample reaction amplitude or phase angle
Sample capacity is calculated, whether measuring electrode is covered with confirmatory sample.Though such mode is not required to additional electrode, however, by
Containing there are many substances with electric signal reaction to utilize above-mentioned detected amplitude during electrochemistry Concentration Testing in sample
Or the method at phase angle is easy to cause reaction zone electronics to be lost, and cause measurement of concetration error.Therefore, industry needs one kind and is not required to
Additional electrode can reduce electrode setting and can reach the electrochemistry test piece for accurately identifying sample capacity simultaneously.
Utility model content
The utility model provides a kind of electrochemistry test piece, under conditions of being not required to other electrode structures of additional
Accurately whether identification test sample reaches enough capacity and suitably covers electrode.
The electrochemistry test piece of the utility model, including insulating substrate, electrode system, the first insulating spacer and the second insulation
Partition.Electrode system is configured on insulating substrate, and wherein electrode system includes first electrode structure and second electrode structure, and
One electrode structure and the setting insulated from each other of second electrode structure.The electrode system of first insulating spacer covering part, wherein first
One end of insulating spacer has recess, and the electrode system of part is exposed to recess.Second insulating spacer covers the first insulating spacer,
Wherein the recess of the first insulating spacer and insulating substrate and the second insulating spacer constitute reaction zone, wherein electricity in the reaction region
Electrode systems have breaking area close to notched bottoms.
In an embodiment of the utility model, above-mentioned breaking area is located at first electrode structure.
In an embodiment of the utility model, above-mentioned first electrode structure includes preceding electrode segment and rear electrode district
Section.Preceding electrode segment includes the section that first electrode structure extends to breaking area from close pocket top.Electrode segment includes afterwards
First electrode structure self-blocking area extends close to the section of notched bottoms.Open circuit between preceding electrode segment and rear electrode segment
The distance in area is first distance, and electrically distance is second distance to the minimum between preceding electrode segment and second electrode structure, rear electricity
Electrically distance is third distance to minimum between polar region section and second electrode structure, and wherein third distance is greater than first distance, the
Three distances are greater than second distance.
In an embodiment of the utility model, above-mentioned third distance be greater than or equal to first distance and second distance it
With.
In an embodiment of the utility model, above-mentioned first distance is greater than second distance.
In an embodiment of the utility model, above-mentioned first distance is greater than or equal to twice of second distance.
In an embodiment of the utility model, above-mentioned first electrode structure is reference electrode, and second electrode structure is
Working electrode.
In an embodiment of the utility model, above-mentioned first electrode structure is working electrode, and second electrode structure is
Reference electrode.
In an embodiment of the utility model, the second above-mentioned insulating spacer includes venthole, and venthole is in insulation
Projection on substrate is located in reaction zone, and wherein venthole partly overlaps with breaking area in the projection on electrode system or weighs completely
It is folded.
In an embodiment of the utility model, above-mentioned breaking area includes conductive layer.
Based on above-mentioned, the utility model is designed by the breaking area of the first electrode structure in electrochemical test on piece, not
Under conditions of needing other electrode structures of additional, it can accurately identify whether test sample reaches enough capacity and appropriate
Ground covers electrode.That is, the electrochemistry test piece of the utility model is empty in the accommodating for being not required to increase electrochemistry test piece reaction zone
Between under conditions of, user is not required to provide more test samples, can be effectively reduced the probability of test crash, and after ensuring
The accuracy of continuous measured value.
In order to make the above-mentioned features and advantages of the utility model more obvious and understandable, special embodiment below, and cooperate attached drawing
It is described in detail below.
Detailed description of the invention
Fig. 1 is a kind of structural exploded view of electrochemistry test piece of an embodiment of the present invention；
Fig. 2 is the partial perspective schematic view of the electrochemistry test piece of Fig. 1；
Fig. 3 is the block schematic diagram that the electrochemistry test piece of Fig. 1 is connect with bio-measurement instrument；
Fig. 4 A is the perspective diagram of the electrochemistry test piece of an embodiment of the present invention；
Fig. 4 B is the perspective diagram of the electrochemistry test piece of another embodiment of the utility model.
Specific embodiment
Fig. 1 is a kind of structural exploded view of electrochemistry test piece of an embodiment of the present invention, wherein understanding for convenience
The relative position of each interelement represents the position profile of this electrochemistry test piece with dotted line.Fig. 2 is the office of the electrochemistry test piece of Fig. 1
Portion's perspective diagram.
Referring to Fig.1 and 2, the electrochemistry test piece 100 of the utility model include insulating substrate 110, electrode system 120,
First insulating spacer 130 and the second insulating spacer 150.In some embodiments, insulating substrate 110 has electrical insulating property,
Material can be for example including polyvinyl chloride (PVC), glass fibre, polyester, bakelite plate, polyethylene terephthalate (PET), poly- carbon
Acid esters (PC), polypropylene (PP), polyethylene (PE), polystyrene (PS), ceramics or combinations thereof, but the utility model is not limited to
This.
Electrode system 120 is configured on insulating substrate 110, wherein electrode system 120 include first electrode structure 122 and
Second electrode structure 124, first electrode structure 122 and the setting insulated from each other of second electrode structure 124.In some embodiments,
First electrode structure 122 is, for example, reference electrode, and second electrode structure 124 is, for example, working electrode, 122 He of first electrode structure
Second electrode structure 124 forms a measuring electrode group, but the utility model is without being limited thereto.In other embodiments, electrode system
120 may include other electrodes, such as correcting electrode, functional electrode etc..In some embodiments, the material of electrode system 120 can
For example, any conductive materials, such as carbon paste, elargol, copper glue, carbon silver epoxy glue or its analog and combination etc., but this is practical new
Type is without being limited thereto.
The electrode system 120 of first insulating spacer, 130 covering part, wherein one end of the first insulating spacer 130 is with recessed
Mouth 132, the electrode system 120 of part is exposed to recess 132.In some embodiments, the first insulating spacer 130 covering part
Electrode system 120 makes the first electrode structure 122 of part and partial second electrode structure 124 be exposed to recess 132.One
In a little embodiments, the material of the first insulating spacer 130 can be exhausted for example including PVC insulating tape, PET insulating tape, heated drying type
Edge paint or ultraviolet light drying type insulated paint, but the utility model is without being limited thereto.
Second insulating spacer 150 covers the first insulating spacer 130, wherein the recess 132 of the first insulating spacer 130 and insulation
Substrate 110 and the second insulating spacer 150 constitute reaction zone 140, and reaction zone 140 can be used to accommodate liquid sample, reaction zone
140 have thief hatch 141, and thief hatch 141 is close to the top of recess 132, for liquid sample injection.When liquid sample is reflexive
After answering the thief hatch 141 in area 140 to inject, each electrode in electrode system can be sequentially contacted.In some embodiments, electrode system
120 are united close to thief hatch 141 and the one end not covered by the first insulating spacer 130 is located in reaction zone 140, and electrode system
120 other ends far from thief hatch 141 are then used to be connected with measuring instrument 10 (as shown in Figure 3).
In some embodiments, transparent or semitransparent material for example can be selected in the material of the second insulating spacer 150, with side
Just whether observing response area 140 has inserted sample, avoids being detected in the case where sample is not inserted, and leads to mistake
Measurement result, but the utility model is without being limited thereto.In further embodiments, the second insulating spacer 150 can be for example including transparent
The area of observation coverage 152, and the transparent area of observation coverage 152 partly overlaps or completely overlapped in the projection on insulating substrate 110 with reaction zone 140,
Thus it is designed to facilitate whether observing response area 140 has inserted sample.In some embodiments, the second insulating spacer 150 exists
Surface 150a close to reaction zone 140 can be coated with a hydrophily partition, to reinforce the capillarity of 140 inside wall surface of reaction zone,
It more quickly and efficiently will be in Sample introduction reaction zone 140.In some embodiments, the second insulating spacer 150 includes venthole
154, venthole 154 is arranged corresponding to recess 132, and the setting of venthole 154 can reinforce capillarity, reaction zone 140 is discharged
Interior gas.In some embodiments, venthole 154 is located in reaction zone 140 in the projection on insulating substrate 110.Another
In a little embodiments, venthole 154 is disposed in proximity to the bottom of recess 132, but the utility model is without being limited thereto.In the utility model
In, it is not intended to limit the shape of venthole 154, for example, the shape of venthole 154 may be, for example, round, ellipse, rectangle
Or diamond shape etc., but the utility model is without being limited thereto.
In some embodiments, electrochemistry test piece can for example be set for example including recognition unit (not shown), recognition unit
It is placed in the connection side that the upper surface electrode system of the second insulating spacer 150 connects with measuring instrument.In further embodiments, know
Other unit, which also may, for example, be, is set to one end that 110 upper electrode system 120 of substrate is relatively distant from thief hatch 141, and identifies single
Member is not interfere with each other each other with electrode system 120.In some embodiments, recognition unit can be for example including multiple electrical property
Element.Electrical components can be various conductive electrical components, for example, electrical property of the electrical property feature with passive device
Element.In some embodiments, electrical components may be, for example, resistance, and the material of electrical components for example can be with 120 phase of electrode system
Together, the forming method of electrical components may be, for example, wire mark (screen printing), coining (imprinting), thermal transfer
(thermal transfer printing), method of spin coating (spin coating), ink jet printing (ink-jet
Printing), laser stripping plating (laser ablation), deposition (deposition), plating (electrodeposition),
The technologies such as wire mark (screen-printing).However, in further embodiments, the electrical components that recognition unit includes can example
For example resistance, capacitor, inductance, integrated circuit and/or its combination, but the utility model is without being limited thereto.When electrochemistry test piece is placed in
When measuring instrument, measuring instrument can detect that position and the quantity of each electrical components on recognition unit, through distinguishing electrochemistry therefrom
The type of test piece, and then adopt corresponding correction parameter or mode measures.In other words, the quantity of this multiple electrical components and
Position determines the identification code of electrochemistry test piece, makes measuring instrument that can distinguish electrochemistry test piece accordingly.However, the utility model is not
Limit quantity, the shapes or configure mode of electrical components included by recognition unit.In addition, the utility model is not intended to limit identification
The setting position of unit or working method, as long as recognition unit can allow measuring instrument to read identification code.
In some embodiments, the electrochemistry test piece of the utility model further includes conversion zone 142, wherein conversion zone 142
In in reaction zone 140 and the first electrode structure 122 of at least covering part.Conversion zone 142 be, for example, be used for and liquid sample into
Row electrochemical reaction or generation specificity distinguish bio signal.In some embodiments, conversion zone 142 is at least covered in reaction
On electrode position in area 140, can also it be covered on the non-electrode position in reaction zone 140, to be electrochemically reacted
Or it generates specificity and distinguishes bio signal.Conversion zone 142 can at least cover the first electrode structure of the part of reaction zone 140
122 with the second electrode structure 124 of part, and be limited with not blocking thief hatch.In general, the area of conversion zone 142 is small
In the area of reaction zone 140, as long as conversion zone 142 can be chemically reacted with liquid sample, the utility model is to its shape
Shape is not limited.
In some embodiments, conversion zone 142 is for example including conducting medium, active material, buffer, protective agent or its group
It closes, but the utility model is without being limited thereto.In some embodiments, conducting medium for example can be used for receiving sample (for example, blood,
Urine, saliva etc.) generated electronics after reaction, and the electronics is conducted via electrode system 120 to bio-measurement instrument.One
In a little embodiments, conducting medium can be for example including potassium ferricyanide (potassium ferricyanide), potassium ferrocyanide (potassium
Hexacyanoferrate (II) trihydrate), ruthenium (ruthenium, RU), ferrocene (ferrocene), hydrosulfurous acid
Sodium (sodium dithionite), Nicotinic Acid Amide adenine-dinucleotide (nicotinamide adenine
Dinucleotide, NAD+), Nicotinic Acid Amide adenine-dinucleotide phosphoric acid (nicotinamide adenine
Dinucleotide phosphate NADP+), b1thiaminpyrophosphate (thiamin pyrophosphate, TPP), coacetylase
(coenzyme A, HSCoA), flavin nucleotide (flavin adenine dinucleotide, FAD) or combinations thereof.Some
In embodiment, active material for example refers to including the ferment (for example, glucose oxidase), anti-through immobilization or unlockedization
Original, antibody, microbial cell, animal and plant cells, animal vegetable tissue or combinations thereof are also possible to other with biological identification energy
The ingredient of power.In some embodiments, buffer is, for example, phosphate buffer.In some embodiments, protective agent for example wraps
Albumen, dextrin, dextran, Amino acid or combinations thereof are included, but the utility model is without being limited thereto.
Referring to figure 2., in the present embodiment, first electrode structure 122 and second electrode knot are provided in reaction zone 140
Structure 124, wherein first electrode structure 122 is, for example, reference electrode, and second electrode structure 124 is, for example, working electrode, real below
Applying example will be explained with this, but the utility model is without being limited thereto.That is, in other embodiments, first electrode structure 122
Also it may, for example, be working electrode, second electrode structure 124 is, for example, reference electrode.In measurement process, 10 pairs of electricity of measuring instrument
Interpolar applies a voltage difference and the sample in reaction zone 140 is promoted to be chemically reacted and converted chemical energy into conversion zone 142
Electric energy, then concentration analysis is carried out by measuring instrument 10.However, the utility model is not intended to limit the configuration of electrode.In general, only
Each electrode such as above-mentioned effect is configured in electrode system 120, and between each electrode contact with liquid sample it is preceding each other
Insulation, and it is i.e. real enough a conductive loops to be formed between measuring instrument 10 after electrode system 120 and liquid sample contact
It applies.
In the present invention, the electrode system 120 in reaction zone 140 has breaking area 125 close to 132 bottom of recess.
In some embodiments, the first electrode structure 122 in reaction zone 140 has breaking area 125 close to 132 bottom of recess, also
It is to say, breaking area 125 is, for example, to be located at first electrode structure 122, but the utility model is without being limited thereto.Specifically, the first electricity
Pole structure 122 includes preceding electrode segment 122a and rear electrode segment 122b, wherein preceding electrode segment 122a includes first electrode
For structure 122 from the section for extending to breaking area 125 at the top of recess 132, rear electrode segment 122b includes first electrode structure
122 self-blocking areas 125 extend close to the section of 132 bottom of recess.That is, by the design in breaking area 125, by first
Electrode structure 122 divides for preceding electrode segment 122a and rear bis- section of electrode segment 122b, when the unfilled reaction zone of liquid sample
140 and before covering breaking area 125, preceding electrode segment 122a be closer to reaction zone 140 thief hatch 141 and with measuring instrument 10
The section of insulation, then electrode segment 122b is then the section linked with measuring instrument 10.When liquid sample fills up reaction zone 140
And when covering the preceding electrode segment 122a and rear electrode segment 122b of first electrode structure 122, liquid sample will make the second electricity
Pole structure 124, the preceding electrode segment 122a of first electrode structure 122 and rear electrode segment 122b are simultaneously turned on.Further, since
Breaking area 125 is set to reaction zone 140 close to the bottom of recess 132, therefore can determine whether liquid sample has covered entire reaction
Area 140.For example, the method inspected may be, for example, power-up after second electrode structure 124 and first electrode structure 122
Between electrode segment 122b, and observes it and electrically change.Under normal circumstances, the preceding electrode segment of first electrode structure 122
122a and rear electrode segment 122b is not before its breaking area 125 is completely covered for liquid sample, first electrode structure 122 and second
Electrode structure 124 can not also be connected, therefore can then inspect the electrical variation of first electrode structure 122 and second electrode structure 124,
Whether it is covered with reaction zone 140 close to the bottom of recess 132 with judgement sample and covers second electrode structure 124.It is worth mentioning
It is that the utility model is not intended to limit the setting position in breaking area 125, it is only necessary to be located at reaction zone 140 compared to other electrodes and relatively lean on
It the bottom (least significant end) of nearly recess 132 and can be covered by sample.In a preferred embodiment, breaking area 125 can for example be set
It is placed in 154 lower section of venthole, in other words, venthole 154 partly overlaps in the projection on electrode system 120 with breaking area 125
Or it is completely overlapped.In one embodiment, when breaking area 125 is located at first electrode structure 122, venthole 154 is in first
Projection on electrode structure 122 partly overlaps or completely overlapped with breaking area 125.In one more preferably embodiment, breaking area 125 1
Fraction is covered by the first insulating spacer 130, but the utility model is without being limited thereto.
After confirmatory sample suitably covers reaction zone 140, first electrode structure 122 and second electrode knot can be carried out
Electrical measurement between structure 124, mainly oxidoreducing enzyme of the measurement in reaction zone 140 in sample and conversion zone 142 into
Row electrochemical action and the curent change generated, through thus curent change analysis of biochemical meaning concentration value.It is noted that this
Utility model is not intended to limit the measuring process.In some embodiments, measuring instrument 10 confirms first electrode structure 122 and the second electricity
Pole structure 124 can first power off and stand specific time after being connected, then receive reaction electronics through second electrode structure 124.In
In other embodiments, after measuring instrument 10 confirms that first electrode structure 122 and second electrode structure 124 are connected, it can also carry out immediately
Measurement of concetration program.
In typical circumstances, second electrode structure 124 is the electrode that oxidation reaction occurs with sample and conversion zone 142, and
First electrode structure 122 is the electrode that reduction reaction occurs with sample and conversion zone 142, theoretically second electrode structure 124 with
122 impedance of first electrode structure is necessary for known fixed value.However, big in the reducing power for ensuring first electrode structure 122
In the case where the redox ability of 142 active material of conversion zone and sample, 122 impedance of first electrode structure is tolerable to be existed
A certain range internal impedance difference, and the resistance difference will not influence measurement of concetration accuracy.Therefore each liquid sample impedance contrast
Although the different reduction reaction effect that will cause first electrode structure 122, the measurement of concetration for having no effect on the utility model are accurate
Degree.
In the present embodiment, preceding electrode segment 122a is the at a distance from the breaking area 125 between rear electrode segment 122b
One distance D1, electrically distance is second distance D2, rear electrode to the minimum between preceding electrode segment 122a and second electrode structure 124
Electrically distance is third distance D3 to minimum between section 122b and second electrode structure 124.Specifically, according to Kirchhoff
Current law (Kirchhoff's current law, KCL), after liquid sample is fully filled with reaction zone 140, liquid can be gone here and there
The preceding electrode segment 122a and rear electrode segment 122b of logical first electrode structure 122.In some embodiments, third distance D3
It is greater than second distance D2 greater than first distance D1, third distance D3.In further embodiments, third distance D3 is greater than or equal to
The sum of first distance D1 and second distance D2, but the utility model is without being limited thereto.In a preferred embodiment, first distance D1 is big
In second distance D2, to ensure that the preceding electrode segment 122a of first electrode structure 122 can play optimum efficiency.More preferably implement one
In example, first distance D1 is greater than or equal to twice of second distance D2, but the utility model is without being limited thereto.However, this is practical new
Type is not particularly limited the proportionate relationship between first distance D1, second distance D2 and third distance D3, as long as first electrode
Structure 122 can reach simultaneously to be had both measurement concentration and confirms that liquid sample is fully filled with the function of reaction zone 140.
It is noted that in some cases, because the liquid sample that user injects reaction zone 140 is insufficient, leading to liquid
When aspect product fail to be fully filled with reaction zone 140, but make liquid sample because of the hydrophily of reaction zone 140 and capillary phenomenon effect
The rear electrode segment 122b of second electrode structure 124 and first electrode structure 122 is only covered, and not by first electrode structure
Preceding electrode segment 122a and rear electrode segment 122b link；Or in other cases, sample only covers first electrode structure
122 breaking area 125 and second electrode structure 124, and do not cover first electrode structure 122 close to thief hatch 141 section.
In this two kinds of insufficient situations of sample, since conversion zone 142 can dissolve not exclusively, reaction signal will be less than normal range (NR) threshold
Value, therefore measuring instrument 10 only needs after checking whether first electrode structure 122 and second electrode structure 124 are connected, then judges reaction letter
Number threshold value is it can be learnt that whether sample is covered with reaction zone 140 completely.Furthermore due to the first electrode structure 122 of the utility model
Have the design in breaking area 125 close to 132 bottom of recess in reaction zone 140, therefore, signal threshold value under normal circumstances, can recognize
Determine liquid sample and is covered with reaction zone 140 completely.
In some embodiments, the utility model can be for example including conduction in the breaking area 125 of first electrode structure 122
Layer, for example, conductive layer can be for example including conductive materials, curing agent or combinations thereof, but the utility model is without being limited thereto.One
As in the case of, conductive layer is solid-state like before contacting with sample, and the impedance of conductive layer can then change after contacting with sample
Become.
In some embodiments, conductive materials can be used for increasing the preceding electrode segment that liquid gangs up first electrode structure 122
Effect between 122a and rear electrode segment 122b.In some embodiments, conductive materials are, for example, dry, can for example be wrapped
Ionic compound, conductive metal, conjugated double bond polymers or combinations thereof are included, but the utility model is without being limited thereto.In some implementations
In example, ionic compound is for example including acetic acid (acetic acid) polymer, acetic acid (ethanoic acid) polymer, chlorine
It is poly- to change hydrogen (hydrogen chloride) polymer, sulfuric acid (sulfuric acid) polymer, nitric acid (nitric acid)
Close object, carbonic acid (carbonic acid) polymer, sodium bicarbonate (sodium bicarbonate) polymer, calcium hydroxide
(calcium hydroxide) polymer, sodium hydroxide (sodium hydroxide) polymer, ammonium hydroxide (ammonia) polymerization
Object, magnesium hydroxide (magnesium hydroxide) polymer, sodium carbonate (sodium carbonate) polymer, sodium chloride
(sodium chloride) polymer, potassium nitrate (potassium nitrate) polymer, copper sulphate (copper (II)
Sulfate) polymer, zinc sulfate (zinc sulfate) polymer, potassium chloride (potassium chloride) polymer or
A combination thereof.In some embodiments, conductive metal is for example including bronze, silver powder, copper powder, platinum powder, iron powder or combinations thereof.Some
In embodiment, conjugated double bond polymers are for example including polyaniline (polyaniline), polyacetylene (polyacetylene), polyphenyl
Acetylene (polyphenylvinylene) gathers to benzene (poly-p-phenylene), polypyrrole (polypyrrole), polythiophene
(polythiophene) or combinations thereof, but the utility model is without being limited thereto.In some embodiments, conductive materials can also example
Silver oxide (silver oxide) in this way.
In some embodiments, curing agent can be used for ensuring that conductive materials do not influence conductive effect because of liquid sample dissolution
Fruit.In some embodiments, curing agent is for example including natural polymer, synthetic polymer or combinations thereof.In some embodiments,
Natural polymer is for example including fibre-forming polymer, gelatinized corn starch (starch paste), glucan (dextran), albumin
(albumin) or combinations thereof.Fibre-forming polymer is for example including hypromellose (hydroxypropyl methyl
Cellulose, HPMC), hydroxypropyl cellulose (hydroxypropyl cellulose, HPC), hydroxyethyl cellulose
(hydroxyethyl cellulose, HEC), microcrystalline cellulose (microcrystalline cellulose, MCC).Starch
Paste is for example including dextrin (dextrin), cyclodextrin, pre-gelatinized starch (pregelatinized starch), sodium carboxymethyl starch
(carboxymethyl starch sodium), hydroxypropyl starch (hydroxypropy starch), carboxymethyl cellulose
(carboxy methyl cellulose), croscarmellose sodium (crosslinked carboxymethy
Cellulose sodium), low-substituted hydroxypropyl cellulose (low substituted hydroxypropyl cellulose).
In some embodiments, synthetic polymer is for example including polyvinylpyrrolidone (PVP), polyethylene glycol (PEG), polyvinyl alcohol
(PVA) or combinations thereof, but the utility model is without being limited thereto.
It is worth noting that, the utility model is not intended to limit the conduction for being set to the breaking area 125 of first electrode structure 122
Ingredient relationship between substance and conversion zone 142, as long as conductive materials will not influence conversion zone 142 and sample carries out electrochemistry
Reaction.In some embodiments, the conductive materials for being set to the breaking area 125 of first electrode structure 122 can be with conversion zone
142 are of identical composition.In other embodiments, the conductive materials for being set to the breaking area 125 of first electrode structure 122 can be with
There is different ingredients from conversion zone 142.
Fig. 3 is the block schematic diagram that the electrochemistry test piece of Fig. 1 is connect with bio-measurement instrument.Referring to figure 2. and Fig. 3, electrode
System 120 has the electrode system 120 of part exposed far from one end of reaction zone 140 (or thief hatch 141), is for electrically connecting
It is connected to measuring instrument 10, to form conductive loops between measuring instrument 10.In some embodiments, measuring instrument 10 includes connector
11, computing unit 12, analog-digital converter (analog to digital converter, ADC) 13, processor 14, display
Device 15 and power supply unit 16, wherein connector 11 is for external connection, and computing unit 12 is for converted score.In a tool
In body embodiment, after sample enters reaction zone 140 of electrochemistry test piece 100, sample can be covered on the electrode system of part
On 120.When the power supply unit 16 of measuring instrument 10 applies electric signal to electrode system 120, sample is corresponding with electric signal generation
Reaction signal and the computing unit 12 that measuring instrument 10 is transmitted to by connector 11.Then, by computing unit 12 by the reaction
Signal is converted, and analog-digital converter 13 is output to, to obtain digitized reaction signal, this digitized reaction signal
Via processor 14 to be further processed and/or show measurement result via display 15.
Fig. 4 A is the perspective diagram of the electrochemistry test piece of an embodiment of the present invention.Fig. 4 B is that the utility model is another
The perspective diagram of the electrochemistry test piece of embodiment.In Figure 4 A, electrode system 120 is pectination fourchette electrode, first electrode
Structure 122 forms breaking area 125 in the least significant end of reaction zone 140, is thus detected the feelings that liquid sample fills up reaction zone 140
Condition.In figure 4b, electrode system 120 in addition to include above-mentioned measurement concentration (the first electrode structure 122/ the of concentration electrode 121
Two electrode structures 124) outside, in addition the correcting electrode 126 of correction and the functional electrode 128 of non-measurement of concetration can be set.Value
If it is noted that each electrode structure putting in order in reaction zone 140 or be arranged as described above, and each electrode structure it
Between it is insulated from each other, the utility model is not intended to limit set-up mode and reaction zone of each electrode structure in biological test paper 100
140 shape.
In conclusion the utility model is designed by the breaking area of the first electrode structure in electrochemical test on piece, not
Under conditions of needing other electrode structures of additional, it can accurately identify whether test sample reaches enough capacity and appropriate
Ground covers electrode.That is, the electrochemistry test piece of the utility model is empty in the accommodating for being not required to increase electrochemistry test piece reaction zone
Between under conditions of, user is not required to provide more test samples, can be effectively reduced the probability of test crash, and after ensuring
The accuracy of continuous measured value.
Although the utility model is disclosed as above with embodiment, so it is not intended to limit the utility model, any affiliated
Technical staff in technical field, without departing from the spirit and scope of the utility model, when can make a little change and retouching, therefore
Subject to the protection scope of the utility model ought be defined depending on claim.
Claims (10)
1. a kind of electrochemistry test piece characterized by comprising
Insulating substrate；
Electrode system is configured on the insulating substrate, wherein the electrode system includes first electrode structure and the second electricity
Pole structure, the first electrode structure and the second electrode structure setting insulated from each other；
First insulating spacer, the electrode system of covering part, wherein one end of first insulating spacer has recess, portion
The electrode system divided is exposed to the recess；And
Second insulating spacer covers first insulating spacer, wherein the recess of first insulating spacer and it is described absolutely
Edge substrate and second insulating spacer constitute reaction zone, wherein the electrode system in the reaction zone is close to described
Notched bottoms have breaking area.
2. electrochemistry test piece according to claim 1, which is characterized in that the open circuit area is located at the first electrode knot
Structure.
3. electrochemistry test piece according to claim 2, which is characterized in that the first electrode structure includes:
Preceding electrode segment extends to the section in the breaking area including the first electrode structure from the close pocket top；
And
Electrode segment afterwards extends close to the section of the notched bottoms including the first electrode structure from the breaking area,
Wherein the preceding electrode segment is first distance at a distance from the breaking area between the rear electrode segment, before described
Electrically distance is second distance to minimum between electrode segment and the second electrode structure, it is described after electrode segment and described the
Electrically distance is third distance to minimum between two electrode structures, wherein third distance is greater than the first distance, it is described
Third distance is greater than the second distance.
4. electrochemistry test piece according to claim 3, which is characterized in that the third distance is greater than or equal to described first
The sum of distance and the second distance.
5. electrochemistry test piece according to claim 3, which is characterized in that the first distance is greater than the second distance.
6. electrochemistry test piece according to claim 5, which is characterized in that the first distance is greater than or equal to twice of institute
State second distance.
7. electrochemistry test piece according to claim 2, which is characterized in that the first electrode structure is reference electrode, institute
Stating second electrode structure is working electrode.
8. electrochemistry test piece according to claim 2, which is characterized in that the first electrode structure is working electrode, institute
Stating second electrode structure is reference electrode.
9. electrochemistry test piece according to claim 1, which is characterized in that second insulating spacer includes venthole, and
The venthole is located in the reaction zone in the projection on the insulating substrate, wherein the venthole is in the electrode system
On projection partly overlap with the breaking area or completely overlapped.
10. electrochemistry test piece according to claim 1, which is characterized in that the open circuit area includes conductive layer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TW107215212U TWM574235U (en) | 2018-11-08 | 2018-11-08 | Electrochemical test sheet |
| TW107215212 | 2018-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209589916U true CN209589916U (en) | 2019-11-05 |
Family
ID=66214985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201822143182.4U Active CN209589916U (en) | 2018-11-08 | 2018-12-20 | Electrochemical test piece |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN209589916U (en) |
| TW (1) | TWM574235U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114544733A (en) * | 2020-11-25 | 2022-05-27 | 五鼎生物技术股份有限公司 | Biochemical test piece |
-
2018
- 2018-11-08 TW TW107215212U patent/TWM574235U/en unknown
- 2018-12-20 CN CN201822143182.4U patent/CN209589916U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114544733A (en) * | 2020-11-25 | 2022-05-27 | 五鼎生物技术股份有限公司 | Biochemical test piece |
| CN114544733B (en) * | 2020-11-25 | 2024-06-11 | 五鼎生物技术股份有限公司 | Biochemical test piece |
Also Published As
| Publication number | Publication date |
|---|---|
| TWM574235U (en) | 2019-02-11 |
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