CN209555194U - A kind of eight concussion instruments SNP grouping reagents device - Google Patents

Abstract

The utility model discloses a kind of eight concussion instrument SNP grouping reagents devices, including firm banking, the first spring of several groups is fixedly installed on the upper surface of the firm banking, the upper end of first spring is connected with fixed plate, the first fixed column is fixedly installed in the two sides of the first both ends of the spring on the upper surface of the firm banking, the upper end of first fixed column is provided with the second fixed column, the upper end of second fixed column is fixed on the lower surface of fixed plate, the lower end of second fixed column is threaded with adjusting rod by opening up internal screw thread, the two sides of the fixed plate upper surface are respectively set fixed block and are fixedly installed the first installing frame and the second installing frame, several groups second spring is fixedly installed on the inner sidewall of first installing frame two sides.The utility model structure is simple, and design rationally, can adjust vibration frequency, the mixed effect of reagent is more preferable, can detect the gene of multiple groups difference cell simultaneously, and detection effect is more preferable according to actual needs.

Description

A kind of eight concussion instruments SNP grouping reagents device

Technical field

The utility model relates to SNP grouping reagents equipment technical field, specially a kind of eight concussion instruments are tried with SNP parting Agent device.

Background technique

SNP research is the important step that the Human Genome Project moves towards application, this, which is primarily due to SNP, will provide one by force Strong tool, for the discovery of high risk group, the identification of disease related gene, the design of drug and test and biology Basic research etc., SNP are distributed quite extensively, research shows that every 300 base-pair occurs as soon as in human genome in genome Once, a large amount of existing SNP sites make people have an opportunity discovery and various diseases, including the relevant genome mutation of tumour, from From the point of view of experimental implementation, by SNP find disease-correlative gene mutation than by family come it is easy, some SNP are not direct Lead to the expression of disease gene, but since it is adjacent with certain disease genes, and become important label, SNP is in basic research In also played huge effect.

Conventional apparatus has following deficiency:

1, hybrid by the progress of eight concussion instruments, although the concussion power adjustable of eight concussion instruments, concussion effect Power can not be controlled effectively after being transmitted on reagent device, may affect the mixing of reagent to a certain extent；

2, it when carrying out SNP detection, needs to detect the gene of different location cell under same state, due to same One cytogene needs to detect multiple groups, can not carry out effective comparative experiments.

Utility model content

The purpose of this utility model is to provide a kind of eight concussion instruments SNP grouping reagents devices, to solve above-mentioned back Being carried out by eight concussion instruments for proposing in scape technology is hybrid, although the concussion power adjustable of eight concussion instruments, concussion Active force can not be controlled effectively after being transmitted on reagent device, may affect the mixing of reagent to a certain extent Problem.

To achieve the above object, the utility model provides the following technical solutions: a kind of eight concussion instrument SNP grouping reagents Device, including firm banking are fixedly installed the first spring of several groups, first spring on the upper surface of the firm banking Upper end be connected with fixed plate, be fixedly installed first in the two sides of the first both ends of the spring on the upper surface of the firm banking Fixed column, the upper end of first fixed column are provided with the second fixed column, and the upper end of second fixed column is fixed at On the lower surface of fixed board, the lower end of second fixed column is threaded with adjusting rod, the fixed plate by opening up internal screw thread The two sides of upper surface are respectively set fixed block and are fixedly installed the first installing frame and the second installing frame, first installing frame two sides Inner sidewall on be fixedly installed several groups second spring, the other end of the second spring is fixedly installed first clamping plate, First agent plate is installed between first installing frame and first clamping plate, it is solid on the inner sidewall of second installing frame two sides Surely it is provided with several groups third spring, the other end of the third spring is fixedly installed second clamping plate, second installing frame Second agent plate is installed between second clamping plate, is fixedly installed on the upper surface of first agent plate and the second agent plate There are several Reagent Tubes.

Preferably, the upper end of first fixed column offers the threaded hole to match with adjusting rod, the adjusting rod Length is longer than the distance between the first fixed column and the second fixed column, is fixedly installed adjusting block on the adjusting rod.

Preferably, at least six groups of the quantity of first spring, second spring and third spring.

Preferably, it is provided with sliding slot on first installing frame and the inner sidewall of the second installing frame two sides, described first The two sides of clamping plate and second clamping plate are provided with sliding block, and the sliding slot is slidably connected with sliding block.

Preferably, first installing frame and the second installing frame are provided with first baffle in the lower end of sliding slot, and described Second baffle is provided on one clamping plate and second clamping plate, the first baffle and second baffle are in same level.

Preferably, the diameter of the Reagent Tube upper end tube nozzle is smaller than the diameter of Reagent Tube pipe shaft.

Compared with prior art, the utility model has the beneficial effects that

1, for the utility model by being fixedly installed the first spring of several groups on the upper surface of firm banking, second is fixed The lower end surface of column is threaded with adjusting rod by opening up threaded hole, by adjust between adjusting rod and the first fixed column away from From vibration frequency can be adjusted according to actual needs, and the mixed effect of reagent is more preferable；

2, the utility model in fixed plate by being fixedly installed the first installing frame and the second installing frame, the first installing frame With the first agent plate and the second agent plate are separately installed on the second installing frame, can by the first agent plate and the second agent plate To detect the gene of multiple groups difference cell simultaneously, detection effect is more preferable.

Detailed description of the invention

Fig. 1 is a kind of eight concussion instruments SNP grouping reagents device entirety main view of the utility model；

Fig. 2 is a kind of eight concussion instruments SNP grouping reagents device overall top view of the utility model；

Fig. 3 is that a kind of eight concussion instruments the first installing frame of SNP grouping reagents device of the utility model and first clamping plate connect Connect schematic diagram.

In figure: 1, firm banking；2, the first spring；3, fixed plate；31, fixed block；4, the first fixed column；5, second is fixed Column；6, adjusting rod；61, adjusting block；7, the first installing frame；71, sliding slot；72, first baffle；8, the second installing frame；9, the second bullet Spring；10, first clamping plate；101, sliding block；102, second baffle；11, the first agent plate；12, third spring；13, second clamping plate； 14, the second agent plate；15, Reagent Tube.

Specific embodiment

The following will be combined with the drawings in the embodiments of the present invention, carries out the technical scheme in the embodiment of the utility model Clearly and completely describe, it is clear that the described embodiments are only a part of the embodiments of the utility model, rather than whole Embodiment.Based on the embodiments of the present invention, those of ordinary skill in the art are without making creative work Every other embodiment obtained, fall within the protection scope of the utility model.

Fig. 1-3 is please referred to, the utility model provides a kind of technical solution: a kind of eight concussion instrument SNP grouping reagents dress It sets, including firm banking 1, the first spring of several groups 2, first bullet is fixedly installed on the upper surface of the firm banking 1 The upper end of spring 2 is connected with fixed plate 3, is fixedly installed on the upper surface of the firm banking 1 in the two sides at 2 both ends of the first spring There is the first fixed column 4, the upper end of first fixed column 4 is provided with the second fixed column 5, and the upper end of second fixed column 5 is solid It is arranged on the lower surface of fixed plate 3 calmly, the lower end of second fixed column 5 is threaded with adjusting rod by opening up internal screw thread 6, the two sides of 3 upper surface of fixed plate are respectively set fixed block 31 and are fixedly installed the first installing frame 7 and the second installing frame 8, Be fixedly installed several groups second spring 9 on the inner sidewall of first installing frame, 7 two sides, the second spring 9 it is another End is fixedly installed first clamping plate 10, and the first agent plate 11 is equipped between first installing frame 7 and first clamping plate 10, described Several groups third spring 12, the other end of the third spring 12 are fixedly installed on the inner sidewall of second installing frame, 8 two sides It is fixedly installed second clamping plate 13, the second agent plate 14 is installed between second installing frame 8 and second clamping plate 13, described Several Reagent Tubes 15 are fixedly installed on the upper surface of one agent plate 11 and the second agent plate 14.

The upper end of first fixed column 4 offers the threaded hole to match with adjusting rod 6, the length of the adjusting rod 6 It is longer than the distance between the first fixed column 4 and the second fixed column 5, it is fixedly installed adjusting block 61 on the adjusting rod 6, is conducive to Fixed plate 3 is fixed, while facilitating the rotation of adjusting rod 6；First spring 2, second spring 9 and third spring 12 At least six groups of quantity, be conducive to provide enough elastic force and guarantee fixed plate 3, first clamping plate 10, second clamping plate 13 it is steady It is qualitative；Sliding slot 71, the first clamping plate 10 are provided on the inner sidewall of 8 two sides of first installing frame 7 and the second installing frame It is provided with sliding block 101 with the two sides of second clamping plate 13, the sliding slot 71 is slidably connected with sliding block 101, is conducive to increase by first Stability when clamping plate 10 and the vibration of second clamping plate 13 or sliding；First installing frame 7 and the second installing frame 8 are in sliding slot 71 Lower end be provided with first baffle 72, second baffle 102 is provided in the first clamping plate 10 and second clamping plate 13, it is described First baffle 72 and second baffle 102 are in same level；Be conducive to carry out the first agent plate 11 and the second agent plate 14 It is fixed；The diameter of 15 upper end tube nozzle of Reagent Tube is smaller than the diameter of 15 pipe shaft of Reagent Tube, is beneficial to prevent in Reagent Tube 15 Reagent spills.

The lower end of firm banking 1: in use device, being fixed in eight concussion instruments by working principle first, then to Different reagent mixed liquors are instilled in Reagent Tube 15 in first agent plate 11 and in the second agent plate 14, then as needed, are turned Adjusting block 61 on dynamic adjusting rod 6 can be controlled effectively at a distance from 4 upper end of the first fixed column by controlling 6 lower end of adjusting rod The frequency of device body vibration processed, the present apparatus can adjust vibration frequency according to actual needs, and the mixed effect of reagent is more preferable, can To detect the gene of multiple groups difference cell simultaneously, detection effect is more preferable.

It should be noted that, in this document, relational terms such as first and second and the like are used merely to a reality Body or operation are distinguished with another entity or operation, are deposited without necessarily requiring or implying between these entities or operation In any actual relationship or order or sequence.Moreover, the terms "include", "comprise" or its any other variant are intended to Non-exclusive inclusion, so that the process, method, article or equipment including a series of elements is not only wanted including those Element, but also including other elements that are not explicitly listed, or further include for this process, method, article or equipment Intrinsic element.

While there has been shown and described that the embodiments of the present invention, for the ordinary skill in the art, It is understood that these embodiments can be carried out with a variety of variations in the case where not departing from the principles of the present invention and spirit, repaired Change, replacement and variant, the scope of the utility model is defined by the appended claims and the equivalents thereof.

Claims (6)

1. a kind of eight concussion instruments SNP grouping reagents device, including firm banking (1), it is characterised in that: the firm banking (1) the first spring of several groups (2) is fixedly installed on upper surface, the upper end of first spring (2) is connected with fixed plate (3), the first fixed column is fixedly installed in the two sides at the first spring (2) both ends on the upper surface of the firm banking (1) (4), the upper end of first fixed column (4) is provided with the second fixed column (5), and the upper end fixation of second fixed column (5) is set It sets on the lower surface of fixed plate (3), the lower end of second fixed column (5) is threaded with adjusting rod by opening up internal screw thread (6), the two sides of fixed plate (3) upper surface are respectively set fixed block (31) and are fixedly installed the first installing frame (7) and second Installing frame (8) is fixedly installed several groups second spring (9) on the inner sidewall of the first installing frame (7) two sides, described The other end of two springs (9) is fixedly installed first clamping plate (10), is pacified between first installing frame (7) and first clamping plate (10) Equipped with the first agent plate (11), several groups third spring is fixedly installed on the inner sidewall of the second installing frame (8) two sides (12), the other end of the third spring (12) is fixedly installed second clamping plate (13), second installing frame (8) and the second folder It is equipped between plate (13) the second agent plate (14), on the upper surface of first agent plate (11) and the second agent plate (14) It is fixedly installed several Reagent Tubes (15).

2. a kind of eight concussion instrument SNP grouping reagents device according to claim 1, it is characterised in that: described first The upper end of fixed column (4) offers the threaded hole to match with adjusting rod (6), and the length of the adjusting rod (6) is more fixed than first The distance between column (4) and the second fixed column (5) are long, are fixedly installed adjusting block (61) on the adjusting rod (6).

3. a kind of eight concussion instrument SNP grouping reagents device according to claim 1, it is characterised in that: described first At least six groups of the quantity of spring (2), second spring (9) and third spring (12).

4. a kind of eight concussion instrument SNP grouping reagents device according to claim 1, it is characterised in that: described first It is provided with sliding slot (71) on installing frame (7) and the inner sidewall of the second installing frame (8) two sides, the first clamping plate (10) and second The two sides of clamping plate (13) are provided with sliding block (101), and the sliding slot (71) is slidably connected with sliding block (101).

5. a kind of eight concussion instrument SNP grouping reagents device according to claim 1 or 4, it is characterised in that: described One installing frame (7) and the second installing frame (8) are provided with first baffle (72), the first clamping plate in the lower end of sliding slot (71) (10) and in second clamping plate (13) it is provided with second baffle (102), the first baffle (72) and second baffle (102) are same On one horizontal plane.

6. a kind of eight concussion instrument SNP grouping reagents device according to claim 1, it is characterised in that: the reagent The diameter for managing (15) upper end tube nozzle is smaller than the diameter of Reagent Tube (15) pipe shaft.