CN209500523U - A kind of preparation facilities that micropin is administered - Google Patents
A kind of preparation facilities that micropin is administered Download PDFInfo
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- CN209500523U CN209500523U CN201822068011.XU CN201822068011U CN209500523U CN 209500523 U CN209500523 U CN 209500523U CN 201822068011 U CN201822068011 U CN 201822068011U CN 209500523 U CN209500523 U CN 209500523U
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- Prior art keywords
- micropin
- hold
- spring
- template
- preparation facilities
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- 238000002360 preparation method Methods 0.000 title claims abstract description 30
- 230000007246 mechanism Effects 0.000 claims abstract description 27
- 238000000926 separation method Methods 0.000 claims abstract description 24
- 239000000463 material Substances 0.000 claims abstract description 20
- 230000006835 compression Effects 0.000 claims description 7
- 238000007906 compression Methods 0.000 claims description 7
- 239000012815 thermoplastic material Substances 0.000 abstract description 22
- 238000004519 manufacturing process Methods 0.000 abstract description 16
- 238000000034 method Methods 0.000 abstract description 14
- 230000008569 process Effects 0.000 abstract description 9
- 238000009776 industrial production Methods 0.000 abstract description 3
- 239000002994 raw material Substances 0.000 description 13
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 7
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 7
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 7
- 239000003814 drug Substances 0.000 description 6
- 230000008901 benefit Effects 0.000 description 5
- 238000010586 diagram Methods 0.000 description 5
- 229940069328 povidone Drugs 0.000 description 5
- 230000000975 bioactive effect Effects 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 238000000465 moulding Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 239000002210 silicon-based material Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000004512 die casting Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 238000001259 photo etching Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 238000005498 polishing Methods 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- Media Introduction/Drainage Providing Device (AREA)
Abstract
The utility model discloses a kind of preparation facilities that micropin is administered, preparation facilities includes the upper plate set gradually from top to bottom, template, soft liner, separation layer and bottom plate, upper plate, template, soft liner, separation layer and bottom plate are heat-resisting material, separation layer is gas-permeable, liquid-impermeable material, template is equipped with micropore corresponding with the spicule of micropin area, there are several micropores in one micropore area, micropore is the through-hole being provided in template, the position that micropore area is corresponded on the upper plate offers up big and down small stepped hole, the top of upper plate is equipped with hold-down mechanism, hold-down mechanism includes the hold-down head for being inserted into the big section on stepped hole top, the size of hold-down head is less than the size of stepped hole lower part segment.The micropin preparation facilities of the utility model is easy to use, operating process is simple, micropin can be made to realize industrial production, and thermoplastic material is easy to get, and can reduce micropin production cost.
Description
Technical field
The utility model relates to a kind of preparation facilities that micropin is administered, and belong to technical field of medical equipment.
Background technique
It is microneedle cutaneous to be used as a kind of novel Transdermal delivery systems, collect subcutaneous administrations mode and transdermal patch administration
The advantages of in one, it is not only painless minimally invasive, but also drug absorption efficiency is high.In addition, micropin be administered when patient can self-administration, side
Just safety.Therefore, microneedle cutaneous technology just obtains extensive concern from appearance is started.The basic structure shape of micropin is administered
State is: suitable thickness, suitable shape (being such as but not limited to round, rectangular etc.) substrate on (be such as but not limited to plate, arc
Shape plate etc.), on end one group of miniature spicule in varying numbers.The basic use process and principle of micropin are as follows: in convenient pressure
Under the action of, skin passage is strutted using micropin, the bioactive substances such as drug is helped to pass through skin, realizes whole body or skin office
The distribution of the bioactive substances such as portion's drug, reaches treatment or other beneficial effects, has very positive meaning.
The micropin of the prior art has metal solid microneedles, metal hollow fine needle, nonmetallic materials solid microneedles (such as inorganic silicon
Material), organic macromolecule material micropin (such as povidone), still, these existing micropin products and preparation method thereof are all deposited
There is the difficulty of volume production preparation aspect, causes such technology and product so far there are no the case of industrial production scale to occur, and because of it
The limitation of volume production ability causes cost of manufacture also higher.
The production of metal micro-needle is related to the complex techniques process of precision machinery processing or accuracy electroplate film forming, it is difficult to low cost
Scale volume production, and the presence of the rigidity and machined burrs of metal material, skin are quite obvious to the foreign body sensation of micropin.
The melting temperature of inorganic silicon materials is too high, it is difficult to find suitable high-temperature resistance die, carry out the micropin of heat note technique
Production；Inorganic silicon material hardness height under the state of cooling, brittleness are big, and the process efficiency of cutting, polishing or photoetching is lower.
Povidone (PVP) concentrated solution through die casting at micropin, the micropin of the PVP material after drying and moulding, because of intensity
Deficiency, knockout course are more difficult.Mold used in povidone micropin preparation process is the template with micropore, due to micro-
Hole is the form of counterbore, and micropore size very little, and when being poured povidone solution in order to prevent, povidone solution is by micro porous hollow gas
Obstruction can not sink to micropore bottom, in micropin manufacturing process, need for whole equipment to be placed in closed container, will be closed
Container vacuum-pumping results in manufacturing process with regard to cumbersome in this way, and cost of manufacture will increase.
Utility model content
The purpose of this utility model is to provide a kind of preparation facilities that micropin is administered, to solve the micropin system of the prior art
Make cumbersome, it is at high cost, cannot achieve the technical issues of volume production.
The preparation facilities of the administration micropin of the utility model adopts the following technical scheme that a kind of preparation dress that micropin is administered
It sets, including upper plate, template, separation layer, soft liner and the bottom plate set gradually from top to bottom, the upper plate, template, isolation
Layer, soft liner and bottom plate are heat-resisting material, and the separation layer is gas-permeable, liquid-impermeable material, and the template is equipped with and micropin
The corresponding micropore area of spicule, have several micropores in a micropore area, micropore is the through-hole being provided in template, it is described on
The position that micropore area is corresponded on plate offers up big and down small stepped hole, and the top of upper plate is equipped with hold-down mechanism, hold-down mechanism packet
The hold-down head in the big section for being inserted into stepped hole top is included, the size of hold-down head is greater than the size of stepped hole lower part segment.
The hold-down mechanism includes the compressor arm being fixedly connected on above hold-down head, and the hold-down head integrally connects with compressor arm
It connects, spring is arranged on compressor arm, the spring-compressed mechanism for compressed spring is equipped with above spring.
The spring-compressed mechanism includes pressure plate, and the through-hole passed through for compressor arm is offered on the pressure plate, described
Spring is set on compressor arm the position between pressure plate and hold-down head, and compression stud, institute are coated in the pressure plate
It states the position spiral for compressing and being located above pressure plate on stud and is equipped with clamp nut or handwheel.
Positioning plate is additionally provided on the upper plate, the position that each stepped hole is corresponded on positioning plate offers location hole, fixed
The diameter in position hole is equal to the diameter of hold-down head, and the hold-down head passes through location hole and is inserted into the big section on stepped hole top.
The spring-compressed mechanism includes sleeve and the clamping cap for being threaded in sleeve upper end, the stepped hole top
It is equipped with the internal screw thread cooperated with sleeve lower thread in big section, the lower thread of sleeve is connected in the big section on stepped hole top,
The compressor arm and spring include ring wall surface and are connected to ring wall surface top for being mounted on sleeve inner, the clamping cap
Top cover, the top cover, which is equipped with, passes through hole for compressor arm, and the ring wall surface spiral is assemblied in sleeve upper end, and top cover compresses bullet
Spring.
Soft super gasket is additionally provided between the big section and hold-down head on the stepped hole top.
Positioning bolt is equipped between the upper plate and bottom plate.
The quantity at least two in micropore area in the template, the quantity of the upper plate upper shoulder hole and the quantity in micropore area
It is equal.
The beneficial effects of the utility model are: the micropin preparation process of the utility model is that the raw material for preparing micropin exists
Soften under certain temperature or melt or melt, becomes the mobility state of software or fluid with certain morphotropism, mobility
Raw material enter the micropore of template after, then by press molding, cooling, demoulding and be made.It is micro- in the utility model template
Hole is through-hole, does not need to operate under vacuum conditions, and the thermoplastic material with mobility will inject inside micropore, and press
The pressure of tight head acts on lower thermoplastic material and the air in micropore can be squeezed away, and the separation layer of gas-permeable, liquid-impermeable material facilitates through
Air, and thermoplastic material then will not be through being lost, soft pad can guarantee that upper plate and separation layer are in close contact, and prevent thermoplasticity
Raw material squeezes out in the gap between upper plate and separation layer.The micropin preparation facilities of the utility model is easy to use, operating process
Simply, micropin can be made to realize industrial production, and thermoplastic material is easy to get, and is more conducive to large-scale production, to reduce
Micropin production cost.The micropin of the utility model thermoplasticity material have the advantage that first is that safety, do not cause skin allergy；
Second is that there is suitable hardness, micropin spicule had not only been enough to strut skin but also less had been with or without foreign body sensation；Third is that it is not soluble in water, with
The micropin spicule for exempting to be inserted into skin is partly dissolved in vivo, so that the quick closedown of skin duct, influences Subsequent pharmacological entrance；Four
It is that heat is melted or hot melting temperature is moderate, the micropin spicule after forming has toughness, convenient for demoulding.However, the micropin of the prior art
Material cannot then be provided simultaneously with these advantages.The administration micropin prepared using the device and method of the utility model is actually
It is blank micropin, after blank micropin is made, through suitable method, suitable drug or other bioactive substances is loaded in micro-
On needle especially needle point position, the micropin for carrying medicine or being loaded with bioactive substance is made, for medical treatment or other beneficial purposes.
Preferably, spring is set on compressor arm, using spring-compressed mechanism compressed spring, to be applied to hold-down head
Power, to compress thermoplastic material.
Preferably, using pressure plate and stud compressed spring is compressed, when use rotatably compresses nut or handwheel, makes pressure plate
It moves down, so that compressed spring pressurizes to thermoplastic material, pressure plate is integrally moved down, thermoplastic material uniform force, manufacture
Micropin specification out is consistent, is conducive to improve the quality of production.
Preferably, using sleeve and clamping cap compressed spring, when use, which rotatably compresses lid, can make spring-compressed, to realize
It pressurizes to thermoplastic material, with simple, the easy to operate advantage of structure, is conducive to testing crew and voluntarily processes in the lab
Production.
Preferably, hold-down head pressurizes to thermoplastic material across super gasket, and surface nature and heat can be selected in super gasket
The material that plastic raw material differs greatly, and then prevent hold-down head from adhering to thermoplastic material, and thermoplastic material uniform force, it produces
Quality is good.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of the preparation facilities embodiment 1 of the administration micropin of the utility model；
Fig. 2 is the enlarged drawing of part A in Fig. 1；
Fig. 3 is the structural schematic diagram of upper plate in Fig. 1；
Fig. 4 is the structural schematic diagram of template in Fig. 1；
Fig. 5 is the structural schematic diagram of the preparation facilities embodiment 2 of the administration micropin of the utility model.
In figure, 1- upper plate, 2- template, 21- micropore area, 3- separation layer, the soft liner of 4-, 5- bottom plate, 6- hold-down mechanism,
61- hold-down head, 62- compressor arm, 63- spring, 64- pressure plate, 65- compress stud, 66- clamp nut, 67- positioning plate, 68- pressure
Tight lid, 681- ring wall surface, 682- top cover, 69- sleeve, 7- super gasket.
Specific embodiment
The utility model is described in detail in the following with reference to the drawings and specific embodiments.
The structure of the preparation facilities embodiment 1 of the administration micropin of the utility model is as shown in Figures 1 to 4, and the present embodiment is given
The preparation facilities of medicine micropin includes the upper plate 1 set gradually from top to bottom, template 2, separation layer 3, soft liner 4 and bottom plate 5, institute
Stating upper plate 1, template 2, separation layer 3, soft liner 4 and bottom plate 5 is heat-resisting material, and the separation layer 3 is gas-permeable, liquid-impermeable material
Matter, the template 2 are equipped with micropore corresponding with the spicule of micropin area 21, have several micropores, micropore in a micropore area
For the through-hole being provided in template 2, the position that micropore area 21 is corresponded on the upper plate 1 offers up big and down small stepped hole.On
The top of plate 1 is equipped with hold-down mechanism 6, and hold-down mechanism 6 includes the hold-down head 61 for being inserted into the big section on stepped hole top, pressure
The size of tight head 61 is greater than the size of stepped hole lower part segment, and the size on big section of preferred hold-down head and stepped hole top is identical,
Soft super gasket 7 is additionally provided between the big section and hold-down head on stepped hole top.
In the present embodiment, the hold-down mechanism includes the compressor arm 62 for being fixedly connected on 61 top of hold-down head, the compression
First 61 with 62 integrally connected of compressor arm, spring 63 is arranged on compressor arm, the spring for compressed spring is equipped with above spring 63
Compression mechanism.The spring-compressed mechanism includes pressure plate 64, offers on the pressure plate 64 and leads to for what compressor arm 62 passed through
Hole, the spring 63 are set in the position on compressor arm 62 between pressure plate 64 and hold-down head 61, in the pressure plate 64
It is coated with and compresses stud 65, the position spiral being located above pressure plate on stud 65 that compresses is equipped with clamp nut 66 or hand
Wheel.Positioning plate 67 is additionally provided on the upper plate, the position that each stepped hole 11 is corresponded on positioning plate 67 offers location hole, fixed
The diameter in position hole is equal to the diameter of hold-down head, and the hold-down head 61 passes through location hole and is inserted into the big section on 11 top of stepped hole.
The quantity at least two in the micropore area 21 in the template, quantity and the micropore area of the upper plate upper shoulder hole
Quantity is equal, as shown in figure 3,21 quantity of micropore area on this case template is 8,8 micropore areas are distributed on template, pressure
Tight stud presses to the spring on compressor arm corresponding to 8 micropore areas by pressure plate, is conducive to the raw material in each micropore area
Uniform force.Certainly, the present embodiment is also only schematic diagram, and in other embodiments, the quantity in micropore area should be according to reality
It needs flexibly to select.
The micropin preparation process of the present embodiment is that the raw material for preparing micropin is softened or melted at a certain temperature or is melted
Change, becomes the mobility state of software or fluid with certain morphotropism.The process for heating raw material can be in the utility model
Device outside carry out, can also be carried out inside the device of the utility model.After the raw material of mobility enters the micropore of template,
Then by press molding, cooling, demoulding and be made.Micropore in the utility model template is through-hole, is not needed in vacuum ring
It is operated under border, the thermoplastic material of flow regime will inject inside micropore, and thermoplasticity is former under the effect of the pressure of hold-down head
Material can squeeze away the air in micropore, and the separation layer of gas-permeable, liquid-impermeable material facilitates through air, and thermoplastic material then will not
Through soft pad can guarantee that upper plate and separation layer are in close contact, and prevent seam of the thermoplastic material between upper plate and separation layer
It is squeezed out in gap.The present embodiment is using pressure plate and to compress stud compressed spring, and when use rotatably compresses nut, make pressure plate to
Lower movement, so that compressed spring pressurizes to thermoplastic material, pressure plate is integrally moved down, and thermoplastic material uniform force produces
Micropin specification it is consistent, be conducive to improve the quality of production.
The structure of the preparation facilities embodiment 2 of the administration micropin of the utility model is as shown in figure 5, the administration of the present embodiment is micro-
The preparation facilities of needle, it is described including upper plate 1, template 2, separation layer 3, soft liner 4 and the bottom plate 5 set gradually from top to bottom
Positioning bolt 8 is equipped between upper plate 1 and bottom plate 5.The upper plate 1, template 2, separation layer 3, soft liner 4 and bottom plate 5 are resistance to
Hot material, the separation layer 3 are gas-permeable, liquid-impermeable material, and the template 2 is equipped with micropore corresponding with the spicule of micropin area
21, there are several micropores in a micropore area 21, micropore is the through-hole being provided in template, corresponds to micropore area on the upper plate 1
21 position offers up big and down small stepped hole, and the top of upper plate 21 is equipped with hold-down mechanism 6, and hold-down mechanism 6 includes for inserting
Enter to the hold-down head 61 in the big section on stepped hole top, the size of hold-down head 61 is greater than the size of stepped hole lower part segment, preferably
The size on big section of hold-down head and stepped hole top it is identical,.It is additionally provided between the big section and hold-down head 61 on the stepped hole top
Soft super gasket 7, the size of gasket 7 are greater than the size of stepped hole lower part segment, shape diameter and 61 phase of hold-down head of gasket 7
Together.
In the present embodiment, hold-down mechanism includes the compressor arm 62 for being fixedly connected on 61 top of hold-down head, the hold-down head 61
With 62 integrally connected of compressor arm, it is arranged with spring 63 on compressor arm, the spring-compressed for compressed spring is equipped with above spring 63
Mechanism.The spring-compressed mechanism of the present embodiment includes sleeve 69 and the clamping cap 68 for being threaded in 69 upper end of sleeve, the rank
The internal screw thread cooperated with 69 lower thread of sleeve is equipped in the big section on terraced 11 top of hole, the lower thread of sleeve 69 is connected to ladder
In the big section on 11 top of hole, for being mounted on inside sleeve 69, the clamping cap 68 includes ring for the compressor arm 62 and spring 63
Shape wall surface 681 and the top cover 682 for being connected to 681 top of ring wall surface, the top cover 682, which is equipped with, passes through hole, institute for compressor arm
It states 681 spiral of ring wall surface and is assemblied in 69 upper end of sleeve, top cover holddown spring.
The micropin preparation process of the present embodiment is that the raw material for preparing micropin is softened or melted at a certain temperature, is become
The mobility state of software or fluid with certain morphotropism.The process for heating raw material can be outside the device of the utility model
Portion carries out, and can also carry out inside the device of the utility model.After the raw material of mobility enters the micropore of template, then pass through
Press molding, cooling, demoulding and be made.Micropore in the utility model template is through-hole, does not need to operate under vacuum conditions,
The thermoplastic material of flow regime will inject inside micropore, and thermoplastic material can be micropore under the effect of the pressure of hold-down head
In air squeeze away, the separation layer of gas-permeable, liquid-impermeable material facilitates through air, and thermoplastic material will not then penetrate, soft lining
It pads and can guarantee that upper plate and separation layer are in close contact, prevent thermoplastic material from squeezing out in the gap between upper plate and separation layer.This
The use process of the hold-down mechanism of embodiment are as follows: the lower part of sleeve is screwed in the big section of upper board step hole, is put in sleeve
After entering super gasket, then compressor arm is put into sleeve inner, clamping cap is then screwed in upper cartridge again, and make compressor arm from
It is pierced by threaded hole on clamping cap, the compression that lid realizes spring is rotatably compressed, so that hold-down head adds gasket and raw material
Pressure.The present embodiment is pressurizeed with the compressor arm with spring to thermoplastic material using sleeve, has structure simple, operation
Convenient advantage is conducive to testing crew voluntarily processing and fabricating in the lab.
Above-described embodiment is the utility model preferred embodiment, in the other embodiments of the utility model, compacting machine
Structure can be with driving devices such as hydraulic cylinder, pneumatic cylinder or motors, as long as energy band, which moves hold-down head, moves down compression micropin raw material
?.The quantity in micropore area is flexible choice according to actual needs.
Although the embodiments of the present invention is described in detail in the embodiment above, this is practical new
Type is not limited to above-mentioned embodiment, and the scope of the utility model defined by the attached claims includes all equivalent replaces
Generation and variation.
Claims (8)
1. a kind of preparation facilities that micropin is administered, it is characterised in that: it includes the upper plate (1) set gradually from top to bottom, template
(2), separation layer (3), soft liner (4) and bottom plate (5), the upper plate (1), template (2), separation layer (3), soft liner (4)
And bottom plate (5) is heat-resisting material, the separation layer (3) is gas-permeable, liquid-impermeable material, and the template (2) is equipped with and micropin
The corresponding micropore area (21) of spicule, a micropore area (21) is interior several micropores, and micropore is to be provided with leading on template (2)
Hole, the position that micropore area (21) is corresponded on the upper plate (1) offer up big and down small stepped hole (11), and the top of upper plate is equipped with
Hold-down mechanism (6), hold-down mechanism (6) include the hold-down head (61) for being inserted into the big section on stepped hole (11) top, are compressed
The size of head (61) is greater than the size of stepped hole (11) lower part segment.
2. the preparation facilities of administration micropin according to claim 1, it is characterised in that: the hold-down mechanism includes fixed connects
The compressor arm (62) above hold-down head (61), the hold-down head (61) and compressor arm (62) integrally connected are connect, is covered on compressor arm
Equipped with spring (63), the spring-compressed mechanism for compressed spring is equipped with above spring (63).
3. the preparation facilities of administration micropin according to claim 2, it is characterised in that: the spring-compressed mechanism includes pressure
Tight plate (64) offers the through-hole passed through for compressor arm (62) on the pressure plate (64), and the spring (63) is set in compression
Position on bar (62) between pressure plate (64) and hold-down head (61), the pressure plate (64) is interior to be coated with compression stud
(65), the position spiral being located above pressure plate on stud (65) that compresses is equipped with clamp nut (66) or handwheel.
4. the preparation facilities of administration micropin according to claim 3, it is characterised in that: be additionally provided with positioning plate on the upper plate
(67), the position that each stepped hole (11) is corresponded on positioning plate (67) offers location hole, and the diameter of location hole, which is equal to, to be compressed
The diameter of head, the hold-down head (61) pass through location hole and are inserted into the big section on stepped hole (11) top.
5. the preparation facilities of administration micropin according to claim 2, it is characterised in that: the spring-compressed mechanism includes set
Cylinder (69) and be threaded in the clamping cap (68) of sleeve (69) upper end, in the big section on stepped hole (11) top equipped with and set
The internal screw thread of cylinder (69) lower thread cooperation, the lower thread of sleeve (69) are connected in the big section on stepped hole (11) top, institute
It is internal for being mounted on sleeve (69) to state compressor arm (62) and spring (63), the clamping cap (68) includes ring wall surface (681)
With the top cover (682) for being connected to ring wall surface (681) top, the top cover (682), which is equipped with, passes through hole, the ring for compressor arm
Shape wall surface (681) spiral is assemblied in sleeve (69) upper end, top cover holddown spring.
6. according to claim 1 to the preparation facilities that micropin is administered described in 5 any one, it is characterised in that: the stepped hole
(11) soft super gasket (7) are additionally provided between the big section and hold-down head on top.
7. according to claim 1 to the preparation facilities that micropin is administered described in 5 any one, it is characterised in that: the upper plate (1)
Positioning bolt (8) are equipped between bottom plate (5).
8. according to claim 1 to the preparation facilities that micropin is administered described in 5 any one, it is characterised in that: the template (2)
The quantity at least two of upper micropore area (21), the quantity and the quantity phase of micropore area (21) of the upper plate upper shoulder hole (11)
Deng.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822068011.XU CN209500523U (en) | 2018-12-11 | 2018-12-11 | A kind of preparation facilities that micropin is administered |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822068011.XU CN209500523U (en) | 2018-12-11 | 2018-12-11 | A kind of preparation facilities that micropin is administered |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN209500523U true CN209500523U (en) | 2019-10-18 |
Family
ID=68193709
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201822068011.XU Withdrawn - After Issue CN209500523U (en) | 2018-12-11 | 2018-12-11 | A kind of preparation facilities that micropin is administered |
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| Country | Link |
|---|---|
| CN (1) | CN209500523U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111298279A (en) * | 2018-12-11 | 2020-06-19 | 尹忠 | Preparation device and preparation method of drug delivery microneedle |
-
2018
- 2018-12-11 CN CN201822068011.XU patent/CN209500523U/en not_active Withdrawn - After Issue
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111298279A (en) * | 2018-12-11 | 2020-06-19 | 尹忠 | Preparation device and preparation method of drug delivery microneedle |
| CN111298279B (en) * | 2018-12-11 | 2024-01-26 | 尹忠 | Preparation device and preparation method of drug administration microneedle |
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