CN209416456U - A kind of medical micrometeor injection intelligence calibration system - Google Patents

A kind of medical micrometeor injection intelligence calibration system Download PDF

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Publication number
CN209416456U
CN209416456U CN201821780384.3U CN201821780384U CN209416456U CN 209416456 U CN209416456 U CN 209416456U CN 201821780384 U CN201821780384 U CN 201821780384U CN 209416456 U CN209416456 U CN 209416456U
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medical
circuit
micrometeor
module
flow
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刘平进
赵鹏
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GANSU INSTITUTE OF METROLOGY
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GANSU INSTITUTE OF METROLOGY
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Abstract

The utility model relates to field of medical device, specially a kind of medical micrometeor injection intelligence calibration system;The present apparatus is powered using master controller as core processing unit by electric power source pair of module master controller, while master controller is connect by circuit with flow sensor, radio receiving transmitting module, display screen and pressure sensor.In use, flow sensor and pressure sensor to be connect to the measurement, it can be achieved that flow velocity and pressure with perfusion tube;It has the advantage that: the present apparatus passes through the double check of flow sensor and pressure sensor, and it is controlled by the calculating of main control module, high control precision is mentioned, medical tiny flow quantity injection is embodied as, is especially controlled in the quality of (0.1~20.0) ml/h flow section.

Description

A kind of medical micrometeor injection intelligence calibration system
Technical field
The utility model relates to field of medical device, specially a kind of medical micrometeor injection intelligence calibration system.
Background technique
With the development of science and technology, precisely the theory of medical treatment is increasingly used in treatment clinical courses at different levels.It is medical Micrometeor injecting systems are mainly applicable in range of flow (1~10) ml/h infusion and injection treatment Medical Devices, and reference is being faced at present Mainly microinfusion pump and the micro-injection pump of bed, are widely used in the critical clinicals such as operating room, ICU, CCU department.By It is few in dose, injection time is long, therefore clinical treatment has high requirement to its flow accuracy, flow repeatability, thereon It states metering performance and is directly related to the quality of medical care even life security of patient.In order to guarantee that the quality of clinical diagnosis, protection are suffered from The health of human body of person, establishes that medical micrometeor injecting systems magnitude tracing system is imperative, and State Administration of Quality Supervision, Inspection and Quarantine has promulgated " medical injection Penetrate pump and infusion pump calibrating standard " (JJF1259-2010).With the Ministry of Public Health's " medical instrument clinical use safety management in 2010 Specification " require hospital that must set up " the medical instrument clinical use safety management committee " in (tentative), it is wanted in buying examination Ask carry out quality test;It is inspected periodically and Quality Control plan and implementing plan, the calibrating installation according to inhomogeneity product requirement Larger medical health organ and gauge check department at different levels will be widely used in.Therefore the autonomous medical micrometeor in China is developed Injecting systems intelligent high-speed calibrating installation is very urgent.
Existing foreign countries' calibration cartridge is equipped with FLUKE company, the U.S., S.P.L company, Germany, and the country is without such calibrating installation Production.Above-mentioned foreign corporation's product is usually more focused on (20~1000) ml/h measurement range, and surveys in (1~10) ml/h flow It measures in range not exclusively controllably, and this partial discharge accuracy is exactly that hospital clinical is most concerned.And above-mentioned calibrating installation exists The problems such as it is lower that there are calibration efficiencies in actual alignment work, and time limit is slow.With universal, the medical micrometeor of accurate medical treatment Injecting systems are widely used in treatment clinical courses at different levels, therefore device research research and development are very necessary.
Utility model content
The utility model provides a kind of medical micrometeor injection intelligence calibration system, effective solution background technique The problem of, the present apparatus passes through the double check of flow sensor and pressure sensor, and the calculating for passing through main control module Control, mentions high control precision, is embodied as medical tiny flow quantity injection, especially the quality control in (0.1~20.0) ml/h flow section System.
To achieve the above object, the utility model is as follows using concrete scheme:
A kind of medical micrometeor injection intelligence calibration system, it is characterised in that: this system uses main control module for processing Unit is equipped with flow sensor, pressure sensor, display screen, radio receiving transmitting module and power module, power supply in this system Module is master control modules with power, while main control module carries out bi-directional data by circuit and display screen and radio receiving transmitting module Transmission;
The main control module is connect by CPLD logic analysis module with flow sensor, flow sensor and perfusion tube phase It connects, induction detection is carried out to infusion rate;
The main control module amplifies conditioning circuit by blockage pressure and connect with pressure sensor, pressure sensor and infusion Pipe is interconnected, and carries out induction detection to infusion pressure.
The main control module selects MSP430 single-chip microcontroller, and MSP430 main control part is by MSP430F5438A minimum system group At minimum system is made of JTAG interface circuit, reset circuit and clock circuit three parts.
The CPLD, as master clock signal source, supports JTAG downloading mode pair using the quartz oscillator of 20MHz EPM240GT100C5N chip carries out on-line system programming and configuration, and one 32 meters are designed using CPLD logic analysis module Device is counted, when the maximum long-time that 3436s may be implemented is surveyed after clock division, when the most short 0.8us that can be realized is surveyed for a long time.
Pressure sensor amplification conditioning circuit constitutes input stage with phase operational amplifier circuit by two, with difference amplifier Three amplifier differential amplifier circuits are composed in series, related resistance keeps Striking symmetry in circuit.
Especially exist the utility model has the following beneficial effects: clinical treatment has successfully been filled up in the research of the device in tiny flow quantity The blank of (0.1~20.0) ml/h flow section quality control requirements, and better than State General Administration for Quality Supervision in " medical injection pump and infusion Calibration of pump specification " requirement in (JJF1259-2010) for measurement criteria.The device is with integration degree is high, carrying side Just, the features such as low to use environment temperature requirement, operating automation degree is high, carries out detection work convenient for testing agency scene. This calibration system is widely portable to medical instrument quality surveillance detection departments at different levels simultaneously and measurement verification calibration department carries out Related fields quality inspection or measurement and calibration work.
Detailed description of the invention
Fig. 1 is the utility model structure diagram;
Fig. 2 is the utility model measuring circuit structural schematic diagram;
Fig. 3 is MSP430F5438A minimum system circuit diagram;
Fig. 4 is CPLD logic analysis circuit circuit diagram;
Fig. 5 is pressure sensor amplification conditioning Acquisition Circuit circuit diagram;
Fig. 6 is 5ml measurement point experiment value distribution map;
Fig. 7 is 20ml measurement point experiment value distribution map;
Fig. 8 is 50ml measurement point experiment value distribution map;
Specific embodiment
With reference to the accompanying drawing and pass through specific embodiment further instruction the technical solution of the utility model includes:
Embodiment 1
The utility model provides a kind of medical micrometeor injection intelligence calibration system, it is desirable to provide intelligent, high speed , it is able to satisfy the calibration system of tiny flow quantity section quality control requirements.Calibration system is equipped with micro-flow measurement part and obstruction pressure Power measures part.
Flow is most important index in medical micrometeor injecting systems, at present by taking infusion pump, syringe pump as an example, Flow adjustable extent is 0.1ml/h~999.9ml/h, and practical hospital is defeated, note uses range of flow for 5ml/h~150ml/h, is pressed The requirement of measurement range and " medical injection pump and infusion pump calibrating standard " (JJF1259-2010) according to detected object, high-ranking officers The flow measurement range of standard apparatus is designed as 0.1ml/h~300ml/h, develops measurement range in flow rate of liquid: (20.0~ 300) when ml/h, the limits of error ± 1%;Flow rate of liquid: when (0.1~20.0) ml/h, the limits of error ± 2%.
Medical micrometeor injecting systems stop infusion because fluid path is blocked in use, will be defeated when turning round such as patient Liquid pipeline is pushed down and other reasons such as block via.If not generating blockage pressure alarm, infusion drug fails to timely enter patient It can cause malpractice in vivo.The blockage pressure of medical micrometeor injecting systems is usually within 150kPa, in " medical injection pump With infusion pump calibrating standard " it requires in (JJF1259-2010) to detect retaining pressure, pressure limit is (0~200) KPa, therefore the blockage pressure measurement range of medical micrometeor injecting systems intelligent high-speed calibrating installation is designed as (0~230) kPa。
As shown in Figure 1, the present apparatus using master controller as core processing unit, is supplied by electric power source pair of module master controller Electricity, while master controller is connect by circuit with flow sensor, radio receiving transmitting module, display screen and pressure sensor.It uses When, flow sensor and pressure sensor are connect to the measurement, it can be achieved that flow velocity and pressure with perfusion tube.
Entire entire detection system mainly by main control module, CPLD control module, flow sensor, LCD MODULE, Contact control module and power management module composition, as shown in Figure 2.
Main control module selects MSP430F5438A as master controller, and main feature has following: 1) low-work voltage Range: 1.8V~3.6V;2) extremely low operating current loss: 165uA/MHz;3) LQFP100 is encapsulated, and 87 general purpose I/O draw Foot, including 16 exterior interrupts;4) up to 256KB in-chip FLASH memory, 16KB RAM memory;5) on 16 dust pieces 12 ADC;6) 3 16 general purpose timers.
MSP430F5438A controls a member as MSP430 single-chip microcontroller of chip, there is low in energy consumption, furthermore quantity Peripheral hardware and powerful register management system are that providing for entire detector design is good in numerous I/O pin, abundant piece Basic platform.MSP430 main control part is made of MSP430F5438A minimum system, as shown in figure 3, being entire test macro Core, carry out signal acquisition, the calculation processing, transmission of data, minimum system is made of following three parts:
1) JTAG interface circuit, JTAG programming mode can carry out online programming to FLASH, change in traditional mode of production process Pre-programmed is first carried out to chip, it is then mounted on the plate again, but first by device fixation, write-in program, program can also repair at any time again Change and re-writes.Jtag interface can also cooperate IAR volume to unravel silk software, test program on-line debugging, found out existing for program in time Problem can greatly improve programming efficiency.
2) reset circuit, when system electrification, provide reset signal, until cancelling reset signal after power good.
3) clock circuit, the work of single-chip microcontroller are on the basis of clock, and clock circuit is exactly for providing for single-chip microcontroller The circuit of clock signal, stable operation are the bases of SCM system stable operation.
CPLD logic analysis module, as master clock signal source, is supported under JTAG using the quartz oscillator of 20MHz Load mode carries out on-line system programming and configuration to EPM240GT100C5N chip, and main circuit is as shown in figure 4, main feature Have following: 1) 240 logic units (LE);2) 8Kb nonvolatile storage space;3) pin is to the pin most fast time: 4.5ns.CPLD logic analysis module mainly completes function: certain frequency arteries and veins is issued when being flowed through by flow sensor induced liquid Punching, flow is higher, and sending pulse frequency is higher, otherwise the lower sending pulse frequency of flow is lower.It is determined by frequency values Flow value size.The flow measurement range of calibrating installation is designed as 0.1ml/h~300ml/h, to so wide range of flow, stream From 0.1Hz to tens Hz, 0.1ml/h flow usually requires just export a pulse in 15 minutes for the pulse of quantity sensor output. But it only needs 0.5s less than a pulse can be exported when 300ml/h flow, to complete the time precise measurement of so wide-range, It is only more complicated by MSP430F5438A master control completion, and measurement accuracy is not also high.It is designed using CPLD logic analysis module One 32 counters, when the maximum long-time that 3436s may be implemented is surveyed after clock division, the most short 0.8us that can be realized When surveying for a long time, meet flow sensor enough for low discharge measurement request.
Pressure sensor selects differential pressure pickup according to the claimed range of design object, and main performance is as follows: 1) pressure Measurement range: 0~200kPa, maximum pressure resistance 400kPa;2) sensor signal output area: 0~40mV, differential pressure output signal; Pressure magnetic hysteresis < 0.1%FS.It is 40mV that pressure sensor, which exports full range voltage, this signal belongs to small voltage signal, needs Signal is amplified 125 times to export to 5V.The pressure voltage signal of amplification is subjected to analog to digital conversion, acquisition signal is filtered equal part Analysis processing.Wherein ADC digital analog converter major functions and features are as follows: 1) single-voltage-supply cmos: 2.7V~5V;2) AD conversion digit 16 Position measures minimum differentiate in pressure measurement range and reaches 0.003kPa;3) highest conversion ratio: 100kHz.Meet pressure survey enough Amount demand.Pressure sensor amplification conditioning circuit as shown in figure 5, constitute input stage with phase operational amplifier circuit by two, with difference Amplifier is composed in series three amplifier differential amplifier circuits, and related resistance keeps Striking symmetry in circuit, this circuit improves differential mode The ratio between signal and common-mode signal improve the signal-to-noise ratio of pressure sensor output signal.
Wireless module uses APC220-43 wireless module, integrates half pair of function micropower wireless data transfer module, insertion High-speed microprocessor and high-performance radio-frequency chip, production efficient circulation intertexture error correction and detection coding, the anti-interference and sensitivity of innovation All load is high significantly, and maximum can entangle the continuous burst error of 24bits, reach top standard in the industry.Module provides the choosing of multiple channels Select, can the various parameters such as online modification serial ports rate, transmission power and radio frequency rate, can any size data of transparent transmission, pass Defeated distance is remote.
Medical injection pump is had chosen in clinical medical micrometeor injecting systems as main sample carries out prototype test. 18 brands of market mainstream brand are chosen altogether, and 24 models, total 150 have carried out prototyping testing, specific data such as the following table 1, quilt Each point tolerance distribution of sample is as shown in Fig. 6, Fig. 7, Fig. 8.
Medical micro-injection pump test data
This research project develops medical micrometeor injecting systems intelligent high-speed calibrating installation one, model machine, passes through third party Legal measurement technology mechanism detects it, model machine all technical are as follows: flow rate of liquid in (20.0~300) ml/h, The limits of error 0.9%;Flow rate of liquid: when (0.1~20.0) ml/h, the limits of error 1.1%.Pressure measurement range: (0~230) kPa, the limits of error 0.8%.By above-mentioned detection data, whole device technical indicator is demonstrated better than design Requirement, the research of the device successfully filled up clinical treatment in tiny flow quantity especially in (0.1~20.0) ml/h flow section matter Measure the blank of demand for control and better than State General Administration for Quality Supervision in " medical injection pump and infusion pump calibrating standard " (JJF1259- 2010) for the requirement of measurement criteria in.
It is obvious to a person skilled in the art that the present invention is not limited to the details of the above exemplary embodiments, and And without departing substantially from the spirit or essential attributes of the utility model, it can realize that this is practical new in other specific forms Type.Therefore, in all respects, the present embodiments are to be considered as illustrative and not restrictive, this is practical new The range of type is indicated by the appended claims rather than the foregoing description, it is intended that containing for the equivalent requirements of the claims will be fallen in All changes in justice and range are embraced therein.It should not treat any reference in the claims as limiting Related claim.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art The other embodiments being understood that.

Claims (4)

1. a kind of medical micrometeor injection intelligence calibration system, it is characterised in that: this system uses main control module single for processing Member is equipped with flow sensor, pressure sensor, display screen, radio receiving transmitting module and power module, power supply mould in this system Block is master control modules with power, while main control module carries out bi-directional data biography by circuit and display screen and radio receiving transmitting module It is defeated;
The main control module is connect by CPLD logic analysis module with flow sensor, and flow sensor is mutually interconnected with perfusion tube It connects, induction detection is carried out to infusion rate;
The main control module amplifies conditioning circuit by blockage pressure and connect with pressure sensor, pressure sensor and perfusion tube phase It is intercommunicated, induction detection is carried out to infusion pressure.
2. a kind of medical micrometeor injection intelligence calibration system according to claim 1, it is characterised in that: the master control Module selects MSP430 single-chip microcontroller, and MSP430 main control part is made of MSP430F5438A minimum system, and minimum system is by JTAG Interface circuit, reset circuit and clock circuit three parts composition.
3. a kind of medical micrometeor injection intelligence calibration system according to claim 1, it is characterised in that: the CPLD Using the quartz oscillator of 20MHz as master clock signal source, support JTAG downloading mode to EPM240GT100C5N core Piece carries out on-line system programming and configuration, designs one 32 counters using CPLD logic analysis module, after clock division When the long-time that 3436s may be implemented in maximum is surveyed, when the most short 0.8us that can be realized is surveyed for a long time.
4. a kind of medical micrometeor injection intelligence calibration system according to claim 1, it is characterised in that: the pressure Sensor amplifies conditioning circuit and constitutes input stage with phase operational amplifier circuit by two, poor being composed in series three amplifiers with difference amplifier Divide amplifying circuit, related resistance keeps Striking symmetry in circuit.
CN201821780384.3U 2018-10-31 2018-10-31 A kind of medical micrometeor injection intelligence calibration system Expired - Fee Related CN209416456U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112393772A (en) * 2020-11-20 2021-02-23 南京信息职业技术学院 Insulin pump metering and calibrating device
CN112426585A (en) * 2020-11-20 2021-03-02 南京信息职业技术学院 Insulin pump metering calibration method
CN113884145A (en) * 2021-10-08 2022-01-04 成都创迪光电科技有限公司 High-precision real-time monitoring system for additive spraying of vacuum blood collection tube and flow collection method

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112393772A (en) * 2020-11-20 2021-02-23 南京信息职业技术学院 Insulin pump metering and calibrating device
CN112426585A (en) * 2020-11-20 2021-03-02 南京信息职业技术学院 Insulin pump metering calibration method
CN112426585B (en) * 2020-11-20 2022-04-29 南京信息职业技术学院 Insulin pump metering calibration method
CN112393772B (en) * 2020-11-20 2022-09-16 江苏省计量科学研究院 Insulin pump metering and calibrating device
CN113884145A (en) * 2021-10-08 2022-01-04 成都创迪光电科技有限公司 High-precision real-time monitoring system for additive spraying of vacuum blood collection tube and flow collection method

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