CN209400708U - Composite detecting device and system - Google Patents
Composite detecting device and system Download PDFInfo
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- CN209400708U CN209400708U CN201822115016.3U CN201822115016U CN209400708U CN 209400708 U CN209400708 U CN 209400708U CN 201822115016 U CN201822115016 U CN 201822115016U CN 209400708 U CN209400708 U CN 209400708U
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- inorganic scintillation
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- 239000002131 composite material Substances 0.000 title claims abstract description 35
- 239000013078 crystal Substances 0.000 claims abstract description 69
- 239000004033 plastic Substances 0.000 claims abstract description 45
- 229920003023 plastic Polymers 0.000 claims abstract description 45
- 238000001514 detection method Methods 0.000 claims description 14
- 238000003384 imaging method Methods 0.000 claims description 11
- 239000003292 glue Substances 0.000 claims description 9
- 150000001875 compounds Chemical class 0.000 claims description 7
- 230000003287 optical effect Effects 0.000 claims description 6
- 239000010410 layer Substances 0.000 claims description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 3
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 3
- 239000013307 optical fiber Substances 0.000 claims description 3
- 239000005304 optical glass Substances 0.000 claims description 3
- 239000000741 silica gel Substances 0.000 claims description 3
- 229910002027 silica gel Inorganic materials 0.000 claims description 3
- 229910052710 silicon Inorganic materials 0.000 claims description 3
- 239000010703 silicon Substances 0.000 claims description 3
- 239000002356 single layer Substances 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 1
- 230000005622 photoelectricity Effects 0.000 claims 1
- 239000000523 sample Substances 0.000 abstract description 30
- 230000005250 beta ray Effects 0.000 abstract description 14
- 230000005251 gamma ray Effects 0.000 abstract description 4
- 230000005855 radiation Effects 0.000 description 11
- 230000002285 radioactive effect Effects 0.000 description 10
- 238000000034 method Methods 0.000 description 9
- 238000012545 processing Methods 0.000 description 7
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- 238000004422 calculation algorithm Methods 0.000 description 6
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- 210000003205 muscle Anatomy 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 3
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- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 238000003491 array Methods 0.000 description 2
- ORCSMBGZHYTXOV-UHFFFAOYSA-N bismuth;germanium;dodecahydrate Chemical compound O.O.O.O.O.O.O.O.O.O.O.O.[Ge].[Ge].[Ge].[Bi].[Bi].[Bi].[Bi] ORCSMBGZHYTXOV-UHFFFAOYSA-N 0.000 description 2
- XQPRBTXUXXVTKB-UHFFFAOYSA-M caesium iodide Chemical compound [I-].[Cs+] XQPRBTXUXXVTKB-UHFFFAOYSA-M 0.000 description 2
- 238000004364 calculation method Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- ADOANNTYRWJJIS-UHFFFAOYSA-N lutetium silicic acid Chemical compound [Lu].[Si](O)(O)(O)O ADOANNTYRWJJIS-UHFFFAOYSA-N 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
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- 229910052727 yttrium Inorganic materials 0.000 description 2
- VWQVUPCCIRVNHF-UHFFFAOYSA-N yttrium atom Chemical compound [Y] VWQVUPCCIRVNHF-UHFFFAOYSA-N 0.000 description 2
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- 229910052765 Lutetium Inorganic materials 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000005260 alpha ray Effects 0.000 description 1
- JNDMLEXHDPKVFC-UHFFFAOYSA-N aluminum;oxygen(2-);yttrium(3+) Chemical compound [O-2].[O-2].[O-2].[Al+3].[Y+3] JNDMLEXHDPKVFC-UHFFFAOYSA-N 0.000 description 1
- 229910052788 barium Inorganic materials 0.000 description 1
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 description 1
- 229910001632 barium fluoride Inorganic materials 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
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- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- FAHBNUUHRFUEAI-UHFFFAOYSA-M hydroxidooxidoaluminium Chemical compound O[Al]=O FAHBNUUHRFUEAI-UHFFFAOYSA-M 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009940 knitting Methods 0.000 description 1
- XKUYOJZZLGFZTC-UHFFFAOYSA-K lanthanum(iii) bromide Chemical compound Br[La](Br)Br XKUYOJZZLGFZTC-UHFFFAOYSA-K 0.000 description 1
- OHSVLFRHMCKCQY-UHFFFAOYSA-N lutetium atom Chemical compound [Lu] OHSVLFRHMCKCQY-UHFFFAOYSA-N 0.000 description 1
- 238000009206 nuclear medicine Methods 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920002102 polyvinyl toluene Polymers 0.000 description 1
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- FVAUCKIRQBBSSJ-UHFFFAOYSA-M sodium iodide Chemical compound [Na+].[I-] FVAUCKIRQBBSSJ-UHFFFAOYSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 238000002834 transmittance Methods 0.000 description 1
Landscapes
- Measurement Of Radiation (AREA)
Abstract
The utility model discloses a kind of composite detecting device and system, which includes: plastic scintillant；Inorganic scintillation crystal array, one side are connect by first structure with the plastic scintillant；Photoelectric converter array, it is connect by the second structure with the other side far from the plastic scintillant in the inorganic scintillation crystal array, wherein, being polished at least one surface in two surfaces of the plastic scintillant and the photoelectric converter array contact in the inorganic scintillation crystal array.By utilizing composite detecting device provided by the utility model, the purpose of the gamma-ray complex probe to β ray and high-energy may be implemented, to expand dynamic detecting range.
Description
Technical field
The utility model relates to radiation detection field, in particular to a kind of composite detecting device and system.
Background technique
The description of this part only provides and discloses relevant background information to the utility model, without constituting the prior art.
Radiation detector can be widely applied to the fields such as nuclear medicine, safety check, astrophysics, autoradiograph.Mesh
Before, in autoradiograph field, existing radiation detector mainly includes following several types:
(1) radiation detector of plastic scintillant and charge-coupled device (CCD) is used, which mainly uses
Beta-ray radioactive isotope nucleic (for example,14C、35S、32P etc.) etc. as radioactive tracer, spatial resolution can
Reach some tens of pm, but the dynamic detecting range of the radiation detector is smaller, sensitivity is lower, can not be more than 30keV to energy
Gamma-rays detected, be not suitable for detecting the gamma-rays with higher-energy, and higher cost.
(2) radiation detector of fluorescence phosphorus screen technology is used, which is substantially carried out β ray and compared with low energy
The gamma-ray detection of (for example, 511keV or less), but the radiation detector be not suitable for yet to higher-energy (for example, high
In 511keV) gamma-rays detected.
Utility model content
The purpose of the utility model is to provide a kind of composite detecting device and systems, to realize simultaneously to β ray and high energy
The purpose that the gamma-rays of amount (that is, the energy for being higher than 511keV) is detected.
To achieve the goals above, the utility model provides a kind of composite detecting device comprising:
Plastic scintillant；
Inorganic scintillation crystal array, one side are connect by first structure with the plastic scintillant；
Photoelectric converter array passes through dodging in the second structure and the inorganic scintillation crystal array far from the plastics
The other side connection of bright body,
Wherein, in the inorganic scintillation crystal array with the plastic scintillant and the photoelectric converter array contact
Two surfaces at least one surface be polished.
Preferably, the plastic scintillant with a thickness of 0.01mm~5mm, length and width is 5mm~50mm.
Preferably, when the target sample is with a thickness of 20 μm~100 μm, positioned at the opposite of the target sample two sides
Two plastic scintillants between spacing be 1mm~10mm.
Preferably, the gap between two inorganic scintillation crystals adjacent in the inorganic scintillation crystal array is 0.05mm
~0.9mm, and the thickness of each inorganic scintillation crystal is 0.01mm~10mm.
Preferably, the photoelectric converter array include silicon photoelectric multiplier, photomultiplier tube, charge-coupled device and/
Or avalanche photodide.
Preferably, the first structure and second structure include bonded structure or adapting structure for electric and bonded structure
Combination.
Preferably, the bonded structure is made of optical glue, silica gel, AB glue and/or UV glue, and the adapting structure for electric includes
Optical light guides, optical glass or optical fiber.
Preferably, the adapting structure for electric is only partially cut or cuts entirely, and the width of the cutting gap of the adapting structure for electric
Degree is 0.1mm~0.5mm.
Preferably, the adapting structure for electric is single layer structure or for the multilayered structure less than 10 layers, and the undertaking is tied
The overall thickness of structure is 0.1mm~10mm.
The utility model additionally provides a kind of compound detection system, which includes above-mentioned composite detecting device
And for according to the composite detecting device to the detection result of target sample and to the target sample be imaged at
As device.
By the above technical solution provided by the utility model as it can be seen that the utility model is by utilizing plastic scintillant and inorganic
Scintillation crystal array combines to detect the radioactive ray issued from target sample, this may be implemented simultaneously to β ray and height
The purpose that the gamma-rays of energy (for example, up to 1000keV) is detected also expands to expand its dynamic detecting range
The application range of composite detecting device, also improves the spatial resolution of imaging.
Detailed description of the invention
It, below will be to embodiment or existing in order to illustrate more clearly of the utility model or technical solution in the prior art
Attached drawing needed in technical description is briefly described, it should be apparent that, the accompanying drawings in the following description is only this reality
With some embodiments of novel middle record, for those of ordinary skill in the art, before not making the creative labor property
It puts, is also possible to obtain other drawings based on these drawings.
Fig. 1 is a kind of structural schematic diagram of composite detecting device provided by the utility model；
Fig. 2 is another structural schematic diagram of composite detecting device provided by the utility model；
Fig. 3 is that the schematic diagram for detecting the object of radioactive ray is determined using the MVT method of sampling；
Fig. 4 is that the schematic diagram for detecting the object of radioactive ray is determined using CFD approach；
Fig. 5 is target sample image obtained when being rat brain tissue.
Specific embodiment
Below in conjunction with the attached drawing in the utility model, the technical solution in the utility model is carried out clearly and completely
Description, it is clear that described embodiment is only used for illustrating a part of the embodiment of the utility model, rather than all
Embodiment, it is undesirable that limitation the scope of the utility model or claims.Based on the embodiments of the present invention, originally
Field those of ordinary skill all other embodiment obtained without making creative work, all should belong to
The range of the utility model protection.
It should be noted that it can be arranged directly on another when element is referred to as on " setting exists " another element
On element or there may also be elements placed in the middle.When element is referred to as " connection/coupling " to another element, it be can be directly
Another element is connect/be coupled in succession or may be simultaneously present centering elements.Term as used herein " connection/coupling " can
To include electrical and/or mechanical-physical connection/coupling.Term as used herein "comprises/comprising" refers to feature, step or element
Presence, but the presence or addition of one or more other features, step or element is not precluded.Term as used herein
"and/or" includes any and all combinations of one or more related listed items.
Unless otherwise defined, all technical and scientific terms used herein are led with the technology for belonging to the utility model
The normally understood meaning of the technical staff in domain is identical.Term used herein is intended merely to the mesh of description specific embodiment
, and it is not intended to limitation the utility model.
In addition, in the description of the present invention, term " first ", " second " etc. be used for description purposes only it is similar with distinguishing
Object, between the two and be not present sequencing, indication or suggestion relative importance can not be interpreted as.In addition, in this reality
With in novel description, unless otherwise indicated, the meaning of " plurality " is two or more.
In the embodiments of the present invention, target sample, which can refer to, is injected with radioactive compound (that is, marking thereon
Have the compound of radionuclide) histotomy, organism is integrally sliced and/or cell smear etc., but not limited to this.Radiation
Property ray can refer to neutron ray, X-ray, gamma-rays, β ray and/or alpha ray etc..Electric signal can refer to that electric pulse is believed
Number, continuous electric signal or discrete electric signals etc..
Composite detecting device provided by the utility model is described in detail with reference to the accompanying drawing.
As shown in Figure 1, the utility model provides a kind of composite detecting device, it may include that the plastics set gradually dodge
Bright body 111, inorganic scintillation crystal array 112 and photoelectric converter array 113, wherein plastic scintillant 111 can be used for receiving
The radioactive ray that issues from target sample simultaneously generates corresponding first visible light signal, and inorganic scintillation crystal array 112 can be with
For receiving the radioactive ray issued from target sample and generating corresponding second visible light signal, photoelectric converter array
113 can be used for the first visible light signal and the second visible light signal being respectively converted into the first electric signal and the second electric signal.
Wherein, plastic scintillant 111 is connect by first structure with the side of inorganic scintillation crystal array 112, inorganic scintillation crystal battle array
The other side of separate plastic scintillant 111 in column 112 is connect by the second structure with photoelectric converter array 113.
In the embodiments of the present invention, plastic scintillant 111 can be used for receiving the radiation issued from target sample
Property ray (for example, β ray), generate corresponding first visible light signal and can by first by inorganic scintillation crystal array 112
Light-exposed signal is sent to photoelectric converter array 113, can also be transferred to the other radioactive rays issued from target sample
Inorganic scintillation crystal array 112.Plastic scintillant 111 can be made of multiple scintillator cells, and it can be by right
Polystyrene is processed and is obtained, and is also possible to obtain and processing polyvinyl-toluene, but be not limited to
In this.The thickness of plastic scintillant 111 can be 0.01mm~5mm, it is preferable that can be 0.25mm.Correspondingly, Plastic scintillation
The length and width of body 111 can be 5mm~50mm, it is preferable that can be 16mm, 18mm or 25mm etc..In addition, when modeling
When expecting that the quantity of scintillator 111 is multiple, opposite two plastic scintillant 111 positioned at target sample two sides is in length or thickness
Spacing on degree direction can be determined according to the thickness of target sample.For example, working as the thickness of target sample (for example, frozen section)
When degree is 20 μm~100 μm, the spacing d between two opposite plastic scintillants 111 can be 1mm~10mm, it is therefore preferable to
5mm, this is conducive to the spatial resolution for improving subsequent imaging.
Inorganic scintillation crystal array 112 can be used for receiving the radioactive ray issued from target sample (for example, γ is penetrated
Line), generate corresponding second visible light signal, and the second visible light signal and plastic scintillant 111 that are generated are sent
The first visible light signal be sent to photoelectric converter array 113.The quantity of inorganic scintillation crystal array 112 can be individually,
It is also possible to multiple.Each inorganic scintillation crystal array 112 can be made of single inorganic scintillation crystal, can also be by multiple
It is formed with identical size or various sizes of inorganic scintillation crystal.Inorganic scintillation crystal can be continuous crystal block, can also
To be part cutting or whole crystal items for cutting.Moreover, in inorganic scintillation crystal array 112, two adjacent inorganic sudden strains of a muscle
Gap between bright crystal can be 0.05mm~0.2mm, 0.05mm~0.10mm, 0.05mm~0.5mm, 0.5mm~0.9mm
Or 0.05~0.9mm, it is preferable that can be 0.05mm, 0.1mm, 0.15mm or 0.5mm etc.；Each inorganic scintillation crystal
Thickness can be 0.01mm~10mm, and the overall thickness of inorganic scintillation crystal array 112 can be less than 400mm, length
It can be identical or different with plastic scintillant 111 with width.In addition, the inorganic scintillation crystal in inorganic scintillation crystal array 112
It may include yttrium silicate (YSO) crystal, yttrium luetcium silicate (LYSO) crystal, silicic acid lutetium (LSO) crystal, bismuth germanium oxide (BGO) crystal, fluorine
Change barium (BaF2) crystal, lanthanum bromide (LaBr3) crystal, yttrium aluminate (YAP) crystal, aluminic acid lutetium (LuAP) crystal, sodium iodide (NaI)
One of crystal, cesium iodide (CsI) crystal etc. are a variety of, but not limited to this.
In addition, being contacted with plastic scintillant 111 and photoelectric converter array 113 in inorganic scintillation crystal array 112
At least one surface in two surfaces can be polished, and the first visible light signal of transmission and the second visible light letter can be improved in this
Number quantity, reduce light loss, so as to improve subsequent image quality and improve detection result accuracy.
The first visible light signal and inorganic sudden strain of a muscle that photoelectric converter array 113 can be used for generating plastic scintillant 111
The second visible light signal that bright crystal array 112 generates is respectively converted into the first electric signal and the second electric signal, and will be produced
The first electric signal and the second electric signal be sent to signal processor (not shown) and handled.Photoelectric converter array
113 may include one or more identical or different photoelectric converters, wherein each photoelectric converter can correspond to one
Or multiple inorganic scintillation crystals.In addition, the overall size of photoelectric converter array 113 can be with inorganic scintillation crystal array 112
Size is identical, can also be different.The size of each photoelectric converter can be according to the size of corresponding inorganic scintillation crystal come really
Determine or match with the size of inorganic scintillation crystal, for example, when inorganic scintillation crystal array 112 includes 40 × 40 inorganic sudden strains of a muscle
When bright crystal, overall size can be 16mm × 16mm × 3mm (length x width x thickness), 5 × 5 inorganic scintillation crystals pair
A photoelectric converter is answered, at this point, photoelectric converter array 113 may include 8 × 8 photoelectric converters, overall size can be with
For 16mm × 16mm × 1.5mm, the size of single photoelectric converter can be 2mm × 2mm × 1.5mm.In addition, photoelectric converter
Included photoelectric converter can be silicon photoelectric multiplier (SiPM), photomultiplier tube (APD) (for example, position in array 113
Responsive type photomultiplier tube (PSPMT)), charge-coupled device (CCD) or avalanche photodide (APD) be (for example, position sensing
Type avalanche photodide (PSAPD)) one of or it is a variety of, but not limited to this.
In addition, the quantity of photoelectric converter array 113 can be with plastic scintillant 111 and inorganic scintillation crystal array 112
Quantity it is corresponding, quantity may each be one or more.For example, inorganic Fig. 2 shows two plastic scintillant 111, two
Scintillation crystal array 112 and two photoelectric converter arrays 113, which constitute a pair of plates, wherein target sample is located at two
Between plastic scintillant 111.
First structure 114 and the second structure 115 can include the group of bonded structure or adapting structure for electric and bonded structure
It closes, wherein bonded structure can be to be made of optical glue, silica gel, AB glue and/or UV glue, and adapting structure for electric can be light transmittance
Solid light guide greater than 90%, for example, optical light guides (for example, acrylic piece), optical glass or optical fiber etc., are also possible to light transmission
Rate is greater than 90% light guide plate, but not limited to this.Adapting structure for electric is brilliant by bonded structure and plastic scintillant 111, Inorganic scintillation
Volume array 112 and photoelectric converter array 113 contact.Moreover, adapting structure for electric can be part cutting (for example, hemisect),
It can be and cut entirely, specific cutting mode can determine according to actual needs.In addition, the cutting gap of adapting structure for electric can be with
Corresponding with outermost multiple (for example, the 2-3) inorganic scintillation crystals of inorganic scintillation crystal array 112, width can be
0.1mm~0.5mm, 0.1mm~0.2mm, 0.2mm~0.3mm, 0.1mm~0.3mm, 0.1mm~0.4mm, 0.2mm~
0.4mm, 0.3mm~0.4mm, 0.3mm~0.5mm or 0.4mm~0.5mm, it is therefore preferable to 0.2mm, 0.3mm or 0.4mm.
In addition, adapting structure for electric can be single or multi-layer structure, for example, it may include 1~10 layer, each layer of thickness can phase
Together, it can also be different.The overall thickness of adapting structure for electric can be designed according to actual needs, for example, may be about 0.1mm~
10mm can preferably be 1.5mm~2mm, but not limited to this.In addition, the section shape of adapting structure for electric can for rectangle or
It is trapezoidal, it is also possible to other shapes.By utilizing adapting structure for electric to plastic scintillant 111, inorganic scintillation crystal array 112 and light
Electric transducer array 113 is accepted, this can effectively detect first issued from the fringe region of plastic scintillant 111 can
Light-exposed signal and the second visible light signal issued from the fringe region of inorganic scintillation crystal array 112, are visited so as to improve
Survey the accuracy of result.
In another embodiment of the utility model, which can also include signal multiplexing circuit (in figure
It is not shown), the first electric signal and the second electric signal that can be used for generating photoelectric converter array 113 carry out signal multiplexing
It handles and the first electric signal of inciting somebody to action that treated and the second electric signal is sent to signal processor.Specifically, signal multiplexing circuit
It may include at least one of following circuits: resistor network multiplex circuit, capacitance network multiplex circuit, transmission line multiplexing electricity
Road, right-angled intersection multiplex circuit and radio-frequency coil multiplex circuit.Wherein, resistor network multiplex circuit mainly will be from photoelectric conversion
X × y (wherein, x and y is the positive integer more than or equal to 2) road electric signal that device array 113 exports is converted into the road x+y electric signal,
It may then pass through and be converted to 4 road angle signals using the road the Yi Jiang x+y such as Anger-Logic algorithm in the prior art electric signal
(X+、X-、Y+And Y-) and 1 tunnel time signal.For example, the case where being 8 × 8 SiPM arrays for photoelectric converter array, pass through
The electric signal on 64 tunnels can be made to be reduced to 5 tunnels using resistor network multiplex circuit and Anger-Logic algorithm, this can be significantly
Reduce subsequent data calculation amount.About other multiplex circuits, it is referred to associated description in the prior art, it is no longer superfluous herein
It chats.By utilizing signal multiplexing circuit, it is possible to reduce subsequent data calculation amount, so as to improve data processing speed.
The composite detecting device can also include signal processor (not shown), can be chip, can also be with
It is the device with computing function, for example, computer.Signal processor can use the multivoltage threshold value method of sampling, number
Analog-to-digital conversion (ADC) method of sampling of change and the constant fraction discriminator of simulation determine that the methods of (CFD) method is come to photoelectric converter
The first electric signal and the second electric signal that array 113 generates or by multiplexed first electric signal of signal multiplexing circuit and the
Two electric signals are handled.For example, for the multivoltage threshold value method of sampling is utilized, signal processor can be used for according to default
Voltage threshold (for example, 4) samples the first electric signal and the second electric signal, records the first electric signal and the second electric signal
Amplitude reach the time of predetermined voltage threshold and the failing edge die-away time of the first electric signal and the second electric signal；According to institute
The failing edge die-away time of the first electric signal and the second electric signal that record determines the radiation that composite detecting device is detected
The type of property ray.For example, can then determine that plastics dodge when the failing edge die-away time of the first electric signal being about 3ns~5ns
Bright body 111 has detected β ray；When the failing edge die-away time of the second electric signal being about 40ns, then inorganic sudden strain of a muscle can be determined
Bright crystal array 112 has detected gamma-rays, as shown in Figure 3.Signal processor can be also used for according to the voltage recorded
Amplitude calculates the energy information of the first electric signal and the second electric signal, and detection is calculated according to obtained energy information
To the scintillator cells in Beta-ray plastic scintillant 111 position and detect gamma-ray inorganic scintillation crystal array 112
In inorganic scintillation crystal position.For another example for CFD approach is utilized, signal processor can be used for the first telecommunications
Number and the second electric signal be respectively divided into two path signal, i.e., the first electric signal is divided into first via electric signal A and the second tunnel telecommunications
Number A and the second electric signal is divided into first via electric signal B and the second road electric signal B, and can be used for first via telecommunications
The time of number A and first via electric signal B carries out delay disposal, carries out to the amplitude of the second road electric signal A and the second road electric signal B
Attenuation processing (concrete mode about delay disposal and attenuation processing is referred to the prior art, no longer superfluous herein to chat)；Comparison
The amplitude of the amplitude of first via electric signal A and the second road electric signal A and record first via electric signal A amplitude and second tunnel
The first time point when amplitude of electric signal A is equal, and the amplitude of first via electric signal B is compared with the second road electric signal B's
Amplitude and the second time point when the amplitude for recording first via electric signal B is equal with the amplitude of the second road electric signal B, described first
Time point and second time point are properly termed as zero-crossing timing point；Radiation is determined according to first time point and the second time point
The type of property ray.Specifically, if two path signal in the first electric signal reach the time of first time point be 3~
10ns can then determine that plastic scintillant 111 has detected β ray；If two path signal in the second electric signal reaches the
The time at two time points is 30~50ns, then can determine that inorganic scintillation crystal array 112 has detected gamma-rays, such as Fig. 4 institute
Show, may thereby determine that probe unit 110 has detected β ray and gamma-rays.Principle about the above-mentioned method of sampling can join
It is no longer superfluous herein to chat according to the prior art.
By determining the type of detected radioactive ray, the thing that decays caused by target sample can be determined
Part may thereby determine that out position where radionuclide, this can be accurately located radionuclide, so as to
Auxiliary carries out medical research to target sample.
The utility model additionally provides a kind of compound detection system, may include above-mentioned composite detecting device and imaging
Device, the imaging device target sample can be imaged the detection result of target sample according to composite detecting device,
It can be the self-contained unit with imaging function, for example, computer or projector；It is also possible to be integrated in self-contained unit
Module with imaging function.
It only include a pair of of plastic scintillant, inorganic scintillation crystal array and electrooptical device battle array for composite detecting device
The case where column, imaging device can be directly according to the positions of plastic scintillant and inorganic scintillation crystal array in signal processing results
The energy information of confidence breath and electric signal is imaged target sample；For composite detecting device include it is multipair (for example,
Two pairs) plastic scintillant, inorganic scintillation crystal array and the case where electrooptical device array (as shown in Figure 2), imaging device
It can further be done according to the temporal information of the electric signal in signal processing results and meet event handling, confirmed generated every
One meets event, then (can be thrown for example, filtering is anti-according to the obtained information for meeting event using parsing class algorithm
Shadow (FBP) algorithm) image reconstruction is carried out to electric signal, it also can use Class of Iterative algorithm (for example, order subset expectation maximization
(OSEM) algorithm and maximum a posteriori probability (MAP)) image reconstruction is carried out, but not limited to this.When target sample is rat brain group
When knitting, the image of obtained target sample can be as shown in Figure 5.In addition, can know that this is compound according to obtained image
The spatial resolution of detection system.For example, for photodetector array use the SiPM array of Sensl F30035 series with
And radioactive tracer be 18F-FDG the case where, spatial resolution can achieve 200 μm.
It can be seen from the above description that the utility model passes through using including that can detect Beta-ray plastic scintillant
Combination with the gamma-ray inorganic scintillation crystal array that can detect high-energy detects the radioactivity issued from target sample
Ray, the purpose detected simultaneously to the gamma-rays of β ray and high-energy may be implemented in this, to expand its detection dynamic
The application range of composite detecting device has also been enlarged in range.In addition, determining the radioactivity detected using signal processor
Ray is β ray or gamma-rays, this can determine decay event caused by target sample, may thereby determine that out and radiate
Property nucleic where position, this can be accurately located radionuclide, so as to assist curing target sample
Learn research.In addition, by the way that the sample after detection is imaged using imaging device, this can more intuitively object observing sample
The interior change of product, thus convenient medical diagnosis.In addition, the signal processor in the composite detecting device uses multivoltage
The threshold value method of sampling carries out sampling processing to electric signal, this time that can reduce subsequent imaging (generally only needs 2~10 points
Clock), it can achieve the effect of real time imagery, and the spatial resolution of image can also be improved.
Although the utility model provides composite detecting device and system as described in above-described embodiment or attached drawing, it is based on
It is conventional or without creative labor in composite detecting device provided by the utility model and system may include it is more or
The less component of person.
System, device, unit, module that above-described embodiment illustrates etc., specifically can be real by computer chip and/or entity
It is existing, or realized by the product with certain function.For convenience of description, it describes to be divided into when apparatus above with function various
Component describes respectively.It certainly, can be the function of each component in same or multiple calculating machine cores when implementing the utility model
It is realized in piece and/or entity.
All the embodiments in this specification are described in a progressive manner, same and similar portion between each embodiment
Dividing may refer to each other, and the highlights of each of the examples are differences from other embodiments.
Above-described embodiment be for convenient for those skilled in the art it will be appreciated that and using the utility model and
Description.Person skilled in the art obviously easily can make various modifications to these embodiments, and saying herein
Bright General Principle is applied in other embodiments without having to go through creative labor.Therefore, the utility model is not limited to
Embodiment is stated, those skilled in the art's announcement according to the present utility model does not depart from the improvement that the utility model scope is made
It should be all within the protection scope of the utility model with modification.
Claims (10)
1. a kind of composite detecting device characterized by comprising
Plastic scintillant；
Inorganic scintillation crystal array, one side are connect by first structure with the plastic scintillant；
Photoelectric converter array passes through the separate plastic scintillant in the second structure and the inorganic scintillation crystal array
The other side connection,
Wherein, two with the plastic scintillant and the photoelectric converter array contact in the inorganic scintillation crystal array
At least one surface in a surface is polished.
2. composite detecting device according to claim 1, which is characterized in that the plastic scintillant with a thickness of 0.01mm
~5mm, length and width are 5mm~50mm.
3. composite detecting device according to claim 1, which is characterized in that when target sample is with a thickness of 20 μm~100 μ
When m, the spacing between opposite two plastic scintillant of the target sample two sides is 1mm~10mm.
4. composite detecting device according to claim 1, which is characterized in that adjacent in the inorganic scintillation crystal array
Gap between two inorganic scintillation crystals is 0.05mm~0.9mm, and the thickness of each inorganic scintillation crystal is
0.01mm~10mm.
5. composite detecting device according to claim 1, which is characterized in that the photoelectric converter array includes silicon photoelectricity
Multiplier, photomultiplier tube, charge-coupled device and/or avalanche photodide.
6. composite detecting device according to claim 1, which is characterized in that the first structure and second structure are equal
Combination including bonded structure or adapting structure for electric and bonded structure.
7. composite detecting device according to claim 6, which is characterized in that the bonded structure by optical glue, silica gel,
AB glue and/or UV glue composition, the adapting structure for electric includes optical light guides, optical glass or optical fiber.
8. composite detecting device according to claim 6, which is characterized in that the adapting structure for electric is only partially cut or cuts entirely
It cuts, and the width of the cutting gap of the adapting structure for electric is 0.1mm~0.5mm.
9. according to composite detecting device described in claim 6,7 or 8, which is characterized in that the adapting structure for electric is single layer structure
It or is the multilayered structure less than 10 layers, and the overall thickness of the adapting structure for electric is 0.1mm~10mm.
10. a kind of compound detection system, which is characterized in that the compound detection system includes any in the claims 1-9
Described in composite detecting device and for according to the composite detecting device to the detection result of target sample and to described
The imaging device that target sample is imaged.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822115016.3U CN209400708U (en) | 2018-12-17 | 2018-12-17 | Composite detecting device and system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201822115016.3U CN209400708U (en) | 2018-12-17 | 2018-12-17 | Composite detecting device and system |
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| CN209400708U true CN209400708U (en) | 2019-09-17 |
Family
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111638540A (en) * | 2020-05-27 | 2020-09-08 | 北京市射线应用研究中心 | Device, method, equipment and storage medium for measuring radioactive inert gas |
| WO2023197627A1 (en) * | 2022-04-11 | 2023-10-19 | 苏州瑞派宁科技有限公司 | Multilayer crystal, detector and multilayer crystal bonding method |
-
2018
- 2018-12-17 CN CN201822115016.3U patent/CN209400708U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111638540A (en) * | 2020-05-27 | 2020-09-08 | 北京市射线应用研究中心 | Device, method, equipment and storage medium for measuring radioactive inert gas |
| WO2023197627A1 (en) * | 2022-04-11 | 2023-10-19 | 苏州瑞派宁科技有限公司 | Multilayer crystal, detector and multilayer crystal bonding method |
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